TWAS hub - CNIH2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Muscularis	0.0600	0.0290	0.0056	0.016	NA	0.012	NA	0.018	0.036	NA	0.0580	NA	0.028
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0259	0.0157	0.0050	0.005	0.009	0.015	NA	0.007	0.089	0.029	0.0064	NA	0.052

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Fed-up feelings	11.8	21.4	22.8	4.5	4.8
Average weekly red wine intake	10.6	15.7	26.9	-2.1	-5.2
Overall health rating	9.5	20.3	21.1	4.6	4.4
Qualifications: A levels/AS levels or equivalent	9.1	20.1	22.6	-4.2	-4.8
Long-standing illness, disability or infirmity	9.1	13.9	15.2	3.9	3.6
Qualifications: College or University degree	8.3	26.1	37.1	-3.9	-6.1
Supplements: Fish oil (including cod liver oil)	8.3	10.9	14.5	-2.7	-3.8
Breast Cancer	7.5	18.0	23.5	-3.5	-4.8
Leg fat percentage (right)	7.5	27.3	28.0	5.2	5.3
Leg fat mass (right)	7.5	29.2	29.5	5.4	5.4
Mood swings	7.5	13.6	15.0	3.9	3.5
Depressed Affect (Nagel 2018)	7.0	14.8	16.4	4.0	3.6
Whole body fat mass	7.0	29.4	32.7	5.1	5.7
Schizophrenia vs Biploar Disorder	6.8	9.0	11.6	3.4	2.5
Leg fat percentage (left)	6.7	24.4	25.8	4.8	5.1
Trunk fat mass	6.6	28.3	33.6	4.8	5.8
Waist circumference	6.6	24.2	25.7	5.1	4.8
Leg fat mass (left)	6.6	26.0	26.3	5.1	5.1
Commuting to job workplace: Cycle	6.5	7.8	13.3	-1.5	-3.6
Lung cancer (father)	6.4	7.5	8.1	2.9	2.6
Body fat percentage	6.3	24.8	28.2	4.6	5.3
Cholesterol lowering medication	6.3	9.3	11.8	2.6	3.4
Mineral and other dietary supplements	6.1	8.2	10.6	2.4	3.3
Supplements: Glucosamine	6.0	7.8	10.2	-2.3	-3.2
Bipolar Disorder (2011)	5.9	5.7	11.4	-3.4	0.0
Maternal smoking around birth	5.8	8.3	13.2	3.6	1.9
Alcohol usually taken with meals	5.8	9.3	11.9	-2.6	-3.4
Trunk fat percentage	5.7	22.7	27.2	4.3	5.2
Handedness (chirality/laterality): Left-handed	5.7	6.9	9.5	-3.1	-2.1
Pain experienced in last month	5.5	9.2	10.3	-3.2	-2.9
Alcohol intake frequency.	5.4	12.6	17.6	2.7	4.2
Arm fat mass (right)	5.3	22.0	22.3	4.7	4.7
Weight	5.2	25.6	28.0	4.8	5.3
Arm fat mass (left)	5.2	21.2	21.3	4.6	4.6
Back pain experienced in last month	5.1	7.5	7.7	2.7	2.8
Bipolar Disorder (2018)	4.9	7.8	15.1	-3.9	-0.6
Vitamin and mineral supplements	4.9	6.7	13.1	0.5	3.6
Qualifications: None of the above	4.8	10.3	11.5	3.0	3.4
BMI	4.2	24.3	29.3	5.4	4.4
Diabetes diagnosed by doctor	4.2	6.9	8.9	3.0	2.2
Arm fat percentage (left)	4.1	16.2	16.7	4.1	4.0
Pack years adult smoking proportion	4.0	6.1	8.4	2.0	2.9
Body mass index (BMI)	4.0	16.9	22.2	4.7	3.4
Frequency of tiredness / lethargy in last 2 weeks	4.0	6.5	7.7	2.8	2.3
Average weekly beer plus cider intake	4.0	5.7	9.5	1.4	3.1
Chronotype (morning person)	3.9	8.9	16.8	4.1	1.0
Triglycerides	3.8	6.3	12.6	3.5	0.0
Type 2 Diabetes (T2D) (2018)	3.8	7.0	9.0	3.0	2.3
Arm fat percentage (right)	3.8	15.1	15.9	4.0	3.8
Illness, injury, bereavement, stress in last 2 years	3.8	4.6	4.8	-2.1	-2.2
Qualifications: nursing, teaching	3.6	5.5	8.9	-1.5	-3.0
Multivitamins +/- minerals	3.5	4.5	8.7	-0.4	-3.0
