TWAS hub - VSNL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0460	0.0200	0.00520	-0.002	0.016	-0.001	0.014	-0.002	0.670	0.0041	0.390	0.0061	0.91000
2	TCGA	Lung Squamous Cell Carcinoma	0.0584	0.0281	0.00025	0.012	0.022	0.013	NA	0.027	0.013	0.0014	0.012	NA	0.00038
3	TCGA	Pancreatic Adenocarcinoma	0.0860	0.0490	0.00850	0.027	0.039	-0.004	NA	0.011	0.026	0.0092	0.510	NA	0.11000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate	4.7	7.9	21.3	4.6	0.5	1.4
Diabetes (father)	4.6	5.7	9.7	0.2	-2.7	3.1
Eye problems/disorders: Diabetes related eye disease	4.5	4.9	8.6	2.3	-1.0	2.9
Medication: Seretide 50 evohaler	4.5	5.2	14.8	3.8	0.9	-0.2
Pulse rate, automated reading	4.3	14.1	40.2	6.3	0.6	-1.3
Time employed in main current job	4.1	4.7	13.8	-3.7	0.3	0.6
Serious illness, injury or assault to yourself	3.8	4.6	8.6	2.0	1.0	2.9
Financial situation satisfaction	3.7	4.6	10.0	3.2	1.7	-0.8
Severe depression (siblings)	3.6	4.0	4.5	2.0	2.1	-1.9
Ever smoked	3.5	6.1	18.1	4.3	-0.4	0.2
Had other major operations	3.3	4.0	9.5	3.1	1.5	-0.6
Past tobacco smoking	3.2	5.8	15.8	-4.0	-0.6	-1.1
Lupus	3.0	4.6	7.6	0.2	2.5	-2.8
High blood pressure (mother)	3.0	4.3	6.7	-0.8	-2.6	2.3
Breast cancer (self-reported)	3.0	3.5	4.4	1.6	1.9	-2.1
Bilateral oophorectomy (both ovaries removed)	2.9	3.4	8.5	2.9	0.9	0.9
Pack years adult smoking proportion	2.4	3.7	7.8	-1.8	-2.8	-0.3
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	8.8	1.4	3.0	-0.6
Medication: Ventolin 100micrograms inhaler	2.4	3.1	6.2	2.5	1.5	-0.8
Qualifications: NVQ or HND or HNC or equivalent	2.4	2.9	6.7	-2.6	-1.4	-0.0
Number of operations (self-reported)	2.4	3.5	6.3	2.5	1.8	1.1
Illnesses of siblings	2.3	3.2	4.9	-2.2	0.7	-2.0
Pulse wave reflection index	2.3	2.9	7.1	-0.6	1.1	-2.7
Comparative body size at age 10	2.3	6.4	11.2	-2.5	-3.3	1.4
Tinnitus: Yes, but not now, but have in the past	2.2	2.3	3.0	1.3	1.7	-1.5
Nervous feelings	2.2	4.1	9.6	0.7	3.1	-1.5
Ever taken oral contraceptive pill	2.2	2.4	4.7	1.4	-0.7	2.2
Pack years of smoking	2.2	3.2	6.7	-1.7	-2.6	-0.1
Financial difficulties in last 2 years	2.1	2.8	5.6	1.1	2.4	-1.2
Tense / ‘highly strung’	2.1	3.4	7.3	1.2	2.7	-1.2
Number of full brothers	2.1	2.6	7.3	2.7	0.6	0.5
Chest pain or discomfort	2.1	3.0	5.2	2.3	1.9	0.3
Had major operations	2.1	2.5	4.5	2.1	1.7	-0.5
Worry (Nagel 2018)	2.0	4.3	10.1	0.3	3.2	-1.7
Ever used hormone-replacement therapy (HRT)	2.0	2.5	6.8	2.6	-0.3	0.8
Medication: Metformin	2.0	2.8	7.0	2.6	0.6	1.0
Illness, injury, bereavement, stress in last 2 years	2.0	2.5	3.6	-1.9	-0.7	-1.8
Alzheimer’s Disease (in mother)	1.9	2.2	4.3	2.1	0.5	-1.4
Type 2 Diabetes (T2D) (2018)	1.9	3.6	7.0	2.6	-0.9	1.8
Ever highly irritable/argumentative for 2 days	1.9	2.3	4.7	2.2	0.4	-1.5
Smoking status: Previous	1.9	2.9	7.3	2.7	0.8	0.8
