Hub : Genes

DPP3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0760	0.0310	8.1e-05	0.062	NA	0.043	NA	0.056	7.9e-06	NA	1.8e-04	NA	2.1e-05
2	GTEx	Adipose Visceral Omentum	0.1600	0.0590	1.2e-04	0.030	NA	0.054	NA	0.043	1.1e-02	NA	8.3e-04	NA	2.8e-03
3	GTEx	Artery Tibial	0.0707	0.0332	1.6e-03	0.038	NA	0.021	NA	0.027	5.8e-04	NA	8.5e-03	NA	3.2e-03
4	GTEx	Breast Mammary Tissue	0.1380	0.0630	9.9e-04	0.071	NA	0.030	NA	0.049	1.7e-04	NA	1.1e-02	NA	1.5e-03
5	GTEx	Breast Mammary Tissue (Male)	0.1389	0.1069	8.4e-02	-0.005	NA	-0.012	NA	-0.012	4.4e-01	NA	7.9e-01	NA	7.5e-01
6	GTEx	Cells Transformed fibroblasts	0.0660	0.0290	2.2e-03	0.062	NA	0.039	NA	0.067	2.0e-05	NA	6.2e-04	NA	9.2e-06
7	GTEx	Esophagus Mucosa	0.2490	0.0720	9.4e-08	0.096	NA	0.143	NA	0.132	5.8e-07	NA	8.1e-10	NA	4.1e-09
8	GTEx	Esophagus Muscularis	0.0600	0.0280	3.9e-03	0.082	NA	0.064	NA	0.066	1.1e-05	NA	1.0e-04	NA	7.7e-05
9	GTEx	Lung	0.0924	0.0355	9.9e-05	0.082	NA	0.071	NA	0.066	8.0e-07	NA	3.8e-06	NA	9.3e-06
10	GTEx	Muscle Skeletal	0.0401	0.0209	3.5e-03	0.054	NA	0.035	NA	0.047	5.3e-06	NA	2.1e-04	NA	1.9e-05
11	GTEx	Nerve Tibial	0.1914	0.0699	8.8e-06	0.110	NA	0.119	NA	0.106	3.6e-08	NA	9.5e-09	NA	5.9e-08
12	GTEx	Pancreas	0.1920	0.0610	2.1e-05	0.126	NA	0.141	NA	0.142	5.5e-06	NA	1.5e-06	NA	1.4e-06
13	GTEx	Skin Not Sun Exposed Suprapubic	0.0770	0.0380	6.8e-03	0.089	NA	0.058	NA	0.084	1.3e-05	NA	3.9e-04	NA	2.3e-05
14	GTEx	Skin Sun Exposed Lower leg	0.0790	0.0350	4.2e-04	0.078	NA	0.049	NA	0.067	4.8e-07	NA	6.0e-05	NA	3.4e-06
15	GTEx	Small Intestine Terminal Ileum	0.1530	0.0690	6.6e-03	0.023	NA	-0.008	NA	0.014	1.0e-01	NA	5.4e-01	NA	1.6e-01
16	GTEx	Stomach	0.1700	0.0760	8.6e-04	0.015	NA	0.041	NA	0.017	6.2e-02	NA	4.9e-03	NA	4.8e-02
17	GTEx	Testis	0.1010	0.0560	3.5e-03	0.059	NA	0.042	NA	0.069	1.3e-03	NA	5.9e-03	NA	5.3e-04
18	GTEx	Thyroid	0.0980	0.0410	1.5e-04	0.062	NA	0.065	NA	0.054	1.6e-05	NA	1.0e-05	NA	6.0e-05
19	METSIM	Adipose	0.0554	0.0212	3.4e-07	0.035	0.045	0.028	0.041	0.036	4.8e-06	2.6e-07	4.1e-05	6.8e-07	3.4e-06
20	YFS	Blood	0.0968	0.0253	0.0e+00	0.104	0.115	0.111	0.115	0.112	2.7e-32	1.7e-35	2.7e-34	1.1e-35	8.6e-35
21	TCGA	Bladder Urothelial Carcinoma	0.0270	0.0190	3.7e-03	0.028	0.019	0.012	NA	0.017	1.9e-03	9.5e-03	2.8e-02	NA	1.3e-02
22	TCGA	Cervical Squamous Cell Carcinoma	0.0460	0.0310	6.7e-03	0.016	0.022	0.014	NA	0.010	5.2e-02	2.7e-02	6.7e-02	NA	1.0e-01
23	TCGA	Kidney Renal Clear Cell Carcinoma	0.0492	0.0264	3.6e-07	0.064	0.064	0.064	NA	0.066	9.2e-08	9.9e-08	9.3e-08	NA	6.2e-08
24	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0540	0.0340	1.4e-03	0.069	0.054	0.060	NA	0.065	9.0e-05	4.6e-04	2.5e-04	NA	1.4e-04
