Hub : Genes

ZNF839

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0850 0.0330 1.8e-03 -0.001 0.015 0.012 0.015 0.002 3.9e-01 5.5e-03 1.0e-02 0.005 1.7e-01
2 GTEx Adipose Subcutaneous 0.1030 0.0360 2.2e-04 0.005 NA 0.031 NA 0.013 1.2e-01 NA 1.3e-03 NA 2.6e-02
3 GTEx Adrenal Gland 0.2149 0.0788 2.8e-03 -0.007 NA 0.032 NA 0.011 7.0e-01 NA 2.6e-02 NA 1.3e-01
4 GTEx Artery Tibial 0.1443 0.0518 4.7e-04 0.076 NA 0.058 NA 0.064 1.5e-06 NA 2.5e-05 NA 9.2e-06
5 GTEx Brain Cerebellum 0.2170 0.0870 1.7e-03 0.039 NA 0.028 NA 0.066 2.7e-02 NA 5.1e-02 NA 5.2e-03
6 GTEx Muscle Skeletal 0.1147 0.0381 6.1e-05 0.095 NA 0.059 NA 0.073 1.3e-09 NA 2.0e-06 NA 1.1e-07
7 GTEx Nerve Tibial 0.0802 0.0368 9.5e-03 -0.002 NA 0.008 NA 0.007 4.8e-01 NA 7.9e-02 NA 9.2e-02
8 GTEx Ovary 0.2810 0.0860 9.3e-04 0.054 NA 0.186 NA 0.182 1.9e-02 NA 2.5e-05 NA 3.0e-05
9 GTEx Pituitary 0.3780 0.1210 1.0e-03 0.195 NA 0.161 NA 0.175 1.2e-05 NA 7.5e-05 NA 3.6e-05
10 GTEx Testis 0.3660 0.0860 1.5e-06 0.206 NA 0.168 NA 0.192 1.7e-09 NA 6.6e-08 NA 6.1e-09
11 GTEx Thyroid 0.1010 0.0360 5.7e-06 0.076 NA 0.128 NA 0.115 1.8e-06 NA 5.6e-10 NA 4.1e-09
12 TCGA Bladder Urothelial Carcinoma 0.0420 0.0220 1.4e-03 0.002 0.016 0.025 NA 0.006 2.0e-01 1.5e-02 3.2e-03 NA 9.1e-02
13 TCGA Head and Neck Squamous Cell Carcinoma 0.0549 0.0269 3.5e-04 0.006 0.009 0.011 NA 0.013 6.5e-02 2.8e-02 1.9e-02 NA 1.2e-02
14 TCGA Kidney Renal Clear Cell Carcinoma 0.0448 0.0235 1.5e-03 0.001 0.010 0.000 NA -0.001 2.2e-01 2.4e-02 3.3e-01 NA 4.1e-01
15 TCGA Liver Hepatocellular Carcinoma 0.1900 0.0810 5.8e-04 -0.006 0.082 0.073 NA 0.001 8.6e-01 1.1e-04 2.4e-04 NA 3.0e-01
16 TCGA Lung Squamous Cell Carcinoma 0.0532 0.0243 6.8e-05 0.031 0.041 0.046 NA 0.049 1.6e-04 1.6e-05 5.5e-06 NA 2.6e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bipolar Disorder (2018) 1.1 1.7 4.2 1.3 -0.6 0.4 0.9 -1.9 0.7 -1.6 -1.6 -1.2 1.0 -1.8 1.4 1.5 2.0 0.8 0.0
Bipolar Disorder or Schizophrenia 1.1 2.6 5.3 1.0 0.8 0.1 1.8 -1.6 2.1 -1.2 -2.1 -1.1 2.1 -1.5 2.2 1.7 2.3 1.0 1.3
Depressed Affect (Nagel 2018) 2.0 4.2 13.6 -0.2 3.1 1.6 1.4 -0.3 2.5 1.0 1.5 0.2 1.7 -0.3 3.5 0.1 2.0 3.7 3.2
Depression (Nagel 2018) 0.6 0.9 3.6 -0.3 1.4 0.7 0.2 0.9 0.9 1.9 0.9 1.5 0.5 0.9 1.3 -0.5 -0.4 -0.1 1.2
Intelligence (Savage-Jansen 2018) 0.5 1.6 7.3 1.8 -2.7 -0.1 -0.5 -1.7 -1.7 -0.9 -0.9 -1.0 -0.7 -0.9 0.8 1.2 1.0 0.3 -1.4
Neuroticism (Nagel 2018) 1.2 2.9 9.6 0.5 2.6 1.1 1.1 -0.4 1.9 1.2 1.5 0.4 1.3 -0.5 3.1 0.8 1.5 2.7 2.6
Schizophrenia (2018) 0.7 1.5 4.5 0.5 1.5 -0.2 1.6 -0.5 2.1 -0.2 -1.2 -0.4 1.9 -0.5 1.7 1.1 1.3 0.7 1.6
Schizophrenia vs Biploar Disorder 0.2 0.3 2.3 -1.1 -0.2 -1.5 -0.2 0.3 -0.1 -0.2 0.0 0.1 -0.2 0.3 -0.2 -0.5 -0.6 -0.5 -0.0
Worry (Nagel 2018) 0.6 1.3 7.1 0.9 1.0 0.3 0.4 0.9 0.7 2.7 1.3 1.7 0.5 1.1 1.4 0.4 0.0 0.8 1.4
Alzheimer’s Disease (in mother) 1.8 2.1 5.8 -0.8 0.9 -1.0 1.9 -1.0 1.7 0.7 -0.4 -0.9 2.0 -1.1 2.4 1.2 1.2 1.8 2.0
Alzheimer’s Disease (in father) 0.8 0.9 2.8 -0.0 -0.2 -1.7 1.2 -1.0 1.1 0.1 -1.0 -0.5 1.2 -0.9 1.3 1.2 0.5 0.3 0.9
Alzheimer’s Disease (including proxy) 1.7 2.5 6.5 -0.4 0.0 -2.1 2.0 -1.6 1.8 0.5 -1.0 -1.2 2.1 -1.6 2.6 1.8 1.3 1.4 1.8
Crohns Disease (2017) 0.8 1.8 7.4 -1.8 -1.0 -1.4 -1.3 -1.7 -0.4 -1.0 -2.7 -1.4 -1.1 -1.6 0.2 1.3 0.5 0.3 -1.1
Irritable Bowel Disease (IBD) 1.2 2.8 10.1 -0.3 -1.5 -0.9 -1.5 -2.1 -1.0 -2.3 -3.2 -1.8 -1.4 -2.3 0.6 1.5 1.2 0.5 -1.7
Ulcerative Colitis (UC) 0.9 1.8 5.7 0.9 -1.2 -0.1 -0.8 -1.5 -1.0 -2.4 -2.4 -1.1 -0.8 -1.8 0.7 1.0 1.3 0.5 -1.4
Major Depression (MDD) 0.8 1.0 4.6 1.7 -0.1 2.1 0.6 -0.9 0.8 -0.7 0.3 -1.1 0.9 -0.2 0.8 -0.0 1.2 1.3 0.7
Reaction Time 0.6 1.2 8.7 -0.1 0.7 0.7 -0.3 -1.4 0.2 -1.0 -0.2 -0.6 -0.1 -2.0 -0.0 3.0 0.5 1.3 0.0
Verbal and Numeric Reasoning (VNR) 0.4 0.9 6.1 0.5 -2.5 -1.3 -0.8 -1.0 -0.7 -1.0 -0.8 -0.6 -0.8 -0.6 0.2 0.4 -0.0 -0.4 -0.7
Breast Cancer 0.3 0.8 2.0 0.8 1.4 0.6 1.1 0.3 1.3 -0.4 0.9 -0.2 1.2 -0.4 0.3 0.1 0.6 1.1 1.4
Ovarian Cancer 0.5 0.7 1.8 -0.6 1.3 -0.6 1.2 0.3 1.3 0.4 0.0 0.1 1.3 0.3 0.9 -0.5 -0.7 -0.8 1.3
Prostate Cancer 0.5 0.8 2.4 0.9 -0.5 1.6 -0.4 1.0 -0.4 1.2 1.5 0.4 -0.5 1.1 -0.7 -1.0 -0.6 -0.3 -0.2
Age at First Birth 0.8 1.2 3.0 -0.2 1.4 1.0 -0.5 1.7 -1.2 0.3 -0.1 1.5 -0.7 1.2 -1.6 -0.9 -0.5 -0.9 -1.5
Bipolar Disorder (2011) 1.7 1.7 4.3 -1.4 0.5 0.8 1.4 -1.4 1.3 -2.1 -1.9 -1.1 1.4 -1.3 1.3 0.4 1.7 0.2 0.6
Body Mass Index (BMI) (2010) 1.8 2.5 7.0 0.1 -0.5 0.7 -1.0 2.5 0.1 2.3 1.7 1.9 -0.8 2.6 -2.2 -1.3 -2.5 -0.8 0.2
Coronary Artery Disease (CAD) 1.1 1.4 4.6 -0.6 -1.3 -1.4 -0.1 -1.9 -0.3 -1.2 -2.2 -1.5 -0.3 -1.5 0.6 1.1 0.8 -0.5 -0.9
Crohns Disease (2012) 1.6 2.6 7.7 -2.5 0.4 -1.2 -0.3 -2.5 0.4 -1.2 -2.8 -2.0 -0.1 -2.6 1.1 2.1 0.8 0.4 -0.2
Mean Putamen Volume 3.2 3.7 7.6 1.1 -1.8 -0.8 -2.4 2.0 -1.7 1.7 1.2 1.1 -2.5 2.5 -2.8 -2.1 -2.7 -1.5 -1.5
Fasting Glucose 2.6 3.2 9.0 0.7 -1.5 -0.8 -1.4 3.0 -0.7 2.6 1.2 2.9 -1.4 3.0 -2.0 -0.9 -1.8 -0.3 -0.4
HbA1C 1.3 1.4 6.7 1.7 -0.8 0.3 -0.5 0.2 -0.2 -1.3 1.2 -0.7 -0.6 0.3 -1.5 -2.6 -1.1 -2.1 -0.4
HDL Cholesterol 0.6 1.1 2.6 -0.8 0.4 -1.0 0.6 -1.6 0.7 -1.0 -0.9 -1.3 0.7 -1.4 1.4 1.2 1.1 0.8 0.6
