[Hub]/) : Traits : Schizophrenia (2014) :

chr2:197,134,790-202,078,494

Best TWAS P=2.05e-13 · Best GWAS P=1.11e-11 conditioned to 0.853

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C2orf47 0.05 0.02 blup 361 0.02 4.3e-03 6.8 -7.3 2.1e-13 -0.85 0.01 0.99 TRUE
2 CommonMind Brain Pre-frontal Cortex SF3B1 0.06 0.07 enet 10 0.07 2.5e-09 6.6 6.6 4.2e-11 0.05 0.02 0.98 FALSE
3 GTEx Brain Caudate basal ganglia TYW5 0.23 0.11 lasso 3 0.11 5.4e-04 4.4 -5.5 3.7e-08 -0.52 0.06 0.37 FALSE
4 GTEx Breast Mammary Tissue SF3B1 0.06 0.06 lasso 4 0.03 6.6e-03 6.6 6.7 1.5e-11 0.06 0.04 0.92 TRUE
5 GTEx Breast Mammary Tissue (Female) SF3B1 0.05 -0.01 lasso 3 -0.01 8.1e-01 6.7 6.7 1.7e-11 0.07 0.03 0.43 FALSE
6 GTEx Cells EBV-transformed lymphocytes MARS2 0.15 0.14 lasso 4 0.07 2.6e-03 -5.1 -5.1 2.8e-07 -0.09 0.13 0.30 FALSE
7 GTEx Cells Transformed fibroblasts C2orf69 0.07 0.10 enet 17 0.10 2.7e-08 6.7 5.7 1.5e-08 0.92 0.01 0.99 FALSE
8 GTEx Esophagus Mucosa SF3B1 0.04 0.02 lasso 4 0.01 5.7e-02 6.4 6.5 8.0e-11 0.06 0.05 0.85 FALSE
9 GTEx Esophagus Muscularis SF3B1 0.06 0.02 lasso 4 0.03 1.0e-02 5.6 5.3 1.1e-07 0.03 0.07 0.67 FALSE
10 GTEx Lung SF3B1 0.06 0.04 enet 23 0.02 2.2e-02 6.4 5.8 9.1e-09 0.07 0.03 0.94 FALSE
11 GTEx Nerve Tibial SF3B1 0.06 0.09 lasso 8 0.08 3.3e-06 6.7 6.2 4.2e-10 0.06 0.08 0.92 FALSE
12 GTEx Pituitary HSPD1 0.10 0.03 enet 12 0.06 1.3e-02 4.8 6.7 2.1e-11 0.09 0.08 0.39 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic SF3B1 0.08 0.00 enet 19 0.01 1.6e-01 6.5 5.7 1.2e-08 0.07 0.04 0.89 FALSE
14 GTEx Spleen KCTD18 0.26 0.03 lasso 4 0.04 3.8e-02 4.8 5.7 1.0e-08 0.85 0.11 0.35 FALSE
15 GTEx Spleen RFTN2 0.11 0.03 enet 26 0.05 2.4e-02 4.8 5.2 1.5e-07 0.08 0.11 0.23 FALSE
16 GTEx Spleen MARS2 0.12 0.04 lasso 5 0.00 3.4e-01 4.7 -5.2 1.8e-07 -0.07 0.08 0.23 FALSE
17 GTEx Stomach SF3B1 0.11 0.00 enet 19 0.00 4.0e-01 5.6 5.1 3.0e-07 0.06 0.06 0.44 FALSE
18 GTEx Testis ANKRD44 0.33 0.35 enet 15 0.36 6.2e-17 5.7 5.4 7.9e-08 0.07 0.74 0.26 FALSE
19 GTEx Testis SF3B1 0.10 0.07 enet 17 0.08 2.6e-04 6.6 6.3 3.5e-10 0.07 0.03 0.96 FALSE
20 GTEx Testis C2orf69 0.14 0.09 enet 17 0.10 2.7e-05 6.8 6.8 9.7e-12 0.93 0.02 0.98 FALSE
21 GTEx Thyroid SF3B1 0.04 0.02 enet 14 0.02 2.0e-02 5.3 5.7 1.2e-08 0.08 0.09 0.83 FALSE
22 GTEx Thyroid PLCL1 0.04 0.01 lasso 4 0.00 2.6e-01 4.4 5.5 3.4e-08 0.08 0.16 0.60 FALSE
23 GTEx Whole Blood C2orf47 0.04 0.05 lasso 2 0.03 3.6e-04 6.6 6.6 4.4e-11 1.00 0.02 0.97 FALSE
24 METSIM Adipose C2orf69 0.04 0.03 blup 376 0.04 1.3e-06 4.2 5.7 1.0e-08 0.84 0.04 0.96 FALSE
25 NTR Blood ANKRD44 0.03 0.00 bslmm 417 0.02 2.7e-06 6.0 -6.5 7.7e-11 -0.07 0.07 0.88 FALSE
26 ROSMAP Brain Pre-frontal Cortex SF3B1 0.02 0.01 blup 336 0.01 6.2e-03 5.4 6.0 2.0e-09 0.07 0.06 0.91 FALSE
27 YFS Blood ANKRD44 0.02 0.00 blup 416 0.01 6.3e-04 2.4 -6.6 3.4e-11 -0.04 0.10 0.63 FALSE
28 The Cancer Genome Atlas Colon Adenocarcinoma C2orf60 0.08 0.06 enet 11 0.06 1.4e-04 6.6 -6.3 3.6e-10 -0.91 0.01 0.94 FALSE
29 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C2orf69 0.02 0.00 blup 35 0.01 2.6e-02 3.3 5.7 1.6e-08 0.85 0.02 0.76 FALSE
30 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RFTN2 0.05 0.01 blup 61 0.02 3.1e-02 6.5 6.2 6.0e-10 0.07 0.02 0.71 FALSE
31 The Cancer Genome Atlas Testicular Germ Cell Tumors C2orf47 0.15 0.05 blup 39 0.05 7.6e-03 6.7 -5.8 6.8e-09 -0.94 0.00 0.97 FALSE
32 The Cancer Genome Atlas Testicular Germ Cell Tumors C2orf60 0.15 0.05 enet 12 0.08 8.2e-04 6.6 -5.6 2.0e-08 -0.86 0.01 0.98 FALSE