25	TCGA	Prostate Adenocarcinoma	0.4794	0.4411	1.6e-14	0.141	0.138	0.134	NA	0.151	1.4e-14	2.6e-14	6.9e-14	NA	1.6e-15
26	TCGA	Thyroid Carcinoma	0.0710	0.0350	3.3e-09	0.087	0.104	0.095	NA	0.092	8.3e-09	2.4e-10	1.5e-09	NA	2.9e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Supplements: Fish oil (including cod liver oil)	12.2	15.9	23.9	-4.1	-4.9	-4.2	-4.1	-4.3	-3.9	0.3	-4.7	-4.2	-4.4	-3.9	-4.1	-4.1	-4.3	-4.7	-4.2	-2.5	-2.9	-2.7	-3.4	-4.6	-4.2	-4.0	-4.2	-3.9	-4.3
Overall health rating	8.3	17.9	27.2	5.0	4.1	4.7	5.1	4.5	3.4	2.9	4.1	4.6	1.5	4.2	4.5	4.4	4.5	4.6	3.0	0.4	4.9	4.1	3.2	4.5	5.2	4.6	4.5	4.9	4.9
Mineral and other dietary supplements	7.9	10.7	22.5	3.4	4.7	3.4	3.5	3.4	2.9	-0.3	3.8	3.4	3.4	3.3	3.4	3.3	3.5	3.8	3.2	1.9	2.4	1.9	3.0	3.8	3.4	3.2	3.4	3.2	3.4
Health satisfaction	7.8	10.2	15.3	3.7	2.6	3.5	3.6	3.4	2.8	2.3	3.2	3.4	1.5	3.1	3.7	3.3	3.3	3.2	3.0	-0.2	3.2	3.1	2.8	3.6	3.9	3.4	3.5	3.6	3.7
Supplements: Calcium	7.5	8.2	18.6	-3.0	-4.3	-3.3	-3.6	-2.9	-2.2	-0.8	-2.9	-2.9	-1.9	-2.7	-2.9	-3.3	-2.9	-3.4	-2.2	-0.7	-3.0	-2.1	-2.6	-3.2	-3.3	-3.0	-3.0	-3.0	-3.0
Seen doctor (GP) for nerves, anxiety, tension or depression	7.3	11.2	17.2	4.1	2.4	3.4	3.5	3.5	2.9	3.2	3.1	3.6	-0.4	2.5	3.7	3.2	3.5	3.4	3.5	-3.0	3.3	4.2	2.9	3.3	3.9	3.5	3.6	3.8	3.6
Asthma	6.5	12.8	19.4	4.1	2.4	3.9	3.2	3.8	4.0	2.7	3.5	3.9	0.4	2.7	3.9	3.6	3.8	3.9	3.8	-1.6	3.9	4.4	3.2	3.6	4.0	3.9	3.9	4.1	4.0
Forced expiratory volume in 1-second (FEV1)	6.4	21.6	32.9	-5.3	-4.3	-5.3	-5.7	-4.9	-3.8	-1.9	-5.0	-4.9	-1.1	-5.0	-5.7	-5.2	-4.9	-5.0	-4.0	-1.1	-4.4	-3.4	-4.3	-5.2	-5.4	-5.1	-5.2	-5.1	-5.1
Peak expiratory flow (PEF)	6.4	14.8	24.0	-4.5	-3.1	-4.2	-4.8	-4.1	-3.1	-1.0	-4.2	-4.1	-1.1	-4.7	-4.9	-4.2	-4.1	-4.2	-3.5	-1.4	-3.3	-2.6	-3.5	-4.3	-4.5	-4.2	-4.3	-4.2	-4.2
Forced vital capacity (FVC)	6.3	24.3	38.7	-5.6	-4.8	-5.6	-6.0	-5.3	-4.0	-1.6	-5.3	-5.2	-0.9	-5.2	-6.2	-5.5	-5.2	-5.2	-4.2	-0.8	-4.8	-3.5	-4.7	-5.5	-5.7	-5.4	-5.5	-5.3	-5.4
LDL Cholesterol	6.2	9.9	16.8	3.5	4.1	3.3	3.3	3.6	3.0	1.2	3.4	3.4	1.9	3.0	3.7	3.3	3.4	3.6	2.9	0.3	2.6	2.6	2.7	3.5	3.4	3.3	3.4	3.3	3.3
Asthma (self-reported)	6.1	12.1	19.1	4.0	2.3	3.8	3.1	3.7	3.9	2.4	3.4	3.8	0.7	2.5	3.9	3.6	3.7	3.9	3.6	-1.4	3.6	4.4	3.1	3.6	3.9	3.8	3.9	4.0	4.0
Average weekly red wine intake	6.0	8.9	32.3	-2.9	-3.8	-3.0	-3.1	-3.1	-2.6	0.0	-3.6	-3.1	-5.7	-3.6	-3.1	-2.7	-3.2	-3.0	-2.1	-3.5	-1.9	-0.5	-0.3	-3.5	-2.7	-2.7	-3.0	-2.5	-2.7
Commuting to job workplace: Cycle	5.7	6.9	12.5	-2.9	-2.3	-2.8	-3.4	-2.8	-1.8	-0.1	-3.1	-2.8	-3.5	-3.5	-2.9	-2.7	-2.8	-3.0	-1.0	-3.3	-1.9	-0.5	-0.6	-3.2	-2.8	-2.6	-2.8	-2.4	-2.6