LDL Cholesterol 0.3 0.5 1.9 -0.4 -0.6 0.6 -0.1 1.1 -0.3 1.0 0.5 1.4 -0.2 1.0 -0.6 -0.4 -0.7 -0.1 -0.0
Lupus 0.6 0.9 4.9 -0.1 -1.0 -0.9 1.3 -0.6 0.9 -0.7 -2.2 -0.9 1.1 -0.2 0.2 0.4 0.6 -1.0 0.1
Neuroticism (2016) 0.7 1.1 2.8 1.0 0.8 0.6 1.2 -0.6 1.7 -0.7 0.5 -0.7 1.4 -0.9 1.5 0.0 0.6 1.2 1.6
Primary Biliary Cirrhosis 0.4 0.5 1.8 0.3 0.9 0.9 0.3 0.9 1.3 0.9 0.3 0.6 0.5 0.8 -0.4 -0.6 -0.2 0.4 1.0
Rheumatoid Arthritis 0.5 0.7 4.5 0.4 -0.3 0.3 -0.7 0.5 -0.5 -0.0 1.0 -0.6 -0.8 0.3 -1.1 -2.1 -0.9 -0.8 -0.4
Schizophrenia (2014) 1.0 2.2 7.6 -0.3 1.5 0.3 2.3 -0.3 2.8 -0.2 -1.1 -0.4 2.5 -0.3 1.8 0.7 1.5 0.6 2.1
Triglycerides 0.8 1.3 3.3 -0.9 -1.5 -1.0 -0.9 1.2 -0.5 0.1 1.3 1.2 -1.1 0.9 -1.5 -1.4 -1.8 -1.2 -0.5
Type 2 Diabetes (T2D) (2012) 2.0 2.3 6.4 0.6 -1.5 0.8 -1.3 2.0 -0.8 -0.1 1.0 1.3 -1.1 1.8 -2.3 -1.2 -2.5 -2.5 -0.7
Ulcerative Colitis 1.3 1.9 4.6 -0.3 -0.7 -0.0 -1.8 -1.3 -2.1 -2.1 -2.0 -1.1 -1.9 -1.5 0.2 0.8 0.4 -0.6 -2.1
Blood Eosinophil Count 0.7 5.5 11.7 0.6 -2.8 -2.4 -3.3 1.5 -2.5 -0.4 -1.5 1.4 -3.1 1.9 -3.4 -2.0 -3.0 -1.9 -2.9
Blood Platelet Count 4.0 45.9 158.8 -2.0 11.8 12.6 4.9 -6.5 3.5 -6.7 -7.8 -6.2 5.1 -6.3 5.2 4.0 9.6 2.8 0.5
Blood Red Count 0.3 2.9 8.6 2.0 0.9 1.9 2.9 -1.3 1.4 0.8 0.7 -0.4 2.7 -1.1 2.0 2.1 1.9 1.3 1.6
Blood White Count 0.2 1.8 10.8 3.3 1.8 1.9 0.5 0.9 1.2 0.0 1.7 0.3 0.8 0.7 -0.2 -0.5 -0.5 1.1 1.5
Heel T-Score 0.1 0.7 3.0 -1.3 -0.8 0.7 -0.8 1.1 0.3 -0.2 0.4 -0.6 -0.6 0.8 -0.9 -1.7 -1.0 -0.3 0.1
BMI 1.4 8.3 27.4 2.2 2.5 1.4 0.2 5.2 1.8 3.3 3.1 3.3 0.5 4.9 -2.9 -3.8 -2.7 -0.6 1.8
Height 0.9 16.9 55.7 2.2 0.7 2.2 2.5 -6.2 0.2 -4.9 -7.5 -3.8 2.0 -5.0 3.1 5.8 6.6 -0.5 -2.3
Waist Hip Ratio (WHR) 0.4 1.6 16.2 4.0 -0.8 1.7 1.0 -0.2 1.0 -0.3 -0.2 -0.9 1.1 0.0 -0.1 0.1 0.9 0.7 0.6
Systolic Blood Pressure 0.5 2.6 10.1 3.2 0.6 0.8 2.8 -0.9 1.8 -0.1 0.1 -1.2 2.6 -0.8 1.7 0.1 2.1 0.8 1.4
Smoking Status 0.6 1.4 3.5 -1.9 0.9 1.6 0.7 -1.6 1.0 -0.2 -1.4 -1.1 0.8 -1.0 0.6 1.7 1.3 0.9 0.4
Allergy or Eczema 1.2 3.3 12.7 0.7 -3.6 -2.9 -2.0 1.2 -1.7 0.8 0.3 1.1 -2.1 1.0 -2.2 0.1 -2.6 -1.2 -1.4
Cardiovascular Disease 0.4 1.2 6.1 2.5 -0.6 1.7 -0.6 1.0 0.2 1.0 1.5 0.3 -0.7 1.2 -1.2 -0.7 -0.6 0.4 0.3
Hypothyroidism (self reported) 0.4 1.0 5.2 -1.0 -0.9 -2.3 -0.9 -0.2 -0.6 0.2 -2.0 0.2 -1.0 -0.4 -0.5 0.7 -0.9 -0.6 -0.7
Respiratory disease 0.4 0.9 2.5 1.2 -1.4 0.1 -1.0 -1.4 -0.6 -1.1 -1.6 -1.0 -0.8 -1.0 0.1 0.9 0.2 0.5 -0.9
Type 2 Diabetes (T2D) (2018) 0.3 0.5 2.1 -0.4 -1.5 0.4 -1.0 0.4 0.1 1.1 0.2 0.5 -0.9 0.8 -0.7 -0.2 -0.4 0.9 -0.0
Lung FEV1/FVC ratio 0.8 4.1 10.5 -0.3 -0.8 -0.4 -2.9 2.1 -1.5 -1.5 0.8 -0.1 -2.8 1.5 -3.2 -3.1 -2.6 -2.4 -1.8
Lung FVC 0.5 2.5 9.4 -1.6 -0.5 -0.1 -0.2 1.5 -1.1 3.1 -1.0 1.8 -0.6 2.3 -0.8 -1.8 -0.9 -2.9 -1.4
Neuroticism 1.6 4.0 10.9 1.2 2.7 1.2 1.6 -0.1 2.6 1.8 1.3 0.4 1.9 -0.1 3.1 1.0 1.7 3.3 3.3
Chronotype (morning person) 0.4 1.0 3.7 -0.5 -0.7 0.1 -1.7 0.3 -1.1 0.1 -0.4 0.5 -1.7 0.6 -1.9 -0.3 -1.1 -0.5 -1.3
Hair Pigment 0.1 3.2 8.5 2.9 2.8 2.6 1.6 2.2 2.0 0.3 1.0 0.4 1.8 2.3 -1.0 -1.9 -0.1 -0.8 1.5
Tanning 0.1 1.5 4.3 -0.5 0.4 0.0 -0.9 -1.9 -1.2 -1.2 -1.0 -1.9 -1.2 -2.1 0.3 1.8 0.8 0.6 -1.2
Hand grip strength (left) 0.8 2.1 11.3 2.0 -0.3 -0.4 0.1 0.1 -1.9 -1.0 -1.8 -0.4 -0.3 -0.3 0.0 -1.9 0.5 -3.4 -2.3
Number of treatments/medications taken 0.4 0.7 2.0 0.4 -1.1 -0.3 -1.1 -1.3 0.3 -0.4 -0.6 -1.1 -1.0 -1.0 0.2 0.7 -0.2 1.4 0.5
Average weekly spirits intake 1.0 1.2 4.5 2.1 0.9 0.7 0.5 1.6 0.5 0.9 0.6 0.8 0.3 1.6 -1.1 -1.6 -0.7 -1.3 0.5
Sensitivity / hurt feelings 1.3 2.2 6.8 1.1 0.5 -0.1 -0.4 -2.4 0.4 -1.3 -1.4 -1.8 -0.1 -2.5 2.6 0.9 2.2 1.5 0.3
Frequency of depressed mood in last 2 weeks 1.0 1.4 3.8 1.4 2.0 1.4 1.0 0.3 1.2 1.9 1.2 0.3 1.2 0.0 1.7 -0.8 0.4 0.0 1.4
Hearing difficulty/problems: Yes 0.3 0.5 1.7 0.4 -1.1 0.4 -0.9 -0.5 -0.1 -1.1 1.3 -0.5 -0.7 -0.6 -0.6 -0.2 -0.6 0.7 0.2
Relative age of first facial hair 1.8 3.7 12.1 -1.9 0.7 -1.3 0.3 -3.5 0.2 -2.7 -2.9 -3.1 0.4 -3.0 1.5 1.9 1.0 0.3 -0.2
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 7.3 -1.4 -0.4 0.7 -0.2 -1.3 0.8 -1.6 -2.7 -0.6 0.1 -0.9 0.1 1.6 1.0 -0.1 -0.5
Ever used hormone-replacement therapy (HRT) 0.6 0.8 2.8 -1.6 -0.9 0.4 -1.0 0.2 -0.6 -0.9 -0.8 -0.1 -1.2 0.4 -1.7 0.3 -1.1 -0.1 -0.6
Ever had hysterectomy (womb removed) 2.0 2.3 6.8 -1.5 2.2 -0.5 1.8 0.5 2.3 0.6 1.2 0.5 1.8 0.7 1.8 -0.5 1.0 2.0 2.6
Systolic blood pressure, automated reading 0.7 2.0 7.8 2.6 0.8 0.5 2.8 0.1 2.1 0.4 -0.3 0.2 2.6 0.6 0.7 -0.1 1.2 0.4 1.6
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 3.4 1.4 -1.1 -0.2 -0.1 -0.5 -0.6 -1.7 -1.8 -0.6 -0.2 -0.7 -0.9 1.7 0.8 0.3 -1.2
Angina 0.5 0.6 3.1 1.8 -0.7 -1.2 -0.7 -0.4 -0.1 -0.6 -1.2 -0.1 -0.6 -0.4 0.2 0.9 0.5 0.9 -0.4
Medication for hormone replacement therapy 0.5 0.6 1.9 0.5 -0.8 -0.4 -0.7 0.2 -0.7 0.2 -0.8 -0.0 -0.8 0.7 -0.6 -1.2 -1.0 -1.4 -0.9
Vitamin and mineral supplements 1.0 1.4 3.8 1.9 0.5 0.2 1.3 1.9 1.5 -0.4 0.6 0.9 1.4 1.2 -1.3 -1.7 -0.5 -0.8 0.7
Supplements: Zinc 3.6 4.0 10.8 -1.6 -3.1 -1.7 -3.1 -0.9 -3.3 -1.0 -0.9 -0.6 -3.1 -0.8 -1.5 0.1 -1.3 -1.2 -3.1
Medication: Co-codamol 0.8 0.9 4.8 2.2 -1.1 1.0 -0.1 1.1 -0.3 1.3 0.4 1.2 -0.4 1.2 -1.0 -0.0 0.2 -0.8 -0.5
