Hub : Genes

HSD3B7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0470	0.0190	3.5e-06	0.061	0.045	0.063	0.049	0.071	6.8e-08	3.0e-06	4.1e-08	1.1e-06	5.5e-09
2	GTEx	Adrenal Gland	0.2139	0.0779	1.2e-04	0.167	NA	0.088	NA	0.126	1.3e-06	NA	4.6e-04	NA	2.9e-05
3	GTEx	Artery Tibial	0.0761	0.0361	4.1e-03	0.007	NA	0.009	NA	0.009	8.0e-02	NA	6.2e-02	NA	5.7e-02
4	GTEx	Cells Transformed fibroblasts	0.1070	0.0450	8.3e-05	0.070	NA	0.051	NA	0.064	6.4e-06	NA	1.0e-04	NA	1.4e-05
5	GTEx	Colon Transverse	0.1560	0.0500	5.0e-08	0.147	NA	0.190	NA	0.170	1.8e-07	NA	2.1e-09	NA	1.6e-08
6	GTEx	Esophagus Mucosa	0.3770	0.0730	0.0e+00	0.316	NA	0.340	NA	0.355	1.2e-21	NA	2.0e-23	NA	1.2e-24
7	GTEx	Heart Left Ventricle	0.1157	0.0511	9.0e-05	0.079	NA	0.065	NA	0.067	5.4e-05	NA	2.3e-04	NA	2.0e-04
8	GTEx	Muscle Skeletal	0.1505	0.0476	5.5e-13	0.126	NA	0.144	NA	0.137	2.4e-12	NA	5.4e-14	NA	2.2e-13
9	GTEx	Nerve Tibial	0.0874	0.0384	1.5e-03	0.053	NA	0.027	NA	0.032	1.3e-04	NA	5.0e-03	NA	2.5e-03
10	GTEx	Pituitary	0.1280	0.0590	1.4e-03	0.072	NA	0.043	NA	0.051	7.3e-03	NA	3.1e-02	NA	2.1e-02
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1140	0.0600	2.1e-05	0.120	NA	0.097	NA	0.096	4.1e-07	NA	5.9e-06	NA	6.1e-06
12	GTEx	Skin Sun Exposed Lower leg	0.1200	0.0420	1.4e-11	0.166	NA	0.151	NA	0.161	1.2e-13	NA	1.6e-12	NA	2.7e-13
13	GTEx	Thyroid	0.2730	0.0750	1.7e-10	0.119	NA	0.103	NA	0.168	2.3e-09	NA	3.0e-08	NA	7.0e-13
14	GTEx	Whole Blood	0.0590	0.0260	4.5e-04	0.065	NA	0.061	NA	0.061	1.3e-06	NA	2.9e-06	NA	2.6e-06
15	METSIM	Adipose	0.0517	0.0253	1.8e-03	0.018	0.020	0.001	0.022	0.009	9.6e-04	4.5e-04	2.0e-01	2.1e-04	1.6e-02
16	ROSMAP	Brain Pre-frontal Cortex	0.0338	0.0161	4.3e-05	0.047	0.021	0.023	0.019	0.025	9.7e-07	9.5e-04	5.8e-04	1.6e-03	3.0e-04
17	YFS	Blood	0.0559	0.0191	8.5e-09	0.022	0.029	0.017	0.028	0.019	9.9e-08	8.9e-10	2.2e-06	1.5e-09	4.4e-07
18	TCGA	Bladder Urothelial Carcinoma	0.0350	0.0290	6.2e-03	0.020	0.014	0.027	NA	0.020	7.3e-03	2.2e-02	2.1e-03	NA	7.3e-03
19	TCGA	Breast Invasive Carcinoma	0.0276	0.0162	2.7e-08	0.032	0.036	0.025	NA	0.030	3.6e-07	5.2e-08	5.5e-06	NA	7.1e-07
20	TCGA	Head and Neck Squamous Cell Carcinoma	0.0592	0.0483	2.9e-04	0.013	0.025	0.017	NA	0.019	1.0e-02	7.4e-04	5.0e-03	NA	3.2e-03
21	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1410	0.0680	6.1e-09	0.140	0.147	0.147	NA	0.150	2.0e-08	8.6e-09	8.8e-09	NA	6.1e-09
22	TCGA	Liver Hepatocellular Carcinoma	0.0840	0.0540	2.4e-04	0.051	0.052	0.033	NA	0.049	2.0e-03	1.8e-03	1.1e-02	NA	2.4e-03
23	TCGA	Ovarian Serous Cystadenocarcinoma	0.0410	0.0300	1.2e-03	0.045	0.048	0.040	NA	0.041	5.4e-04	3.6e-04	1.0e-03	NA	8.9e-04
24	TCGA	Pheochromocytoma and Paraganglioma	0.0900	0.0600	2.1e-04	0.116	0.110	0.069	NA	0.109	2.5e-05	4.1e-05	1.0e-03	NA	4.2e-05
25	TCGA	Prostate Adenocarcinoma	0.2413	0.1137	0.0e+00	0.266	0.254	0.259	NA	0.263	9.9e-28	2.0e-26	5.1e-27	NA	2.0e-27
26	TCGA	Thyroid Carcinoma	0.1970	0.0850	0.0e+00	0.274	0.275	0.276	NA	0.281	9.5e-27	7.1e-27	6.5e-27	NA	1.8e-27

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Forced expiratory volume in 1-second (FEV1), predicted percentage	15.9	33.7	45.0	-6.4	-5.4	-1.0	-4.9	-5.8	-6.3	-6.3	-6.5	-6.0	-6.2	-6.3	-6.2	-5.7	5.9	-1.5	-6.3	3.7	-6.0	-6.5	-6.2	-5.6	-6.0	-6.7	-6.7	-6.1	-6.2
Irritability	15.4	26.1	39.3	-5.3	-4.6	-2.7	-4.5	-5.6	-5.1	-5.9	-4.6	-5.1	-6.1	-5.2	-5.9	-4.6	3.0	-3.4	-4.8	-0.9	-6.3	-5.6	-4.7	-5.4	-5.9	-5.5	-6.0	-6.0	-6.1
Tense / ‘highly strung’	13.1	21.7	29.4	-5.4	-4.3	-1.8	-4.4	-4.9	-4.8	-5.2	-4.2	-5.2	-5.2	-4.9	-5.1	-4.1	4.3	-1.2	-5.1	1.5	-5.1	-5.2	-4.7	-4.7	-5.0	-5.3	-5.4	-5.1	-5.2
Neuroticism (Nagel 2018)	13.0	30.5	41.0	-6.3	-5.6	-3.3	-5.4	-5.4	-5.8	-6.1	-5.1	-6.1	-6.4	-5.9	-6.2	-4.2	4.1	-3.2	-6.1	0.2	-6.2	-6.1	-5.2	-5.4	-6.1	-6.0	-6.3	-5.9	-6.4
Hip circumference	12.4	53.5	118.8	7.5	6.1	-3.0	5.1	7.0	7.5	7.2	8.2	6.3	7.1	7.6	7.0	7.6	-10.9	-0.5	7.9	-8.8	6.1	8.3	9.3	6.4	6.8	9.2	8.3	6.7	7.1
Blood Red Count	12.2	117.9	151.3	-11.0	-10.9	-6.7	-10.5	-11.8	-11.5	-12.0	-12.1	-11.2	-12.3	-11.9	-11.9	-10.3	6.1	-6.5	-11.5	1.9	-11.7	-11.7	-10.4	-11.3	-12.2	-11.4	-12.0	-12.0	-12.3
Alzheimer’s Disease (including proxy)	12.1	17.6	33.8	-4.3	-3.3	0.7	-3.4	-4.0	-4.1	-4.2	-4.6	-3.7	-4.3	-4.3	-4.2	-4.6	5.2	0.6	-4.3	4.0	-3.0	-5.0	-5.8	-4.5	-4.2	-5.2	-4.6	-4.1	-4.4
Waist circumference	11.5	41.9	96.2	6.6	5.2	-2.8	4.6	6.0	6.7	6.3	6.7	5.6	6.2	6.6	6.1	7.0	-9.8	-0.8	7.0	-8.1	4.8	7.5	8.7	5.9	6.0	8.2	7.1	5.8	6.2
Worry (Nagel 2018)	11.3	23.8	33.1	-5.6	-4.6	-1.9	-4.9	-4.4	-5.1	-5.3	-4.4	-5.3	-5.5	-5.1	-5.2	-4.0	4.7	-1.0	-5.7	2.2	-4.9	-5.7	-5.5	-4.8	-5.3	-5.8	-5.7	-5.1	-5.5
Neuroticism score	10.9	22.8	31.6	-5.4	-4.9	-3.3	-4.7	-5.0	-4.9	-5.4	-4.6	-5.5	-5.4	-5.0	-5.3	-3.9	3.2	-2.8	-5.2	-1.1	-5.6	-5.1	-4.0	-4.7	-5.1	-5.0	-5.5	-5.2	-5.3
Neuroticism	10.8	26.1	35.7	-5.8	-5.3	-2.8	-5.0	-5.2	-5.4	-5.7	-4.9	-5.9	-5.8	-5.4	-5.7	-4.2	4.1	-2.5	-5.7	-0.4	-6.0	-5.5	-4.5	-4.9	-5.4	-5.6	-5.9	-5.5	-5.7
Worrier / anxious feelings	10.7	20.2	29.1	-5.1	-4.8	-3.3	-5.0	-4.2	-4.8	-4.9	-4.2	-5.1	-4.9	-4.9	-4.8	-4.2	3.1	-2.5	-5.4	0.7	-4.3	-5.0	-4.4	-4.6	-4.8	-4.9	-4.8	-4.6	-4.9
Forced expiratory volume in 1-second (FEV1), Best measure	10.6	33.8	48.8	-6.2	-5.4	-1.2	-4.3	-6.0	-6.1	-6.7	-6.4	-6.0	-6.5	-6.2	-6.6	-5.2	5.7	-1.9	-6.3	2.4	-7.0	-6.3	-5.4	-5.8	-6.2	-6.5	-6.9	-6.6	-6.5
Leg fat mass (left)	9.9	38.5	85.7	6.1	4.9	-2.7	4.2	5.8	6.3	6.1	6.8	5.2	6.0	6.4	6.0	6.5	-9.3	-1.1	6.8	-7.6	5.1	7.1	8.0	5.7	5.8	7.8	7.0	5.8	6.0
High blood pressure (siblings)	9.7	14.0	29.8	3.9	3.4	-1.2	2.4	3.8	3.9	3.8	4.0	3.4	3.8	3.9	3.7	3.6	-5.5	0.4	4.2	-4.6	3.4	4.0	4.5	3.3	3.5	4.5	4.1	3.6	3.8
Triglycerides	9.6	15.6	26.7	3.8	3.1	-1.3	2.4	3.4	3.9	4.3	4.4	3.3	4.2	4.0	4.2	3.9	-5.2	-0.4	4.0	-3.5	3.7	4.7	5.0	4.2	4.1	4.9	4.8	4.2	4.3
Cholesterol lowering medication	9.6	14.1	19.6	4.3	3.5	0.4	2.9	4.1	4.0	4.1	3.9	3.9	4.0	4.1	3.9	3.9	-4.2	1.6	4.0	-2.5	4.1	4.1	3.9	3.4	3.8	4.4	4.4	3.8	4.0
Leg fat mass (right)	9.5	36.9	83.5	6.1	4.8	-2.6	4.1	5.6	6.2	5.9	6.6	5.2	5.8	6.2	5.8	6.4	-9.1	-1.2	6.7	-7.6	4.9	6.9	7.8	5.5	5.6	7.6	6.8	5.6	5.9
Arm fat mass (left)	9.4	38.5	95.5	6.2	4.7	-3.3	4.1	5.6	6.2	5.9	6.7	5.0	5.8	6.2	5.7	6.7	-9.8	-1.5	6.7	-8.2	4.6	7.2	8.4	5.5	5.6	7.9	6.9	5.5	5.9
Leg fat percentage (left)	9.3	33.6	68.7	6.0	4.8	-1.9	4.1	5.5	5.9	5.9	6.2	5.2	5.7	6.0	5.7	6.0	-8.3	-0.6	6.4	-6.4	5.0	6.6	7.2	5.4	5.5	7.2	6.6	5.5	5.7
Lung FVC	9.2	47.1	62.9	-7.6	-7.0	-2.9	-6.3	-7.0	-7.3	-7.8	-7.1	-7.5	-7.5	-7.5	-7.6	-5.6	5.6	-3.0	-7.9	2.7	-7.7	-7.4	-6.4	-6.9	-7.4	-7.5	-7.9	-7.5	-7.5
Body fat percentage	9.2	36.5	72.8	6.6	5.3	-1.5	4.8	5.8	6.2	6.1	6.2	5.7	5.8	6.2	5.8	6.5	-8.5	-0.5	7.0	-6.6	4.9	6.9	7.5	5.5	5.6	7.5	6.7	5.6	5.8
Arm fat percentage (left)	9.0	35.7	79.9	6.2	4.8	-2.5	4.3	5.6	6.0	5.8	6.4	5.2	5.7	6.1	5.6	6.6	-8.9	-1.0	6.7	-7.4	4.5	6.9	7.9	5.4	5.5	7.5	6.6	5.4	5.7
Arm fat percentage (right)	8.9	35.3	80.8	6.1	4.8	-2.5	4.1	5.5	5.9	5.8	6.4	5.1	5.7	6.0	5.6	6.5	-9.0	-1.1	6.5	-7.3	4.6	6.8	7.8	5.3	5.5	7.5	6.7	5.4	5.7
Forced expiratory volume in 1-second (FEV1)	8.9	30.2	44.3	-6.2	-5.5	-2.3	-4.6	-5.6	-5.9	-6.3	-6.0	-6.0	-6.2	-5.9	-6.1	-4.7	4.6	-2.4	-6.1	1.5	-6.7	-5.8	-4.7	-5.3	-5.9	-5.9	-6.4	-6.1	-6.1
Arm fat mass (right)	8.9	36.8	95.5	6.0	4.4	-3.5	3.8	5.5	6.0	5.7	6.6	4.8	5.7	6.0	5.6	6.4	-9.8	-1.7	6.5	-8.3	4.4	7.0	8.3	5.4	5.4	7.8	6.7	5.4	5.7
