TWAS hub - C2orf82

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1430	0.0280	0.0e+00	0.224	0.172	0.223	0.220	0.227	7.2e-27	2.0e-20	1.1e-26	2.7e-26	3.8e-27
2	GTEx	Brain Caudate basal ganglia	0.2740	0.0940	3.8e-04	0.263	NA	0.137	NA	0.244	3.3e-08	NA	9.8e-05	NA	1.2e-07
3	GTEx	Brain Cerebellum	0.1480	0.0630	7.8e-03	0.185	NA	0.098	NA	0.130	3.9e-06	NA	8.1e-04	NA	1.1e-04
4	GTEx	Brain Cortex	0.1650	0.0720	8.5e-03	0.181	NA	0.053	NA	0.082	1.0e-05	NA	1.4e-02	NA	2.8e-03
5	GTEx	Brain Frontal Cortex BA9	0.2436	0.0847	1.4e-03	0.159	NA	0.102	NA	0.123	5.2e-05	NA	1.2e-03	NA	3.9e-04
6	GTEx	Brain Nucleus accumbens basal ganglia	0.1850	0.0760	4.6e-03	0.175	NA	0.087	NA	0.145	1.9e-05	NA	2.4e-03	NA	1.1e-04
7	GTEx	Brain Putamen basal ganglia	0.2800	0.1040	3.1e-03	0.219	NA	0.097	NA	0.178	6.4e-06	NA	2.6e-03	NA	5.3e-05
8	GTEx	Breast Mammary Tissue	0.1440	0.0550	3.6e-03	0.080	NA	0.042	NA	0.057	6.5e-05	NA	3.4e-03	NA	7.0e-04
9	GTEx	Breast Mammary Tissue (Female)	0.0644	0.0563	1.6e-01	0.043	NA	-0.008	NA	0.014	2.0e-02	NA	6.3e-01	NA	1.2e-01
10	GTEx	Prostate	0.4950	0.1200	2.4e-03	-0.012	NA	0.039	NA	0.000	8.9e-01	NA	3.8e-02	NA	3.3e-01
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1860	0.0480	3.5e-07	0.186	NA	0.195	NA	0.196	1.8e-10	NA	6.4e-11	NA	5.5e-11
12	GTEx	Skin Sun Exposed Lower leg	0.1590	0.0400	2.7e-08	0.141	NA	0.144	NA	0.152	1.0e-11	NA	5.9e-12	NA	1.3e-12
13	GTEx	Small Intestine Terminal Ileum	0.4550	0.1260	1.3e-03	-0.006	NA	-0.013	NA	0.004	4.7e-01	NA	9.5e-01	NA	2.6e-01
14	ROSMAP	Brain Pre-frontal Cortex	0.3148	0.0386	0.0e+00	0.497	0.453	0.498	0.492	0.498	2.1e-73	1.1e-64	1.3e-73	2.5e-72	1.3e-73
15	TCGA	Breast Invasive Carcinoma	0.0348	0.0139	5.3e-11	0.055	0.061	0.058	NA	0.057	2.1e-11	1.9e-12	5.3e-12	NA	1.0e-11
16	TCGA	Glioblastoma Multiforme	0.2020	0.0850	4.5e-06	0.235	0.190	0.175	NA	0.202	9.6e-08	2.0e-06	5.2e-06	NA	9.1e-07
17	TCGA	Brain Lower Grade Glioma	0.1446	0.0500	0.0e+00	0.202	0.173	0.191	NA	0.185	1.9e-22	2.9e-19	3.0e-21	NA	1.5e-20

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Sitting height	8.9	63.4	97.2	8.9	8.8	8.6	8.8	9.6	7.5	9.9	0.6	-1.9	5.1	8.2	8.2	7.6	9.2	6.9	9.0	9.4
Average weekly champagne plus white wine intake	7.7	10.5	15.9	3.7	3.6	3.5	3.6	4.0	3.5	4.0	0.6	0.0	0.9	3.5	3.4	2.9	3.6	3.2	3.7	3.5
Alcohol drinker status: Previous	7.3	8.3	12.0	-3.1	-3.2	-3.2	-3.2	-3.1	-2.5	-3.2	-1.9	-1.8	-2.7	-3.3	-3.5	-0.4	-3.1	-3.1	-3.3	-3.0
Average weekly spirits intake	6.8	8.4	11.3	3.3	3.2	3.2	3.2	3.3	3.3	3.4	1.3	-0.3	1.7	3.1	3.2	1.4	3.2	3.0	3.3	3.3
Angina (self-reported)	6.0	7.9	10.0	-3.1	-3.1	-3.1	-3.1	-3.0	-2.7	-3.1	-1.9	2.1	-1.8	-3.1	-3.2	-0.3	-3.0	-3.0	-3.1	-3.0
Height	5.9	112.9	171.6	11.9	11.9	11.7	11.9	12.6	11.0	13.1	3.0	-2.6	6.5	11.2	11.3	6.7	12.3	10.2	12.0	12.3
Father’s age at death	5.8	7.7	11.7	3.1	3.0	3.1	3.0	2.8	3.0	2.9	2.6	0.8	1.4	3.2	3.2	1.1	3.1	3.4	3.1	2.5
Qualifications: A levels/AS levels or equivalent	5.4	11.9	18.7	3.9	3.8	3.8	3.8	4.3	3.0	4.1	1.5	1.8	1.1	3.7	3.8	2.6	4.0	3.0	4.1	3.9
Schizophrenia (2014)	5.2	11.5	27.6	3.1	3.2	2.8	3.2	4.3	2.5	4.4	-4.6	-2.1	3.0	2.3	2.4	5.2	3.2	0.7	3.0	4.3
Medication: Lisinopril	5.2	6.7	10.0	-2.8	-2.8	-2.9	-2.8	-2.5	-2.9	-2.6	-2.0	-2.1	-1.7	-3.0	-2.9	0.3	-2.8	-3.2	-2.8	-2.4
Angina	5.0	6.6	8.3	-2.8	-2.8	-2.9	-2.8	-2.7	-2.5	-2.8	-1.9	2.1	-1.8	-2.9	-2.9	-0.2	-2.7	-2.8	-2.8	-2.7
Standing height	5.0	49.9	78.3	7.9	7.9	7.7	7.9	8.4	7.2	8.8	1.4	-1.5	4.8	7.4	7.4	5.0	8.0	6.8	8.0	8.2
Comparative height size at age 10	4.9	26.9	39.8	5.7	5.7	5.6	5.7	6.0	5.2	6.3	1.2	-2.1	5.0	5.4	5.4	3.5	5.9	4.9	5.8	5.8
Hearing difficulty/problems: Yes	4.6	7.0	9.4	2.9	3.0	3.0	3.0	3.0	3.0	3.1	1.3	0.1	0.4	2.9	2.9	2.3	2.9	2.8	2.9	3.0
Average weekly fortified wine intake	4.2	5.0	6.9	2.4	2.4	2.5	2.4	2.5	2.4	2.3	1.8	0.5	-1.0	2.5	2.6	1.4	2.4	2.5	2.5	2.5
Forced expiratory volume in 1-second (FEV1), predicted	3.9	8.1	11.8	3.1	3.2	3.2	3.2	3.2	2.5	3.3	1.8	0.0	1.9	3.2	3.4	1.4	3.1	2.9	3.2	3.2
Alcohol usually taken with meals	3.8	6.2	10.2	2.9	2.8	2.8	2.8	3.2	2.5	2.8	0.9	0.8	0.5	2.7	2.8	1.9	2.7	2.3	2.9	2.7
Qualifications: College or University degree	3.8	11.9	29.5	3.5	3.6	3.4	3.6	4.1	3.5	4.3	-2.0	-0.1	1.2	3.0	3.5	5.4	3.6	2.4	3.4	4.1
Alcohol intake frequency.	3.8	8.9	13.2	-3.2	-3.2	-3.1	-3.2	-3.3	-3.1	-3.4	-0.2	-1.9	-1.3	-3.0	-3.1	-3.6	-3.3	-3.0	-3.2	-3.3
Arm fat-free mass (right)	3.7	19.1	31.0	4.8	4.8	4.7	4.8	5.5	4.1	5.6	0.9	-1.5	1.9	4.5	4.6	4.2	4.9	4.2	5.0	5.0
Trunk fat-free mass	3.6	20.4	34.3	5.0	5.0	4.9	5.0	5.7	4.3	5.9	0.9	-1.2	2.1	4.6	4.7	3.9	5.1	4.3	5.2	5.3
Trunk predicted mass	3.6	20.4	34.1	5.0	5.0	4.9	5.0	5.7	4.3	5.8	1.0	-1.3	2.2	4.6	4.7	3.8	5.1	4.3	5.2	5.2
Ever had prostate specific antigen (PSA) test	3.5	4.0	6.1	2.4	2.3	2.3	2.3	2.5	2.2	2.3	0.8	-0.4	0.3	2.3	1.8	1.3	2.3	1.9	2.3	2.2
Gout (self-reported)	3.4	4.7	7.6	2.6	2.4	2.3	2.4	2.8	2.0	2.5	0.7	0.5	0.7	2.3	1.9	2.3	2.6	1.9	2.6	2.5
Whole body fat-free mass	3.4	19.5	32.8	4.9	4.8	4.7	4.8	5.6	4.1	5.7	0.9	-1.1	1.7	4.5	4.6	4.1	5.0	4.1	5.1	5.2
Arm fat-free mass (left)	3.4	17.3	28.8	4.6	4.5	4.4	4.5	5.2	3.8	5.4	0.4	-1.9	1.9	4.2	4.3	3.8	4.7	3.8	4.7	4.9
Arm predicted mass (right)	3.3	16.7	27.7	4.5	4.5	4.4	4.5	5.1	3.8	5.3	0.8	-1.3	1.8	4.2	4.2	4.0	4.6	3.8	4.7	4.7
Bipolar Disorder or Schizophrenia	3.2	7.8	25.2	2.4	2.4	2.0	2.4	3.5	1.7	3.5	-4.7	-1.6	2.9	1.5	1.6	5.0	2.4	-0.0	2.2	3.4
