[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr3:153,142,317-154,733,231

Best TWAS P=6.5e-12 · Best GWAS P=5.16e-12 conditioned to 3.56e-11

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DHX36	0.05	0.06	blup	357	0.05	1.3e-06	5.8	6.9	6.5e-12	-0.04	0.04	0.96	TRUE
2	GTEx	Adipose Subcutaneous	ARHGEF26	0.10	0.06	enet	8	0.07	2.2e-06	5.8	-6.0	1.8e-09	0.07	0.07	0.93	FALSE
3	GTEx	Artery Tibial	ARHGEF26	0.11	0.12	enet	12	0.12	5.9e-10	5.9	-6.3	3.3e-10	0.05	0.05	0.95	FALSE
4	GTEx	Breast Mammary Tissue	DHX36	0.15	0.07	enet	14	0.05	9.4e-04	6.0	5.8	7.6e-09	-0.09	0.08	0.91	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	DHX36	0.19	0.16	lasso	7	0.12	6.1e-05	6.0	5.8	8.1e-09	-0.10	0.06	0.94	FALSE
6	GTEx	Pancreas	ARHGEF26	0.26	0.26	lasso	5	0.28	3.2e-12	5.8	-5.8	7.7e-09	0.06	0.07	0.93	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	ARHGEF26	0.13	0.11	lasso	4	0.07	6.8e-05	5.8	-5.6	2.4e-08	0.06	0.06	0.94	FALSE
8	GTEx	Thyroid	ARHGEF26	0.09	0.07	enet	17	0.08	1.9e-06	5.9	-5.5	4.4e-08	0.04	0.05	0.95	FALSE
9	GTEx	Thyroid	DHX36	0.06	0.01	lasso	4	0.02	1.7e-02	5.2	5.3	1.5e-07	0.02	0.09	0.76	FALSE
10	METSIM	Adipose	ARHGEF26	0.07	0.08	lasso	6	0.07	3.5e-11	5.8	-5.3	1.1e-07	-0.04	0.04	0.96	FALSE
11	YFS	Blood	DHX36	0.11	0.19	lasso	11	0.21	9.1e-68	5.0	5.5	3.6e-08	-0.06	0.93	0.07	FALSE
12	The Cancer Genome Atlas	Glioblastoma Multiforme	SGEF	0.17	0.13	blup	74	0.14	5.5e-05	6.1	5.5	3.0e-08	-0.09	0.02	0.90	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DHX36	0.07	0.06	lasso	6	0.08	4.8e-09	5.0	5.4	5.9e-08	-0.06	0.03	0.97	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SGEF	0.04	0.04	enet	12	0.04	1.1e-05	6.0	-6.4	2.0e-10	0.08	0.03	0.96	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	DHX36	0.11	0.09	enet	11	0.10	6.4e-12	5.3	5.9	3.7e-09	0.01	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	DHX36	0.09	0.07	blup	50	0.07	1.6e-08	4.9	5.3	1.2e-07	-0.07	0.03	0.96	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DHX36	0.08	0.02	blup	50	0.03	1.4e-02	5.2	5.7	1.6e-08	-0.06	0.01	0.87	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	DHX36	0.11	0.11	lasso	8	0.13	8.5e-14	4.9	5.4	6.4e-08	-0.06	0.03	0.96	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	DHX36	0.16	0.17	blup	50	0.19	7.7e-18	4.9	5.7	1.4e-08	-0.08	0.03	0.96	FALSE