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chr19:40,000,075-41,953,928

Best TWAS P=1.59e-13 · Best GWAS P=1.77e-14 conditioned to 0.276

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Testis	C19orf47	0.22	0.14	lasso	3	0.15	3.0e-07	-6.5	7.4	1.6e-13	-0.93	0.01	0.98	TRUE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C19orf47	0.04	0.01	blup	53	0.02	8.9e-04	6.6	6.6	3.9e-11	-0.76	0.01	0.73	TRUE
2	CommonMind	Brain Pre-frontal Cortex	C19orf54	0.06	0.02	bslmm	432	0.02	6.6e-04	0.7	5.1	2.8e-07	-0.23	0.28	0.22	TRUE
10	GTEx	Muscle Skeletal	PLD3	0.11	0.09	lasso	4	0.10	7.7e-10	-5.9	7.3	2.4e-13	-0.91	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C19orf47	0.05	0.04	lasso	3	0.04	2.4e-05	6.9	6.9	3.9e-12	-0.68	0.07	0.88	FALSE
7	GTEx	Esophagus Mucosa	C19orf47	0.09	0.06	lasso	6	0.04	6.1e-04	-7.7	6.8	9.1e-12	-0.94	0.01	0.95	FALSE
8	GTEx	Esophagus Muscularis	PLD3	0.09	0.09	lasso	5	0.09	3.1e-06	6.8	6.7	2.4e-11	-0.73	0.01	0.98	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	MAP3K10	0.28	0.15	lasso	6	0.16	9.0e-06	-6.6	-6.6	3.3e-11	0.82	0.15	0.80	FALSE
6	GTEx	Cells Transformed fibroblasts	C19orf47	0.10	0.02	enet	11	0.02	1.0e-02	-7.7	6.1	9.5e-10	-0.73	0.00	0.98	FALSE
12	GTEx	Whole Blood	MAP3K10	0.12	0.03	lasso	6	0.02	5.6e-03	-6.5	-6.0	2.4e-09	0.75	0.28	0.68	FALSE
4	GTEx	Breast Mammary Tissue (Female)	MAP3K10	0.42	0.15	lasso	9	0.10	5.6e-04	4.6	-5.9	3.0e-09	0.50	0.15	0.25	FALSE
9	GTEx	Lung	MAP3K10	0.13	0.13	lasso	5	0.13	4.6e-10	4.6	-5.9	3.9e-09	0.61	0.75	0.25	FALSE
3	GTEx	Adipose Subcutaneous	MAP3K10	0.18	0.15	enet	27	0.19	2.6e-15	4.6	-5.8	8.3e-09	0.44	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	C19orf47	0.03	0.02	blup	53	0.01	1.3e-02	7.6	5.5	4.8e-08	-0.54	0.01	0.88	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	C19orf47	0.13	0.05	lasso	5	0.08	1.1e-08	-2.7	5.4	6.3e-08	-0.65	0.22	0.78	FALSE