Neck or shoulder pain in last month	3.2	4.6	6.9	-2.3	-2.4	-2.4	-2.4	-2.6	-2.0	-2.6	-1.1	-2.3	0.1	-2.3	-2.1	-1.2	-2.3	-2.0	-2.4	-2.3
Whole body water mass	3.2	18.4	31.4	4.8	4.7	4.6	4.7	5.5	3.9	5.6	0.6	-1.1	1.7	4.3	4.4	4.1	4.8	3.9	5.0	5.0
Schizophrenia (2018)	3.1	6.4	14.5	2.3	2.4	2.0	2.4	3.2	1.7	3.3	-3.8	-1.6	2.7	1.6	1.8	3.6	2.4	0.3	2.2	3.2
Mother’s age at death	3.1	3.8	5.6	2.2	2.2	2.2	2.2	2.3	1.5	2.3	1.2	0.4	0.1	2.3	2.0	1.4	2.4	2.0	2.3	2.1
Supplements: Vitamin C	3.0	3.6	5.2	2.1	2.1	2.1	2.1	2.0	2.3	2.1	0.8	1.4	-0.3	2.1	2.2	1.2	1.9	2.1	2.0	2.2
Basal metabolic rate	3.0	16.5	28.0	4.5	4.5	4.3	4.5	5.2	3.7	5.3	0.6	-1.2	1.3	4.1	4.2	4.0	4.6	3.6	4.7	4.8
Coronary Artery Disease (CAD)	2.9	3.4	5.2	-1.8	-2.0	-2.1	-2.0	-1.8	-1.8	-2.0	-2.2	-0.3	-0.6	-2.3	-2.3	1.1	-2.0	-2.2	-2.0	-1.6
Noisy workplace	2.9	3.6	6.2	-2.0	-2.1	-2.1	-2.1	-1.9	-2.5	-2.2	-0.6	0.6	-1.0	-2.0	-2.2	-0.8	-2.1	-2.0	-2.0	-2.2
Arm predicted mass (left)	2.9	14.5	24.4	4.2	4.1	4.0	4.1	4.8	3.5	4.9	0.4	-1.9	1.5	3.8	4.0	3.7	4.3	3.5	4.3	4.5
Leg fat-free mass (right)	2.8	15.1	25.4	4.3	4.3	4.2	4.3	5.0	3.5	5.0	0.9	-0.6	0.6	4.0	4.1	3.8	4.3	3.5	4.5	4.6
Leg predicted mass (right)	2.8	15.1	25.5	4.3	4.3	4.2	4.3	5.0	3.5	5.0	0.9	-0.6	0.6	4.0	4.1	3.8	4.4	3.5	4.5	4.6
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.2	6.2	-2.2	-2.2	-2.2	-2.2	-2.5	-2.0	-2.2	-0.8	-1.5	1.3	-2.1	-2.1	-2.0	-2.4	-2.0	-2.3	-2.1
Pulse rate, automated reading	2.4	7.7	12.2	3.0	2.9	2.8	2.9	3.5	2.3	3.5	0.3	-2.8	2.4	2.7	2.9	2.1	3.2	2.1	3.0	3.1
Ever had bowel cancer screening	2.4	2.8	4.2	1.9	1.9	1.9	1.9	2.0	1.6	1.9	1.4	0.5	-0.7	2.0	1.8	0.2	1.9	1.7	1.9	1.9
Qualifications: nursing, teaching	2.4	3.7	5.1	2.1	2.1	2.1	2.1	2.2	2.2	2.3	0.1	1.2	-0.1	2.0	1.9	2.3	2.1	1.7	2.1	2.2
Leg fat-free mass (left)	2.3	12.3	21.8	3.9	3.8	3.7	3.8	4.7	3.0	4.7	0.4	-0.5	0.8	3.5	3.5	3.8	4.0	3.0	4.1	4.2
Hearing difficulty/problems with background noise	2.3	3.6	5.4	2.1	2.2	2.2	2.2	2.0	2.2	2.3	0.7	0.3	0.6	2.1	2.0	1.6	2.2	1.9	2.0	2.2
Diabetes diagnosed by doctor	2.3	3.7	5.5	-2.1	-2.2	-2.2	-2.2	-2.3	-2.1	-2.3	-0.7	1.6	-0.8	-2.2	-2.2	-1.0	-1.9	-1.8	-2.2	-2.0
Leg predicted mass (left)	2.2	11.7	20.8	3.8	3.7	3.6	3.7	4.6	2.9	4.5	0.4	-0.4	0.8	3.4	3.4	3.7	3.9	2.9	4.0	4.1
Medication: Omeprazole	2.2	2.6	3.1	-1.7	-1.8	-1.8	-1.8	-1.7	-1.4	-1.7	-0.8	-1.6	-1.5	-1.7	-1.7	-1.3	-1.7	-1.6	-1.8	-1.6
Medication: Metformin	2.1	2.9	4.5	-1.8	-1.9	-1.9	-1.9	-2.0	-2.0	-1.9	-1.1	1.5	0.3	-2.0	-2.1	-0.5	-1.6	-1.8	-1.9	-1.7
Pain all over the body in last month	2.1	2.3	4.1	-1.5	-1.6	-1.6	-1.6	-1.3	-1.8	-1.5	-1.9	0.7	0.5	-1.7	-1.5	-1.3	-1.5	-2.0	-1.5	-1.5
Alcohol intake versus 10 years previously	2.1	3.1	4.0	-2.0	-1.9	-1.9	-1.9	-2.0	-2.0	-1.9	0.2	1.7	-0.3	-1.8	-2.0	-1.8	-1.6	-1.7	-2.0	-1.9
Hair/balding pattern: Pattern 3	2.1	3.2	4.0	1.7	1.9	1.9	1.9	1.9	1.9	1.8	0.9	-1.2	-1.2	2.0	2.0	1.9	1.8	2.0	1.8	1.9
Commuting to job workplace: Public transport	2.1	2.5	3.9	1.7	1.8	1.8	1.8	1.8	1.8	1.9	1.3	0.5	-0.8	1.9	1.6	0.5	1.6	2.0	1.8	1.5
Prostate Cancer	2.0	2.7	4.6	1.9	1.8	1.8	1.8	2.1	1.3	1.9	0.6	0.6	1.2	1.8	1.8	1.2	2.1	1.3	1.9	2.0
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.3	4.7	-2.0	-1.9	-1.9	-1.9	-2.1	-2.2	-2.1	-0.4	-1.2	0.4	-1.9	-1.9	-1.7	-1.9	-1.9	-2.1	-2.0
High blood pressure (siblings)	2.0	2.8	4.4	2.0	2.0	2.0	2.0	1.9	1.5	1.9	0.9	0.2	0.1	1.9	2.1	0.9	2.0	1.6	2.0	1.8
Medication: Seretide 50 evohaler	2.0	2.3	4.4	1.6	1.5	1.5	1.5	1.4	1.4	1.4	1.6	2.1	1.2	1.6	1.6	-0.7	1.6	1.6	1.6	1.3
Illnesses of father: Heart disease	2.0	2.7	7.2	-1.6	-1.5	-1.7	-1.5	-1.2	-1.6	-1.3	-2.7	0.6	0.7	-1.8	-2.1	1.5	-1.6	-2.3	-1.7	-1.2
Bipolar Disorder (2011)	1.9	1.9	3.8	1.4	1.4	1.2	1.4	1.9	0.9	1.9	-1.3	0.0	1.2	1.1	0.9	1.7	1.7	0.7	1.4	1.7
Headache pain in last month	1.9	3.2	4.7	2.2	2.1	2.1	2.1	2.0	1.7	1.8	1.4	-0.0	0.4	2.1	2.0	-0.1	2.1	1.8	2.1	1.9
Worry too long after embarrassment	1.9	3.1	6.2	1.8	1.9	2.0	1.9	1.3	1.9	1.5	2.5	0.9	-0.7	2.2	2.1	-0.6	1.6	2.3	1.8	1.6
Number of full sisters	1.9	2.4	7.0	-1.3	-1.4	-1.5	-1.4	-1.3	-1.2	-1.4	-2.7	-0.7	2.1	-1.7	-1.4	-0.7	-1.5	-2.0	-1.5	-1.2
Qualifications: None of the above	1.8	4.0	5.3	-2.2	-2.1	-2.1	-2.1	-2.2	-2.0	-2.3	-1.0	-0.5	-1.6	-2.1	-2.2	-1.7	-2.1	-2.0	-2.3	-2.1
Chest pain or discomfort	1.8	2.6	5.7	1.6	1.7	1.7	1.7	1.4	1.9	1.7	0.7	2.4	0.4	1.7	1.7	1.1	1.6	1.8	1.5	1.8
Intelligence (Savage-Jansen 2018)	1.7	5.3	9.0	2.6	2.5	2.5	2.5	3.0	2.0	3.0	1.1	0.1	0.8	2.5	2.3	1.9	2.7	1.9	2.7	2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.6	6.2	-2.0	-2.0	-1.9	-2.0	-2.3	-2.0	-2.5	-0.1	-0.0	-1.6	-1.8	-1.8	-2.0	-2.1	-1.7	-1.9	-2.3
Fractured/broken bones in last 5 years	1.7	2.2	3.5	-1.7	-1.7	-1.6	-1.7	-1.5	-1.6	-1.7	-0.2	-0.3	-1.9	-1.6	-1.6	0.1	-1.6	-1.5	-1.6	-1.6
Myopia	1.7	2.5	16.6	-1.0	-1.0	-1.0	-1.0	-1.0	-0.8	-1.0	0.0	4.1	-1.2	-1.0	-0.9	-3.4	-1.0	-0.8	-1.0	-1.1
Type 2 Diabetes (T2D) (2018)	1.6	3.0	4.9	-1.9	-2.0	-1.9	-2.0	-2.2	-1.6	-2.1	-0.7	-0.0	-0.5	-2.0	-1.9	-1.5	-1.9	-1.6	-2.0	-1.7
Chronotype (morning person)	1.6	3.8	9.7	-2.0	-2.0	-1.9	-2.0	-2.5	-1.4	-2.6	1.5	0.1	0.4	-1.6	-2.0	-3.1	-2.1	-0.8	-2.0	-2.5
Diabetes (self-reported)	1.6	2.5	4.3	-1.6	-1.7	-1.6	-1.7	-2.1	-1.6	-2.0	0.7	1.9	-1.1	-1.5	-1.7	-1.3	-1.4	-0.9	-1.6	-1.7
Weight	1.6	7.9	14.0	3.1	3.1	3.0	3.1	3.7	2.4	3.7	0.4	-1.4	0.4	2.8	2.8	2.7	3.3	2.4	3.2	3.4
Medication: Allopurinol	1.6	2.1	4.0	1.7	1.5	1.4	1.5	2.0	0.5	1.7	0.1	-1.2	2.0	1.4	1.1	1.5	1.6	0.8	1.7	1.5
