TWAS hub - MAP3K10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1810	0.0520	1.9e-06	0.148	NA	0.189	NA	0.160	4.0e-12	NA	2.6e-15	NA	4.9e-13
2	GTEx	Artery Aorta	0.1980	0.0690	2.8e-03	0.084	NA	0.046	NA	0.053	2.2e-05	NA	1.5e-03	NA	7.0e-04
3	GTEx	Breast Mammary Tissue	0.1680	0.0620	3.2e-03	0.115	NA	0.063	NA	0.067	1.6e-06	NA	3.8e-04	NA	2.4e-04
4	GTEx	Breast Mammary Tissue (Female)	0.4240	0.1241	1.6e-03	0.146	NA	0.023	NA	0.103	4.0e-05	NA	7.0e-02	NA	5.6e-04
5	GTEx	Cells EBV-transformed lymphocytes	0.2780	0.0740	5.9e-05	0.151	NA	0.111	NA	0.156	1.3e-05	NA	1.9e-04	NA	9.0e-06
6	GTEx	Lung	0.1290	0.0454	3.0e-04	0.131	NA	0.120	NA	0.129	3.2e-10	NA	2.0e-09	NA	4.6e-10
7	GTEx	Nerve Tibial	0.1278	0.0437	5.0e-04	0.160	NA	0.139	NA	0.155	1.8e-11	NA	4.6e-10	NA	3.9e-11
8	GTEx	Prostate	0.3280	0.1250	4.2e-03	0.143	NA	0.185	NA	0.206	2.0e-04	NA	2.1e-05	NA	6.7e-06
9	GTEx	Skin Sun Exposed Lower leg	0.0810	0.0320	3.1e-03	0.115	NA	0.096	NA	0.107	9.9e-10	NA	2.6e-08	NA	3.5e-09
10	GTEx	Whole Blood	0.1220	0.0460	3.9e-04	0.025	NA	0.009	NA	0.020	1.9e-03	NA	4.2e-02	NA	5.6e-03
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0247	0.0145	4.4e-03	0.008	0.015	0.003	NA	0.004	3.5e-02	0.0067	1.5e-01	NA	1.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Pulse rate, automated reading	8.4	27.3	44.0	-5.8	-4.4	-4.6	-5.9	-6.6	-5.9	-4.6	-4.1	-4.6	-6.0	-4.4
Blood Eosinophil Count	6.7	51.6	458.0	-3.9	-2.2	-3.4	-3.3	-4.1	-3.7	-3.3	-21.4	-3.3	-2.9	-2.5
Supplements: Zinc	6.7	7.2	11.2	2.2	3.3	3.3	2.8	2.1	3.1	3.3	1.4	3.3	2.3	1.5
Number of children fathered	4.3	4.9	8.1	2.1	2.2	2.2	1.9	2.4	2.5	2.2	0.2	2.2	2.3	2.9
Worry (Nagel 2018)	3.9	8.3	11.3	-3.4	-3.0	-3.1	-3.1	-2.3	-3.2	-3.1	-2.6	-3.1	-1.3	-2.7
Financial difficulties in last 2 years	3.8	5.1	8.3	2.9	2.2	2.2	2.2	2.1	2.3	2.2	1.8	2.2	2.2	2.4
Qualifications: College or University degree	3.8	11.9	21.1	-2.7	-3.3	-3.4	-3.1	-4.2	-3.6	-3.4	-3.0	-3.4	-4.6	-2.8
Pulse rate	3.7	6.2	11.5	-2.7	-2.0	-2.0	-3.4	-2.9	-2.5	-2.0	-2.2	-2.0	-2.8	-2.5
Ever taken oral contraceptive pill	3.7	4.1	5.2	1.9	2.0	2.2	1.9	2.2	2.3	2.2	1.7	2.2	0.8	2.3
Medication: Aspirin	3.5	4.6	7.9	-2.1	-1.6	-1.8	-1.6	-2.8	-2.1	-1.8	-2.5	-1.8	-2.6	-2.4
Medication: Aspirin	3.5	4.5	7.3	-2.2	-1.7	-1.9	-1.5	-2.7	-2.1	-1.9	-2.4	-1.9	-2.5	-2.3
Ever highly irritable/argumentative for 2 days	3.3	3.9	5.6	2.1	2.4	2.0	2.2	1.7	2.0	2.0	1.6	2.0	2.0	1.8
Suffer from ‘nerves’	3.2	5.0	7.5	-2.7	-2.6	-2.5	-2.4	-2.0	-2.6	-2.5	-1.3	-2.5	-1.3	-1.2
Depression (Nagel 2018)	3.1	4.7	7.3	2.2	2.6	2.7	2.1	1.3	2.3	2.7	1.2	2.7	2.1	0.7
Exposure to tobacco smoke at home	2.9	3.3	4.3	1.6	1.9	1.9	1.9	1.7	2.0	1.9	2.1	1.9	1.2	1.8
Age started oral contraceptive pill	2.8	3.5	5.8	-1.8	-2.3	-2.2	-2.1	-1.3	-2.4	-2.2	-1.0	-2.2	-1.5	-0.8
Birth weight	2.7	5.9	17.9	0.5	0.1	0.6	-0.1	4.2	0.9	0.6	4.0	0.6	4.2	3.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.4	5.6	1.6	2.0	2.4	2.0	0.9	2.0	2.4	1.2	2.4	1.5	1.4
Prospective memory result	2.6	3.2	4.3	1.5	1.7	1.9	1.8	1.9	2.1	1.9	1.5	1.9	1.4	1.7
Current tobacco smoking	2.5	4.1	7.2	1.5	2.7	2.6	1.9	1.0	2.4	2.6	0.6	2.6	0.5	1.8
Commuting to job workplace: Car/motor vehicle	2.5	2.8	4.6	1.7	1.6	1.7	2.0	1.9	1.7	1.7	1.1	1.7	2.1	1.0
Alcohol drinker status: Never	2.5	3.0	5.5	-2.3	-1.8	-1.7	-1.4	-1.7	-1.8	-1.7	-0.9	-1.7	-1.4	-2.1
Fasting Glucose	2.4	2.9	4.5	1.0	2.0	1.9	1.5	1.8	1.4	1.8	1.6	1.8	1.4	2.1
Diabetes (father)	2.4	3.0	4.8	1.0	2.2	2.1	2.2	1.3	2.1	2.1	1.2	2.1	0.4	0.5
Nervous feelings	2.4	4.5	6.7	-2.2	-2.5	-2.4	-2.2	-1.9	-2.6	-2.4	-0.6	-2.4	-0.7	-2.3
Smoking Status	2.3	5.5	8.4	1.7	2.9	2.9	1.7	2.2	2.9	2.9	0.5	2.9	1.6	2.3
Guilty feelings	2.3	3.5	6.0	1.5	2.2	2.3	2.5	-0.4	1.7	2.4	1.5	2.4	-0.7	-1.7
Bilateral oophorectomy (both ovaries removed)	2.2	2.5	7.0	1.3	2.0	1.9	2.6	0.7	1.9	1.9	0.2	1.9	0.2	-0.2
Smoking status: Current	2.2	3.4	5.7	1.4	2.4	2.4	1.6	1.0	2.2	2.4	0.8	2.4	0.6	1.9
Frequency of depressed mood in last 2 weeks	2.1	2.9	6.9	1.2	1.8	1.8	1.3	1.6	1.5	1.8	0.7	1.8	2.6	1.8
Diastolic blood pressure, automated reading	2.1	6.6	10.5	-2.1	-2.9	-2.9	-3.2	-2.2	-3.2	-2.9	-2.0	-2.9	-1.2	-2.1
