Hub : Genes

STX4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0630	0.0300	1.9e-03	0.048	NA	-0.002	NA	0.020	7.7e-05	NA	5.0e-01	NA	7.8e-03
2	GTEx	Brain Cerebellum	0.1370	0.0580	2.4e-04	0.247	NA	0.161	NA	0.243	6.5e-08	NA	1.8e-05	NA	8.3e-08
3	GTEx	Brain Nucleus accumbens basal ganglia	0.1910	0.0900	3.8e-03	0.108	NA	0.087	NA	0.062	8.0e-04	NA	2.6e-03	NA	9.7e-03
4	GTEx	Colon Transverse	0.1020	0.0560	4.5e-03	0.095	NA	0.045	NA	0.062	2.9e-05	NA	3.3e-03	NA	6.6e-04
5	GTEx	Esophagus Gastroesophageal Junction	0.0910	0.0510	6.1e-03	0.003	NA	-0.008	NA	-0.008	2.5e-01	NA	9.9e-01	NA	9.8e-01
6	GTEx	Esophagus Mucosa	0.0840	0.0360	2.5e-04	0.000	NA	0.023	NA	0.022	2.9e-01	NA	1.0e-02	NA	1.3e-02
7	GTEx	Esophagus Muscularis	0.0460	0.0270	9.1e-03	0.054	NA	0.005	NA	0.029	3.5e-04	NA	1.5e-01	NA	6.7e-03
8	GTEx	Muscle Skeletal	0.0428	0.0217	4.3e-04	0.036	NA	0.023	NA	0.033	1.7e-04	NA	2.5e-03	NA	2.9e-04
9	GTEx	Nerve Tibial	0.0652	0.0293	1.8e-04	0.041	NA	0.039	NA	0.022	6.4e-04	NA	9.4e-04	NA	9.8e-03
10	GTEx	Ovary	0.1580	0.0870	7.7e-03	0.048	NA	0.069	NA	0.040	2.6e-02	NA	9.0e-03	NA	3.8e-02
11	GTEx	Skin Sun Exposed Lower leg	0.0370	0.0190	1.5e-03	0.021	NA	0.038	NA	0.023	7.3e-03	NA	3.9e-04	NA	5.2e-03
12	GTEx	Testis	0.1550	0.0780	2.3e-03	0.019	NA	0.011	NA	0.013	4.9e-02	NA	1.0e-01	NA	8.2e-02
13	GTEx	Thyroid	0.0630	0.0280	6.0e-04	0.023	NA	0.032	NA	0.033	6.4e-03	NA	1.7e-03	NA	1.4e-03
14	ROSMAP	Brain Pre-frontal Cortex	0.0642	0.0211	4.5e-12	0.114	0.101	0.102	0.099	0.107	1.8e-14	6.7e-13	5.4e-13	9.9e-13	1.4e-13
15	YFS	Blood	0.0262	0.0091	4.4e-14	0.056	0.046	0.051	0.051	0.054	1.0e-17	5.8e-15	3.2e-16	3.4e-16	4.3e-17

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	1.1	1.8	7.6	1.3	1.0	-0.6	1.2	2.8	0.4	1.1	1.0	2.0	0.9	1.1	1.3	1.6	-1.0	1.1
Bipolar Disorder or Schizophrenia	0.6	1.5	4.3	1.6	0.8	-0.3	1.1	2.1	-0.1	1.0	1.1	1.6	0.3	1.1	1.5	2.0	-0.8	1.2
Depressed Affect (Nagel 2018)	7.4	15.6	23.5	-0.7	-4.3	4.0	-4.4	-1.7	-4.1	-4.6	-4.8	-3.4	-3.5	-2.8	-4.5	-4.7	4.3	-4.8
Depression (Nagel 2018)	1.1	1.6	3.8	-0.8	-1.4	0.8	-1.7	0.2	-0.3	-1.6	-1.6	-0.9	-1.1	-1.0	-1.6	-1.9	1.2	-1.3
Intelligence (Savage-Jansen 2018)	1.1	3.5	6.5	-0.1	2.1	-1.3	2.0	2.0	2.5	1.9	1.7	2.1	0.6	2.0	2.4	2.2	-1.9	1.8
Neuroticism (Nagel 2018)	12.2	28.6	40.3	-1.7	-6.2	5.5	-6.0	-2.9	-5.5	-6.2	-6.3	-4.8	-5.0	-3.8	-5.9	-5.4	6.2	-6.3
Schizophrenia (2018)	0.2	0.4	1.6	1.0	0.3	0.0	0.5	0.4	-0.5	0.4	0.6	0.5	-0.3	0.5	0.8	1.3	-0.2	0.7
Schizophrenia vs Biploar Disorder	0.4	0.5	1.1	-0.6	-1.1	0.4	-0.9	-0.7	-0.2	-0.8	-0.7	-1.0	-0.5	-0.5	-0.8	-0.6	1.0	-0.7
Worry (Nagel 2018)	9.6	20.3	31.1	-2.4	-5.3	4.0	-5.3	-2.6	-4.0	-5.4	-5.6	-3.8	-4.4	-3.1	-4.7	-4.1	5.4	-5.6
Alzheimer’s Disease (in mother)	4.3	5.1	7.7	-2.3	-2.6	1.7	-2.7	-0.9	-1.4	-2.7	-2.8	-2.1	-2.6	-2.2	-2.4	-0.5	2.6	-2.8
Alzheimer’s Disease (in father)	3.4	3.7	5.2	-2.2	-2.0	2.3	-2.2	-0.6	-1.1	-2.1	-2.1	-1.5	-2.3	-1.9	-2.2	-1.1	2.2	-2.1
Alzheimer’s Disease (including proxy)	10.0	14.5	21.2	-4.0	-3.9	3.6	-4.2	-1.5	-2.9	-4.3	-4.6	-3.6	-4.5	-4.2	-4.0	-1.7	4.0	-4.4
Crohns Disease (2017)	2.6	5.7	11.8	-2.7	-2.4	2.1	-2.1	0.5	-1.9	-2.2	-2.3	-2.6	-3.1	-3.4	-2.1	-2.9	2.1	-2.3
Irritable Bowel Disease (IBD)	1.9	4.6	8.6	-2.3	-2.5	2.1	-1.9	0.1	-1.8	-1.9	-1.9	-2.2	-2.4	-2.6	-2.0	-2.9	2.4	-1.9
Ulcerative Colitis (UC)	0.5	1.0	2.2	-1.3	-1.3	1.3	-0.7	0.1	-0.8	-0.7	-0.6	-0.9	-0.9	-0.7	-0.9	-1.4	1.5	-0.5
Major Depression (MDD)	1.2	1.4	2.4	-0.7	-1.6	1.4	-1.5	-0.2	-0.9	-1.2	-1.5	-1.0	-1.3	-0.8	-1.4	-1.0	1.4	-1.1
Reaction Time	0.6	1.1	3.4	-0.2	1.1	-1.2	1.3	-1.8	0.7	1.4	1.3	0.7	-0.1	0.3	0.8	0.9	-1.0	1.4
Verbal and Numeric Reasoning (VNR)	1.9	4.5	8.8	-0.5	2.3	-2.0	2.5	1.5	3.0	2.2	1.9	2.7	1.1	2.3	2.8	1.6	-2.2	2.0
Breast Cancer	1.8	4.3	6.9	-0.2	2.2	-2.3	2.2	1.2	2.6	2.5	2.6	2.2	1.6	1.8	2.3	1.1	-2.1	2.6
Ovarian Cancer	0.2	0.3	1.4	-0.7	-0.3	0.9	-0.1	-1.2	-0.6	-0.1	-0.2	-0.2	-0.3	0.3	-0.4	0.8	0.6	0.0
Prostate Cancer	0.4	0.6	1.5	1.2	-0.7	0.8	-0.7	-1.0	-1.1	-0.7	-0.5	-0.6	-0.3	0.4	-0.8	-0.6	0.8	-0.5
Age at First Birth	0.6	0.9	1.8	0.1	-1.3	1.2	-1.0	-0.6	-1.3	-0.9	-0.8	-0.7	-0.5	-0.2	-1.3	0.0	1.4	-0.8
Bipolar Disorder (2011)	0.5	0.4	3.2	0.9	-0.3	0.0	-0.0	1.4	0.4	-0.0	-0.0	0.4	-0.1	0.1	-0.2	1.8	0.3	-0.1
Body Mass Index (BMI) (2010)	2.0	2.7	5.2	-0.3	1.8	-1.6	2.0	0.8	1.3	2.1	2.2	1.3	1.4	0.5	2.3	0.8	-1.9	2.2
Coronary Artery Disease (CAD)	0.2	0.3	2.5	-1.6	0.3	0.1	0.0	0.7	0.5	-0.1	-0.4	0.0	-0.6	-0.1	0.2	-0.0	-0.1	-0.1
Crohns Disease (2012)	1.0	1.6	6.6	-2.6	-1.0	0.7	-0.6	0.6	-0.1	-0.8	-1.0	-1.2	-2.0	-2.3	-0.5	-0.9	0.7	-1.0
Mean Putamen Volume	0.4	0.5	1.3	0.2	-0.1	1.1	-0.4	0.6	-1.1	-0.7	-0.9	-0.6	-0.8	-0.9	-0.3	0.0	0.1	-0.9
Fasting Glucose	0.2	0.2	1.8	-1.3	0.2	0.1	0.0	0.1	0.6	-0.3	0.2	0.5	0.4	0.5	0.3	-0.2	0.1	0.2
HbA1C	1.7	1.8	4.3	2.0	0.8	-1.6	0.8	1.2	1.6	0.9	0.7	2.1	2.0	1.7	0.9	1.2	-0.9	0.6
HDL Cholesterol	1.4	2.3	4.4	-0.5	-1.9	2.1	-1.8	-0.3	-1.4	-1.9	-2.0	-1.1	-1.3	-0.7	-1.3	-0.4	1.9	-2.0