Forced vital capacity (FVC), Best measure	5.6	20.6	32.0	-5.1	-4.8	-5.3	-5.4	-4.7	-3.6	-1.2	-4.8	-4.7	-0.9	-4.7	-5.7	-5.1	-4.7	-4.7	-4.2	-1.5	-4.5	-3.1	-4.2	-5.1	-5.3	-4.9	-5.2	-4.9	-5.0
Number of self-reported non-cancer illnesses	5.6	9.7	15.4	3.7	1.3	3.6	3.8	3.3	2.3	2.5	3.1	3.3	0.6	3.0	3.5	3.3	3.2	3.3	2.4	0.6	3.3	3.4	2.6	3.5	3.9	3.3	3.5	3.6	3.7
Respiratory disease	5.5	12.3	16.4	4.0	2.2	3.9	3.2	3.7	4.0	2.3	3.5	3.8	1.0	2.8	3.6	3.7	3.6	3.9	3.8	-0.9	3.7	4.1	3.2	3.7	3.9	3.9	3.9	4.1	4.0
Bipolar Disorder or Schizophrenia	5.4	13.3	31.9	4.0	1.3	3.6	3.1	3.6	3.4	4.2	2.9	3.7	-1.9	2.5	3.4	3.7	3.6	3.3	2.8	-4.5	4.5	5.7	4.5	3.2	4.0	3.6	3.5	4.1	3.9
Medication: Co-codamol	5.4	6.3	11.1	2.6	2.7	2.5	3.1	2.6	1.9	0.9	2.7	2.5	3.3	2.9	2.6	2.7	2.6	2.6	1.8	1.8	1.9	1.9	1.7	2.9	2.9	2.5	2.5	2.6	2.9
Forced expiratory volume in 1-second (FEV1), Best measure	5.4	17.2	25.6	-4.7	-4.2	-4.8	-5.1	-4.3	-3.3	-1.3	-4.5	-4.2	-1.1	-4.6	-5.0	-4.7	-4.3	-4.4	-3.6	-1.9	-4.0	-2.7	-3.8	-4.7	-4.8	-4.5	-4.7	-4.5	-4.6
Cholesterol lowering medication	5.4	8.0	10.9	3.1	3.2	3.3	3.3	2.9	2.4	1.9	3.0	3.0	1.2	3.1	3.1	3.2	3.0	3.0	1.8	1.7	3.1	2.2	2.3	3.1	3.1	3.0	3.1	3.0	3.0
Breast Cancer	5.2	12.4	31.1	-3.5	-5.6	-3.8	-3.5	-3.5	-3.2	-1.4	-4.1	-3.5	-4.1	-3.6	-3.6	-3.8	-3.5	-4.0	-2.7	-2.9	-3.5	-1.7	-2.6	-4.0	-3.4	-3.5	-3.7	-3.2	-3.4
Supplements: Glucosamine	5.1	6.6	13.6	-2.8	-3.7	-2.8	-3.1	-2.7	-2.1	-0.0	-3.0	-2.7	-1.9	-3.0	-2.7	-2.5	-2.8	-3.0	-2.1	-1.0	-2.0	-1.6	-2.1	-3.0	-2.7	-2.6	-2.8	-2.5	-2.5
Bipolar Disorder (2018)	4.9	7.7	16.1	3.1	1.2	2.9	2.6	2.7	2.5	2.9	2.1	2.8	-1.2	1.7	2.8	3.0	2.7	2.8	1.8	-3.4	3.4	4.0	3.4	2.5	3.1	2.8	2.8	3.1	3.0
Long-standing illness, disability or infirmity	4.6	7.0	10.4	3.0	2.5	2.8	3.1	2.7	2.0	2.5	2.6	2.8	1.2	2.6	2.6	2.7	2.6	2.8	2.3	1.4	2.7	2.4	2.3	2.9	3.2	2.8	2.8	3.0	3.1
Arm fat percentage (right)	4.5	17.7	26.4	5.0	4.1	4.7	4.9	4.4	3.6	3.7	3.9	4.5	1.4	3.1	4.6	4.5	4.3	4.4	3.0	-1.3	5.0	4.5	3.0	4.4	5.1	4.6	4.5	4.9	4.9
Frequency of tiredness / lethargy in last 2 weeks	4.4	7.1	10.8	3.1	2.1	2.9	3.3	2.8	2.1	1.1	2.7	2.8	1.0	3.0	2.9	2.9	2.8	3.0	2.7	0.9	2.7	2.5	1.9	2.9	3.2	2.8	2.8	2.9	3.0
Heart attack/myocardial infarction (self-reported)	4.3	5.5	7.2	-2.6	-2.0	-2.7	-2.5	-2.6	-2.4	-0.9	-2.5	-2.6	-1.2	-2.5	-2.5	-2.5	-2.7	-2.3	-2.6	0.9	-2.3	-2.4	-1.7	-2.6	-2.5	-2.5	-2.6	-2.5	-2.5
Lung FVC	4.1	20.7	44.0	-4.8	-5.5	-5.0	-6.6	-4.4	-2.0	-0.1	-5.0	-4.3	-4.6	-6.2	-5.8	-4.9	-4.4	-4.6	-3.1	-5.9	-3.0	0.2	-2.2	-5.3	-5.0	-4.6	-4.8	-4.1	-4.3
Hand grip strength (left)	4.1	10.9	20.5	-3.8	-3.0	-3.6	-3.6	-3.4	-2.8	-1.9	-3.1	-3.3	0.7	-2.9	-3.9	-3.5	-3.3	-3.8	-2.9	0.1	-3.7	-2.8	-4.5	-3.3	-3.8	-3.6	-3.5	-3.7	-3.7