Mood swings	1.9	3.4	9.4	0.3	3.1	-0.8
Taking other prescription medications	1.8	2.7	4.4	2.1	-0.5	1.9
Number of incorrect matches in round	1.8	3.0	8.2	-2.9	-0.4	0.7
Exposure to tobacco smoke at home	1.8	2.1	3.3	1.8	1.7	0.2
Loud music exposure frequency	1.8	2.0	5.6	0.1	2.4	-0.6
Medication: Aspirin	1.8	2.4	4.2	1.1	-1.3	2.0
Medication: Bendroflumethiazide	1.8	2.7	6.9	-1.0	0.4	2.6
Unable to work because of sickness or disability	1.8	2.3	4.4	0.4	-1.5	2.1
Neuroticism (Nagel 2018)	1.7	4.1	11.7	0.2	3.4	-0.7
Verbal and Numeric Reasoning (VNR)	1.7	4.1	5.9	2.1	1.4	-2.4
Ever had hysterectomy (womb removed)	1.7	1.9	3.1	1.6	-0.0	1.8
Diverticular disease/diverticulitis (self-reported)	1.7	2.1	2.8	1.7	1.4	1.2
Worrier / anxious feelings	1.7	3.2	4.4	-1.5	1.7	-2.1
Asthma	1.7	3.3	5.3	2.1	2.3	0.3
Lung cancer (father)	1.7	2.0	5.8	2.4	0.2	0.2
Headache pain in last month	1.7	3.0	7.7	0.6	2.8	-0.9
Diabetes diagnosed by doctor	1.7	2.8	7.0	2.7	-0.1	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	3.7	1.9	1.4	0.5
Medication: Aspirin	1.7	2.2	4.1	1.0	-1.2	2.0
Systolic Blood Pressure	1.6	8.1	15.8	-1.8	-2.3	4.0
Current tobacco smoking	1.6	2.6	7.7	0.4	-2.8	0.0
Diabetes (self-reported)	1.6	2.5	5.2	2.3	-0.1	1.5
Falls in the last year	1.6	2.2	5.9	2.4	-0.6	-0.6
Hair/balding pattern: Pattern 3	1.6	2.4	3.8	1.1	1.5	-1.9
Breastfed as a baby	1.6	2.0	5.2	-0.8	-2.3	-0.3
Suffer from ‘nerves’	1.6	2.6	5.0	0.4	1.6	-2.2
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.9	2.0	0.4	1.1
Rheumatoid Arthritis	1.5	2.1	3.4	-1.7	0.2	1.8
Medication: Simvastatin	1.5	2.1	5.3	-0.6	-2.3	0.8
Medication: Blood pressure	1.5	2.7	5.7	-0.0	-1.5	2.4
Family relationship satisfaction	1.5	1.8	2.9	1.4	1.7	-0.7
Commuting to job workplace: Walk	1.5	1.6	2.3	-1.5	-0.8	1.3
Number of self-reported non-cancer illnesses	1.5	2.6	6.1	1.1	-0.7	2.5
Guilty feelings	1.5	2.3	5.1	2.3	1.3	0.3
Vascular/heart problems diagnosed by doctor	1.5	4.2	11.6	0.2	0.9	-3.4
Schizophrenia vs Biploar Disorder	1.4	1.8	4.2	2.0	1.0	0.5
Bipolar Disorder (2011)	1.4	1.4	3.2	-0.5	-1.8	-0.8
Mean Putamen Volume	1.4	1.6	4.0	0.6	0.6	-2.0
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	5.3	0.6	0.9	-2.3
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	6.8	1.1	2.6	0.7
Number of full sisters	1.4	1.7	4.9	2.2	-0.1	0.4
Hypertension (Self-reported)	1.4	3.9	10.1	-0.2	-1.3	3.2
Illnesses of siblings: Diabetes	1.4	1.7	3.0	1.7	-0.4	1.4
Medication: Blood pressure	1.4	2.7	7.1	0.2	-0.9	2.7
Myopia	1.4	2.0	5.5	-0.7	0.1	-2.3
Alzheimer’s Disease (including proxy)	1.3	1.8	2.7	1.6	1.0	-1.3
Prostate Cancer	1.3	1.8	3.3	-0.6	-1.8	1.4
High blood pressure	1.3	3.7	10.0	0.1	-1.0	3.2
Stomach or abdominal pain in last month	1.3	1.6	2.6	1.1	1.6	1.0
Father’s age at death	1.3	1.8	2.5	0.8	1.6	1.5
