[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr3:157,125,828-159,106,064

Best TWAS P=5.1e-11 · Best GWAS P=1.54e-08 conditioned to 0.774

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RSRC1	0.15	0.17	lasso	4	0.18	9.7e-15	5.0	-5.8	5.3e-09	-0.51	0.26	0.74	FALSE
2	GTEx	Adipose Subcutaneous	RP11-538P18.2	0.15	0.15	lasso	7	0.18	9.4e-15	5.0	-5.7	1.0e-08	-0.72	0.23	0.77	FALSE
3	GTEx	Adipose Visceral Omentum	RSRC1	0.16	0.08	enet	12	0.09	2.5e-05	5.5	-6.1	1.2e-09	-0.89	0.03	0.97	FALSE
4	GTEx	Adipose Visceral Omentum	RP11-538P18.2	0.23	0.10	enet	22	0.16	1.2e-08	5.5	-6.1	1.0e-09	-0.85	0.03	0.97	FALSE
5	GTEx	Artery Aorta	RSRC1	0.09	0.04	lasso	5	0.03	1.4e-02	4.9	-5.2	2.3e-07	-0.86	0.09	0.81	FALSE
6	GTEx	Artery Aorta	RP11-538P18.2	0.11	0.09	lasso	3	0.08	2.9e-05	5.1	-5.6	2.7e-08	-0.69	0.17	0.82	FALSE
7	GTEx	Artery Tibial	RSRC1	0.13	0.13	lasso	6	0.11	3.5e-09	5.0	-5.4	7.6e-08	-0.59	0.24	0.76	FALSE
8	GTEx	Artery Tibial	RP11-538P18.2	0.17	0.14	enet	24	0.21	3.7e-16	5.0	-5.8	8.5e-09	-0.77	0.30	0.70	FALSE
9	GTEx	Breast Mammary Tissue	RSRC1	0.14	0.10	lasso	6	0.13	4.9e-07	5.0	-6.2	4.5e-10	-0.54	0.26	0.73	FALSE
10	GTEx	Breast Mammary Tissue	RP11-538P18.2	0.17	0.14	lasso	6	0.16	1.2e-08	5.0	-5.2	2.3e-07	-0.57	0.29	0.71	FALSE
11	GTEx	Cells Transformed fibroblasts	RP11-538P18.2	0.10	0.08	enet	10	0.13	5.1e-10	5.0	-5.7	1.4e-08	-0.78	0.22	0.78	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	RP11-538P18.2	0.21	0.12	lasso	4	0.12	3.5e-05	5.0	-6.0	2.7e-09	-0.90	0.03	0.94	FALSE
13	GTEx	Esophagus Mucosa	RSRC1	0.09	0.02	enet	20	0.04	9.3e-04	5.5	-5.3	9.7e-08	-0.66	0.04	0.89	FALSE
14	GTEx	Esophagus Mucosa	RP11-538P18.2	0.12	0.10	lasso	5	0.14	1.9e-09	5.0	-5.5	3.2e-08	-0.62	0.07	0.93	FALSE
15	GTEx	Heart Atrial Appendage	RP11-379F4.7	0.07	0.09	enet	11	0.01	1.4e-01	5.1	5.5	3.8e-08	0.87	0.08	0.76	FALSE
16	GTEx	Lung	RP11-538P18.2	0.16	0.11	enet	17	0.17	6.6e-13	4.7	-5.4	5.9e-08	-0.67	0.42	0.57	FALSE
17	GTEx	Lung	RP11-379F4.7	0.05	0.01	lasso	3	0.01	1.2e-01	5.5	6.6	5.1e-11	0.84	0.04	0.77	TRUE
18	GTEx	Muscle Skeletal	RP11-538P18.2	0.09	0.08	lasso	2	0.05	1.3e-05	5.0	-5.3	1.1e-07	-0.61	0.27	0.72	FALSE
19	GTEx	Nerve Tibial	RSRC1	0.10	0.15	lasso	3	0.12	9.9e-09	5.0	-5.2	1.5e-07	-0.53	0.27	0.73	FALSE
20	GTEx	Ovary	RP11-538P18.2	0.23	0.08	lasso	6	0.13	4.5e-04	5.0	-5.6	2.2e-08	-0.82	0.08	0.21	FALSE
21	GTEx	Pancreas	RP11-538P18.2	0.14	0.02	lasso	11	0.02	5.3e-02	5.1	-5.8	7.8e-09	-0.86	0.04	0.85	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	RP11-538P18.2	0.09	0.10	enet	13	0.12	6.8e-07	4.7	-6.0	2.7e-09	-0.86	0.05	0.95	FALSE
23	GTEx	Skin Sun Exposed Lower leg	RP11-538P18.2	0.13	0.12	enet	11	0.14	7.8e-12	5.0	-5.7	1.2e-08	-0.74	0.21	0.79	FALSE
24	GTEx	Stomach	RSRC1	0.08	0.06	lasso	3	0.07	2.9e-04	5.0	-5.6	2.4e-08	-0.89	0.04	0.94	FALSE
25	GTEx	Thyroid	RSRC1	0.07	0.04	lasso	7	0.02	8.5e-03	5.5	-5.6	2.4e-08	-0.95	0.03	0.96	FALSE
26	GTEx	Thyroid	RP11-538P18.2	0.14	0.13	lasso	5	0.12	1.2e-09	5.0	-5.2	2.3e-07	-0.64	0.24	0.76	FALSE
27	GTEx	Vagina	RP11-538P18.2	0.25	0.19	lasso	3	0.18	6.7e-05	5.4	-5.6	2.7e-08	-0.83	0.06	0.62	FALSE
28	METSIM	Adipose	RSRC1	0.14	0.19	blup	532	0.21	6.0e-31	5.0	-5.5	3.4e-08	-0.55	0.27	0.73	FALSE
29	The Cancer Genome Atlas	Brain Lower Grade Glioma	RSRC1	0.05	0.03	blup	154	0.01	7.9e-03	5.0	-6.0	1.8e-09	-0.83	0.08	0.68	FALSE