LDL Cholesterol	0.7	1.0	2.2	-0.5	0.8	-1.5	1.1	-0.1	1.3	1.2	1.3	1.2	0.8	1.3	0.6	-0.3	-0.7	1.3
Lupus	1.1	1.7	6.0	1.9	0.4	-0.9	0.4	2.1	-1.6	0.1	0.3	1.2	2.4	1.9	0.6	1.2	-0.6	0.2
Neuroticism (2016)	4.9	7.0	11.3	-1.0	-3.4	2.8	-3.1	-1.5	-2.7	-2.9	-3.3	-1.9	-2.3	-2.1	-2.7	-2.6	3.4	-2.7
Primary Biliary Cirrhosis	2.4	3.4	9.1	2.4	1.6	-1.7	1.8	1.4	1.0	1.5	1.4	2.3	3.0	2.3	2.0	0.8	-1.7	1.4
Rheumatoid Arthritis	0.8	1.1	8.7	3.0	-0.4	1.0	-0.5	-0.3	-1.1	-0.7	-0.6	0.5	1.3	0.5	-0.8	-0.7	0.5	-0.7
Schizophrenia (2014)	0.2	0.5	2.0	0.9	0.1	0.6	0.4	0.9	-0.8	0.4	0.5	0.5	-0.1	0.7	0.9	1.4	-0.0	0.6
Triglycerides	7.2	11.7	16.0	3.0	3.6	-3.6	3.9	1.3	3.2	3.9	3.9	3.9	4.0	3.4	3.0	1.3	-3.7	4.0
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.7	0.5	0.3	-0.2	-0.0	0.2	-0.3	-0.1	-0.1	-0.3	0.1	-0.8	-0.5	0.6	-0.4	-0.1
Ulcerative Colitis	0.6	0.9	3.9	-2.0	-1.0	0.7	-0.3	-1.5	-0.0	-0.3	-0.4	-0.5	-0.7	-0.8	-0.7	-1.3	1.1	-0.4
Blood Eosinophil Count	0.7	5.0	29.2	-5.4	-0.1	0.6	-0.1	2.7	1.7	-0.4	-0.9	-1.7	-3.9	-2.2	-0.3	3.2	0.5	-0.7
Blood Platelet Count	0.4	4.2	31.2	-5.6	-0.1	-0.7	0.4	2.3	1.9	0.5	0.3	-0.2	-4.1	-1.3	1.6	-0.2	-0.2	0.5
Blood Red Count	11.2	107.8	141.6	-6.0	-11.4	11.5	-11.3	-5.7	-10.4	-11.1	-10.8	-10.3	-11.0	-8.9	-11.7	-10.4	11.9	-10.8
Blood White Count	1.7	12.8	50.6	-5.6	-3.0	2.5	-2.6	-1.6	-1.9	-2.5	-2.7	-4.6	-7.1	-4.8	-2.5	-0.5	3.2	-2.5
Heel T-Score	2.0	16.1	29.8	-5.5	-4.2	3.8	-4.5	-0.7	-2.2	-4.2	-4.1	-4.5	-5.3	-5.2	-3.3	-1.0	4.1	-4.0
BMI	4.9	28.5	41.2	4.1	6.3	-4.9	6.2	1.1	4.2	6.1	6.0	5.9	6.2	5.1	6.2	0.8	-6.4	5.9
Height	0.2	4.5	21.2	4.6	1.9	-0.5	1.9	-0.5	-1.6	1.9	2.3	0.3	2.8	2.2	1.2	2.0	-2.0	2.1
Waist Hip Ratio (WHR)	0.6	2.6	11.8	0.7	-1.2	2.5	-1.0	-0.9	-3.4	-1.2	-1.3	-2.2	-0.9	-0.9	-1.8	0.0	1.6	-1.4
Systolic Blood Pressure	0.1	0.4	1.9	1.1	-0.2	1.0	0.1	-0.7	-0.8	-0.0	-0.2	0.2	-0.4	0.4	0.3	-1.4	0.0	-0.2
Smoking Status	1.5	3.6	7.6	-1.0	2.7	-1.3	2.3	2.0	2.1	2.3	2.0	1.0	-0.0	0.8	2.4	0.4	-2.8	2.2
Allergy or Eczema	0.4	1.1	6.4	-0.1	0.6	-0.6	0.6	1.6	1.0	0.4	0.4	1.4	0.6	0.9	1.1	2.5	-0.5	0.4
Cardiovascular Disease	6.3	20.9	29.4	3.4	5.4	-4.2	5.4	2.3	4.0	5.3	5.1	4.9	4.5	4.5	5.3	2.0	-5.4	5.1
Hypothyroidism (self reported)	1.2	2.7	6.1	0.6	-1.5	2.2	-1.5	-1.5	-2.5	-1.7	-1.7	-2.1	-1.1	-1.1	-1.9	-1.2	1.7	-1.7
Respiratory disease	3.7	8.2	12.7	3.2	2.9	-3.0	2.9	0.2	2.9	2.9	2.9	2.9	3.6	3.4	2.5	2.3	-2.9	2.8
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.7	2.2	1.4	-0.6	1.5	-0.6	0.1	1.5	1.6	0.9	1.1	0.9	0.6	-0.3	-1.3	1.6
Lung FEV1/FVC ratio	1.7	8.8	21.1	-4.6	-3.1	3.3	-2.8	0.9	-1.9	-2.9	-3.2	-2.7	-4.5	-1.9	-2.0	-1.7	3.3	-3.1
Lung FVC	9.0	45.7	61.8	-2.2	-7.9	7.2	-7.8	-4.1	-7.4	-7.8	-7.5	-6.2	-5.7	-5.6	-7.7	-6.0	7.8	-7.6
Neuroticism	10.0	24.2	33.8	-1.8	-5.8	5.1	-5.7	-2.3	-5.5	-5.8	-5.7	-4.4	-4.5	-3.1	-5.2	-5.0	5.8	-5.8
Chronotype (morning person)	0.7	1.6	6.2	0.4	-1.2	1.6	-1.2	-2.5	-1.4	-1.1	-1.0	-0.7	-0.5	-0.1	-1.4	-1.8	1.3	-1.0
Hair Pigment	0.1	1.7	4.7	-0.6	-1.4	0.6	-1.3	-0.6	-0.9	-1.3	-1.3	-1.8	-1.5	-2.2	-1.6	-0.5	1.4	-1.3
Tanning	0.0	0.2	1.1	0.1	0.2	-0.3	0.0	0.3	0.1	-0.0	-0.2	0.9	-0.2	0.6	0.7	1.1	-0.2	-0.2
Hand grip strength (left)	4.2	11.1	21.2	3.8	3.4	-2.3	3.2	1.1	2.8	3.5	3.6	3.9	3.8	4.6	3.5	1.7	-3.4	3.6
Number of treatments/medications taken	6.3	11.4	17.3	2.7	3.6	-3.1	4.0	1.9	2.5	3.8	3.7	3.6	4.2	3.3	3.6	3.0	-3.3	3.7
Average weekly spirits intake	0.6	0.7	4.1	0.7	0.7	-0.9	0.6	2.0	1.3	0.5	0.5	1.0	0.7	0.1	0.5	0.4	-0.8	0.4
Sensitivity / hurt feelings	3.6	6.1	8.9	-1.2	-2.8	2.8	-2.7	-2.7	-3.0	-2.6	-2.5	-2.7	-2.0	-1.8	-2.3	-2.2	2.7	-2.6
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.8	0.0	-0.7	0.8	-0.9	1.3	-0.0	-1.1	-1.1	-0.4	-0.8	0.1	-1.0	-1.1	0.5	-1.1
Hearing difficulty/problems: Yes	5.2	7.9	17.0	0.8	2.9	-3.4	2.7	3.3	4.1	2.7	2.5	3.2	2.7	2.1	2.6	2.4	-3.0	2.6
Relative age of first facial hair	2.0	4.1	6.7	2.1	2.6	-1.5	2.2	0.6	1.0	2.2	2.3	2.2	2.0	2.0	1.9	1.6	-2.5	2.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.0	0.9	0.9	-0.6	0.7	0.5	0.7	0.6	0.5	0.4	1.0	0.0	0.4	0.4	-0.9	0.5
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.4	-1.2	-0.5	0.8	-0.2	-1.1	-1.1	-0.5	-0.6	-0.7	0.0	-0.4	-0.5	-0.5	0.6	-0.6
Ever had hysterectomy (womb removed)	1.4	1.6	2.4	0.6	1.2	-1.4	1.5	0.2	1.5	1.5	1.5	1.4	1.3	1.3	1.2	0.2	-1.4	1.5
Systolic blood pressure, automated reading	0.2	0.5	3.0	0.5	0.1	0.2	0.4	-1.1	-0.4	0.4	0.2	0.8	0.4	0.8	0.6	-1.7	-0.2	0.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	0.2	0.5	-0.5	0.8	0.1	0.6	0.9	0.8	-0.0	-0.6	-0.1	0.5	0.2	-0.6	0.9
Angina	0.7	0.9	3.1	-0.8	-1.0	1.6	-0.6	0.0	-0.8	-0.6	-0.6	-1.0	-0.9	-1.2	-0.8	-1.8	0.8	-0.6
Medication for hormone replacement therapy	0.1	0.2	0.5	-0.7	0.3	0.0	0.5	0.7	0.2	0.3	0.1	-0.3	-0.1	-0.5	0.3	0.5	-0.3	0.2
Vitamin and mineral supplements	0.3	0.4	1.3	-0.9	-0.8	0.9	-0.6	-0.1	-0.6	-0.4	-0.4	-0.2	-0.7	0.4	-0.5	0.0	1.1	-0.5
Supplements: Zinc	0.8	0.9	2.7	-1.0	-0.9	1.6	-0.8	-0.9	-1.6	-0.6	-0.6	-0.8	-0.9	-1.0	-0.6	-0.8	1.0	-0.5
Medication: Co-codamol	1.7	2.0	3.2	1.1	1.7	-1.7	1.6	0.7	0.9	1.6	1.6	1.5	1.8	0.9	1.4	-0.0	-1.7	1.6
