[Hub]/) : Traits : Schizophrenia (2014) :

chr12:122,713,991-124,591,385

Best TWAS P=1.74e-11 · Best GWAS P=1.74e-11 conditioned to 0.0195

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum ARL6IP4 0.08 0.02 lasso 5 0.06 3.7e-04 -3.6 -5.3 1.5e-07 -0.80 0.12 0.54 FALSE
2 GTEx Adipose Visceral Omentum RP11-282O18.3 0.14 0.11 enet 12 0.10 6.7e-06 4.8 -5.2 1.8e-07 -0.83 0.65 0.34 FALSE
3 GTEx Artery Tibial MPHOSPH9 0.05 0.03 lasso 3 0.03 2.2e-03 5.1 5.3 1.4e-07 0.81 0.35 0.42 FALSE
4 GTEx Artery Tibial ABCB9 0.04 0.02 lasso 2 0.01 3.0e-02 5.2 5.5 4.6e-08 0.92 0.04 0.92 FALSE
5 GTEx Breast Mammary Tissue (Female) CDK2AP1 0.08 0.03 lasso 3 0.02 6.4e-02 4.9 -5.9 4.5e-09 -0.94 0.04 0.74 FALSE
6 GTEx Breast Mammary Tissue (Female) RP11-282O18.3 0.09 0.07 enet 8 0.08 2.8e-03 5.3 -5.7 9.7e-09 -0.92 0.04 0.90 FALSE
7 GTEx Cells Transformed fibroblasts OGFOD2 0.10 0.07 lasso 7 0.07 3.1e-06 5.5 5.5 2.9e-08 0.93 0.24 0.76 FALSE
8 GTEx Cells Transformed fibroblasts C12orf65 0.07 0.05 lasso 4 0.04 5.8e-04 4.6 -5.8 8.6e-09 -0.86 0.03 0.96 FALSE
9 GTEx Cells Transformed fibroblasts ABCB9 0.08 0.12 enet 7 0.12 4.3e-09 5.3 5.7 1.5e-08 0.89 0.74 0.26 FALSE
10 GTEx Cells Transformed fibroblasts ARL6IP4 0.12 0.13 lasso 2 0.12 4.0e-09 5.3 -5.4 8.6e-08 -0.85 0.64 0.36 FALSE
11 GTEx Cells Transformed fibroblasts SETD8 0.10 0.12 enet 9 0.09 1.4e-07 4.6 5.6 2.7e-08 0.85 0.21 0.79 FALSE
12 GTEx Colon Sigmoid CDK2AP1 0.12 0.02 enet 12 0.11 1.1e-04 4.7 -5.4 5.2e-08 -0.73 0.18 0.73 FALSE
13 GTEx Colon Sigmoid ABCB9 0.18 0.16 lasso 6 0.15 4.8e-06 4.9 5.2 1.8e-07 0.88 0.17 0.79 FALSE
14 GTEx Colon Transverse ABCB9 0.08 0.07 enet 5 0.09 5.3e-05 4.5 5.3 1.4e-07 0.88 0.07 0.90 FALSE
15 GTEx Esophagus Mucosa ABCB9 0.10 0.03 lasso 5 0.05 5.4e-04 4.8 5.2 1.6e-07 0.87 0.07 0.92 FALSE
16 GTEx Esophagus Muscularis C12orf65 0.06 0.04 lasso 4 0.04 2.0e-03 4.9 -5.3 1.1e-07 -0.84 0.24 0.66 FALSE
17 GTEx Heart Left Ventricle MPHOSPH9 0.06 0.04 lasso 5 0.04 4.2e-03 5.4 5.9 3.1e-09 0.84 0.03 0.91 FALSE
18 GTEx Heart Left Ventricle ABCB9 0.10 0.14 lasso 5 0.10 4.2e-06 6.5 6.4 1.5e-10 0.95 0.01 0.98 FALSE
19 GTEx Liver ABCB9 0.32 0.32 lasso 3 0.28 1.9e-08 5.3 5.3 9.3e-08 0.88 0.28 0.66 FALSE
20 GTEx Lung ABCB9 0.04 0.02 lasso 3 0.02 8.0e-03 5.3 5.6 2.6e-08 0.88 0.10 0.77 FALSE
21 GTEx Muscle Skeletal SETD8 0.16 0.02 lasso 4 0.03 3.8e-04 4.9 5.6 2.3e-08 0.79 0.60 0.27 FALSE
22 GTEx Nerve Tibial C12orf65 0.05 0.07 lasso 3 0.06 3.0e-05 5.1 -5.3 1.0e-07 -0.78 0.23 0.60 FALSE
23 GTEx Pancreas ARL6IP4 0.07 0.07 lasso 2 0.07 9.6e-04 6.5 -6.1 1.3e-09 -0.93 0.04 0.86 FALSE
24 GTEx Skin Not Sun Exposed Suprapubic ABCB9 0.13 0.15 lasso 11 0.11 2.1e-06 5.3 5.9 3.7e-09 0.93 0.03 0.97 FALSE
25 GTEx Skin Sun Exposed Lower leg ABCB9 0.09 0.08 lasso 5 0.08 4.3e-07 5.3 6.0 2.3e-09 0.93 0.03 0.97 FALSE
26 GTEx Small Intestine Terminal Ileum ABCB9 0.23 0.21 enet 12 0.22 1.0e-05 5.3 5.5 4.9e-08 0.78 0.16 0.48 FALSE
