TWAS hub - STMN3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0730	0.0240	9.8e-05	0.019	0.034	0.044	0.039	0.046	1.9e-03	4.5e-05	4.2e-06	1.2e-05	2.8e-06
2	GTEx	Brain Cerebellar Hemisphere	0.3930	0.1030	5.9e-05	0.076	NA	0.138	NA	0.222	5.3e-03	NA	2.2e-04	NA	2.1e-06
3	GTEx	Brain Cerebellum	0.3310	0.0870	1.4e-05	0.119	NA	0.179	NA	0.197	2.2e-04	NA	5.7e-06	NA	1.8e-06
4	GTEx	Brain Cortex	0.2540	0.0840	1.3e-03	0.093	NA	0.025	NA	0.108	1.6e-03	NA	6.9e-02	NA	6.8e-04
5	GTEx	Cells Transformed fibroblasts	0.2080	0.0570	1.4e-04	0.093	NA	0.130	NA	0.109	1.9e-07	NA	5.9e-10	NA	1.5e-08
6	GTEx	Pituitary	0.4350	0.1060	3.1e-04	0.005	NA	0.064	NA	0.053	2.4e-01	NA	1.1e-02	NA	1.9e-02
7	GTEx	Whole Blood	0.0970	0.0370	2.0e-03	-0.001	NA	-0.003	NA	0.004	4.4e-01	NA	7.0e-01	NA	1.2e-01
8	METSIM	Adipose	0.1966	0.0432	5.5e-12	0.082	0.088	0.114	0.102	0.099	3.0e-12	4.4e-13	1.0e-16	5.7e-15	1.3e-14
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0226	0.0124	2.6e-03	0.019	0.021	0.015	NA	0.013	2.6e-03	1.7e-03	7.5e-03	NA	1.3e-02
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.0720	0.0400	7.1e-04	0.009	0.046	0.035	NA	0.031	7.3e-02	4.2e-04	2.0e-03	NA	3.2e-03
11	TCGA	Skin Cutaneous Melanoma	0.2440	0.1060	3.1e-03	0.028	0.044	0.097	NA	0.040	6.1e-02	2.5e-02	1.5e-03	NA	3.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Irritable Bowel Disease (IBD)	22.2	52.9	100.0	-7.5	-10.0	-8.8	-8.7	-1.0	-7.2	8.3	7.5	-7.0	-5.5	3.8
Crohns Disease (2012)	16.6	26.8	37.4	-5.7	-5.8	-5.9	-6.1	-1.4	-5.4	5.8	4.1	-5.9	-5.5	3.0
Crohns Disease (2017)	16.5	36.1	62.3	-6.3	-7.9	-7.2	-6.8	-1.4	-6.3	6.5	6.7	-5.7	-4.9	3.4
Ulcerative Colitis	13.3	19.2	29.7	-5.3	-5.4	-5.2	-5.2	-0.6	-4.2	4.7	4.1	-4.6	-3.5	3.1
Allergy	13.2	30.4	45.4	5.9	5.0	6.1	6.6	2.4	4.9	-6.7	-4.6	6.4	6.5	-3.7
Ulcerative Colitis (UC)	12.9	24.2	50.4	-4.9	-7.1	-6.0	-6.3	0.8	-4.8	5.6	5.1	-4.5	-3.1	2.3
Prostate Cancer	12.6	17.7	31.6	-5.5	-3.2	-5.3	-4.4	1.7	-2.9	3.7	5.6	-4.0	-4.2	4.2
Allergy or Eczema	12.1	32.0	53.5	-5.7	-5.6	-7.1	-7.3	-2.0	-4.5	6.8	4.7	-6.4	-6.4	3.1
Wheeze or whistling in the chest in last year	12.1	21.6	32.1	-5.4	-3.7	-5.1	-5.7	-4.6	-4.7	4.4	2.6	-5.5	-5.3	3.0
Hayfever, allergic rhinitis or eczema	11.4	24.7	38.0	-4.9	-5.2	-6.1	-6.2	-1.3	-4.4	6.0	4.6	-5.4	-5.4	3.0
Lung FVC	11.1	56.4	89.7	9.1	8.9	9.1	7.5	4.6	6.4	-9.5	-6.7	7.6	7.1	-4.0
Respiratory disease	8.9	19.8	32.8	-5.7	-3.5	-4.6	-4.9	-3.8	-3.3	4.3	2.5	-5.5	-5.7	3.9
Asthma	8.5	16.7	32.3	-4.9	-3.0	-4.4	-4.4	-3.0	-3.2	3.6	2.9	-5.2	-5.7	3.4
Current tobacco smoking	8.4	13.7	26.8	-4.5	-5.2	-4.4	-4.4	-0.5	-2.6	4.1	3.6	-3.7	-3.0	2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	8.3	17.5	25.9	4.8	5.1	4.6	3.8	4.1	3.7	-4.8	-4.2	4.2	4.1	-2.0
Asthma (self-reported)	8.0	15.9	29.9	-4.8	-3.0	-4.3	-4.3	-2.8	-3.1	3.5	2.9	-5.0	-5.5	3.4
Number of self-reported non-cancer illnesses	7.7	13.4	26.2	-4.3	-5.1	-4.2	-4.3	-1.0	-2.5	3.9	3.4	-3.7	-3.4	2.7
Smoking status: Current	7.0	11.2	21.3	-4.0	-4.6	-4.0	-4.0	-0.1	-2.2	3.7	3.2	-3.5	-2.9	1.9
Forced vital capacity (FVC)	6.7	25.9	38.3	5.0	5.9	6.0	5.7	4.1	5.0	-6.2	-4.3	5.5	5.2	-1.2
Smoking Status	6.6	15.8	26.5	-5.1	-3.8	-4.6	-4.1	-2.5	-3.7	3.8	3.2	-4.3	-3.9	4.1
Diastolic blood pressure, automated reading	5.8	18.0	38.2	-3.7	-5.3	-5.5	-6.2	1.3	-3.6	4.8	4.2	-4.4	-3.4	1.3
Type 2 Diabetes (T2D) (2018)	5.0	9.3	18.0	-3.3	-4.2	-3.3	-2.8	-2.0	-3.2	3.2	3.2	-3.0	-2.8	1.9
Forced vital capacity (FVC), Best measure	5.0	18.3	29.8	4.0	5.3	5.0	4.6	3.5	4.0	-5.5	-3.9	4.4	4.1	-0.6
Forced expiratory volume in 1-second (FEV1)	4.9	16.5	21.6	4.2	4.5	4.5	4.1	4.0	4.5	-4.6	-3.3	4.4	4.0	-1.2
Illnesses of siblings: Diabetes	4.9	6.0	9.8	-2.6	-2.4	-3.1	-2.3	-2.7	-1.7	2.1	1.0	-2.9	-3.1	2.1
Leg fat percentage (left)	4.7	16.8	26.7	-3.4	-3.9	-4.9	-5.2	-4.6	-4.8	3.7	1.8	-4.9	-4.7	-0.1
Medication: Omeprazole (e.g. Zanprol)	4.6	5.5	12.2	-2.1	-1.8	-3.0	-2.9	-2.2	-1.7	3.5	1.3	-2.6	-2.7	0.2
Systolic blood pressure, automated reading	4.4	12.7	21.6	-3.4	-3.9	-4.6	-4.4	-0.5	-3.1	2.9	2.7	-4.6	-4.6	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	4.4	5.9	10.8	-2.8	-3.3	-3.0	-2.5	0.6	-0.7	2.4	3.1	-2.8	-2.1	1.7