Medication: Ramipril	2.0	2.6	4.1	-1.9	-1.1	-1.5	-1.6	-1.5	-1.6	-1.5	-2.0	-1.5	-1.4	-1.8
Mineral and other dietary supplements	2.0	2.7	5.1	-1.1	-2.3	-2.2	-1.6	-0.6	-2.0	-2.2	-1.0	-2.2	0.4	-0.4
Average weekly champagne plus white wine intake	2.0	2.8	5.6	2.2	1.8	1.9	2.4	1.1	1.9	1.9	0.6	1.9	0.6	0.9
Heart disease (siblings)	2.0	2.5	4.1	-1.4	-1.5	-1.8	-1.7	-1.1	-1.9	-1.8	-0.5	-1.8	-1.1	-2.0
Type 2 Diabetes (T2D) (2012)	1.9	2.2	3.6	1.9	1.7	1.9	1.3	0.1	1.9	1.9	0.6	1.9	-0.3	1.2
Sensitivity / hurt feelings	1.9	3.2	4.5	-1.9	-2.0	-1.8	-2.1	-2.0	-1.9	-1.8	-0.6	-1.8	-2.0	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	5.1	-1.7	-1.7	-2.0	-2.3	-1.5	-2.1	-2.0	-0.9	-2.0	-1.2	-0.7
Irritable Bowel Disease (IBD)	1.8	4.4	11.2	1.9	1.7	1.6	1.7	3.3	2.0	1.6	1.8	1.6	2.9	2.2
Ulcerative Colitis (UC)	1.8	3.3	7.8	1.6	1.6	1.4	1.6	2.8	1.8	1.4	1.1	1.4	2.0	2.5
Diabetes (mother)	1.8	2.3	3.9	1.2	1.8	2.0	1.3	1.0	1.5	2.0	1.7	2.0	1.0	0.4
Lung cancer (father)	1.8	2.1	4.2	-1.1	-1.0	-1.3	-2.0	-2.1	-1.5	-1.3	-0.5	-1.3	-1.7	-1.7
Average weekly red wine intake	1.8	2.6	5.9	-1.7	-1.8	-1.9	-2.4	-1.2	-1.7	-1.9	-0.7	-1.9	-0.7	-1.2
Qualifications: nursing, teaching	1.8	2.8	11.4	0.0	-0.6	-0.6	-0.1	-2.9	-1.0	-0.5	-0.9	-0.5	-3.4	-2.9
Fractured/broken bones in last 5 years	1.8	2.3	3.8	1.4	2.0	1.8	1.9	0.1	1.7	1.8	1.0	1.8	-0.8	1.2
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	3.2	-1.5	-1.2	-1.1	-1.8	-1.6	-1.5	-1.1	-1.6	-1.1	-1.4	-1.7
Time employed in main current job	1.7	1.9	5.3	-2.3	-1.4	-1.4	-1.6	-1.1	-1.4	-1.4	-1.5	-1.4	-0.3	-0.4
Waist Hip Ratio (WHR)	1.6	7.3	14.7	-2.1	-2.8	-2.9	-3.0	-3.8	-3.3	-2.8	-1.1	-2.8	-2.8	-0.5
Medication for hormone replacement therapy	1.6	1.8	3.3	1.8	1.7	1.6	1.7	0.1	1.3	1.6	0.7	1.6	-0.1	0.7
Taking other prescription medications	1.6	2.5	8.8	-1.7	-0.8	-0.8	-1.4	-2.6	-1.2	-0.8	-0.3	-0.8	-3.0	-1.5
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.4	1.0	1.1	1.2	0.7	-1.2	0.7	1.2	0.7	1.2	-1.8	-2.1
Number of incorrect matches in round	1.5	2.5	4.3	1.0	2.0	1.9	2.1	1.4	1.6	1.9	0.5	1.9	1.2	0.5
Medication: Simvastatin	1.5	2.2	7.2	-0.0	-0.9	-1.0	-0.5	-2.3	-1.0	-1.0	-0.4	-1.0	-2.7	-2.6
Gout (self-reported)	1.5	2.1	6.0	1.9	1.5	1.5	1.1	-0.1	1.4	1.5	2.4	1.5	-0.6	-0.0
Average weekly beer plus cider intake	1.5	2.1	4.2	1.8	2.1	1.8	1.4	0.2	1.7	1.8	0.9	1.8	-0.1	-0.2
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	4.6	0.7	0.9	0.9	1.0	2.2	1.0	0.8	0.9	0.8	1.5	2.0
Past tobacco smoking	1.4	2.5	3.9	-1.4	-1.8	-1.9	-0.7	-2.0	-2.0	-1.9	-0.2	-1.9	-1.4	-1.5
Worrier / anxious feelings	1.4	2.6	4.3	-2.0	-2.0	-1.9	-2.1	-0.2	-2.1	-1.9	-1.1	-1.9	0.0	-0.0
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	6.0	-1.3	-1.7	-1.5	-1.8	-2.2	-1.8	-1.5	-0.3	-1.5	-2.5	-0.8
Wheeze or whistling in the chest in last year	1.4	2.5	4.2	0.5	2.0	2.0	1.1	1.9	1.8	2.1	0.6	2.1	1.5	0.6
Wears glasses or contact lenses	1.4	1.7	4.9	0.5	1.2	1.4	1.3	-0.8	0.9	1.4	0.7	1.4	-1.6	-2.2
Commuting to job workplace: Cycle	1.4	1.7	3.7	0.9	0.9	1.1	1.4	1.8	1.3	1.1	-0.0	1.1	1.9	1.6
Mean Putamen Volume	1.3	1.5	3.4	1.8	1.5	1.5	1.0	0.1	1.5	1.5	0.7	1.5	0.0	-0.5
Hypothyroidism (self reported)	1.3	3.1	6.7	-1.6	-1.7	-1.6	-1.8	-2.5	-1.9	-1.6	-0.9	-1.6	-2.6	-0.8
Hearing difficulty/problems: Yes	1.3	2.0	4.1	-1.1	-1.8	-1.5	-2.0	-1.4	-1.6	-1.4	-0.6	-1.4	-0.7	-1.5
Ever smoked	1.3	2.3	3.6	1.3	1.7	1.7	0.7	1.7	1.7	1.7	0.3	1.7	1.3	1.9
Ever had prostate specific antigen (PSA) test	1.3	1.5	3.5	1.1	1.4	1.3	1.9	1.1	1.5	1.3	0.6	1.3	0.1	1.1
Ulcerative Colitis	1.2	1.8	2.5	1.5	1.6	1.5	1.5	1.6	1.5	1.5	0.1	1.5	0.8	0.2
Townsend deprivation index at recruitment	1.2	1.7	2.5	-1.5	-1.6	-1.3	-1.6	-1.3	-1.5	-1.3	1.3	-1.3	-0.8	-0.5
Mouth/teeth dental problems: Dentures	1.2	2.0	5.0	-1.4	-1.0	-1.3	-0.9	-1.7	-1.5	-1.3	-0.5	-1.3	-1.8	-2.2
Depression (self-reported)	1.2	1.5	3.7	-1.6	-1.5	-1.2	-1.9	-0.9	-1.3	-1.2	-0.9	-1.2	0.4	0.2
Pulse wave reflection index	1.2	1.5	2.9	0.9	1.4	1.3	1.7	0.7	1.4	1.3	0.8	1.3	0.8	1.5
Comparative body size at age 10	1.2	3.4	5.5	1.7	1.8	1.8	1.6	2.1	1.5	1.8	1.3	1.8	2.4	2.3
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	2.4	1.1	1.4	1.5	1.6	-1.1	1.2	1.5	-0.4	1.5	-0.9	-0.0