Medication: Blood pressure	3.5	6.7	7.3	2.5	2.7
Pack years of smoking	3.5	5.1	8.1	1.5	2.8
Hip circumference	3.4	14.6	16.7	3.5	4.1
Health satisfaction	3.4	4.4	6.5	2.5	1.5
Diabetes (self-reported)	3.3	5.1	6.3	2.5	2.0
Supplements: Calcium	3.3	3.6	4.5	-1.7	-2.1
Had major operations	3.2	3.8	4.8	1.7	2.2
Supplements: Vitamin C	3.2	3.8	6.3	-1.2	-2.5
Diverticular disease/diverticulitis (self-reported)	3.1	3.6	7.2	-0.2	-2.7
Medication: Levothyroxine sodium	3.1	5.2	5.7	2.2	2.4
Qualifications: O levels/GCSEs or equivalent	3.1	4.9	6.6	-2.6	-1.8
Waist Hip Ratio (WHR)	3.0	13.4	18.9	4.3	2.8
Medication: Metformin	3.0	4.2	5.7	2.4	1.6
Serious illness, injury or assault to yourself	3.0	3.6	4.1	2.0	1.8
Commuting to job workplace: Public transport	3.0	3.6	6.5	-0.8	-2.6
Arm predicted mass (left)	3.0	15.3	15.4	3.9	3.9
Arm fat-free mass (right)	2.9	15.0	15.1	3.9	3.9
Arm fat-free mass (left)	2.9	14.9	15.1	3.9	3.9
Bipolar Disorder or Schizophrenia	2.8	6.8	11.3	-3.4	-1.5
Severe depression (siblings)	2.7	3.0	3.5	-1.6	-1.9
Mouth/teeth dental problems: Dentures	2.7	4.6	8.5	0.8	2.9
Number of operations (self-reported)	2.7	4.0	5.4	2.3	1.6
Medication: Seretide 50 evohaler	2.6	3.0	3.6	1.5	1.9
Arm predicted mass (right)	2.6	13.5	13.7	3.7	3.7
Basal metabolic rate	2.6	14.2	14.4	3.7	3.8
Reason for reducing amount of alcohol drunk: Health precaution	2.5	2.9	3.5	-1.6	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.2	9.7	0.9	3.1
Number of incorrect matches in round	2.4	4.0	8.0	-0.2	-2.8
Exposure to tobacco smoke outside home	2.4	3.2	4.9	1.2	2.2
Breast cancer (self-reported)	2.4	2.9	4.3	1.2	2.1
Financial difficulties in last 2 years	2.3	3.1	4.8	1.2	2.2
Father’s age at death	2.3	3.1	3.3	-1.8	-1.7
Age at last live birth	2.3	3.3	4.4	-2.1	-1.5
Medication for cholesterol	2.3	3.5	3.5	-1.9	-1.9
Miserableness	2.3	4.0	5.6	2.4	1.5
Mother’s age at death	2.3	2.9	3.2	-1.8	-1.6
Neuroticism (Nagel 2018)	2.2	5.1	5.3	2.2	2.3
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	3.0	1.7	1.4
Neck or shoulder pain in last month	2.2	3.1	5.8	0.6	2.4
Prostate Cancer	2.1	3.0	3.6	-1.5	-1.9
Allergy or Eczema	2.1	5.5	9.3	-1.3	-3.0
Leg fat-free mass (left)	2.1	10.9	11.5	3.4	3.2
Townsend deprivation index at recruitment	2.1	2.9	3.2	1.8	1.6
Leg predicted mass (left)	2.0	10.7	11.4	3.4	3.2
Noisy workplace	2.0	2.4	2.8	1.4	1.7
Hypothyroidism/myxoedema (self-reported)	2.0	4.0	4.3	2.1	1.9
Smoking status: Current	2.0	3.1	3.3	1.7	1.8
Whole body fat-free mass	1.9	10.8	10.9	3.3	3.3
Whole body water mass	1.9	10.6	10.8	3.3	3.2
Frequency of depressed mood in last 2 weeks	1.8	2.5	3.5	1.9	1.2
Age at first live birth	1.8	3.3	3.8	-1.7	-1.9
Shortness of breath walking on level ground	1.8	2.2	3.0	1.7	1.2
Hypothyroidism (self reported)	1.7	3.9	4.9	2.2	1.7
Other serious medical condition/disability diagnosed by doctor	1.7	2.3	3.1	1.8	1.2
Current tobacco smoking	1.7	2.8	3.6	1.4	1.9
Average weekly fortified wine intake	1.7	2.0	3.0	-1.1	-1.7