Leg fat percentage (right)	8.8	32.0	63.7	6.0	4.8	-1.5	4.1	5.4	5.8	5.8	6.0	5.3	5.6	5.8	5.6	5.8	-8.0	-0.5	6.3	-6.1	5.1	6.4	6.8	5.2	5.4	7.0	6.5	5.4	5.6
Whole body fat mass	8.8	36.6	84.1	6.2	4.8	-2.6	4.3	5.6	6.2	5.9	6.4	5.2	5.7	6.1	5.7	6.5	-9.2	-1.2	6.7	-7.6	4.6	6.9	8.0	5.5	5.5	7.6	6.7	5.5	5.8
Body mass index (BMI)	8.7	37.1	107.7	5.7	4.2	-4.4	3.0	5.4	5.9	5.7	7.0	4.5	5.6	6.0	5.6	6.3	-10.4	-2.2	6.2	-8.8	4.9	6.8	8.0	5.1	5.3	7.7	6.8	5.4	5.7
Nervous feelings	8.6	16.0	25.0	-4.5	-3.5	-0.7	-3.8	-3.7	-4.2	-4.1	-3.5	-4.1	-4.2	-4.1	-4.1	-4.0	4.6	0.3	-4.8	2.6	-3.4	-4.8	-5.0	-4.1	-4.2	-4.9	-4.6	-3.9	-4.2
Illnesses of siblings	8.6	12.1	26.6	-3.4	-2.8	1.4	-1.8	-3.5	-3.7	-3.6	-4.0	-2.9	-3.5	-3.6	-3.5	-3.5	5.2	-0.6	-3.5	4.5	-3.4	-3.7	-4.0	-3.1	-3.3	-4.2	-3.8	-3.5	-3.5
Comparative body size at age 10	8.5	23.5	38.4	5.0	4.8	1.3	4.5	5.2	5.3	5.0	6.2	5.0	4.7	5.6	4.9	6.2	-4.2	1.0	5.5	-2.6	4.2	5.5	5.3	4.8	4.9	5.5	5.4	4.7	4.8
Pain experienced in last month	8.5	14.2	21.7	-4.3	-4.0	-0.4	-3.3	-4.0	-4.1	-4.0	-4.7	-4.0	-3.9	-4.3	-3.8	-4.2	3.9	-0.9	-4.2	2.3	-3.7	-4.1	-4.1	-3.2	-3.7	-4.3	-4.2	-3.6	-3.9
Wheeze or whistling in the chest in last year	8.4	14.9	24.6	3.6	3.4	-0.0	3.1	3.6	3.8	4.3	5.0	3.7	4.3	4.1	4.1	3.8	-3.8	0.3	3.8	-1.9	3.8	4.5	4.6	4.1	4.2	4.6	4.6	4.2	4.3
Trunk fat percentage	8.3	33.1	63.5	6.4	5.2	-1.1	4.8	5.6	6.0	5.8	5.8	5.5	5.5	5.9	5.5	6.3	-8.0	-0.3	6.8	-6.1	4.5	6.5	7.2	5.3	5.3	7.1	6.3	5.2	5.5
Trunk fat mass	8.2	35.4	75.9	6.3	5.0	-2.1	4.6	5.6	6.1	5.8	6.1	5.3	5.6	6.1	5.6	6.4	-8.7	-0.9	6.8	-7.1	4.4	6.9	7.9	5.4	5.5	7.5	6.5	5.3	5.7
Number of incorrect matches in round	7.9	13.1	33.2	-3.7	-3.0	2.1	-1.9	-3.6	-3.6	-3.6	-4.0	-3.2	-3.4	-3.7	-3.5	-3.7	5.8	1.4	-3.9	4.2	-3.1	-3.9	-4.4	-3.3	-3.2	-4.5	-4.0	-3.5	-3.4
High cholesterol (Self-reported)	7.8	13.8	18.8	4.1	3.4	0.8	2.6	3.8	4.1	4.2	4.2	3.7	4.0	3.9	4.2	4.0	-3.8	0.8	3.7	-1.2	4.2	4.0	3.6	4.0	3.9	4.2	4.3	4.3	4.0
Weight	7.7	37.9	95.1	5.9	4.5	-3.6	4.0	5.5	6.1	5.7	6.6	4.7	5.8	6.2	5.7	6.6	-9.8	-1.6	6.5	-8.5	4.3	7.2	8.6	5.5	5.6	7.9	6.8	5.4	5.8
Forced vital capacity (FVC), Best measure	7.6	27.9	49.1	-5.7	-5.0	-1.3	-3.7	-5.6	-5.5	-6.2	-6.0	-5.6	-5.9	-5.6	-6.1	-4.1	5.2	-1.9	-5.7	1.9	-7.0	-5.4	-4.2	-5.2	-5.6	-5.7	-6.4	-6.1	-5.8
Cardiovascular Disease	7.4	24.6	46.6	5.1	4.7	-1.4	3.6	4.7	5.2	5.1	5.6	4.8	4.5	5.2	4.9	5.5	-6.8	-0.2	5.5	-5.6	3.9	5.6	6.1	4.9	4.6	6.1	5.5	4.8	4.5
Medication: Cholesterol lowering	7.4	11.5	16.1	3.6	3.4	0.2	2.4	3.4	3.6	3.9	3.5	3.4	3.6	3.5	3.8	3.0	-4.0	1.1	3.5	-1.9	3.9	3.6	3.4	3.5	3.5	3.9	4.0	3.8	3.6
Forced vital capacity (FVC)	7.3	27.9	48.3	-6.0	-5.5	-2.2	-4.1	-5.4	-5.8	-6.2	-5.9	-5.9	-5.9	-5.7	-6.0	-4.0	4.6	-2.4	-5.8	1.3	-6.9	-5.3	-4.0	-4.9	-5.5	-5.6	-6.2	-6.0	-5.8
BMI	7.2	41.8	116.6	6.0	4.5	-4.4	3.4	5.7	6.2	6.0	7.2	5.0	6.0	6.5	5.9	6.3	-10.8	-2.3	6.7	-9.3	5.1	7.3	8.6	5.6	5.7	8.2	7.3	5.8	6.1
Overall health rating	7.2	15.4	39.2	3.4	2.9	-2.6	1.8	3.7	3.9	3.9	4.2	3.0	4.1	3.7	4.0	4.0	-6.3	-1.2	3.4	-4.4	3.8	4.4	5.2	3.6	3.8	5.0	4.6	4.0	4.1
Depressed Affect (Nagel 2018)	7.0	14.7	23.7	-4.9	-4.1	-3.7	-4.1	-3.9	-3.8	-4.3	-3.6	-4.6	-4.3	-4.1	-4.2	-2.6	1.9	-2.9	-4.1	-1.9	-4.5	-3.9	-2.9	-3.5	-4.1	-3.8	-4.2	-4.0	-4.3
Diastolic blood pressure, automated reading	6.9	21.5	49.2	4.0	3.6	-1.3	3.5	4.1	4.5	4.5	4.2	3.6	4.8	4.8	4.6	5.4	-5.8	0.9	4.4	-5.7	2.9	5.7	7.0	5.1	4.9	5.9	5.1	4.5	4.9
Fractured/broken bones in last 5 years	6.8	8.8	12.0	2.8	2.6	-0.2	2.0	3.4	3.3	3.0	2.6	2.5	3.5	3.2	3.2	2.4	-3.3	2.8	2.7	-3.2	3.3	3.1	3.2	2.7	3.0	3.4	3.2	3.2	3.4
Asthma	6.6	13.1	18.1	3.3	3.4	2.5	3.7	4.0	3.5	4.0	4.1	3.7	4.2	3.7	4.0	4.1	-1.1	2.1	3.2	1.1	3.7	4.0	3.6	4.1	4.3	3.7	4.0	4.1	4.2
Mood swings	6.6	11.9	16.7	-3.9	-3.5	-3.2	-3.6	-3.8	-3.4	-3.8	-3.2	-4.0	-4.0	-3.6	-3.8	-2.7	1.3	-2.7	-3.4	-1.9	-4.1	-3.6	-2.7	-3.4	-3.9	-3.4	-3.8	-3.7	-4.0
Chronic bronchitis/emphysema (mother)	6.5	7.6	11.2	2.9	3.0	1.8	2.8	3.0	2.8	3.0	3.2	3.3	3.1	3.0	2.9	2.6	-1.5	1.0	2.9	-0.1	3.0	2.9	2.5	2.6	3.0	2.8	3.0	2.9	3.1
Knee pain experienced in last month	6.5	10.1	18.2	3.5	3.1	-0.6	2.5	2.9	3.1	3.4	4.2	3.2	3.0	3.6	3.0	2.7	-4.3	0.6	3.5	-3.5	3.0	3.5	3.5	2.5	2.9	3.8	3.7	2.8	3.0
Medication for cholesterol	6.5	9.8	16.3	-3.9	-3.2	-0.2	-3.0	-3.1	-3.5	-3.2	-3.3	-3.8	-2.9	-3.4	-2.9	-3.5	3.9	-0.3	-4.0	2.6	-2.7	-3.3	-3.4	-2.3	-2.7	-3.7	-3.4	-2.7	-2.9
Chronic bronchitis/emphysema (father)	6.4	7.5	11.2	3.1	2.9	1.1	2.7	3.0	3.1	3.0	3.4	3.1	3.0	2.9	2.9	2.4	-2.1	1.4	2.9	-0.4	2.9	2.9	2.6	2.6	2.9	3.0	3.0	2.9	2.9
Number of treatments/medications taken	6.3	11.3	15.7	3.8	3.3	1.5	3.3	3.5	3.6	3.6	3.6	3.5	3.4	3.6	3.4	4.0	-2.9	1.6	3.7	-1.7	2.9	3.8	3.8	3.4	3.5	3.8	3.7	3.3	3.4
Number of full sisters	6.2	7.6	13.0	3.2	2.9	0.7	2.8	2.6	2.9	3.0	3.6	3.1	2.8	2.9	2.8	2.1	-2.5	0.6	3.5	-1.8	2.4	3.0	3.1	2.7	2.8	3.1	2.9	2.7	2.8
Medication: Atorvastatin	6.2	7.6	13.5	3.1	2.5	0.5	2.0	3.6	2.8	3.1	2.5	2.7	2.9	2.8	3.0	3.7	-2.8	1.4	2.5	-1.6	2.9	2.9	2.8	2.8	2.8	3.0	3.1	3.0	2.9
Frequency of tenseness / restlessness in last 2 weeks	6.1	9.5	13.5	-3.1	-2.6	-2.4	-3.2	-3.3	-3.0	-3.4	-2.3	-3.1	-3.5	-3.4	-3.4	-3.2	1.4	-2.4	-3.2	0.3	-3.0	-3.5	-3.2	-3.7	-3.7	-3.3	-3.4	-3.4	-3.5
Alzheimer’s Disease (in mother)	6.0	7.1	16.9	-2.8	-2.0	1.3	-1.9	-2.4	-2.6	-2.5	-2.9	-2.2	-2.4	-2.7	-2.4	-3.2	4.1	1.1	-3.0	3.1	-1.5	-3.1	-3.9	-2.5	-2.3	-3.4	-2.7	-2.3	-2.4
Asthma (self-reported)	6.0	12.0	16.7	3.1	3.2	2.4	3.5	3.9	3.2	3.8	3.9	3.5	4.0	3.6	3.8	4.0	-0.9	2.2	3.0	1.2	3.5	3.9	3.5	4.0	4.1	3.5	3.8	4.0	4.0
Suffer from ‘nerves’	5.8	9.0	16.8	-2.8	-2.5	-1.1	-3.1	-2.6	-3.0	-3.2	-2.6	-3.0	-3.4	-3.2	-3.2	-3.1	2.6	-1.1	-3.1	1.0	-2.2	-3.8	-4.1	-3.6	-3.5	-3.7	-3.4	-3.1	-3.4
Relative age voice broke	5.7	8.8	12.9	3.0	3.6	2.4	3.3	3.2	3.4	3.1	1.8	3.3	3.2	3.2	3.1	2.8	-1.3	2.9	3.6	-0.9	3.2	3.0	2.5	2.8	3.2	2.9	3.1	3.1	3.2
Hypertension (Self-reported)	5.7	15.8	31.7	3.8	3.3	-1.5	2.8	3.6	3.9	3.9	4.4	3.4	3.8	4.1	3.8	4.5	-5.6	-0.5	4.3	-5.1	2.7	4.6	5.5	3.8	3.8	5.0	4.3	3.6	3.8
Vascular/heart problems diagnosed by doctor	5.6	15.2	36.0	-3.6	-3.0	2.1	-2.2	-3.5	-3.8	-3.8	-4.2	-3.0	-3.6	-3.9	-3.7	-4.3	6.0	0.9	-4.0	5.7	-2.8	-4.5	-5.3	-3.7	-3.6	-4.9	-4.3	-3.6	-3.6
Hearing difficulty/problems: Yes	5.5	8.5	17.6	2.5	2.8	1.1	1.9	3.4	3.0	3.4	3.2	2.7	3.7	3.1	3.5	2.4	-1.8	1.4	2.8	-0.3	4.2	2.9	2.2	3.0	3.4	2.9	3.5	3.6	3.6
High blood pressure	5.3	14.8	33.1	3.5	3.0	-1.9	2.4	3.5	3.8	3.7	4.2	3.0	3.5	3.9	3.6	4.4	-5.8	-0.9	4.0	-5.4	2.5	4.5	5.4	3.7	3.6	4.9	4.2	3.5	3.6
Pain all over the body in last month	5.0	5.4	8.8	2.5	2.2	0.8	1.9	2.5	2.8	2.4	3.0	2.3	2.4	2.6	2.5	2.9	-2.1	-0.0	2.4	-0.7	2.3	2.5	2.4	2.2	2.4	2.5	2.5	2.4	2.4
Medication: Simvastatin	5.0	7.4	10.9	2.8	2.5	0.1	1.8	2.6	2.8	3.0	2.9	2.7	3.0	2.8	2.9	2.3	-3.3	0.7	2.9	-2.1	3.2	3.0	2.8	2.6	2.8	3.2	3.3	2.9	3.0
Pulse rate, automated reading	5.0	16.1	27.4	3.5	3.8	2.1	4.3	4.4	4.3	4.1	3.9	3.7	4.4	4.4	4.2	5.2	-1.9	2.8	3.8	-0.5	2.7	4.7	5.2	4.9	4.7	4.4	3.9	4.2	4.5
Neuroticism (2016)	4.9	7.1	10.5	-3.2	-2.9	-1.4	-2.5	-2.9	-3.0	-3.0	-2.5	-2.7	-2.9	-3.0	-3.1	-2.5	1.8	-1.2	-3.2	-0.5	-3.0	-2.8	-2.5	-2.5	-2.8	-2.8	-2.9	-2.7	-2.9
Respiratory disease	4.9	10.9	16.0	2.7	2.6	0.9	2.7	3.4	3.1	3.6	3.9	3.1	3.9	3.4	3.7	3.7	-2.1	0.9	3.0	0.4	3.3	4.0	4.0	4.0	4.0	3.8	3.9	3.9	3.9
Townsend deprivation index at recruitment	4.9	6.9	15.6	3.1	2.6	-0.7	1.9	2.7	2.7	2.5	3.6	2.9	2.4	2.7	2.3	2.9	-4.0	-1.0	2.7	-3.1	2.2	2.7	3.0	1.9	2.2	3.1	2.8	2.2	2.4