Prostate Cancer	1.1	1.6	4.4	-2.1	-1.3	-1.1	-1.2	-0.7	-1.4	-1.1	-0.1	-1.1	-1.2	-1.6
LDL Cholesterol	1.1	1.8	3.9	-1.3	-1.4	-1.5	-2.0	-0.3	-1.4	-1.5	-1.9	-1.5	0.3	0.2
Rheumatoid Arthritis	1.1	1.6	3.1	-1.4	-1.3	-1.5	-1.8	0.2	-1.2	-1.5	-1.4	-1.5	0.0	0.3
Lung FEV1/FVC ratio	1.1	5.3	10.6	3.3	2.4	2.2	2.6	1.8	2.5	2.2	2.5	2.2	-1.1	2.1
Angina	1.1	1.5	2.2	-1.2	-1.3	-1.3	-1.2	-1.3	-1.4	-1.3	-0.4	-1.3	-0.9	-1.5
Vitamin and mineral supplements	1.1	1.4	2.8	-1.2	-1.7	-1.6	-1.5	0.0	-1.2	-1.6	-0.5	-1.6	0.4	0.4
Impedance of leg (right)	1.1	5.2	7.4	-2.0	-2.1	-2.3	-2.7	-2.1	-2.5	-2.3	-2.3	-2.3	-1.4	-2.6
Alcohol usually taken with meals	1.1	1.8	3.4	-1.5	-1.5	-1.4	-0.9	-1.1	-1.5	-1.4	-0.8	-1.4	-1.2	-1.9
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	7.2	0.3	0.3	0.5	0.1	1.8	0.8	0.5	0.8	0.5	1.9	2.7
Birth weight of first child	1.1	2.0	3.8	0.7	1.4	1.3	1.4	1.7	1.4	1.3	1.9	1.3	1.1	1.5
High blood pressure (siblings)	1.1	1.5	2.3	-1.3	-1.3	-1.3	-0.9	-1.4	-1.5	-1.3	-0.1	-1.3	-0.8	-1.4
Medication: Allopurinol	1.1	1.5	3.7	1.6	1.2	1.3	0.8	0.8	1.3	1.3	1.9	1.3	0.4	0.7
Ever had bowel cancer screening	1.1	1.2	5.2	0.1	-0.5	-0.5	-0.2	-2.1	-0.6	-0.4	-0.2	-0.4	-2.3	-1.7
Pain experienced in last month	1.1	1.9	4.7	2.2	1.6	1.3	1.5	0.8	1.7	1.3	0.7	1.3	0.0	1.5
Medication: Metformin	1.0	1.5	2.4	-1.1	-1.5	-1.5	-1.4	-0.4	-1.5	-1.5	-0.7	-1.5	-0.5	-0.5
Supplements: Glucosamine	1.0	1.3	2.5	0.7	1.4	1.4	1.4	0.6	1.2	1.4	1.6	1.4	-0.5	0.1
Happiness	1.0	1.2	3.1	1.0	1.0	1.1	0.7	1.7	0.9	1.1	0.2	1.1	0.8	1.8
Number of full brothers	1.0	1.2	4.0	-1.1	-0.7	-1.0	-0.5	-1.5	-1.0	-1.0	0.6	-1.0	-2.0	-0.9
Eye problems/disorders: None of the above	1.0	1.2	2.1	-0.6	-1.3	-1.4	-0.8	0.1	-0.8	-1.5	0.9	-1.5	1.3	1.1
Emphysema/chronic bronchitis	1.0	1.1	1.8	0.6	1.1	1.3	0.8	0.8	1.1	1.3	0.8	1.3	1.3	0.5
Angina (self-reported)	1.0	1.3	3.0	-1.0	-0.9	-1.0	-1.2	-1.5	-1.2	-1.0	-0.3	-1.0	-1.2	-1.7
Had major operations	1.0	1.2	2.1	-1.4	-1.0	-0.9	-1.1	-1.4	-1.0	-0.9	-0.5	-0.9	-1.4	-1.0
Family relationship satisfaction	1.0	1.2	2.5	-1.6	-0.9	-0.8	-1.1	-0.8	-1.0	-0.8	-1.2	-0.8	-1.5	-1.0
Hypertension (Self-reported)	1.0	2.7	5.3	-2.3	-1.8	-2.0	-1.8	-0.9	-2.0	-2.0	-0.8	-2.0	-0.7	-0.8
Number of self-reported non-cancer illnesses	1.0	1.8	4.1	-1.4	-1.0	-1.1	-1.5	-2.0	-1.5	-1.1	-0.7	-1.1	-1.9	-0.7
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.3	0.5	1.4	1.5	1.5	0.4	1.4	1.5	1.0	1.5	-0.2	0.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.7	-0.8	-1.0	-1.2	-1.1	-0.6	-1.1	-1.2	-1.9	-1.2	0.1	-1.6
Neuroticism	0.9	2.1	3.3	-1.6	-1.4	-1.4	-1.7	-1.3	-1.7	-1.4	-0.6	-1.4	-0.7	-1.8
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	5.2	-1.0	-0.4	-0.6	-1.3	-1.2	-0.8	-0.6	-2.3	-0.6	-1.1	0.0
Ever had hysterectomy (womb removed)	0.9	1.0	4.9	-0.6	-0.6	-0.7	0.1	-1.2	-0.7	-0.6	-1.4	-0.6	-0.4	-2.2
Age when periods started (menarche)	0.9	2.3	7.5	0.9	1.6	1.4	0.2	1.7	1.5	1.4	0.6	1.4	1.8	2.7
Medication: Atenolol	0.9	1.1	3.8	0.8	0.4	0.4	0.3	-1.9	0.0	0.4	-0.2	0.4	-1.9	-1.8
Impedance of leg (left)	0.9	4.4	7.5	-1.7	-1.9	-2.1	-2.6	-1.7	-2.2	-2.1	-2.7	-2.1	-0.7	-2.2
Heart attack	0.9	1.1	3.0	-0.6	-0.9	-1.1	-1.0	-0.5	-1.0	-1.1	-1.7	-1.1	0.2	-1.7
Qualifications: A levels/AS levels or equivalent	0.9	2.0	6.2	-1.4	-1.4	-1.2	-0.8	-2.1	-1.5	-1.2	-0.0	-1.2	-2.5	-0.9
Breastfed as a baby	0.9	1.1	3.3	-1.2	-0.6	-0.6	-0.6	-1.5	-1.0	-0.6	-0.3	-0.6	-1.8	-1.6
Migraine (self-reported)	0.9	1.2	8.5	-0.5	-0.2	-0.4	-0.5	-1.4	-0.6	-0.4	-2.9	-0.4	-0.9	-0.1
Supplements: Vitamin C	0.9	1.1	2.2	0.4	1.5	1.4	1.0	0.6	1.3	1.4	0.5	1.4	0.5	0.3
Commuting to job workplace: Public transport	0.9	1.1	4.5	0.1	-0.2	-0.4	-1.2	-2.0	-0.7	-0.4	-0.3	-0.4	-2.1	-0.9
Alzheimer’s Disease (in mother)	0.8	0.9	4.3	-0.2	-0.3	-0.8	-0.3	0.3	-0.7	-0.8	-2.1	-0.8	1.6	-0.4
Blood White Count	0.8	5.9	13.0	0.9	3.6	3.3	2.5	0.8	3.0	3.3	-0.4	3.3	-0.1	1.4
Medication: Co-codamol	0.8	1.0	2.7	0.3	0.9	1.0	1.5	-0.8	0.7	1.0	0.8	1.0	-1.6	0.3
Qualifications: CSEs or equivalent	0.8	1.0	1.7	1.3	1.2	1.2	0.9	-0.2	0.8	1.2	0.8	1.2	-1.0	-0.3
Illnesses of siblings	0.8	1.2	2.9	1.3	0.9	1.1	0.6	1.1	1.3	1.1	-0.2	1.1	0.6	1.7