Taking other prescription medications	4.1	6.3	9.7	3.0	0.9	2.8	3.0	2.7	1.8	2.6	2.4	2.6	0.2	2.4	2.9	2.5	2.5	2.9	2.0	0.7	2.7	2.4	2.5	2.6	3.1	2.7	2.7	2.9	3.0
Medication: Seretide 50 evohaler	3.9	4.5	8.8	2.1	1.8	2.4	2.5	2.3	2.0	-0.4	2.5	2.3	3.0	2.6	2.1	2.2	2.2	2.5	1.9	1.4	1.7	1.4	1.1	2.6	2.1	2.2	2.2	2.0	2.1
Arm fat percentage (left)	3.9	15.5	23.6	4.7	3.9	4.4	4.8	4.1	3.1	3.5	3.6	4.2	1.4	3.0	4.3	4.2	4.0	4.1	2.6	-1.1	4.7	4.1	2.5	4.1	4.9	4.3	4.2	4.5	4.5
Primary Biliary Cirrhosis	3.8	5.4	8.0	2.5	2.8	2.5	2.6	2.3	2.2	0.2	2.7	2.4	2.3	2.2	2.4	2.8	2.6	2.5	2.0	0.9	1.4	2.3	1.5	2.8	2.6	2.4	2.6	2.4	2.6
Heart attack	3.8	4.9	6.4	-2.4	-1.9	-2.5	-2.3	-2.4	-2.3	-0.9	-2.3	-2.5	-1.1	-2.3	-2.3	-2.3	-2.5	-2.1	-2.5	0.8	-2.1	-2.3	-1.6	-2.5	-2.4	-2.4	-2.5	-2.4	-2.3
Allergy	3.8	8.9	20.3	-3.3	-0.2	-3.1	-2.5	-3.1	-3.2	-2.8	-2.5	-3.2	1.3	-1.7	-2.8	-2.9	-3.1	-3.1	-2.8	2.7	-4.1	-4.5	-2.7	-2.7	-3.3	-3.2	-3.1	-3.5	-3.3
Ulcerative Colitis	3.7	5.4	9.8	2.5	1.6	2.3	2.2	2.5	2.5	2.0	2.2	2.5	0.3	1.8	2.7	2.6	2.4	2.4	1.5	-0.9	2.4	3.1	2.6	2.3	2.7	2.6	2.4	2.8	2.8
Birth weight of first child	3.5	6.3	9.2	-2.7	-2.0	-2.8	-2.9	-2.6	-2.1	-2.2	-2.6	-2.7	-0.2	-2.5	-2.5	-2.8	-2.6	-2.5	-2.2	-0.0	-2.9	-2.2	-3.0	-2.7	-2.9	-2.7	-2.7	-2.8	-2.8
Qualifications: NVQ or HND or HNC or equivalent	3.5	4.2	6.5	2.2	2.5	2.2	2.4	2.3	1.9	0.0	2.3	2.2	1.6	2.4	2.0	2.3	2.3	2.3	1.2	1.1	2.0	1.3	1.5	2.3	2.2	2.3	2.2	2.1	2.1
Blood Red Count	3.4	32.8	69.4	6.0	4.9	5.7	4.1	5.4	6.5	6.3	4.4	5.6	-3.7	2.4	5.5	5.6	5.5	5.6	5.2	-6.3	7.1	8.3	7.0	4.7	5.9	5.9	5.7	6.5	6.2
Number of treatments/medications taken	3.4	6.1	9.9	3.0	1.2	2.9	2.9	2.5	1.9	3.1	2.2	2.5	-0.5	1.7	2.8	2.7	2.4	2.6	1.7	0.3	2.9	2.5	2.4	2.6	3.1	2.6	2.7	2.9	2.9
Qualifications: nursing, teaching	3.4	5.2	12.2	-2.3	-3.5	-2.6	-2.5	-2.3	-2.0	-1.6	-2.6	-2.3	-1.5	-2.1	-2.4	-2.4	-2.2	-2.1	-2.1	-1.3	-2.6	-1.1	-2.3	-2.6	-2.3	-2.3	-2.5	-2.2	-2.4
Number of operations (self-reported)	3.3	5.0	7.2	2.5	2.2	2.4	2.2	2.3	2.2	1.2	2.5	2.4	1.8	1.7	2.7	2.4	2.5	2.5	2.2	-0.1	2.1	2.0	1.8	2.5	2.5	2.4	2.4	2.4	2.5
Alcohol usually taken with meals	3.2	5.2	9.9	-2.4	-2.5	-2.4	-2.7	-2.3	-1.6	-1.7	-2.7	-2.3	-3.2	-2.6	-2.6	-2.4	-2.3	-2.3	-1.4	-2.2	-1.7	-0.7	-1.5	-2.7	-2.5	-2.2	-2.4	-2.1	-2.6
Medication: Simvastatin	3.2	4.7	9.1	2.3	1.4	2.4	2.4	2.3	1.8	1.0	2.5	2.2	1.6	3.0	2.5	2.3	2.3	2.4	1.4	2.2	1.7	1.1	2.1	2.5	2.4	2.2	2.4	2.2	2.4
Bipolar Disorder (2011)	3.1	3.0	21.5	1.4	-0.9	1.0	0.6	1.1	1.2	2.6	0.3	1.3	-3.0	0.1	1.1	0.9	1.1	0.6	1.1	-4.6	2.5	2.7	2.1	0.6	1.3	1.3	1.1	1.6	1.3