Medication: Metformin	1.3	1.8	3.2	1.8	1.6	-0.6	1.4	0.7	0.8	1.5	1.6	1.4	1.3	1.8	0.9	0.9	-1.4	1.6
Diabetes (father)	0.2	0.3	0.9	0.5	-0.9	0.5	-0.5	-0.1	-0.6	-0.5	-0.5	-0.3	-0.4	-0.1	-0.7	0.1	0.9	-0.5
Diabetes (mother)	0.3	0.4	0.9	0.1	0.8	-0.8	0.8	0.2	0.2	0.8	0.9	0.7	0.8	0.2	0.3	-0.5	-0.9	0.9
Severe depression (siblings)	0.2	0.3	2.4	1.0	0.0	0.3	0.0	-1.5	-0.6	0.0	-0.0	-0.1	0.3	0.3	-0.1	0.1	0.1	-0.1
Pack years adult smoking proportion	1.9	2.9	7.0	0.7	1.7	-2.6	1.8	1.6	2.1	1.7	1.6	1.4	1.7	1.4	1.8	1.2	-2.0	1.6
Impedance of leg (right)	0.7	3.6	10.1	-2.6	-1.7	1.2	-1.2	0.3	-1.3	-1.0	-1.0	-2.2	-2.9	-3.2	-1.9	2.5	1.8	-0.9
Leg fat-free mass (left)	2.0	10.7	19.5	4.2	3.8	-2.6	3.5	0.8	1.9	3.3	3.4	3.0	4.4	3.9	3.7	-0.2	-4.0	3.2
Trunk fat percentage	6.7	26.9	40.8	4.2	6.2	-4.7	6.4	1.5	3.7	6.3	6.3	5.0	5.3	4.5	5.6	2.7	-6.1	6.3
Hand grip strength (right)	2.9	7.8	15.6	3.9	2.8	-1.9	2.6	1.0	2.4	2.7	2.8	3.1	3.4	3.8	2.9	1.4	-2.9	2.7
Townsend deprivation index at recruitment	4.2	5.8	9.9	1.5	2.8	-2.1	3.0	2.0	2.1	2.8	2.8	2.3	2.1	1.9	3.1	1.1	-2.8	2.9
Current tobacco smoking	0.4	0.6	1.8	0.4	1.2	-0.6	1.1	-0.0	1.1	0.9	0.7	0.2	0.3	0.4	0.7	-0.3	-1.3	0.7
Average weekly fortified wine intake	0.4	0.4	1.3	-0.4	0.8	-1.1	0.5	0.2	0.7	0.5	0.4	0.5	0.1	-0.5	0.8	1.0	-0.9	0.3
Maternal smoking around birth	0.2	0.3	1.6	-0.7	0.1	-0.4	-0.1	1.3	0.6	-0.4	-0.7	-0.6	-0.7	-0.5	-0.1	-0.4	-0.3	-0.7
Fed-up feelings	3.7	6.7	10.2	0.5	-2.8	3.2	-2.9	-0.8	-3.2	-3.0	-2.9	-2.4	-2.0	-1.4	-2.9	-3.1	2.7	-3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	4.1	-1.4	-0.9	1.0	-0.8	-0.8	-0.5	-0.8	-0.9	-0.9	-1.1	-0.6	-1.0	-2.0	0.9	-0.8
Relative age voice broke	5.4	8.2	11.6	2.1	3.4	-2.8	3.0	2.9	2.6	3.0	2.9	2.9	2.2	2.4	2.7	3.3	-3.4	2.9
Taking other prescription medications	1.3	2.0	5.2	1.0	1.2	-1.3	1.6	1.8	1.6	1.4	1.4	1.2	2.3	1.2	1.0	1.2	-1.1	1.4
Age when periods started (menarche)	0.4	0.9	6.9	2.6	-0.3	0.6	-0.2	-0.1	-1.0	-0.3	-0.2	0.5	0.4	1.6	-0.2	1.4	0.3	-0.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.6	0.4	0.4	-0.5	0.6	-0.3	0.5	0.5	0.5	0.2	0.8	0.6	0.5	0.0	-0.5	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	4.1	-1.8	-1.3	1.0	-1.5	-0.4	-0.4	-1.3	-1.1	-1.5	-1.9	-2.0	-1.0	-0.6	1.0	-1.1
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	5.4	2.3	1.3	-1.3	0.9	0.6	1.0	1.0	1.2	2.0	1.9	2.0	1.5	1.2	-1.3	1.1
Qualifications: CSEs or equivalent	0.2	0.2	0.8	0.9	0.2	0.4	0.3	0.5	-0.8	0.3	0.5	0.1	0.4	0.1	0.4	-0.5	-0.4	0.5
Serious illness, injury or assault to yourself	0.2	0.2	0.8	0.2	0.1	0.8	0.2	0.4	-0.6	0.0	-0.1	0.6	0.3	0.9	0.1	-0.6	-0.1	-0.1
High blood pressure	3.5	9.8	14.9	3.1	3.6	-2.6	3.8	0.8	2.0	3.7	3.5	3.3	3.9	3.0	3.4	0.9	-3.7	3.4
Hayfever, allergic rhinitis or eczema	0.2	0.4	3.5	0.4	0.1	0.1	0.1	1.2	0.1	-0.0	-0.0	0.7	0.1	0.1	0.6	1.9	0.0	-0.0
Multivitamins +/- minerals	0.1	0.1	0.5	0.1	0.3	-0.2	0.2	-0.1	0.1	0.1	0.1	0.0	-0.3	-0.4	0.5	-0.0	-0.7	0.1
Stomach or abdominal pain in last month	0.1	0.2	1.5	-1.2	-0.2	0.4	0.2	-0.1	0.3	0.1	-0.2	-0.2	-0.8	-0.2	0.1	-0.1	0.2	-0.0
Supplements: Glucosamine	0.4	0.5	3.5	-1.9	-0.1	-0.1	-0.2	-0.8	0.3	-0.1	-0.0	-0.4	-0.9	-1.4	0.2	0.4	-0.1	0.0
Diverticular disease/diverticulitis (self-reported)	3.5	4.1	7.0	-1.3	-2.1	2.5	-1.9	-0.5	-2.7	-2.0	-2.0	-1.9	-1.6	-2.4	-2.1	-2.3	2.0	-2.1
Medication: Atenolol	0.3	0.4	1.8	0.1	-0.3	0.7	-0.7	-0.3	-0.8	-0.7	-0.8	-0.7	-0.4	-0.3	-0.5	-1.3	0.4	-0.8
Medication: Levothyroxine sodium	0.3	0.5	1.8	1.2	-0.3	1.3	-0.4	-0.0	-1.4	-0.5	-0.5	-0.7	-0.0	0.3	-0.8	-0.2	0.6	-0.5
Sitting height	0.6	4.3	9.2	-3.0	-1.7	1.2	-2.1	0.2	-1.1	-2.3	-2.4	-2.2	-2.9	-2.0	-1.8	-2.2	1.5	-2.3
Chronic bronchitis/emphysema (father)	6.4	7.5	10.9	-0.1	3.1	-2.8	3.3	2.2	2.9	3.0	2.8	2.9	2.3	2.7	3.1	2.3	-3.1	2.9
High blood pressure (mother)	0.2	0.3	0.8	-0.8	0.6	-0.3	0.5	-0.9	-0.4	0.5	0.5	0.0	-0.2	-0.2	0.5	-0.7	-0.7	0.4
Body mass index (BMI)	5.9	25.0	34.6	4.1	5.8	-4.6	5.8	1.3	4.2	5.7	5.7	5.3	5.8	5.1	5.5	0.5	-5.9	5.6
Impedance of leg (left)	0.7	3.4	8.1	-2.1	-1.7	1.5	-1.3	-0.3	-1.7	-1.2	-1.2	-2.1	-2.8	-2.8	-2.0	2.1	1.9	-1.1
Leg predicted mass (left)	2.0	10.8	19.0	4.1	3.8	-2.6	3.5	0.9	1.9	3.3	3.4	3.1	4.4	4.0	3.7	-0.2	-4.0	3.2
Trunk fat mass	6.2	26.6	39.7	4.5	6.3	-4.6	6.3	1.3	3.5	6.2	6.1	4.8	5.6	4.7	5.6	2.2	-6.2	6.1
Waist circumference	8.4	30.7	45.4	4.7	6.6	-4.8	6.7	1.9	3.6	6.5	6.3	5.8	6.5	5.6	6.0	1.9	-6.5	6.3
Number of incorrect matches in round	6.5	10.9	15.3	-1.9	-3.8	3.2	-3.7	-3.7	-3.3	-3.7	-3.7	-3.3	-3.2	-2.6	-3.2	-0.7	3.9	-3.7
Past tobacco smoking	1.4	2.6	5.1	2.3	-2.1	0.6	-1.9	-1.9	-1.7	-2.0	-1.8	-0.6	0.5	-0.1	-1.9	-0.5	2.1	-1.9
Alcohol usually taken with meals	0.2	0.3	1.1	-0.2	0.3	-1.0	0.1	0.3	0.7	0.2	0.3	0.1	0.4	-0.8	0.6	0.9	-0.4	0.3
Nervous feelings	7.0	13.1	20.7	-2.9	-4.4	3.1	-4.0	-1.8	-2.6	-4.3	-4.5	-2.8	-4.0	-3.0	-3.8	-2.7	4.4	-4.5
Frequency of tenseness / restlessness in last 2 weeks	5.7	8.9	16.3	-2.7	-3.0	3.0	-3.0	-1.7	-2.3	-3.2	-3.3	-3.2	-4.0	-2.3	-3.0	-3.2	2.9	-3.3