Father’s age at death	0.8	1.0	2.1	0.7	1.2	1.2	1.4	0.1	1.0	1.2	-0.1	1.2	-1.2	0.7
Illnesses of mother	0.8	1.0	4.1	0.6	0.2	-0.0	-0.3	1.7	0.7	-0.0	0.1	-0.0	2.0	1.7
Glaucoma (self-reported)	0.8	0.9	4.3	0.1	0.3	0.3	0.3	-1.2	-0.2	0.3	-1.0	0.3	-2.1	-1.6
Medication: Seretide 50 evohaler	0.8	0.9	2.5	-1.2	-0.9	-0.9	-1.6	-0.2	-1.0	-0.9	-1.2	-0.9	0.2	-0.6
Smoking status: Previous	0.8	1.1	2.0	1.0	1.3	1.3	0.5	1.3	1.4	1.3	-0.3	1.3	0.9	0.3
Commuting to job workplace: Walk	0.8	0.8	2.3	-0.3	-1.1	-1.0	-0.9	-0.7	-1.0	-1.0	-0.6	-1.0	-0.1	-1.5
Eye problems/disorders: Glaucoma	0.8	1.0	5.2	0.0	0.3	0.5	0.5	-1.2	-0.2	0.5	-0.5	0.5	-2.3	-1.6
Irritability	0.8	1.3	2.2	0.5	1.5	1.4	1.2	1.1	1.2	1.4	1.0	1.4	1.0	-0.1
Ever depressed for a whole week	0.8	1.0	2.8	0.8	1.1	0.9	0.8	1.4	0.9	0.9	1.7	0.9	0.6	0.8
Alzheimer’s Disease (including proxy)	0.7	1.1	4.0	-0.1	-0.6	-1.1	-1.1	-0.9	-1.0	-1.1	-2.0	-1.1	1.0	-0.0
Crohns Disease (2017)	0.7	1.5	5.3	0.8	0.8	0.7	0.7	2.0	1.0	0.7	1.7	0.7	2.3	0.8
Breast Cancer	0.7	1.7	3.2	1.8	1.3	1.4	1.1	1.0	1.7	1.4	1.1	1.4	1.1	0.5
Relative age of first facial hair	0.7	1.4	2.7	-0.9	-1.5	-1.5	-1.7	-0.4	-1.4	-1.5	0.1	-1.5	0.1	0.7
Leg fat-free mass (left)	0.7	3.4	11.6	0.6	0.7	1.0	0.9	2.9	1.2	1.0	2.5	1.0	2.3	3.4
Trunk fat percentage	0.7	2.7	10.5	0.2	0.5	0.7	-0.3	3.2	0.8	0.7	1.2	0.7	2.5	3.0
Stomach or abdominal pain in last month	0.7	0.9	3.5	-0.9	-0.8	-0.7	-0.4	-0.9	-0.8	-0.7	-0.9	-0.7	-0.9	-1.9
Medication: Levothyroxine sodium	0.7	1.3	4.4	-1.0	-1.1	-0.7	-1.1	-1.6	-1.0	-0.7	0.6	-0.7	-2.1	-0.8
Trunk fat mass	0.7	3.0	10.9	0.1	0.5	0.6	-0.3	3.3	0.7	0.6	1.7	0.6	2.5	3.3
Hair/balding pattern: Pattern 3	0.7	1.0	2.0	1.2	1.2	1.2	1.4	0.7	1.2	1.2	0.2	1.2	-0.2	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.9	2.8	-0.7	-0.4	-0.5	-0.6	-1.4	-0.8	-0.5	-0.2	-0.5	-1.7	-1.4
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.1	-1.5	-0.8	-0.7	-0.8	-0.9	-0.5	-0.7	-1.3	-0.7	-0.7	-1.3
Medication: Paracetamol	0.7	1.1	2.0	-1.4	-1.0	-1.1	-1.2	-0.6	-1.2	-1.1	-1.2	-1.1	-0.8	-0.2
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.7	1.3	0.8	1.0	0.5	-0.4	0.6	1.0	1.2	1.0	-0.9	-0.7
Health satisfaction	0.7	1.0	1.4	1.1	1.1	1.2	1.2	1.1	0.9	1.2	0.3	1.2	0.1	0.6
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.5	1.1	1.2	1.1	0.8	0.7	1.2	1.1	-0.1	1.1	0.4	0.2
Medication: Ibuprofen	0.7	0.9	5.3	-0.0	-0.0	0.1	-0.3	1.1	0.3	0.1	1.0	0.1	1.4	2.3
Leg fat-free mass (right)	0.7	4.0	12.2	0.9	0.9	1.2	1.2	3.1	1.4	1.2	2.3	1.2	2.6	3.5
Leg predicted mass (right)	0.7	3.9	11.7	0.8	0.9	1.2	1.1	3.1	1.4	1.2	2.3	1.2	2.7	3.4
Schizophrenia vs Biploar Disorder	0.6	0.8	2.8	0.4	-0.0	0.1	0.6	1.6	0.4	0.0	1.4	0.0	1.7	0.9
Coronary Artery Disease (CAD)	0.6	0.7	2.0	1.3	0.4	0.6	0.6	1.1	0.6	0.0	-0.2	0.0	1.4	1.4
Systolic Blood Pressure	0.6	2.8	5.2	-2.3	-1.9	-2.0	-1.6	-1.2	-1.8	-2.0	-1.3	-2.0	-0.6	-1.1
Chronotype (morning person)	0.6	1.5	3.3	-1.8	-1.2	-1.0	-1.1	-1.4	-1.2	-0.9	0.9	-0.9	-0.8	-1.7
Number of treatments/medications taken	0.6	1.0	2.6	-1.6	-0.7	-0.8	-1.1	-1.3	-1.0	-0.8	-0.8	-0.8	-1.4	0.0
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.1	-0.8	-1.4	-1.3	-1.4	-1.2	-1.4	-1.3	0.1	-1.3	-0.9	-1.0
Leg predicted mass (left)	0.6	3.4	11.3	0.6	0.7	1.0	0.9	2.9	1.1	1.0	2.4	1.0	2.4	3.4
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.3	0.6	1.0	1.2	0.3	0.5	1.0	1.2	1.1	1.2	1.5	0.1
Had other major operations	0.6	0.7	1.5	0.7	0.9	1.0	1.2	0.3	1.2	1.0	0.6	1.0	-0.2	0.2
Mouth/teeth dental problems	0.6	1.0	2.6	1.3	0.6	0.7	0.1	1.0	0.6	0.7	1.6	0.7	0.9	1.6
Pain all over the body in last month	0.6	0.7	2.7	-0.7	0.4	0.1	-0.6	1.1	0.3	0.1	-0.3	0.1	1.5	1.7
Medication: Cholesterol lowering	0.6	1.0	4.3	0.6	0.1	0.1	0.3	-1.6	0.2	0.1	-0.7	0.1	-2.1	-1.8
Arm fat mass (right)	0.6	2.5	9.5	0.1	0.4	0.6	-0.0	2.7	0.6	0.6	2.1	0.6	2.1	3.1
Tense / ‘highly strung’	0.6	1.1	1.8	-1.0	-1.1	-1.0	-1.1	-0.7	-1.1	-1.0	-1.4	-1.0	-0.4	-1.0
Pulse wave peak to peak time	0.6	0.7	1.4	0.5	-1.1	-1.2	-0.4	0.3	-0.9	-1.2	-0.4	-1.2	1.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	2.7	-0.3	-1.1	-1.4	-0.3	-1.1	-1.1	-1.4	-0.5	-1.4	-1.6	-1.1