Medication: Metformin 0.8 1.1 2.4 -0.4 -1.0 1.0 -1.4 1.0 -0.4 1.3 1.1 1.0 -1.3 1.5 -1.5 -0.7 -1.1 0.5 -0.3
Diabetes (father) 0.6 0.7 3.3 0.8 0.4 1.1 0.5 0.4 0.7 0.1 1.7 0.6 0.8 0.2 0.4 -0.5 0.8 1.8 0.9
Diabetes (mother) 0.2 0.3 1.2 -0.8 0.4 0.3 0.0 0.6 0.3 -0.6 1.1 0.3 0.1 0.4 -0.5 0.1 -0.4 0.6 0.5
Severe depression (siblings) 3.8 4.3 11.1 0.6 1.1 -0.1 3.0 -2.0 2.5 -1.2 -0.7 -1.6 3.0 -2.4 3.3 1.3 3.2 1.0 1.9
Pack years adult smoking proportion 0.5 0.7 5.0 -1.1 -0.2 2.2 -1.1 0.1 -0.6 0.2 0.2 0.2 -0.9 0.8 -1.2 0.1 -0.7 0.7 -0.6
Impedance of leg (right) 0.8 4.1 9.1 -1.7 0.7 0.6 1.3 -2.6 1.5 -2.5 1.2 -2.3 1.3 -3.0 3.0 0.9 2.2 2.7 2.2
Leg fat-free mass (left) 0.3 1.9 6.6 2.6 1.4 1.1 0.4 1.2 0.1 0.8 -2.5 1.3 0.3 1.5 -1.0 0.0 0.6 -2.1 -1.2
Trunk fat percentage 0.6 2.5 9.1 1.6 3.0 1.1 1.4 -0.6 2.4 -1.8 0.6 -1.5 1.5 -1.1 0.7 0.3 1.3 1.7 2.1
Hand grip strength (right) 0.7 1.8 11.9 1.6 -0.0 -0.5 0.4 0.2 -1.4 -0.5 -2.1 -0.2 -0.2 0.0 -0.1 -1.8 0.4 -3.4 -2.0
Townsend deprivation index at recruitment 1.3 1.8 7.6 -0.5 -0.3 0.2 -0.3 -2.6 0.3 -1.8 -1.3 -2.8 -0.1 -2.0 0.9 1.8 0.8 0.5 0.2
Current tobacco smoking 0.6 1.0 7.5 -1.7 0.6 2.7 -0.1 -1.1 0.3 -0.6 -1.1 -1.0 0.0 -0.6 -0.3 0.5 0.6 0.6 -0.2
Average weekly fortified wine intake 1.2 1.5 4.7 -0.6 -0.6 -0.8 -1.0 2.1 -0.2 0.7 0.4 1.7 -0.9 1.9 -2.2 -0.5 -1.8 -0.7 -0.4
Maternal smoking around birth 2.7 3.9 14.6 1.5 2.7 2.5 1.5 -2.7 0.9 -2.0 -0.4 -3.8 1.4 -2.7 1.8 1.0 2.0 0.3 0.8
Fed-up feelings 1.1 2.0 5.1 -0.1 1.3 1.4 0.4 -1.5 1.4 -1.6 0.6 -1.8 0.8 -1.4 2.2 -0.5 1.2 2.2 1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 2.5 0.1 0.0 0.9 -1.1 0.3 -0.8 0.8 0.2 0.2 -0.8 0.3 -0.2 -0.6 -1.2 -1.6 -0.7
Relative age voice broke 1.2 1.9 5.9 -1.0 -2.2 -1.0 -0.9 -1.8 -1.3 -1.8 -2.4 -1.1 -1.0 -1.0 -0.4 0.2 -0.4 -1.3 -1.7
Taking other prescription medications 0.8 1.2 4.9 0.0 -1.0 -0.2 -0.6 -1.9 0.7 -1.0 -0.3 -1.0 -0.2 -1.6 0.5 1.8 0.3 2.2 0.7
Age when periods started (menarche) 0.4 1.1 3.1 0.1 -0.5 -0.4 0.2 -1.8 -0.4 -1.4 -1.7 -1.8 0.0 -1.3 0.8 -0.1 1.5 -0.3 -0.8
Bilateral oophorectomy (both ovaries removed) 0.8 1.0 6.7 -2.6 -0.3 -0.9 -0.5 0.9 0.3 -0.9 0.8 0.2 -0.6 0.6 -1.3 -1.0 -1.2 -0.2 0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 1.8 -0.5 0.8 -0.0 -0.5 0.9 0.2 0.6 1.4 0.4 -0.3 0.3 0.0 -1.0 -0.5 0.7 0.5
Tinnitus: Yes, but not now, but have in the past 0.9 0.9 7.1 0.8 -1.0 1.2 -1.2 0.3 -0.3 -0.6 0.2 -0.9 -1.1 0.3 -0.2 -2.7 -0.2 -0.1 -0.2
Qualifications: CSEs or equivalent 0.9 1.2 5.3 0.1 -0.8 0.3 -1.6 0.6 -1.4 0.2 0.1 -0.4 -1.8 0.4 -1.0 -2.3 -1.2 -1.0 -1.0
Serious illness, injury or assault to yourself 0.7 0.9 4.9 -0.9 -0.0 -0.3 0.5 -1.2 0.8 0.0 -0.6 0.6 0.8 -0.4 0.9 2.2 0.9 1.5 0.7
High blood pressure 0.3 1.0 5.8 2.4 -1.1 1.6 0.4 -0.6 0.8 -0.3 1.3 -1.0 0.2 -0.1 -0.4 0.1 0.5 0.9 0.9
Hayfever, allergic rhinitis or eczema 0.4 0.9 4.0 0.7 -1.8 -2.0 -0.7 0.4 -1.0 0.8 1.2 0.7 -0.9 0.2 -0.4 -0.1 -1.4 -0.3 -0.3
Multivitamins +/- minerals 0.7 0.9 2.3 -1.2 -0.9 -0.2 -0.9 -1.4 -0.9 1.1 0.5 -0.8 -1.0 -0.5 1.5 1.2 0.9 1.2 -0.1
Stomach or abdominal pain in last month 0.2 0.3 1.0 0.2 0.6 -0.5 -0.1 0.1 0.6 -0.1 0.7 0.5 0.1 -0.0 0.6 0.7 -0.0 1.0 0.9
Supplements: Glucosamine 0.4 0.5 1.5 -1.2 -0.5 0.3 -0.9 0.3 -0.6 0.3 -0.4 0.8 -1.0 0.7 -0.5 -0.4 -1.0 -1.1 -0.7
Diverticular disease/diverticulitis (self-reported) 0.9 1.1 3.9 0.3 1.9 2.0 0.5 -0.5 0.9 -0.7 -0.2 -1.8 0.6 -0.2 0.8 -0.8 1.1 1.1 0.8
Medication: Atenolol 1.1 1.4 7.5 0.9 -0.7 2.7 -1.4 -0.0 -0.8 -1.8 1.1 -1.0 -1.3 -0.1 -1.3 -1.0 0.1 0.1 -0.9
Medication: Levothyroxine sodium 1.6 2.7 8.3 -1.0 -1.8 -1.4 -1.7 1.5 -0.7 -0.2 -0.3 0.9 -1.7 1.2 -2.5 -2.5 -2.9 -2.4 -0.8
Sitting height 0.1 0.6 5.5 0.5 -0.4 0.0 -0.2 -0.5 -0.4 -0.2 -2.4 0.5 -0.3 0.1 0.2 0.7 1.1 -0.5 -1.1
Chronic bronchitis/emphysema (father) 0.4 0.5 2.5 0.2 0.3 1.6 0.2 0.2 -0.8 -0.0 -0.8 1.3 -0.0 0.2 0.6 -0.1 1.1 0.1 -0.5
High blood pressure (mother) 1.2 1.7 6.5 2.5 0.3 0.8 0.2 1.9 0.5 0.8 1.7 1.5 0.3 1.8 -0.4 -2.3 -0.2 -0.8 0.4
Body mass index (BMI) 0.8 3.6 11.3 1.6 2.1 1.0 0.1 3.4 1.5 1.9 2.2 1.8 0.4 3.0 -2.0 -2.5 -1.8 -0.3 1.4
Impedance of leg (left) 0.8 3.8 9.0 -1.6 0.9 0.7 0.9 -2.5 1.2 -2.6 1.2 -2.3 0.9 -3.0 2.8 0.8 2.0 2.9 1.9
Leg predicted mass (left) 0.3 1.8 6.5 2.6 1.4 1.1 0.5 1.2 0.2 0.8 -2.5 1.4 0.4 1.5 -0.9 0.0 0.6 -2.0 -1.1
Trunk fat mass 0.4 1.6 8.2 2.0 2.9 1.3 1.1 0.2 2.0 -1.0 -0.1 -0.6 1.2 -0.2 0.1 -0.1 1.1 0.9 1.4
Waist circumference 0.4 1.4 7.1 2.7 1.3 1.4 0.5 1.7 1.5 0.3 0.4 0.7 0.7 1.5 -1.4 -0.8 -0.1 0.2 0.8
Number of incorrect matches in round 0.6 0.9 2.6 -0.6 0.3 -1.1 1.1 1.3 1.6 0.9 0.3 0.8 1.1 1.1 0.3 -1.4 0.0 -0.4 1.2
Past tobacco smoking 1.4 2.6 8.5 -0.5 -0.8 -0.3 -1.3 2.5 -1.2 0.8 1.4 1.6 -1.4 2.2 -1.7 -2.9 -2.2 -1.4 -0.8
Alcohol usually taken with meals 1.4 2.3 5.6 -2.1 -0.8 -0.8 -1.2 -1.4 -2.2 -1.7 -2.3 -0.5 -1.2 -1.6 0.2 1.9 0.7 -0.5 -2.4
Nervous feelings 0.3 0.5 3.0 1.7 0.3 0.9 -0.1 -0.5 -0.2 0.2 1.0 -0.8 -0.1 -0.7 0.8 0.5 0.5 0.6 0.2
Frequency of tenseness / restlessness in last 2 weeks 3.6 5.6 17.3 1.5 4.2 2.3 3.1 -0.9 3.3 0.5 0.9 -0.5 3.4 -1.0 3.5 1.1 2.3 1.3 3.3