Trunk fat-free mass	1.7	9.7	10.4	3.0	3.2
Asthma	1.7	3.4	5.2	2.3	1.3
Trunk predicted mass	1.7	9.9	10.8	3.0	3.3
Blood clot in the leg (DVT)	1.7	2.2	2.2	1.5	1.5
Suffer from ‘nerves’	1.7	2.7	4.4	-2.1	-1.0
Asthma (self-reported)	1.7	3.3	5.1	2.2	1.2
Lung FVC	1.6	8.2	14.7	-1.3	-3.8
Had other major operations	1.6	2.0	2.7	1.6	1.1
Medication: Allopurinol	1.6	2.1	2.3	1.4	1.5
Primary Biliary Cirrhosis	1.5	2.1	2.6	1.6	1.3
Ever had hysterectomy (womb removed)	1.5	1.6	1.7	1.2	1.3
Medication: Co-codamol	1.5	1.7	3.4	-0.3	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	2.4	1.5	1.3
Qualifications: CSEs or equivalent	1.5	2.0	2.1	1.4	1.4
Hearing difficulty/problems with background noise	1.5	2.4	2.4	-1.5	-1.6
Alcohol intake versus 10 years previously	1.5	2.2	2.8	1.3	1.7
Gout (self-reported)	1.5	2.0	2.5	1.2	1.6
High cholesterol (Self-reported)	1.5	2.6	4.3	1.0	2.1
Alzheimer’s Disease (in mother)	1.4	1.6	3.0	-0.4	-1.7
Major Depression (MDD)	1.4	1.7	1.9	-1.4	-1.2
Taking other prescription medications	1.4	2.2	2.8	1.7	1.2
Bilateral oophorectomy (both ovaries removed)	1.4	1.7	1.7	1.3	1.3
Stomach or abdominal pain in last month	1.4	1.7	3.5	1.9	0.0
Knee pain experienced in last month	1.4	2.1	2.5	1.3	1.6
Illnesses of siblings: Diabetes	1.4	1.8	3.0	1.7	0.7
Leg fat-free mass (right)	1.4	7.5	8.1	2.9	2.6
Leg predicted mass (right)	1.4	7.5	8.1	2.8	2.6
Depression (Nagel 2018)	1.3	1.9	3.0	1.7	0.9
Height	1.3	24.2	43.4	2.2	6.6
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	2.7	-1.6	-0.7
Depression (self-reported)	1.3	1.6	2.3	-1.5	-0.9
Prospective memory result	1.3	1.6	2.5	0.9	1.6
Pulse wave Arterial Stiffness index	1.3	1.5	1.8	1.1	1.3
Standing height	1.3	13.0	24.7	1.1	5.0
Length of working week for main job	1.3	1.4	2.5	0.6	1.6
Number of self-reported non-cancer illnesses	1.3	2.3	4.1	2.0	0.8
HDL Cholesterol	1.2	1.9	3.9	-2.0	0.0
Smoking Status	1.2	2.8	3.2	1.8	1.6
Neuroticism	1.2	2.9	3.6	1.5	1.9
Sensitivity / hurt feelings	1.2	2.0	2.9	1.7	1.1
Sitting height	1.2	8.3	9.5	2.6	3.1
Neuroticism score	1.2	2.5	2.5	1.6	1.6
Hair/balding pattern: Pattern 3	1.2	1.9	1.9	-1.4	-1.3
Breastfed as a baby	1.2	1.5	1.9	-1.0	-1.4
Headache pain in last month	1.2	2.1	2.4	1.4	1.5
Illnesses of father: None of the above (group 1)	1.2	1.4	2.8	0.3	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	4.1	-0.9	-2.0
Myopia	1.2	1.7	3.4	0.2	-1.8
Hayfever, allergic rhinitis or eczema	1.1	2.3	4.6	-0.3	-2.1
Hair/balding pattern: Pattern 4	1.1	2.7	2.9	-1.7	-1.6
Peak expiratory flow (PEF)	1.1	2.5	2.7	-1.6	-1.5
Leg pain on walking	1.1	1.4	2.3	1.5	-0.7
Osteoarthritis (self-reported)	1.1	1.4	2.7	-0.5	1.6
Deep venous thrombosis (DVT) (self-reported)	1.1	1.5	1.9	1.0	1.4
Alzheimer’s Disease (in father)	1.0	1.1	1.4	1.2	0.9
Verbal and Numeric Reasoning (VNR)	1.0	2.4	4.2	0.8	2.0
Hearing difficulty/problems: Yes	1.0	1.5	1.9	-1.4	-1.1
Hand grip strength (right)	1.0	2.8	4.1	1.2	2.0
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	3.0	1.3	-1.7