Miserableness	1.6	2.7	4.0	1.8	1.9	1.9	1.9	1.7	1.2	1.9	1.0	0.0	1.0	2.0	1.9	1.1	1.8	1.6	1.8	2.0
Tinnitus: Yes, now most or all of the time	1.6	1.8	3.7	1.4	1.4	1.5	1.4	1.3	1.9	1.4	1.3	-0.0	-1.2	1.5	1.3	0.0	1.4	1.5	1.4	1.3
Unable to work because of sickness or disability	1.6	2.1	2.9	-1.5	-1.5	-1.6	-1.5	-1.5	-1.6	-1.7	-0.4	0.5	1.1	-1.5	-1.4	-1.6	-1.6	-1.6	-1.6	-1.5
Lung FVC	1.5	7.5	10.8	-3.1	-2.9	-3.0	-2.9	-3.1	-2.8	-3.1	-2.5	-0.1	-0.8	-3.0	-3.1	-0.5	-3.3	-3.1	-3.1	-2.9
Neuroticism	1.5	3.7	5.6	2.1	2.1	2.1	2.1	1.7	2.2	2.0	1.3	2.0	0.7	2.3	2.2	0.0	2.1	2.4	2.0	2.0
Mean Putamen Volume	1.4	1.6	2.4	-1.3	-1.5	-1.6	-1.5	-1.5	-1.0	-1.4	-0.9	0.4	-1.1	-1.6	-1.6	0.3	-1.5	-1.1	-1.4	-1.2
Smoking Status	1.4	3.3	9.7	1.9	1.9	1.8	1.9	2.1	1.9	2.0	-0.0	0.3	1.0	1.7	1.6	3.1	1.8	1.3	1.8	2.3
Sensitivity / hurt feelings	1.4	2.4	5.0	1.7	1.7	1.8	1.7	1.4	1.8	1.4	1.4	0.6	0.1	1.9	1.7	-0.1	1.6	2.2	1.7	1.5
Pack years adult smoking proportion	1.4	2.1	3.6	-1.6	-1.5	-1.5	-1.5	-1.7	-1.3	-1.4	-0.6	-1.5	0.1	-1.5	-1.6	-1.9	-1.7	-1.3	-1.7	-1.3
Mean time to correctly identify matches	1.4	2.6	24.5	-0.3	-0.3	-0.6	-0.3	0.6	-0.3	0.5	-5.0	-2.0	0.0	-1.1	-0.9	3.0	-0.3	-1.7	-0.4	0.6
Smoking status: Current	1.4	2.2	4.3	1.6	1.6	1.5	1.6	1.3	2.1	1.4	1.1	0.8	1.5	1.5	1.6	1.0	1.3	1.8	1.4	1.6
Pain type(s) experienced in last month: Hip pain	1.4	1.8	5.3	-1.4	-1.3	-1.3	-1.3	-1.6	-0.8	-1.4	-1.0	-2.3	-0.0	-1.4	-1.4	-0.6	-1.4	-1.1	-1.5	-1.2
Bipolar Disorder (2018)	1.3	2.0	12.5	0.9	0.8	0.6	0.8	1.6	0.6	1.4	-2.8	-0.6	1.1	0.4	0.5	3.5	0.8	-0.4	0.8	1.5
Type 2 Diabetes (T2D) (2012)	1.3	1.5	2.8	-1.0	-1.5	-1.5	-1.5	-1.2	-1.2	-1.4	-1.5	-1.0	0.2	-1.7	-1.5	0.4	-0.9	-1.2	-1.2	-0.9
Diabetes (mother)	1.3	1.7	2.9	-1.4	-1.3	-1.3	-1.3	-1.5	-1.6	-1.4	0.2	-1.7	-0.5	-1.1	-1.6	-0.8	-1.4	-1.2	-1.4	-1.3
Townsend deprivation index at recruitment	1.3	1.8	3.3	-1.4	-1.4	-1.5	-1.4	-1.5	-1.4	-1.5	-1.1	-0.7	0.8	-1.4	-1.5	-0.5	-1.5	-1.8	-1.6	-1.1
Maternal smoking around birth	1.3	1.8	2.8	1.5	1.5	1.5	1.5	1.5	1.7	1.4	0.3	1.6	0.6	1.3	1.5	0.8	1.2	1.4	1.5	1.4
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	6.4	1.8	1.8	1.6	1.8	1.8	1.9	2.0	-1.8	0.6	2.5	1.3	1.4	2.1	1.7	1.3	1.6	1.9
Exposure to tobacco smoke outside home	1.3	1.8	3.4	1.4	1.5	1.5	1.5	1.1	1.8	1.4	0.5	0.6	1.2	1.4	1.3	0.8	1.5	1.6	1.3	1.4
Wears glasses or contact lenses	1.3	1.6	2.5	1.5	1.4	1.4	1.4	1.3	1.6	1.4	0.2	1.2	0.4	1.3	0.8	0.2	1.4	1.5	1.4	1.3
Ever smoked	1.3	2.4	6.1	1.5	1.5	1.4	1.5	1.7	1.5	1.9	-0.8	-0.9	1.2	1.3	1.3	2.5	1.7	1.0	1.4	1.9
Reaction Time	1.2	2.3	20.4	-0.6	-0.5	-0.8	-0.5	0.2	-0.9	0.2	-4.5	-1.5	0.7	-1.3	-1.0	2.5	-0.5	-1.9	-0.7	0.3
Age at First Birth	1.2	1.8	3.7	1.4	1.4	1.4	1.4	1.4	1.3	1.6	0.9	0.1	0.1	1.4	1.6	1.9	1.6	1.2	1.3	1.3
Past tobacco smoking	1.2	2.1	9.2	-1.3	-1.3	-1.1	-1.3	-1.9	-0.9	-1.8	1.6	1.0	-0.7	-1.0	-1.1	-3.0	-1.5	-0.3	-1.3	-1.8
Happiness	1.2	1.5	2.3	-1.4	-1.3	-1.3	-1.3	-1.5	-1.3	-1.2	-0.3	0.3	-0.8	-1.2	-1.2	-1.5	-1.4	-1.3	-1.5	-1.2
Comparative body size at age 10	1.2	3.4	5.1	-1.9	-2.0	-2.1	-2.0	-1.9	-1.8	-1.9	-2.2	-1.1	0.6	-2.2	-2.0	0.3	-1.7	-2.2	-1.9	-1.9
Wheeze or whistling in the chest in last year	1.2	2.2	4.3	1.7	1.6	1.5	1.6	2.1	1.5	1.8	-0.3	0.7	1.1	1.4	1.3	1.6	1.7	0.9	1.7	1.8
Illnesses of siblings: Diabetes	1.2	1.5	5.6	0.9	0.9	0.8	0.9	1.1	1.6	1.2	-2.0	-1.9	-0.3	0.6	0.4	2.4	0.9	0.5	0.7	1.3
Pack years of smoking	1.2	1.7	2.5	-1.5	-1.4	-1.4	-1.4	-1.4	-1.3	-1.2	-0.6	-1.4	-0.3	-1.4	-1.5	-1.6	-1.5	-1.3	-1.5	-1.2
Hand grip strength (right)	1.1	2.9	5.5	1.9	1.8	1.8	1.8	2.1	1.4	2.1	0.4	1.1	0.8	1.7	1.9	2.4	1.8	1.5	2.0	1.7
Serious illness, injury or assault to yourself	1.1	1.3	3.8	-1.1	-1.1	-1.2	-1.1	-1.0	-1.4	-0.8	-1.9	0.0	-0.2	-1.3	-1.4	0.7	-1.3	-1.4	-1.1	-0.8
Illnesses of siblings	1.1	1.5	3.5	-1.4	-1.3	-1.2	-1.3	-1.5	-1.1	-1.4	0.6	0.5	0.5	-1.1	-1.2	-1.9	-1.3	-0.7	-1.2	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	3.4	1.2	1.1	1.2	1.1	0.8	1.4	0.9	1.8	-1.0	-0.8	1.3	1.1	-0.0	1.2	1.7	1.2	0.9
Eye problems/disorders: Cataract	1.1	1.3	2.4	-0.9	-1.2	-1.2	-1.2	-0.8	-1.1	-1.2	-1.5	-0.8	1.6	-1.3	-1.3	-0.9	-1.2	-1.3	-0.9	-1.0
Commuting to job workplace: Cycle	1.1	1.4	10.8	0.6	0.6	0.5	0.6	1.2	0.4	1.2	-1.8	1.1	1.1	0.2	0.0	3.3	0.5	-0.6	0.6	1.0
Depression (Nagel 2018)	1.0	1.5	3.7	-1.3	-1.0	-1.0	-1.0	-1.4	-1.2	-1.2	-0.4	-0.9	1.8	-1.0	-1.1	-1.9	-1.2	-0.8	-1.3	-1.2
Neuroticism (Nagel 2018)	1.0	2.4	4.2	1.6	1.8	1.8	1.8	1.3	1.7	1.7	1.1	1.2	0.0	1.9	1.8	-0.9	1.6	2.1	1.6	1.5
Hair Pigment	1.0	27.8	38.6	5.9	6.0	6.0	6.0	6.2	5.8	6.2	2.4	-1.8	0.6	5.9	6.0	2.4	6.1	5.1	5.9	5.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.7	-1.1	-1.0	-1.0	-1.0	-1.3	-0.9	-1.1	-0.8	-1.7	1.3	-1.0	-1.2	-1.5	-1.1	-0.8	-1.2	-0.9
Hip circumference	1.0	4.4	8.4	2.3	2.2	2.2	2.2	2.9	1.6	2.9	-0.3	-1.2	0.1	1.9	2.0	2.4	2.4	1.5	2.4	2.5
Length of working week for main job	1.0	1.1	2.0	-1.2	-1.1	-1.1	-1.1	-1.4	-1.1	-1.4	0.3	-0.2	-0.2	-1.0	-1.1	-1.3	-1.1	-0.8	-1.2	-1.2
Birth weight of first child	1.0	1.8	3.3	1.4	1.4	1.5	1.4	1.2	1.0	1.2	1.8	-0.6	0.1	1.6	1.8	0.5	1.4	1.7	1.5	1.2
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	7.2	1.3	1.2	1.3	1.2	1.2	0.4	1.0	2.7	1.3	0.3	1.4	1.5	0.4	1.3	1.1	1.5	0.9
Blood clot in the leg (DVT)	1.0	1.3	9.1	0.7	0.6	0.7	0.6	0.2	0.8	0.3	2.3	-0.1	-0.7	0.9	0.9	-3.0	0.5	1.4	0.8	0.2
Breast cancer (self-reported)	1.0	1.2	6.1	-0.8	-0.9	-1.1	-0.9	-0.6	-0.1	-0.5	-2.5	-0.9	0.5	-1.4	-1.5	1.1	-1.0	-1.2	-1.0	-0.5