High cholesterol (Self-reported)	3.1	5.6	9.2	2.5	1.6	2.5	2.2	2.5	2.4	1.3	2.6	2.5	1.0	3.0	2.8	2.4	2.6	2.3	2.2	2.5	2.1	1.5	2.2	2.6	2.5	2.4	2.6	2.5	2.6
Heart disease (siblings)	3.1	3.8	6.5	2.1	1.3	2.0	2.2	2.1	1.9	-0.1	2.2	2.0	2.3	2.1	2.0	2.5	2.0	2.1	1.2	0.9	1.3	2.0	1.1	2.3	2.2	2.2	2.0	2.1	2.3
Body mass index (BMI)	3.0	12.8	20.9	4.2	4.1	3.9	4.0	3.7	3.0	3.7	3.1	3.8	0.7	2.1	3.7	3.6	3.6	3.6	2.5	-1.9	4.5	4.6	2.2	3.6	4.3	3.8	3.8	4.1	4.1
Schizophrenia (2018)	2.9	6.0	16.2	2.6	0.7	2.3	1.9	2.4	2.3	3.0	2.0	2.5	-1.4	1.9	2.1	2.3	2.5	2.0	2.1	-3.0	3.0	4.0	3.0	2.1	2.6	2.3	2.3	2.7	2.6
Serious illness, injury or assault to yourself	2.9	3.5	6.1	2.0	1.5	1.9	2.0	2.1	1.8	1.2	2.3	2.1	1.1	2.5	2.2	1.4	2.2	1.6	2.0	0.9	1.9	1.0	1.8	2.2	2.1	1.9	2.0	2.0	2.0
Current tobacco smoking	2.8	4.6	7.4	2.3	2.6	2.2	1.7	2.4	2.7	1.9	2.5	2.5	1.0	1.6	2.1	2.3	2.4	2.1	2.6	0.4	2.1	1.9	2.1	2.3	2.0	2.3	2.3	2.1	2.2
Fed-up feelings	2.8	5.0	10.8	2.2	2.3	2.4	2.4	2.3	1.8	0.1	2.6	2.2	2.6	3.3	2.1	1.9	2.1	2.4	2.3	3.3	1.9	1.0	1.4	2.5	2.2	2.0	2.3	2.0	2.3
Number of incorrect matches in round	2.8	4.6	9.1	-2.5	-1.2	-2.3	-2.4	-2.2	-1.8	-1.3	-2.3	-2.3	-0.7	-2.6	-1.9	-2.1	-2.3	-2.6	-1.6	-3.0	-2.3	-0.6	-2.4	-2.2	-2.3	-2.2	-2.2	-2.1	-2.2
Height	2.7	52.0	98.0	-7.5	-6.0	-7.5	-6.0	-7.5	-8.4	-0.6	-6.7	-7.2	2.5	-4.1	-8.6	-7.7	-7.3	-7.2	-6.5	4.1	-8.0	-9.9	-9.4	-6.9	-7.9	-8.1	-7.8	-8.3	-8.2
Vitamin and mineral supplements	2.7	3.7	10.2	1.8	2.5	2.0	1.8	1.9	1.7	-0.9	2.2	1.9	3.2	2.7	1.8	1.8	1.9	2.1	1.6	2.1	1.1	0.4	1.6	2.1	1.8	1.8	2.0	1.7	1.9
High blood pressure (mother)	2.7	3.8	8.7	-1.9	-1.8	-1.9	-1.4	-2.1	-2.5	-1.4	-2.2	-2.1	-0.8	-1.6	-2.0	-1.9	-2.1	-2.0	-2.8	-0.3	-1.3	-1.5	-2.9	-2.1	-1.9	-2.0	-2.1	-2.0	-2.1
Number of full sisters	2.7	3.3	8.4	1.9	0.2	1.4	1.2	2.1	2.2	2.9	1.8	2.1	-0.9	1.2	1.8	1.2	2.0	1.4	2.3	-1.0	1.7	2.0	2.6	1.6	1.8	1.8	1.7	2.0	2.0
Suffer from ‘nerves’	2.7	4.3	11.4	-2.0	-3.4	-2.3	-2.3	-2.1	-1.8	-2.3	-2.2	-2.2	-1.4	-1.5	-1.9	-2.2	-2.1	-2.3	-1.6	-0.8	-2.2	-1.3	-1.5	-2.3	-2.1	-2.1	-2.1	-2.0	-2.1
Schizophrenia (2014)	2.6	5.8	12.8	2.8	1.0	2.4	2.1	2.4	2.2	3.0	2.1	2.6	-0.5	2.1	2.2	2.5	2.5	2.0	2.0	-2.2	3.0	3.6	2.7	2.3	2.6	2.3	2.4	2.6	2.7
Qualifications: A levels/AS levels or equivalent	2.6	5.8	10.1	-2.7	-3.2	-2.9	-2.6	-2.5	-2.1	-1.5	-2.8	-2.6	-1.6	-2.1	-2.3	-2.5	-2.5	-2.6	-2.3	-0.9	-2.4	-1.8	-1.7	-2.8	-2.5	-2.5	-2.8	-2.4	-2.5
Diabetes diagnosed by doctor	2.6	4.2	8.5	2.4	1.5	2.2	2.9	2.2	1.1	2.7	2.1	2.2	0.1	2.4	2.2	2.0	2.1	2.3	1.4	0.9	1.9	1.3	1.7	2.2	2.5	2.2	2.1	2.2	2.2
Financial difficulties in last 2 years	2.5	3.3	5.0	2.1	1.0	2.0	1.9	2.1	2.0	1.4	1.8	2.1	0.4	1.6	2.0	1.8	2.0	1.7	2.2	0.0	2.0	1.8	1.6	1.8	2.1	2.1	2.0	2.1	2.1