Hearing difficulty/problems with background noise	1.4	2.3	3.8	0.8	1.8	-2.0	1.6	1.4	1.9	1.3	1.2	1.6	1.6	1.0	1.5	1.8	-1.8	1.2
Hair/balding pattern: Pattern 2	0.2	0.2	1.6	0.5	0.1	-0.3	0.1	1.3	0.1	-0.1	-0.4	0.4	-0.3	0.6	0.4	0.3	-0.1	-0.4
Had menopause	2.3	2.9	5.0	0.6	1.8	-1.4	2.2	0.6	1.3	2.1	2.0	2.1	2.2	1.0	1.5	1.7	-1.7	2.0
Had other major operations	0.7	0.9	1.9	0.6	1.3	0.2	1.3	0.9	0.1	1.1	1.0	0.6	1.3	0.8	0.8	0.0	-1.4	0.9
Forced vital capacity (FVC)	7.5	29.1	47.6	-0.7	-6.0	6.3	-6.2	-3.1	-6.9	-6.1	-5.8	-5.7	-4.3	-3.6	-6.1	-4.6	6.0	-6.0
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	5.5	-1.7	-2.0	2.0	-2.1	-0.2	-1.3	-2.1	-1.9	-2.2	-2.3	-2.1	-1.6	-0.7	1.7	-1.9
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	2.9	0.2	-1.6	1.0	-1.3	-1.3	-0.7	-1.6	-1.7	-0.9	-0.6	-1.0	-1.4	-1.6	1.3	-1.7
Qualifications: None of the above	0.2	0.5	2.8	0.9	-0.2	-0.3	0.1	1.7	0.6	0.0	-0.0	0.5	0.8	0.6	-0.5	-1.2	0.3	-0.1
Financial difficulties in last 2 years	3.0	4.0	6.4	1.9	2.4	-1.5	2.5	2.5	1.0	2.2	2.2	1.9	1.8	2.1	2.0	0.0	-2.3	2.1
Mouth/teeth dental problems	0.4	0.6	1.3	0.3	-0.8	0.6	-0.9	-1.0	-1.1	-0.8	-0.9	-0.2	-0.6	-0.5	-0.8	0.4	0.8	-0.9
Heart attack	0.6	0.7	1.4	-0.6	0.8	-0.7	1.0	1.0	1.2	1.0	1.1	0.4	-0.1	-0.1	0.9	0.9	-0.9	1.1
Allergy	2.2	5.1	10.9	-1.4	-2.0	2.1	-1.9	-3.0	-2.5	-1.9	-1.8	-2.9	-2.0	-2.1	-2.2	-3.3	1.9	-1.8
Pain all over the body in last month	4.9	5.2	6.7	2.4	2.5	-2.3	2.4	1.4	2.5	2.2	2.2	2.3	2.1	2.5	2.6	1.8	-2.6	2.2
Diabetes (self-reported)	1.6	2.5	4.5	1.9	1.7	-1.1	2.0	0.0	1.1	2.1	2.1	1.4	1.4	1.8	1.1	0.7	-1.5	2.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.6	-0.4	-0.5	-0.1	-0.4	1.0	0.5	-0.4	-0.2	0.2	-0.1	-0.3	-0.1	1.3	0.5	-0.3
Medication: Ramipril	1.5	1.9	3.2	0.9	1.6	-0.9	1.7	1.7	1.2	1.8	1.6	1.4	1.4	1.1	0.8	0.5	-1.5	1.7
Medication: Simvastatin	4.3	6.2	8.7	0.7	2.8	-2.5	2.9	2.4	2.8	2.9	2.8	2.7	2.3	1.6	2.6	1.6	-3.0	2.8
Fluid intelligence score	3.3	6.9	11.9	-0.1	2.8	-2.9	3.1	2.7	3.5	3.0	2.6	2.8	1.0	2.0	3.3	1.8	-3.0	2.8
Illnesses of siblings	7.0	9.8	15.7	-1.6	-3.4	3.2	-3.7	-1.8	-3.3	-3.4	-3.2	-4.0	-2.9	-3.4	-3.7	-1.0	3.5	-3.3
Neuroticism score	10.5	21.9	29.5	-2.0	-5.3	4.8	-5.2	-2.7	-5.4	-5.4	-5.4	-4.3	-4.1	-3.3	-5.0	-4.9	5.2	-5.4
Weight	5.3	26.0	37.7	5.0	6.1	-4.3	6.0	1.3	3.4	5.8	5.8	5.0	6.1	5.3	5.5	1.1	-6.1	5.7
Impedance of arm (right)	0.6	2.9	6.3	-0.7	-1.5	1.9	-1.2	-1.0	-2.5	-1.1	-0.9	-2.3	-2.1	-1.9	-1.8	2.5	1.9	-0.9
Arm fat percentage (right)	6.6	26.2	37.7	4.3	6.1	-4.6	6.1	0.9	3.8	6.1	6.1	5.1	5.7	4.8	5.5	1.8	-6.0	6.1
Trunk fat-free mass	0.7	3.8	8.9	2.6	2.3	-1.3	1.9	0.4	0.7	1.8	1.8	1.7	3.0	2.5	2.1	-1.1	-2.5	1.7
Hip circumference	9.7	41.6	58.7	5.0	7.7	-5.8	7.6	1.9	5.1	7.5	7.4	6.9	7.0	6.6	7.2	2.4	-7.6	7.4
Time employed in main current job	0.2	0.3	0.9	0.9	0.4	0.0	0.4	0.1	-0.4	0.5	0.7	-0.1	0.3	-0.7	0.4	0.4	-0.7	0.6
Alcohol intake versus 10 years previously	2.4	3.6	5.0	1.1	2.2	-2.2	2.2	1.4	1.2	1.9	1.8	2.1	2.2	1.8	2.1	2.1	-2.1	1.8
Father’s age at death	2.0	2.7	3.9	-1.4	-1.8	1.7	-1.8	-1.1	-1.8	-1.8	-1.7	-1.4	-1.8	-1.6	-1.8	-0.6	2.0	-1.7
Worrier / anxious feelings	10.7	20.3	27.6	-2.5	-5.2	3.8	-4.9	-3.5	-4.1	-5.2	-5.2	-4.2	-4.2	-3.7	-5.0	-4.8	5.0	-5.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.4	0.1	0.3	0.3	0.4	0.7	0.3	-0.0	-0.4	0.1	-0.5	-0.0	0.2	-1.2	-0.4	-0.3
Falls in the last year	3.4	4.6	6.8	2.5	2.6	-1.7	2.5	0.3	1.6	2.5	2.5	2.4	1.6	2.1	2.4	0.8	-2.6	2.6
Hair/balding pattern: Pattern 3	2.8	4.1	7.2	-0.2	2.1	-1.8	2.4	0.4	1.8	2.6	2.6	1.8	1.6	2.0	2.1	2.4	-2.1	2.7
Number of live births	0.4	0.6	1.8	-0.6	-0.8	0.6	-0.7	1.0	-1.0	-0.6	-0.6	-0.7	-0.8	-0.3	-0.8	-1.4	0.8	-0.7
Forced expiratory volume in 1-second (FEV1)	8.6	28.8	40.1	-1.6	-6.1	5.9	-6.3	-2.3	-6.1	-6.2	-5.9	-5.7	-4.9	-3.8	-6.0	-4.8	6.0	-6.1
Pulse rate	0.8	1.4	4.8	2.2	0.9	-0.4	0.9	0.6	-0.1	0.7	0.8	1.3	2.0	1.8	0.8	1.3	-0.7	0.7
Happiness	1.9	2.4	4.7	-0.6	-1.5	1.8	-1.7	-1.4	-1.4	-2.0	-2.1	-1.3	-1.2	-0.5	-1.8	-0.5	1.6	-2.2
Noisy workplace	0.8	1.0	4.0	-2.0	-0.8	0.7	-0.9	-0.2	-0.6	-1.0	-0.9	-1.0	-0.6	-1.2	-0.9	-1.2	0.9	-1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.6	9.4	0.7	1.0	-1.1	0.8	0.2	1.7	0.9	0.9	0.9	0.5	0.9	1.5	3.1	-1.1	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.1	0.2	0.4	0.1	-0.1	-0.4	0.0	-0.2	-0.4	-0.4	0.0	0.1	-0.1	0.0	-0.0	-0.2	-0.4
Mouth/teeth dental problems: Dentures	0.2	0.3	1.2	0.6	-0.3	0.4	-0.2	-0.4	-0.1	-0.2	-0.2	-1.0	-0.1	-1.0	-0.5	-1.1	0.2	-0.2
Asthma	5.8	11.5	16.8	3.5	3.3	-3.2	3.4	1.6	3.6	3.5	3.4	3.8	4.1	3.8	3.0	3.5	-3.2	3.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.5	1.1	0.7	-1.1	1.2	-0.2	0.9	1.0	1.0	0.5	1.2	0.9	1.1	0.7	-0.7	1.1
Medication: Cholesterol lowering	6.2	9.6	14.4	1.3	3.7	-3.1	3.8	1.3	3.4	3.8	3.6	3.5	2.6	2.7	2.9	2.1	-3.5	3.6
Depression (self-reported)	0.4	0.5	1.6	1.3	-0.9	0.4	-0.5	-1.1	0.1	-0.7	-0.8	-0.3	-0.3	0.2	-0.9	-0.8	0.7	-0.8
Medication: Lansoprazole	0.5	0.6	1.4	0.0	0.6	-1.2	0.8	-0.0	1.2	0.9	0.9	0.9	0.5	0.6	0.8	0.1	-0.8	1.0