Hearing difficulty/problems with background noise 0.5 0.8 3.7 1.1 -1.5 -1.9 -0.7 -0.5 -0.7 -0.8 1.1 0.2 -0.7 -0.9 -0.5 0.8 -0.4 0.5 -0.3
Hair/balding pattern: Pattern 2 2.0 2.5 4.9 -0.2 2.2 1.1 2.2 -1.0 1.9 -0.6 0.9 -1.7 2.2 -1.3 2.2 -0.6 1.6 1.3 2.1
Had menopause 1.0 1.3 3.8 -1.7 -1.2 0.0 -1.5 1.2 -0.3 -0.4 0.5 0.9 -1.5 1.2 -1.9 -0.7 -1.4 -0.2 -0.4
Had other major operations 2.9 3.6 10.8 2.4 -1.8 0.6 -1.2 3.0 -0.1 1.7 1.7 2.7 -0.8 3.3 -2.2 -2.2 -1.9 0.1 0.1
Forced vital capacity (FVC) 0.5 1.9 6.2 1.6 0.8 -0.1 1.4 1.2 -0.2 2.2 -1.7 1.9 1.0 1.5 1.0 -1.0 0.9 -2.5 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 2.6 -0.1 -0.4 -0.1 -0.6 0.9 -0.2 0.3 1.4 -0.2 -0.6 0.0 -0.3 -1.6 -0.8 -0.2 0.1
Ever unenthusiastic/disinterested for a whole week 2.1 2.6 7.0 0.9 1.2 1.8 2.0 -0.7 1.8 0.3 0.2 0.3 2.1 -0.5 1.9 2.1 2.2 2.6 1.9
Qualifications: None of the above 0.4 0.9 4.1 -0.7 -0.8 0.6 -1.0 0.7 0.5 -0.0 0.8 -1.0 -0.9 0.5 -1.6 -2.0 -1.0 -0.9 0.1
Financial difficulties in last 2 years 0.3 0.4 1.2 1.0 0.2 0.8 -0.9 -0.4 -0.6 -1.1 0.5 -1.0 -0.7 -0.7 -0.1 -0.4 -0.3 -0.5 -0.4
Mouth/teeth dental problems 0.5 0.8 2.1 -1.1 0.4 -1.4 0.6 -0.9 -0.7 -0.8 -1.3 0.4 0.3 -1.1 0.7 1.2 0.5 -1.2 -0.8
Heart attack 0.2 0.3 1.1 0.4 -0.0 0.9 -1.0 0.2 -0.6 0.0 -0.0 0.4 -0.9 0.1 -0.2 0.7 0.1 0.6 -0.7
Allergy 0.3 0.7 3.2 -0.7 1.8 1.6 0.9 0.5 0.8 0.2 0.0 -0.2 1.0 0.4 0.1 -0.6 0.3 -0.6 0.5
Pain all over the body in last month 0.4 0.4 1.8 -0.6 0.2 1.3 -0.8 0.4 -0.0 0.1 1.0 -0.0 -0.6 0.4 0.1 -1.0 -0.4 0.9 0.3
Diabetes (self-reported) 0.3 0.4 2.8 0.7 -1.7 -0.6 -0.3 -0.1 0.5 0.6 0.2 -0.1 -0.1 0.1 -0.5 0.3 0.1 1.3 0.3
Hayfever/allergic rhinitis (self-reported) 1.5 1.9 10.1 -0.1 -2.7 -3.2 -1.1 -0.2 -1.5 0.2 0.2 0.2 -1.4 0.1 -0.7 0.3 -1.7 -1.8 -1.0
Medication: Ramipril 0.6 0.8 2.3 -0.7 -0.7 -0.2 -1.2 0.3 -1.0 1.0 1.3 0.1 -1.4 0.6 -1.2 -0.3 -1.5 -0.6 -0.6
Medication: Simvastatin 0.2 0.4 2.2 0.2 -0.4 0.9 -0.2 0.0 0.4 -0.2 1.2 -0.5 0.1 0.1 -0.0 0.0 0.0 1.5 0.8
Fluid intelligence score 0.3 0.5 3.7 -0.1 -1.0 -1.9 0.6 -1.0 0.2 -0.6 -0.4 -0.7 0.5 -0.5 0.8 0.2 0.1 0.3 0.4
Illnesses of siblings 0.6 0.9 8.3 -2.9 1.5 1.0 -0.2 -0.2 -0.4 0.6 0.8 -0.1 -0.1 -0.5 0.7 -0.5 -0.1 0.6 0.1
Neuroticism score 1.1 2.3 8.7 1.7 1.4 1.1 0.7 -1.3 1.5 0.1 0.1 -1.0 1.0 -1.3 3.0 0.7 1.9 2.4 1.9
Weight 0.3 1.5 5.3 2.3 2.3 1.2 0.7 1.5 1.3 0.4 -0.7 1.2 0.9 1.4 -0.9 -0.6 0.2 -0.6 0.4
Impedance of arm (right) 2.7 12.8 42.1 -0.7 0.1 -1.3 1.8 -6.3 0.5 -5.1 -2.2 -5.1 1.5 -6.5 4.1 4.4 4.2 1.9 0.5
Arm fat percentage (right) 0.3 1.0 5.2 1.3 2.3 0.5 0.9 0.7 1.8 -0.3 0.8 -0.4 1.1 0.4 -0.5 -0.6 -0.1 0.1 1.5
Trunk fat-free mass 0.5 2.8 7.1 2.2 0.3 0.8 -0.3 1.9 -0.6 1.7 -2.7 2.5 -0.4 2.6 -1.6 -0.5 -0.0 -2.5 -1.9
Hip circumference 0.2 0.8 5.4 0.8 2.3 0.3 0.7 1.3 1.0 0.5 -0.5 1.2 0.8 1.1 -0.6 0.0 -0.1 -0.4 0.4
Time employed in main current job 0.6 0.7 1.5 -1.2 -0.0 -1.1 -0.8 1.1 -0.7 -0.4 0.8 1.0 -1.1 0.5 -0.9 -0.7 -0.6 -0.5 -0.5
Alcohol intake versus 10 years previously 0.2 0.3 1.2 0.6 -0.5 -0.1 -0.5 0.2 -0.3 0.7 0.8 1.1 -0.5 0.3 0.0 0.5 -0.2 0.2 0.0
Father’s age at death 0.4 0.5 2.9 -0.2 0.6 1.0 0.3 1.0 0.4 0.7 0.5 1.7 0.4 1.1 -0.4 0.4 -0.1 0.1 0.3
Worrier / anxious feelings 0.1 0.2 0.7 -0.7 0.3 0.5 -0.8 0.0 -0.2 0.1 0.0 0.3 -0.7 -0.5 0.5 -0.1 0.1 0.2 -0.0
Frequency of tiredness / lethargy in last 2 weeks 1.2 1.9 8.0 1.2 1.8 2.8 -0.0 -2.1 -0.0 -0.7 -0.6 -1.5 0.2 -1.9 2.0 0.9 1.5 0.1 -0.1
Falls in the last year 1.5 2.1 7.3 2.1 1.1 1.2 1.8 0.3 2.7 0.5 1.4 -0.5 2.2 0.2 0.9 -0.6 0.6 1.1 2.4
Hair/balding pattern: Pattern 3 2.0 2.9 6.6 0.9 -1.1 0.7 -1.6 2.4 -1.4 1.4 0.9 2.5 -1.7 2.3 -2.6 -1.4 -2.0 -1.5 -1.4
Number of live births 0.6 0.8 3.9 0.0 0.2 1.0 0.2 0.8 0.8 0.1 2.0 -0.5 0.3 0.3 -0.3 -1.9 -0.8 -0.7 1.0
Forced expiratory volume in 1-second (FEV1) 0.7 2.5 11.4 1.5 0.3 -0.1 0.1 2.0 -1.0 1.8 -1.1 1.9 -0.2 2.0 -0.2 -2.4 -0.3 -3.4 -1.5
Pulse rate 0.7 1.2 3.8 2.0 0.5 -1.8 0.2 1.4 0.8 1.3 0.6 1.3 0.6 1.5 -0.8 -0.8 -1.2 -0.1 0.9
Happiness 2.1 2.5 6.6 -0.9 1.6 0.9 1.5 -1.0 2.1 1.0 0.8 -0.4 1.7 -0.4 2.4 1.7 1.6 2.6 2.4
Noisy workplace 0.2 0.3 2.0 -0.5 0.3 1.4 -0.1 0.4 0.9 -0.3 0.4 0.2 -0.1 0.3 -0.9 -0.2 -0.2 0.4 0.5
Qualifications: A levels/AS levels or equivalent 0.7 1.5 4.0 0.2 -0.6 -1.3 0.2 -1.9 -1.0 -2.0 -0.9 -1.4 0.3 -1.9 1.2 1.7 1.3 0.2 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.8 -1.4 0.1 -0.4 0.1 -0.3 -0.0 -1.0 0.5 -0.6 0.2 -0.4 0.4 0.2 -0.6 0.6 0.5
Mouth/teeth dental problems: Dentures 1.4 2.4 6.7 1.0 -0.5 2.2 0.1 2.0 0.9 2.5 2.0 1.3 0.0 2.6 -1.2 -1.6 -1.0 1.3 1.2
Asthma 0.4 0.9 4.7 1.0 0.2 0.6 0.2 -1.2 0.7 -0.6 -0.3 -0.4 0.3 -0.8 1.1 0.6 1.6 2.2 0.6
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.4 0.8 -0.7 0.3 -0.8 0.5 -0.2 -0.3 -0.0 0.1 -0.7 0.6 -0.1 -1.6 -0.6 -1.1 -0.4
Medication: Cholesterol lowering 0.8 1.3 5.1 1.6 -1.7 1.6 -0.6 0.5 -0.2 1.2 1.2 0.4 -0.5 1.0 -0.8 1.5 0.1 2.3 0.2
Depression (self-reported) 0.8 0.9 3.0 -0.2 1.5 0.1 1.1 0.3 1.7 0.1 0.7 0.5 1.3 0.0 1.3 0.2 0.2 1.1 1.7
Medication: Lansoprazole 0.5 0.6 3.8 -0.5 -1.2 -0.8 -0.1 0.6 -0.0 2.0 -0.3 1.1 -0.2 1.0 -0.5 0.4 -0.6 -0.2 -0.2