Mouth/teeth dental problems	1.0	1.6	2.6	0.8	-1.6
Eye problems/disorders: None of the above	1.0	1.1	1.7	-1.3	-0.7
Comparative height size at age 10	1.0	5.2	10.4	0.3	3.2
Loneliness, isolation	1.0	1.4	1.6	1.0	1.3
Commuting to job workplace: Walk	1.0	1.0	1.5	-1.2	-0.8
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	3.2	-1.8	-0.0
Ever smoked	1.0	1.7	2.4	-1.1	-1.5
Schizophrenia (2018)	0.9	1.8	2.2	-1.2	-1.5
Diabetes (father)	0.9	1.2	2.3	1.5	-0.1
Pain all over the body in last month	0.9	1.0	1.4	1.2	0.8
Happiness	0.9	1.0	1.6	1.3	0.7
Glaucoma (self-reported)	0.9	1.0	1.6	0.7	-1.2
Mouth/teeth dental problems: Loose teeth	0.9	1.1	1.4	0.9	-1.2
Angina (self-reported)	0.9	1.2	2.2	0.5	1.5
Osteoporosis (self-reported)	0.9	1.1	1.6	1.3	0.8
Tinnitus: Yes, now most or all of the time	0.9	1.1	2.0	-0.3	1.4
Average weekly spirits intake	0.8	0.9	1.8	1.3	-0.3
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	1.9	-0.5	-1.4
Tense / ‘highly strung’	0.8	1.3	1.4	-1.1	-1.2
Wheeze or whistling in the chest in last year	0.8	1.4	1.9	1.4	1.0
Financial situation satisfaction	0.8	0.9	1.6	0.5	1.3
Medication: Bendroflumethiazide	0.8	1.3	2.5	-0.2	1.6
Medication: Atorvastatin	0.8	0.9	1.8	0.3	1.3
Lupus	0.7	1.1	2.1	-0.1	-1.5
Angina	0.7	1.0	1.6	0.5	1.3
Medication for hormone replacement therapy	0.7	0.8	1.6	0.0	-1.3
Diabetes (mother)	0.7	0.9	1.3	1.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	2.0	1.2	-1.4
Medication: Ramipril	0.7	0.9	1.6	1.3	-0.3
Medication: Simvastatin	0.7	1.0	1.8	0.3	1.4
Pulse rate	0.7	1.1	2.0	-0.5	-1.4
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.6	0.3	1.3
Medication: Amlodipine	0.7	1.0	2.0	1.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.1	-1.1	-0.7
Age started oral contraceptive pill	0.7	0.9	1.6	0.3	1.3
Unable to work because of sickness or disability	0.7	0.9	1.8	-0.0	1.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.6	-0.0	-1.3
Mean Putamen Volume	0.6	0.7	0.8	0.9	0.8
Number of children fathered	0.6	0.7	1.4	1.2	-0.0
Pulse wave peak to peak time	0.6	0.7	0.8	-0.9	-0.8
Emphysema/chronic bronchitis	0.6	0.7	1.4	-0.1	1.2
Medication: Blood pressure	0.6	1.1	1.7	-0.7	-1.3
Medication: Ibuprofen	0.6	0.8	0.9	-0.8	-0.9
Pulse rate, automated reading	0.6	2.0	3.5	1.9	0.7
Chest pain or discomfort	0.6	0.9	1.4	1.2	-0.7
Eye problems/disorders: Glaucoma	0.6	0.7	0.8	0.8	-0.9
Irritability	0.6	1.0	1.2	0.9	1.1
Ulcerative Colitis (UC)	0.5	0.9	1.7	-1.3	-0.4
Age at First Birth	0.5	0.7	1.4	-1.2	0.0
LDL Cholesterol	0.5	0.8	1.6	1.2	0.0
Ulcerative Colitis	0.5	0.7	1.4	-1.2	0.3
Heel T-Score	0.5	3.9	4.4	2.1	-1.8
Cardiovascular Disease	0.5	1.8	1.8	1.4	1.3
Hair Pigment	0.5	14.4	16.6	-4.1	-3.5
Impedance of leg (right)	0.5	2.3	4.5	-0.2	2.1
Relative age voice broke	0.5	0.8	1.3	-1.2	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	1.9	-1.4	-1.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.1	-1.1	-0.3
Migraine (self-reported)	0.5	0.6	1.0	1.0	0.5
Number of full sisters	0.5	0.6	1.2	0.1	1.1