27 GTEx Testis MPHOSPH9 0.28 0.27 enet 23 0.32 1.3e-14 5.4 5.8 5.3e-09 0.93 0.06 0.94 FALSE
28 GTEx Testis CDK2AP1 0.20 0.14 lasso 5 0.13 2.0e-06 6.5 -6.6 5.1e-11 -0.95 0.01 0.99 FALSE
29 GTEx Testis RP11-282O18.3 0.18 0.09 lasso 9 0.12 7.8e-06 6.5 -5.9 3.4e-09 -0.85 0.01 0.96 FALSE
30 GTEx Thyroid MPHOSPH9 0.10 0.08 enet 20 0.09 2.0e-07 5.3 5.5 4.1e-08 0.88 0.08 0.92 FALSE
31 YFS Blood MPHOSPH9 0.05 0.07 enet 31 0.07 3.7e-23 5.0 5.2 1.7e-07 0.86 0.73 0.27 FALSE
32 The Cancer Genome Atlas Bladder Urothelial Carcinoma OGFOD2 0.03 0.02 blup 16 0.01 5.0e-02 5.2 5.3 9.2e-08 0.86 0.01 0.83 FALSE
33 The Cancer Genome Atlas Breast Invasive Carcinoma C12orf65 0.02 0.00 enet 6 0.01 2.4e-03 6.5 -5.9 2.9e-09 -0.82 0.01 0.80 FALSE
34 The Cancer Genome Atlas Breast Invasive Carcinoma CDK2AP1 0.07 0.08 lasso 7 0.08 5.0e-16 4.7 -5.1 2.9e-07 -0.85 0.61 0.39 FALSE
35 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CDK2AP1 0.07 0.07 blup 34 0.05 1.1e-03 5.3 -5.3 1.4e-07 -0.80 0.02 0.81 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C12orf65 0.04 0.03 enet 18 0.03 4.9e-04 6.5 -6.4 2.1e-10 -0.75 0.01 0.92 FALSE
37 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C12orf65 0.05 0.04 blup 34 0.05 1.0e-03 5.2 -6.1 8.6e-10 -0.95 0.01 0.91 FALSE
38 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PITPNM2 0.06 0.07 lasso 5 0.09 1.2e-05 5.4 -5.7 1.5e-08 -0.88 0.06 0.94 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma C12orf65 0.03 0.01 blup 35 0.02 1.6e-03 6.4 -5.9 4.6e-09 -0.89 0.01 0.87 FALSE
40 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABCB9 0.19 0.22 enet 9 0.22 7.7e-11 5.2 5.8 6.5e-09 0.88 0.01 0.99 FALSE
41 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ABCB9 0.06 0.06 enet 7 0.07 5.2e-08 5.4 5.6 2.5e-08 0.91 0.01 0.99 FALSE
42 The Cancer Genome Atlas Lung Squamous Cell Carcinoma OGFOD2 0.02 0.04 lasso 3 0.03 1.3e-04 5.3 5.3 1.1e-07 0.88 0.01 0.95 FALSE
43 The Cancer Genome Atlas Pancreatic Adenocarcinoma CDK2AP1 0.12 0.14 blup 34 0.15 7.2e-07 6.5 -5.7 1.1e-08 -0.86 0.01 0.98 FALSE
44 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ABCB9 0.17 0.13 enet 6 0.11 3.9e-05 5.2 5.2 1.8e-07 0.74 0.01 0.98 FALSE
45 The Cancer Genome Atlas Prostate Adenocarcinoma ABCB9 0.04 0.05 enet 10 0.05 1.2e-05 5.3 5.5 5.0e-08 0.90 0.01 0.99 FALSE
46 The Cancer Genome Atlas Stomach Adenocarcinoma CDK2AP1 0.09 0.10 lasso 2 0.10 1.8e-07 4.7 -5.3 1.2e-07 -0.86 0.03 0.97 FALSE
47 The Cancer Genome Atlas Testicular Germ Cell Tumors CDK2AP1 0.13 0.10 blup 34 0.11 8.2e-05 6.5 -6.0 2.4e-09 -0.93 0.01 0.97 FALSE
48 The Cancer Genome Atlas Thyroid Carcinoma OGFOD2 0.02 0.00 enet 4 0.02 2.7e-03 5.4 6.3 2.8e-10 0.88 0.01 0.61 FALSE
49 The Cancer Genome Atlas Thyroid Carcinoma PITPNM2 0.04 0.03 enet 5 0.05 8.1e-06 4.8 6.7 1.7e-11 0.78 0.02 0.98 TRUE