Medication: Blood pressure	4.4	8.3	14.3	-3.1	-3.3	-3.4	-3.7	-0.2	-1.5	2.7	2.2	-3.8	-3.6	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.3	5.1	9.5	-1.5	-2.8	-2.7	-2.7	-1.8	-3.1	1.8	0.7	-3.0	-2.4	0.6
Pack years adult smoking proportion	4.2	6.4	14.8	-1.3	-3.9	-3.2	-2.8	-1.1	-2.8	3.2	2.8	-2.2	-1.8	-0.5
Long-standing illness, disability or infirmity	4.2	6.5	12.4	-2.4	-3.1	-2.3	-2.6	-3.3	-3.5	1.7	1.6	-2.7	-2.6	0.6
Blood Platelet Count	4.1	47.1	72.1	-7.2	-7.2	-8.5	-7.0	-2.5	-6.4	7.7	6.4	-8.0	-8.3	3.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.1	13.0	19.2	3.6	4.2	3.9	3.7	3.5	3.7	-4.4	-3.2	3.7	3.5	-0.7
Qualifications: CSEs or equivalent	4.0	5.3	10.1	-2.6	-2.2	-2.5	-1.8	-1.6	-1.3	3.2	1.7	-2.9	-2.7	2.0
Leg fat percentage (right)	4.0	14.4	22.8	-3.2	-3.7	-4.4	-4.7	-4.5	-4.8	3.1	1.7	-4.4	-4.2	-0.1
Qualifications: NVQ or HND or HNC or equivalent	4.0	4.9	8.2	-2.8	-2.0	-2.9	-2.5	-1.1	-0.9	2.6	2.1	-2.0	-1.8	2.6
Illness, injury, bereavement, stress in last 2 years	4.0	4.9	8.6	2.9	2.0	2.2	1.9	2.1	1.3	-2.3	-2.8	1.9	2.2	-2.4
Qualifications: College or University degree	3.9	12.4	20.3	3.5	4.5	4.5	4.1	1.3	2.6	-3.8	-3.2	4.2	3.7	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	3.8	5.8	14.9	-1.9	-3.9	-2.9	-2.9	0.5	-1.2	2.0	3.1	-2.5	-2.3	1.0
Hair/balding pattern: Pattern 2	3.7	4.7	7.6	-2.2	-2.8	-2.5	-2.2	-0.4	-1.9	2.7	2.5	-1.9	-2.1	1.5
Diverticular disease/diverticulitis (self-reported)	3.6	4.3	9.3	1.9	2.1	3.0	1.9	1.5	2.3	-0.9	-0.9	2.9	2.7	-1.5
Medication: Ventolin 100micrograms inhaler	3.6	4.6	10.4	-3.2	-2.6	-2.2	-2.2	0.1	-1.6	1.9	1.9	-1.7	-2.0	2.6
Pack years of smoking	3.6	5.3	12.4	-1.1	-3.5	-2.9	-2.7	-1.0	-2.7	2.8	2.5	-1.9	-1.4	-0.6
Diabetes (self-reported)	3.5	5.4	15.4	-2.3	-3.9	-2.5	-1.9	-1.4	-2.8	2.0	2.5	-2.0	-1.8	1.4
Body fat percentage	3.4	13.3	20.3	-2.9	-3.6	-4.3	-4.4	-4.5	-4.3	3.5	1.7	-4.1	-3.9	-0.5
Number of incorrect matches in round	3.3	5.5	11.0	2.7	3.2	2.6	2.1	0.1	2.2	-2.4	-3.3	2.1	1.8	-1.7
Emphysema/chronic bronchitis	3.3	3.7	7.2	-2.7	-2.0	-2.0	-1.7	-2.1	-1.7	2.6	1.3	-1.4	-1.1	2.0
Diabetes diagnosed by doctor	3.3	5.4	10.6	-2.4	-3.3	-2.5	-1.6	-2.5	-2.6	1.9	2.0	-2.4	-2.3	1.3
Ovarian Cancer	3.1	4.1	7.4	-2.7	-2.7	-2.6	-2.0	0.7	-1.0	1.6	2.0	-1.9	-1.1	2.6
Blood White Count	3.1	22.8	46.3	-6.1	-5.2	-5.5	-4.1	-1.6	-3.5	6.8	4.1	-4.3	-4.2	5.0
Other serious medical condition/disability diagnosed by doctor	3.0	3.9	7.4	-1.8	-1.6	-1.8	-2.4	-2.0	-2.7	1.3	1.1	-2.6	-2.7	0.8
Pain all over the body in last month	3.0	3.2	5.8	-1.4	-2.0	-1.8	-2.4	-1.1	-1.9	2.3	0.5	-2.3	-2.0	-1.1
Mouth/teeth dental problems: Dentures	3.0	5.0	14.1	-1.9	-2.2	-2.3	-2.6	-2.2	-3.8	1.8	0.4	-2.7	-2.2	0.4
Leg fat mass (left)	3.0	11.5	20.2	-2.9	-3.2	-3.8	-4.5	-3.7	-4.0	3.0	1.6	-4.0	-4.0	-0.1
HDL Cholesterol	2.9	4.9	10.3	3.2	2.8	2.1	2.0	1.9	1.5	-2.4	-1.1	2.0	1.8	-2.7
Taking other prescription medications	2.9	4.4	8.4	-2.0	-2.3	-1.8	-2.5	-2.9	-1.7	1.7	0.3	-2.6	-2.8	0.9
Whole body fat mass	2.9	12.3	21.9	-3.2	-3.2	-4.1	-4.7	-3.7	-4.0	3.3	1.6	-4.1	-4.0	0.1
Chronic bronchitis/emphysema (father)	2.8	3.2	6.6	-2.4	-2.2	-1.6	-1.8	-2.6	-1.5	1.5	1.5	-1.6	-1.3	1.4
Medication: Ramipril	2.8	3.6	12.9	-2.0	-3.6	-2.0	-2.1	0.1	-0.3	1.8	1.5	-2.2	-1.7	1.1
Hip circumference	2.8	12.1	25.1	-2.7	-2.3	-3.7	-5.0	-3.7	-4.2	3.2	1.5	-4.3	-4.5	-0.1
Leg fat mass (right)	2.8	10.8	18.8	-2.8	-3.1	-3.6	-4.3	-3.7	-4.0	2.7	1.5	-3.9	-3.8	-0.0
Trunk fat percentage	2.7	11.0	19.3	-2.5	-3.0	-3.8	-3.9	-4.4	-3.9	3.5	1.4	-3.8	-3.5	-0.8
Waist circumference	2.7	10.0	16.4	-2.7	-2.6	-3.7	-4.0	-4.0	-3.8	2.3	1.1	-3.7	-3.9	0.1
Cardiovascular Disease	2.6	8.5	18.3	-2.3	-4.3	-4.0	-2.9	-0.2	-1.5	3.4	3.2	-3.5	-3.1	0.6
Medication: Metformin	2.5	3.5	10.8	-2.1	-3.3	-2.1	-0.8	-0.9	-1.4	1.8	2.0	-1.7	-1.4	1.9
Maternal smoking around birth	2.5	3.7	8.0	-1.6	-1.7	-2.3	-2.4	-1.3	-2.0	1.2	0.9	-2.8	-2.8	0.5
Medication for pain relief, constipation, heartburn	2.5	4.2	9.6	0.6	2.1	2.2	3.1	1.1	2.0	-2.3	-1.0	2.7	2.8	0.8
Medication for cholesterol	2.5	3.8	8.4	2.5	2.4	2.0	2.9	-0.5	0.7	-1.5	-1.3	2.2	2.2	-1.9
Financial difficulties in last 2 years	2.4	3.2	6.0	-2.4	-1.4	-2.0	-1.9	-1.7	-1.3	1.4	1.1	-1.9	-2.0	2.1
Illnesses of mother	2.4	3.0	5.4	2.0	2.1	2.3	1.9	0.6	1.5	-1.9	-1.2	1.8	1.6	-1.4