Number of self-reported non-cancer illnesses	4.8	8.3	11.4	3.2	2.9	0.8	2.5	2.8	3.1	3.1	3.1	2.9	2.9	3.0	3.0	3.4	-2.8	1.3	3.1	-2.1	2.6	3.2	3.3	2.9	2.9	3.3	3.2	2.9	2.9
Myopia	4.8	7.0	9.9	3.1	2.9	1.2	2.6	2.8	3.0	3.0	2.8	3.1	2.5	2.8	2.9	2.7	-2.2	1.6	2.6	-0.4	2.4	2.8	2.6	3.0	2.6	2.9	2.8	3.0	2.5
Medication: Bendroflumethiazide	4.5	6.9	24.0	2.5	1.4	-1.3	1.9	2.3	2.2	2.4	2.5	1.8	2.2	2.5	2.2	3.1	-3.9	0.2	2.7	-4.9	1.1	3.1	4.1	2.6	2.3	3.4	2.7	2.1	2.3
Hand grip strength (left)	4.4	11.6	17.2	3.3	3.0	-0.4	2.6	3.3	3.2	3.6	3.9	3.0	3.7	3.7	3.5	3.8	-3.7	1.0	3.4	-2.9	3.3	4.1	4.1	3.4	3.6	4.2	4.1	3.4	3.7
Alcohol intake frequency.	4.3	10.1	30.1	2.3	1.2	-3.3	1.1	2.8	2.9	2.7	2.8	1.8	3.0	2.9	2.8	3.8	-5.5	-1.5	2.6	-4.8	1.9	3.8	5.1	3.0	2.9	4.2	3.5	2.8	3.1
Alzheimer’s Disease (in father)	4.2	4.6	7.7	-2.2	-1.8	0.1	-1.9	-2.2	-2.1	-2.2	-2.2	-2.1	-2.2	-2.2	-2.1	-2.3	2.4	0.4	-2.2	2.4	-1.6	-2.5	-2.8	-2.3	-2.2	-2.5	-2.3	-2.1	-2.2
Loneliness, isolation	4.1	5.7	13.2	-2.6	-2.8	-3.6	-2.9	-2.5	-2.0	-2.4	-2.4	-2.9	-2.4	-2.5	-2.3	-1.8	-0.4	-2.8	-2.6	-2.6	-2.5	-2.0	-1.0	-2.0	-2.4	-1.7	-2.2	-2.1	-2.4
Financial difficulties in last 2 years	4.0	5.3	18.6	2.5	1.8	-2.0	1.6	1.7	2.5	1.9	2.4	2.4	1.5	2.0	1.9	2.7	-4.3	-1.5	2.3	-3.7	1.2	2.4	3.2	1.8	1.6	2.9	2.2	1.8	1.6
Birth weight of first child	4.0	7.3	12.4	3.3	3.3	1.7	3.3	3.1	3.3	2.7	2.8	3.3	2.4	3.2	2.6	3.1	-1.9	1.7	3.5	-0.4	1.9	2.8	2.7	2.5	2.5	2.8	2.5	2.3	2.4
Arm predicted mass (left)	4.0	20.2	61.8	3.7	2.7	-4.0	2.0	3.7	4.3	3.8	4.8	2.7	4.3	4.3	4.0	4.3	-7.9	-2.0	4.2	-7.3	3.2	5.2	6.5	3.7	3.9	5.8	5.0	3.9	4.3
Falls in the last year	3.9	5.3	12.4	2.6	2.1	-0.9	1.7	2.2	2.2	2.1	2.8	2.3	2.2	2.5	2.0	2.5	-3.5	-0.7	3.0	-2.3	1.9	2.4	2.7	1.6	2.0	2.8	2.5	1.8	2.2
Medication: Blood pressure	3.9	7.3	16.1	2.9	2.3	-0.8	2.4	2.4	2.8	2.6	2.8	2.6	2.4	2.6	2.4	3.3	-4.0	-0.6	3.1	-3.6	1.6	3.1	3.8	2.2	2.4	3.4	2.9	2.1	2.5
Sensitivity / hurt feelings	3.8	6.4	9.2	-2.6	-2.6	-1.1	-2.2	-2.6	-2.8	-2.8	-2.5	-2.9	-2.8	-2.7	-2.9	-2.2	2.1	-1.8	-2.6	-0.5	-3.0	-2.7	-2.2	-2.6	-2.7	-2.7	-2.9	-2.8	-2.8
Fed-up feelings	3.8	6.9	13.8	-3.0	-2.7	-2.6	-2.5	-2.6	-2.4	-3.0	-2.2	-3.1	-3.1	-2.6	-2.9	-1.4	1.0	-3.1	-2.6	-1.9	-3.7	-2.4	-1.3	-2.2	-2.8	-2.3	-2.9	-2.9	-3.0
Arm fat-free mass (left)	3.6	18.3	59.8	3.5	2.5	-4.2	1.8	3.4	4.0	3.5	4.4	2.4	3.9	4.0	3.6	4.1	-7.7	-2.0	4.0	-7.5	2.8	4.9	6.3	3.4	3.5	5.5	4.6	3.5	3.9
Unable to work because of sickness or disability	3.6	4.7	15.8	2.1	1.6	-2.2	0.8	2.0	2.2	1.8	2.5	1.6	1.8	2.1	1.8	2.3	-4.0	-1.2	2.2	-3.2	1.5	2.3	2.9	1.6	1.7	2.7	2.3	1.7	1.8
Diverticular disease/diverticulitis (self-reported)	3.5	4.2	9.4	-2.1	-2.2	-1.9	-1.5	-2.5	-1.9	-2.3	-1.7	-2.2	-2.5	-2.0	-2.3	-1.5	0.4	-1.9	-1.7	-2.0	-3.1	-1.8	-1.0	-1.7	-2.3	-1.7	-2.3	-2.3	-2.5
Breastfed as a baby	3.5	4.4	9.0	2.8	2.5	2.6	3.0	2.4	2.3	2.1	1.8	2.6	1.8	2.2	1.9	2.7	-0.5	1.8	2.5	-0.5	1.3	2.1	1.9	1.9	1.9	1.9	1.7	1.7	1.8
Arm predicted mass (right)	3.5	18.1	53.3	3.4	2.5	-3.7	2.0	3.5	4.1	3.6	4.5	2.5	3.9	4.1	3.8	4.3	-7.3	-1.8	4.0	-7.2	2.8	4.9	6.2	3.7	3.7	5.4	4.6	3.7	4.0
Miserableness	3.5	6.1	8.5	-2.6	-2.2	-2.1	-2.4	-2.9	-2.3	-2.7	-2.3	-2.7	-2.8	-2.5	-2.8	-2.2	1.2	-1.8	-2.3	-1.4	-2.7	-2.6	-2.1	-2.8	-2.8	-2.5	-2.7	-2.8	-2.8
Basal metabolic rate	3.5	19.6	59.8	3.6	2.6	-4.1	2.1	3.6	4.2	3.6	4.7	2.6	4.0	4.2	3.8	4.6	-7.7	-2.1	4.2	-7.6	2.5	5.1	6.7	3.7	3.7	5.7	4.7	3.6	4.0
Leg fat-free mass (left)	3.4	18.2	52.7	3.5	2.6	-3.7	2.1	3.4	4.1	3.5	4.8	2.5	3.8	4.2	3.6	4.7	-7.3	-1.8	4.0	-7.2	2.4	5.0	6.4	3.7	3.6	5.5	4.5	3.5	3.9
Leg predicted mass (left)	3.4	18.0	52.3	3.5	2.6	-3.7	2.1	3.4	4.1	3.5	4.8	2.5	3.8	4.1	3.6	4.7	-7.2	-1.8	4.0	-7.2	2.4	4.9	6.4	3.6	3.6	5.4	4.5	3.5	3.8
Arm fat-free mass (right)	3.3	17.1	52.3	3.3	2.3	-3.8	1.8	3.4	4.0	3.4	4.4	2.3	3.8	4.0	3.6	4.1	-7.2	-2.0	3.8	-7.2	2.7	4.7	6.0	3.5	3.5	5.3	4.4	3.5	3.8
Leg pain on walking	3.3	4.2	8.9	-1.8	-2.0	-3.0	-2.3	-2.7	-2.0	-2.1	-1.4	-2.2	-2.0	-1.9	-2.3	-1.8	-0.9	-2.8	-1.4	-2.0	-2.1	-1.7	-0.8	-2.5	-2.2	-1.4	-1.7	-2.4	-2.0
Medication: Paracetamol	3.2	5.3	10.6	2.5	2.3	-0.8	1.6	2.2	2.3	2.4	2.1	2.2	2.2	2.5	2.2	2.4	-3.3	0.3	2.6	-2.7	2.0	2.5	2.8	2.0	2.1	2.8	2.6	2.1	2.2
Medication for cholesterol, blood pressure or diabetes	3.1	5.2	13.1	-2.3	-2.0	0.7	-1.1	-1.8	-2.4	-2.4	-2.5	-1.9	-2.4	-2.4	-2.4	-1.9	3.6	-0.2	-2.1	1.9	-2.4	-2.5	-2.8	-2.2	-2.3	-2.8	-2.7	-2.3	-2.4
Long-standing illness, disability or infirmity	3.1	4.7	8.2	2.2	2.0	0.6	1.7	2.2	2.4	2.4	2.9	2.2	2.4	2.3	2.4	2.0	-1.9	0.4	2.3	-0.5	2.5	2.4	2.2	2.2	2.3	2.4	2.5	2.5	2.3
Leg predicted mass (right)	3.1	16.3	50.0	3.1	2.3	-3.9	1.8	3.1	3.9	3.1	4.6	2.2	3.5	3.9	3.3	4.6	-7.1	-1.9	3.7	-7.0	2.0	4.7	6.3	3.5	3.3	5.2	4.1	3.2	3.5
Guilty feelings	3.1	4.6	7.9	-2.3	-2.6	-2.5	-2.1	-2.2	-2.2	-2.4	-2.1	-2.4	-2.4	-2.2	-2.4	-1.2	0.5	-2.5	-2.4	-1.2	-2.8	-2.0	-1.0	-2.0	-2.3	-1.8	-2.3	-2.3	-2.3
Pack years of smoking	3.1	4.6	7.2	2.0	1.7	0.6	1.5	2.1	2.4	2.4	2.2	1.8	2.6	2.2	2.5	1.4	-1.8	1.0	2.2	-1.0	2.7	2.4	2.2	2.3	2.5	2.4	2.6	2.6	2.6
Lung FEV1/FVC ratio	3.0	15.2	30.2	-3.1	-2.4	0.2	-2.5	-4.0	-3.7	-4.0	-3.7	-2.7	-4.7	-3.8	-4.3	-4.8	3.4	-0.4	-3.8	1.9	-3.4	-4.9	-5.5	-4.9	-4.7	-4.8	-4.5	-4.6	-4.7
Medication: Co-codamol	3.0	3.4	12.0	1.5	1.2	-1.5	0.5	1.9	1.5	1.7	1.5	1.4	1.6	1.6	1.7	1.8	-3.2	-1.1	1.9	-3.5	1.3	2.0	2.4	1.7	1.6	2.3	2.0	1.6	1.6
Hand grip strength (right)	3.0	8.2	13.4	2.6	2.5	-0.2	2.2	2.8	2.8	2.9	3.6	2.5	3.1	3.2	2.9	3.6	-2.9	0.4	2.8	-2.1	2.4	3.5	3.7	3.0	3.0	3.5	3.3	2.9	3.1
Worry too long after embarrassment	3.0	5.0	8.5	-2.1	-2.3	-0.8	-1.5	-2.4	-2.5	-2.5	-2.0	-2.2	-2.6	-2.4	-2.6	-1.9	1.9	-1.3	-2.4	0.3	-2.9	-2.4	-1.9	-2.2	-2.4	-2.4	-2.7	-2.6	-2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	3.0	3.9	6.2	-1.6	-1.7	-0.5	-1.2	-2.3	-1.9	-2.1	-1.9	-1.7	-2.5	-2.2	-2.3	-1.9	1.6	-0.2	-2.0	0.0	-2.3	-2.3	-2.2	-2.1	-2.4	-2.3	-2.4	-2.3	-2.5
Medication for pain relief, constipation, heartburn	3.0	5.2	7.9	-2.8	-2.3	-1.0	-2.2	-2.4	-2.4	-2.7	-2.2	-2.5	-2.3	-2.4	-2.4	-2.2	1.9	-1.4	-2.3	1.7	-2.4	-2.4	-2.1	-2.2	-2.3	-2.5	-2.5	-2.5	-2.3
Leg fat-free mass (right)	3.0	16.2	50.4	3.0	2.3	-4.0	1.8	3.1	3.8	3.1	4.6	2.1	3.4	3.9	3.3	4.6	-7.1	-1.9	3.7	-7.0	2.0	4.7	6.3	3.5	3.3	5.2	4.1	3.2	3.5
Lupus	2.9	4.3	47.6	0.5	1.0	1.4	1.0	3.4	1.4	1.3	-2.0	-0.6	1.9	1.1	1.7	1.4	0.5	6.9	0.5	-2.1	1.0	1.6	1.9	2.3	2.0	1.2	1.2	2.0	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.9	4.4	6.5	-2.2	-2.0	-1.5	-1.9	-2.1	-2.1	-2.3	-1.9	-2.1	-2.5	-2.2	-2.4	-1.5	1.3	-1.2	-2.1	-1.0	-2.4	-2.4	-2.0	-2.3	-2.5	-2.3	-2.5	-2.4	-2.5
Ever highly irritable/argumentative for 2 days	2.9	3.4	4.7	-2.1	-2.2	-0.9	-1.8	-1.9	-1.9	-2.1	-1.6	-2.1	-2.0	-2.0	-2.0	-1.7	1.6	-1.6	-2.1	0.7	-2.1	-1.9	-1.6	-1.7	-1.9	-2.0	-2.1	-1.9	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.9	3.5	6.0	1.8	1.6	0.2	1.2	2.4	2.0	2.2	1.8	1.9	2.0	1.9	2.2	1.8	-2.0	0.5	1.6	-0.6	2.5	1.9	1.5	2.2	2.0	2.0	2.2	2.4	2.0
Medication: Paracetamol	2.8	4.3	8.4	1.9	1.9	-1.1	1.1	2.1	2.0	2.2	1.9	1.8	2.2	2.3	2.1	2.0	-2.9	0.4	2.1	-2.5	2.2	2.3	2.5	1.8	2.0	2.6	2.4	2.1	2.2
Heel T-Score	2.7	21.6	43.6	-4.2	-3.2	2.0	-2.5	-4.6	-4.8	-4.8	-4.4	-3.4	-4.8	-4.6	-4.8	-5.7	6.4	-0.1	-4.3	4.4	-3.7	-5.5	-6.6	-5.1	-4.8	-6.0	-5.3	-4.9	-4.8
Relative age of first facial hair	2.7	5.6	8.4	2.4	2.7	0.3	2.2	2.1	2.6	2.4	1.5	2.1	2.6	2.6	2.4	2.2	-2.3	1.9	2.9	-2.3	2.1	2.7	2.9	2.4	2.5	2.8	2.6	2.4	2.6