Hearing aid user	1.0	1.1	1.8	1.1	1.2	1.2	1.2	1.4	0.4	1.1	1.1	0.8	-0.8	1.2	1.3	-0.8	1.2	0.7	1.2	0.9
Financial situation satisfaction	1.0	1.3	3.9	-1.1	-1.0	-1.0	-1.0	-1.5	-0.6	-1.4	0.3	-1.5	-0.6	-0.9	-0.7	-2.0	-1.2	-0.7	-1.2	-1.0
Age started oral contraceptive pill	1.0	1.3	8.6	0.9	0.9	0.8	0.9	1.4	0.8	1.3	-1.2	0.5	-0.5	0.6	0.6	2.9	0.9	0.4	1.0	1.2
Alzheimer’s Disease (in father)	0.9	0.9	2.0	-1.0	-1.1	-1.0	-1.1	-1.3	-0.4	-1.1	-0.1	-0.8	0.2	-1.0	-1.4	0.9	-1.0	-0.3	-1.1	-1.3
Crohns Disease (2012)	0.9	1.5	2.6	-1.2	-1.3	-1.4	-1.3	-1.2	-0.9	-1.4	-1.6	0.0	-1.0	-1.4	-1.6	0.7	-1.4	-1.1	-1.3	-1.0
Lupus	0.9	1.3	4.3	1.2	1.1	1.1	1.1	1.6	0.6	1.4	-0.1	0.1	1.3	1.1	1.0	2.1	1.1	0.6	1.4	1.1
Heel T-Score	0.9	7.1	51.1	-0.8	-0.8	-1.3	-0.8	-0.2	-1.1	0.1	-7.2	-1.6	4.7	-1.9	-1.5	5.1	-0.7	-2.5	-1.1	0.0
Impedance of leg (right)	0.9	4.1	7.3	-2.1	-2.0	-2.1	-2.0	-2.7	-1.5	-2.4	-1.4	-1.4	2.0	-2.1	-2.1	-1.7	-2.0	-1.9	-2.4	-2.2
Neuroticism score	0.9	1.9	2.8	1.5	1.5	1.6	1.5	1.3	1.5	1.4	1.0	1.1	-0.0	1.7	1.6	-0.2	1.5	1.6	1.5	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	2.3	-1.2	-1.1	-1.2	-1.1	-1.2	-1.2	-1.3	-1.0	0.6	0.1	-1.2	-1.1	-1.4	-1.3	-1.5	-1.4	-1.0
Commuting to job workplace: Walk	0.9	0.9	1.8	1.1	1.0	1.1	1.0	0.9	0.8	0.9	0.8	0.6	-0.5	1.1	1.2	0.7	1.3	1.1	1.1	0.9
Medication: Atorvastatin	0.9	1.1	2.6	-1.0	-1.0	-1.1	-1.0	-0.7	-1.6	-1.0	-0.7	0.5	-0.8	-1.1	-1.1	1.1	-0.9	-1.6	-1.0	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	9.1	0.5	0.4	0.5	0.4	-0.0	0.7	0.1	2.2	-0.1	-0.8	0.7	0.7	-3.0	0.3	1.3	0.6	-0.0
Alzheimer’s Disease (in mother)	0.8	0.9	2.1	1.0	1.0	1.0	1.0	1.0	1.2	1.1	0.2	0.1	-1.4	1.0	0.9	0.2	1.0	1.2	1.0	0.7
Blood Eosinophil Count	0.8	6.5	11.0	2.9	2.7	2.6	2.7	3.3	2.6	3.3	0.7	0.5	-0.6	2.6	3.1	1.8	3.3	2.2	2.9	2.8
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.6	-0.9	-0.8	-0.8	-0.8	-1.2	-0.7	-1.0	0.2	-1.4	1.5	-0.7	-0.8	-1.9	-1.0	-0.5	-1.0	-0.9
Medication: Atenolol	0.8	1.0	1.6	-1.2	-1.0	-1.1	-1.0	-1.1	-0.4	-1.0	-0.8	0.8	-1.2	-1.0	-1.3	-0.2	-1.2	-0.9	-1.3	-0.8
Had other major operations	0.8	0.9	2.5	1.0	0.9	0.9	0.9	1.0	0.9	1.0	1.6	0.0	0.0	1.0	0.8	1.2	1.0	1.1	1.1	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	5.3	1.3	1.3	1.2	1.3	1.3	1.2	1.5	-1.2	0.7	2.3	1.0	0.9	1.9	1.2	1.0	1.2	1.4
Arm fat percentage (right)	0.8	3.2	5.2	-1.9	-1.9	-1.9	-1.9	-1.5	-2.0	-1.8	-1.6	-0.9	-2.3	-2.1	-1.9	-0.3	-1.7	-2.2	-1.9	-1.6
Pulse wave Arterial Stiffness index	0.8	1.0	7.6	0.3	0.1	-0.0	0.1	0.8	-0.1	0.6	-1.8	-2.8	1.0	-0.2	-0.5	1.5	0.3	-0.8	0.3	0.2
Ever highly irritable/argumentative for 2 days	0.8	1.0	4.0	0.8	0.9	0.8	0.9	1.2	0.9	1.4	-1.3	-0.7	0.4	0.7	0.8	2.0	0.9	0.2	0.8	1.2
Eye problems/disorders: None of the above	0.8	0.9	8.9	-0.8	-0.6	-0.6	-0.6	-0.7	-0.5	-0.5	0.1	0.9	-3.0	-0.6	-0.4	0.6	-0.8	-0.4	-0.8	-0.5
Eye problems/disorders: Glaucoma	0.8	1.0	3.4	0.5	0.5	0.7	0.5	0.1	0.5	0.2	1.7	-1.6	1.9	0.8	0.8	-1.6	0.7	1.1	0.6	0.2
Medication: Bendroflumethiazide	0.8	1.2	10.2	-0.8	-0.9	-0.8	-0.9	-0.9	-0.4	-0.8	-0.1	-1.0	-3.2	-0.8	-1.2	0.8	-1.0	-0.4	-0.8	-0.7
Worry (Nagel 2018)	0.7	1.5	2.7	1.2	1.2	1.2	1.2	1.1	1.4	1.3	1.3	1.3	-1.2	1.4	1.3	-0.5	1.0	1.6	1.2	1.0
Major Depression (MDD)	0.7	0.8	5.1	-0.8	-0.8	-0.8	-0.8	-0.9	-0.8	-0.9	0.1	0.0	2.3	-0.7	-0.9	0.0	-0.8	-0.7	-0.9	-1.0
Neuroticism (2016)	0.7	1.0	3.5	0.7	0.8	0.9	0.8	0.4	0.8	0.6	1.5	0.9	1.8	1.1	1.0	-1.9	0.6	1.1	0.7	0.5
Blood Red Count	0.7	6.9	10.1	3.0	3.0	3.0	3.0	3.1	2.1	2.9	1.7	0.9	-1.0	3.1	3.1	0.3	3.0	2.6	3.2	3.0
Heart attack	0.7	0.9	3.0	-0.9	-0.8	-0.9	-0.8	-0.7	-0.9	-0.7	-1.7	-0.8	-0.6	-1.0	-1.0	0.2	-0.8	-1.2	-1.0	-0.7
Impedance of arm (right)	0.7	3.1	4.6	-1.9	-1.8	-1.9	-1.8	-2.0	-1.6	-2.0	-1.6	0.4	0.8	-1.9	-1.8	-1.6	-1.9	-2.1	-2.0	-1.8
Pulse rate	0.7	1.2	2.1	1.1	1.2	1.2	1.2	1.3	0.7	1.4	-0.8	-1.2	0.6	1.0	1.2	0.8	1.2	0.7	1.1	1.3
Depression (self-reported)	0.7	0.9	1.5	-1.0	-1.0	-1.0	-1.0	-1.0	-0.9	-1.0	-0.4	0.0	-0.3	-1.0	-1.2	-0.8	-1.0	-0.9	-1.1	-1.1
Exposure to tobacco smoke at home	0.7	0.7	6.0	-0.5	-0.5	-0.7	-0.5	-0.3	-0.2	-0.4	-2.4	-0.8	1.1	-0.8	-0.6	0.6	-0.5	-1.1	-0.7	-0.1
Number of children fathered	0.7	0.8	4.2	0.7	0.6	0.6	0.6	1.0	-0.1	0.8	-0.5	1.8	2.0	0.5	0.7	0.8	0.9	-0.1	0.8	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.2	-0.6	-0.6	-0.4	-0.6	-1.1	-0.3	-1.0	1.7	0.4	-1.8	-0.3	-0.3	-1.4	-0.5	0.5	-0.6	-0.8
Age at first live birth	0.7	1.3	9.1	0.8	0.7	0.6	0.7	1.3	0.4	1.3	-1.4	0.1	-1.4	0.4	0.6	3.0	1.0	0.1	0.9	1.1
Pulse wave peak to peak time	0.7	0.9	5.9	0.3	0.4	0.6	0.4	-0.1	0.5	0.1	1.7	2.4	-0.6	0.7	1.0	-1.1	0.3	1.1	0.3	0.4
Mouth/teeth dental problems: Loose teeth	0.7	0.9	2.5	1.0	0.9	0.8	0.9	1.2	0.4	1.0	-0.2	-1.6	-0.4	0.7	0.9	1.3	1.0	0.3	1.1	1.0
Migraine (self-reported)	0.7	0.8	6.2	0.4	0.3	0.5	0.3	-0.0	0.1	-0.1	2.1	0.7	-0.5	0.8	0.6	-2.5	0.2	0.9	0.5	-0.1
Suffer from ‘nerves’	0.7	1.0	3.8	1.0	0.9	0.9	0.9	1.0	1.1	1.2	0.1	0.1	-2.0	0.9	1.1	0.5	1.1	0.9	1.0	1.1
Verbal and Numeric Reasoning (VNR)	0.6	1.4	2.6	1.3	1.2	1.2	1.2	1.4	1.1	1.5	0.5	-0.1	0.5	1.2	1.1	1.3	1.6	0.9	1.3	1.4
Respiratory disease	0.6	1.2	2.4	1.2	1.1	1.0	1.1	1.4	0.9	1.6	-0.6	1.0	0.9	0.9	1.0	1.5	1.3	0.7	1.2	1.1
Hand grip strength (left)	0.6	1.7	2.5	1.4	1.4	1.4	1.4	1.4	1.6	1.6	0.2	0.7	-0.4	1.3	1.5	1.5	1.3	1.5	1.4	1.4
Medication: Co-codamol	0.6	0.7	4.7	-0.5	-0.6	-0.7	-0.6	-0.4	-0.7	-0.6	-1.4	-0.6	-0.2	-0.9	-0.3	2.2	-0.4	-1.0	-0.6	-0.2
Current tobacco smoking	0.6	1.0	2.6	1.0	1.0	1.0	1.0	0.6	1.6	0.7	1.1	0.7	1.3	1.0	1.0	0.4	0.8	1.3	0.8	1.0