Age at first live birth	2.4	4.3	8.9	2.0	2.6	3.0	2.4	0.9	1.8	-2.3	-1.7	2.4	1.8	-0.9
Depression (Nagel 2018)	2.3	3.5	5.8	-2.4	-2.4	-2.2	-2.2	0.0	-0.4	2.0	1.5	-2.2	-1.9	1.7
Severe depression (siblings)	2.3	2.6	5.5	-1.9	-1.4	-2.2	-1.6	-1.1	-0.6	1.7	0.6	-2.1	-2.3	0.9
Trunk fat mass	2.3	10.1	16.8	-2.7	-2.7	-3.6	-4.1	-3.9	-3.6	3.2	1.2	-3.7	-3.6	-0.5
Arm fat percentage (right)	2.3	9.2	18.0	-1.7	-2.8	-3.4	-3.2	-4.2	-3.9	2.6	1.0	-3.6	-3.6	-1.2
Arm fat mass (right)	2.3	9.3	15.3	-2.0	-2.4	-3.3	-3.9	-3.9	-3.8	2.6	0.8	-3.7	-3.9	-0.9
Frequency of tiredness / lethargy in last 2 weeks	2.2	3.6	8.1	-2.0	-2.8	-1.9	-2.2	-1.7	-1.3	2.7	0.6	-2.0	-1.4	0.7
Mouth/teeth dental problems: Mouth ulcers	2.2	3.5	7.2	2.2	2.4	1.9	1.8	1.8	1.3	-2.7	-1.1	2.1	1.8	-1.0
BMI	2.1	12.0	21.4	-1.7	-2.4	-3.6	-4.6	-4.1	-4.6	2.8	0.9	-4.5	-4.6	-0.9
Depression (self-reported)	2.1	2.6	7.4	2.4	0.1	1.7	1.4	1.4	1.1	-1.4	-0.8	1.3	1.7	-2.7
Medication: Omeprazole	2.1	2.6	7.1	-1.3	-0.8	-1.8	-1.7	-2.2	-1.3	2.7	0.1	-1.8	-1.7	-0.3
Arm fat percentage (left)	2.1	8.5	17.4	-1.6	-2.7	-3.3	-3.2	-4.2	-3.7	2.4	1.0	-3.4	-3.4	-1.2
Eye problems/disorders: Cataract	2.1	2.4	5.8	0.1	0.5	1.8	1.8	1.6	2.2	-1.2	-0.3	1.9	2.4	0.9
Arm fat mass (left)	2.1	8.6	14.4	-2.0	-2.5	-3.2	-3.8	-3.7	-3.6	2.4	0.9	-3.5	-3.6	-0.8
Systolic Blood Pressure	2.0	9.9	17.5	-2.6	-4.2	-3.8	-3.6	1.3	-1.9	3.3	2.9	-4.1	-3.8	0.8
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.2	6.5	-2.0	-1.8	-1.8	-2.6	-0.9	-0.8	2.3	1.2	-2.4	-1.7	1.1
Vascular/heart problems diagnosed by doctor	2.0	5.4	10.7	2.1	3.2	3.0	2.6	-0.2	1.2	-1.4	-2.2	3.3	3.0	-1.0
High blood pressure	1.9	5.2	9.9	-2.2	-3.0	-2.8	-2.5	0.4	-1.2	1.6	2.3	-3.1	-3.0	1.1
Pain experienced in last month	1.9	3.2	7.1	1.4	1.3	1.7	2.7	2.2	2.1	-1.7	0.0	2.0	2.4	0.5
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	4.1	-1.4	-1.6	-2.0	-1.2	0.4	0.6	-0.0	1.4	-1.9	-1.7	2.0
Chronic bronchitis/emphysema (mother)	1.8	2.1	4.0	-1.2	-2.0	-1.2	-1.0	-1.9	-1.7	0.7	1.1	-1.7	-1.9	0.0
Medication: Aspirin	1.8	2.3	7.3	-0.8	-2.7	-1.8	-1.4	-0.5	-0.7	2.0	1.4	-1.8	-1.7	-0.3
Hypertension (Self-reported)	1.8	5.1	10.3	-2.2	-2.7	-2.7	-2.6	0.0	-1.4	1.6	2.1	-3.2	-3.0	1.3
Irritability	1.8	3.0	6.5	-2.5	-0.7	-1.5	-1.6	-1.4	-1.4	0.7	1.0	-2.2	-2.4	2.5
Commuting to job workplace: Cycle	1.8	2.2	4.3	1.7	1.6	1.8	2.1	0.2	1.6	-1.1	-1.1	1.6	1.6	-1.0
Rheumatoid Arthritis	1.7	2.4	5.7	-0.2	-1.2	-1.1	-2.1	-1.5	-2.4	1.9	0.9	-1.7	-1.9	-0.7
Diabetes (father)	1.7	2.1	7.4	-0.8	-0.9	-1.4	-1.1	-1.5	-1.6	0.8	0.4	-2.2	-2.7	-0.5
Body mass index (BMI)	1.7	7.4	14.5	-1.4	-2.1	-2.9	-3.8	-3.5	-3.6	1.8	0.6	-3.3	-3.4	-0.9
Overall health rating	1.7	3.7	11.4	-1.3	-2.2	-1.7	-1.9	-3.4	-3.1	1.1	0.7	-1.7	-1.4	-0.2
Breast cancer (self-reported)	1.7	2.0	4.1	1.2	1.9	1.4	1.3	0.7	2.0	-1.8	-1.7	1.3	1.0	-0.6
Schizophrenia (2018)	1.6	3.4	7.4	1.2	1.4	2.7	2.7	-1.1	0.9	-2.5	-1.0	2.2	2.3	-0.1
Relative age of first facial hair	1.6	3.2	5.6	-1.7	-1.8	-1.9	-1.9	-0.7	-1.1	2.3	1.7	-2.4	-1.9	1.8
Blood Red Count	1.5	14.2	23.1	-4.2	-4.7	-4.6	-4.8	0.3	-3.5	2.5	4.5	-4.1	-3.7	1.6
Frequency of depressed mood in last 2 weeks	1.5	2.1	3.6	-1.9	-1.8	-1.4	-1.6	0.0	0.3	1.8	1.5	-1.4	-1.2	1.6
High blood pressure (mother)	1.5	2.0	5.6	-1.3	-1.8	-1.9	-1.5	0.0	-1.1	2.4	1.0	-1.5	-0.9	0.8
Qualifications: O levels/GCSEs or equivalent	1.5	2.3	5.4	-1.7	-1.6	-1.2	-1.0	-0.5	-1.1	1.2	1.9	-1.8	-2.3	1.6
Medication: Allopurinol	1.5	2.0	4.7	1.4	2.2	1.7	1.0	0.4	1.3	-1.6	-2.1	1.1	0.9	-0.9
Pulse rate, automated reading	1.5	4.7	9.0	-1.7	-2.6	-2.8	-3.0	-0.2	-3.0	2.3	2.7	-1.6	-1.1	-0.1
Guilty feelings	1.5	2.2	5.8	0.1	1.5	1.7	1.9	-2.4	1.2	-1.6	-2.0	0.8	0.2	1.1
Bipolar Disorder or Schizophrenia	1.4	3.4	8.0	1.2	1.5	2.8	2.5	-1.3	1.1	-1.8	-1.5	2.2	2.4	-0.2
Primary Biliary Cirrhosis	1.4	1.9	5.7	-0.1	-1.9	-1.2	-1.5	-0.0	-1.2	2.4	1.5	-1.2	-0.9	-1.5
Schizophrenia (2014)	1.4	3.0	7.9	0.9	1.2	2.8	2.3	-0.5	1.7	-1.9	-1.0	2.1	2.3	-0.1
Number of treatments/medications taken	1.4	2.5	5.2	-1.5	-2.1	-1.7	-2.3	-1.1	-1.3	1.4	0.5	-2.1	-2.0	0.3
Medication: Co-codamol	1.4	1.6	2.7	-1.5	-1.3	-1.1	-1.4	-1.2	-1.3	0.7	1.1	-1.7	-1.4	0.8
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	4.8	1.2	1.4	1.2	1.2	0.1	2.2	-0.4	-1.6	1.1	0.6	-1.2