Had menopause	2.7	3.3	4.3	2.1	1.8	1.1	1.9	2.0	2.0	2.1	1.5	1.7	1.9	2.0	2.0	1.6	-1.4	1.6	1.9	-0.9	1.7	2.0	1.9	2.0	2.0	2.0	2.0	2.0	2.0
Primary Biliary Cirrhosis	2.6	3.7	8.2	1.7	1.4	-0.2	1.5	2.2	2.1	1.8	2.4	1.4	1.9	2.2	1.9	2.6	-1.9	1.0	1.7	-2.9	1.2	2.2	2.6	2.1	1.9	2.2	1.9	1.9	1.9
Fluid intelligence score	2.6	5.4	11.9	2.9	2.7	0.4	1.7	2.8	2.5	2.6	3.5	3.1	2.3	2.5	2.3	1.7	-2.7	0.4	2.4	-0.7	3.0	2.1	1.6	1.4	2.0	2.5	2.7	2.2	2.2
Handedness (chirality/laterality): Left-handed	2.6	3.2	4.8	2.1	1.9	0.6	1.7	1.8	1.9	2.0	2.2	2.2	1.9	2.0	1.9	1.7	-1.4	1.4	2.0	-0.3	2.1	1.7	1.4	1.5	1.8	1.8	2.0	1.8	1.9
Diabetes diagnosed by doctor	2.6	4.2	9.2	2.3	1.9	-0.5	1.4	2.0	2.0	2.2	2.2	2.2	2.2	2.0	2.0	2.2	-3.0	-0.9	2.2	-1.3	2.0	2.2	2.4	1.7	2.0	2.5	2.3	1.9	2.2
Hair/balding pattern: Pattern 3	2.5	3.7	6.4	2.5	2.1	1.8	2.3	1.7	1.8	2.2	1.9	2.2	2.0	2.1	2.0	1.2	-1.2	2.1	1.7	0.2	2.1	2.0	1.6	1.7	2.0	2.0	2.2	1.9	2.0
Pulse wave Arterial Stiffness index	2.5	2.9	9.7	1.5	1.2	-1.6	0.8	1.4	1.4	1.6	0.9	1.0	1.3	1.5	1.6	2.0	-3.0	0.3	1.6	-3.1	0.6	2.0	2.6	2.0	1.4	2.2	1.8	1.5	1.3
Medication: Ventolin 100micrograms inhaler	2.5	3.2	5.7	1.2	1.4	1.1	1.8	1.7	1.3	1.9	1.9	1.3	2.2	1.8	1.9	2.0	-0.3	2.0	1.4	0.3	1.4	2.2	2.4	2.3	2.3	1.9	1.9	2.0	2.3
Pulse wave peak to peak time	2.5	2.9	10.1	-1.4	-1.2	1.8	-0.6	-1.4	-1.4	-1.6	-1.0	-1.0	-1.3	-1.5	-1.6	-1.9	3.1	-0.1	-1.5	3.2	-0.8	-2.0	-2.5	-2.0	-1.4	-2.2	-1.8	-1.6	-1.3
Chest pain or discomfort	2.5	3.6	6.5	1.6	1.7	-0.8	1.0	2.0	1.8	2.2	2.1	1.8	2.1	2.0	2.0	2.0	-2.6	-0.1	1.7	-1.5	2.4	2.0	1.9	1.7	1.9	2.3	2.4	2.1	2.0
Pack years adult smoking proportion	2.4	3.6	5.6	1.7	1.4	0.4	1.3	1.8	2.1	2.1	2.0	1.6	2.3	1.9	2.2	1.2	-1.6	0.8	1.7	-1.1	2.3	2.2	2.1	2.2	2.3	2.2	2.3	2.4	2.3
Father’s age at death	2.4	3.2	4.9	-1.6	-1.5	0.7	-0.8	-1.7	-1.8	-2.0	-1.8	-1.4	-2.0	-1.9	-1.9	-1.6	2.2	-0.0	-2.0	1.6	-2.0	-2.0	-2.1	-1.7	-1.9	-2.2	-2.2	-1.9	-2.0
Headache pain in last month	2.4	4.2	6.0	1.8	2.0	-0.8	1.1	2.2	2.0	2.2	2.5	1.8	2.3	2.2	2.2	2.4	-2.3	0.4	1.8	-1.4	2.2	2.2	2.3	1.9	2.1	2.4	2.4	2.2	2.3
Whole body fat-free mass	2.4	13.9	49.0	2.7	1.9	-4.1	1.4	2.9	3.4	2.8	3.9	1.8	3.3	3.5	3.0	3.8	-6.8	-2.0	3.2	-7.0	1.9	4.3	5.8	3.0	3.0	4.8	3.9	2.9	3.3
Whole body water mass	2.4	13.7	48.3	2.7	1.9	-4.0	1.4	2.8	3.4	2.8	3.9	1.8	3.3	3.5	3.0	3.8	-6.7	-2.0	3.2	-7.0	2.0	4.3	5.8	3.0	3.0	4.8	3.9	2.9	3.3
Alcohol intake versus 10 years previously	2.3	3.4	6.2	2.0	2.1	1.4	2.1	2.5	2.1	1.9	1.4	2.2	1.8	2.0	1.9	2.3	-0.9	1.8	2.1	-0.4	1.8	1.9	1.5	1.6	1.8	1.8	1.9	1.8	1.8
Crohns Disease (2017)	2.2	4.9	9.5	-2.3	-2.5	-2.5	-2.2	-2.3	-2.3	-2.4	-1.7	-2.1	-2.4	-2.3	-2.4	-2.6	-0.1	-3.1	-2.0	-1.5	-2.7	-2.0	-1.2	-2.2	-2.4	-1.7	-2.2	-2.5	-2.3
Irritable Bowel Disease (IBD)	2.2	5.2	12.7	-2.0	-2.8	-2.5	-2.1	-2.6	-2.5	-2.4	-1.3	-2.0	-2.5	-2.4	-2.5	-2.6	-0.1	-3.6	-2.1	-1.0	-3.0	-2.0	-1.1	-2.1	-2.5	-1.8	-2.2	-2.5	-2.5
Body Mass Index (BMI) (2010)	2.2	3.1	10.0	2.2	1.5	-0.3	1.3	0.9	1.7	1.8	1.6	1.7	1.6	1.7	1.6	0.7	-2.6	0.2	2.1	-3.2	1.6	1.9	2.0	1.5	1.6	2.1	2.0	1.6	1.6
HDL Cholesterol	2.2	3.7	9.4	-2.0	-1.7	0.9	-1.1	-1.7	-1.9	-2.0	-1.5	-1.6	-1.9	-1.8	-2.0	-1.4	3.1	0.4	-2.1	2.5	-1.6	-2.3	-2.6	-1.9	-1.8	-2.5	-2.3	-1.9	-1.9
Blood White Count	2.2	16.3	34.2	-2.5	-2.0	2.0	-1.5	-4.8	-3.9	-3.9	-3.5	-2.3	-4.3	-4.1	-4.3	-5.7	4.4	-0.5	-3.1	4.0	-3.3	-5.1	-5.8	-5.0	-4.5	-5.0	-4.8	-4.6	-4.4
Emphysema/chronic bronchitis	2.2	2.5	5.4	2.0	1.5	0.0	1.7	1.1	1.5	1.5	1.9	1.6	1.4	1.6	1.4	1.6	-2.1	-0.1	1.9	-1.6	0.8	1.9	2.3	1.5	1.5	2.0	1.6	1.3	1.4
Ever depressed for a whole week	2.2	2.7	4.5	-2.1	-2.0	-0.9	-1.7	-1.6	-1.8	-1.8	-1.3	-2.1	-1.5	-1.8	-1.7	-1.6	1.5	-0.9	-2.1	0.3	-1.4	-1.8	-1.5	-1.6	-1.6	-1.9	-1.8	-1.6	-1.5
Diabetes (self-reported)	2.1	3.3	7.7	2.1	1.5	-0.5	1.5	1.5	1.6	1.9	1.9	1.9	2.0	1.7	1.7	1.9	-2.8	-1.0	1.9	-1.2	1.5	2.1	2.5	1.6	1.8	2.3	2.0	1.6	2.0
Prospective memory result	2.1	2.6	5.1	-1.9	-1.8	-1.0	-1.2	-1.6	-1.8	-2.0	-1.1	-1.5	-1.8	-1.7	-2.0	-1.1	1.0	-1.4	-1.5	0.8	-2.3	-1.6	-1.0	-1.9	-1.8	-1.6	-1.9	-2.1	-1.8
Exposure to tobacco smoke outside home	2.1	2.8	9.0	1.9	1.3	-1.4	0.6	1.4	1.5	1.6	1.7	1.5	1.6	1.6	1.5	1.8	-3.0	-0.5	1.5	-2.3	1.6	1.7	2.0	1.1	1.4	2.0	1.8	1.4	1.6
Commuting to job workplace: Car/motor vehicle	2.1	2.3	7.3	-1.1	-1.3	-1.8	-1.8	-1.6	-1.6	-1.4	-0.8	-1.1	-1.7	-1.6	-1.7	-1.7	-0.8	-2.7	-1.1	-0.4	-1.0	-1.6	-1.6	-2.0	-1.8	-1.2	-1.2	-1.8	-1.7
Tinnitus: Yes, but not now, but have in the past	2.0	2.2	4.8	1.1	1.3	0.9	1.3	1.6	1.6	1.4	1.8	1.1	1.6	1.6	1.6	2.2	-0.4	1.5	1.3	0.4	1.2	1.6	1.6	1.8	1.7	1.5	1.5	1.6	1.6
Allergy	2.0	4.6	11.8	-1.9	-2.5	-3.4	-2.8	-2.4	-2.1	-2.0	-2.4	-2.6	-2.0	-2.2	-2.0	-2.3	-1.1	-2.6	-1.9	-2.3	-1.9	-1.8	-1.1	-2.0	-2.2	-1.4	-1.7	-2.0	-2.0
Medication: Ramipril	2.0	2.5	7.3	1.7	1.4	-0.7	1.0	1.8	1.7	1.7	1.0	1.3	1.6	1.6	1.6	2.0	-2.7	-0.0	1.7	-1.9	1.6	1.6	1.8	1.2	1.4	1.9	1.7	1.5	1.5
Happiness	2.0	2.4	6.9	-2.0	-1.1	0.6	-0.8	-1.7	-1.2	-1.6	-2.0	-1.4	-1.4	-1.5	-1.4	-1.4	2.6	0.6	-1.9	2.0	-1.5	-1.6	-1.6	-1.3	-1.3	-1.9	-1.8	-1.4	-1.4
Ever had hysterectomy (womb removed)	1.9	2.2	5.4	1.6	1.1	-0.8	0.5	1.6	1.6	1.6	1.4	0.9	1.5	1.4	1.6	1.5	-2.3	0.5	1.2	-2.0	1.9	1.5	1.4	1.4	1.3	1.7	1.8	1.7	1.4
Illnesses of father: None of the above (group 1)	1.9	2.4	7.7	-1.5	-1.4	-0.3	-0.7	-1.0	-1.5	-1.9	-2.0	-1.8	-2.0	-1.4	-1.9	-0.2	1.6	0.5	-1.5	0.3	-2.8	-1.3	-0.8	-1.2	-1.6	-1.5	-1.9	-1.9	-1.9
Impedance of whole body	1.9	9.7	46.6	-1.0	-0.3	5.9	1.3	-1.7	-2.0	-1.8	-3.9	-0.2	-2.3	-2.3	-2.0	-2.2	6.8	2.9	-1.5	6.8	-2.3	-2.7	-3.9	-1.6	-1.8	-3.5	-3.1	-2.1	-2.3
Impedance of leg (right)	1.8	8.6	39.8	-1.0	-0.5	5.3	0.8	-1.6	-2.1	-1.6	-4.0	-0.2	-2.0	-2.3	-1.8	-2.9	6.3	2.5	-1.5	6.0	-1.4	-2.8	-4.3	-1.9	-1.8	-3.5	-2.8	-1.9	-2.0
Impedance of arm (right)	1.8	8.5	41.3	-1.0	-0.3	5.5	1.3	-1.7	-2.0	-1.8	-3.7	-0.3	-2.2	-2.1	-2.0	-1.7	6.4	2.8	-1.4	6.1	-2.6	-2.5	-3.3	-1.5	-1.8	-3.2	-3.0	-2.2	-2.2
Impedance of arm (left)	1.8	8.2	40.8	-0.8	-0.1	5.7	1.6	-1.6	-1.7	-1.7	-3.5	-0.1	-2.2	-1.9	-1.9	-1.4	6.4	3.0	-1.2	6.2	-2.5	-2.3	-3.2	-1.4	-1.6	-3.1	-2.9	-2.1	-2.1
Medication: Aspirin	1.8	2.4	5.8	2.0	1.5	0.2	0.9	1.1	1.1	1.9	1.6	1.6	1.8	1.6	1.6	0.5	-2.1	1.0	1.6	-1.4	2.4	1.5	1.1	1.1	1.6	1.7	2.0	1.6	1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.8	2.0	3.9	-0.9	-0.8	-0.5	-1.2	-1.3	-1.2	-1.7	-0.9	-1.2	-1.8	-1.4	-1.7	-1.1	0.5	-1.3	-1.0	-0.2	-1.5	-1.8	-1.6	-2.0	-1.8	-1.6	-1.7	-1.8	-1.8
Eye problems/disorders: Glaucoma	1.8	2.1	6.6	-1.7	-1.6	0.0	-1.2	-1.4	-1.8	-1.4	-2.6	-1.7	-1.3	-1.7	-1.4	-1.2	1.9	-0.4	-1.5	1.2	-1.4	-1.5	-1.4	-1.0	-1.2	-1.6	-1.5	-1.3	-1.3
Impedance of leg (left)	1.7	8.1	36.0	-1.2	-0.7	4.9	0.7	-1.7	-2.1	-1.7	-3.9	-0.5	-2.2	-2.3	-1.9	-2.7	6.0	2.3	-1.6	5.8	-1.7	-2.7	-4.0	-1.8	-1.8	-3.4	-2.8	-2.0	-2.2
Peak expiratory flow (PEF)	1.7	4.0	6.1	-2.5	-2.2	-2.0	-2.1	-2.1	-2.1	-2.3	-2.1	-2.3	-2.2	-2.0	-2.0	-1.7	0.5	-2.1	-2.4	0.1	-2.3	-1.9	-1.4	-1.7	-2.1	-1.9	-2.1	-1.9	-2.2
Neck or shoulder pain in last month	1.7	2.4	6.4	1.5	1.3	-0.8	1.2	1.3	1.6	1.2	2.1	1.2	1.2	1.6	1.2	1.6	-2.4	-1.0	1.9	-2.5	0.6	1.7	2.2	1.2	1.2	1.9	1.5	1.1	1.2
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.0	8.3	-0.7	-1.2	-2.5	-1.2	-1.3	-1.1	-1.2	-0.8	-1.2	-1.3	-1.2	-1.3	-1.4	-1.6	-2.9	-0.7	-2.4	-1.4	-0.9	-0.3	-1.5	-1.5	-0.6	-0.9	-1.4	-1.3
Osteoporosis (self-reported)	1.7	2.1	4.0	2.0	1.2	0.8	1.3	1.4	1.7	1.4	0.9	1.1	1.8	1.5	1.5	1.1	-1.0	1.4	1.6	-1.1	1.2	1.7	2.0	1.5	1.6	1.7	1.5	1.5	1.8