Illnesses of father: Heart disease	0.5	0.7	1.4	-0.0	-1.2
Illnesses of father: High blood pressure	0.5	0.6	1.2	0.1	-1.1
HbA1C	0.4	0.4	0.7	0.8	0.5
Neuroticism (2016)	0.4	0.5	0.5	0.7	0.7
Respiratory disease	0.4	0.9	1.4	1.2	0.7
High blood pressure (mother)	0.4	0.6	1.3	0.1	-1.1
Impedance of leg (left)	0.4	1.9	3.1	-0.8	1.8
Past tobacco smoking	0.4	0.7	1.4	0.0	1.2
Impedance of arm (right)	0.4	1.7	3.4	-1.9	0.0
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	1.7	-1.3	-1.0
Impedance of arm (left)	0.4	1.8	3.5	-1.9	0.3
Pulse wave reflection index	0.4	0.5	0.9	-0.9	-0.4
Worry too long after embarrassment	0.4	0.7	1.0	1.0	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.9	-0.3	1.0
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.8	-0.5	0.9
Wears glasses or contact lenses	0.4	0.4	0.7	0.8	0.4
Hearing aid user	0.4	0.4	0.6	-0.5	-0.8
Risk taking	0.4	0.6	1.0	1.0	0.4
Ever depressed for a whole week	0.4	0.5	0.6	-0.8	-0.6
Worry (Nagel 2018)	0.3	0.6	0.7	-0.8	-0.7
Alzheimer’s Disease (including proxy)	0.3	0.5	0.9	1.0	0.0
Body Mass Index (BMI) (2010)	0.3	0.5	0.9	0.9	0.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.7	0.8	0.0
Blood Eosinophil Count	0.3	2.3	4.0	2.0	0.8
Blood White Count	0.3	2.0	2.4	1.3	1.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.4	-0.4	0.6
High blood pressure	0.3	0.8	0.9	0.9	0.9
Chronic bronchitis/emphysema (father)	0.3	0.4	0.5	0.5	-0.7
Worrier / anxious feelings	0.3	0.6	1.2	1.1	0.3
Medication: Lansoprazole	0.3	0.4	0.5	-0.5	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.6	0.4	0.8
Birth weight of first child	0.3	0.5	1.0	-0.2	-1.0
Birth weight	0.3	0.7	1.3	-0.2	1.1
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.7	0.8	0.2
Family relationship satisfaction	0.3	0.3	0.6	-0.8	0.2
Hypertension (Self-reported)	0.3	0.9	1.1	1.1	0.8
Friendships satisfaction	0.3	0.3	0.4	0.5	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.5	0.4	0.7
Alcohol drinker status: Never	0.3	0.4	0.5	-0.5	0.7
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.1	-0.6	-1.1
Heart disease (siblings)	0.3	0.4	0.4	-0.6	0.7
Alcohol drinker status: Previous	0.3	0.4	0.5	0.7	0.5
Impedance of whole body	0.3	1.6	1.6	-1.3	1.2
Crohns Disease (2017)	0.2	0.4	0.5	0.4	0.7
Coronary Artery Disease (CAD)	0.2	0.2	0.4	0.6	0.0
Rheumatoid Arthritis	0.2	0.2	0.4	0.3	0.6
Schizophrenia (2014)	0.2	0.5	1.0	-1.0	0.1
Tanning	0.2	2.4	4.5	2.1	0.5
Relative age of first facial hair	0.2	0.3	0.6	-0.8	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.5	0.3	0.7
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.3	-0.5	-0.3
Illnesses of siblings	0.2	0.3	0.3	-0.6	-0.5
Falls in the last year	0.2	0.2	0.3	0.4	-0.5
Medication: Cholesterol lowering	0.2	0.3	0.4	-0.6	0.4
Illnesses of mother	0.2	0.3	0.5	-0.7	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.4	0.6	-0.1
Medication: Gliclazide	0.2	0.2	0.3	-0.5	-0.5
Ever taken oral contraceptive pill	0.2	0.2	0.3	-0.6	0.3
Medication: Lisinopril	0.2	0.2	0.5	-0.7	-0.0