Had menopause	1.4	1.7	6.3	-1.8	-0.9	-1.4	-2.5	0.5	0.5	1.2	0.1	-1.3	-1.1	1.3
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	4.5	-2.1	-1.8	-1.4	-1.7	-0.4	-0.3	1.4	1.4	-0.7	-0.9	1.5
Weight	1.4	6.8	14.6	-2.5	-1.9	-2.8	-3.8	-2.6	-2.8	2.6	0.7	-3.1	-3.2	0.1
Gout (self-reported)	1.4	2.0	3.3	0.9	1.5	1.5	1.3	1.6	1.5	-1.6	-1.8	1.4	1.4	-0.3
Migraine (self-reported)	1.4	1.8	3.8	-1.2	-1.4	-1.4	-1.9	-0.8	-0.3	1.7	-0.0	-1.6	-2.0	0.4
Chest pain or discomfort	1.4	2.0	13.3	-0.6	-0.7	-0.0	-0.2	-3.6	-1.6	0.2	0.4	-1.2	-1.9	-0.1
Age at First Birth	1.3	1.9	5.0	1.4	1.0	1.3	1.7	1.6	2.2	-0.5	0.2	1.6	1.0	-1.1
Mouth/teeth dental problems	1.3	2.0	9.2	0.9	0.8	1.4	0.9	2.0	3.0	-1.0	0.0	1.3	1.2	-0.4
Noisy workplace	1.3	1.6	5.1	-1.2	-2.2	-1.5	-1.2	-0.1	-0.6	1.4	0.7	-1.5	-1.3	1.0
Exposure to tobacco smoke outside home	1.3	1.8	4.8	-1.8	-1.7	-1.4	-0.9	0.1	-1.2	0.1	2.2	-0.7	-0.6	1.9
Average weekly beer plus cider intake	1.3	1.9	6.0	-1.6	-1.7	-1.7	-1.4	-1.1	0.6	2.5	0.7	-1.3	-0.7	0.6
Triglycerides	1.2	2.0	7.0	-1.7	-2.6	-1.4	-0.9	-0.4	-0.0	1.0	2.3	-0.8	-1.0	1.1
Health satisfaction	1.2	1.6	6.6	0.1	-1.2	-0.9	-0.8	-2.6	-1.9	0.6	0.9	-0.8	-1.0	-1.1
Medication: Seretide 50 evohaler	1.2	1.3	3.8	-1.3	-0.1	-0.9	-1.5	-2.0	-1.0	1.1	0.3	-1.4	-1.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.6	7.6	-1.8	-2.3	-1.4	-1.0	1.6	-0.2	1.7	2.8	-0.6	-0.4	1.7
Commuting to job workplace: Walk	1.2	1.3	3.5	-0.8	-1.3	-1.9	-0.9	-0.4	-0.5	1.3	1.3	-1.4	-1.0	0.5
Medication: Aspirin	1.2	1.5	5.9	-0.8	-2.4	-1.4	-1.1	-0.1	-0.7	1.5	1.2	-1.2	-1.1	-0.1
Illnesses of father: None of the above (group 1)	1.2	1.5	3.2	1.6	1.8	1.4	1.1	1.4	0.1	-1.0	-0.9	1.3	0.8	-1.4
Ever taken oral contraceptive pill	1.2	1.3	7.0	-0.6	-0.2	-0.2	-0.8	-2.6	-2.0	0.7	0.4	-0.7	-1.2	0.1
Age started oral contraceptive pill	1.2	1.5	5.7	0.9	2.3	0.9	0.3	0.6	1.4	-1.1	-2.4	0.3	-0.1	-0.7
LDL Cholesterol	1.1	1.7	5.7	1.4	0.2	0.5	2.1	0.7	2.4	-1.5	-0.0	1.4	1.4	-0.3
Neuroticism	1.1	2.6	6.9	-1.7	0.9	-0.3	-1.2	-2.6	0.8	-0.4	-1.5	-1.6	-2.2	2.5
Supplements: Glucosamine	1.1	1.4	3.2	-0.9	-0.7	-1.4	-1.8	0.4	-0.9	1.2	0.8	-1.8	-1.8	-0.2
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	2.9	-1.5	-1.0	-0.1	-0.9	-1.7	-1.4	0.8	0.9	-1.1	-1.4	1.1
Alzheimer’s Disease (in mother)	1.0	1.1	2.6	0.3	1.4	1.6	1.4	0.7	1.3	-0.5	-0.7	1.2	1.3	0.2
Medication for hormone replacement therapy	1.0	1.1	3.7	0.5	1.5	1.4	0.3	0.8	0.9	-1.9	-1.4	0.8	0.2	0.4
Diabetes (mother)	1.0	1.2	2.2	-1.4	-1.5	-1.1	-1.2	-0.4	-1.1	0.8	0.2	-1.3	-1.1	1.4
Serious illness, injury or assault to yourself	1.0	1.2	3.9	-1.2	-2.0	-0.6	-0.4	-1.0	-0.6	0.9	2.0	-0.5	-0.6	0.8
Number of live births	1.0	1.4	3.8	-0.4	-1.7	-1.6	-0.7	-0.9	-1.4	0.9	1.9	-0.8	-0.8	-0.7
Medication: Ibuprofen	1.0	1.2	2.3	1.2	1.0	1.5	1.0	0.5	1.4	-0.7	-1.4	0.9	0.7	-1.5
Illnesses of father: High blood pressure	1.0	1.2	3.3	-0.7	-0.7	-1.1	-0.4	-1.8	-0.5	1.0	0.9	-1.7	-1.7	0.4
Ever had prostate specific antigen (PSA) test	1.0	1.1	2.9	0.7	1.7	0.9	1.6	-0.2	-0.1	-1.5	-1.7	0.6	0.2	0.3
Medication: Atenolol	0.9	1.2	3.1	-0.9	-1.3	-1.3	-0.7	-0.5	-0.5	0.8	1.1	-1.8	-1.5	0.3
Shortness of breath walking on level ground	0.9	1.0	4.1	-0.2	-1.0	0.1	-0.3	-2.0	-0.6	0.8	-1.7	-1.0	-0.9	-0.7
Knee pain experienced in last month	0.9	1.4	3.7	-1.2	-0.8	-1.0	-1.4	-1.9	-1.7	0.4	0.4	-1.2	-1.5	0.3
Smoking status: Previous	0.9	1.3	4.6	-0.5	1.8	0.3	0.2	-2.2	-1.0	-1.0	-1.2	-0.1	-0.2	1.6
Loneliness, isolation	0.9	1.2	2.5	-1.6	-1.1	-0.9	-0.9	-1.3	0.9	1.1	-0.3	-1.1	-1.0	1.3
Friendships satisfaction	0.9	1.1	4.1	1.2	0.5	0.2	0.2	-1.4	0.3	0.5	-0.6	-0.9	-1.7	-2.0
Arm fat-free mass (left)	0.9	4.8	13.8	-2.5	-1.0	-2.2	-3.7	-1.0	-1.8	1.9	0.6	-2.8	-3.2	1.0
Alcohol drinker status: Previous	0.9	1.0	5.9	-1.0	-0.4	-0.9	-1.0	0.9	-2.4	0.7	0.6	-0.7	-0.4	0.0
Arm predicted mass (left)	0.9	4.3	12.7	-2.3	-1.1	-2.1	-3.6	-0.8	-1.7	1.9	0.5	-2.6	-3.0	0.9
Verbal and Numeric Reasoning (VNR)	0.8	1.9	5.8	-1.7	-1.9	-1.0	-0.9	0.8	-1.3	-0.3	2.4	-1.2	-1.3	1.0
Relative age voice broke	0.8	1.2	2.8	-0.8	-0.8	-1.5	-0.7	-0.7	-0.5	0.9	1.1	-1.5	-1.7	1.1
Past tobacco smoking	0.8	1.4	4.1	1.3	-0.4	0.9	0.9	2.0	1.9	-0.2	0.0	0.9	0.9	-1.7