Supplements: Zinc	1.6	1.8	4.0	-0.6	-0.9	-0.4	-0.6	-1.5	-1.5	-1.5	-0.6	-0.8	-1.8	-1.1	-1.8	-1.1	0.5	-0.9	-0.9	-0.2	-1.8	-1.5	-1.4	-1.9	-1.8	-1.4	-1.6	-2.0	-1.8
Trunk fat-free mass	1.6	9.3	39.2	1.9	1.2	-3.9	0.9	2.2	2.5	2.1	2.9	1.1	2.6	2.7	2.3	2.8	-5.8	-1.8	2.4	-6.3	1.5	3.5	4.9	2.3	2.4	3.9	3.1	2.2	2.6
Trunk predicted mass	1.6	8.9	38.2	1.9	1.1	-3.9	0.9	2.1	2.5	2.1	2.8	1.1	2.6	2.6	2.2	2.7	-5.7	-1.8	2.4	-6.2	1.4	3.4	4.8	2.2	2.3	3.8	3.0	2.1	2.6
Number of full brothers	1.6	2.0	12.1	1.5	0.8	-1.8	0.1	1.2	1.3	1.0	0.7	0.7	1.0	1.0	1.0	1.0	-3.1	-0.5	1.4	-3.5	1.1	1.1	1.6	0.6	0.7	1.6	1.3	0.9	1.0
Age at first live birth	1.6	2.8	9.9	-1.5	-0.6	1.7	-0.4	-1.4	-1.4	-1.7	-2.3	-1.1	-1.6	-1.4	-1.6	-1.3	3.1	1.6	-1.1	2.3	-1.7	-1.7	-2.0	-1.3	-1.4	-2.1	-1.9	-1.6	-1.6
Breast Cancer	1.5	3.6	6.7	2.4	1.8	-0.1	0.9	1.7	1.9	2.2	1.9	1.7	1.9	2.0	2.1	1.3	-2.3	1.4	2.0	-1.9	2.6	1.8	1.4	1.7	1.8	2.1	2.4	2.1	1.9
Smoking Status	1.5	3.6	14.5	2.2	2.6	-1.4	1.0	1.2	2.0	1.5	2.4	2.0	1.3	1.8	1.3	1.0	-3.8	-1.4	2.4	-3.7	1.9	1.4	1.3	0.1	0.9	2.0	1.9	0.9	1.3
Hearing difficulty/problems with background noise	1.5	2.5	4.7	1.3	2.1	1.3	1.4	2.2	1.9	1.6	1.4	1.6	1.8	1.7	1.8	1.7	-0.2	1.0	1.7	0.6	1.8	1.4	1.0	1.6	1.7	1.3	1.5	1.8	1.7
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.5	6.5	-1.8	-1.7	0.6	-1.1	-2.2	-2.0	-2.1	-2.4	-1.8	-1.7	-1.9	-2.0	-2.6	2.5	-0.2	-1.6	1.1	-1.8	-2.0	-2.0	-1.9	-1.7	-2.2	-2.1	-2.0	-1.7
Blood clot in the leg (DVT)	1.5	1.9	4.8	1.2	1.7	0.9	1.0	1.4	1.5	1.6	1.6	1.4	1.5	1.6	1.5	1.0	-0.4	2.2	1.2	-0.1	2.1	1.2	0.5	1.1	1.4	1.2	1.5	1.5	1.4
Illnesses of siblings: Diabetes	1.5	1.8	4.8	1.3	0.8	-0.8	0.3	1.0	1.5	1.4	1.6	0.9	1.4	1.3	1.4	1.5	-2.2	-1.0	1.1	-1.2	1.5	1.4	1.6	1.3	1.3	1.6	1.5	1.6	1.4
Supplements: Fish oil (including cod liver oil)	1.5	2.0	4.2	-2.0	-1.2	-0.7	-1.4	-1.1	-1.5	-1.5	-1.6	-1.4	-1.5	-1.5	-1.5	-1.7	1.1	-0.4	-1.4	0.4	-0.9	-1.6	-1.9	-1.8	-1.5	-1.6	-1.3	-1.5	-1.5
Illnesses of father: High blood pressure	1.5	1.9	8.4	1.2	1.1	-1.6	0.1	0.6	1.2	1.3	1.5	1.2	1.0	1.1	1.2	0.3	-2.8	-1.6	1.4	-2.9	1.5	1.0	1.1	0.7	0.8	1.4	1.3	1.2	1.0
Verbal and Numeric Reasoning (VNR)	1.4	3.4	10.1	2.2	2.2	0.6	1.4	1.7	2.2	2.0	3.2	2.6	1.8	2.0	1.9	1.1	-1.8	0.9	1.8	0.2	2.5	1.7	1.2	1.2	1.6	1.9	2.1	1.8	1.8
Type 2 Diabetes (T2D) (2018)	1.4	2.6	10.2	1.6	1.0	-1.7	0.7	1.3	1.3	1.3	1.3	1.0	1.2	1.3	1.1	2.0	-3.2	-1.6	1.6	-2.7	0.7	1.8	2.4	1.2	1.2	2.0	1.6	1.0	1.3
Had other major operations	1.4	1.8	5.5	1.0	1.0	-1.1	1.1	0.7	1.3	1.1	1.0	1.1	1.1	1.2	1.0	1.2	-2.3	-1.1	1.5	-2.0	0.4	1.7	2.3	1.0	1.1	1.8	1.3	0.9	1.2
Illnesses of mother	1.4	1.8	4.1	-1.4	-1.2	0.2	-0.8	-1.7	-1.4	-1.3	-1.0	-1.1	-1.4	-1.4	-1.2	-1.2	2.0	-0.8	-1.5	1.8	-1.4	-1.4	-1.5	-0.8	-1.2	-1.6	-1.5	-1.1	-1.3
Medication: Allopurinol	1.4	1.9	9.4	-1.1	-0.7	1.6	-0.5	-0.6	-0.9	-1.1	-1.3	-0.6	-1.3	-1.2	-1.1	-0.9	2.4	0.1	-0.9	3.1	-0.7	-1.6	-2.2	-1.3	-1.2	-1.8	-1.4	-1.1	-1.3
Family relationship satisfaction	1.4	1.8	6.2	1.5	1.6	2.1	2.0	1.2	1.2	1.3	0.9	1.6	1.2	1.3	1.2	0.8	0.4	2.5	1.0	1.5	1.3	1.0	0.6	0.9	1.2	0.9	1.0	1.1	1.2
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	4.2	1.2	1.7	0.9	0.9	1.4	1.5	1.6	1.5	1.4	1.5	1.6	1.5	0.9	-0.5	2.0	1.2	-0.0	2.0	1.1	0.4	1.0	1.3	1.1	1.5	1.5	1.4
HbA1C	1.3	1.5	3.3	0.6	0.9	0.1	0.8	1.7	1.1	1.6	1.3	0.8	1.5	1.2	1.3	1.8	0.3	1.2	0.9	0.9	1.8	1.1	0.5	1.3	1.4	1.0	1.3	1.4	1.5
Taking other prescription medications	1.3	2.1	3.4	1.5	1.3	0.8	1.2	1.6	1.6	1.6	1.7	1.3	1.6	1.4	1.6	1.9	-1.1	-0.2	1.4	-0.2	1.3	1.6	1.6	1.7	1.6	1.6	1.5	1.6	1.6
Qualifications: A levels/AS levels or equivalent	1.3	3.0	19.1	0.9	1.6	4.2	2.0	1.0	0.8	0.9	0.5	1.6	0.9	1.0	1.0	0.6	2.9	3.3	0.6	4.4	1.2	0.3	-0.8	0.9	1.0	-0.2	0.3	1.0	0.9
Age at last live birth	1.3	1.8	3.0	-1.0	-0.5	0.6	-0.5	-1.5	-1.1	-1.5	-1.5	-0.9	-1.5	-1.1	-1.6	-1.5	1.7	0.7	-0.8	0.7	-1.5	-1.6	-1.6	-1.7	-1.5	-1.6	-1.7	-1.7	-1.6
Back pain experienced in last month	1.3	1.9	4.3	1.4	1.5	0.2	1.4	1.5	1.7	1.3	2.1	1.4	1.4	1.4	1.4	2.0	-1.1	-0.2	1.2	-0.1	0.9	1.5	1.8	1.4	1.4	1.5	1.3	1.4	1.4
Medication: Metformin	1.2	1.7	3.1	1.5	1.6	0.1	1.3	1.0	1.3	1.3	1.4	1.4	1.4	1.4	1.2	1.6	-1.6	-0.1	1.8	-0.4	1.0	1.5	1.6	1.0	1.3	1.5	1.4	1.1	1.4
Glaucoma (self-reported)	1.2	1.5	3.8	-1.6	-1.5	-0.5	-1.2	-1.1	-1.5	-1.1	-2.0	-1.6	-0.9	-1.4	-1.0	-1.1	1.5	-0.6	-1.4	1.5	-1.2	-1.0	-0.8	-0.5	-0.8	-1.2	-1.2	-0.9	-0.9
Qualifications: College or University degree	1.2	3.7	21.6	-0.4	-0.1	3.8	0.3	-1.2	-0.9	-1.0	-1.2	-0.3	-0.9	-0.9	-0.9	-1.6	4.1	3.0	-1.4	4.7	-0.3	-1.7	-2.8	-1.2	-0.9	-2.2	-1.6	-0.9	-0.9
Angina (self-reported)	1.2	1.6	6.5	-0.7	-1.2	-2.1	-1.3	-1.0	-1.1	-1.0	-0.4	-1.0	-1.3	-1.0	-1.2	-0.8	-1.4	-2.4	-0.6	-2.5	-1.0	-0.9	-0.5	-1.3	-1.4	-0.5	-0.7	-1.2	-1.3
Medication: Seretide 50 evohaler	1.2	1.3	3.1	0.9	1.1	1.2	1.2	1.3	1.0	1.2	1.2	1.6	1.3	1.2	1.3	0.9	0.1	0.6	0.9	1.8	1.5	1.0	0.6	1.1	1.3	0.9	1.1	1.3	1.3
Number of operations (self-reported)	1.2	1.8	7.9	1.3	0.8	-1.2	0.7	0.9	1.2	1.1	1.2	1.3	0.7	1.0	1.0	1.6	-2.8	-1.5	1.3	-2.3	0.5	1.5	1.9	1.1	0.8	1.7	1.3	1.0	0.7
Depression (Nagel 2018)	1.1	1.6	5.0	-1.7	-1.2	-1.9	-2.2	-1.1	-1.0	-1.3	-0.4	-1.7	-1.1	-1.2	-1.2	-0.6	0.0	-1.6	-1.5	-0.9	-0.6	-1.4	-1.3	-1.3	-1.3	-1.2	-1.1	-0.9	-1.2
Blood Eosinophil Count	1.1	8.4	68.1	-0.4	0.8	5.6	0.8	-1.7	-0.9	-1.2	-1.4	0.9	-1.4	-1.6	-1.3	-2.8	5.4	2.2	-1.0	8.2	0.4	-2.8	-5.0	-2.6	-1.7	-3.1	-2.0	-1.6	-1.5
Hypothyroidism (self reported)	1.1	2.6	5.1	-1.5	-1.4	-0.6	-1.1	-1.3	-1.5	-1.9	-2.2	-1.7	-2.0	-1.7	-1.9	-0.6	1.2	-0.8	-1.4	0.5	-2.3	-1.6	-1.3	-1.7	-1.9	-1.7	-1.9	-2.0	-2.0
Angina	1.1	1.4	6.4	-0.7	-1.2	-2.1	-1.4	-1.0	-1.1	-0.9	-0.3	-1.0	-1.1	-0.9	-1.1	-0.8	-1.3	-2.3	-0.6	-2.5	-0.9	-0.8	-0.3	-1.1	-1.2	-0.4	-0.6	-1.1	-1.1
Diabetes (mother)	1.1	1.4	7.5	1.1	0.3	-1.7	0.2	1.0	1.0	0.7	0.6	0.4	0.8	0.9	0.8	1.3	-2.6	-1.1	1.1	-2.7	0.5	1.1	1.7	0.7	0.7	1.4	1.0	0.8	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	6.4	-0.8	-0.9	-2.5	-1.9	-1.1	-1.0	-0.9	-0.3	-1.3	-0.9	-1.0	-1.0	-0.8	-1.2	-1.9	-1.0	-2.0	-0.4	-1.0	-0.7	-1.4	-1.2	-0.6	-0.7	-1.0	-1.0
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	5.5	1.9	1.5	-0.6	0.5	0.5	1.5	1.4	1.6	1.4	1.2	1.2	1.3	-0.5	-2.3	0.1	1.5	-1.8	1.9	1.1	0.9	0.7	1.0	1.5	1.6	1.2	1.1
Medication: Lisinopril	1.1	1.4	5.0	1.1	0.9	-0.2	1.0	0.8	1.0	1.1	1.1	1.0	1.1	1.1	1.0	1.2	-1.8	0.2	1.1	-2.2	0.6	1.3	1.8	1.1	1.1	1.4	1.2	0.9	1.2
Heart disease (siblings)	1.1	1.3	10.4	0.1	-0.4	-3.0	-1.2	0.2	0.1	0.0	0.5	-0.3	-0.1	0.0	-0.1	0.4	-2.9	-1.9	-0.0	-3.2	0.1	0.1	0.7	-0.3	-0.3	0.7	0.4	-0.1	-0.1
Major Depression (MDD)	1.0	1.2	2.2	-1.4	-1.4	-0.5	-0.8	-1.1	-1.4	-1.4	-0.3	-0.8	-0.9	-1.1	-1.2	-0.8	1.1	-1.0	-1.5	0.4	-1.0	-1.2	-1.0	-1.4	-1.1	-1.2	-1.2	-1.2	-0.9
Past tobacco smoking	1.0	1.8	6.7	-1.9	-2.0	0.7	-1.0	-0.3	-1.3	-1.1	-1.6	-1.8	-0.7	-1.2	-0.8	0.0	2.6	1.2	-1.8	2.6	-1.2	-0.9	-0.6	-0.0	-0.5	-1.3	-1.2	-0.5	-0.7
Mouth/teeth dental problems: Loose teeth	1.0	1.2	8.5	1.2	0.4	-1.5	0.4	0.0	0.3	0.2	0.9	0.5	0.1	0.3	0.0	0.6	-2.6	-1.7	1.0	-2.9	-0.5	0.8	1.6	-0.1	0.1	1.1	0.6	-0.2	0.2
Smoking status: Previous	1.0	1.4	4.6	1.9	2.1	-0.2	1.0	0.4	1.4	1.1	1.5	1.8	0.6	1.1	0.8	0.1	-2.1	-0.6	1.8	-1.9	1.3	0.7	0.3	0.0	0.4	1.1	1.1	0.5	0.6
Hearing aid user	1.0	1.2	6.5	0.7	0.8	-1.6	-0.5	0.5	1.0	0.9	1.4	0.3	0.8	0.9	0.9	0.7	-2.5	-0.4	0.9	-1.9	1.2	0.9	1.0	0.6	0.6	1.3	1.2	0.9	0.8