Relative age voice broke	0.6	0.9	4.9	0.8	0.7	0.7	0.7	0.8	0.3	0.9	-0.3	-2.2	-1.0	0.6	0.9	1.6	0.8	0.4	0.8	0.8
Trunk fat mass	0.6	2.4	4.3	1.6	1.6	1.5	1.6	2.1	1.2	2.0	-0.6	-1.7	-0.5	1.3	1.3	1.9	1.8	1.0	1.6	1.9
Financial difficulties in last 2 years	0.6	0.8	3.1	-0.8	-0.8	-0.9	-0.8	-0.7	-0.8	-0.7	-0.9	-1.7	-0.1	-1.0	-0.9	0.3	-1.0	-1.1	-0.9	-0.7
Hair/balding pattern: Pattern 4	0.6	1.3	2.2	-1.3	-1.3	-1.3	-1.3	-1.5	-1.0	-1.5	-0.5	0.1	0.4	-1.3	-1.2	-1.0	-1.2	-1.2	-1.3	-1.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	4.1	-0.2	-0.3	-0.5	-0.3	0.3	-0.5	0.1	-2.0	-0.2	1.7	-0.7	-0.7	1.3	-0.3	-1.2	-0.2	0.1
Age at last live birth	0.6	0.8	5.6	-0.4	-0.6	-0.7	-0.6	0.1	-0.8	0.2	-2.4	0.0	-0.5	-0.9	-0.7	1.7	-0.4	-1.3	-0.4	-0.2
Smoking status: Previous	0.6	0.8	6.7	0.2	0.3	0.2	0.3	0.9	-0.2	0.8	-1.7	-1.1	-0.2	0.1	0.1	2.6	0.6	-0.6	0.3	0.8
Arm fat percentage (left)	0.6	2.4	5.2	-1.6	-1.6	-1.7	-1.6	-1.2	-1.8	-1.5	-1.3	-0.7	-2.3	-1.8	-1.7	-0.1	-1.5	-1.9	-1.6	-1.4
Ever taken oral contraceptive pill	0.6	0.7	3.4	-0.8	-0.8	-0.8	-0.8	-0.9	-0.6	-0.8	-0.1	0.6	-1.8	-0.8	-0.6	0.9	-0.9	-0.6	-0.9	-0.6
Basal cell carcinoma (self-reported)	0.6	0.7	2.8	-0.6	-0.5	-0.7	-0.5	-0.3	-0.9	-0.3	-1.7	-0.4	1.4	-0.7	-0.7	0.8	-0.5	-1.3	-0.6	-0.4
Ovarian Cancer	0.5	0.7	2.6	0.8	0.7	0.7	0.7	0.9	0.5	0.9	0.5	-1.6	0.0	0.8	0.7	1.0	0.7	1.0	0.9	0.7
Rheumatoid Arthritis	0.5	0.6	2.7	-0.5	-0.5	-0.4	-0.5	-0.8	-0.9	-1.0	1.3	1.2	0.1	-0.2	-0.3	-1.6	-0.6	0.0	-0.4	-0.9
High blood pressure	0.5	1.4	13.0	0.7	0.6	0.5	0.6	1.0	0.5	1.1	-1.3	-1.4	-1.2	0.4	0.2	3.6	0.6	0.1	0.6	1.2
Chronic bronchitis/emphysema (father)	0.5	0.6	0.9	0.8	0.8	0.8	0.8	0.9	0.1	0.9	0.8	0.5	0.9	0.9	0.6	0.9	0.8	0.5	0.9	0.9
Impedance of leg (left)	0.5	2.2	4.7	-1.5	-1.4	-1.4	-1.4	-2.2	-0.7	-1.8	-0.8	-1.8	1.6	-1.3	-1.2	-1.8	-1.4	-1.0	-1.7	-1.5
Hair/balding pattern: Pattern 2	0.5	0.6	1.6	-0.6	-0.6	-0.7	-0.6	-0.2	-1.2	-0.3	-1.1	0.7	1.0	-0.7	-0.7	-1.1	-0.6	-1.3	-0.5	-0.4
Time employed in main current job	0.5	0.6	3.5	-0.5	-0.6	-0.7	-0.6	-0.2	-0.4	-0.4	-1.9	-0.9	-0.5	-0.8	-0.9	0.2	-0.7	-0.8	-0.6	-0.5
Falls in the last year	0.5	0.7	1.3	-0.9	-0.9	-0.9	-0.9	-0.7	-0.9	-0.8	-0.3	-0.9	0.1	-0.9	-0.9	-0.2	-1.0	-1.1	-0.9	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	6.4	-0.1	-0.3	-0.3	-0.3	-0.1	-0.4	-0.3	-0.3	-2.5	-1.5	-0.3	-0.0	0.6	-0.4	-0.3	-0.1	-0.2
Mouth/teeth dental problems: Dentures	0.5	0.8	2.8	-0.9	-0.8	-0.8	-0.8	-1.2	-0.5	-1.2	0.2	-0.5	-0.2	-0.7	-1.1	-1.7	-1.0	-0.5	-1.0	-0.9
Prospective memory result	0.5	0.7	3.1	0.5	0.4	0.3	0.4	1.0	0.1	0.9	-1.8	-1.6	0.6	0.1	0.2	1.3	0.2	-0.5	0.4	0.7
Peak expiratory flow (PEF)	0.5	1.2	3.3	1.0	1.0	1.1	1.0	0.7	0.8	0.7	1.8	-0.1	-1.5	1.2	1.3	-1.0	1.2	1.3	1.1	0.7
Pulse wave reflection index	0.5	0.6	4.4	0.7	0.6	0.5	0.6	0.9	0.3	0.7	-0.5	-0.5	2.1	0.5	0.4	1.4	0.7	0.2	0.7	0.4
Loud music exposure frequency	0.5	0.6	1.3	0.7	0.7	0.8	0.7	0.7	0.8	0.6	1.0	-0.2	-0.1	0.8	1.1	0.5	0.7	1.1	0.8	0.5
Medication: Paracetamol	0.5	0.8	2.8	-0.8	-0.9	-0.9	-0.9	-0.6	-1.1	-0.9	-0.5	-0.6	-1.7	-1.0	-0.6	-1.0	-0.7	-1.1	-0.8	-0.9
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.0	0.6	0.6	0.5	0.6	0.8	0.7	0.8	-0.9	1.6	1.7	0.3	0.4	0.4	0.6	0.1	0.5	0.5
Leg fat percentage (right)	0.5	1.7	3.9	-1.3	-1.3	-1.4	-1.3	-1.0	-1.6	-1.2	-1.2	-2.0	-0.7	-1.4	-1.5	-0.1	-1.0	-1.7	-1.3	-1.2
Health satisfaction	0.5	0.6	3.9	-0.7	-0.7	-0.7	-0.7	-0.9	-0.5	-0.8	0.2	-0.4	-0.7	-0.7	-0.5	-2.0	-0.8	-0.2	-0.7	-0.8
Whole body fat mass	0.5	1.9	4.3	1.4	1.4	1.3	1.4	1.8	1.1	1.8	-0.7	-1.4	-0.7	1.1	1.1	2.1	1.6	0.8	1.4	1.7
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.6	-0.8	-0.8	-0.8	-0.8	-0.7	-1.0	-0.8	-0.6	-1.3	-0.4	-0.8	-0.7	-0.3	-0.9	-0.8	-0.8	-0.7
Hypertension (Self-reported)	0.5	1.3	11.3	0.7	0.7	0.6	0.7	0.9	0.6	1.0	-1.1	-1.5	-1.3	0.4	0.3	3.4	0.6	0.3	0.6	1.2
Loneliness, isolation	0.5	0.7	2.2	0.7	0.8	0.7	0.8	0.6	1.5	1.0	-1.2	-1.4	0.4	0.6	0.6	-0.1	0.6	0.5	0.5	1.0
Depressed Affect (Nagel 2018)	0.4	0.9	1.3	0.9	1.1	1.1	1.1	0.6	0.9	1.0	0.5	0.3	1.0	1.1	1.1	-0.9	1.0	1.1	0.8	0.9
Body Mass Index (BMI) (2010)	0.4	0.6	3.7	-0.2	-0.2	-0.3	-0.2	0.5	-0.2	0.3	-1.9	0.8	-0.7	-0.5	-0.5	1.7	-0.3	-0.9	-0.1	0.2
HbA1C	0.4	0.4	3.9	-0.4	-0.4	-0.4	-0.4	-0.1	-0.8	-0.5	-0.3	-0.9	2.0	-0.4	-0.1	-0.6	-0.2	-0.3	0.1	-0.5
Blood Platelet Count	0.4	5.0	13.5	-2.0	-2.1	-2.0	-2.1	-2.6	-1.7	-2.6	0.8	0.5	3.3	-1.8	-2.2	-3.7	-2.0	-1.1	-2.1	-2.7
Hypothyroidism (self reported)	0.4	1.0	3.3	1.1	1.0	1.1	1.0	0.9	0.5	0.7	1.8	-0.1	1.0	1.2	1.1	0.4	0.8	1.2	1.1	0.7
Systolic blood pressure, automated reading	0.4	1.3	2.6	1.3	1.2	1.2	1.2	1.6	0.3	1.3	-0.1	-1.2	-0.1	1.2	0.9	1.3	1.3	0.3	1.3	1.5
Supplements: Glucosamine	0.4	0.6	2.0	0.6	0.7	0.7	0.7	0.2	1.1	0.4	0.6	-1.4	1.0	0.7	0.7	0.3	0.6	1.1	0.5	0.4
Waist circumference	0.4	1.6	3.1	1.2	1.2	1.2	1.2	1.8	0.6	1.6	0.6	-1.4	-1.0	1.1	1.0	1.6	1.4	0.7	1.3	1.4
Asthma	0.4	0.8	1.7	-0.8	-1.0	-1.1	-1.0	-0.6	-1.0	-0.6	-1.1	-0.2	1.0	-1.1	-1.1	0.5	-0.8	-1.3	-0.8	-0.9
Medication: Cholesterol lowering	0.4	0.6	1.1	-0.8	-0.9	-0.8	-0.9	-1.0	-0.5	-1.0	0.0	0.2	-0.5	-0.7	-1.0	-0.0	-0.8	-0.6	-0.9	-0.9
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.2	0.7	0.7	0.6	0.7	1.1	0.4	0.9	-0.9	-0.8	-0.1	0.5	0.5	0.8	0.4	-0.0	0.7	0.8
Medication: Amlodipine	0.4	0.6	2.4	-0.5	-0.5	-0.6	-0.5	-0.2	-0.7	-0.3	-1.4	-0.0	-1.1	-0.7	-0.6	1.5	-0.4	-0.9	-0.5	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	3.0	0.5	0.7	0.6	0.7	0.5	0.8	0.7	-1.3	0.3	1.7	0.5	0.4	-0.5	0.5	0.1	0.3	0.9