Prospective memory result 1.8 2.2 6.6 0.2 1.5 1.5 1.1 1.6 1.8 2.6 1.3 2.3 1.1 1.5 0.8 -0.3 0.6 1.9 1.7
Lung cancer (father) 2.1 2.4 7.3 0.3 2.7 1.3 2.5 -0.4 2.6 -0.8 0.7 -0.9 2.7 -0.7 0.9 0.4 1.1 0.8 2.1
Illnesses of mother 0.4 0.5 1.1 0.2 -0.1 0.5 -0.4 -0.9 -1.0 0.1 -0.5 -0.6 -0.6 -0.6 0.1 0.7 1.1 1.0 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 3.0 11.8 1.4 -0.4 -0.2 -0.8 1.8 -2.2 2.0 -1.5 2.1 -1.2 1.9 -0.7 -1.3 -0.7 -3.4 -2.6
Pulse wave Arterial Stiffness index 3.1 3.6 10.3 2.5 -0.5 0.6 -1.3 2.9 -0.3 3.2 2.3 1.9 -1.1 2.8 -1.6 -2.1 -2.2 -0.5 0.2
Impedance of arm (left) 3.1 14.2 46.0 -1.1 1.1 -1.0 2.2 -6.5 0.8 -5.0 -2.4 -5.2 1.9 -6.8 4.3 4.9 4.5 2.4 0.7
Arm fat mass (right) 0.3 1.2 4.8 1.6 2.2 0.8 0.5 1.5 1.4 0.5 0.4 0.6 0.6 1.3 -1.1 -0.9 -0.6 -0.5 0.9
Trunk predicted mass 0.5 3.0 7.7 2.2 0.3 0.8 -0.4 1.9 -0.6 1.7 -2.8 2.6 -0.5 2.6 -1.6 -0.4 -0.1 -2.6 -1.9
Standing height 0.8 7.8 38.7 2.2 1.1 0.5 1.6 -3.6 -0.1 -3.0 -6.2 -1.3 1.3 -2.9 2.4 3.8 4.4 -0.9 -2.0
Length of working week for main job 0.9 1.0 2.8 0.2 -1.3 -0.6 -0.3 0.8 -0.9 1.1 -0.7 1.0 -0.4 1.2 -1.4 -0.2 -1.2 -1.7 -1.2
Exposure to tobacco smoke at home 1.0 1.1 3.9 -1.0 1.4 -0.0 1.5 0.7 2.0 0.7 1.0 0.7 1.4 0.7 -0.3 -0.0 -0.4 0.1 1.9
Breastfed as a baby 3.0 3.7 13.3 0.7 -0.5 0.8 -1.7 2.8 -2.4 2.1 0.7 3.7 -1.9 3.0 -1.8 -1.1 -1.3 -0.9 -2.0
Tense / ‘highly strung’ 0.4 0.7 2.1 0.3 0.7 0.5 0.4 0.1 1.0 1.4 1.4 0.6 0.4 0.2 1.5 -0.1 0.2 0.5 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 2.5 3.7 17.1 0.0 1.0 0.7 1.2 -1.7 2.5 -0.7 1.2 -1.3 1.7 -1.3 2.9 1.3 1.9 4.1 3.0
Hair/balding pattern: Pattern 4 0.3 0.7 3.3 -0.7 -1.0 -1.8 -1.4 -0.4 -0.7 -0.4 -0.2 0.1 -1.2 -0.5 0.1 1.2 -0.1 0.3 -0.6
Birth weight of first child 1.5 2.8 19.3 -1.6 4.4 2.5 0.6 -1.6 0.3 -1.4 -2.0 -1.5 0.7 -1.2 0.6 0.9 1.2 -0.0 -0.3
Peak expiratory flow (PEF) 0.6 1.5 8.0 1.1 1.2 -0.4 0.7 1.4 -0.4 0.6 -0.6 0.4 0.3 1.2 0.2 -2.8 -0.1 -2.7 -0.7
Pulse wave reflection index 1.0 1.2 5.6 0.8 -0.1 2.4 0.1 1.4 0.1 1.3 1.9 0.3 0.1 1.2 0.1 -1.8 -0.4 -0.0 0.5
Ever highly irritable/argumentative for 2 days 1.4 1.6 5.7 1.6 0.0 2.4 1.3 -0.2 1.2 -0.0 1.0 -0.7 1.4 -0.1 1.1 0.9 1.8 2.1 1.1
Loud music exposure frequency 1.8 2.0 6.5 -0.6 -1.2 0.0 0.1 -2.1 -0.4 -2.2 -1.8 -1.4 -0.0 -2.5 0.9 2.2 1.2 -0.8 -0.9
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 3.0 1.7 -1.3 -0.8 0.4 -1.0 -0.8 -1.0 -0.6 -0.3 0.4 -1.0 0.6 1.0 0.8 -0.2 -0.8
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 2.9 -0.2 1.0 1.7 -1.0 -1.2 -0.5 -1.1 -0.1 -1.3 -0.7 -0.9 0.4 0.2 0.4 0.7 -0.3
Blood clot in the leg (DVT) 0.2 0.3 1.4 -0.3 -0.5 0.1 -0.4 0.3 0.0 -0.6 0.3 0.8 -0.4 0.5 -1.2 0.0 -0.0 1.0 -0.2
Medication: Paracetamol 0.2 0.3 2.0 0.1 0.6 0.8 -0.4 0.4 0.3 0.2 -0.6 0.3 -0.6 0.6 0.1 -1.4 -0.1 0.5 0.4
Headache pain in last month 0.4 0.6 2.0 1.4 1.0 0.2 0.8 -0.6 0.7 -0.7 0.6 -0.5 0.8 -0.8 1.3 0.1 0.7 0.1 1.0
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 4.3 -2.1 1.8 -1.5 -0.2 0.1 -0.9 -0.8 -1.1 0.2 -0.2 -0.5 0.3 -1.1 -0.5 -1.6 -1.0
Glaucoma (self-reported) 0.5 0.6 3.4 1.1 0.6 1.9 0.8 -0.7 0.6 0.4 0.4 -0.4 0.9 -0.3 1.0 0.3 0.6 -0.3 0.6
Gout (self-reported) 0.9 1.3 4.0 0.9 -0.7 -0.5 -0.7 1.3 -0.7 0.5 -1.3 0.8 -0.8 1.5 -1.3 -1.6 -0.8 -2.0 -1.2
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 8.1 -1.1 -1.1 -2.8 -0.3 0.0 0.0 -0.5 -1.8 0.1 -0.4 -0.4 -0.7 -0.1 -1.3 -1.6 -0.3
Medication: Amlodipine 0.6 0.8 4.8 2.2 -1.0 0.8 0.2 0.9 0.3 0.9 1.5 1.2 0.2 1.0 -0.4 0.2 0.1 0.3 0.4
Medication: Ventolin 100micrograms inhaler 0.7 0.9 4.0 -1.0 -1.1 -0.3 -0.2 -1.3 0.0 -1.2 -1.2 -0.6 -0.3 -1.0 0.8 0.9 0.9 2.0 0.1
Birth weight 0.9 1.9 4.6 0.9 1.9 1.7 2.0 -0.9 1.7 -0.3 -1.4 -0.9 1.9 -0.8 1.1 1.2 2.1 0.4 1.0
Chronic bronchitis/emphysema (mother) 1.7 2.0 5.1 0.7 1.5 0.2 1.4 -1.8 1.5 -1.5 -0.2 -2.3 1.5 -1.9 1.7 0.7 1.5 1.1 1.3
High blood pressure (siblings) 0.4 0.6 4.0 2.0 -1.2 -0.6 -0.1 0.8 0.0 -0.2 -0.7 0.4 -0.2 0.9 -1.3 -0.3 -0.3 -0.6 -0.5
Forced vital capacity (FVC), Best measure 0.7 2.7 9.3 1.4 -0.1 -0.1 -0.2 1.7 -1.8 2.5 -1.6 2.6 -0.6 2.0 -0.3 -0.9 -0.3 -3.0 -2.1
Body fat percentage 0.5 1.8 7.8 1.3 2.8 1.2 1.0 0.6 2.3 -0.9 1.4 -0.7 1.2 0.0 -0.1 -0.7 0.3 1.3 2.1
Leg fat percentage (right) 0.9 3.4 9.0 0.6 2.6 1.5 0.4 2.6 2.4 0.8 3.0 0.9 0.7 2.0 -0.8 -2.7 -1.2 1.1 2.6
Arm fat-free mass (right) 0.6 2.9 9.1 2.1 1.2 1.8 0.0 2.7 0.4 2.0 -1.3 2.7 0.0 3.0 -1.5 -1.3 -0.3 -1.5 -0.6
Exposure to tobacco smoke outside home 2.2 2.9 6.9 1.9 2.6 0.5 2.2 -1.1 2.2 -0.5 0.7 -1.9 2.5 -1.5 1.6 0.5 1.7 1.2 2.1
Comparative body size at age 10 0.9 2.6 9.1 -0.8 2.6 1.6 0.3 2.1 0.5 3.0 1.3 1.6 0.3 2.1 -0.5 -2.0 -1.6 -1.4 0.8
Number of full brothers 2.6 3.3 14.6 3.8 1.5 2.6 1.9 0.7 2.1 0.7 1.6 0.1 2.2 0.4 1.3 -1.1 1.7 1.4 2.0
Worry too long after embarrassment 1.5 2.6 6.2 1.8 1.7 0.8 1.4 -1.7 1.5 -0.2 -0.6 -1.1 1.5 -1.9 2.5 2.1 2.1 1.4 1.6
Seen a psychiatrist for nerves, anxiety, tension or depression 2.3 3.0 9.0 -0.4 1.4 0.8 1.8 -1.0 3.0 -0.4 -1.0 -0.5 2.2 -0.7 2.7 1.3 1.9 2.5 2.6
Wheeze or whistling in the chest in last year 0.7 1.3 3.4 -0.1 0.9 0.6 0.3 -1.8 1.1 -1.4 -1.0 -1.8 0.5 -1.4 0.8 0.7 1.3 1.6 0.8
