Best TWAS P=8.7e-11 · Best GWAS P=1.24e-13 conditioned to 0.0144
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Small Intestine Terminal Ileum | C2orf82 | 0.45 | -0.01 | lasso | 6 | 0.00 | 2.6e-01 | 6.7 | 5.2 | 1.5e-07 | 0.78 | 0.03 | 0.43 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | NGEF | 0.14 | 0.03 | lasso | 4 | 0.03 | 6.2e-03 | 6.6 | 6.1 | 8.1e-10 | 0.47 | 0.05 | 0.16 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | EFHD1 | 0.11 | 0.01 | blup | 70 | 0.03 | 1.0e-02 | 7.1 | 6.2 | 6.3e-10 | 0.60 | 0.00 | 0.89 | FALSE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | NGEF | 0.28 | 0.11 | enet | 11 | 0.18 | 1.1e-05 | 6.7 | 5.8 | 6.5e-09 | 0.47 | 0.10 | 0.26 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | KCNJ13 | 0.03 | 0.00 | blup | 35 | 0.01 | 4.3e-02 | 7.0 | -6.1 | 1.2e-09 | -0.66 | 0.01 | 0.64 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | NGEF | 0.04 | 0.03 | enet | 7 | 0.03 | 5.6e-04 | 6.9 | -6.5 | 8.7e-11 | -0.76 | 0.06 | 0.89 | TRUE |