Gout (self-reported)	1.3	1.8	5.1	2.3	-0.0	0.5
Angina (self-reported)	1.3	1.6	3.2	1.0	0.9	1.8
Medication: Allopurinol	1.3	1.7	4.0	2.0	1.0	-0.1
Smoking status: Current	1.3	2.1	5.9	0.6	-2.4	0.2
Wears glasses or contact lenses	1.3	1.5	2.0	1.4	1.2	1.1
Supplements: Calcium	1.3	1.4	2.7	1.6	0.8	-0.9
Major Depression (MDD)	1.2	1.5	1.9	1.0	1.2	1.4
Coronary Artery Disease (CAD)	1.2	1.5	2.3	-0.2	-1.5	-1.4
Fasting Glucose	1.2	1.4	3.2	0.9	1.8	-0.4
Smoking Status	1.2	2.8	7.4	2.7	-1.0	0.1
Hair/balding pattern: Pattern 2	1.2	1.5	4.4	-0.0	-0.3	2.1
Mouth/teeth dental problems	1.2	1.8	4.6	2.1	0.5	0.8
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	4.5	2.1	0.2	-0.6
Fluid intelligence score	1.2	2.6	3.2	1.6	1.8	-1.4
Prospective memory result	1.2	1.5	3.6	-1.9	-0.3	0.9
Illnesses of mother	1.2	1.5	2.1	-1.4	1.5	-0.6
Birth weight	1.2	2.7	4.3	-2.1	0.8	-1.7
Commuting to job workplace: Car/motor vehicle	1.2	1.4	3.3	1.8	0.4	-0.9
Knee pain experienced in last month	1.2	1.8	2.5	0.9	1.5	1.6
Asthma (self-reported)	1.2	2.3	3.7	1.9	1.8	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.4	4.6	1.0	1.4	-2.1
Neuroticism	1.1	2.6	7.2	0.8	2.7	0.3
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	3.5	0.9	0.3	1.9
Systolic blood pressure, automated reading	1.1	3.2	7.5	-1.4	-0.5	2.7
Vitamin and mineral supplements	1.1	1.5	2.8	-0.5	-1.7	1.2
Alcohol usually taken with meals	1.1	1.8	2.9	0.6	-1.7	1.4
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	3.5	0.4	-0.1	1.9
Birth weight of first child	1.1	2.0	5.7	0.4	-0.2	-2.4
Medication: Omeprazole	1.1	1.3	2.5	-1.6	-0.8	0.9
Long-standing illness, disability or infirmity	1.1	1.7	3.5	1.2	-0.2	1.9
Medication: Gliclazide	1.1	1.3	3.5	1.9	0.3	-0.5
Alcohol drinker status: Never	1.1	1.4	3.9	-2.0	0.4	0.0
Crohns Disease (2012)	1.0	1.6	2.7	-1.6	1.3	-0.7
Type 2 Diabetes (T2D) (2012)	1.0	1.1	2.7	0.7	1.6	0.4
Ulcerative Colitis	1.0	1.4	2.7	-1.1	0.4	-1.7
Angina	1.0	1.4	2.2	1.0	0.9	1.5
Medication: Atenolol	1.0	1.3	2.5	-0.3	-1.1	1.6
Number of live births	1.0	1.5	3.9	0.5	-2.0	-0.6
Happiness	1.0	1.2	1.5	1.2	1.1	0.9
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.9	0.8	0.7	-1.7
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.5	-0.7	-0.6	-1.6
Pulse wave peak to peak time	1.0	1.2	2.2	-1.1	-0.5	1.5
Supplements: Vitamin C	1.0	1.2	1.8	1.3	0.7	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	3.0	-1.7	-0.2	0.7
Handedness (chirality/laterality): Left-handed	1.0	1.2	3.1	1.8	0.6	0.0
Qualifications: nursing, teaching	1.0	1.6	4.5	-2.1	-0.2	0.5
Hearing aid user	1.0	1.2	3.3	0.3	1.8	-0.3
Mother’s age at death	1.0	1.2	3.4	-1.8	-0.5	0.3
Commuting to job workplace: Public transport	1.0	1.2	2.9	-0.7	-0.4	1.7
Medication: Lisinopril	1.0	1.2	2.7	-0.3	-1.0	1.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	1.8	-1.2	-0.6	1.3