Number of children fathered 0.6 0.7 5.8 -0.3 0.4 -1.3 0.1 0.7 0.5 0.1 -0.3 -0.0 0.2 0.5 -0.4 -2.4 -0.7 -1.2 0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.4 1.6 -0.3 -1.3 0.3 0.1 -0.8 0.5 1.1 -0.1 -0.6 -0.1 -0.0 0.5 0.3 0.5 1.2 0.6
Age at first live birth 0.6 1.1 4.4 -0.3 0.3 -1.0 -0.3 -0.3 -1.9 -1.0 -1.8 0.7 -0.4 -0.8 -0.0 1.6 0.8 -0.4 -2.1
Pulse wave peak to peak time 3.6 4.3 12.1 -2.2 0.5 -0.8 1.4 -3.1 0.5 -3.5 -2.7 -1.9 1.3 -3.0 1.9 2.5 2.5 0.7 -0.1
Health satisfaction 0.4 0.5 1.9 0.7 -0.5 0.8 -0.4 -0.9 0.4 -1.4 0.7 -0.6 -0.2 -1.1 0.4 0.7 0.4 0.6 0.4
Shortness of breath walking on level ground 0.5 0.6 2.4 1.2 -1.6 -1.1 -0.7 0.4 -0.3 0.1 -0.5 0.1 -0.8 0.5 -0.8 -0.2 -0.5 -0.8 -0.6
Qualifications: College or University degree 0.5 1.6 4.6 -1.1 0.3 -0.6 1.0 -1.9 0.6 -0.9 0.0 -0.5 1.2 -1.8 2.2 1.8 1.5 1.6 0.8
Eye problems/disorders: None of the above 1.0 1.2 3.8 -1.3 1.0 -0.6 1.4 0.3 1.9 0.8 0.9 0.1 1.6 0.4 1.1 -0.9 0.1 0.5 1.9
Mouth/teeth dental problems: Loose teeth 1.0 1.2 7.2 1.9 0.5 2.7 -0.2 0.8 -0.3 0.4 1.5 -0.0 -0.1 0.6 -0.3 -1.6 0.3 1.3 0.2
Emphysema/chronic bronchitis 2.0 2.2 5.2 0.4 -2.2 0.1 -2.0 -0.5 -1.9 -0.7 -1.7 -1.5 -2.3 -0.0 -1.1 -0.9 -0.8 -2.1 -2.2
Medication for pain relief, constipation, heartburn 0.2 0.4 2.3 -1.5 0.0 -0.2 0.2 0.7 -0.1 0.1 -0.5 0.0 0.5 0.7 -1.1 -0.1 -0.6 -0.7 -0.6
Neck or shoulder pain in last month 1.7 2.4 8.2 0.7 -0.1 2.9 -0.8 1.7 -0.7 1.6 2.5 0.8 -0.8 2.1 -1.7 -2.4 -1.5 -0.0 -0.2
Medication: Blood pressure 0.5 0.9 4.0 1.6 -2.0 0.9 0.4 -0.6 0.8 0.3 0.6 0.0 0.3 0.2 0.4 1.3 0.9 1.3 0.8
Angina (self-reported) 0.5 0.6 2.7 1.6 -0.8 -1.2 -0.9 -0.3 -0.2 -0.5 -1.2 -0.0 -0.8 -0.2 -0.1 0.9 0.2 0.7 -0.5
Migraine (self-reported) 0.6 0.8 4.8 0.2 2.2 1.2 0.9 -0.5 0.9 -0.9 -0.4 -0.8 0.9 -0.5 0.5 -0.8 0.4 -0.1 0.8
Medication: Ibuprofen 0.7 0.8 3.5 1.5 -0.8 0.7 -1.0 0.8 -0.2 0.1 -0.0 -0.1 -0.9 1.0 -0.5 -1.9 -0.9 -1.2 -0.4
Medication: Allopurinol 0.9 1.1 4.3 0.4 0.3 0.7 -0.1 1.9 0.2 1.1 0.0 1.5 -0.1 2.1 -1.3 -1.8 -0.7 -0.7 -0.1
Medication: Omeprazole 0.5 0.5 2.5 0.1 0.2 -1.1 0.3 -1.3 0.6 -0.9 -0.4 -0.7 0.2 -1.6 0.5 0.8 -0.2 -0.6 0.5
Medication: Seretide 50 evohaler 1.0 1.1 4.9 1.8 -0.2 0.0 -0.1 0.9 0.0 1.4 2.2 -0.0 -0.2 1.1 0.4 -2.2 0.2 1.0 0.6
Mean time to correctly identify matches 1.0 1.8 12.1 -0.4 0.3 -0.5 0.1 -1.7 0.6 -1.7 -0.6 -1.4 0.2 -2.1 -0.0 3.5 0.8 1.8 0.4
Heart disease (mother) 0.7 0.9 3.6 -0.0 -1.9 -1.2 0.2 0.5 1.2 -0.9 0.9 -0.3 0.4 0.1 -0.8 -0.8 -1.2 -1.2 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 6.5 -1.5 0.6 -0.6 -0.3 1.1 0.5 -0.1 1.3 -0.2 -0.4 0.8 -0.3 -2.6 -0.7 -0.3 0.5
Whole body fat mass 0.4 1.6 8.4 1.9 2.9 1.5 0.9 1.2 2.0 -0.2 0.6 0.3 1.1 0.8 -0.5 -0.8 0.2 0.5 1.5
Leg fat mass (right) 0.8 2.9 7.9 1.4 2.8 1.7 0.5 2.7 2.1 1.1 1.8 1.5 0.8 2.3 -1.1 -2.0 -0.7 0.3 1.8
Arm predicted mass (right) 0.5 2.5 7.2 2.0 1.4 1.8 0.0 2.3 0.2 1.7 -1.7 2.2 0.0 2.7 -1.5 -1.1 -0.2 -1.7 -0.9
Pulse rate, automated reading 2.8 9.1 29.1 2.5 -0.6 1.9 -1.2 4.6 0.0 3.0 3.0 2.8 -1.0 5.4 -4.1 -4.6 -4.1 -1.6 0.4
Alcohol intake frequency. 0.3 0.6 7.5 2.7 -0.3 -0.2 -0.4 0.6 -0.5 -0.5 0.4 0.0 -0.1 -0.3 0.3 -0.7 -0.2 0.0 -0.3
Comparative height size at age 10 0.4 2.4 6.3 2.5 0.9 0.6 2.1 -1.1 0.8 -0.7 -2.3 -0.7 2.0 -1.2 1.6 2.2 2.4 -0.2 -0.2
Number of full sisters 0.2 0.3 1.3 -0.7 0.3 0.7 0.6 -0.4 0.2 0.3 -0.4 -0.1 0.5 -0.6 1.1 0.1 0.9 0.1 0.1
Suffer from ‘nerves’ 0.3 0.5 2.5 1.6 -0.7 0.6 -0.9 -0.5 -0.9 -0.0 0.9 -0.7 -1.0 -0.8 0.0 0.5 -0.2 -0.1 -0.5
Overall health rating 0.2 0.4 1.3 0.6 -0.2 -0.1 -1.2 -0.3 -0.6 0.4 0.0 0.5 -1.1 0.0 -0.8 0.6 -0.9 -0.6 -0.7
Chest pain or discomfort 0.9 1.2 5.1 2.2 -1.5 -0.2 -1.6 0.2 -1.3 -0.8 0.6 -0.3 -1.6 0.0 -1.3 -0.3 -1.0 -0.7 -1.1
Had major operations 0.7 0.8 2.3 0.7 -0.2 -0.7 1.5 -0.5 1.4 0.5 -0.2 0.5 1.5 -0.0 1.4 0.5 1.1 0.6 1.0
Age at last live birth 0.5 0.7 2.0 -1.1 -0.1 -1.3 0.6 -0.4 -0.8 -1.1 -0.8 -0.2 0.5 -0.9 0.7 0.3 0.6 -1.4 -1.0
Family relationship satisfaction 0.2 0.2 1.4 -1.2 -0.1 -0.2 0.3 0.2 0.7 0.3 0.2 0.2 0.4 0.3 0.4 0.6 -0.2 0.5 0.7
Leg pain on walking 0.9 1.1 3.1 1.6 -1.0 1.6 0.4 1.7 0.5 0.8 1.0 1.2 0.3 1.8 -0.8 -1.2 -0.3 0.2 0.5
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 2.3 1.4 1.4 1.5 1.1 0.2 0.6 1.2 -0.5 0.3 1.0 0.5 0.7 1.2 0.4 0.5 0.7
Commuting to job workplace: Car/motor vehicle 2.2 2.5 14.3 0.7 3.8 2.3 1.5 -0.2 1.3 -0.7 0.3 -1.0 1.4 -0.6 1.5 -0.7 1.7 1.8 1.5
Illness, injury, bereavement, stress in last 2 years 0.6 0.8 3.1 -1.0 -0.0 -1.1 -0.1 -0.5 -1.1 -0.4 -1.7 0.0 -0.4 -0.7 -0.3 0.5 -0.0 -1.4 -1.5
Medication: Aspirin 0.7 0.9 2.8 0.8 -1.6 -1.0 -0.6 -1.5 -0.5 -0.4 0.2 -0.5 -0.8 -1.3 0.8 1.7 0.8 1.0 -0.2
Supplements: Vitamin C 0.3 0.4 3.0 0.5 -0.5 1.7 -0.7 -0.2 -0.9 0.2 0.3 0.1 -0.7 -0.2 -0.2 0.0 -0.2 -0.3 -0.6
Knee pain experienced in last month 0.5 0.8 2.8 1.4 1.7 0.9 0.6 0.8 1.1 0.5 0.8 0.1 0.8 0.7 -0.4 -1.1 -0.3 0.3 1.0
Hypertension (Self-reported) 0.3 0.9 3.8 1.9 -1.5 1.4 -0.1 -0.7 0.7 -0.8 1.3 -1.3 -0.3 -0.2 -0.6 -0.1 0.2 0.8 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 2.4 -1.1 0.4 0.4 0.9 -0.1 1.2 0.8 1.3 -0.3 0.9 -0.4 0.8 -0.4 -0.6 0.3 1.5