Fluid intelligence score	2.5	5.3	8.7	-2.4	-1.2	-2.3	-1.7	-2.6	-2.9	-2.3	-2.7	-2.6	-0.8	-1.8	-2.3	-2.1	-2.6	-2.1	-2.9	0.7	-2.3	-2.1	-2.7	-2.5	-2.3	-2.4	-2.6	-2.5	-2.5
Arm fat mass (right)	2.5	10.2	15.7	3.9	3.5	3.5	4.0	3.3	2.4	3.6	2.9	3.5	1.5	2.3	3.2	3.3	3.2	3.4	2.1	-0.8	4.0	3.3	1.6	3.3	4.0	3.4	3.4	3.6	3.7
Blood clot in the leg (DVT)	2.5	3.2	5.1	2.0	1.7	1.9	2.2	1.9	1.4	1.4	2.0	2.0	1.0	2.1	1.8	1.9	1.9	2.0	1.3	0.6	1.8	1.0	1.8	2.0	2.0	2.0	1.8	1.9	1.9
Birth weight	2.5	5.4	9.1	2.7	2.8	2.5	2.1	2.5	2.4	1.6	2.3	2.4	1.8	1.5	2.6	2.3	2.4	2.6	3.0	0.0	2.1	2.0	2.1	2.4	2.6	2.4	2.5	2.5	2.6
Medication: Allopurinol	2.5	3.3	16.8	-1.7	-1.4	-1.2	-1.0	-1.4	-1.7	-1.9	-1.0	-1.5	2.0	0.2	-1.6	-1.5	-1.4	-1.7	-1.8	4.1	-1.6	-2.9	-2.9	-1.0	-1.7	-1.5	-1.3	-1.8	-1.7
Comparative height size at age 10	2.5	13.6	26.3	-3.8	-3.9	-4.0	-3.5	-3.7	-3.8	0.2	-3.3	-3.6	1.4	-2.0	-4.2	-4.1	-3.7	-3.7	-3.1	2.8	-4.2	-5.1	-4.2	-3.6	-4.1	-4.0	-4.1	-4.2	-4.0
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.6	5.2	1.6	1.1	1.5	1.2	1.3	1.4	2.2	1.1	1.4	-2.0	-0.1	1.4	1.7	1.4	1.4	1.4	-2.2	2.0	2.3	2.2	1.3	1.6	1.6	1.6	1.8	1.6
Intelligence (Savage-Jansen 2018)	2.4	7.3	9.0	-3.0	-2.4	-2.6	-2.6	-3.0	-2.9	-2.8	-2.8	-3.0	0.1	-2.0	-2.9	-2.7	-3.0	-2.9	-2.6	1.5	-2.6	-2.8	-3.0	-2.8	-2.9	-2.8	-2.9	-3.0	-2.9
Nervous feelings	2.4	4.5	8.5	-2.1	-2.2	-2.2	-1.8	-2.1	-2.3	-2.9	-1.7	-2.1	0.2	-1.0	-1.8	-2.3	-2.0	-2.0	-2.0	1.3	-2.7	-2.7	-2.5	-1.9	-2.3	-2.2	-2.0	-2.4	-2.4
Standing height	2.4	24.1	53.6	-5.1	-4.1	-5.2	-4.1	-5.1	-5.5	-0.2	-4.5	-4.9	1.8	-2.6	-5.9	-5.2	-5.0	-4.6	-4.2	4.1	-5.4	-7.3	-5.8	-4.7	-5.4	-5.3	-5.3	-5.6	-5.5
Leg fat percentage (right)	2.4	8.7	15.1	3.4	3.9	3.3	3.4	3.1	2.5	2.5	3.1	3.2	2.5	2.9	3.0	3.1	3.0	2.8	2.3	0.9	3.3	2.1	1.3	3.3	3.3	3.1	3.2	3.1	3.2
Wheeze or whistling in the chest in last year	2.4	4.3	7.7	2.5	1.4	2.2	2.0	2.2	2.0	2.3	1.8	2.3	-0.6	1.4	2.1	2.0	2.1	2.2	1.6	-1.9	2.4	2.8	1.8	2.0	2.4	2.2	2.2	2.4	2.3
Shortness of breath walking on level ground	2.4	2.9	4.5	2.1	1.4	1.7	1.7	1.8	1.6	1.7	1.3	1.8	-0.5	1.1	1.8	1.6	1.6	1.9	1.9	-0.9	2.1	2.0	1.4	1.6	2.0	1.8	1.8	2.0	1.9
Impedance of leg (left)	2.3	11.0	37.1	-3.5	-2.6	-3.1	-2.8	-2.9	-2.8	-3.3	-2.0	-2.9	2.8	0.5	-3.0	-2.9	-2.9	-3.3	-2.1	5.5	-4.3	-6.1	-3.1	-2.4	-3.7	-3.2	-3.0	-3.8	-3.6
Other serious medical condition/disability diagnosed by doctor	2.2	2.9	5.3	2.0	1.0	1.8	1.9	1.7	1.3	2.3	1.4	1.7	-0.4	1.3	1.7	1.5	1.7	1.6	1.2	-0.8	2.2	2.3	1.6	1.6	2.2	1.7	1.7	2.0	2.1
Hand grip strength (right)	2.2	6.0	14.6	-2.6	-1.2	-2.5	-2.1	-2.4	-2.6	-1.5	-2.1	-2.4	1.5	-1.8	-2.8	-2.5	-2.4	-2.6	-2.4	1.5	-2.8	-3.0	-3.8	-2.2	-2.7	-2.6	-2.5	-2.8	-2.7