Basal cell carcinoma (self-reported)	1.0	1.1	2.6	-0.2	-0.9	-1.6
Depressed Affect (Nagel 2018)	0.9	1.9	5.5	0.5	2.3	-0.2
Cardiovascular Disease	0.9	3.0	7.6	-0.4	-1.1	2.8
Hypothyroidism (self reported)	0.9	2.0	3.1	1.4	1.8	1.0
Lung FVC	0.9	4.8	7.2	2.7	2.6	-0.7
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.4	0.4	1.8	-0.2
Fed-up feelings	0.9	1.7	2.7	-0.4	1.6	-1.5
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	1.8	0.6	1.4	1.0
Pain all over the body in last month	0.9	1.0	1.9	0.8	-1.4	0.6
Alcohol intake frequency.	0.9	2.0	3.7	-1.9	-0.8	1.3
Mineral and other dietary supplements	0.9	1.2	2.2	-1.5	-1.1	0.3
Osteoporosis (self-reported)	0.9	1.1	2.8	-0.6	-1.7	0.1
Irritability	0.9	1.5	2.4	0.4	1.4	-1.6
Heart attack/myocardial infarction (self-reported)	0.9	1.2	1.6	-1.0	-1.0	1.3
Depression (Nagel 2018)	0.8	1.2	3.0	0.1	0.6	1.7
Breast Cancer	0.8	1.8	4.5	-2.1	-0.2	-1.0
HbA1C	0.8	0.9	1.3	0.9	-0.9	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	2.4	-0.3	0.8	1.5
Medication: Levothyroxine sodium	0.8	1.4	3.4	0.8	1.8	0.5
Allergy	0.8	1.9	4.3	-2.1	-1.0	0.7
Neuroticism score	0.8	1.7	4.2	0.1	2.0	-1.0
Blood clot in the leg (DVT)	0.8	1.1	2.5	1.6	-0.8	0.2
Medication: Amlodipine	0.8	1.1	2.7	-1.6	0.4	0.6
Average weekly red wine intake	0.8	1.1	1.8	1.3	-0.4	1.2
Average weekly champagne plus white wine intake	0.8	1.1	2.4	0.0	-0.9	1.6
Supplements: Fish oil (including cod liver oil)	0.8	1.1	1.8	1.0	1.4	-0.6
High cholesterol (Self-reported)	0.8	1.4	2.2	-1.5	-1.2	0.7
Age started oral contraceptive pill	0.8	1.0	1.5	-0.9	0.8	-1.2
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.7	1.6	-0.6	0.2
Irritable Bowel Disease (IBD)	0.7	1.7	3.8	-2.0	1.0	-0.4
Reaction Time	0.7	1.3	2.8	1.1	0.1	1.7
Blood Red Count	0.7	6.9	11.2	-3.3	-2.1	2.2
Number of treatments/medications taken	0.7	1.3	3.9	0.1	0.2	2.0
Sensitivity / hurt feelings	0.7	1.2	2.7	-1.0	1.6	-0.2
Diabetes (mother)	0.7	0.9	2.6	1.6	-0.1	-0.4
Age when periods started (menarche)	0.7	1.7	3.1	-1.4	0.3	-1.7
Hearing difficulty/problems with background noise	0.7	1.1	1.6	1.3	1.2	-0.6
Qualifications: None of the above	0.7	1.5	3.2	-0.1	-1.1	1.8
Medication: Lansoprazole	0.7	0.8	2.0	0.1	-1.4	0.6
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.7	0.6	0.5	-1.7
Number of children fathered	0.7	0.8	2.2	1.5	-0.3	-0.1
Age at first live birth	0.7	1.2	2.6	-1.0	0.2	-1.6
Age at last live birth	0.7	1.0	2.6	-0.4	0.3	-1.6
Illnesses of father: Heart disease	0.7	1.0	2.6	0.5	1.6	0.1
Eye problems/disorders: Cataract	0.7	0.8	1.3	-1.1	0.6	0.7
Medication: Atorvastatin	0.7	0.8	1.8	0.3	1.3	0.8
Crohns Disease (2017)	0.6	1.4	3.1	-1.8	1.0	-0.2
Average weekly spirits intake	0.6	0.7	1.9	-0.3	-0.3	-1.4
Medication for hormone replacement therapy	0.6	0.7	1.8	0.3	1.4	-0.4