Had other major operations	0.8	0.9	3.0	-1.1	-0.7	-1.0	-1.0	-1.7	-0.4	0.7	0.3	-1.1	-1.2	0.6
Lung cancer (father)	0.8	0.9	2.5	-1.0	-0.2	-0.9	-1.6	0.1	-0.8	0.5	0.8	-1.3	-1.5	0.2
Arm fat-free mass (right)	0.8	4.1	13.2	-2.4	-1.1	-2.0	-3.6	-0.3	-1.3	1.6	0.8	-2.6	-2.8	1.3
Worry too long after embarrassment	0.8	1.3	3.1	0.6	1.7	1.4	0.6	-1.0	1.3	-1.7	-1.7	0.5	0.1	0.2
Eye problems/disorders: None of the above	0.8	0.9	2.1	-0.4	-0.1	-1.0	-1.1	-1.3	-1.0	1.0	-0.6	-1.2	-1.4	-0.1
Heart disease (mother)	0.8	1.0	3.0	-0.7	-1.0	-1.2	-0.8	-1.7	-1.0	0.6	0.2	-1.2	-1.0	0.1
Arm predicted mass (right)	0.8	3.9	12.8	-2.3	-0.9	-1.9	-3.6	-0.4	-1.2	1.6	0.7	-2.6	-2.8	1.0
Age at last live birth	0.8	1.1	2.1	1.3	1.2	1.3	1.1	1.4	1.2	-0.4	-0.5	0.9	0.6	-1.1
Back pain experienced in last month	0.8	1.1	6.1	0.7	0.6	0.3	-0.1	-2.5	-1.1	-0.2	-1.4	-0.1	-0.5	-1.3
Myopia	0.8	1.2	3.7	0.3	0.2	0.7	1.9	0.8	1.3	-1.2	0.3	1.5	1.4	0.7
Neuroticism (Nagel 2018)	0.7	1.6	5.1	-1.2	1.0	0.4	-0.2	-1.9	1.3	-0.9	-1.2	-0.9	-1.2	2.3
Reaction Time	0.7	1.4	3.5	-1.1	-1.8	-1.5	-1.7	0.5	-0.6	1.9	0.9	-1.0	-0.3	0.3
Angina	0.7	0.9	1.9	0.0	-1.2	-0.5	-0.6	-1.4	-1.3	0.5	0.8	-1.2	-1.2	-0.4
Alcohol intake versus 10 years previously	0.7	1.0	2.1	-1.0	0.1	-1.3	-1.4	0.6	-0.5	1.4	-0.8	-1.2	-0.9	0.9
Worrier / anxious feelings	0.7	1.4	2.5	-1.5	-0.5	-0.5	-1.3	-1.6	0.9	0.8	-1.0	-1.6	-1.3	1.4
Glaucoma (self-reported)	0.7	0.8	4.2	0.5	1.1	-0.4	-0.1	-2.0	-0.6	0.3	-0.8	-0.7	-0.9	-0.5
Angina (self-reported)	0.7	0.9	1.8	-0.2	-1.2	-0.6	-0.7	-1.3	-1.4	0.5	0.7	-1.3	-1.2	-0.1
Supplements: Vitamin C	0.7	0.8	2.9	-1.3	-0.3	-0.9	-0.4	0.5	0.0	-0.2	1.4	-0.7	-1.0	1.7
Financial situation satisfaction	0.7	0.8	2.3	1.1	1.0	0.9	1.3	0.1	1.1	-0.6	-1.5	0.4	-0.1	-0.8
Commuting to job workplace: Public transport	0.7	0.9	2.2	-1.1	-0.2	-1.3	-0.7	-0.1	-0.3	0.8	1.5	-0.7	-0.8	1.4
Eye problems/disorders: Glaucoma	0.7	0.8	3.2	1.2	1.0	0.4	0.4	-1.0	0.5	-0.6	-1.1	0.0	-0.1	-1.8
Medication: Bendroflumethiazide	0.7	1.1	3.4	-0.8	-1.6	-1.0	-1.0	0.0	-0.0	1.0	1.0	-1.4	-1.8	-0.0
Fractured/broken bones in last 5 years	0.7	0.9	2.3	0.8	0.9	0.9	0.7	-1.5	0.6	-0.8	-1.5	0.7	0.9	-0.9
Supplements: Calcium	0.7	0.8	2.3	-0.9	-1.3	-1.2	-0.5	0.9	0.6	0.5	0.9	-0.1	0.0	1.5
Alzheimer’s Disease (including proxy)	0.6	0.9	2.0	0.3	1.0	1.4	1.4	0.0	0.6	-0.1	-0.8	1.4	1.1	0.4
Blood Eosinophil Count	0.6	4.5	17.1	-3.1	-1.9	-1.6	-0.5	-4.1	-1.7	2.0	-0.7	-1.4	-1.3	2.2
Heel T-Score	0.6	4.7	13.2	3.6	1.8	1.8	1.1	3.3	1.4	-2.3	-1.8	0.8	0.6	-2.9
Average weekly spirits intake	0.6	0.7	3.1	-0.4	0.1	-0.3	-0.6	-1.8	0.5	0.3	-0.6	-1.2	-1.4	-0.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.4	-0.6	-0.9	-1.1	-0.8	-0.7	0.1	1.2	-0.0	-0.9	-1.1	0.5
Average weekly fortified wine intake	0.6	0.7	2.5	0.6	0.1	0.9	1.2	-1.1	0.4	-0.2	-1.6	0.7	0.6	-0.1
Fed-up feelings	0.6	1.2	2.6	-1.5	-0.7	-0.4	-1.0	-1.6	-0.2	-0.1	0.4	-1.3	-1.3	1.6
Sitting height	0.6	4.1	10.0	0.5	2.2	2.5	1.9	3.0	3.2	-0.7	-1.3	2.3	1.9	0.6
Nervous feelings	0.6	1.0	4.4	0.7	0.8	0.7	0.5	-1.3	2.1	-1.4	-1.1	0.3	0.2	0.0
Illnesses of siblings	0.6	0.9	3.7	1.0	0.5	0.3	0.1	1.9	-0.5	-0.0	1.1	0.8	1.1	-1.1
Neuroticism score	0.6	1.2	3.1	-1.2	0.7	0.4	-0.5	-1.7	1.4	-0.8	-1.1	-0.6	-0.9	1.6
Falls in the last year	0.6	0.8	4.5	-0.6	-0.2	-0.3	-0.6	-2.1	0.1	0.5	-0.7	-0.9	-1.2	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.4	-0.8	-0.6	0.5	0.3	0.2	-0.2	-0.2	1.6	0.9	1.4	0.7
Medication: Lansoprazole	0.6	0.6	1.7	-1.3	-1.2	-0.8	-0.6	-0.5	0.1	1.0	0.2	-0.6	-0.7	0.7
Length of working week for main job	0.6	0.7	4.6	-0.2	0.5	0.7	-0.0	2.2	1.4	0.1	0.1	0.2	0.5	0.0
Loud music exposure frequency	0.6	0.7	1.5	0.1	0.9	1.2	0.9	-0.4	0.9	0.3	-1.0	-0.6	-1.1	-0.6
High blood pressure (siblings)	0.6	0.9	3.1	0.1	0.8	0.9	1.0	-1.8	-0.2	-1.4	-1.3	0.0	-0.3	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.5	1.6	0.5	0.8	0.6	1.1	-0.1	-0.9	0.1	0.7	0.6	-1.2
Had major operations	0.6	0.7	2.9	0.7	0.2	1.2	0.8	0.2	0.7	-0.9	-1.7	0.8	0.7	-0.5
Leg pain on walking	0.6	0.8	1.9	-0.1	-1.4	-0.9	-0.7	-0.3	-0.8	1.1	0.3	-1.0	-1.3	-0.8
Medication: Lisinopril	0.6	0.8	3.4	-1.0	-1.8	0.3	-0.2	1.1	0.3	0.4	1.4	0.3	0.3	1.1
Basal metabolic rate	0.6	3.1	8.0	-1.9	-0.8	-1.7	-2.8	-1.2	-1.4	1.6	0.4	-2.2	-2.7	0.5