Arm fat mass (left)	0.6	2.3	8.6	0.1	0.4	0.6	0.0	2.7	0.7	0.6	2.0	0.6	2.1	2.9
Mother’s age at death	0.6	0.8	1.8	-1.2	-1.3	-1.0	-0.8	-0.0	-1.0	-1.0	0.1	-1.0	-0.3	-0.5
Number of operations (self-reported)	0.6	0.9	2.3	-0.6	-0.7	-0.7	-0.5	-1.2	-0.7	-0.7	-1.4	-0.7	-1.1	-1.5
Myopia	0.6	0.9	2.6	1.2	0.4	0.6	1.6	-1.4	0.3	0.6	0.3	0.6	-1.2	-1.2
Neuroticism (Nagel 2018)	0.5	1.2	3.4	-1.8	-0.9	-0.9	-1.2	-1.0	-1.2	-0.8	-0.0	-0.8	-0.2	-1.7
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.3	-0.7	-1.1	-1.1	-0.7	-1.2	-1.2	-1.1	0.4	-1.1	-1.5	-1.1
Body Mass Index (BMI) (2010)	0.5	0.7	1.5	-1.2	-0.9	-0.8	-0.9	-0.9	-0.8	-0.8	-1.0	-0.8	-0.5	-0.5
Triglycerides	0.5	0.8	3.0	-0.6	-0.8	-0.6	-0.4	-1.7	-0.6	-0.6	-0.3	-0.6	-1.6	-0.6
BMI	0.5	2.7	6.6	0.6	1.2	1.4	0.7	2.6	1.4	1.4	2.0	1.4	1.8	2.4
Cardiovascular Disease	0.5	1.7	3.2	-1.8	-1.2	-1.4	-1.3	-1.3	-1.5	-1.3	-1.0	-1.3	-0.7	-1.2
Fed-up feelings	0.5	0.9	3.4	0.3	0.7	0.7	0.0	1.5	0.6	0.7	0.9	0.7	1.9	1.1
High blood pressure	0.5	1.3	2.6	-1.6	-1.2	-1.4	-1.2	-0.6	-1.5	-1.4	-0.4	-1.4	-0.5	-0.6
Neuroticism score	0.5	1.1	2.6	-1.2	-1.0	-0.8	-1.4	-1.2	-1.1	-0.8	-0.1	-0.8	-0.8	-1.6
Weight	0.5	2.4	9.6	0.0	0.3	0.5	-0.0	2.6	0.5	0.5	2.2	0.5	2.0	3.1
Arm fat percentage (right)	0.5	1.8	7.4	-0.2	0.1	0.4	-0.4	2.5	0.4	0.4	1.7	0.4	1.7	2.7
Hip circumference	0.5	2.3	6.2	0.3	1.1	1.3	0.6	2.4	1.3	1.2	1.8	1.2	1.6	2.5
Hair/balding pattern: Pattern 4	0.5	1.3	1.9	-1.3	-1.3	-1.1	-1.2	-1.1	-1.1	-1.1	-0.3	-1.1	-1.4	-1.1
Peak expiratory flow (PEF)	0.5	1.2	2.5	-0.0	-1.3	-1.6	-1.4	0.1	-1.1	-1.6	-0.4	-1.6	0.2	0.6
Forced vital capacity (FVC), Best measure	0.5	1.9	3.5	-1.1	-1.9	-1.9	-0.8	-0.4	-1.6	-1.9	-1.2	-1.9	0.8	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.9	-1.1	-0.5	-0.5	-0.6	-1.4	-0.9	-0.5	0.5	-0.5	-1.3	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.1	1.0	0.8	0.7	0.8	1.0	0.6	0.7	-0.1	0.7	1.0	-0.2
Whole body fat mass	0.5	2.0	7.5	-0.2	0.1	0.2	-0.6	2.6	0.2	0.2	1.6	0.2	2.0	2.7
Chest pain or discomfort	0.5	0.7	2.8	-1.7	-0.6	-0.8	-0.9	0.3	-0.6	-0.7	-0.7	-0.7	0.7	-0.4
Leg pain on walking	0.5	0.6	2.3	-0.8	0.6	0.6	1.0	0.0	0.7	0.6	-0.5	0.6	-0.5	1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	5.9	0.0	-0.4	-0.3	-0.7	1.8	0.0	-0.3	-0.1	-0.3	1.4	2.4
Arm fat percentage (left)	0.5	2.0	7.3	0.1	0.4	0.6	-0.1	2.7	0.6	0.6	1.6	0.6	1.9	2.7
Medication: Paracetamol	0.5	0.8	2.4	-1.6	-0.9	-1.0	-1.0	-0.1	-1.0	-1.0	-0.8	-1.0	-0.0	0.7
Vascular/heart problems diagnosed by doctor	0.5	1.3	2.1	1.4	1.2	1.4	1.2	0.7	1.4	1.4	0.7	1.4	0.4	0.8
Cholesterol lowering medication	0.5	0.8	1.4	-0.4	-1.0	-1.1	-0.9	-0.7	-1.2	-1.1	-0.9	-1.1	-0.2	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.8	1.3	0.8	0.6	1.3	-0.2	0.5	0.6	-0.8	0.6	0.8	-0.7
Bipolar Disorder (2018)	0.4	0.6	1.3	0.6	0.8	1.0	0.6	-0.1	0.8	1.0	-1.2	1.0	-0.5	-0.6
Crohns Disease (2012)	0.4	0.6	3.1	0.9	0.0	-0.1	0.1	1.3	0.2	-0.1	0.3	-0.1	1.8	0.9
HbA1C	0.4	0.4	0.8	0.7	0.7	0.6	0.5	0.6	0.5	0.6	0.9	0.6	0.8	0.6
HDL Cholesterol	0.4	0.6	2.5	0.6	0.9	0.7	1.6	0.1	0.4	0.7	-0.1	0.7	-0.4	-1.2
Respiratory disease	0.4	0.8	2.9	0.3	0.8	0.6	0.0	1.5	0.3	0.6	0.9	0.6	1.7	1.1
Average weekly fortified wine intake	0.4	0.4	1.0	0.4	0.8	0.8	1.0	-0.1	0.9	0.8	-0.3	0.8	0.1	0.7
Maternal smoking around birth	0.4	0.6	1.1	0.9	0.9	0.8	0.4	0.7	1.1	0.8	-0.2	0.8	0.5	0.7
Body mass index (BMI)	0.4	1.5	4.2	0.5	0.7	0.9	0.4	1.8	0.8	0.9	2.1	0.9	1.0	2.1
Medication: Lansoprazole	0.4	0.4	2.1	0.0	-0.0	-0.1	0.5	-1.2	-0.3	-0.1	-0.5	-0.1	-1.5	-0.8
Pulse wave Arterial Stiffness index	0.4	0.4	0.7	-0.8	0.8	0.8	0.1	-0.3	0.6	0.8	0.1	0.8	-0.9	-0.2
Length of working week for main job	0.4	0.5	1.3	0.9	0.6	0.7	0.7	0.0	0.7	0.7	-0.3	0.7	-0.5	1.1
Loud music exposure frequency	0.4	0.5	3.1	0.2	0.2	0.3	0.3	-1.0	-0.0	0.3	0.7	0.3	-1.8	-0.4
Blood clot in the leg (DVT)	0.4	0.5	1.3	1.1	0.4	0.3	1.1	-0.3	0.2	0.3	-0.9	0.3	0.7	-0.8
Headache pain in last month	0.4	0.7	2.1	-0.3	-0.4	-0.2	-0.5	-1.4	-0.7	-0.2	-0.7	-0.2	-1.3	-1.4
Body fat percentage	0.4	1.4	5.5	-0.4	-0.1	0.1	-0.8	2.3	0.1	0.1	1.0	0.1	1.7	2.3
Illnesses of siblings: Diabetes	0.4	0.5	3.1	-0.1	0.6	0.4	0.7	0.5	0.5	0.4	0.4	0.4	1.8	0.9