Leg fat-free mass (left)	0.6	3.0	6.6	-2.6	-1.5	0.3
Relative age voice broke	0.6	0.9	1.7	1.3	-0.4	-0.9
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.3	1.3	1.5	-0.3
Leg predicted mass (left)	0.6	3.0	6.6	-2.6	-1.5	0.4
Heart attack	0.6	0.8	1.3	-0.7	-0.6	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.3	-1.5	-0.1	0.2
Pulse wave Arterial Stiffness index	0.6	0.7	1.4	0.8	0.3	-1.2
Length of working week for main job	0.6	0.6	1.3	0.1	-1.1	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.8	1.7	0.3	-0.1
Emphysema/chronic bronchitis	0.6	0.7	1.1	0.7	-0.6	-1.0
Friendships satisfaction	0.6	0.7	1.2	1.1	-0.3	0.9
Medication for cholesterol	0.6	1.0	2.7	-0.2	0.4	-1.6
Illnesses of father: None of the above (group 1)	0.6	0.8	1.5	-1.2	-0.9	0.3
Commuting to job workplace: Cycle	0.6	0.8	0.9	-1.0	-0.9	-0.7
Heart disease (siblings)	0.6	0.8	1.3	1.2	-0.5	0.8
Ovarian Cancer	0.5	0.7	1.4	0.8	-1.2	-0.3
Schizophrenia (2014)	0.5	1.0	1.9	0.8	-1.4	0.7
Blood White Count	0.5	3.8	11.2	-3.4	-0.5	0.1
Respiratory disease	0.5	1.1	2.4	1.6	0.6	0.7
Relative age of first facial hair	0.5	0.9	1.8	1.0	-0.2	-1.4
Hand grip strength (right)	0.5	1.2	3.1	-1.8	-0.4	-0.7
Average weekly fortified wine intake	0.5	0.5	0.8	0.5	-0.9	0.8
Qualifications: CSEs or equivalent	0.5	0.7	1.9	0.4	-1.4	0.0
Alcohol intake versus 10 years previously	0.5	0.7	2.1	0.3	-1.4	-0.0
Mouth/teeth dental problems: Dentures	0.5	0.9	2.5	-1.6	0.3	0.5
Exposure to tobacco smoke outside home	0.5	0.6	1.3	0.7	-1.1	0.1
Worry too long after embarrassment	0.5	0.9	1.1	-1.0	1.0	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.3	1.1	-0.3	0.7
Eye problems/disorders: None of the above	0.5	0.6	1.5	-0.4	-0.1	-1.2
Medication for pain relief, constipation, heartburn	0.5	0.9	2.2	0.4	0.4	-1.5
Medication: Ibuprofen	0.5	0.6	1.6	-1.2	-0.4	-0.2
Mean time to correctly identify matches	0.5	0.9	1.4	0.8	0.8	1.2
Ever had bowel cancer screening	0.5	0.6	1.7	0.2	0.2	1.3
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.6	-1.3	0.0	0.6
Average weekly beer plus cider intake	0.5	0.7	1.2	-0.4	-0.8	-1.1
Risk taking	0.5	0.8	2.3	1.5	0.3	-0.2
Ever had prostate specific antigen (PSA) test	0.5	0.6	0.9	-0.3	-0.9	1.0
Diastolic blood pressure, automated reading	0.5	1.7	4.8	0.0	0.5	2.2
Ever depressed for a whole week	0.5	0.6	1.5	0.5	1.2	-0.0
Intelligence (Savage-Jansen 2018)	0.4	1.1	1.6	1.1	0.8	-1.3
Age at First Birth	0.4	0.5	0.6	0.7	0.8	-0.7
Primary Biliary Cirrhosis	0.4	0.6	1.2	-1.1	0.0	0.8
BMI	0.4	2.2	2.9	-1.7	-1.0	1.6
Lung FEV1/FVC ratio	0.4	2.3	5.1	0.6	-2.3	-1.2
Hearing difficulty/problems: Yes	0.4	0.6	1.5	1.2	-0.1	-0.5
Multivitamins +/- minerals	0.4	0.5	1.0	-0.3	1.0	-0.6
Supplements: Glucosamine	0.4	0.5	0.9	-0.9	0.9	0.0
Impedance of leg (left)	0.4	1.8	4.4	2.1	1.0	0.2
