Best TWAS P=1.03e-09 · Best GWAS P=2.01e-11 conditioned to 0.429
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | HSD17B1P1 | 0.09 | 0.14 | lasso | 1 | 0.07 | 1.2e-02 | 5.7 | -5.7 | 1.6e-08 | -0.68 | 0.03 | 0.10 | TRUE |
| 2 | GTEx | Muscle Skeletal | HSD17B1P1 | 0.05 | 0.03 | lasso | 3 | 0.02 | 2.0e-03 | 5.7 | -5.3 | 1.4e-07 | -0.66 | 0.20 | 0.29 | FALSE |
| 3 | GTEx | Spleen | CNTNAP1 | 0.20 | 0.16 | enet | 12 | 0.16 | 7.2e-05 | 2.7 | 5.1 | 3.1e-07 | 0.70 | 0.10 | 0.44 | FALSE |
| 4 | GTEx | Spleen | CTD-3193K9.3 | 0.16 | 0.10 | enet | 24 | 0.14 | 1.6e-04 | 2.7 | 5.9 | 4.2e-09 | 0.62 | 0.18 | 0.16 | FALSE |
| 5 | METSIM | Adipose | PTRF | 0.03 | 0.02 | lasso | 3 | 0.01 | 3.3e-03 | -6.1 | 6.1 | 1.0e-09 | 0.39 | 0.04 | 0.96 | TRUE |
| 6 | NTR | Blood | FAM134C | 0.01 | 0.00 | bslmm | 265 | 0.00 | 8.2e-03 | -6.1 | 5.2 | 2.1e-07 | 0.32 | 0.04 | 0.25 | FALSE |
| 7 | YFS | Blood | FAM134C | 0.03 | 0.01 | enet | 12 | 0.01 | 1.2e-05 | -1.7 | 5.4 | 5.2e-08 | 0.56 | 0.17 | 0.53 | FALSE |