Emphysema/chronic bronchitis	0.4	0.5	3.9	-0.1	-0.1	-0.2	-0.1	0.2	-0.5	0.2	-2.0	1.4	0.9	-0.4	-0.1	-0.1	-0.2	-0.9	-0.2	0.2
Medication: Ibuprofen	0.4	0.5	3.3	-0.6	-0.5	-0.4	-0.5	-1.0	-0.3	-0.9	1.0	0.6	-0.5	-0.3	-0.3	-1.8	-0.5	-0.1	-0.6	-0.7
Overall health rating	0.4	0.9	1.5	-0.9	-1.0	-1.0	-1.0	-0.7	-1.2	-0.9	-1.2	-0.4	0.6	-1.0	-0.9	-0.8	-0.8	-1.2	-0.9	-0.8
Had major operations	0.4	0.5	2.2	-0.3	-0.3	-0.4	-0.3	0.1	-0.4	0.1	-1.2	0.9	1.4	-0.5	-0.7	1.5	-0.2	-0.7	-0.3	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	3.9	-0.3	-0.3	-0.2	-0.3	-0.5	-0.5	-0.7	1.1	1.1	0.4	-0.0	-0.3	-2.0	-0.4	-0.0	-0.3	-0.4
Knee pain experienced in last month	0.4	0.7	1.9	0.8	0.8	0.8	0.8	1.0	0.3	0.8	-0.1	-1.4	1.3	0.7	0.9	-0.3	1.0	0.4	0.8	0.7
Back pain experienced in last month	0.4	0.5	4.8	0.1	0.1	0.2	0.1	-0.0	0.2	0.1	0.9	-2.2	-0.9	0.2	0.4	-1.4	0.3	0.4	0.2	-0.2
Asthma (self-reported)	0.4	0.8	1.8	-0.8	-0.9	-1.0	-0.9	-0.4	-1.1	-0.5	-1.3	-0.1	0.8	-1.1	-1.1	0.5	-0.7	-1.4	-0.8	-0.8
Alcohol drinker status: Never	0.4	0.5	2.0	-0.5	-0.4	-0.4	-0.4	-0.8	-0.2	-0.7	-0.0	-1.4	-1.4	-0.3	-0.3	-1.2	-0.6	-0.4	-0.6	-0.2
Average weekly beer plus cider intake	0.4	0.5	1.2	-0.7	-0.8	-0.8	-0.8	-0.9	-0.8	-1.0	-0.1	-0.1	0.3	-0.7	-1.1	0.2	-0.8	-0.8	-0.9	-0.4
Vascular/heart problems diagnosed by doctor	0.4	1.0	8.9	0.1	0.2	0.3	0.2	-0.2	0.2	-0.2	1.9	1.2	1.4	0.5	0.7	-3.0	0.3	0.7	0.2	-0.4
Cholesterol lowering medication	0.4	0.7	1.7	-0.8	-0.8	-0.7	-0.8	-1.0	-1.3	-0.9	0.6	-0.3	-1.3	-0.7	-0.7	-0.7	-0.6	-0.3	-0.7	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.4	-0.6	-0.7	-0.7	-0.7	-0.6	-0.6	-0.7	0.5	-0.1	-1.1	-0.6	-0.5	-1.2	-0.7	-0.6	-0.6	-0.7
Supplements: Calcium	0.4	0.4	1.9	-0.4	-0.4	-0.5	-0.4	-0.1	-0.7	-0.1	-1.2	-1.2	-0.4	-0.5	-0.2	1.4	-0.3	-0.8	-0.3	-0.4
HDL Cholesterol	0.3	0.4	3.0	0.3	0.3	0.3	0.3	0.5	0.3	0.5	-0.2	-1.7	-1.5	0.2	0.1	0.8	0.2	0.1	0.3	0.5
LDL Cholesterol	0.3	0.4	3.5	0.3	0.2	0.2	0.2	0.7	-0.1	0.4	0.1	1.9	0.0	0.2	0.2	1.6	0.4	0.1	0.4	0.3
Ulcerative Colitis	0.3	0.4	0.8	-0.8	-0.7	-0.7	-0.7	-0.6	-0.7	-0.7	-0.4	0.5	0.3	-0.7	-0.5	0.7	-0.9	-0.5	-0.6	-0.7
Number of treatments/medications taken	0.3	0.5	2.6	-0.2	-0.3	-0.3	-0.3	0.3	-0.6	-0.0	-0.8	1.2	-1.2	-0.4	-0.3	1.6	-0.1	-0.9	-0.2	-0.0
Relative age of first facial hair	0.3	0.5	4.2	-0.5	-0.5	-0.6	-0.5	-0.4	-0.5	-0.4	-0.4	-2.0	-0.4	-0.6	-0.3	1.3	-0.5	-0.7	-0.5	-0.2
Vitamin and mineral supplements	0.3	0.4	1.3	-0.6	-0.6	-0.6	-0.6	-0.6	-0.6	-0.6	-1.1	-1.1	-0.1	-0.6	-0.6	-0.5	-0.3	-0.7	-0.6	-0.5
Diabetes (father)	0.3	0.3	2.2	0.2	0.2	0.3	0.2	-0.2	0.3	-0.1	1.5	-1.0	-0.6	0.4	0.3	-0.9	0.5	0.4	0.1	0.1
Fed-up feelings	0.3	0.5	1.3	0.7	0.7	0.7	0.7	0.6	0.6	0.6	0.3	0.6	0.1	0.8	0.8	-1.1	0.6	0.6	0.7	0.6
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.7	-0.6	-0.8	-0.8	-0.8	-0.4	-0.7	-0.7	-1.2	-0.4	-1.3	-1.0	-0.4	0.6	-0.2	-1.1	-0.7	-0.7
Multivitamins +/- minerals	0.3	0.4	0.6	-0.6	-0.7	-0.7	-0.7	-0.7	-0.5	-0.7	0.5	0.4	-0.3	-0.6	-0.7	-0.1	-0.8	-0.4	-0.7	-0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	4.2	-0.4	-0.2	-0.2	-0.2	-0.1	-0.1	-0.2	-0.3	-0.7	-2.0	-0.3	-0.1	0.8	-0.6	-0.5	-0.3	-0.1
Medication: Ramipril	0.3	0.4	1.4	-0.4	-0.4	-0.5	-0.4	-0.3	-0.7	-0.4	-0.7	1.2	-0.8	-0.5	-0.4	0.7	-0.6	-0.8	-0.5	-0.1
Worrier / anxious feelings	0.3	0.7	3.4	0.5	0.5	0.6	0.5	0.4	0.6	0.4	1.3	1.8	-0.5	0.8	0.6	-1.3	0.4	1.0	0.5	0.3
Impedance of arm (left)	0.3	1.3	2.0	-1.2	-1.1	-1.1	-1.1	-1.4	-0.9	-1.3	-0.8	0.6	0.8	-1.1	-1.2	-1.2	-1.2	-1.3	-1.3	-1.2
Breastfed as a baby	0.3	0.4	0.9	0.7	0.8	0.7	0.8	1.0	0.3	0.9	-0.2	0.1	0.7	0.7	0.5	-0.4	0.8	0.3	0.7	0.8
Glaucoma (self-reported)	0.3	0.3	1.7	0.2	0.2	0.4	0.2	-0.2	0.4	0.0	0.9	-0.6	0.9	0.4	0.4	-1.3	0.4	0.7	0.3	0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	4.1	0.7	0.6	0.8	0.6	0.5	0.3	0.4	2.0	0.5	0.8	0.9	0.9	0.4	0.6	1.0	0.9	0.4
Number of full brothers	0.3	0.3	0.9	0.7	0.6	0.6	0.6	0.5	0.4	0.5	0.5	-0.5	1.0	0.6	0.7	0.0	0.7	0.5	0.6	0.6
Shortness of breath walking on level ground	0.3	0.4	2.3	-0.2	-0.1	-0.2	-0.1	0.0	0.1	0.3	-1.2	-1.5	1.5	-0.3	-0.4	0.1	-0.1	-0.4	-0.2	0.1
Medication: Blood pressure	0.3	0.5	3.2	-0.3	-0.2	-0.3	-0.2	-0.2	-0.1	-0.1	-0.5	-1.0	-1.8	-0.3	-0.5	1.7	-0.2	-0.1	-0.3	-0.1
Leg pain on walking	0.3	0.4	2.9	0.1	0.2	0.1	0.2	0.2	0.5	0.3	-0.5	-1.1	1.7	0.1	0.0	1.1	0.1	-0.1	-0.0	0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	6.8	0.1	0.0	-0.0	0.0	0.2	0.2	0.2	-0.1	2.6	-0.0	0.0	-0.1	-0.3	0.1	-0.1	0.1	0.1
Medication: Aspirin	0.3	0.4	1.2	0.4	0.4	0.3	0.4	0.5	-0.3	0.6	0.3	1.1	-1.1	0.4	0.5	1.0	0.5	0.2	0.5	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.5	-0.4	-0.4	-0.4	-0.4	-0.2	-0.9	-0.3	-1.2	-0.6	0.8	-0.5	-0.2	-0.7	-0.4	-1.1	-0.4	-0.3
Mood swings	0.3	0.5	4.9	-0.4	-0.4	-0.3	-0.4	-0.9	-0.4	-0.7	0.9	0.5	0.7	-0.2	0.1	-2.2	-0.5	0.1	-0.5	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	2.0	0.3	0.3	0.3	0.3	0.4	0.0	0.5	0.3	1.1	1.4	0.3	0.3	0.4	0.1	-0.1	0.3	0.3
Friendships satisfaction	0.3	0.4	1.9	-0.5	-0.6	-0.6	-0.6	-0.4	-0.9	-0.4	-0.4	1.4	0.6	-0.5	-0.6	-0.4	-0.5	-0.7	-0.4	-0.4
Mineral and other dietary supplements	0.3	0.5	1.9	0.7	0.7	0.7	0.7	0.7	0.7	0.6	0.3	1.4	-0.2	0.7	0.5	-0.3	0.6	0.5	0.7	0.8
Osteoporosis (self-reported)	0.3	0.3	2.0	-0.3	-0.4	-0.4	-0.4	-0.4	-0.5	-0.6	0.4	-1.0	0.4	-0.3	-0.3	-1.4	-0.6	-0.2	-0.3	-0.7
Number of self-reported non-cancer illnesses	0.3	0.4	3.5	0.5	0.3	0.5	0.3	0.3	0.3	0.1	1.9	-0.7	-1.0	0.6	0.6	-0.1	0.4	0.8	0.5	0.1