Whole body fat-free mass	0.4	2.1	7.2	0.4	0.5	0.7	0.8	2.4	0.8	0.7	2.0	0.7	1.9	2.7
Mood swings	0.4	0.6	1.7	0.5	0.8	0.8	-0.0	0.8	0.5	0.8	1.3	0.8	1.3	-0.3
Diabetes diagnosed by doctor	0.4	0.6	1.6	-0.8	-0.8	-0.8	-1.2	-0.1	-0.7	-0.8	-0.9	-0.8	-0.4	0.4
Back pain experienced in last month	0.4	0.6	2.2	-0.9	-0.3	-0.2	-0.2	1.1	-0.2	-0.2	-1.1	-0.2	1.5	1.1
Asthma (self-reported)	0.4	0.8	1.7	0.3	1.0	0.9	0.4	1.3	0.7	0.9	0.4	0.9	1.3	1.2
Whole body water mass	0.4	2.2	7.1	0.4	0.6	0.8	0.8	2.4	0.9	0.7	2.0	0.7	1.9	2.7
Financial situation satisfaction	0.4	0.4	1.7	0.5	0.1	0.0	0.1	1.3	-0.1	0.0	-0.0	0.0	1.1	1.3
Medication: Blood pressure	0.4	0.7	1.1	-0.7	-0.7	-0.8	-0.4	-1.1	-1.0	-0.8	0.7	-0.8	-0.9	-1.0
Basal metabolic rate	0.4	2.5	8.6	0.4	0.5	0.7	0.7	2.5	0.8	0.7	2.2	0.7	2.1	2.9
Risk taking	0.4	0.6	3.6	-0.9	-0.2	-0.5	0.1	-0.2	-0.7	-0.5	-1.9	-0.5	-0.5	-1.0
Alcohol drinker status: Previous	0.4	0.4	1.1	0.5	0.5	0.6	0.1	-1.0	0.5	0.6	0.8	0.6	-1.0	-0.2
Pack years of smoking	0.4	0.6	1.9	-0.3	-0.6	-0.6	-1.0	-1.1	-0.8	-0.6	-0.0	-0.6	-0.4	-1.4
Impedance of whole body	0.4	2.0	5.2	-1.3	-1.3	-1.4	-2.1	-0.4	-1.4	-1.4	-2.3	-1.4	0.2	-0.9
Alzheimer’s Disease (in father)	0.3	0.3	0.9	0.8	0.6	0.5	-0.3	-0.2	0.3	0.5	0.3	0.5	0.4	1.0
Height	0.3	5.2	13.3	-2.6	-1.7	-1.6	-1.4	3.6	-1.0	-1.6	0.7	-1.6	3.1	3.6
Allergy or Eczema	0.3	0.7	1.3	0.2	-0.8	-0.8	-0.7	-1.1	-0.7	-0.8	1.0	-0.8	-0.9	-1.0
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.1	-0.7	-0.7	-0.8	-1.1	-0.7	-0.8	-0.8	-0.4	-0.8	-0.9	0.2
Systolic blood pressure, automated reading	0.3	1.0	1.6	-1.2	-1.3	-1.2	-0.9	0.5	-1.0	-1.2	-0.9	-1.2	0.6	0.1
Severe depression (siblings)	0.3	0.4	2.1	-0.2	0.4	0.6	-0.0	0.1	0.5	0.6	1.4	0.6	-0.2	0.4
Pack years adult smoking proportion	0.3	0.5	1.1	-0.3	-0.6	-0.6	-1.0	-0.9	-0.7	-0.6	0.1	-0.6	-0.3	-1.1
Relative age voice broke	0.3	0.4	2.9	0.1	-0.0	-0.0	0.3	0.9	0.0	-0.0	0.8	-0.0	0.6	1.7
Waist circumference	0.3	0.9	2.7	-1.1	-0.9	-0.8	-1.4	-0.0	-1.1	-0.8	0.7	-0.8	-0.2	1.6
Forced vital capacity (FVC)	0.3	1.3	2.5	-0.8	-1.5	-1.6	-0.7	0.3	-1.2	-1.6	-1.1	-1.6	1.0	0.5
Alcohol intake versus 10 years previously	0.3	0.4	1.5	0.7	0.4	0.2	-0.1	-1.0	0.0	0.2	1.2	0.2	-1.1	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.4	1.2	0.8	0.9	0.6	0.2	0.7	0.9	0.2	0.9	0.3	0.7
Falls in the last year	0.3	0.4	0.9	0.1	0.8	0.9	0.3	-0.3	0.5	0.9	0.2	0.9	-0.3	-0.6
Asthma	0.3	0.6	1.5	0.2	0.8	0.7	0.2	1.2	0.5	0.7	0.4	0.7	1.2	1.2
Exposure to tobacco smoke outside home	0.3	0.4	1.5	0.5	0.7	0.7	0.5	0.0	0.6	0.7	0.2	0.7	-0.0	-1.2
Worry too long after embarrassment	0.3	0.5	1.6	-0.7	-0.5	-0.2	0.3	-1.0	-0.4	-0.2	-0.7	-0.2	-1.1	-1.3
Shortness of breath walking on level ground	0.3	0.4	1.1	0.7	0.7	0.7	0.6	0.0	0.3	0.7	1.0	0.7	0.3	-0.5
Medication for pain relief, constipation, heartburn	0.3	0.5	1.5	1.0	0.6	0.6	0.7	0.4	0.6	0.6	1.2	0.6	0.4	-0.0
Leg fat mass (right)	0.3	1.0	2.7	-0.7	-0.6	-0.4	-1.1	1.4	-0.5	-0.4	1.6	-0.4	0.8	1.7
Arm predicted mass (right)	0.3	1.4	3.9	0.7	0.5	0.6	0.7	1.9	0.8	0.6	1.4	0.6	1.8	2.0
Alcohol intake frequency.	0.3	0.8	2.9	-0.9	-0.3	-0.3	-0.7	-1.6	-0.5	-0.3	1.7	-0.3	-0.6	-0.8
Number of full sisters	0.3	0.3	1.6	-0.9	-0.3	-0.1	-0.1	-1.3	-0.4	-0.1	0.1	-0.1	-0.6	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.5	1.2	0.3	0.4	0.9	-0.7	0.3	0.4	-0.0	0.4	-0.5	-0.2
Illnesses of father: Heart disease	0.3	0.5	1.4	-0.3	-0.9	-0.8	0.3	0.1	-0.5	-0.8	-1.2	-0.8	-0.6	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.9	-0.4	-0.9	-0.8	-0.2	-0.6	-0.6	-0.8	-0.9	-0.8	-0.6	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.7	-0.3	-0.5	-0.7	-0.4	-0.9	-0.6	-0.7	-0.8	-0.7	-0.3	0.8
Osteoporosis (self-reported)	0.3	0.4	0.8	0.1	0.7	0.9	-0.4	0.4	0.9	0.9	0.1	0.9	-0.4	-0.1
Medication: Gliclazide	0.3	0.3	1.2	0.2	-0.2	-0.3	-0.7	-1.1	-0.2	-0.3	-0.8	-0.3	-1.0	0.2
Medication: Bendroflumethiazide	0.3	0.4	1.0	0.5	0.3	0.5	0.3	1.0	0.5	0.5	0.5	0.5	1.0	0.9
Medication: Lisinopril	0.3	0.4	1.3	-0.3	-0.4	-0.3	-0.3	-1.1	-0.5	-0.3	0.3	-0.3	-1.1	-0.8
Leg fat mass (left)	0.3	1.0	3.6	-0.6	-0.5	-0.4	-1.1	1.5	-0.4	-0.4	1.4	-0.4	1.0	1.9
Major Depression (MDD)	0.2	0.2	1.1	-0.2	-0.3	-0.3	-1.0	0.1	-0.2	-0.3	-0.7	-0.3	-0.1	0.4