Prospective memory result	2.7	3.3	6.5	-1.1	-1.7	2.5	-1.7	-1.6	-2.4	-1.8	-1.9	-1.9	-1.1	-1.4	-2.0	-1.5	1.9	-1.9
Lung cancer (father)	0.9	1.1	5.2	0.7	-0.6	2.0	-0.5	-1.5	-2.3	-0.6	-0.6	-0.7	-0.2	0.6	-0.4	-0.7	0.8	-0.8
Illnesses of mother	1.2	1.5	2.3	0.5	-1.5	1.3	-1.3	-1.5	-0.7	-1.3	-1.3	-1.5	-0.9	-1.0	-1.4	-0.7	1.5	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	9.7	30.8	42.1	-1.9	-6.2	6.5	-6.4	-1.8	-6.5	-6.4	-6.0	-6.1	-5.2	-4.3	-6.1	-4.2	6.2	-6.2
Pulse wave Arterial Stiffness index	1.8	2.1	5.4	1.8	1.5	-1.3	1.5	-0.1	0.5	1.5	1.7	1.9	2.3	1.5	1.2	-0.2	-1.3	1.6
Impedance of arm (left)	0.5	2.5	7.2	-0.2	-1.3	1.9	-1.0	-0.5	-2.5	-0.9	-0.8	-1.9	-2.0	-1.6	-1.7	2.7	1.6	-0.8
Arm fat mass (right)	6.1	25.2	36.0	4.5	6.0	-4.5	6.0	0.6	3.6	5.9	5.9	4.9	5.9	5.0	5.5	1.2	-6.0	5.8
Trunk predicted mass	0.6	3.7	8.6	2.5	2.2	-1.2	1.9	0.4	0.6	1.7	1.7	1.7	2.9	2.5	2.1	-1.2	-2.4	1.6
Standing height	0.1	0.8	4.4	2.1	0.5	0.7	0.3	-0.3	-1.9	0.3	0.4	-0.7	0.8	0.7	0.1	1.2	-0.5	0.2
Length of working week for main job	0.4	0.4	1.7	0.9	-0.4	0.7	-0.4	-0.4	-0.6	-0.6	-0.6	-0.9	-1.3	-0.4	-0.5	-0.0	0.3	-0.6
Exposure to tobacco smoke at home	0.5	0.6	1.2	-0.8	0.6	-0.0	1.0	-0.9	-0.1	1.0	0.9	0.2	0.8	0.2	1.1	0.5	-0.7	0.9
Breastfed as a baby	3.7	4.5	8.4	1.6	2.4	-1.3	2.7	1.6	0.9	2.6	2.6	2.0	2.2	1.3	2.1	2.9	-2.2	2.6
Tense / ‘highly strung’	12.1	20.1	28.0	-2.5	-5.0	4.8	-5.0	-3.3	-4.5	-5.1	-5.2	-4.1	-4.2	-3.5	-4.7	-3.9	5.1	-5.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	3.9	6.0	-1.1	-2.2	2.1	-2.0	-1.1	-2.4	-2.1	-2.2	-1.4	-1.8	-1.8	-2.2	-2.1	2.3	-2.2
Hair/balding pattern: Pattern 4	0.3	0.8	2.1	0.5	-0.9	0.2	-1.2	-1.0	-0.1	-1.1	-0.9	0.0	0.5	-1.2	-1.4	-1.4	0.8	-1.0
Birth weight of first child	4.5	8.2	13.4	2.0	3.5	-2.0	3.2	0.7	1.7	3.1	3.0	3.1	2.9	3.7	3.4	2.8	-3.3	3.0
Peak expiratory flow (PEF)	1.7	3.8	7.0	-0.2	-2.2	1.8	-2.6	-0.2	-1.6	-2.4	-2.2	-2.0	-2.0	-1.0	-2.3	-2.5	1.9	-2.3
Pulse wave reflection index	0.2	0.2	1.4	0.4	0.1	-0.7	0.3	-0.7	0.1	0.3	0.5	-0.0	0.8	-0.0	0.0	-1.2	-0.1	0.4
Ever highly irritable/argumentative for 2 days	3.1	3.7	5.2	-1.1	-2.3	2.1	-2.1	-1.6	-1.5	-2.2	-2.1	-2.0	-1.8	-1.8	-2.0	-1.7	2.0	-2.1
Loud music exposure frequency	0.9	1.0	4.1	-1.4	0.9	-1.4	0.8	1.6	2.0	0.7	0.5	1.0	-0.2	-0.3	0.8	-0.1	-0.8	0.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.1	0.7	1.0	-0.4	0.8	1.0	0.4	0.9	0.9	0.6	0.6	0.5	1.1	1.5	-1.1	0.9
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	2.3	0.3	0.6	-0.3	0.9	1.5	0.1	0.7	0.8	0.7	0.9	0.9	0.8	0.4	-0.5	0.7
Blood clot in the leg (DVT)	1.8	2.3	4.4	-1.1	1.7	-2.1	1.5	1.4	2.0	1.5	1.2	2.0	1.1	0.5	1.7	1.4	-1.7	1.3
Medication: Paracetamol	2.6	4.4	6.5	1.4	2.5	-1.8	2.5	0.5	1.6	2.5	2.4	2.4	2.3	1.7	2.3	0.9	-2.5	2.5
Headache pain in last month	2.2	3.7	6.6	1.4	2.0	-1.8	2.1	0.8	2.3	2.0	1.8	2.5	2.2	2.6	1.9	0.7	-2.0	1.9
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	6.2	-0.9	-2.4	1.8	-2.3	-0.1	-1.8	-2.3	-2.3	-2.5	-1.7	-2.4	-1.9	-0.8	2.1	-2.2
Glaucoma (self-reported)	1.6	1.9	4.1	0.4	-1.6	0.9	-1.6	-1.1	-1.3	-1.5	-1.3	-1.7	-1.1	-1.3	-2.0	-1.1	1.6	-1.4
Gout (self-reported)	0.3	0.4	0.9	-0.7	-0.3	0.6	-0.3	0.0	-0.6	-0.6	-0.9	-0.6	-0.9	-0.1	-0.4	0.9	0.4	-0.8
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.5	0.9	-0.7	1.5	-0.7	-0.7	-1.6	-0.8	-0.9	-1.1	-0.3	0.1	-1.2	-0.5	1.0	-0.9
Medication: Amlodipine	0.5	0.8	2.1	-0.7	-0.8	1.4	-0.8	-0.7	-0.8	-0.7	-0.5	-0.7	-1.0	-0.8	-0.9	-1.1	1.0	-0.5
Medication: Ventolin 100micrograms inhaler	1.8	2.3	6.2	1.6	1.3	-1.1	1.3	-0.5	0.7	1.4	1.5	1.8	2.4	2.5	1.1	1.5	-1.2	1.4
Birth weight	0.4	0.8	2.0	-0.0	1.2	-0.1	1.1	0.4	0.3	1.2	1.3	0.5	1.0	0.3	1.1	-0.5	-1.4	1.3
Chronic bronchitis/emphysema (mother)	5.8	6.8	9.7	0.8	2.9	-3.1	3.1	1.2	2.7	3.0	2.8	2.5	2.7	1.1	2.8	2.8	-3.1	2.8
High blood pressure (siblings)	7.9	11.4	16.1	1.7	3.9	-3.3	4.0	2.6	2.9	3.9	3.7	4.0	2.7	3.3	3.9	1.3	-4.0	3.8
Forced vital capacity (FVC), Best measure	7.8	28.6	49.6	-0.8	-5.7	6.5	-6.0	-2.7	-7.0	-6.1	-5.7	-6.0	-4.5	-3.9	-6.0	-3.9	5.8	-5.9
Body fat percentage	7.4	29.2	44.1	4.1	6.5	-5.0	6.6	1.5	4.1	6.6	6.5	5.3	5.6	4.6	5.8	2.6	-6.4	6.5
Leg fat percentage (right)	7.1	25.7	37.4	3.3	5.9	-5.1	6.1	2.1	4.5	6.1	6.0	5.2	5.4	4.1	5.4	2.4	-5.9	6.0
Arm fat-free mass (right)	1.8	9.4	16.1	3.4	3.5	-2.7	3.3	1.4	2.1	3.1	3.1	3.0	4.0	3.4	3.5	-0.4	-3.8	3.0
Exposure to tobacco smoke outside home	1.6	2.2	3.2	1.0	1.5	-1.3	1.7	1.3	1.3	1.7	1.7	1.6	1.0	1.8	1.6	0.0	-1.6	1.8
Comparative body size at age 10	8.4	23.2	40.1	4.4	5.3	-4.2	5.2	2.0	4.1	5.2	5.0	5.3	6.3	4.4	5.3	3.6	-5.4	5.0
Number of full brothers	0.8	1.0	1.8	0.6	1.0	-1.1	1.3	1.0	1.0	1.1	1.1	0.7	0.5	0.7	1.3	-0.5	-1.3	1.2
Worry too long after embarrassment	2.8	4.7	8.9	-1.4	-2.6	3.0	-2.1	-1.6	-2.8	-2.2	-2.0	-2.1	-1.9	-1.3	-2.3	-1.8	2.6	-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.2	5.3	-1.2	-2.0	2.3	-1.3	-1.9	-2.3	-1.6	-1.7	-1.6	-2.0	-1.5	-1.5	-1.4	2.1	-1.8
Wheeze or whistling in the chest in last year	6.5	11.5	16.2	2.4	3.8	-3.4	4.0	1.3	3.9	4.0	3.7	3.5	3.6	2.9	3.4	2.2	-3.8	3.6