Illnesses of father: Heart disease 1.7 2.4 7.3 1.2 -2.7 -1.2 -1.9 1.8 -1.4 1.0 -0.1 1.5 -1.9 1.8 -1.3 -1.9 -1.4 -0.7 -1.2
Illnesses of siblings: Diabetes 0.5 0.6 3.1 1.1 -0.6 0.1 -1.1 -0.5 -0.6 -1.8 0.5 -0.4 -1.2 -0.7 -0.5 0.2 -0.3 0.4 -0.3
Smoking status: Previous 1.1 1.6 6.2 1.1 0.2 -0.5 0.9 -1.8 1.1 -0.7 -1.2 -1.3 1.0 -1.7 1.3 2.5 1.7 1.0 0.6
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.2 7.5 2.1 0.7 0.8 0.3 -1.7 -0.9 -1.4 -2.7 -1.8 0.0 -1.6 0.7 1.5 2.0 -0.9 -1.7
Whole body fat-free mass 0.4 2.5 6.9 2.5 0.8 1.1 -0.0 1.8 -0.2 1.5 -2.6 2.2 -0.1 2.3 -1.4 -0.4 0.2 -2.3 -1.6
Leg fat-free mass (right) 0.4 2.0 7.9 2.7 1.2 1.1 0.2 1.1 -0.3 0.9 -2.8 1.5 0.1 1.5 -1.0 0.3 0.7 -2.0 -1.6
Arm fat percentage (left) 0.3 1.3 7.5 1.1 2.7 0.8 1.0 0.5 1.9 -0.5 0.8 -0.7 1.2 0.0 -0.3 -0.3 0.1 0.5 1.6
Average weekly red wine intake 0.9 1.4 4.5 -1.0 -0.1 1.1 -0.7 1.6 -1.3 2.1 0.1 2.1 -0.9 1.7 -0.7 -0.7 -0.7 -0.1 -1.0
Handedness (chirality/laterality): Left-handed 2.9 3.5 8.7 0.6 -1.0 1.0 -1.7 2.8 -1.9 2.4 0.4 2.4 -1.7 2.9 -2.1 -2.2 -1.7 -0.9 -1.5
Mood swings 3.0 5.4 14.3 -0.3 3.3 1.6 2.1 -2.1 2.8 -1.0 -0.3 -1.5 2.5 -1.9 3.8 0.9 2.9 3.2 3.0
Loneliness, isolation 0.3 0.4 1.2 0.8 -1.0 0.0 -1.1 -0.7 -0.1 -0.6 0.1 -0.9 -0.7 -0.8 0.6 -0.3 0.4 0.8 -0.2
Long-standing illness, disability or infirmity 0.4 0.6 1.6 0.2 -1.3 0.6 -1.1 -1.1 -0.1 -0.1 -0.9 -0.6 -0.9 -0.4 -0.3 1.1 -0.1 1.2 -0.2
Ever had bowel cancer screening 0.7 0.8 2.7 -0.7 0.0 1.3 -0.4 0.9 0.4 1.4 1.0 1.0 -0.4 1.6 -0.9 -0.1 -0.9 1.1 0.7
Diabetes diagnosed by doctor 0.6 1.0 7.0 0.4 -2.6 -0.3 -1.6 -0.1 -0.7 0.2 -0.2 -0.0 -1.5 0.1 -1.3 0.5 -0.4 0.7 -0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.6 1.9 1.2 -0.5 0.4 0.4 0.6 -0.5 1.3 0.0 1.3 0.2 1.1 -0.1 -0.3 -0.2 -1.4 -0.5
Friendships satisfaction 0.5 0.6 1.9 -0.7 0.2 -0.5 0.4 0.3 0.9 1.4 1.2 0.2 0.6 0.4 1.2 -0.6 -0.3 0.6 1.3
Qualifications: nursing, teaching 2.0 3.2 6.4 -0.1 2.0 0.7 2.5 -1.6 1.1 -1.6 1.7 -0.7 2.5 -1.7 2.4 1.1 2.2 2.4 1.8
Commuting to job workplace: Walk 1.3 1.4 5.8 0.3 -2.4 -1.4 -1.1 -0.8 -0.8 -1.9 -1.1 -1.3 -0.8 -1.1 -0.9 0.5 -0.7 -0.8 -1.0
Eye problems/disorders: Cataract 0.9 1.0 3.3 -0.1 -0.9 0.1 -1.8 0.4 -1.4 -0.7 -0.8 -0.4 -1.7 0.0 -1.4 -0.8 -1.0 -0.5 -1.5
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 1.2 1.1 0.1 -0.4 0.2 -0.7 -0.1 -0.2 0.0 -0.6 0.2 -0.4 0.1 0.6 -0.1 -0.0 0.1
Medication for cholesterol 1.2 1.8 6.6 -0.3 1.2 0.4 2.6 -0.1 1.6 0.8 0.3 0.7 2.5 -0.2 2.0 1.0 1.6 0.9 1.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 7.6 -0.2 2.8 0.0 0.8 1.0 1.1 0.9 2.2 0.9 0.5 0.2 0.6 -0.7 -0.2 0.2 1.5
Back pain experienced in last month 0.3 0.5 1.9 0.5 -0.7 0.7 -0.4 0.6 0.3 1.1 0.1 0.4 -0.3 0.8 -1.4 0.3 -1.1 -0.9 -0.0
Mineral and other dietary supplements 0.5 0.6 2.5 0.9 0.7 1.6 1.2 0.3 0.8 -1.0 -0.2 -0.3 1.4 0.1 -0.4 -0.1 0.8 0.1 0.2
Breast cancer (self-reported) 0.3 0.4 2.3 1.5 -0.1 0.7 0.7 -0.2 0.7 -0.0 0.1 0.4 0.8 0.0 0.5 0.4 0.2 1.0 0.8
Asthma (self-reported) 0.3 0.6 3.9 0.7 0.2 0.7 -0.1 -1.1 0.6 -0.5 -0.0 -0.6 0.0 -0.6 0.9 0.2 1.2 2.0 0.6
Osteoporosis (self-reported) 0.3 0.4 2.3 -1.5 0.3 -0.1 0.2 -0.4 0.8 1.1 0.4 -0.9 0.0 -0.0 -0.1 -0.1 -0.4 -0.2 0.9
Osteoarthritis (self-reported) 0.2 0.2 0.9 0.1 0.2 1.0 -0.1 0.4 0.5 0.2 -0.9 -0.0 0.0 0.5 -0.8 0.1 -0.3 -0.6 -0.0
Medication: Aspirin 0.5 0.6 2.1 0.6 -1.4 -0.9 -0.5 -1.0 -0.3 0.1 0.6 -0.1 -0.6 -0.9 0.8 1.4 0.6 1.1 0.1
Medication: Gliclazide 0.4 0.5 1.8 0.1 -0.7 -0.2 -0.6 0.4 -0.4 1.3 0.2 1.3 -0.8 0.8 -0.5 0.8 -0.1 1.1 -0.0
Illnesses of father: None of the above (group 1) 0.8 0.9 5.1 -1.6 2.2 0.9 0.9 -0.7 1.0 -0.8 -0.5 -0.7 1.0 -0.6 0.2 1.1 0.4 -0.1 0.6
Smoking status: Current 0.8 1.3 7.7 -2.1 0.8 2.8 0.2 -1.5 0.6 -0.4 -0.9 -1.2 0.3 -0.8 0.1 0.9 0.9 1.0 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 5.9 -0.5 -0.4 -1.7 -0.6 1.4 0.0 1.3 0.6 0.7 -0.6 1.4 -0.8 -2.4 -1.5 -2.0 -0.2
Whole body water mass 0.5 2.6 7.3 2.4 0.8 1.1 -0.0 1.9 -0.3 1.6 -2.7 2.2 -0.1 2.4 -1.5 -0.4 0.1 -2.4 -1.6
Leg predicted mass (right) 0.4 2.0 7.9 2.6 1.2 1.0 0.2 1.1 -0.3 0.8 -2.8 1.4 0.2 1.4 -1.0 0.2 0.6 -2.1 -1.6
Arm fat mass (left) 0.3 1.3 6.7 1.3 2.6 1.0 0.6 1.5 1.6 0.4 0.4 0.6 0.8 1.3 -1.0 -0.7 -0.5 -0.3 1.1
Number of self-reported non-cancer illnesses 0.4 0.6 2.8 1.7 -1.3 0.6 -1.2 -0.3 0.1 -0.6 0.2 -0.6 -1.0 -0.1 -0.2 -0.5 -0.3 0.9 0.3
Average weekly champagne plus white wine intake 0.7 1.0 2.4 -1.0 -1.5 -0.5 -0.9 -1.3 -1.1 -0.9 -0.5 -1.1 -1.0 -0.9 -0.4 0.6 -0.5 -1.5 -1.2
Miserableness 0.5 0.9 4.5 0.5 1.2 0.9 0.3 -0.9 0.1 -0.4 -0.2 -0.9 0.5 -0.9 2.1 0.3 1.4 1.2 0.5
Guilty feelings 1.6 2.4 4.8 1.8 1.9 2.1 1.6 -0.8 1.6 -0.3 0.1 -0.2 1.9 -0.9 2.2 1.2 2.2 1.9 1.5
Wears glasses or contact lenses 1.2 1.4 3.5 1.9 1.2 1.6 1.4 1.0 1.6 0.0 1.0 0.7 1.7 0.8 0.4 -0.5 0.7 0.7 1.5
Ever taken oral contraceptive pill 2.5 2.8 6.6 1.4 2.1 2.6 1.9 -1.1 1.9 0.2 -0.4 -0.4 2.0 -0.9 1.9 1.5 2.5 1.9 1.6
Hearing aid user 1.5 1.7 6.3 1.9 -2.5 1.2 -1.5 0.1 -2.0 -0.6 -0.2 0.2 -1.5 0.1 -1.6 0.2 -0.4 -0.2 -2.1
Mother’s age at death 0.2 0.2 0.8 -0.8 0.5 0.5 0.2 0.0 -0.0 -0.7 0.5 -0.2 0.3 0.1 -0.1 0.2 -0.6 -0.9 0.0
