[Hub]/) : Traits : Pulse rate, automated reading :

chr19:40,000,075-41,953,928

Best TWAS P=1.59e-13 · Best GWAS P=1.77e-14 conditioned to 0.276

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C19orf47 0.05 0.04 lasso 3 0.04 2.4e-05 6.9 6.9 3.9e-12 -0.68 0.07 0.88 FALSE
2 CommonMind Brain Pre-frontal Cortex C19orf54 0.06 0.02 bslmm 432 0.02 6.6e-04 0.7 5.1 2.8e-07 -0.23 0.28 0.22 TRUE
3 GTEx Adipose Subcutaneous MAP3K10 0.18 0.15 enet 27 0.19 2.6e-15 4.6 -5.8 8.3e-09 0.44 1.00 0.00 FALSE
4 GTEx Breast Mammary Tissue (Female) MAP3K10 0.42 0.15 lasso 9 0.10 5.6e-04 4.6 -5.9 3.0e-09 0.50 0.15 0.25 FALSE
5 GTEx Cells EBV-transformed lymphocytes MAP3K10 0.28 0.15 lasso 6 0.16 9.0e-06 -6.6 -6.6 3.3e-11 0.82 0.15 0.80 FALSE
6 GTEx Cells Transformed fibroblasts C19orf47 0.10 0.02 enet 11 0.02 1.0e-02 -7.7 6.1 9.5e-10 -0.73 0.00 0.98 FALSE
7 GTEx Esophagus Mucosa C19orf47 0.09 0.06 lasso 6 0.04 6.1e-04 -7.7 6.8 9.1e-12 -0.94 0.01 0.95 FALSE
8 GTEx Esophagus Muscularis PLD3 0.09 0.09 lasso 5 0.09 3.1e-06 6.8 6.7 2.4e-11 -0.73 0.01 0.98 FALSE
9 GTEx Lung MAP3K10 0.13 0.13 lasso 5 0.13 4.6e-10 4.6 -5.9 3.9e-09 0.61 0.75 0.25 FALSE
10 GTEx Muscle Skeletal PLD3 0.11 0.09 lasso 4 0.10 7.7e-10 -5.9 7.3 2.4e-13 -0.91 0.02 0.98 FALSE
11 GTEx Testis C19orf47 0.22 0.14 lasso 3 0.15 3.0e-07 -6.5 7.4 1.6e-13 -0.93 0.01 0.98 TRUE
12 GTEx Whole Blood MAP3K10 0.12 0.03 lasso 6 0.02 5.6e-03 -6.5 -6.0 2.4e-09 0.75 0.28 0.68 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C19orf47 0.04 0.01 blup 53 0.02 8.9e-04 6.6 6.6 3.9e-11 -0.76 0.01 0.73 TRUE
14 The Cancer Genome Atlas Lung Adenocarcinoma C19orf47 0.03 0.02 blup 53 0.01 1.3e-02 7.6 5.5 4.8e-08 -0.54 0.01 0.88 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma C19orf47 0.13 0.05 lasso 5 0.08 1.1e-08 -2.7 5.4 6.3e-08 -0.65 0.22 0.78 FALSE