Number of children fathered	0.4	0.5	3.2	-1.8	0.3	-0.5	-0.1	1.2	1.0	-0.1	-0.4	-0.0	-0.4	-0.4	-0.0	-0.2	-0.5	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	3.1	-1.8	-0.5	0.9	-0.6	-1.4	-1.4	-0.5	-0.5	-1.3	-1.4	-1.5	-0.9	-0.0	0.3	-0.6
Age at first live birth	1.0	1.8	3.4	-0.1	-1.1	1.7	-1.7	-1.2	-1.8	-1.5	-1.4	-1.3	-1.5	-1.2	-1.3	0.3	1.3	-1.4
Pulse wave peak to peak time	1.8	2.1	5.0	-1.6	-1.5	1.4	-1.4	0.0	-0.6	-1.6	-1.7	-1.9	-2.2	-1.4	-1.2	0.3	1.3	-1.6
Health satisfaction	0.2	0.3	1.2	0.2	0.2	-1.0	0.3	-0.2	1.0	0.1	-0.0	0.1	0.4	-0.3	-0.4	-1.1	-0.3	0.1
Shortness of breath walking on level ground	0.5	0.6	1.8	-1.2	0.3	-1.0	0.5	1.2	1.2	0.4	0.1	0.0	-0.3	-1.4	0.3	-1.0	-0.5	0.2
Qualifications: College or University degree	0.3	0.9	3.6	-1.5	-0.8	0.7	-0.9	-0.5	0.0	-0.8	-0.6	-0.6	-1.5	-0.9	-0.1	1.9	0.8	-0.5
Eye problems/disorders: None of the above	0.1	0.2	0.9	-0.0	0.2	0.3	0.1	-0.1	0.0	0.2	0.2	1.0	0.4	0.8	0.5	-0.1	-0.3	0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.3	-0.3	0.5	0.4	0.9	-0.8	-1.0	0.9	1.2	-0.5	0.6	-0.0	0.3	-0.7	-0.4	1.1
Emphysema/chronic bronchitis	1.9	2.1	4.1	1.0	1.6	-0.9	1.8	0.5	0.6	1.9	2.0	1.2	1.4	1.5	1.8	1.0	-1.5	2.0
Medication for pain relief, constipation, heartburn	3.3	5.6	9.0	-1.2	-2.4	2.1	-3.0	-1.3	-2.2	-2.8	-2.6	-2.6	-2.7	-1.9	-2.6	-2.0	2.3	-2.7
Neck or shoulder pain in last month	1.1	1.6	3.5	0.8	1.6	-0.4	1.6	-0.3	0.9	1.4	1.4	1.1	1.9	0.8	1.7	0.3	-1.7	1.3
Medication: Blood pressure	0.4	0.7	2.2	1.0	0.9	0.1	0.8	-0.9	-0.2	0.8	1.0	1.1	0.8	1.5	0.6	-0.7	-0.7	0.9
Angina (self-reported)	0.7	1.0	3.2	-0.9	-1.0	1.7	-0.6	0.4	-0.8	-0.5	-0.6	-0.9	-1.0	-1.2	-0.8	-1.8	0.9	-0.6
Migraine (self-reported)	0.1	0.1	0.4	-0.6	0.1	-0.2	0.3	0.1	0.2	0.2	0.1	0.5	-0.5	-0.0	-0.0	-0.4	0.0	0.2
Medication: Ibuprofen	0.8	1.0	1.9	1.4	0.8	-1.1	1.1	0.1	0.8	1.0	1.0	0.7	1.3	1.2	1.2	0.8	-0.8	1.0
Medication: Allopurinol	0.8	1.0	2.7	-1.4	-0.9	0.3	-0.8	0.9	-0.2	-1.1	-1.3	-1.0	-1.6	-1.2	-1.0	0.5	0.9	-1.2
Medication: Omeprazole	0.1	0.1	0.3	0.0	0.2	0.6	0.4	0.2	-0.3	0.1	0.0	0.3	0.4	0.6	0.5	0.4	-0.0	0.0
Medication: Seretide 50 evohaler	1.1	1.3	2.1	1.2	1.1	-1.4	1.1	0.9	1.5	1.1	1.0	1.1	0.5	1.1	1.2	1.4	-1.2	1.0
Mean time to correctly identify matches	0.4	0.8	3.3	-0.8	0.8	-1.2	1.1	-1.8	0.4	1.1	1.0	0.9	0.2	-0.3	0.4	0.8	-0.5	1.1
Heart disease (mother)	0.8	1.0	4.9	-2.2	-0.4	0.5	-0.7	0.6	-0.3	-0.6	-0.6	-1.4	-1.2	-1.7	-0.8	-0.9	0.4	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.9	3.5	6.8	0.4	1.8	-2.5	1.9	2.2	2.6	2.0	1.9	2.1	1.6	0.9	1.7	1.2	-2.0	1.9
Whole body fat mass	6.4	26.8	39.4	4.3	6.2	-4.7	6.3	1.3	3.8	6.2	6.1	5.0	5.7	4.7	5.6	1.9	-6.2	6.1
Leg fat mass (right)	7.0	27.2	39.2	4.1	6.2	-5.1	6.2	1.6	4.2	6.1	6.0	5.2	5.8	4.6	5.7	1.8	-6.3	6.0
Arm predicted mass (right)	2.0	10.1	17.3	3.5	3.7	-2.8	3.4	1.5	2.1	3.2	3.2	3.1	4.2	3.6	3.6	-0.2	-4.0	3.2
Pulse rate, automated reading	4.8	15.4	32.7	5.7	3.7	-3.4	3.7	2.6	2.2	3.4	3.4	4.4	5.4	5.2	3.6	3.4	-3.8	3.3
Alcohol intake frequency.	2.4	5.7	16.1	3.5	2.4	-1.9	2.4	0.3	0.9	2.3	2.2	2.6	4.0	3.1	1.8	-0.6	-2.4	2.2
Comparative height size at age 10	0.1	0.4	2.0	0.5	0.8	0.4	0.5	0.9	-0.5	0.5	0.5	-1.4	-0.1	-0.4	0.0	0.5	-0.8	0.5
Number of full sisters	5.4	6.5	10.5	-0.1	3.1	-2.0	3.2	0.5	2.3	3.1	3.1	2.6	2.2	2.1	3.2	2.1	-3.1	3.1
Suffer from ‘nerves’	4.6	7.2	12.7	-2.9	-3.0	2.3	-2.9	-0.3	-1.3	-3.0	-3.0	-2.6	-3.6	-2.8	-2.6	-2.3	2.9	-2.9
Overall health rating	4.6	9.9	14.6	1.7	3.5	-3.6	3.8	2.6	3.3	3.4	3.2	3.3	3.8	3.3	2.9	0.5	-3.5	3.2
Chest pain or discomfort	2.4	3.5	5.5	1.3	1.9	-1.7	2.0	2.2	2.3	2.0	1.7	2.1	1.9	1.6	1.9	0.7	-2.1	1.7
Had major operations	0.7	0.8	2.5	-0.7	1.0	-0.5	1.2	1.6	0.0	1.2	1.3	0.3	-0.5	-0.4	0.6	0.2	-0.9	1.3
Age at last live birth	0.9	1.2	3.2	-1.0	-0.8	1.8	-1.1	-0.1	-1.5	-1.1	-1.1	-1.2	-1.6	-1.3	-0.7	-0.2	0.9	-1.0
Family relationship satisfaction	1.5	1.8	4.2	1.0	1.3	-0.7	1.5	0.1	1.2	1.5	1.3	1.3	1.0	1.9	1.5	2.0	-1.2	1.4
Leg pain on walking	3.6	4.5	8.4	-1.2	-1.7	2.3	-1.7	-2.9	-2.5	-1.8	-1.8	-2.5	-2.2	-2.2	-1.9	-2.9	1.8	-1.8
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	4.3	-2.1	-0.8	0.9	-0.9	-1.2	-1.1	-0.8	-0.7	-2.0	-1.4	-1.4	-0.6	-2.0	0.8	-0.7
Commuting to job workplace: Car/motor vehicle	1.4	1.6	4.5	-1.6	-1.1	1.4	-1.0	0.1	-0.5	-0.8	-0.9	-1.6	-2.1	-1.0	-1.2	-1.8	1.1	-0.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.6	-0.2	0.5	-1.2	0.6	-0.2	0.9	0.7	0.6	0.5	0.4	0.4	0.7	1.6	-0.5	0.7
Medication: Aspirin	2.0	2.6	5.0	-0.6	1.6	-1.1	2.0	1.1	1.8	2.2	2.2	1.7	1.0	1.1	1.6	1.1	-1.6	2.2
Supplements: Vitamin C	0.1	0.2	0.8	-0.4	-0.3	0.3	-0.2	0.0	-0.5	-0.3	-0.2	-0.7	-0.4	-0.9	-0.3	-0.0	0.3	-0.1
Knee pain experienced in last month	6.2	9.6	15.4	1.0	3.7	-2.5	3.9	0.7	2.8	3.9	3.6	3.5	2.6	2.9	3.8	1.6	-3.8	3.6
Hypertension (Self-reported)	3.9	11.0	16.6	2.9	3.9	-2.7	4.1	0.8	2.1	3.9	3.7	3.5	4.0	3.1	3.7	1.3	-4.0	3.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.3	0.8	-0.8	0.7	-0.8	-1.1	-0.7	-0.7	-0.6	-0.2	0.4	0.5	-0.6	-0.1	0.9	-0.6