Number of operations (self-reported)	0.6	0.9	2.9	-1.2	-1.7	-0.7	-0.8	-0.8	-0.9	0.7	0.7	-0.5	-0.9	0.9
Unable to work because of sickness or disability	0.6	0.7	5.0	-0.1	-2.2	-0.3	-0.1	-1.1	0.5	0.4	0.3	-0.5	-0.5	-1.0
Fasting Glucose	0.5	0.6	2.0	0.6	1.4	0.8	0.5	-1.0	-0.5	-1.0	-0.8	0.0	-0.4	-0.5
Height	0.5	10.3	36.1	-6.0	-1.9	-2.9	-3.0	1.1	-1.4	3.7	2.3	-1.8	-1.7	5.2
Vitamin and mineral supplements	0.5	0.6	3.2	0.5	0.6	0.4	0.3	-1.8	-0.5	0.0	-1.1	0.3	0.5	-0.9
Supplements: Zinc	0.5	0.6	3.7	0.1	0.1	-1.1	0.0	-0.6	1.9	0.5	-0.4	-0.6	-0.5	0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.5	0.9	-0.4	-0.8	-1.0	-0.2	-0.5	0.5	0.4	-1.8	-1.9	-1.4
Impedance of leg (left)	0.5	2.4	6.1	-2.1	-2.5	-2.1	-0.7	0.2	-1.2	2.2	1.9	-0.8	-0.0	0.9
Hearing difficulty/problems with background noise	0.5	0.9	1.8	-1.2	-0.3	-1.1	-1.1	-0.4	0.5	0.4	0.1	-1.2	-1.1	1.3
Time employed in main current job	0.5	0.5	2.6	0.3	1.1	0.5	0.1	-0.3	1.1	-0.3	-1.6	0.2	0.5	-0.0
Pulse rate	0.5	0.8	2.4	0.6	-1.2	-1.2	-0.9	0.7	-1.1	-0.1	0.4	-0.3	-0.3	-1.5
Happiness	0.5	0.6	2.5	0.2	-0.4	-0.2	-0.7	-1.0	-0.6	0.5	0.5	-1.1	-1.6	-0.8
Prospective memory result	0.5	0.6	2.0	0.0	-0.4	1.0	1.0	0.2	0.3	-0.9	0.4	1.2	1.4	0.5
Breastfed as a baby	0.5	0.6	1.4	-0.4	-0.5	-0.9	-0.3	-1.2	-1.2	0.9	1.1	-0.2	-0.7	0.5
Pulse wave reflection index	0.5	0.7	2.3	0.2	1.5	-0.1	0.2	-1.1	0.3	-0.5	-1.5	0.1	0.2	0.9
Medication: Amlodipine	0.5	0.7	3.4	-1.3	-0.5	-0.2	-1.0	0.2	0.1	-0.1	0.6	-0.6	-0.8	1.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.7	-0.1	-0.2	-0.1	0.1	-1.6	-0.5	0.7	-1.0	-0.8	-0.7	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.0	-0.3	-0.9	-0.9	-0.8	0.1	-0.7	0.7	1.0	-0.7	-1.0	-0.4
Average weekly red wine intake	0.5	0.7	2.0	-0.1	0.5	0.0	-0.4	-1.3	-0.5	-0.2	-1.3	-1.4	-1.3	-0.2
Mood swings	0.5	0.8	3.4	-1.8	-0.5	0.2	-0.7	-1.3	-0.0	0.4	0.3	-0.7	-0.9	1.4
Ever had bowel cancer screening	0.5	0.5	1.0	-0.9	0.3	-0.8	-0.7	-0.5	-0.4	0.6	-1.0	-0.9	-0.9	0.7
Mineral and other dietary supplements	0.5	0.6	1.1	0.6	0.5	0.8	0.7	-1.1	-0.9	-0.9	-1.0	0.7	1.0	-0.3
Osteoporosis (self-reported)	0.5	0.6	1.7	0.7	0.6	1.1	0.6	-1.3	-0.3	-1.1	-0.3	0.6	0.4	-0.6
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.7	-0.8	0.3	0.1	0.0	-1.4	-0.4	-0.1	-0.6	-0.5	-0.6	1.6
Supplements: Fish oil (including cod liver oil)	0.5	0.7	1.1	-0.3	-0.7	-1.0	-0.6	0.9	1.0	0.9	1.0	-0.7	-1.0	-0.4
High cholesterol (Self-reported)	0.5	0.9	3.6	0.8	-1.9	-0.9	0.5	-1.1	0.8	0.8	0.6	-0.0	0.2	-1.4
Medication: Atorvastatin	0.5	0.6	1.8	0.6	-1.4	-0.6	0.1	0.6	-0.4	1.2	0.8	-0.5	-0.4	-1.0
Ever smoked	0.5	0.9	2.7	-1.0	0.0	-0.7	-0.7	-1.5	-1.6	0.6	0.1	-0.6	-0.6	1.5
Bipolar Disorder (2018)	0.4	0.7	1.4	0.5	1.2	1.2	0.6	-0.3	0.7	-0.8	-1.2	0.8	0.9	-0.1
Depressed Affect (Nagel 2018)	0.4	0.9	2.9	-1.4	0.3	0.2	-0.5	-1.1	0.6	-0.6	-0.7	-0.8	-0.9	1.7
Worry (Nagel 2018)	0.4	0.9	2.9	0.1	1.2	0.4	-0.4	-1.5	1.1	-0.7	-1.7	-0.6	-0.7	0.8
Breast Cancer	0.4	1.0	2.5	-0.6	-1.6	-1.0	-1.5	1.4	0.2	1.3	0.4	-0.9	-0.5	0.3
Body Mass Index (BMI) (2010)	0.4	0.6	2.8	-1.1	-0.5	0.6	-0.6	-0.7	-0.8	-0.4	0.5	-0.0	-0.1	1.7
Chronotype (morning person)	0.4	0.9	4.5	-0.4	-1.3	-0.9	-0.8	0.6	-2.1	-0.5	0.7	-0.7	-0.4	0.9
Hair Pigment	0.4	10.8	20.1	-4.5	-2.7	-3.9	-3.4	-3.2	-3.3	2.7	1.8	-3.1	-2.8	4.0
Sensitivity / hurt feelings	0.4	0.6	2.6	-0.7	-0.7	0.1	0.3	-0.5	1.4	-0.5	0.9	-0.1	-0.5	1.6
Ever had hysterectomy (womb removed)	0.4	0.4	1.5	-0.6	-0.1	-0.7	-0.4	-0.0	1.2	-0.2	0.2	-0.8	-0.8	0.8
Impedance of leg (right)	0.4	1.8	5.1	-1.9	-2.3	-1.5	-0.2	0.1	-1.3	1.5	1.8	-0.3	0.4	1.0
Hand grip strength (right)	0.4	1.2	3.2	-1.4	-1.5	-0.5	-0.2	1.3	1.7	0.1	0.9	-0.3	-0.4	1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	3.2	0.1	-0.8	-1.1	-1.3	0.8	-0.2	0.5	0.9	-1.5	-1.8	-0.2
Fluid intelligence score	0.4	0.8	6.4	-0.2	-0.4	-0.0	-0.3	2.5	-0.2	-0.8	1.1	0.2	0.2	-0.2
Father’s age at death	0.4	0.5	2.0	-0.7	0.6	-0.4	-0.1	1.3	0.7	-0.6	-0.4	0.1	0.2	1.4
Impedance of arm (left)	0.4	1.7	7.9	0.7	-0.1	0.7	2.8	-0.1	1.0	0.3	0.3	1.8	2.2	-0.5
Tense / ‘highly strung’	0.4	0.7	1.4	-0.3	0.7	-0.1	-0.9	-1.1	1.1	0.6	-0.9	-1.2	-1.1	0.2