Alcohol drinker status: Previous	1.0	1.1	6.9	0.7	0.2	-2.0	-0.4	0.5	0.6	0.5	0.9	0.3	0.7	0.5	0.5	0.9	-2.6	-2.0	0.5	-2.2	0.5	0.7	1.3	0.3	0.4	1.2	0.8	0.4	0.7
Age at First Birth	0.9	1.3	4.1	-0.9	-0.8	1.1	-0.2	-1.2	-1.2	-1.0	-1.3	-1.0	-1.0	-1.1	-1.2	-1.1	2.0	1.4	-1.2	1.1	-1.1	-1.1	-1.2	-0.8	-0.9	-1.3	-1.3	-1.0	-1.0
Current tobacco smoking	0.9	1.4	6.1	0.8	0.8	-1.5	0.2	0.9	1.1	0.9	1.4	0.8	0.9	1.0	0.9	1.1	-2.5	-1.9	1.1	-2.0	1.0	1.1	1.3	0.3	0.7	1.4	1.2	0.7	0.9
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.6	-1.5	-1.5	-1.3	-1.4	-0.8	-0.9	-1.1	-0.3	-1.5	-1.0	-1.0	-1.0	-0.3	0.3	-1.6	-1.3	0.0	-0.9	-1.0	-0.6	-0.9	-1.0	-1.0	-1.1	-0.9	-1.0
Birth weight	0.9	1.9	11.4	1.2	0.9	-1.6	0.3	0.5	1.0	0.9	1.5	0.8	0.8	1.3	0.7	0.8	-2.7	-1.9	1.5	-3.4	0.4	1.2	1.8	0.7	0.7	1.5	1.2	0.6	0.9
Health satisfaction	0.9	1.1	5.4	0.2	-0.2	-2.2	-0.9	0.5	0.8	0.7	-0.1	-0.2	0.9	0.4	0.9	0.8	-2.2	-1.3	0.4	-2.3	1.3	0.6	0.9	0.6	0.6	0.9	1.0	1.1	0.9
Medication: Blood pressure	0.9	1.6	9.8	0.9	0.4	-1.8	-0.1	0.3	0.8	0.8	1.1	0.2	0.8	0.9	0.7	1.1	-3.1	-1.2	1.0	-2.8	0.3	1.2	2.0	0.7	0.7	1.6	1.1	0.6	0.8
Medication: Aspirin	0.9	1.2	3.6	1.3	0.8	-0.3	0.2	0.8	0.6	1.3	0.9	0.9	1.3	1.1	1.1	0.2	-1.9	0.7	1.1	-1.6	1.9	1.0	0.7	0.6	1.1	1.2	1.5	1.1	1.3
Risk taking	0.9	1.3	3.5	1.3	1.2	0.3	0.8	0.6	1.3	1.4	1.0	1.5	1.5	1.2	1.4	0.3	-1.0	0.7	1.2	0.7	1.9	1.0	0.7	0.7	1.2	1.2	1.3	1.3	1.5
Intelligence (Savage-Jansen 2018)	0.8	2.4	5.9	1.9	2.3	1.9	1.6	1.6	1.7	1.5	2.4	2.4	1.3	1.6	1.4	0.8	-0.5	1.3	1.5	2.0	2.0	1.1	0.3	0.7	1.2	1.1	1.4	1.3	1.2
Ulcerative Colitis (UC)	0.8	1.6	4.8	-0.6	-1.7	-1.1	-0.8	-1.7	-1.4	-1.2	-0.4	-0.7	-1.5	-1.4	-1.4	-1.4	0.1	-2.2	-1.2	0.3	-1.8	-1.1	-0.7	-1.1	-1.4	-1.0	-1.2	-1.4	-1.5
LDL Cholesterol	0.8	1.3	4.8	1.1	0.7	-1.3	-0.2	1.1	0.8	1.3	1.4	0.7	1.3	1.0	1.2	0.2	-2.2	0.3	0.5	-0.9	1.6	1.2	1.2	0.9	1.1	1.4	1.5	1.3	1.2
High blood pressure (mother)	0.8	1.1	8.3	0.5	0.2	-1.7	-0.2	0.9	0.4	0.4	0.9	0.1	0.6	0.6	0.3	0.3	-2.2	-1.2	0.8	-2.9	0.3	0.9	1.5	0.1	0.5	1.2	0.9	0.2	0.6
Pulse wave reflection index	0.8	0.9	8.6	0.4	-0.2	-2.1	-0.7	0.2	0.3	0.3	0.1	-0.3	0.1	0.1	0.4	0.6	-2.3	-1.0	0.2	-2.9	0.0	0.6	1.0	0.6	0.1	0.9	0.6	0.4	0.1
Heart disease (mother)	0.8	1.0	5.0	-0.4	-0.6	-1.0	-1.1	-0.9	-0.6	-1.0	-0.7	-0.8	-1.1	-1.0	-1.0	-1.0	-0.9	-2.2	-0.3	-0.9	-0.6	-1.1	-1.0	-1.4	-1.3	-0.7	-0.8	-1.1	-1.1
Bipolar Disorder (2018)	0.7	1.1	2.9	1.2	1.1	1.7	1.4	1.2	1.0	0.9	1.5	1.3	0.9	1.2	0.7	1.4	0.2	1.4	1.1	0.3	0.6	0.9	0.7	0.5	0.9	0.7	0.7	0.6	0.9
Allergy or Eczema	0.7	1.9	12.4	0.6	1.2	3.5	1.8	0.9	0.9	0.4	0.9	1.2	0.3	0.6	0.5	0.9	2.4	2.7	0.6	3.2	0.3	0.0	-0.6	0.5	0.5	-0.4	-0.1	0.5	0.3
Systolic blood pressure, automated reading	0.7	2.1	21.7	0.1	-0.4	-3.0	-0.9	0.2	0.1	0.5	0.8	-0.3	0.4	0.4	0.3	0.2	-3.3	-1.3	0.4	-4.7	0.1	0.9	1.8	0.4	0.3	1.3	0.9	0.3	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	4.3	-1.1	-1.0	0.1	-0.9	-1.4	-1.4	-1.3	-1.7	-1.0	-1.0	-1.2	-1.2	-2.1	1.4	-0.4	-1.0	0.7	-0.8	-1.4	-1.6	-1.3	-1.1	-1.5	-1.3	-1.2	-1.0
Mouth/teeth dental problems	0.7	1.1	5.3	-1.0	-0.6	1.5	0.0	-0.3	-0.9	-0.8	-1.3	-0.6	-0.8	-0.7	-0.7	-0.4	2.3	1.5	-0.9	2.1	-1.0	-0.9	-1.2	-0.4	-0.6	-1.2	-1.1	-0.7	-0.8
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	5.8	-0.3	0.2	2.3	0.7	-0.3	-0.3	-0.3	-0.2	0.1	-0.1	-0.2	-0.2	-0.1	2.3	1.8	-0.6	2.4	-0.1	-0.5	-0.9	-0.1	-0.1	-0.8	-0.6	-0.1	-0.1
Pulse rate	0.7	1.2	3.5	0.8	1.2	1.4	1.6	1.0	1.2	0.9	0.3	0.8	0.9	1.0	1.0	1.7	0.1	1.9	0.9	0.2	0.1	1.1	1.4	1.5	1.1	0.9	0.7	0.9	0.9
Medication: Lansoprazole	0.7	0.8	2.2	0.9	0.4	-0.5	-0.0	1.3	0.7	0.9	1.4	0.6	1.0	0.8	0.8	1.1	-1.5	-0.2	0.6	-0.8	1.4	0.8	0.7	0.4	0.8	1.0	1.2	0.9	0.9
Lung cancer (father)	0.7	0.8	4.1	-0.8	-0.9	-0.5	0.2	-0.6	-0.7	-1.0	-0.3	-0.6	-1.2	-0.7	-1.2	0.2	0.7	-0.3	-0.5	0.6	-2.0	-0.6	0.0	-0.9	-1.0	-0.6	-1.2	-1.4	-1.1
Gout (self-reported)	0.7	0.9	5.0	-0.5	0.0	1.7	0.1	-0.2	-0.2	-0.7	-0.9	-0.3	-0.7	-0.6	-0.7	-0.4	1.9	0.9	-0.3	2.2	-0.4	-1.0	-1.4	-1.1	-0.7	-1.2	-1.0	-0.8	-0.7
Had major operations	0.7	0.8	5.8	1.5	0.7	-0.6	0.4	0.6	0.8	0.6	0.3	1.0	0.3	0.5	0.5	0.4	-2.1	-0.2	1.0	-2.4	0.5	0.5	0.6	0.2	0.2	0.9	0.6	0.4	0.3
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	4.8	0.7	0.7	2.2	0.9	1.1	0.5	0.7	0.3	0.6	0.8	0.5	0.7	0.2	1.3	1.6	0.4	1.7	1.1	0.2	-0.5	0.4	0.7	-0.0	0.4	0.7	0.8
Schizophrenia vs Biploar Disorder	0.6	0.8	1.5	-0.7	-0.9	-0.3	-0.9	-0.9	-0.8	-0.8	-0.9	-1.0	-1.1	-1.0	-0.8	-0.6	0.4	-0.8	-1.2	0.9	-0.9	-1.0	-0.9	-0.5	-1.0	-0.9	-0.9	-0.6	-1.1
Bipolar Disorder (2011)	0.6	0.6	8.0	-0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.2	-0.3	2.8	0.7	-0.4	-1.2	0.1	0.3	-0.8	-0.3	0.3	0.5
Ulcerative Colitis	0.6	0.9	4.0	-0.3	-1.5	-1.4	-1.1	-1.2	-1.0	-0.6	0.4	-0.6	-0.9	-0.9	-0.8	-1.2	-0.4	-2.0	-1.2	0.8	-0.7	-0.7	-0.5	-0.7	-0.9	-0.6	-0.6	-0.8	-0.9
Chronotype (morning person)	0.6	1.3	3.6	-1.2	-1.5	-1.9	-1.4	-1.3	-1.2	-1.1	-0.9	-1.4	-1.2	-1.2	-1.2	-0.5	-0.5	-1.7	-1.2	-0.6	-1.1	-0.9	-0.5	-1.1	-1.2	-0.7	-0.8	-1.1	-1.2
Average weekly spirits intake	0.6	0.7	1.7	0.3	0.5	-0.0	0.5	0.8	0.9	1.0	0.7	0.7	1.0	0.8	1.1	0.9	-0.6	-0.3	0.8	-0.1	0.8	1.0	1.0	1.3	1.1	0.9	0.9	1.2	1.0
Diabetes (father)	0.6	0.7	1.5	-0.6	-0.7	0.8	0.0	-0.6	-0.8	-0.8	-0.7	-0.7	-1.2	-0.9	-0.9	-0.5	1.2	-0.1	-0.7	0.3	-1.2	-1.0	-1.1	-0.6	-1.0	-1.1	-1.1	-0.9	-1.2
Hayfever, allergic rhinitis or eczema	0.6	1.3	8.6	0.2	0.7	2.9	1.4	0.4	0.2	-0.3	0.3	0.7	-0.5	0.0	-0.3	0.6	2.5	1.7	0.1	2.7	-0.5	-0.6	-1.1	-0.3	-0.3	-0.9	-0.8	-0.4	-0.5
Number of live births	0.6	0.9	4.8	-0.7	-0.8	-1.4	-0.8	-0.9	-0.6	-0.8	-1.0	-1.1	-1.0	-0.8	-0.9	-0.9	-0.7	-0.6	-0.7	-2.2	-1.0	-0.6	-0.3	-0.8	-1.0	-0.4	-0.7	-0.9	-1.0
Noisy workplace	0.6	0.7	1.6	-1.1	-1.0	-1.3	-1.1	-1.0	-0.8	-0.8	-0.8	-1.1	-0.7	-0.9	-0.7	-1.0	-0.1	-1.1	-0.7	-1.0	-0.7	-0.7	-0.4	-0.7	-0.8	-0.6	-0.6	-0.7	-0.7
Shortness of breath walking on level ground	0.6	0.7	4.0	0.3	-0.0	-2.0	-0.6	0.3	0.5	0.5	0.7	0.3	0.3	0.2	0.4	-0.0	-2.0	-1.3	0.6	-2.0	0.9	0.2	0.3	0.1	0.1	0.6	0.6	0.5	0.3
Bipolar Disorder or Schizophrenia	0.5	1.2	6.2	1.3	1.2	2.5	1.6	1.0	0.8	0.5	1.2	1.3	0.3	0.8	0.3	1.4	0.9	2.1	0.9	1.8	0.1	0.5	0.3	0.2	0.5	0.3	0.2	0.2	0.3
Waist Hip Ratio (WHR)	0.5	2.4	8.3	-1.2	-0.7	1.1	0.3	-1.3	-1.4	-1.6	-2.6	-0.6	-1.7	-1.6	-1.8	-0.6	2.2	-0.4	-1.0	1.6	-2.9	-1.3	-0.8	-1.1	-1.4	-1.6	-2.1	-2.0	-1.7
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.4	0.7	0.7	-0.1	0.4	0.9	1.0	0.8	0.9	0.7	0.7	0.8	0.9	1.2	-1.0	0.3	0.9	-0.4	0.9	0.8	0.8	0.7	0.7	0.9	0.9	0.9	0.7
Vitamin and mineral supplements	0.5	0.7	2.5	-0.8	-0.6	0.6	-0.3	-0.4	-1.1	-0.5	-1.0	-0.4	-0.7	-0.8	-0.7	-1.0	1.4	1.3	-1.1	1.6	-0.5	-0.9	-1.1	-0.6	-0.6	-0.9	-0.8	-0.7	-0.7
Age when periods started (menarche)	0.5	1.2	7.1	-0.1	0.2	2.4	1.2	0.5	0.3	-0.2	-0.4	-0.1	-0.2	0.1	-0.0	0.9	2.5	2.4	-0.3	2.7	-1.1	-0.0	-0.0	0.7	0.2	-0.5	-0.7	-0.0	-0.1
Qualifications: CSEs or equivalent	0.5	0.7	9.7	0.5	0.2	-1.0	0.6	-0.1	0.2	-0.1	0.6	0.2	-0.1	0.3	-0.2	0.8	-1.2	-1.0	0.8	-3.1	-0.8	0.4	1.1	0.0	-0.1	0.6	-0.0	-0.3	-0.1
Medication: Atenolol	0.5	0.6	3.2	-0.8	-0.4	-1.8	-1.3	-0.1	-0.4	-0.6	-0.7	-1.0	-0.5	-0.4	-0.6	0.1	-1.2	-1.3	-0.1	-1.4	-0.6	-0.3	0.1	-0.7	-0.6	-0.1	-0.4	-0.6	-0.5
Sitting height	0.5	3.3	10.2	-2.2	-1.8	-2.0	-2.2	-2.0	-1.8	-2.0	-2.3	-2.2	-1.4	-1.8	-1.7	-3.2	0.2	-0.7	-2.1	-0.8	-1.1	-1.8	-1.5	-2.2	-1.8	-1.6	-1.6	-1.7	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	5.6	-0.1	0.3	-2.2	-0.6	0.1	0.4	-0.2	1.2	-0.0	-0.3	0.1	-0.2	0.7	-1.7	-2.1	0.4	-2.4	-0.2	-0.1	0.4	-0.5	-0.4	0.3	-0.0	-0.3	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.4	1.2	0.7	0.4	1.1	0.6	1.0	0.9	0.4	0.8	0.7	0.7	0.8	0.8	-0.5	0.8	0.6	-0.6	0.7	0.8	0.8	0.7	0.7	0.9	0.8	0.8	0.7