Financial situation satisfaction 2.2 2.8 7.1 -1.8 1.8 0.0 0.6 -2.7 1.3 -1.4 -1.3 -2.6 0.7 -2.5 2.3 1.6 1.5 0.7 1.2
Tinnitus: Yes, now most or all of the time 0.5 0.6 3.4 0.3 -1.3 -1.8 -0.2 -0.1 -0.0 0.2 1.1 0.3 -0.2 -0.1 0.8 0.2 -0.1 1.4 0.6
Commuting to job workplace: Public transport 1.9 2.3 5.4 -0.9 -2.3 -0.5 -2.3 -1.0 -2.1 -1.0 0.7 -1.4 -2.3 -0.7 -1.7 0.4 -1.6 -1.2 -1.8
Eye problems/disorders: Glaucoma 0.6 0.7 4.2 0.6 1.1 2.0 0.7 -1.0 0.3 0.1 -0.2 -0.0 0.6 -0.5 1.1 1.0 1.1 -0.2 0.1
Medication: Blood pressure 0.8 1.5 6.0 0.4 -0.8 0.6 -2.4 -0.0 -1.3 -0.7 0.5 -0.8 -2.4 0.1 -2.2 -0.9 -1.1 -0.4 -1.3
Pain type(s) experienced in last month: Hip pain 2.2 2.8 5.6 2.4 2.1 0.8 1.6 1.9 1.9 2.2 2.1 1.1 1.6 1.9 0.7 -1.2 0.3 1.0 2.2
Supplements: Fish oil (including cod liver oil) 0.4 0.5 2.6 -0.7 -1.1 -1.6 -0.8 -0.1 -0.2 0.2 0.6 -0.4 -1.0 -0.1 0.3 -0.7 -0.5 -0.7 0.2
High cholesterol (Self-reported) 0.5 0.9 3.9 2.0 -0.1 1.4 0.7 0.8 0.8 1.3 0.9 0.1 0.8 1.1 0.1 -0.3 0.4 0.9 0.9
Medication: Bendroflumethiazide 0.4 0.6 1.8 1.0 0.5 0.9 -0.3 -1.1 0.1 -1.3 -0.0 -1.3 -0.2 -1.2 -0.0 0.3 0.2 0.8 0.1
Medication: Paracetamol 0.4 0.7 2.2 1.5 0.1 1.2 -0.4 0.8 0.2 1.3 -0.7 0.4 -0.6 1.3 -0.4 -1.1 -0.2 0.5 0.2
Medication: Lisinopril 0.5 0.6 2.7 0.5 -0.0 0.5 0.7 -0.1 1.2 1.1 0.8 -0.0 0.7 0.1 0.8 0.1 0.8 1.6 1.2
Medication: Atorvastatin 0.6 0.7 5.3 1.8 -2.3 -0.4 -0.4 -0.1 -0.2 0.1 -0.5 -0.2 -0.5 0.2 -0.6 0.9 0.2 0.1 -0.6
Illnesses of father: High blood pressure 0.6 0.7 3.5 1.9 -1.8 0.5 -0.3 -0.7 -0.5 -0.4 1.1 -1.1 -0.1 -0.2 -0.4 0.2 0.0 0.6 -0.3
Alcohol drinker status: Never 0.4 0.4 1.1 1.0 -1.0 -0.8 -0.3 0.7 -0.3 0.4 -0.2 0.1 -0.2 0.7 -0.7 -0.6 -0.7 -1.1 -0.6
Ever smoked 1.3 2.3 6.5 0.3 1.3 1.7 1.9 -1.7 1.4 -0.7 -1.3 -0.5 2.0 -1.4 1.4 2.5 2.1 1.1 0.9
Basal metabolic rate 0.4 2.1 6.6 2.6 1.2 1.2 0.2 1.7 0.1 1.2 -2.2 1.9 0.1 2.1 -1.3 -0.4 0.3 -2.0 -1.2
Leg fat percentage (left) 0.9 3.4 8.5 0.6 2.7 1.5 0.2 2.7 2.1 0.8 2.9 1.0 0.5 2.1 -1.0 -2.7 -1.3 1.2 2.4
Arm fat-free mass (left) 0.6 3.2 11.1 2.0 1.3 1.5 0.1 2.9 0.3 2.2 -1.1 2.9 0.1 3.3 -1.7 -1.4 -0.7 -1.7 -0.6
Number of operations (self-reported) 0.5 0.7 2.5 0.6 -0.7 -1.4 -0.3 1.1 0.5 0.4 0.3 1.6 -0.1 1.4 -0.3 -1.2 -0.8 0.5 0.5
Average weekly beer plus cider intake 0.6 0.8 2.9 -1.2 -0.7 -0.9 -0.7 0.9 0.0 1.7 -0.4 1.0 -0.7 1.3 -1.0 -0.4 -1.1 -0.6 -0.1
Irritability 0.7 1.2 4.2 -0.1 2.1 0.4 0.7 -1.3 0.7 -0.4 -0.6 -0.7 0.9 -1.4 1.9 1.3 1.0 0.7 0.9
Risk taking 0.8 1.2 4.1 -0.4 0.5 -0.5 0.4 0.7 1.4 1.3 1.9 0.8 0.7 0.4 0.9 -0.7 -0.5 2.0 2.0
Ever had prostate specific antigen (PSA) test 0.5 0.6 2.2 -0.1 -1.2 0.1 0.5 0.6 0.6 0.9 1.3 1.5 0.6 0.8 0.1 0.4 0.0 0.6 0.8
Fractured/broken bones in last 5 years 0.9 1.2 4.1 -0.0 1.1 0.2 2.0 -0.7 1.6 -0.4 -0.9 -0.8 2.0 -0.7 1.1 0.9 1.0 -0.2 1.2
Age started oral contraceptive pill 1.6 1.9 4.3 -2.0 -1.3 0.1 -2.1 1.6 -0.7 0.8 0.2 0.8 -2.0 1.8 -1.8 -1.8 -1.6 -0.0 -0.7
Diastolic blood pressure, automated reading 0.8 2.6 7.1 1.7 1.9 0.6 1.2 1.7 1.2 1.8 2.7 1.4 1.1 2.1 -0.4 -2.5 -1.1 -0.1 1.7
Ever depressed for a whole week 1.7 2.1 14.1 1.4 0.3 1.7 0.8 -0.3 1.2 -1.2 0.3 0.6 1.1 -0.6 1.4 1.5 2.0 3.8 1.2
Unable to work because of sickness or disability 0.3 0.4 2.0 0.1 -0.0 1.4 0.1 -0.4 1.3 0.3 0.1 0.3 0.4 0.4 0.5 0.2 0.4 1.0 0.9
Commuting to job workplace: Cycle 0.7 0.8 4.6 -0.8 -0.9 -2.1 -1.1 -0.3 -0.8 -0.6 -0.6 0.2 -1.1 -0.4 -0.9 0.7 -0.6 0.4 -0.8
Myopia 2.6 3.8 8.4 -0.2 2.5 2.6 1.9 -2.6 1.5 -0.5 -0.9 -1.9 2.0 -2.1 2.4 1.9 2.9 1.7 1.3
Vascular/heart problems diagnosed by doctor 0.4 1.1 7.8 -2.8 1.4 -1.7 -0.1 0.6 -0.9 0.6 -1.0 0.9 -0.0 0.1 0.3 -0.0 -0.6 -1.0 -0.8
Cholesterol lowering medication 1.1 1.6 3.7 0.3 -1.4 -1.5 -1.4 -1.4 -1.0 -1.9 -1.1 -1.8 -1.3 -1.8 -0.3 0.4 -0.2 -1.0 -1.2
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 4.4 0.7 0.2 -0.9 0.9 -1.7 0.8 -1.4 -0.1 -1.7 0.7 -2.1 0.8 1.4 0.5 -0.0 0.9
Pain experienced in last month 0.4 0.7 4.6 -1.2 -0.3 -2.1 0.5 -0.6 -0.5 -0.9 -1.0 -0.3 0.3 -0.7 -0.0 1.0 0.0 -0.7 -0.7
Supplements: Calcium 3.0 3.3 7.2 -0.5 -2.7 -1.5 -2.0 -2.4 -1.9 -1.8 -1.6 -2.0 -2.0 -2.5 0.1 2.4 0.1 0.2 -1.8
Basal cell carcinoma (self-reported) 0.6 0.7 5.7 -1.4 -0.9 -2.4 0.3 -0.7 0.5 -0.5 -0.7 -0.4 0.3 -0.6 0.4 0.2 0.1 0.0 0.3
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.6 0.3 -0.2 0.7 -1.3 0.3 -0.8 0.0 -0.0 0.5 -1.2 0.1 -0.5 0.7 -0.3 0.3 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 1.4 -0.0 -0.2 0.5 -0.1 0.5 0.3 -0.1 0.5 0.9 -0.1 0.8 -1.1 -0.2 0.1 1.2 0.1
Heart disease (siblings) 0.6 0.8 6.4 2.5 -1.6 -0.8 0.1 -0.5 0.6 -0.1 -0.1 -1.1 0.3 0.1 0.2 0.3 0.4 0.4 0.5
Alcohol drinker status: Previous 1.0 1.1 7.6 2.8 0.6 2.1 -0.3 0.0 -0.5 0.7 0.8 0.7 -0.1 0.3 0.6 -0.2 0.8 1.7 -0.2
Pack years of smoking 0.7 1.0 3.6 -1.1 -0.8 1.9 -1.5 0.2 -0.8 0.2 0.4 0.1 -1.3 0.8 -1.5 -0.0 -1.0 0.8 -0.7
Impedance of whole body 2.1 10.8 32.6 -1.3 1.2 -0.1 2.0 -5.3 1.3 -4.5 -0.9 -4.4 1.9 -5.7 4.2 3.5 3.9 3.2 1.6
Leg fat mass (left) 0.8 3.0 8.3 1.4 2.9 1.8 0.4 2.9 1.9 1.1 1.8 1.6 0.7 2.5 -1.2 -2.2 -0.9 0.3 1.6
Arm predicted mass (left) 0.7 3.6 12.7 2.0 1.2 1.6 -0.3 3.1 0.1 2.4 -1.1 3.1 -0.3 3.6 -2.0 -1.6 -1.0 -1.8 -0.8