Medication: Paracetamol	0.4	0.6	1.5	0.9	0.5	-0.2	-1.2	0.5	-1.1	-0.2	-0.1	-0.8	-0.5	-1.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.7	0.2	1.6	1.0	0.4	0.9	-0.4	-0.2	-0.6	1.1	0.9	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	3.2	0.9	-1.0	-0.1	0.2	0.6	0.8	-0.2	-0.1	-0.2	0.3	-1.8
Mean time to correctly identify matches	0.4	0.7	2.1	-0.6	-1.0	-1.3	-1.4	-0.1	0.0	1.2	0.4	-0.9	-0.2	-0.0
Comparative height size at age 10	0.4	2.4	4.7	0.4	1.5	2.2	1.5	1.6	1.4	-1.4	-1.5	2.1	2.0	-0.7
Family relationship satisfaction	0.4	0.5	2.1	-0.4	-0.3	-0.1	-0.3	-1.3	-0.5	0.3	0.1	-1.0	-1.4	-0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.7	-0.0	-0.5	0.6	-0.3	-0.6	-1.1	0.2	-1.3	-0.4	-0.5	-0.8
Handedness (chirality/laterality): Left-handed	0.4	0.4	1.1	-0.8	-0.1	-0.6	-0.6	-0.9	-0.2	0.7	0.5	-0.4	-0.6	1.1
Medication: Gliclazide	0.4	0.5	1.5	-0.3	-1.2	-0.2	-0.4	-1.2	-0.8	0.3	-0.2	-0.6	-0.7	-0.5
Average weekly champagne plus white wine intake	0.4	0.5	2.8	1.1	1.7	0.5	0.2	0.2	0.3	-0.4	-0.4	0.5	0.2	-0.9
Medication: Paracetamol	0.4	0.6	1.7	0.9	0.9	0.5	0.0	1.3	0.2	-1.0	-0.5	0.4	0.9	-1.0
Risk taking	0.4	0.7	2.6	0.0	0.5	0.4	0.6	1.6	0.2	0.0	0.4	1.3	1.3	0.0
Basal cell carcinoma (self-reported)	0.4	0.5	2.1	-0.7	-0.2	0.3	0.5	0.9	1.5	0.0	0.6	0.6	0.6	0.7
Schizophrenia vs Biploar Disorder	0.3	0.4	2.5	-0.8	-0.5	0.2	0.2	0.7	0.0	0.0	1.6	-0.3	-0.3	0.1
Alzheimer’s Disease (in father)	0.3	0.4	0.9	-0.5	-0.8	-0.5	-0.6	0.3	-0.6	0.9	0.8	-0.1	-0.5	0.3
Type 2 Diabetes (T2D) (2012)	0.3	0.3	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.2	-1.5	0.2
Hypothyroidism (self reported)	0.3	0.7	2.6	-0.0	0.7	0.7	0.1	-0.6	0.5	-1.6	-1.4	-0.3	-0.5	0.9
Lung FEV1/FVC ratio	0.3	1.7	7.4	-0.4	-0.6	-2.0	-2.7	-0.1	-0.5	1.8	-0.3	-1.2	-1.0	-0.8
Hand grip strength (left)	0.3	0.8	2.6	-1.3	-1.4	-0.5	-0.0	0.6	0.9	-0.1	1.1	-0.4	-0.4	1.6
Hearing difficulty/problems: Yes	0.3	0.4	0.9	-0.8	0.8	-0.1	-0.2	-1.0	0.8	-0.4	-0.6	-0.3	-0.6	1.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.9	-0.3	0.3	-0.2	-0.4	-0.5	0.7	-0.0	-1.4	-0.5	-0.6	0.4
Leg fat-free mass (left)	0.3	1.7	4.5	-1.2	-0.4	-1.0	-2.0	-1.4	-0.9	1.3	0.5	-1.7	-2.1	0.2
Townsend deprivation index at recruitment	0.3	0.4	0.9	-0.6	-0.5	-1.0	-0.2	-0.8	0.7	0.9	-0.9	-0.4	-0.1	0.6
Age when periods started (menarche)	0.3	0.8	5.0	0.0	-0.4	-0.4	0.6	2.2	1.0	0.7	0.5	0.7	0.9	0.5
Stomach or abdominal pain in last month	0.3	0.3	1.5	0.8	0.8	0.8	0.3	-0.0	-0.1	-0.1	-0.4	0.1	-0.3	-1.2
Leg predicted mass (left)	0.3	1.7	4.3	-1.2	-0.4	-1.0	-2.0	-1.4	-0.9	1.3	0.4	-1.6	-2.1	0.1
Alcohol usually taken with meals	0.3	0.5	2.2	0.8	1.4	0.5	-0.1	0.0	-0.5	0.0	-1.5	-0.3	-0.4	-0.3
Qualifications: None of the above	0.3	0.7	1.7	0.9	0.1	0.6	-0.2	-1.3	-1.0	-0.4	-1.2	0.5	0.9	-1.2
Heart attack	0.3	0.4	1.0	1.0	0.1	0.9	0.8	-0.7	0.5	-0.9	-0.0	0.3	0.2	-0.6
Medication: Simvastatin	0.3	0.4	2.3	-0.6	-1.5	-0.5	0.2	-0.8	-0.1	-0.0	0.5	0.0	0.1	0.6
Impedance of arm (right)	0.3	1.4	7.7	0.5	-0.3	0.4	2.8	-0.3	0.2	0.6	0.3	1.6	2.0	-0.6
Medication: Cholesterol lowering	0.3	0.5	1.6	0.1	-1.1	-1.0	0.2	-1.2	0.4	0.5	0.3	-0.7	-0.8	-0.4
Exposure to tobacco smoke at home	0.3	0.4	1.8	0.5	0.3	0.0	-0.1	-1.3	-0.2	-1.0	-0.4	-0.0	0.5	-0.9
Peak expiratory flow (PEF)	0.3	0.6	4.4	1.0	0.4	0.1	0.3	2.1	1.0	-0.2	-0.4	0.3	0.1	-0.5
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.3	-0.3	-0.7	0.1	0.1	-1.1	-0.6	0.4	-0.1	-0.9	-1.1	0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	1.3	-0.2	1.0	-0.4	0.6	-0.6	0.2	-0.1	-0.2	0.4	0.3	1.1
Comparative body size at age 10	0.3	1.0	3.5	0.8	0.7	0.9	0.5	0.8	-0.5	-0.3	-1.1	1.1	1.9	-1.3
Neck or shoulder pain in last month	0.3	0.4	1.1	0.1	-0.5	-0.5	-0.6	-1.1	-1.0	-0.3	-0.9	-0.5	-0.6	-0.4
Medication: Blood pressure	0.3	0.6	2.0	-0.6	-1.4	-0.6	-0.9	-0.1	-0.4	-0.1	0.9	-1.0	-0.8	0.2
Whole body fat-free mass	0.3	1.7	5.5	-1.5	-0.2	-1.1	-2.3	-0.5	-0.7	1.0	0.2	-1.7	-2.2	0.7
Leg fat-free mass (right)	0.3	1.5	4.5	-1.0	-0.2	-1.0	-1.9	-0.9	-0.5	1.4	0.3	-1.7	-2.1	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.8	-0.2	0.2	-0.1	0.1	1.3	0.6	0.7	0.2	-0.1	-0.4	-0.6
Qualifications: nursing, teaching	0.3	0.5	1.6	0.6	-0.8	-0.7	0.0	0.7	1.3	0.6	1.2	-0.2	-0.3	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.8	0.3	0.3	-0.5	-0.9	-0.3	0.5	0.8	0.6	-0.3	-0.7	-0.6