Medication: Ramipril	0.4	0.6	1.3	-1.1	-0.6	0.1
Peak expiratory flow (PEF)	0.4	0.9	2.2	1.5	-0.0	-0.7
Shortness of breath walking on level ground	0.4	0.4	0.9	0.6	0.9	0.3
Heart disease (mother)	0.4	0.5	1.0	0.3	0.5	1.0
Comparative height size at age 10	0.4	2.1	3.3	-1.8	-1.6	0.8
Leg fat-free mass (right)	0.4	2.2	5.2	-2.3	-1.2	0.2
Leg predicted mass (right)	0.4	2.3	5.3	-2.3	-1.2	0.2
Miserableness	0.4	0.7	0.9	0.8	1.0	0.7
Basal metabolic rate	0.4	2.0	3.3	-1.8	-1.5	0.6
Fractured/broken bones in last 5 years	0.4	0.5	0.9	0.9	-0.2	-0.7
Cholesterol lowering medication	0.4	0.7	0.9	0.7	-0.9	0.8
Bipolar Disorder (2018)	0.3	0.6	0.6	-0.8	-0.8	-0.7
Ulcerative Colitis (UC)	0.3	0.6	1.4	-1.2	0.3	-0.5
LDL Cholesterol	0.3	0.5	0.6	-0.8	-0.7	-0.7
Blood Platelet Count	0.3	2.9	7.7	-0.5	0.9	-2.8
Chronotype (morning person)	0.3	0.6	1.7	-1.3	-0.3	-0.2
Hand grip strength (left)	0.3	0.7	1.1	-1.0	0.2	-1.1
Supplements: Zinc	0.3	0.4	0.7	0.8	-0.5	0.4
Waist circumference	0.3	1.2	1.5	-1.2	-0.9	1.1
Weight	0.3	1.4	2.1	-1.5	-1.0	1.0
Medication: Cholesterol lowering	0.3	0.4	0.7	-0.5	-0.8	0.6
Depression (self-reported)	0.3	0.4	0.7	-0.6	-0.2	0.8
Arm fat mass (right)	0.3	1.1	2.0	-1.4	-1.0	0.5
Hair/balding pattern: Pattern 4	0.3	0.7	1.2	-0.2	-1.1	0.8
Health satisfaction	0.3	0.4	0.7	0.9	0.3	0.6
Qualifications: College or University degree	0.3	0.8	1.9	1.4	0.7	0.3
Migraine (self-reported)	0.3	0.4	0.8	0.5	0.3	0.9
Overall health rating	0.3	0.6	1.0	-0.8	-0.6	1.0
Leg pain on walking	0.3	0.4	0.8	0.9	0.4	0.5
Whole body fat-free mass	0.3	1.6	2.4	-1.6	-1.4	0.6
Loneliness, isolation	0.3	0.5	1.0	1.0	0.5	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.7	-0.4	-0.8	-0.8
Whole body water mass	0.3	1.8	2.7	-1.6	-1.5	0.6
Eye problems/disorders: Glaucoma	0.3	0.3	0.6	0.8	0.5	0.2
Arm fat-free mass (left)	0.3	1.4	1.8	-1.3	-1.3	0.7
Pain experienced in last month	0.3	0.6	0.8	-0.4	-0.9	-0.9
Impedance of whole body	0.3	1.3	2.5	1.0	1.6	-0.6
Arm predicted mass (left)	0.3	1.4	2.0	-1.3	-1.4	0.7
Schizophrenia (2018)	0.2	0.3	0.7	0.8	-0.5	-0.1
Alzheimer’s Disease (in father)	0.2	0.2	0.4	-0.6	0.2	-0.3
HDL Cholesterol	0.2	0.3	0.8	-0.9	-0.5	-0.1
Neuroticism (2016)	0.2	0.3	0.5	0.7	0.5	-0.5
Height	0.2	3.5	5.4	-2.3	-2.3	-0.0
Waist Hip Ratio (WHR)	0.2	0.8	1.8	-0.7	-0.0	1.4
Allergy or Eczema	0.2	0.6	1.5	0.6	1.2	-0.0
Tanning	0.2	1.8	5.5	-2.4	-0.1	0.1
Impedance of leg (right)	0.2	0.9	2.4	1.5	0.5	0.3
Trunk fat percentage	0.2	0.7	1.8	-1.4	-0.0	0.5
Sitting height	0.2	1.2	1.4	1.2	-0.9	1.2
Body mass index (BMI)	0.2	0.7	1.3	-1.1	-0.7	0.4
Trunk fat mass	0.2	0.8	1.8	-1.3	-0.5	0.7
Had menopause	0.2	0.2	0.5	0.1	-0.7	-0.5
Arm fat percentage (right)	0.2	0.7	1.9	-1.4	-0.4	0.2
Trunk fat-free mass	0.2	1.0	2.0	-0.8	-1.4	0.6
Hip circumference	0.2	0.8	1.2	-0.9	-1.1	0.7