Bilateral oophorectomy (both ovaries removed)	2.2	2.5	5.3	1.7	2.3	1.8	1.3	1.6	1.8	1.3	1.9	1.6	1.5	0.7	1.6	1.7	1.6	1.8	1.4	-0.1	1.7	1.2	1.5	1.8	1.5	1.6	1.7	1.6	1.7
Multivitamins +/- minerals	2.2	2.8	8.9	-1.6	-2.2	-1.6	-1.3	-1.7	-1.7	0.9	-2.0	-1.7	-3.0	-2.2	-1.7	-1.3	-1.7	-1.7	-1.5	-1.7	-0.8	-0.4	-1.5	-1.8	-1.5	-1.5	-1.6	-1.4	-1.6
Hayfever/allergic rhinitis (self-reported)	2.2	2.9	7.8	1.7	0.2	1.5	1.5	2.0	2.1	-0.5	1.7	1.9	1.0	1.4	1.5	2.0	1.9	2.0	1.7	-0.4	1.1	2.8	0.8	1.7	1.9	2.0	1.8	2.0	2.0
Depression (self-reported)	2.2	2.6	4.9	2.0	-0.1	1.9	2.2	1.8	1.1	1.1	1.6	1.8	-0.4	1.9	2.0	1.7	1.8	1.1	1.2	-0.8	1.6	1.7	1.0	1.8	2.0	1.8	1.9	1.8	1.7
Worry too long after embarrassment	2.2	3.7	6.4	2.1	1.3	1.8	1.9	2.1	2.0	0.9	2.0	2.0	-0.2	2.2	2.2	2.1	2.0	2.4	1.9	0.9	1.8	1.5	2.5	1.9	2.1	2.1	1.9	2.0	2.1
Pulse wave peak to peak time	2.2	2.5	4.5	-1.7	-1.3	-1.6	-1.3	-1.5	-1.4	-1.6	-1.0	-1.5	0.9	-0.5	-1.7	-1.4	-1.4	-2.0	-1.6	2.0	-1.9	-2.1	-2.0	-1.3	-1.9	-1.6	-1.6	-1.8	-1.8
Smoking status: Current	2.2	3.4	5.8	1.9	2.3	1.8	1.3	2.0	2.4	1.8	2.1	2.1	0.7	1.3	1.7	1.9	2.1	1.8	2.4	0.0	2.0	1.7	1.8	2.0	1.7	1.9	2.0	1.8	1.9
Deep venous thrombosis (DVT) (self-reported)	2.2	2.8	4.6	1.8	1.4	1.7	2.1	1.8	1.3	1.4	1.9	1.8	0.8	2.1	1.7	1.8	1.8	1.9	1.2	0.9	1.6	0.8	1.7	1.9	1.9	1.9	1.6	1.8	1.7
Impedance of leg (right)	2.1	10.3	38.7	-3.3	-2.3	-2.8	-2.5	-2.7	-2.6	-3.4	-1.5	-2.7	3.1	0.9	-2.8	-2.5	-2.6	-3.0	-1.9	6.1	-4.3	-6.2	-2.9	-2.0	-3.5	-3.0	-2.8	-3.6	-3.3
Diabetes (self-reported)	2.1	3.3	7.0	2.1	1.4	1.9	2.6	1.9	0.9	2.0	2.0	1.9	0.9	2.3	2.0	1.8	1.9	2.1	1.3	1.5	1.3	0.9	1.1	2.0	2.2	1.9	1.8	1.9	2.0
Arm fat mass (left)	2.1	8.8	13.9	3.6	3.3	3.3	3.7	3.0	2.1	3.5	2.6	3.2	1.4	2.1	3.0	3.0	2.9	3.1	1.9	-0.6	3.7	3.0	1.4	3.1	3.7	3.1	3.1	3.4	3.4
BMI	2.0	11.8	21.7	4.0	4.1	3.6	3.5	3.6	3.0	3.9	2.9	3.7	1.0	1.6	3.5	3.2	3.5	3.4	2.7	-2.3	4.3	4.7	2.1	3.3	4.0	3.5	3.5	3.9	3.9
Pain all over the body in last month	2.0	2.2	6.3	1.3	1.3	1.4	1.2	1.6	1.5	-0.6	1.6	1.5	2.5	1.5	1.4	1.2	1.6	1.6	2.2	1.3	0.8	1.3	1.0	1.7	1.5	1.3	1.5	1.4	1.6
Noisy workplace	2.0	2.5	3.6	1.7	1.7	1.6	1.5	1.6	1.7	1.3	1.7	1.6	1.7	1.2	1.8	1.7	1.5	1.9	1.8	0.6	1.2	0.9	1.0	1.8	1.7	1.6	1.8	1.6	1.8
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.5	4.9	-1.5	-2.2	-1.5	-1.6	-1.8	-1.8	-0.6	-1.9	-1.8	-1.3	-2.2	-1.7	-1.7	-1.8	-1.9	-1.4	-0.6	-1.4	-0.7	-1.4	-1.7	-1.3	-1.7	-1.6	-1.5	-1.4
Lung cancer (father)	2.0	2.3	6.4	1.4	2.5	1.6	1.3	1.6	1.5	0.2	1.8	1.6	1.1	1.5	1.7	1.2	1.6	1.8	1.7	0.6	1.1	1.2	1.8	1.7	1.6	1.4	1.6	1.5	1.6
Exposure to tobacco smoke at home	2.0	2.3	5.4	1.2	1.8	1.5	1.1	1.6	1.7	0.1	1.8	1.5	2.2	1.7	1.6	1.3	1.6	1.3	2.3	2.0	1.2	0.2	0.9	1.7	1.2	1.4	1.5	1.2	1.3