Exposure to tobacco smoke at home	0.5	0.6	1.8	1.1	0.2	0.0	1.1	0.2	0.6	0.7	1.3	0.8	0.6	0.6	0.5	0.3	-0.9	0.3	0.6	-1.3	0.2	1.0	1.3	0.5	0.6	1.0	0.8	0.4	0.6
Loud music exposure frequency	0.5	0.6	2.6	0.7	0.9	-0.9	-0.4	0.7	0.9	0.7	1.2	0.7	0.7	0.6	0.8	0.1	-1.5	-0.0	0.4	-0.7	1.6	0.2	-0.1	0.1	0.3	0.6	0.8	0.8	0.6
Medication: Amlodipine	0.5	0.7	1.8	-0.7	-0.9	-1.1	-0.9	-1.3	-1.0	-0.8	-0.4	-0.7	-0.7	-0.8	-1.0	-0.8	-0.2	-1.4	-0.7	-0.6	-0.9	-0.6	-0.2	-1.0	-0.8	-0.5	-0.6	-1.0	-0.7
Medication: Ibuprofen	0.5	0.6	1.3	1.0	0.8	0.6	1.2	0.5	0.9	1.0	0.3	0.8	0.8	0.8	0.9	0.7	-0.2	1.1	0.7	-0.5	0.7	0.9	0.8	0.9	0.8	0.8	0.9	0.9	0.8
Friendships satisfaction	0.5	0.6	2.5	-0.7	-0.4	0.9	0.1	-1.0	-0.6	-0.6	-0.6	-0.3	-0.7	-0.5	-0.7	-0.7	1.5	0.5	-1.0	1.6	-0.9	-0.6	-0.6	-0.5	-0.5	-0.8	-0.8	-0.6	-0.7
Qualifications: nursing, teaching	0.5	0.8	6.1	0.3	0.3	2.3	0.8	0.3	0.2	0.1	-0.4	0.8	-0.2	0.1	0.2	-0.4	1.6	1.5	0.2	2.5	0.0	-0.3	-1.0	0.4	0.0	-0.5	-0.3	0.2	-0.2
Breast cancer (self-reported)	0.5	0.6	2.2	-0.2	0.3	0.9	0.6	0.9	0.5	0.7	0.5	0.0	0.8	0.5	0.8	1.1	1.0	1.1	0.4	1.3	0.4	0.8	0.6	1.5	1.0	0.4	0.6	1.0	0.8
Smoking status: Current	0.5	0.8	3.7	0.4	0.5	-1.4	-0.1	0.6	0.8	0.5	0.8	0.5	0.7	0.7	0.5	0.6	-1.9	-1.9	0.7	-1.8	0.8	0.6	0.8	-0.0	0.4	0.9	0.8	0.4	0.6
Commuting to job workplace: Public transport	0.5	0.6	2.1	0.9	0.7	0.3	0.8	0.6	0.7	0.6	0.4	0.6	0.5	0.9	0.7	0.9	-0.5	0.8	0.9	-1.5	0.1	0.8	1.0	0.9	0.6	0.8	0.6	0.7	0.6
Ever smoked	0.5	0.9	6.1	1.1	1.1	-1.2	0.3	-0.2	0.6	0.5	0.9	1.1	0.1	0.5	0.2	-0.6	-2.2	-1.7	1.0	-2.5	0.4	0.4	0.4	-0.3	-0.1	0.8	0.6	-0.0	0.1
Age started oral contraceptive pill	0.5	0.6	1.6	0.6	0.7	0.9	0.9	1.3	0.7	0.7	0.8	0.5	0.7	0.9	0.8	1.2	0.2	1.1	0.6	0.2	0.3	0.9	0.8	1.1	0.9	0.7	0.7	0.7	0.7
Supplements: Calcium	0.5	0.5	3.0	0.7	0.3	0.3	0.4	0.5	0.9	0.6	1.7	0.6	0.7	0.8	0.8	1.1	-0.1	-0.0	0.4	0.2	0.6	0.8	0.7	0.8	0.7	0.6	0.7	0.9	0.7
Reaction Time	0.4	0.8	1.8	1.3	0.9	0.4	1.1	0.4	0.8	1.1	1.3	1.2	0.9	0.8	0.9	0.4	-0.5	0.7	1.2	0.6	1.1	0.7	0.5	0.7	0.8	0.8	0.9	0.8	0.9
Ovarian Cancer	0.4	0.5	3.1	0.0	-0.0	1.3	0.7	-0.6	-0.4	-0.5	-0.5	0.1	-0.6	-0.5	-0.6	-0.2	1.2	0.6	-0.3	1.8	-0.7	-0.6	-0.7	-0.7	-0.6	-0.7	-0.7	-0.7	-0.6
Crohns Disease (2012)	0.4	0.7	2.6	-0.8	-1.0	-0.7	-0.7	-0.9	-0.9	-0.8	-0.0	-0.3	-0.8	-0.9	-0.8	-1.6	0.2	-1.4	-0.9	0.4	-1.0	-0.7	-0.5	-0.8	-0.9	-0.7	-0.8	-0.9	-0.8
Schizophrenia (2014)	0.4	0.8	4.7	0.7	0.6	2.2	1.1	0.4	0.1	-0.3	0.2	0.4	-0.5	0.0	-0.5	0.9	1.5	1.9	0.2	1.8	-0.6	-0.4	-0.6	-0.6	-0.3	-0.6	-0.6	-0.5	-0.5
Average weekly fortified wine intake	0.4	0.4	1.3	0.4	1.0	1.1	0.8	0.3	0.7	0.5	0.8	0.6	0.4	0.7	0.6	-0.5	0.5	1.1	0.9	0.6	0.4	0.4	0.1	0.8	0.6	0.3	0.3	0.6	0.5
Heart attack	0.4	0.5	1.5	1.1	1.0	0.8	0.5	0.6	0.7	0.9	0.5	0.9	0.8	0.6	0.7	0.1	-0.8	0.1	0.8	-0.3	1.2	0.5	0.1	0.4	0.6	0.6	0.8	0.7	0.7
Mouth/teeth dental problems: Dentures	0.4	0.6	5.5	-0.2	-0.7	-1.6	-0.9	-0.0	-0.3	-0.2	-0.2	-0.5	-0.2	-0.3	-0.2	-0.0	-1.4	-2.3	-0.0	-2.0	-0.2	0.1	0.4	0.0	-0.2	0.3	0.2	-0.1	-0.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.8	0.8	1.2	1.7	1.5	0.7	0.7	0.6	0.8	1.3	0.5	0.9	0.6	0.5	0.7	0.7	1.0	0.8	0.0	0.7	0.5	0.7	0.6	0.5	0.3	0.4	0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.7	-0.8	-0.6	-0.1	-0.4	-0.9	-0.7	-1.0	-1.3	-0.9	-1.0	-0.9	-1.0	-0.2	0.7	-0.4	-0.7	0.9	-1.3	-0.7	-0.6	-0.8	-0.9	-0.8	-1.0	-1.1	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.6	-0.7	-0.4	0.3	-0.3	-0.7	-0.8	-0.6	-0.9	-0.7	-0.4	-0.6	-0.7	-1.3	0.8	0.4	-0.2	-0.6	-0.4	-0.5	-0.7	-0.8	-0.5	-0.7	-0.5	-0.7	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.9	-0.8	-0.7	-0.3	-0.5	-1.0	-1.0	-1.2	-0.5	-1.0	-0.9	-0.8	-1.2	-0.7	1.0	-1.2	-0.8	0.0	-1.4	-0.8	-0.4	-1.3	-0.9	-0.9	-1.1	-1.4	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	5.5	-0.7	-1.0	-1.6	-0.8	-0.3	-0.3	-0.5	0.2	-0.3	-0.3	-0.6	-0.4	-0.1	-0.7	-2.4	-0.6	-0.1	-0.4	-0.3	0.3	-0.5	-0.4	-0.1	-0.4	-0.3	-0.3
Medication: Gliclazide	0.4	0.4	1.3	0.5	0.6	-0.4	0.7	0.2	0.5	0.5	0.1	0.8	0.4	0.5	0.4	1.1	-1.1	-1.1	0.8	-0.4	-0.1	0.7	1.1	0.6	0.5	0.7	0.4	0.3	0.5
Wears glasses or contact lenses	0.4	0.4	1.9	0.7	0.5	-0.5	0.4	-0.1	0.9	0.3	1.4	0.4	0.1	0.6	0.3	0.7	-1.3	-0.5	0.6	-1.2	-0.1	0.6	0.9	0.4	0.1	0.7	0.4	0.2	0.1
Average weekly beer plus cider intake	0.4	0.6	1.7	-0.5	-0.2	0.4	-0.4	-0.6	-0.5	-0.7	-0.8	-0.3	-0.6	-0.8	-0.8	-0.9	0.8	0.5	-0.8	0.9	-0.2	-1.0	-1.2	-1.3	-0.9	-0.9	-0.8	-0.8	-0.7
Basal cell carcinoma (self-reported)	0.4	0.5	1.4	-0.7	-0.5	0.3	-0.3	-0.9	-0.3	-0.7	-0.2	-0.5	-0.9	-0.6	-0.5	-0.9	1.0	-0.6	-0.6	1.2	-0.9	-0.7	-0.9	-0.2	-0.7	-0.9	-0.9	-0.4	-0.9
Schizophrenia (2018)	0.3	0.6	4.2	0.8	0.6	1.8	1.0	0.3	0.2	-0.0	0.3	0.6	-0.3	0.1	-0.2	0.7	1.0	1.7	0.3	2.0	-0.4	-0.1	-0.2	-0.2	-0.1	-0.2	-0.3	-0.3	-0.3
Prostate Cancer	0.3	0.4	1.4	-0.5	-0.8	-0.2	-0.4	-0.3	-0.6	-0.7	-0.7	-0.4	-0.7	-0.7	-0.7	0.4	0.3	-0.9	-0.7	0.4	-1.2	-0.5	-0.2	-0.3	-0.6	-0.6	-0.9	-0.7	-0.6
Mean Putamen Volume	0.3	0.4	1.1	-0.6	0.1	0.4	0.3	-0.1	-0.0	-0.8	-0.4	-0.2	-0.7	-0.3	-0.8	0.1	1.0	0.4	0.2	-0.5	-1.1	-0.6	-0.5	-0.9	-0.7	-0.6	-0.9	-1.0	-0.7
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.5	-1.0	-0.3	-1.1	-1.2	-0.2	-0.5	-0.7	-0.3	-1.0	-0.6	-0.6	-0.6	-0.2	0.3	-0.8	-0.8	-0.3	-0.2	-0.8	-0.7	-0.8	-0.7	-0.7	-0.6	-0.6	-0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.1	0.6	0.4	-0.4	0.2	0.2	0.6	0.5	1.0	0.4	0.4	0.6	0.5	0.6	-0.9	-0.6	0.3	-0.7	0.4	0.6	0.7	0.6	0.4	0.7	0.6	0.5	0.4
Supplements: Glucosamine	0.3	0.4	1.8	-0.3	-0.2	1.0	-0.2	-0.8	-0.6	-0.3	-0.3	-0.1	-0.5	-0.3	-0.4	-1.3	1.0	-0.1	0.1	0.8	0.2	-0.6	-1.4	-0.7	-0.5	-0.8	-0.3	-0.5	-0.6
Alcohol usually taken with meals	0.3	0.5	2.3	0.3	0.3	1.2	0.3	0.5	0.5	0.6	0.6	0.2	0.9	0.5	0.8	-0.0	1.0	1.4	0.4	1.5	0.8	0.5	0.2	0.8	0.8	0.3	0.5	0.8	0.9
Qualifications: None of the above	0.3	0.7	4.0	-0.0	-0.2	-2.0	-0.8	0.5	0.3	0.4	0.5	-0.5	0.5	0.2	0.4	0.9	-1.9	-1.1	0.1	-2.0	0.4	0.5	1.0	0.6	0.4	0.8	0.6	0.6	0.5
Time employed in main current job	0.3	0.3	1.2	0.6	0.4	0.3	0.9	0.5	0.2	0.4	0.2	0.3	0.4	0.5	0.3	1.0	-0.2	0.2	1.0	-0.7	-0.3	0.7	1.1	0.6	0.5	0.6	0.3	0.2	0.5
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.2	1.0	0.7	0.0	1.0	-0.3	0.9	0.5	0.9	0.7	0.5	0.7	0.4	0.7	-0.7	-0.3	0.6	-0.9	0.0	0.7	1.1	0.5	0.5	0.8	0.5	0.4	0.5
Mean time to correctly identify matches	0.3	0.6	1.7	1.1	0.6	0.6	0.8	0.3	0.7	0.9	0.8	0.9	0.8	0.6	0.8	0.2	-0.2	1.1	0.9	1.3	1.0	0.6	0.3	0.7	0.7	0.6	0.8	0.8	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.3	-0.8	-0.4	0.4	-0.2	-0.0	-0.9	-0.6	0.3	-0.7	-0.5	-0.4	-0.6	0.4	1.1	-0.6	-0.7	1.0	-1.0	-0.4	-0.2	-0.2	-0.3	-0.6	-0.7	-0.6	-0.4
Commuting to job workplace: Walk	0.3	0.4	2.6	-0.6	-0.2	1.0	0.6	-0.2	-0.2	-0.3	-0.5	-0.4	-0.2	-0.1	-0.2	-0.5	1.6	1.6	-0.3	0.1	-0.9	-0.2	0.1	0.4	-0.0	-0.5	-0.7	-0.1	-0.2
Eye problems/disorders: Cataract	0.3	0.3	0.8	0.9	0.8	0.2	0.8	0.7	0.8	0.5	0.0	0.8	0.4	0.6	0.6	0.6	-0.4	-0.0	0.9	-0.1	0.3	0.4	0.5	0.5	0.4	0.5	0.4	0.5	0.4
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.9	0.3	0.0	-0.9	-0.3	0.1	0.7	0.5	0.5	-0.2	0.5	0.4	0.7	0.3	-1.2	0.3	0.3	-1.4	0.7	0.5	0.6	0.7	0.5	0.7	0.7	0.8	0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.8	0.5	-0.2	-1.0	0.4	0.1	-0.2	0.3	0.9	0.2	0.3	0.1	0.0	0.0	-1.3	-0.8	0.1	-1.4	-0.2	0.5	1.1	0.0	0.1	0.7	0.4	-0.0	0.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.2	-0.9	-0.5	-0.4	-0.5	-1.0	-0.5	-0.5	-1.1	-0.5	-0.6	-0.6	-0.6	-0.7	0.2	-0.5	-0.4	0.0	-0.5	-0.4	-0.3	-0.5	-0.5	-0.4	-0.4	-0.6	-0.6