Primary Biliary Cirrhosis	0.2	0.3	1.1	-0.1	-0.4	-0.4	0.3	0.9	0.0	-0.4	-0.6	-0.4	0.5	1.0
Lung FVC	0.2	0.9	2.0	-0.5	-0.8	-1.1	-0.1	-1.3	-0.9	-1.1	-1.4	-1.1	0.3	-1.0
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.0	0.4	0.1	-0.0	0.5	-0.1	0.0	-0.0	-0.4	-0.0	1.0	0.7
Serious illness, injury or assault to yourself	0.2	0.2	1.2	-0.2	0.4	0.2	0.0	-0.2	-0.2	0.2	-0.7	0.2	-0.1	-1.1
Multivitamins +/- minerals	0.2	0.2	0.4	0.6	0.5	0.4	0.5	-0.2	0.1	0.4	-0.6	0.4	-0.7	-0.5
Sitting height	0.2	1.5	6.5	0.3	0.4	0.4	0.5	2.4	0.6	0.4	0.4	0.4	2.5	1.8
Chronic bronchitis/emphysema (father)	0.2	0.2	0.7	-0.1	-0.5	-0.4	-0.8	0.5	-0.4	-0.4	0.3	-0.4	0.3	-0.7
Hearing difficulty/problems with background noise	0.2	0.3	1.5	0.2	0.3	0.5	-0.1	-0.5	0.4	0.5	-1.2	0.5	-0.0	-0.8
Hair/balding pattern: Pattern 2	0.2	0.3	1.1	-1.1	-0.5	-0.4	-0.5	0.1	-0.5	-0.4	-0.5	-0.4	0.2	0.2
Had menopause	0.2	0.2	1.6	0.2	-0.2	-0.1	-0.2	0.5	-0.2	-0.1	-1.2	-0.1	0.5	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.7	0.1	-0.8	-0.6	-0.7	-0.6	-0.7	-0.6	-0.2	-0.6	-0.3	-0.8
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.1	-0.9	-0.3	-0.5	-1.0	0.0	-0.6	-0.4	0.0	-0.4	0.0	0.5
Qualifications: None of the above	0.2	0.4	2.6	-0.3	0.2	-0.1	-0.1	1.2	0.2	-0.1	-0.0	-0.1	1.6	0.4
Diabetes (self-reported)	0.2	0.4	1.2	-0.8	-0.6	-0.6	-1.1	0.3	-0.5	-0.6	-0.1	-0.6	-0.3	0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.0	-0.2	-0.3	-0.2	0.3	-0.3	-0.3	-0.2	1.4	-0.2	-0.4	0.2
Fluid intelligence score	0.2	0.5	2.9	-0.0	-0.2	-0.1	-0.2	-0.4	-0.2	-0.1	0.3	-0.1	-1.3	-1.7
Impedance of arm (right)	0.2	0.7	2.2	-1.0	-0.8	-0.7	-1.5	0.6	-0.7	-0.7	-0.9	-0.7	0.8	0.3
Trunk fat-free mass	0.2	1.4	4.6	0.2	0.3	0.4	0.6	1.9	0.5	0.4	1.8	0.4	1.5	2.1
Number of live births	0.2	0.3	1.6	0.3	0.1	0.1	1.3	0.2	0.1	0.1	-0.8	0.1	0.6	-0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.6	0.3	-0.9	-1.1	-0.2	0.7	-0.7	-1.1	-0.6	-1.1	0.8	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.0	0.4	-0.8	-0.9	0.1	0.6	-0.5	-1.0	-0.5	-1.0	0.8	1.0
Trunk predicted mass	0.2	1.4	4.7	0.2	0.3	0.5	0.6	1.9	0.5	0.4	1.8	0.4	1.6	2.2
Standing height	0.2	2.1	7.0	-1.1	-0.9	-0.8	-1.0	2.3	-0.6	-0.8	0.4	-0.8	2.4	2.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.1	-0.4	-0.4	-0.4	-0.4	0.4	-0.5	-0.4	0.9	-0.4	1.0	0.8
Medication: Amlodipine	0.2	0.2	1.9	-0.1	0.1	0.1	0.3	0.7	0.1	0.1	1.4	0.1	0.3	0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.7	-0.4	-0.1	-0.1	-0.3	-0.5	-0.5	-0.1	-1.3	-0.1	0.3	0.2
Leg fat percentage (right)	0.2	0.8	2.3	-1.0	-0.8	-0.8	-1.5	0.6	-0.9	-0.8	1.1	-0.8	-0.1	0.9
Arm fat-free mass (right)	0.2	1.1	4.0	0.3	0.3	0.4	0.5	1.8	0.5	0.4	1.3	0.4	1.5	2.0
Medication: Blood pressure	0.2	0.3	1.9	-0.8	-0.0	-0.2	-0.5	0.3	-0.2	-0.2	-1.4	-0.2	-0.4	-0.1
Mean time to correctly identify matches	0.2	0.5	4.1	-0.6	0.1	0.1	-0.3	0.1	-0.2	0.2	2.0	0.2	-0.4	-0.5
Heart disease (mother)	0.2	0.2	1.1	-0.1	-0.2	-0.1	0.1	-0.6	-0.2	-0.1	0.1	-0.1	-0.5	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	-0.1	-0.3	-0.5	-0.5	0.5	-0.6	-0.5	-0.3	-0.5	0.8	-0.1
Age at last live birth	0.2	0.3	0.7	0.7	0.6	0.5	0.5	-0.6	0.5	0.5	0.0	0.5	-0.8	-0.3
Loneliness, isolation	0.2	0.3	1.5	-0.6	-0.4	-0.2	-0.5	-1.2	-0.5	-0.2	0.6	-0.2	-0.8	0.4
Long-standing illness, disability or infirmity	0.2	0.3	0.9	-0.0	0.4	0.3	-0.5	-1.0	0.4	0.3	-0.4	0.3	-0.9	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.1	-0.2	-0.1	0.0	-0.4	0.3	0.2	0.0	-1.1	0.0	0.9	0.3
Eye problems/disorders: Cataract	0.2	0.2	0.5	-0.5	0.4	0.6	-0.2	-0.1	0.1	0.7	-0.7	0.7	-0.4	-0.4
Medication for cholesterol	0.2	0.3	1.1	0.3	0.3	0.5	0.4	1.1	0.7	0.5	-0.1	0.5	0.8	-0.3
Breast cancer (self-reported)	0.2	0.2	0.8	-0.0	-0.2	-0.1	-0.4	0.7	0.3	-0.1	-0.1	-0.1	0.8	0.9
Osteoarthritis (self-reported)	0.2	0.3	0.6	0.1	0.8	0.6	0.6	0.7	0.6	0.6	0.1	0.6	0.0	0.3
Hearing aid user	0.2	0.2	0.5	-0.2	-0.7	-0.6	-0.4	-0.2	-0.5	-0.6	0.0	-0.6	-0.2	-0.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.7	0.3	-0.8	-0.6	-0.8	0.2	-0.2	-0.7	0.0	-0.7	0.5	0.2
High cholesterol (Self-reported)	0.2	0.3	0.9	0.5	0.6	0.5	0.3	-0.6	0.5	0.5	0.3	0.5	-0.9	-0.3