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	0.1	1.2	-0.2
Impedance of arm (left)	0.2	0.8	1.8	0.6	1.4	-0.4
Trunk predicted mass	0.2	1.1	2.1	-0.8	-1.4	0.8
Glaucoma (self-reported)	0.2	0.3	0.4	0.5	-0.4	0.7
Forced vital capacity (FVC), Best measure	0.2	0.8	0.8	0.9	0.9	-0.8
Arm fat-free mass (right)	0.2	1.0	1.6	-1.0	-1.3	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.5	-0.1	-0.5	-0.7
Whole body fat mass	0.2	0.9	1.9	-1.4	-0.6	0.7
Leg fat mass (right)	0.2	1.0	1.8	-1.3	-0.7	0.8
Arm predicted mass (right)	0.2	1.2	2.3	-0.8	-1.5	0.8
Osteoarthritis (self-reported)	0.2	0.3	0.6	-0.5	-0.8	-0.3
Arm fat mass (left)	0.2	1.0	1.6	-1.2	-1.0	0.6
Leg fat mass (left)	0.2	0.9	1.6	-1.3	-0.7	0.7
Bipolar Disorder or Schizophrenia	0.1	0.4	0.8	0.1	-0.9	-0.5
Body Mass Index (BMI) (2010)	0.1	0.1	0.3	0.2	-0.2	0.6
Hair Pigment	0.1	2.6	3.5	1.5	1.4	-1.9
Medication: Co-codamol	0.1	0.1	0.2	-0.0	-0.0	0.5
Maternal smoking around birth	0.1	0.2	0.3	0.2	0.4	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.6	-0.4	-0.8	-0.3
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.0	0.4	-0.2
Forced vital capacity (FVC)	0.1	0.4	0.8	0.9	0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.3	-0.5	-0.6	0.0
Impedance of arm (right)	0.1	0.6	1.8	0.3	1.3	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.4	0.2	0.7	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.9	0.4	-0.0	-0.9
Noisy workplace	0.1	0.1	0.1	0.2	-0.3	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.5	1.4	0.2	0.1	-1.2
Standing height	0.1	0.7	1.2	-0.8	-0.4	1.1
Medication: Paracetamol	0.1	0.2	0.6	0.2	0.8	-0.2
High blood pressure (siblings)	0.1	0.1	0.2	0.3	0.3	0.4
Body fat percentage	0.1	0.5	1.3	-1.1	-0.1	0.5
Leg fat percentage (right)	0.1	0.5	0.8	-0.7	-0.3	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.2	-0.5	0.1
Wheeze or whistling in the chest in last year	0.1	0.2	0.4	0.6	0.0	-0.4
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	-0.1	-0.3	-0.4
Arm fat percentage (left)	0.1	0.5	1.3	-1.1	-0.5	0.2
Back pain experienced in last month	0.1	0.2	0.4	-0.6	-0.4	0.2
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	0.1	0.2	-0.6
Medication: Paracetamol	0.1	0.2	0.4	0.6	0.3	0.0
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.1	0.2	-0.5
Leg fat percentage (left)	0.1	0.4	0.8	-0.5	-0.1	0.9
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.2	-0.4	-0.0
Triglycerides	0.0	0.1	0.1	-0.2	-0.3	-0.0
Blood Eosinophil Count	0.0	0.2	0.4	0.4	-0.2	0.6
Heel T-Score	0.0	0.2	0.3	-0.2	-0.6	-0.5
Townsend deprivation index at recruitment	0.0	0.0	0.1	-0.1	0.1	0.3
Neck or shoulder pain in last month	0.0	0.0	0.1	0.1	0.2	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.0	0.1	0.2	0.3	0.1

Hub : Genes

VSNL1

Models

Trait associations