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chr2:187,360,440-189,122,229

Best TWAS P=2.21e-24 · Best GWAS P=2.49e-24 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Tibial	CALCRL	0.27	0.33	lasso	3	0.32	1.1e-25	10.2	10.2	2.2e-24	0.99	0.00	1.00	TRUE
5	GTEx	Nerve Tibial	CALCRL	0.09	0.04	enet	9	0.08	5.2e-06	10.2	9.8	8.4e-23	0.90	0.00	1.00	FALSE
1	GTEx	Artery Aorta	CALCRL	0.16	0.17	lasso	2	0.15	8.4e-09	10.2	9.8	1.7e-22	0.95	0.00	1.00	FALSE
4	GTEx	Cells Transformed fibroblasts	TFPI	0.07	0.04	lasso	4	0.03	1.6e-03	7.6	7.7	1.4e-14	0.65	0.36	0.42	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	CALCRL	0.03	0.04	blup	62	0.04	1.4e-05	8.0	-7.5	9.1e-14	-0.76	0.87	0.11	FALSE
8	NTR	Blood	CALCRL	0.02	0.03	lasso	7	0.02	3.6e-08	7.2	-6.9	6.0e-12	-0.74	1.00	0.00	FALSE
3	GTEx	Brain Frontal Cortex BA9	AC007319.1	0.16	0.08	lasso	7	0.10	9.9e-04	7.3	6.6	3.9e-11	0.73	0.25	0.29	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	AC007319.1	0.17	0.10	lasso	3	0.13	1.9e-07	6.1	6.5	1.0e-10	0.65	0.81	0.16	FALSE
9	The Cancer Genome Atlas	Colon Adenocarcinoma	TFPI	0.08	0.04	blup	51	0.03	6.0e-03	6.1	5.3	1.3e-07	0.60	0.03	0.35	FALSE
7	GTEx	Testis	AC007319.1	0.33	0.22	lasso	6	0.30	1.2e-13	6.1	5.1	2.8e-07	0.53	0.82	0.17	FALSE