Commuting to job workplace: Cycle	0.3	0.4	2.7	0.9	0.7	1.6	0.7	0.1	0.6	0.5	0.4	0.8	0.3	0.5	0.5	0.1	0.6	1.0	0.6	0.3	0.5	0.1	-0.3	0.5	0.4	0.0	0.2	0.5	0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.4	1.1	0.9	0.8	0.5	0.6	0.7	0.8	0.5	0.8	0.8	0.6	0.7	0.1	-0.7	0.2	0.7	-0.3	1.2	0.4	0.1	0.4	0.6	0.6	0.7	0.7	0.7
Fasting Glucose	0.2	0.2	1.3	0.3	0.2	-0.6	-0.1	-0.7	0.2	-0.3	0.3	0.1	0.4	0.3	0.3	-0.8	-0.8	0.3	0.1	-1.1	0.4	0.2	0.2	0.2	0.3	0.2	0.3	0.3	0.4
Rheumatoid Arthritis	0.2	0.3	2.6	-0.5	-0.5	-0.8	-0.4	0.2	0.1	-0.4	-0.2	-0.3	-0.0	0.0	-0.1	1.6	-0.3	-1.2	-0.1	-0.3	-0.7	0.3	0.9	0.3	0.1	0.2	-0.0	-0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.6	-0.1	0.6	0.7	0.6	-0.1	0.5	0.2	-0.4	0.1	0.5	0.3	0.4	0.2	0.6	0.8	0.6	-0.1	0.3	0.4	0.3	0.7	0.6	0.3	0.3	0.5	0.5
Height	0.2	4.5	14.4	2.2	1.7	1.6	3.4	1.6	2.1	1.7	0.7	1.4	1.9	2.1	1.8	3.1	-0.9	0.7	2.6	-1.6	-0.3	2.8	3.8	2.6	2.3	2.5	1.6	1.5	2.0
Systolic Blood Pressure	0.2	1.2	11.4	-0.1	-0.5	-2.1	-0.7	-0.3	-0.3	-0.2	0.7	-0.4	-0.4	-0.0	-0.4	0.3	-2.2	-2.3	-0.0	-3.4	-0.7	0.2	1.0	-0.3	-0.3	0.5	0.1	-0.5	-0.3
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.4	-0.3	-0.5	-0.3	-0.4	-0.3	-0.2	-0.4	-1.2	-0.5	-0.3	-0.5	-0.4	-0.8	-0.1	-0.2	-0.4	-0.6	-0.4	-0.3	-0.1	-0.6	-0.4	-0.3	-0.4	-0.4	-0.3
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.4	0.9	0.5	-0.2	0.3	0.5	0.2	0.3	0.6	0.9	0.1	0.3	0.1	0.2	-0.9	-1.2	0.4	0.1	0.4	0.0	-0.1	-0.2	-0.0	0.3	0.2	0.0	0.1
Serious illness, injury or assault to yourself	0.2	0.2	1.4	0.0	-0.1	-1.2	-0.2	0.1	0.1	0.0	0.4	0.0	0.1	0.2	-0.0	0.1	-1.2	0.0	0.1	-1.2	-0.1	0.3	0.8	-0.1	0.0	0.5	0.3	-0.1	0.1
Depression (self-reported)	0.2	0.2	1.0	-0.6	-0.7	-0.7	-0.9	-0.0	-0.2	-0.4	0.0	-0.7	-0.3	-0.5	-0.3	0.0	0.1	-1.0	-0.9	0.2	-0.2	-0.4	-0.3	-0.2	-0.3	-0.4	-0.3	-0.1	-0.3
Length of working week for main job	0.2	0.2	0.4	-0.4	-0.5	0.2	-0.2	-0.2	-0.1	-0.5	-0.4	-0.4	-0.4	-0.5	-0.4	0.3	0.6	-0.4	-0.2	0.3	-0.5	-0.5	-0.4	-0.5	-0.5	-0.5	-0.6	-0.5	-0.4
Hair/balding pattern: Pattern 4	0.2	0.6	3.1	-1.2	-1.1	-1.7	-1.6	-0.3	-0.6	-0.5	-0.1	-1.1	-0.4	-0.5	-0.2	0.3	-0.5	-1.8	-0.6	-0.3	-0.2	-0.4	-0.3	0.0	-0.4	-0.3	-0.3	-0.0	-0.4
Number of children fathered	0.2	0.2	1.6	-0.5	0.2	-0.5	-0.8	-0.1	0.2	0.3	0.4	-0.2	0.5	0.3	0.4	-0.7	-0.6	0.0	0.1	-0.6	1.2	0.0	-0.3	-0.0	0.3	0.2	0.5	0.5	0.5
Illnesses of father: Heart disease	0.2	0.3	1.4	0.5	0.3	-0.0	0.1	-0.2	-0.1	0.5	0.6	0.9	0.4	0.1	0.4	-1.1	-0.6	-1.2	0.5	0.3	1.0	0.2	-0.2	-0.1	0.2	0.3	0.6	0.3	0.4
Ever had bowel cancer screening	0.2	0.2	1.0	-0.3	-0.6	-0.5	-0.6	-0.5	-0.3	-0.2	0.2	-0.3	-0.5	-0.3	-0.4	-0.3	-0.1	-1.0	-0.4	-0.5	-0.1	-0.5	-0.6	-0.4	-0.5	-0.4	-0.3	-0.3	-0.5
Average weekly champagne plus white wine intake	0.2	0.2	1.7	0.5	0.4	-0.4	-0.2	0.1	0.2	0.2	0.4	0.3	0.1	0.2	-0.0	-1.0	-0.8	0.2	0.2	-1.3	0.9	-0.1	-0.4	-0.7	-0.2	0.1	0.3	-0.1	0.1
Ever taken oral contraceptive pill	0.2	0.2	1.8	-0.0	-0.3	-0.9	-0.5	-0.3	-0.1	-0.1	-0.1	-0.3	-0.2	-0.2	-0.1	-0.5	-0.6	-1.3	-0.0	-1.3	-0.1	-0.1	0.1	-0.2	-0.2	0.0	-0.1	-0.1	-0.2
Mother’s age at death	0.2	0.2	2.8	0.1	0.6	0.7	0.5	0.3	0.6	-0.0	-0.0	0.5	0.0	0.3	0.1	0.2	0.2	1.7	0.6	1.1	0.1	-0.0	-0.2	-0.2	-0.0	-0.0	-0.0	-0.1	-0.0
Financial situation satisfaction	0.2	0.3	2.2	0.1	-0.2	-1.2	-0.1	-0.1	0.1	0.0	0.4	0.4	-0.0	0.2	-0.1	0.1	-1.5	-0.1	0.1	-1.3	0.2	0.1	0.3	-0.5	-0.2	0.4	0.3	-0.2	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.2	0.5	0.8	0.8	1.1	0.7	0.5	0.5	0.7	0.9	0.1	0.5	0.4	0.3	0.3	0.2	0.6	0.2	-0.0	0.4	0.2	0.7	0.4	0.3	0.3	0.4	0.2
Coronary Artery Disease (CAD)	0.1	0.1	0.5	0.0	0.1	-0.3	-0.3	-0.6	-0.0	-0.2	0.3	0.1	-0.1	-0.1	-0.2	-0.7	0.5	-0.3	0.1	0.7	0.3	-0.3	-0.5	-0.4	-0.2	-0.2	-0.0	-0.1	-0.1
Blood Platelet Count	0.1	1.3	13.2	0.5	-0.2	-0.2	-0.8	-0.7	-0.8	-0.3	0.7	0.2	-0.6	-0.8	-0.7	-3.6	-0.3	0.1	-0.5	-0.7	1.0	-1.4	-2.3	-2.0	-1.1	-1.0	-0.4	-0.8	-0.7
Hair Pigment	0.1	1.8	4.0	-1.3	-1.2	0.3	-0.8	-1.5	-1.3	-1.3	-1.1	-1.0	-1.4	-1.5	-1.3	-1.2	2.0	-0.5	-1.3	1.3	-1.2	-1.6	-1.8	-1.1	-1.3	-1.7	-1.7	-1.2	-1.4
Medication for hormone replacement therapy	0.1	0.1	0.6	0.4	0.3	0.6	0.4	-0.0	0.3	0.1	-0.4	0.5	-0.2	-0.0	-0.0	0.0	0.2	-0.2	0.4	0.8	0.1	-0.2	-0.3	-0.3	-0.2	-0.1	-0.1	-0.1	-0.2
Maternal smoking around birth	0.1	0.2	1.3	-0.5	0.4	-0.8	-0.4	-0.3	0.4	-0.1	0.3	-0.1	0.2	-0.0	0.1	-0.5	-0.6	-1.1	0.1	-0.9	0.2	0.0	0.1	-0.2	0.0	0.1	0.1	0.1	0.1
Multivitamins +/- minerals	0.1	0.1	1.5	0.3	0.1	-0.2	0.1	-0.3	0.3	-0.0	0.4	0.2	0.1	0.3	0.0	0.1	-0.4	-0.7	0.6	-1.2	0.1	0.1	0.1	-0.3	-0.0	0.2	0.2	-0.1	0.1
Stomach or abdominal pain in last month	0.1	0.1	0.7	0.0	-0.2	-0.1	-0.2	0.2	-0.3	-0.1	0.1	0.2	-0.4	-0.3	-0.3	-0.4	0.1	-0.4	-0.4	0.3	0.3	-0.5	-0.8	-0.8	-0.5	-0.4	-0.2	-0.3	-0.4
Medication: Levothyroxine sodium	0.1	0.2	0.8	-0.4	-0.4	-0.1	0.0	-0.4	-0.3	-0.6	-0.9	-0.4	-0.4	-0.5	-0.6	0.1	0.3	-0.4	-0.3	0.5	-0.8	-0.3	-0.0	-0.6	-0.4	-0.3	-0.5	-0.7	-0.4
Hair/balding pattern: Pattern 2	0.1	0.2	1.2	-0.3	0.5	0.5	0.3	0.7	0.1	-0.1	-0.2	0.4	0.0	0.1	-0.1	0.2	1.0	1.1	-0.1	0.7	0.0	-0.2	-0.4	-0.2	-0.0	-0.3	-0.2	-0.1	0.0
Standing height	0.1	0.7	4.4	0.4	0.5	1.6	2.1	0.2	0.5	0.1	-0.9	0.4	0.3	0.5	0.2	0.8	1.1	1.0	0.8	0.2	-1.3	0.9	1.5	0.9	0.6	0.5	-0.0	0.0	0.4
Eye problems/disorders: None of the above	0.1	0.1	0.9	0.2	0.1	-0.3	-0.1	0.2	0.0	0.0	0.9	0.1	-0.1	0.3	-0.1	0.5	-0.7	-0.3	0.0	-0.9	0.0	0.1	0.1	-0.2	-0.1	0.2	0.2	-0.1	-0.1
Migraine (self-reported)	0.1	0.1	1.0	0.3	0.3	-0.8	-0.3	-0.1	0.1	0.0	0.6	0.4	0.1	-0.0	-0.0	-0.1	-1.0	-0.5	0.1	-0.4	0.3	-0.0	0.1	-0.3	-0.1	0.2	0.1	-0.0	0.1
Medication: Omeprazole	0.1	0.1	0.6	0.2	0.3	0.5	0.8	0.2	0.1	-0.1	0.1	0.4	-0.4	-0.0	-0.2	0.0	0.2	-0.2	0.2	-0.4	-0.8	-0.1	0.1	0.0	-0.2	-0.1	-0.4	-0.3	-0.4
Comparative height size at age 10	0.1	0.5	4.7	0.6	0.4	0.3	1.0	0.0	0.4	0.3	-0.0	0.6	0.4	0.4	0.3	0.1	-0.5	-2.2	1.2	-0.4	-0.2	0.8	1.1	0.3	0.5	0.7	0.5	0.1	0.5
Supplements: Vitamin C	0.1	0.2	0.6	0.1	-0.2	0.2	-0.2	-0.2	-0.3	-0.5	-0.8	-0.1	-0.4	-0.4	-0.5	-0.5	0.3	-0.3	-0.0	0.2	-0.5	-0.4	-0.4	-0.6	-0.5	-0.4	-0.5	-0.6	-0.4
Average weekly red wine intake	0.1	0.2	2.0	-0.3	-0.3	0.3	-0.6	-0.2	-0.2	-0.1	-0.5	-0.3	0.1	-0.2	0.0	-0.4	0.9	0.3	-0.6	1.4	0.4	-0.3	-0.7	-0.0	0.0	-0.4	-0.1	0.2	0.0
Mineral and other dietary supplements	0.1	0.2	0.8	0.5	-0.0	-0.6	0.0	0.3	0.2	0.3	0.3	0.1	0.4	0.2	0.4	0.8	-0.8	0.1	-0.0	-0.3	-0.0	0.5	0.9	0.6	0.4	0.6	0.3	0.4	0.4
Osteoarthritis (self-reported)	0.1	0.1	0.6	0.3	0.3	0.5	0.8	0.4	0.1	0.2	-0.0	0.4	0.1	0.2	0.1	0.1	-0.1	0.3	0.7	-0.1	-0.4	0.5	0.7	0.2	0.2	0.4	0.2	-0.0	0.1
Alcohol drinker status: Never	0.1	0.2	0.6	-0.3	-0.5	-0.6	-0.2	0.3	-0.3	0.2	-0.2	-0.5	0.6	0.1	0.2	0.1	0.1	0.4	-0.3	-0.7	0.1	0.4	0.8	0.5	0.5	0.3	0.3	0.3	0.6
Tanning	0.0	0.6	4.0	0.1	0.5	1.6	0.6	0.9	0.2	0.1	-0.4	0.2	0.2	0.1	0.1	0.2	1.8	2.0	-0.4	1.7	0.3	-0.1	-0.7	0.0	0.2	-0.4	-0.1	0.1	0.1
Severe depression (siblings)	0.0	0.0	0.2	-0.1	0.1	0.1	0.2	0.5	-0.3	-0.0	0.3	0.1	-0.0	-0.0	-0.1	0.3	0.5	-0.0	0.1	0.1	-0.2	0.1	0.1	0.1	0.1	-0.0	0.0	-0.1	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.2	-0.5	0.2	-0.0	-0.1	0.1	-0.1	-0.2	0.2	-0.2	-0.2	0.2	-0.1	0.3	0.2	0.1	0.2	0.0	-0.2	0.0	0.0	-0.1	-0.1	-0.1	-0.0	-0.2	-0.1