Medication: Blood pressure	0.3	0.6	7.5	0.1	0.1	-0.0	0.1	0.1	0.1	0.3	-1.3	-0.3	-0.6	-0.2	-0.2	2.7	-0.1	-0.3	-0.0	0.5
Leg fat percentage (left)	0.3	1.1	5.1	-0.9	-0.9	-0.9	-0.9	-0.7	-1.1	-0.9	-0.9	-2.2	-1.2	-1.0	-1.0	-0.0	-0.7	-1.2	-0.9	-0.7
Number of operations (self-reported)	0.3	0.4	4.0	-0.2	-0.4	-0.4	-0.4	0.1	-0.7	-0.2	0.5	-0.7	0.1	-0.4	-0.3	2.0	-0.2	-0.7	-0.2	-0.3
Risk taking	0.3	0.5	1.4	-0.6	-0.6	-0.7	-0.6	-0.6	-0.4	-0.6	-1.0	-1.2	0.5	-0.8	-0.5	0.4	-0.6	-0.6	-0.7	-0.5
Diastolic blood pressure, automated reading	0.3	0.8	1.3	1.1	1.0	1.0	1.0	1.1	0.2	0.9	0.5	-1.1	0.1	1.0	0.7	0.9	1.1	0.5	1.1	1.2
Pain experienced in last month	0.3	0.5	1.1	-0.7	-0.7	-0.7	-0.7	-0.6	-0.6	-0.5	-0.4	1.1	0.1	-0.7	-0.9	0.9	-0.7	-0.6	-0.6	-0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.5	2.0	-0.6	-0.5	-0.6	-0.5	-0.5	-0.6	-0.4	-1.4	-0.7	-0.6	-0.7	-0.8	0.2	-0.5	-0.8	-0.7	-0.4
Heart disease (siblings)	0.3	0.4	6.2	-0.2	-0.2	-0.2	-0.2	-0.2	0.0	-0.3	-0.3	0.1	-2.5	-0.2	-0.5	-0.4	-0.3	-0.2	-0.2	-0.0
Impedance of whole body	0.3	1.6	3.2	-1.3	-1.2	-1.2	-1.2	-1.8	-0.7	-1.6	-0.7	-0.3	1.1	-1.2	-1.2	-1.7	-1.3	-1.2	-1.5	-1.3
Schizophrenia vs Biploar Disorder	0.2	0.2	1.5	0.2	0.2	0.1	0.2	0.2	0.3	0.3	-0.0	-1.2	1.1	0.2	0.1	-0.5	0.1	0.3	0.2	0.3
Crohns Disease (2017)	0.2	0.5	2.2	-0.6	-0.7	-0.7	-0.7	-0.7	-0.9	-0.7	-0.4	0.3	-1.5	-0.6	-0.8	-0.4	-0.6	-0.5	-0.6	-0.5
Ulcerative Colitis (UC)	0.2	0.3	0.8	0.5	0.5	0.5	0.5	0.5	0.6	0.5	0.2	0.7	0.9	0.5	0.5	0.5	0.6	0.6	0.5	0.5
Breast Cancer	0.2	0.4	3.5	0.3	0.3	0.4	0.3	0.2	0.1	-0.0	1.3	1.9	-0.6	0.4	0.3	0.0	0.5	0.6	0.4	-0.1
Fasting Glucose	0.2	0.2	0.9	-0.3	-0.1	-0.1	-0.1	-0.1	-0.4	0.2	-1.0	0.8	-0.5	-0.3	-0.2	0.4	-0.1	-0.7	-0.5	-0.1
BMI	0.2	1.1	12.2	0.7	0.6	0.6	0.6	1.0	0.5	0.7	0.3	-0.3	-3.5	0.6	0.9	0.8	0.5	0.5	0.7	0.8
Waist Hip Ratio (WHR)	0.2	0.8	2.5	-0.7	-0.7	-0.6	-0.7	-0.9	-0.2	-0.9	1.6	-1.5	-1.4	-0.4	-0.6	-0.7	-0.8	-0.1	-0.8	-0.7
Cardiovascular Disease	0.2	0.7	4.2	0.2	0.2	0.2	0.2	0.2	0.3	0.3	-0.5	-1.5	-2.1	0.2	0.1	2.0	0.0	0.1	0.1	0.8
Lung FEV1/FVC ratio	0.2	1.1	5.9	-0.7	-0.8	-0.7	-0.8	-1.1	-0.5	-1.2	0.9	-1.7	-2.4	-0.5	-0.6	-0.5	-0.8	0.2	-0.6	-1.0
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.8	0.4	0.4	0.3	0.4	0.7	0.0	0.7	-0.9	0.5	-0.4	0.2	0.2	0.9	0.4	-0.2	0.4	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	2.7	0.1	0.1	0.1	0.1	-0.1	-0.1	0.0	-0.1	0.4	1.6	0.0	-0.1	-0.1	0.3	0.1	0.1	0.1
Supplements: Zinc	0.2	0.2	1.4	0.2	0.1	0.0	0.1	0.2	0.4	0.3	-1.2	0.4	-0.6	-0.1	0.2	1.0	0.1	0.0	0.1	0.4
Taking other prescription medications	0.2	0.3	1.2	0.4	0.3	0.3	0.3	0.7	0.3	0.5	0.2	1.1	-0.7	0.3	0.3	0.9	0.4	0.0	0.4	0.3
Age when periods started (menarche)	0.2	0.5	2.1	0.5	0.6	0.7	0.6	0.4	0.6	0.3	1.5	-0.3	-0.4	0.8	1.0	-0.3	0.5	1.2	0.6	0.4
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.3	-0.2	-0.1	-0.1	-0.1	-0.5	0.3	-0.4	0.7	0.8	0.6	0.1	0.1	1.2	-0.0	0.2	-0.3	-0.2
Qualifications: CSEs or equivalent	0.2	0.3	1.7	-0.2	-0.2	-0.1	-0.2	-0.3	-0.8	-0.4	0.9	-0.5	1.3	0.0	0.1	-1.1	-0.2	-0.2	-0.2	-0.1
Stomach or abdominal pain in last month	0.2	0.3	1.8	0.1	0.0	0.1	0.0	0.2	-0.5	-0.1	0.8	1.2	-1.4	0.2	0.3	-0.4	-0.0	0.3	0.2	-0.1
Medication: Levothyroxine sodium	0.2	0.3	2.2	0.2	0.1	0.2	0.1	-0.2	0.1	-0.2	1.5	0.5	1.3	0.4	0.3	0.4	0.2	0.7	0.2	-0.1
High blood pressure (mother)	0.2	0.2	0.6	-0.4	-0.5	-0.5	-0.5	-0.4	-0.8	-0.6	0.3	-0.3	-0.4	-0.5	-0.4	0.8	-0.4	-0.2	-0.3	-0.4
Nervous feelings	0.2	0.4	0.8	0.8	0.7	0.7	0.7	0.9	0.7	0.9	-0.2	-0.3	-0.6	0.7	0.7	-0.7	0.6	0.4	0.7	0.8
Forced vital capacity (FVC)	0.2	0.6	3.4	-0.3	-0.2	-0.2	-0.2	0.0	-0.7	0.2	-1.6	-1.4	1.8	-0.4	-0.1	0.2	-0.1	-1.0	-0.2	-0.1
Medication: Simvastatin	0.2	0.4	0.9	0.5	0.5	0.5	0.5	0.3	0.7	0.5	0.2	-0.8	-0.6	0.5	0.3	1.0	0.6	0.9	0.5	0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.0	-0.7	-0.6	-0.6	-0.6	-0.6	-1.0	-0.5	-1.0	-1.0	0.4	-0.7	-0.4	-0.8	-0.6	-0.9	-0.6	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	2.0	-0.4	-0.4	-0.3	-0.4	-0.7	0.1	-0.6	0.9	-0.1	-0.2	-0.1	-0.1	-1.4	-0.3	0.1	-0.4	-0.5
Medication: Lansoprazole	0.2	0.2	1.2	0.1	0.2	0.2	0.2	0.2	-0.2	0.2	0.9	0.8	-1.1	0.2	0.3	-0.5	0.0	-0.0	0.2	-0.1
Heart disease (mother)	0.2	0.2	0.8	-0.4	-0.3	-0.4	-0.3	-0.2	-0.4	-0.2	-0.6	-0.9	0.1	-0.4	-0.9	0.4	-0.4	-0.5	-0.4	-0.2
Leg fat mass (right)	0.2	0.6	2.8	0.6	0.5	0.4	0.5	1.0	0.3	0.8	-0.6	-1.7	-0.5	0.3	0.3	1.6	0.8	0.1	0.6	0.8
Family relationship satisfaction	0.2	0.2	1.3	0.4	0.3	0.3	0.3	0.3	0.2	0.3	-1.1	-1.1	0.4	0.2	0.2	-0.8	0.1	0.2	0.3	0.3
Average weekly red wine intake	0.2	0.3	1.5	0.1	0.1	0.2	0.1	-0.4	0.1	-0.2	0.9	1.2	-1.2	0.2	0.4	-0.8	0.3	0.8	0.1	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.4	0.2	0.3	0.3	0.3	0.2	0.5	0.2	0.2	1.2	0.8	0.3	0.4	0.7	0.2	0.1	0.1	0.3
Long-standing illness, disability or infirmity	0.2	0.3	2.2	-0.4	-0.5	-0.6	-0.5	-0.3	-0.3	-0.4	-1.5	0.2	-0.0	-0.7	-0.6	0.7	-0.3	-0.7	-0.5	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.1	0.6	0.5	0.5	0.5	0.6	0.5	0.5	1.1	-0.4	-0.8	0.5	0.3	0.4	0.5	0.7	0.6	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.7	0.5	0.5	0.4	0.5	0.8	0.7	0.7	0.3	0.2	0.4	0.4	0.3	0.8	0.7	0.3	0.5	0.4
Medication: Aspirin	0.2	0.3	1.8	0.2	0.2	0.2	0.2	0.4	-0.4	0.5	0.1	0.9	-1.4	0.2	0.3	0.9	0.4	-0.0	0.3	0.6
Medication: Gliclazide	0.2	0.3	2.5	-0.2	-0.2	-0.2	-0.2	-0.5	-0.2	-0.3	0.6	0.9	0.0	-0.1	-0.2	-1.6	-0.2	0.0	-0.2	-0.3