Illnesses of father: Heart disease	0.7	1.0	6.3	-2.5	0.5	-0.9	0.7	-1.6	0.9	0.8	0.6	-0.4	-0.9	-1.0	0.4	0.3	-0.6	0.6
Illnesses of siblings: Diabetes	1.0	1.2	3.6	0.7	0.9	-1.7	1.2	-0.4	1.9	1.0	0.9	1.0	1.4	0.8	0.9	0.2	-1.1	1.1
Smoking status: Previous	1.6	2.4	4.2	-1.9	2.0	-0.8	1.8	1.8	1.6	1.9	1.7	0.7	-0.4	0.3	1.9	0.7	-2.0	1.9
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.5	0.2	-0.8	1.5	-1.1	-1.1	-1.9	-1.0	-0.8	-1.7	-1.1	-0.7	-0.9	-0.5	0.7	-0.9
Whole body fat-free mass	1.2	6.9	14.1	3.5	3.0	-2.0	2.7	0.6	1.3	2.5	2.5	2.4	3.8	3.4	2.9	-0.8	-3.3	2.4
Leg fat-free mass (right)	1.8	9.4	18.8	4.3	3.5	-2.2	3.1	0.4	1.5	2.9	2.9	2.9	4.2	4.1	3.4	-0.6	-3.6	2.8
Arm fat percentage (left)	6.7	26.8	38.6	4.7	6.1	-4.6	6.2	1.0	3.6	6.2	6.2	5.2	5.8	4.8	5.5	1.9	-6.1	6.1
Average weekly red wine intake	0.1	0.1	0.3	0.2	-0.6	-0.2	-0.4	-0.5	0.5	-0.4	-0.3	-0.2	-0.2	-0.6	-0.2	0.0	0.4	-0.3
Handedness (chirality/laterality): Left-handed	3.2	3.8	6.5	1.4	2.0	-1.8	2.2	0.3	1.9	2.1	1.9	2.4	1.6	2.5	2.5	1.6	-1.9	2.0
Mood swings	6.3	11.4	15.5	-1.3	-3.7	3.7	-3.7	-1.4	-3.6	-3.8	-3.8	-3.0	-3.1	-2.8	-3.7	-3.9	3.7	-3.9
Loneliness, isolation	4.1	5.7	13.3	-0.7	-2.6	2.0	-2.5	-0.5	-2.4	-2.8	-2.9	-2.2	-1.7	-1.8	-2.8	-3.6	2.5	-2.9
Long-standing illness, disability or infirmity	2.6	4.0	6.5	0.6	2.3	-2.2	2.5	1.2	2.5	2.2	2.0	1.7	2.0	1.2	2.1	1.7	-2.4	2.1
Ever had bowel cancer screening	0.2	0.2	1.2	-0.8	-0.5	0.3	0.1	-0.7	-0.1	-0.1	-0.4	-0.2	-0.4	-1.1	-0.5	-0.5	0.3	-0.3
Diabetes diagnosed by doctor	2.1	3.5	5.4	2.0	2.1	-1.5	2.3	0.8	1.8	2.3	2.3	1.8	1.4	2.1	1.4	0.8	-2.0	2.3
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	3.0	-0.8	-1.0	1.3	-1.1	0.3	-0.9	-1.2	-1.2	-1.4	-1.7	-1.2	-0.8	-0.9	1.0	-1.1
Friendships satisfaction	0.2	0.3	0.5	-0.2	-0.7	0.7	-0.5	-0.2	-0.5	-0.5	-0.7	-0.5	-0.0	0.2	-0.5	0.3	0.7	-0.7
Qualifications: nursing, teaching	0.2	0.2	2.2	-0.1	0.3	-0.3	0.2	-0.0	0.4	0.2	0.2	0.5	-0.3	0.3	0.6	1.5	-0.3	0.2
Commuting to job workplace: Walk	0.2	0.3	0.6	0.2	-0.6	-0.2	-0.5	0.7	-0.8	-0.6	-0.5	0.1	-0.2	-0.6	-0.2	0.5	0.5	-0.7
Eye problems/disorders: Cataract	0.4	0.5	2.0	0.6	0.8	-0.7	0.8	1.4	0.6	0.7	0.8	0.1	0.3	-0.2	0.6	0.5	-0.8	0.8
Mouth/teeth dental problems: Mouth ulcers	1.7	2.8	8.5	-2.9	1.7	-1.6	1.6	1.8	2.2	1.7	1.7	1.2	-0.1	0.5	1.8	0.6	-1.6	1.8
Medication for cholesterol	6.3	9.6	17.0	-1.7	-3.7	2.3	-4.1	-2.5	-2.2	-3.8	-3.5	-3.1	-2.7	-2.3	-3.7	-2.2	3.7	-3.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.5	-0.4	-0.8	0.7	-0.4	-0.3	-0.6	-0.8	-1.0	-0.8	-0.5	-0.6	-0.8	-1.2	0.6	-1.1
Back pain experienced in last month	1.5	2.3	6.4	1.2	1.3	-1.2	1.5	2.5	1.7	1.2	1.2	1.4	2.0	1.6	1.7	0.8	-1.4	1.1
Mineral and other dietary supplements	0.2	0.3	1.4	1.2	-0.0	0.2	0.0	-0.7	-0.2	0.3	0.6	0.4	0.6	1.0	-0.1	-0.3	0.2	0.5
Breast cancer (self-reported)	0.6	0.7	6.8	2.6	0.2	-0.2	0.1	-0.7	0.3	0.1	0.1	0.7	1.4	0.4	-0.3	0.6	-0.1	-0.0
Asthma (self-reported)	5.3	10.6	16.0	3.6	3.1	-3.0	3.2	1.2	3.4	3.3	3.3	3.7	4.0	3.8	2.9	3.4	-3.0	3.2
Osteoporosis (self-reported)	1.5	1.8	4.1	0.3	1.3	-1.5	1.4	2.0	0.5	1.4	1.9	0.9	1.1	0.8	1.4	1.2	-1.5	1.8
Osteoarthritis (self-reported)	0.3	0.4	3.0	-0.4	0.4	0.3	0.5	-1.7	-1.0	0.4	0.2	-0.3	-0.1	-0.9	0.3	0.4	-0.4	0.1
Medication: Aspirin	0.8	1.0	2.4	-0.4	1.0	-0.5	1.3	0.7	1.1	1.5	1.5	1.1	0.5	0.6	0.8	0.5	-1.0	1.6
Medication: Gliclazide	0.3	0.4	2.7	1.7	0.6	0.1	0.5	-0.2	-0.3	0.6	0.6	0.3	0.6	0.4	-0.2	0.0	-0.4	0.5
Illnesses of father: None of the above (group 1)	2.3	2.8	8.9	1.3	-1.7	2.6	-1.8	-1.1	-3.0	-1.7	-1.4	-1.7	-0.4	-1.0	-1.5	-1.2	1.7	-1.5
Smoking status: Current	0.1	0.2	0.9	0.0	0.8	-0.3	0.6	0.2	0.9	0.5	0.3	-0.2	-0.1	-0.1	0.3	-0.4	-1.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	14.1	29.8	41.9	-2.5	-6.3	5.5	-6.5	-2.7	-5.2	-6.3	-6.1	-5.5	-5.5	-4.6	-6.4	-4.1	6.4	-6.2
Whole body water mass	1.2	6.8	13.8	3.4	3.0	-1.9	2.7	0.6	1.3	2.5	2.5	2.4	3.7	3.3	3.0	-0.8	-3.3	2.4
Leg predicted mass (right)	1.8	9.6	18.7	4.3	3.5	-2.2	3.1	0.5	1.5	2.9	3.0	2.9	4.2	4.2	3.4	-0.5	-3.7	2.9
Arm fat mass (left)	6.6	27.2	38.9	4.8	6.2	-4.6	6.2	0.9	3.6	6.1	6.1	5.2	6.0	5.2	5.7	1.4	-6.2	6.0
Number of self-reported non-cancer illnesses	4.1	7.2	11.2	1.8	3.0	-2.6	3.3	1.2	2.2	3.2	3.0	2.9	3.0	2.2	2.9	2.1	-2.8	3.1
Average weekly champagne plus white wine intake	0.6	0.8	4.5	-2.1	0.4	-0.5	0.6	1.4	1.0	0.5	0.3	0.4	-1.0	-0.7	0.8	-0.1	-0.5	0.4
Miserableness	3.2	5.5	9.4	-1.5	-2.3	2.7	-2.4	-0.7	-2.4	-2.6	-2.6	-2.5	-3.1	-2.0	-2.1	-2.6	2.2	-2.6
Guilty feelings	2.9	4.4	7.8	0.4	-2.5	2.3	-2.3	-0.3	-2.6	-2.3	-2.3	-1.8	-1.3	-0.6	-2.5	-2.8	2.5	-2.3
Wears glasses or contact lenses	0.3	0.3	0.9	0.2	0.6	-0.5	0.8	-0.6	0.4	0.5	0.5	0.7	0.9	-0.1	0.6	-0.1	-0.5	0.5
Ever taken oral contraceptive pill	0.3	0.3	1.6	-1.3	-0.2	-0.3	-0.2	1.2	0.3	-0.1	-0.1	-0.5	-0.5	-0.6	-0.0	-0.6	0.1	-0.1
Hearing aid user	0.8	0.9	2.1	0.3	1.1	-1.1	0.8	0.1	1.5	0.8	0.7	1.1	0.9	1.2	0.9	-0.5	-1.1	0.8
Mother’s age at death	0.1	0.2	0.6	-0.7	0.8	0.4	0.2	0.1	-0.5	0.1	-0.1	0.2	-0.1	-0.1	0.1	0.7	-0.5	-0.1