Whole body water mass	0.3	1.7	5.6	-1.4	-0.1	-1.0	-2.4	-0.6	-0.7	1.0	0.1	-1.7	-2.2	0.6
Leg predicted mass (right)	0.3	1.6	4.8	-1.1	-0.2	-1.0	-2.0	-1.0	-0.5	1.4	0.3	-1.7	-2.2	-0.0
Miserableness	0.3	0.5	2.5	-1.6	-0.4	0.2	-0.8	-0.4	0.3	0.7	0.2	-0.5	-0.6	1.0
Wears glasses or contact lenses	0.3	0.3	1.1	-0.4	0.1	0.1	0.6	-0.6	1.1	-0.8	-0.1	0.2	-0.3	1.1
Hearing aid user	0.3	0.4	0.8	-0.3	0.3	-0.5	-0.5	-0.9	0.7	-0.4	-0.9	-0.5	-0.8	-0.7
Mother’s age at death	0.3	0.4	1.6	0.6	0.9	-0.2	0.0	0.6	1.3	-0.1	-0.8	-0.0	-0.0	-0.8
Cholesterol lowering medication	0.3	0.5	2.8	-0.5	-1.7	-0.9	-0.3	0.2	0.4	0.8	0.8	-0.2	-0.2	0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	1.0	0.1	0.9	0.8	-0.7	0.5	-0.9	-0.1	0.4	0.3	-0.6
Heart disease (siblings)	0.3	0.3	0.9	-0.5	-0.5	-0.3	-0.6	0.7	0.9	0.8	0.0	-0.4	-0.6	0.6
Intelligence (Savage-Jansen 2018)	0.2	0.7	3.7	0.2	0.1	0.9	0.6	1.1	-0.0	-1.9	0.6	0.8	0.4	-0.4
Coronary Artery Disease (CAD)	0.2	0.2	1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	1.4	0.4
Lupus	0.2	0.3	1.6	-0.3	-0.7	0.1	-0.3	-0.2	-1.3	0.7	0.5	-0.8	-0.4	-0.2
Neuroticism (2016)	0.2	0.4	0.8	-0.5	0.5	0.1	-0.6	-0.3	0.9	-0.8	-0.5	-0.5	-0.8	0.6
Waist Hip Ratio (WHR)	0.2	1.1	3.1	-1.6	-1.4	-1.8	0.1	-1.3	-0.6	-0.6	0.8	-0.5	-0.6	0.9
Multivitamins +/- minerals	0.2	0.3	1.3	-0.2	-0.2	0.2	0.1	1.1	1.0	-0.1	0.5	0.2	0.3	0.7
Trunk fat-free mass	0.2	1.3	4.6	-1.5	0.1	-0.8	-2.1	0.1	-0.4	0.6	-0.0	-1.4	-2.0	0.9
Hair/balding pattern: Pattern 3	0.2	0.3	0.8	0.0	0.4	-0.1	-0.7	-0.6	-0.9	-0.5	-0.6	-0.7	-0.7	-0.7
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	0.9	0.5	-0.5	0.5	-0.5	-1.2	-0.4	1.2	-0.1	-0.5	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.6	0.3	0.4	0.5	-0.1	-0.2	-0.3	0.4	-0.8	-0.4	-0.6	-0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.6	-0.3	0.6	-0.6	-0.2	-0.7	-0.1	0.1	-0.4	0.3	0.3	0.8
Trunk predicted mass	0.2	1.4	4.8	-1.5	-0.0	-0.8	-2.2	0.1	-0.4	0.7	0.0	-1.4	-2.0	0.9
Standing height	0.2	1.8	6.3	-2.5	0.1	-0.4	-0.6	1.7	1.0	2.0	0.6	-0.0	-0.4	2.2
Hair/balding pattern: Pattern 4	0.2	0.5	2.3	-0.3	1.1	-0.2	-0.6	-0.6	-0.8	0.0	-1.5	-0.8	-0.1	0.3
Birth weight of first child	0.2	0.3	1.0	-0.5	0.9	-0.2	-0.5	-0.9	-1.0	-0.0	0.1	-0.1	-0.5	0.1
Headache pain in last month	0.2	0.3	0.9	0.3	0.3	0.4	-0.8	0.4	-0.5	0.7	-0.3	0.1	-0.3	-1.0
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.6	-0.2	0.3	0.2	-0.4	-0.6	0.5	-1.3	-1.0	-0.3	-0.1	1.0
Number of full brothers	0.2	0.2	0.8	-0.7	-0.4	-0.1	0.5	-0.9	-0.1	-0.8	0.1	0.1	-0.2	0.4
Number of children fathered	0.2	0.3	1.1	0.4	-0.2	0.0	-0.1	-0.6	-0.7	0.2	-0.4	-0.3	-1.0	-0.8
Pulse wave peak to peak time	0.2	0.2	0.6	-0.0	-0.7	0.5	0.2	0.8	0.3	0.1	0.6	-0.4	-0.5	-0.4
Alcohol intake frequency.	0.2	0.4	1.6	0.2	-0.1	-0.0	-0.5	0.6	-0.1	1.3	-0.8	-0.1	0.3	-1.1
Number of full sisters	0.2	0.2	0.6	-0.5	-0.8	-0.5	-0.2	-0.3	-0.4	-0.4	0.7	-0.3	-0.5	0.1
Suffer from ‘nerves’	0.2	0.3	1.4	-0.2	0.2	-0.0	-0.2	-1.1	1.2	0.4	0.3	0.1	0.1	0.6
Illnesses of father: Heart disease	0.2	0.2	0.8	-0.1	-0.2	0.6	0.8	-0.1	0.5	-0.3	-0.0	0.3	0.4	0.9
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.0	-0.5	-0.5	-0.3	-1.0	-0.5	0.1	0.4	0.6	0.3	0.1	0.0
Alcohol drinker status: Never	0.2	0.3	1.1	0.6	-0.1	-0.4	-0.2	0.3	0.8	0.4	-0.4	0.1	0.4	-1.0
Ever depressed for a whole week	0.2	0.2	0.7	-0.1	0.5	0.9	-0.3	-0.4	-0.7	-0.4	-0.1	-0.3	-0.7	0.1
Impedance of whole body	0.2	1.0	2.4	-0.7	-1.2	-0.5	1.4	0.2	0.2	1.3	1.1	0.8	1.5	0.3
Mean Putamen Volume	0.1	0.1	0.8	0.3	-0.0	-0.3	0.1	-0.9	0.4	-0.0	-0.5	-0.2	0.2	-0.2
HbA1C	0.1	0.1	0.3	0.2	-0.5	-0.2	0.2	0.5	0.3	0.3	-0.5	0.2	0.5	0.3
Tanning	0.1	1.6	6.0	1.2	2.4	1.4	0.8	0.4	-1.2	-1.4	-1.4	0.1	-0.4	-1.4
Medication: Levothyroxine sodium	0.1	0.2	1.1	-0.2	-0.5	-0.1	-0.6	-0.2	-0.1	-0.6	0.4	-0.1	-0.1	1.0
Blood clot in the leg (DVT)	0.1	0.1	0.4	0.0	0.1	0.6	-0.3	-0.2	-0.6	0.2	0.4	0.2	0.1	-0.6
Birth weight	0.1	0.2	0.4	0.1	0.6	-0.0	0.5	-0.4	-0.6	-0.4	0.3	0.6	0.6	0.3
Osteoarthritis (self-reported)	0.1	0.2	1.0	-0.3	-0.2	-0.2	-1.0	-0.5	-0.2	0.1	-0.5	-0.1	-0.1	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.5	-0.2	0.2	0.7	-0.2	0.1	-0.3	0.3	0.6	0.3	0.2	-0.4
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

STMN3

Models

Trait associations