[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr3:159,248,823-161,788,101

Best TWAS P=9.32e-13 · Best GWAS P=4.9e-11 conditioned to 0.796

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	IFT80	0.08	0.06	enet	35	0.06	1.5e-07	6.3	-5.4	8.5e-08	-0.75	0.08	0.92	FALSE
2	CommonMind	Brain Pre-frontal Cortex	KPNA4	0.14	0.21	lasso	5	0.21	1.0e-24	6.5	6.5	7.5e-11	0.96	0.03	0.97	FALSE
3	CommonMind	Brain Pre-frontal Cortex	NMD3	0.11	0.13	blup	351	0.16	1.9e-18	-4.5	-5.1	2.8e-07	-0.16	0.16	0.83	FALSE
4	CommonMind	Brain Pre-frontal Cortex	TRIM59	0.03	0.01	blup	379	0.01	3.1e-02	6.3	-6.9	6.6e-12	-0.86	0.05	0.92	FALSE
5	GTEx	Brain Cortex	IFT80	0.15	0.09	lasso	3	0.04	2.5e-02	-6.0	-6.5	1.1e-10	-0.61	0.08	0.73	FALSE
6	GTEx	Brain Frontal Cortex BA9	PPM1L	0.18	0.13	enet	23	0.07	6.5e-03	6.4	6.2	5.4e-10	0.92	0.05	0.84	FALSE
7	GTEx	Cells Transformed fibroblasts	NMD3	0.08	0.02	lasso	3	0.00	1.7e-01	-5.2	-5.4	5.7e-08	-0.14	0.10	0.44	FALSE
8	GTEx	Esophagus Muscularis	SMC4	0.08	0.08	lasso	2	0.05	4.6e-04	6.3	6.3	2.2e-10	0.92	0.05	0.94	FALSE
9	GTEx	Skin Sun Exposed Lower leg	NMD3	0.10	0.02	lasso	6	0.01	2.5e-02	-5.6	5.5	4.5e-08	0.08	0.06	0.75	FALSE
10	GTEx	Testis	KPNA4	0.14	0.04	enet	21	0.06	1.7e-03	-4.5	-5.3	1.1e-07	-0.69	0.06	0.90	FALSE
11	METSIM	Adipose	SPTSSB	0.04	0.07	lasso	8	0.06	5.1e-09	-5.7	-5.6	1.7e-08	-0.08	0.02	0.98	FALSE
12	YFS	Blood	KPNA4	0.02	0.02	lasso	6	0.01	6.7e-05	-6.0	-5.4	6.2e-08	-0.68	0.32	0.46	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	C3orf57	0.02	0.01	blup	51	0.01	1.1e-02	-5.9	-6.0	1.5e-09	-0.04	0.01	0.97	TRUE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM59	0.01	0.01	blup	41	0.01	7.8e-04	-6.0	-7.1	1.2e-12	-0.76	0.05	0.68	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SMC4	0.04	0.03	lasso	3	0.02	9.9e-04	-6.1	-5.5	4.4e-08	-0.34	0.08	0.64	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIM59	0.05	0.08	lasso	2	0.09	9.4e-11	6.3	-6.5	1.1e-10	-0.90	0.03	0.97	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	IFT80	0.03	0.02	blup	94	0.02	3.1e-03	-6.1	-6.9	4.0e-12	-0.77	0.07	0.77	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIM59	0.04	0.01	blup	41	0.02	7.0e-04	6.5	-7.1	9.3e-13	-0.87	0.01	0.97	TRUE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	TRIM59	0.02	0.01	blup	41	0.01	1.4e-02	-6.0	-6.2	7.5e-10	-0.86	0.02	0.65	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM59	0.02	0.02	blup	41	0.02	8.0e-03	6.3	-6.5	9.1e-11	-0.93	0.02	0.78	FALSE