Fractured/broken bones in last 5 years	0.2	0.2	0.5	-0.2	-0.7
Intelligence (Savage-Jansen 2018)	0.1	0.4	0.5	-0.7	0.5
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	-0.6	0.2
Reaction Time	0.1	0.1	0.2	-0.5	-0.0
Ovarian Cancer	0.1	0.1	0.1	-0.4	-0.2
Crohns Disease (2012)	0.1	0.1	0.2	-0.1	0.4
Fasting Glucose	0.1	0.1	0.2	-0.0	-0.5
Blood Platelet Count	0.1	1.7	2.9	-0.8	-1.7
Blood Red Count	0.1	1.4	1.4	1.1	-1.2
Systolic Blood Pressure	0.1	0.4	0.5	0.4	0.7
Lung FEV1/FVC ratio	0.1	0.3	0.4	0.5	0.6
Hand grip strength (left)	0.1	0.1	0.2	0.5	-0.2
Number of treatments/medications taken	0.1	0.3	0.3	0.4	0.6
Systolic blood pressure, automated reading	0.1	0.2	0.4	-0.6	-0.3
Supplements: Zinc	0.1	0.1	0.1	-0.3	-0.4
Age when periods started (menarche)	0.1	0.3	0.5	-0.4	0.7
Hair/balding pattern: Pattern 2	0.1	0.2	0.3	0.3	0.5
Forced vital capacity (FVC)	0.1	0.3	0.4	-0.7	-0.2
Allergy	0.1	0.2	0.2	-0.4	0.4
Time employed in main current job	0.1	0.1	0.2	-0.4	0.0
Number of live births	0.1	0.1	0.2	-0.4	0.2
Exposure to tobacco smoke at home	0.1	0.1	0.1	0.3	-0.1
Loud music exposure frequency	0.1	0.1	0.1	0.2	0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.1	0.2	0.3
Forced vital capacity (FVC), Best measure	0.1	0.4	0.5	-0.7	-0.7
Comparative body size at age 10	0.1	0.4	0.4	0.5	0.7
Number of full brothers	0.1	0.1	0.3	-0.1	-0.5
Medication for pain relief, constipation, heartburn	0.1	0.1	0.3	0.1	0.5
Medication: Omeprazole	0.1	0.2	0.2	0.4	-0.4
Mean time to correctly identify matches	0.1	0.2	0.3	-0.5	0.2
Heart disease (mother)	0.1	0.2	0.3	0.6	0.1
Medication: Aspirin	0.1	0.1	0.1	0.3	0.3
Smoking status: Previous	0.1	0.2	0.3	-0.3	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.1	0.2	-0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	0.4	-0.2
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.1	0.3	0.1
Medication: Atenolol	0.0	0.1	0.1	-0.3	0.2
Nervous feelings	0.0	0.0	0.1	-0.3	-0.1
Had menopause	0.0	0.0	0.1	-0.2	-0.0
Heart attack	0.0	0.0	0.0	-0.1	0.1
Fluid intelligence score	0.0	0.0	0.1	-0.1	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.1	0.1	-0.2	0.3
Medication: Paracetamol	0.0	0.0	0.0	0.0	-0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.0	0.0	-0.1
High blood pressure (siblings)	0.0	0.1	0.1	0.2	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.1	0.1	-0.3	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.1	0.1	-0.3	-0.0
Ever had bowel cancer screening	0.0	0.0	0.1	0.1	0.3
Eye problems/disorders: Cataract	0.0	0.0	0.1	0.1	0.2
Medication: Aspirin	0.0	0.1	0.1	-0.0	-0.3
Average weekly champagne plus white wine intake	0.0	0.0	0.0	-0.2	0.1
Guilty feelings	0.0	0.1	0.1	-0.0	-0.3
Medication: Paracetamol	0.0	0.0	0.0	-0.1	-0.2
Diastolic blood pressure, automated reading	0.0	0.1	0.1	0.2	-0.3
Basal cell carcinoma (self-reported)	0.0	0.0	0.1	0.0	-0.3
Heart attack/myocardial infarction (self-reported)	0.0	0.1	0.1	0.2	0.3

Hub : Genes

CNIH2

Models

Trait associations