Medication: Atorvastatin	0.2	0.2	0.7	0.3	0.0	0.1	0.4	0.7	0.2	0.1	0.6	0.1	0.3	0.9
Illnesses of father: High blood pressure	0.2	0.3	0.7	-0.2	0.6	0.5	0.6	-0.4	0.0	0.5	0.0	0.5	-0.8	-0.7
Leg fat percentage (left)	0.2	0.7	1.8	-0.7	-0.6	-0.6	-1.3	0.9	-0.7	-0.6	0.9	-0.6	0.3	1.3
Arm fat-free mass (left)	0.2	1.1	4.8	0.1	0.2	0.3	0.3	1.9	0.4	0.3	1.3	0.3	1.5	2.2
Unable to work because of sickness or disability	0.2	0.3	1.5	-0.1	0.3	0.0	-0.3	0.4	0.1	0.0	-0.7	0.0	1.2	0.7
Supplements: Calcium	0.2	0.2	0.5	0.2	0.4	0.6	0.0	-0.3	0.2	0.6	-0.1	0.6	-0.7	0.1
Basal cell carcinoma (self-reported)	0.2	0.2	1.6	-0.4	-0.1	-0.1	-0.5	-0.2	-0.1	-0.1	-1.3	-0.1	-0.1	0.6
Arm predicted mass (left)	0.2	1.1	4.7	0.2	0.1	0.3	0.3	1.7	0.3	0.2	1.3	0.2	1.4	2.2
Bipolar Disorder or Schizophrenia	0.1	0.3	1.0	0.5	0.5	0.6	0.1	0.2	0.6	0.6	-1.0	0.6	0.0	-0.6
Depressed Affect (Nagel 2018)	0.1	0.3	1.4	-0.3	0.3	0.4	-0.4	0.1	0.1	0.4	1.2	0.4	1.0	-0.5
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.6	-0.3	-0.4	-0.3	-0.8	-1.0	-0.5	-0.3	0.7	-0.3	-1.3	-0.5
Reaction Time	0.1	0.3	2.2	-0.4	-0.1	0.1	-0.4	0.3	-0.3	0.1	1.5	0.1	-0.1	-0.5
Ovarian Cancer	0.1	0.1	0.4	-0.0	0.2	0.2	0.2	0.0	0.1	0.2	-0.7	0.2	0.4	0.2
Age at First Birth	0.1	0.1	0.4	0.3	0.0	0.3	0.2	0.1	0.3	0.4	0.5	0.4	0.6	-0.3
Lupus	0.1	0.2	0.6	0.5	-0.0	-0.2	0.3	0.2	-0.1	-0.2	0.8	-0.2	-0.7	0.5
Neuroticism (2016)	0.1	0.1	0.6	0.2	-0.1	-0.1	0.3	-0.8	-0.3	-0.1	0.5	-0.1	0.2	-0.4
Schizophrenia (2014)	0.1	0.2	1.0	1.0	0.3	0.4	0.3	0.2	0.5	0.0	-0.1	0.0	0.0	-1.0
Blood Platelet Count	0.1	1.7	5.1	0.5	-1.1	-0.8	-1.5	-2.2	-0.9	-0.8	1.2	-0.8	-0.9	-2.2
Blood Red Count	0.1	1.0	2.8	-1.7	0.0	-0.1	0.2	-1.4	-0.2	-0.1	-1.6	-0.1	-1.5	-0.8
Heel T-Score	0.1	0.4	2.8	-0.2	0.2	0.4	-0.0	1.7	0.2	0.4	0.1	0.4	1.0	-0.1
Hair Pigment	0.1	1.7	5.0	1.5	1.6	1.4	1.0	-0.4	1.4	1.4	2.2	1.4	-0.2	0.6
Tanning	0.1	1.1	2.6	1.2	1.2	1.2	1.6	0.2	1.1	1.3	0.8	1.3	-0.6	0.4
Hand grip strength (left)	0.1	0.2	0.7	-0.0	0.2	0.3	-0.3	0.5	0.5	0.3	0.4	0.3	0.2	0.8
Average weekly spirits intake	0.1	0.1	0.6	0.2	0.1	0.1	-0.6	0.3	0.2	0.1	0.5	0.1	0.8	0.1
High blood pressure (mother)	0.1	0.2	0.6	-0.6	-0.3	0.0	0.6	-0.8	-0.4	0.0	0.5	0.0	-0.5	-0.6
Allergy	0.1	0.1	0.3	0.1	0.3	0.4	0.6	0.1	0.5	0.3	-0.5	0.3	-0.5	0.2
Noisy workplace	0.1	0.1	0.7	-0.1	-0.3	-0.3	-0.8	-0.4	-0.1	-0.3	-0.4	-0.3	0.0	-0.2
Impedance of arm (left)	0.1	0.5	1.3	-0.7	-0.5	-0.5	-0.9	1.0	-0.4	-0.5	-1.0	-0.5	1.1	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.5	-0.4	-0.3	-0.1	0.3	-0.5	-0.4	-0.1	0.4	-0.1	-0.7	-0.1
Age at first live birth	0.1	0.1	0.2	0.1	-0.3	-0.4	-0.5	0.4	-0.3	-0.4	0.5	-0.4	0.2	0.2
Neck or shoulder pain in last month	0.1	0.1	0.7	-0.3	0.1	0.0	0.4	-0.1	-0.2	0.0	-0.2	0.0	0.4	-0.9
Medication: Omeprazole	0.1	0.2	0.7	0.0	0.1	0.0	-0.2	-0.8	-0.1	0.0	-0.5	0.0	-0.9	0.1
Comparative height size at age 10	0.1	0.6	2.0	0.4	0.2	0.1	0.9	1.4	0.2	0.1	0.7	0.1	1.0	1.4
Overall health rating	0.1	0.2	1.1	-0.2	0.6	0.5	-0.3	0.2	0.4	0.5	-1.0	0.5	0.0	0.1
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.6	-0.8	-0.2	0.1	0.5	-0.2	0.2	0.1	0.2	0.1	-0.7	0.2
Knee pain experienced in last month	0.1	0.2	0.8	-0.6	-0.1	-0.0	0.9	0.2	-0.1	-0.0	0.8	-0.0	-0.3	0.3
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.6	-0.8	-0.5	-0.1	0.3	0.2	0.1	-0.1	-0.3	-0.1	0.1	0.8
Friendships satisfaction	0.1	0.1	0.2	0.2	0.4	0.5	0.0	-0.1	0.3	0.4	-0.1	0.4	-0.4	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.2	0.4	0.4	0.4	-0.1	0.4	0.4	0.3	0.4	0.4	0.4
Miserableness	0.1	0.1	0.9	-0.6	0.1	-0.0	-0.1	0.3	-0.2	-0.0	0.3	-0.0	0.9	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.7	-0.5	-0.1	-0.0	0.8	0.6	0.2	-0.0	0.3	-0.0	0.6	0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.8	0.1	-0.0	-0.2	-0.1	-0.2	-0.0	-0.2	-0.2	-0.2	-0.3	0.9
Schizophrenia (2018)	0.0	0.1	0.2	0.1	-0.1	-0.0	-0.4	0.3	0.1	-0.0	-0.3	-0.0	0.4	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hand grip strength (right)	0.0	0.1	0.2	0.3	0.1	0.3	-0.2	0.4	0.4	0.3	-0.1	0.3	0.1	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.4	0.5	-0.6	-0.2	0.0	0.2	-0.0	-0.2	0.7	-0.2	0.3	-0.1

Hub : Genes

MAP3K10

Models

Trait associations