[Hub]/) : Traits : Systolic Blood Pressure :

chr3:157,125,828-159,106,064

Best TWAS P=5.1e-11 · Best GWAS P=1.54e-08 conditioned to 0.774

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RSRC1 0.15 0.17 lasso 4 0.18 9.7e-15 5.0 -5.8 5.3e-09 -0.51 0.26 0.74 FALSE
2 GTEx Adipose Subcutaneous RP11-538P18.2 0.15 0.15 lasso 7 0.18 9.4e-15 5.0 -5.7 1.0e-08 -0.72 0.23 0.77 FALSE
3 GTEx Adipose Visceral Omentum RSRC1 0.16 0.08 enet 12 0.09 2.5e-05 5.5 -6.1 1.2e-09 -0.89 0.03 0.97 FALSE
4 GTEx Adipose Visceral Omentum RP11-538P18.2 0.23 0.10 enet 22 0.16 1.2e-08 5.5 -6.1 1.0e-09 -0.85 0.03 0.97 FALSE
5 GTEx Artery Aorta RSRC1 0.09 0.04 lasso 5 0.03 1.4e-02 4.9 -5.2 2.3e-07 -0.86 0.09 0.81 FALSE
6 GTEx Artery Aorta RP11-538P18.2 0.11 0.09 lasso 3 0.08 2.9e-05 5.1 -5.6 2.7e-08 -0.69 0.17 0.82 FALSE
7 GTEx Artery Tibial RSRC1 0.13 0.13 lasso 6 0.11 3.5e-09 5.0 -5.4 7.6e-08 -0.59 0.24 0.76 FALSE
8 GTEx Artery Tibial RP11-538P18.2 0.17 0.14 enet 24 0.21 3.7e-16 5.0 -5.8 8.5e-09 -0.77 0.30 0.70 FALSE
9 GTEx Breast Mammary Tissue RSRC1 0.14 0.10 lasso 6 0.13 4.9e-07 5.0 -6.2 4.5e-10 -0.54 0.26 0.73 FALSE
10 GTEx Breast Mammary Tissue RP11-538P18.2 0.17 0.14 lasso 6 0.16 1.2e-08 5.0 -5.2 2.3e-07 -0.57 0.29 0.71 FALSE
11 GTEx Cells Transformed fibroblasts RP11-538P18.2 0.10 0.08 enet 10 0.13 5.1e-10 5.0 -5.7 1.4e-08 -0.78 0.22 0.78 FALSE
12 GTEx Esophagus Gastroesophageal Junction RP11-538P18.2 0.21 0.12 lasso 4 0.12 3.5e-05 5.0 -6.0 2.7e-09 -0.90 0.03 0.94 FALSE
13 GTEx Esophagus Mucosa RSRC1 0.09 0.02 enet 20 0.04 9.3e-04 5.5 -5.3 9.7e-08 -0.66 0.04 0.89 FALSE
14 GTEx Esophagus Mucosa RP11-538P18.2 0.12 0.10 lasso 5 0.14 1.9e-09 5.0 -5.5 3.2e-08 -0.62 0.07 0.93 FALSE
15 GTEx Heart Atrial Appendage RP11-379F4.7 0.07 0.09 enet 11 0.01 1.4e-01 5.1 5.5 3.8e-08 0.87 0.08 0.76 FALSE
16 GTEx Lung RP11-538P18.2 0.16 0.11 enet 17 0.17 6.6e-13 4.7 -5.4 5.9e-08 -0.67 0.42 0.57 FALSE
17 GTEx Lung RP11-379F4.7 0.05 0.01 lasso 3 0.01 1.2e-01 5.5 6.6 5.1e-11 0.84 0.04 0.77 TRUE
18 GTEx Muscle Skeletal RP11-538P18.2 0.09 0.08 lasso 2 0.05 1.3e-05 5.0 -5.3 1.1e-07 -0.61 0.27 0.72 FALSE
19 GTEx Nerve Tibial RSRC1 0.10 0.15 lasso 3 0.12 9.9e-09 5.0 -5.2 1.5e-07 -0.53 0.27 0.73 FALSE
20 GTEx Ovary RP11-538P18.2 0.23 0.08 lasso 6 0.13 4.5e-04 5.0 -5.6 2.2e-08 -0.82 0.08 0.21 FALSE
21 GTEx Pancreas RP11-538P18.2 0.14 0.02 lasso 11 0.02 5.3e-02 5.1 -5.8 7.8e-09 -0.86 0.04 0.85 FALSE
22 GTEx Skin Not Sun Exposed Suprapubic RP11-538P18.2 0.09 0.10 enet 13 0.12 6.8e-07 4.7 -6.0 2.7e-09 -0.86 0.05 0.95 FALSE
23 GTEx Skin Sun Exposed Lower leg RP11-538P18.2 0.13 0.12 enet 11 0.14 7.8e-12 5.0 -5.7 1.2e-08 -0.74 0.21 0.79 FALSE
24 GTEx Stomach RSRC1 0.08 0.06 lasso 3 0.07 2.9e-04 5.0 -5.6 2.4e-08 -0.89 0.04 0.94 FALSE
25 GTEx Thyroid RSRC1 0.07 0.04 lasso 7 0.02 8.5e-03 5.5 -5.6 2.4e-08 -0.95 0.03 0.96 FALSE
26 GTEx Thyroid RP11-538P18.2 0.14 0.13 lasso 5 0.12 1.2e-09 5.0 -5.2 2.3e-07 -0.64 0.24 0.76 FALSE
27 GTEx Vagina RP11-538P18.2 0.25 0.19 lasso 3 0.18 6.7e-05 5.4 -5.6 2.7e-08 -0.83 0.06 0.62 FALSE
28 METSIM Adipose RSRC1 0.14 0.19 blup 532 0.21 6.0e-31 5.0 -5.5 3.4e-08 -0.55 0.27 0.73 FALSE
29 The Cancer Genome Atlas Brain Lower Grade Glioma RSRC1 0.05 0.03 blup 154 0.01 7.9e-03 5.0 -6.0 1.8e-09 -0.83 0.08 0.68 FALSE