[Hub]/) : Traits : Pulse rate, automated reading :

chr16:29,905,882-31,860,399

Best TWAS P=4.39e-10 · Best GWAS P=4.71e-09 conditioned to 0.896

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RNF40 0.14 0.15 enet 7 0.15 1.9e-17 5.7 5.8 8.9e-09 0.69 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous STX4 0.06 0.05 lasso 2 0.02 7.8e-03 5.6 5.7 1.1e-08 0.75 0.03 0.88 FALSE
3 GTEx Adipose Subcutaneous RNF40 0.18 0.10 lasso 7 0.11 3.7e-09 5.8 5.6 1.8e-08 0.71 0.02 0.98 FALSE
4 GTEx Brain Caudate basal ganglia PRSS36 0.16 0.25 lasso 3 0.23 2.4e-07 5.0 5.1 2.9e-07 0.85 0.15 0.63 FALSE
5 GTEx Brain Cerebellum RNF40 0.24 0.16 lasso 5 0.13 9.7e-05 5.6 5.9 4.2e-09 0.78 0.02 0.94 FALSE
6 GTEx Cells Transformed fibroblasts RNF40 0.08 0.04 lasso 8 0.04 5.6e-04 5.7 6.2 4.4e-10 0.93 0.02 0.97 TRUE
7 GTEx Colon Transverse STX1B 0.12 0.01 lasso 5 0.00 3.9e-01 5.6 5.4 5.1e-08 0.84 0.05 0.33 FALSE
8 GTEx Esophagus Muscularis RNF40 0.16 0.10 lasso 1 0.08 1.3e-05 5.8 5.8 7.7e-09 0.70 0.01 0.97 FALSE
9 GTEx Nerve Tibial RNF40 0.13 0.08 lasso 5 0.09 8.1e-07 5.6 5.6 2.3e-08 0.67 0.02 0.98 FALSE
10 GTEx Ovary STX4 0.16 0.05 enet 13 0.07 9.0e-03 4.1 5.4 8.3e-08 0.86 0.06 0.52 FALSE
11 GTEx Skin Sun Exposed Lower leg STX4 0.04 0.02 enet 18 0.04 3.9e-04 3.2 5.2 2.5e-07 0.72 0.26 0.42 FALSE
12 GTEx Testis C16orf93 0.10 0.09 lasso 3 0.08 1.4e-04 5.8 -5.6 2.1e-08 -0.70 0.02 0.96 FALSE
13 GTEx Thyroid HSD3B7 0.27 0.12 lasso 4 0.17 7.0e-13 3.7 5.2 1.6e-07 0.81 0.06 0.94 FALSE
14 GTEx Thyroid RNF40 0.07 0.03 lasso 3 0.03 1.5e-03 5.6 5.9 2.9e-09 0.89 0.02 0.96 FALSE
15 GTEx Thyroid C16orf93 0.17 0.18 lasso 4 0.18 1.6e-13 5.7 -5.8 5.3e-09 -0.75 0.02 0.98 FALSE
16 METSIM Adipose RNF40 0.12 0.07 lasso 4 0.07 1.1e-10 5.6 5.7 9.5e-09 0.74 0.02 0.98 FALSE
17 ROSMAP Brain Pre-frontal Cortex RNF40 0.19 0.14 bslmm 201 0.15 2.7e-18 5.6 5.4 7.5e-08 0.54 0.02 0.98 FALSE
18 ROSMAP Brain Pre-frontal Cortex C16orf93 0.19 0.26 lasso 10 0.28 5.1e-36 5.6 -5.4 7.7e-08 -0.72 0.02 0.98 FALSE
19 YFS Blood ZNF785 0.05 0.07 lasso 4 0.06 2.0e-20 4.7 5.1 2.9e-07 0.66 0.74 0.26 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HSD3B7 0.06 0.01 blup 31 0.02 7.4e-04 4.4 5.2 2.0e-07 0.89 0.04 0.82 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C16orf93 0.02 0.02 blup 11 0.02 1.5e-03 5.8 -5.6 2.1e-08 -0.70 0.00 0.71 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RNF40 0.06 0.02 enet 4 0.03 6.0e-04 5.8 5.2 1.9e-07 0.62 0.00 0.86 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C16orf93 0.14 0.11 blup 10 0.11 4.5e-07 5.8 -5.5 3.8e-08 -0.70 0.00 1.00 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma C16orf93 0.09 0.09 blup 11 0.09 1.0e-10 5.6 -5.4 8.3e-08 -0.68 0.01 0.99 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma RNF40 0.09 0.08 blup 12 0.07 2.1e-08 5.8 5.3 9.6e-08 0.64 0.00 1.00 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma RNF40 0.07 0.11 lasso 5 0.10 7.5e-11 5.8 5.8 7.8e-09 0.71 0.00 1.00 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma C16orf93 0.15 0.19 lasso 4 0.19 1.8e-18 5.8 -5.8 8.5e-09 -0.71 0.00 1.00 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma RNF40 0.06 0.04 blup 12 0.06 3.6e-06 5.8 5.1 2.9e-07 0.58 0.00 0.99 FALSE