Medication: Paracetamol	0.2	0.3	1.9	-0.4	-0.5	-0.5	-0.5	-0.2	-0.8	-0.6	-0.4	-0.3	-1.4	-0.6	-0.2	-0.1	-0.3	-0.8	-0.4	-0.5
Illnesses of father: High blood pressure	0.2	0.2	1.9	0.0	-0.1	-0.2	-0.1	0.1	0.4	0.1	-0.5	-0.7	-1.0	-0.2	0.0	1.4	0.0	-0.2	0.0	0.2
Irritability	0.2	0.4	3.1	0.2	0.2	0.1	0.2	0.0	0.3	0.2	-0.4	1.8	1.0	0.2	0.4	-1.1	0.1	0.3	0.1	0.2
Ever depressed for a whole week	0.2	0.2	1.2	0.1	0.3	0.2	0.3	0.5	0.3	0.5	-0.6	-0.5	0.6	0.2	-0.0	1.1	-0.0	-0.2	0.1	0.5
Leg fat mass (left)	0.2	0.8	3.0	0.8	0.7	0.6	0.7	1.1	0.5	1.0	-0.5	-1.7	-0.9	0.5	0.5	1.5	0.9	0.3	0.7	1.0
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	-0.1	-0.2	-0.1	-0.2	-0.4	0.2	-0.3	0.6	-0.2	-0.5	-0.1	-0.4	-0.1	-0.0	0.4	-0.2	-0.5
Primary Biliary Cirrhosis	0.1	0.1	1.4	-0.2	-0.2	-0.2	-0.2	-0.4	-0.4	-0.4	0.4	-0.1	-0.2	-0.1	-0.0	-1.2	0.0	-0.2	-0.2	-0.3
Blood White Count	0.1	0.8	4.4	0.8	0.7	0.6	0.7	1.2	0.9	1.2	-0.4	0.5	2.1	0.5	0.6	1.1	0.7	0.2	0.7	1.0
Systolic Blood Pressure	0.1	0.7	1.8	0.9	0.9	0.9	0.9	0.9	0.4	0.9	0.3	-0.4	-1.4	0.9	0.9	0.7	0.7	0.5	0.8	1.3
Allergy or Eczema	0.1	0.2	1.1	-0.2	-0.3	-0.3	-0.3	-0.1	-0.0	-0.3	-1.1	-0.7	-0.6	-0.5	0.1	-0.1	0.3	-0.5	-0.3	-0.4
Tanning	0.1	1.2	3.0	-1.1	-1.2	-1.0	-1.2	-1.7	-0.8	-1.6	1.1	1.1	0.3	-0.9	-1.0	-1.1	-1.1	-0.0	-1.2	-1.4
Ever used hormone-replacement therapy (HRT)	0.1	0.2	2.1	-0.3	-0.2	-0.2	-0.2	-0.5	0.3	-0.5	0.3	0.1	-1.4	-0.1	-0.0	-0.1	-0.3	0.1	-0.3	-0.4
Ever had hysterectomy (womb removed)	0.1	0.1	0.6	0.2	0.1	0.1	0.1	0.1	-0.1	0.0	-0.1	0.8	0.6	0.1	0.6	0.6	0.5	-0.0	0.2	0.1
Medication for hormone replacement therapy	0.1	0.1	0.3	-0.4	-0.4	-0.4	-0.4	-0.5	-0.2	-0.5	0.0	-0.0	0.2	-0.3	-0.3	-0.4	-0.3	-0.2	-0.4	-0.5
Severe depression (siblings)	0.1	0.1	0.9	0.3	0.2	0.2	0.2	0.4	0.1	0.3	-0.2	-0.2	1.0	0.3	-0.1	-0.2	0.2	0.1	0.3	0.2
Trunk fat percentage	0.1	0.3	1.6	0.4	0.3	0.3	0.3	0.6	0.1	0.5	-0.8	-1.3	-1.1	0.1	0.1	0.8	0.5	-0.1	0.3	0.6
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.2	0.3	0.2	0.3	0.3	0.5	0.4	-0.5	-0.4	0.2	0.2	0.3	-0.0	0.2	0.1	0.2	0.3
Body mass index (BMI)	0.1	0.4	3.5	-0.4	-0.5	-0.5	-0.5	-0.1	-0.9	-0.4	-0.2	-0.6	-1.9	-0.6	-0.6	0.4	-0.3	-0.7	-0.4	-0.4
Number of incorrect matches in round	0.1	0.1	0.7	-0.2	-0.2	-0.2	-0.2	-0.3	0.3	-0.3	-0.5	0.2	-0.9	-0.2	-0.5	-0.6	-0.4	0.1	-0.3	-0.1
Had menopause	0.1	0.2	2.0	0.2	0.1	0.1	0.1	0.2	0.1	0.1	-0.4	-1.4	0.2	0.1	-0.2	-0.1	0.3	-0.1	0.2	0.2
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.5	-0.0	0.1	0.0	0.1	0.1	0.5	0.2	-0.3	0.3	0.1	-0.0	-0.2	0.7	-0.1	-0.0	-0.1	0.2
Mouth/teeth dental problems	0.1	0.2	1.7	-0.2	-0.3	-0.2	-0.3	-0.3	-0.4	-0.2	-0.1	1.3	0.7	-0.2	-0.0	0.5	-0.0	-0.1	-0.2	-0.4
Allergy	0.1	0.3	1.4	0.4	0.5	0.6	0.5	0.2	0.4	0.3	1.2	0.0	0.8	0.7	0.2	-0.2	0.0	0.9	0.5	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	1.0	-0.2	-0.3	-0.3	-0.3	0.1	-0.7	-0.2	0.2	1.0	-0.3	-0.3	-0.1	-0.4	-0.0	-0.6	-0.1	-0.3
Number of live births	0.1	0.1	0.9	-0.0	0.0	-0.0	0.0	-0.0	0.1	0.1	-0.1	-0.2	0.9	-0.1	0.3	0.5	0.1	-0.2	-0.0	0.0
Lung cancer (father)	0.1	0.1	1.2	0.1	0.1	0.1	0.1	0.3	-0.5	0.1	0.0	-1.1	0.1	0.1	0.0	0.0	0.1	-0.4	0.2	-0.0
Illnesses of mother	0.1	0.2	0.5	0.4	0.5	0.5	0.5	0.2	0.7	0.4	0.0	-0.1	0.3	0.5	0.7	0.1	0.4	0.4	0.3	0.6
Arm fat mass (right)	0.1	0.5	1.8	0.1	0.0	-0.1	0.0	0.6	-0.3	0.4	-1.2	-1.3	-1.2	-0.3	-0.2	1.4	0.2	-0.5	0.1	0.4
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	2.6	0.2	0.1	0.1	0.1	0.2	-0.1	0.1	-0.0	0.1	1.6	0.1	0.3	-1.1	0.2	-0.1	0.2	0.2
Birth weight	0.1	0.2	1.3	0.1	0.2	0.2	0.2	0.0	-0.1	0.2	0.5	-1.1	0.8	0.2	0.1	-0.0	0.3	0.4	0.2	0.2
Forced vital capacity (FVC), Best measure	0.1	0.5	3.0	0.3	0.4	0.4	0.4	0.5	0.1	0.8	-1.3	-0.9	1.7	0.2	0.5	0.4	0.4	-0.1	0.4	0.5
Body fat percentage	0.1	0.5	2.2	-0.4	-0.4	-0.5	-0.4	-0.1	-0.6	-0.3	-1.1	-1.5	-1.3	-0.6	-0.6	0.5	-0.2	-0.9	-0.5	-0.2
Medication for cholesterol	0.1	0.1	1.2	0.2	0.2	0.1	0.2	0.5	0.0	0.4	-0.3	0.1	1.1	0.1	0.2	-0.3	0.3	-0.2	0.2	0.2
Osteoarthritis (self-reported)	0.1	0.1	1.4	-0.2	-0.2	-0.1	-0.2	-0.4	0.3	-0.4	0.2	-0.5	-0.2	-0.1	0.1	-1.2	-0.0	0.3	-0.2	-0.3
Illnesses of father: None of the above (group 1)	0.1	0.2	0.8	0.1	0.2	0.3	0.2	-0.0	0.2	0.1	0.9	-0.2	-0.3	0.3	0.7	-0.8	0.2	0.4	0.1	0.3
Arm fat mass (left)	0.1	0.6	2.0	0.6	0.6	0.5	0.6	1.1	0.2	1.0	-0.8	-1.0	-1.1	0.3	0.4	1.4	0.8	0.1	0.6	0.9
Guilty feelings	0.1	0.2	0.8	0.3	0.4	0.5	0.4	-0.0	0.4	0.2	0.9	-0.6	-0.0	0.6	0.5	-0.5	0.4	0.5	0.3	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.1	1.5	0.1	0.1	0.1	0.1	-0.1	0.1	0.0	0.3	-1.2	0.2	0.2	0.3	-0.3	0.1	0.5	0.1	0.1
High cholesterol (Self-reported)	0.1	0.2	1.1	-0.0	-0.1	0.0	-0.1	-0.2	-0.3	-0.2	0.9	-1.1	-1.0	0.1	0.0	-0.1	0.1	0.4	0.1	-0.2
Irritable Bowel Disease (IBD)	0.0	0.1	0.4	-0.2	-0.3	-0.2	-0.3	-0.3	-0.3	-0.3	-0.1	0.6	-0.5	-0.2	-0.2	0.3	-0.2	0.0	-0.1	-0.2
Triglycerides	0.0	0.1	0.5	0.1	0.1	0.2	0.1	0.1	-0.4	-0.1	0.5	0.0	-0.2	0.1	-0.1	0.7	0.2	-0.1	0.1	0.0
Fluid intelligence score	0.0	0.1	0.9	0.0	0.1	0.1	0.1	0.0	-0.2	0.0	0.9	0.5	0.2	0.2	0.1	0.2	0.2	0.0	0.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.7	-0.1	-0.1	-0.1	-0.1	-0.2	-0.2	0.1	-0.7	-0.8	0.5	-0.2	0.2	-0.1	-0.1	-0.2	-0.0	-0.1
Tense / ‘highly strung’	0.0	0.1	0.7	0.1	0.1	0.0	0.1	0.2	-0.2	0.2	-0.4	0.0	0.8	0.1	-0.1	0.5	-0.1	0.0	0.1	0.3
Medication for pain relief, constipation, heartburn	0.0	0.1	0.8	0.2	0.2	0.3	0.2	0.1	0.3	0.1	0.3	0.2	0.9	0.2	0.1	0.0	0.0	0.3	0.2	0.1

Hub : Genes

C2orf82

Models

Trait associations