Financial situation satisfaction	0.2	0.2	0.8	-0.2	0.2	0.7	0.3	0.2	-0.2	0.2	0.0	0.9	0.0	0.9	0.5	-0.6	-0.2	0.0
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.2	0.2	0.2	-0.8	0.2	0.0	1.0	0.2	0.2	0.6	1.1	0.2	0.1	-0.5	-0.2	0.2
Commuting to job workplace: Public transport	0.6	0.8	3.7	1.9	0.6	-0.7	0.6	0.3	-0.0	0.7	0.8	1.1	1.4	0.4	0.7	0.5	-0.6	0.9
Eye problems/disorders: Glaucoma	2.0	2.3	4.2	0.7	-1.8	1.3	-1.7	-1.3	-1.8	-1.5	-1.4	-1.9	-1.1	-1.2	-2.1	-0.9	1.9	-1.5
Medication: Blood pressure	2.9	5.4	9.9	2.5	2.7	-1.4	3.2	1.1	1.1	3.0	2.8	1.9	2.9	1.9	2.5	1.1	-2.6	2.7
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.6	0.2	-0.2	0.6	0.8	-0.4	-0.1	0.7	0.6	-0.0	-0.0	0.2	0.1	-0.5	0.0	0.5
Supplements: Fish oil (including cod liver oil)	1.5	1.9	4.0	-1.7	-1.2	0.7	-1.4	-0.4	-0.7	-1.6	-2.0	-1.4	-1.5	-1.6	-1.3	-1.2	1.2	-2.0
High cholesterol (Self-reported)	7.5	13.3	18.1	2.7	3.7	-3.6	4.1	2.3	4.2	4.0	3.9	4.3	3.6	3.5	3.6	2.5	-3.7	4.0
Medication: Bendroflumethiazide	2.9	4.4	9.0	2.6	2.2	-1.1	2.5	-1.0	0.2	2.5	2.5	2.4	3.0	1.9	2.2	0.5	-2.1	2.4
Medication: Paracetamol	2.2	3.4	5.2	1.1	2.1	-2.0	2.0	1.3	1.8	2.1	1.9	2.2	2.3	1.6	1.9	0.5	-2.1	2.0
Medication: Lisinopril	0.8	1.1	2.9	1.5	0.9	-0.6	1.2	0.6	-0.1	1.1	1.1	1.2	1.1	1.7	1.0	0.4	-0.8	1.1
Medication: Atorvastatin	6.2	7.6	11.8	2.9	2.6	-2.3	3.1	2.0	2.2	3.1	3.1	3.3	2.8	3.4	2.4	1.8	-2.4	3.1
Illnesses of father: High blood pressure	1.2	1.5	3.5	-0.6	1.4	-1.7	1.5	1.3	1.9	1.3	1.1	0.8	-0.2	-0.2	1.4	-0.2	-1.6	1.1
Alcohol drinker status: Never	0.1	0.1	0.4	0.4	-0.5	-0.3	-0.2	0.1	-0.3	-0.2	-0.1	-0.0	0.6	-0.3	-0.4	-0.4	0.2	-0.2
Ever smoked	0.8	1.4	5.9	-2.4	1.2	-0.1	1.3	1.1	1.1	1.3	1.1	-0.1	-1.0	-0.7	1.2	-0.2	-1.3	1.2
Basal metabolic rate	2.0	10.8	19.4	4.0	3.9	-2.6	3.6	0.8	1.8	3.4	3.4	3.0	4.4	3.9	3.6	-0.4	-4.1	3.3
Leg fat percentage (left)	7.3	26.4	37.5	3.8	6.0	-5.1	6.1	1.8	4.5	6.1	5.9	5.4	5.6	4.5	5.4	2.2	-6.0	5.9
Arm fat-free mass (left)	1.9	9.4	15.6	3.1	3.7	-2.6	3.5	0.9	2.0	3.2	3.2	2.9	4.0	3.4	3.5	-0.5	-3.9	3.1
Number of operations (self-reported)	0.9	1.4	2.1	1.4	1.2	-0.6	1.4	1.3	0.6	1.4	1.4	1.1	1.3	1.5	0.8	-0.1	-1.2	1.3
Average weekly beer plus cider intake	0.3	0.5	1.6	-1.3	-0.6	0.6	-0.4	-0.8	-0.3	-0.6	-0.8	-0.4	-1.2	0.0	-0.6	-0.0	0.7	-0.7
Irritability	12.9	21.9	30.1	-2.5	-5.0	5.3	-5.2	-1.8	-5.5	-5.2	-5.1	-4.6	-5.1	-3.6	-4.6	-4.6	5.0	-5.2
Risk taking	0.9	1.4	3.1	-0.4	1.5	-1.0	1.4	1.4	1.7	1.3	1.1	1.2	0.0	0.6	1.1	0.9	-1.3	1.2
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.3	-0.4	-0.5	0.4	-0.5	-0.3	-0.6	-0.6	-0.9	-0.6	-0.3	-1.0	-1.1	-0.5	0.5	-0.9
Fractured/broken bones in last 5 years	5.7	7.4	12.3	1.3	2.9	-2.8	2.9	2.9	2.6	2.7	2.6	3.5	2.3	2.9	3.2	1.4	-3.0	2.6
Age started oral contraceptive pill	0.5	0.6	2.4	0.9	0.7	-0.5	0.7	-0.3	0.1	0.6	0.6	1.0	1.6	0.9	0.9	0.9	-0.6	0.6
Diastolic blood pressure, automated reading	5.3	16.5	32.4	5.7	4.2	-2.8	4.2	1.3	1.8	4.1	4.1	4.6	5.6	5.3	4.1	1.6	-4.2	3.9
Ever depressed for a whole week	2.7	3.4	5.4	-1.3	-2.3	1.4	-2.1	-1.0	-1.3	-2.2	-2.1	-1.7	-1.6	-2.0	-1.9	-1.6	2.0	-2.2
Unable to work because of sickness or disability	2.0	2.6	5.0	1.4	2.2	-1.2	2.0	-0.6	0.8	1.9	1.8	1.4	1.7	1.6	1.5	-0.2	-2.2	1.9
Commuting to job workplace: Cycle	0.3	0.4	1.6	0.2	0.4	-0.6	0.5	-0.5	0.7	0.6	0.7	0.8	0.4	-0.0	0.7	1.3	-0.4	0.8
Myopia	5.3	7.7	10.0	1.1	2.9	-2.8	3.2	3.0	2.8	3.1	3.1	3.0	2.8	2.2	2.8	2.3	-2.7	3.1
Vascular/heart problems diagnosed by doctor	3.7	10.1	14.8	-2.9	-3.7	2.7	-3.8	-1.1	-2.1	-3.8	-3.6	-3.5	-3.8	-2.9	-3.5	-0.8	3.8	-3.6
Cholesterol lowering medication	9.2	13.5	19.1	2.3	4.0	-3.2	4.4	3.3	3.3	4.2	4.0	4.0	3.6	3.1	4.0	2.5	-4.1	4.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.7	0.6	0.7	-0.2	0.7	-0.2	0.5	0.6	0.5	0.7	0.7	0.7	0.8	0.8	-0.5	0.5
Pain experienced in last month	8.4	14.1	20.2	-2.1	-4.2	3.0	-4.4	-2.2	-3.8	-4.3	-4.1	-4.0	-3.7	-3.7	-4.5	-2.5	4.3	-4.1
Supplements: Calcium	0.6	0.6	2.7	1.6	0.4	-0.8	0.5	-0.3	0.9	0.4	0.5	1.0	1.1	0.7	0.8	0.5	-0.6	0.5
Basal cell carcinoma (self-reported)	0.4	0.4	1.0	-1.0	-0.5	0.1	-0.7	0.2	0.2	-0.8	-0.9	-0.8	-0.9	-0.8	-0.4	-0.2	0.4	-0.9
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.0	-0.3	0.8	-0.6	0.9	0.9	1.0	1.0	1.0	0.4	-0.1	-0.0	0.9	0.8	-0.9	1.0
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	4.1	-1.2	1.7	-2.0	1.5	1.4	2.0	1.5	1.1	1.9	1.0	0.4	1.7	1.4	-1.7	1.3
Heart disease (siblings)	0.3	0.3	3.5	-0.1	-0.1	0.5	0.3	0.6	0.3	0.1	-0.1	0.3	0.2	0.4	0.0	-1.9	0.0	0.0
Alcohol drinker status: Previous	0.3	0.4	1.5	1.2	0.5	-0.3	0.6	-0.4	0.6	0.7	0.7	0.3	0.2	0.7	0.2	-0.9	-0.5	0.7
Pack years of smoking	2.6	3.8	9.0	0.5	2.0	-3.0	2.0	1.9	2.5	1.9	1.9	1.6	1.7	1.4	2.1	1.5	-2.3	1.9
Impedance of whole body	0.6	3.2	7.6	-1.1	-1.6	1.7	-1.2	-0.3	-2.1	-1.0	-0.9	-2.2	-2.6	-2.3	-1.9	2.8	1.9	-0.9
Leg fat mass (left)	7.3	28.4	41.0	4.3	6.3	-5.2	6.3	1.4	4.4	6.2	6.1	5.5	6.0	4.9	5.8	1.9	-6.4	6.0
Arm predicted mass (left)	2.2	11.1	17.9	3.2	4.0	-3.0	3.7	1.2	2.5	3.5	3.5	3.1	4.1	3.7	3.8	-0.3	-4.2	3.4