Leg fat percentage (left)	2.0	7.4	12.7	3.1	3.6	3.0	3.1	2.8	2.3	2.5	2.7	3.0	2.3	2.6	2.8	2.8	2.8	2.5	2.1	0.6	3.3	2.2	1.0	3.0	3.0	2.8	3.0	2.9	2.9
Ulcerative Colitis (UC)	1.9	3.5	5.7	2.0	1.6	1.8	1.7	2.0	2.1	1.2	2.0	1.9	1.3	1.5	2.2	2.1	1.9	1.9	1.2	-0.1	1.5	2.4	1.8	2.0	2.2	2.0	1.9	2.2	2.4
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	6.4	1.5	1.6	1.4	0.9	1.5	1.8	1.1	1.2	1.5	0.5	0.3	0.9	1.0	1.4	1.7	1.8	-0.5	1.3	2.5	1.6	1.3	1.4	1.4	1.6	1.6	1.5
Medication: Atenolol	1.9	2.4	5.8	-1.4	-2.4	-1.5	-1.4	-1.7	-1.8	0.8	-1.7	-1.6	-1.1	-1.0	-1.8	-1.5	-1.7	-1.7	-1.5	0.1	-1.1	-1.9	-1.3	-1.7	-1.5	-1.6	-1.7	-1.6	-1.7
Body fat percentage	1.9	7.4	13.5	3.3	3.3	3.0	3.7	2.9	1.8	2.6	2.6	3.0	2.5	2.7	2.9	2.8	2.7	2.7	1.6	0.7	3.0	1.8	0.8	3.0	3.3	2.8	2.9	2.9	3.0
Average weekly beer plus cider intake	1.9	2.7	5.2	1.9	0.5	1.8	1.7	1.9	1.5	1.5	1.7	1.9	0.1	2.3	1.8	1.5	1.9	1.4	1.7	1.0	2.0	1.1	1.3	1.7	1.8	1.7	1.8	1.8	1.8
Illnesses of siblings	1.8	2.5	5.4	-1.7	-1.5	-1.7	-1.8	-1.6	-1.5	0.4	-1.4	-1.6	-1.3	-1.4	-1.4	-2.1	-1.5	-1.8	-1.2	-0.1	-1.6	-2.3	-0.5	-1.7	-1.9	-1.8	-1.6	-1.8	-1.9
Falls in the last year	1.8	2.5	5.0	1.9	0.7	1.5	1.9	1.6	1.1	2.2	1.3	1.7	-0.8	1.0	1.2	1.5	1.6	1.8	1.0	-1.4	1.7	2.2	1.7	1.4	1.9	1.7	1.3	1.8	1.7
Pulse rate	1.8	3.1	4.7	2.0	1.2	1.8	1.8	1.8	1.5	1.7	1.6	1.8	-0.1	0.5	2.0	1.7	1.8	1.9	1.7	-1.8	2.2	2.2	1.6	1.7	2.1	1.8	1.8	2.0	2.1
Qualifications: College or University degree	1.8	5.7	30.3	-2.2	-3.0	-2.4	-2.2	-2.2	-1.7	-0.3	-2.9	-2.2	-3.4	-2.9	-2.3	-1.8	-2.2	-2.3	-1.7	-5.5	-1.5	0.1	-0.9	-2.7	-1.9	-1.9	-2.4	-1.7	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.1	3.3	-1.6	-1.7	-1.5	-1.8	-1.6	-1.3	-0.9	-1.7	-1.6	-1.4	-1.5	-1.6	-1.6	-1.6	-1.8	-0.9	-0.4	-1.5	-1.4	-0.9	-1.6	-1.5	-1.6	-1.4	-1.4	-1.4
Pulse rate, automated reading	1.8	5.9	9.2	2.6	2.3	2.8	3.0	2.5	1.9	1.4	2.5	2.5	1.6	2.0	2.9	2.6	2.6	2.7	2.0	0.7	2.6	1.7	1.8	2.7	3.0	2.7	2.6	2.8	2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.8	8.1	-2.1	-2.1	-2.3	-2.8	-1.9	-0.8	-1.0	-2.2	-1.9	-1.5	-2.8	-2.1	-2.1	-1.8	-1.9	-1.6	-2.5	-1.7	0.4	-1.0	-2.3	-2.1	-1.9	-2.1	-1.8	-1.8
Hearing difficulty/problems with background noise	1.7	2.7	9.2	1.6	-0.9	1.3	1.1	1.4	1.3	3.0	0.9	1.5	-2.3	1.2	1.8	0.9	1.4	1.1	1.5	-2.4	1.7	2.4	2.1	1.1	1.7	1.4	1.4	1.7	1.6
Mood swings	1.7	3.0	4.9	2.0	1.6	1.8	1.8	1.8	1.5	1.0	1.8	1.9	1.2	2.2	1.7	1.6	1.7	1.9	2.0	0.8	1.8	2.0	1.1	1.8	1.9	1.7	1.9	1.8	2.0
Hearing aid user	1.7	2.0	3.4	1.5	0.6	1.5	1.4	1.5	1.6	0.3	1.5	1.5	1.7	1.5	1.8	1.6	1.4	1.2	1.5	-0.0	0.6	1.5	0.5	1.7	1.5	1.6	1.7	1.5	1.5
Financial situation satisfaction	1.7	2.1	3.9	1.5	0.9	1.5	1.7	1.7	1.5	0.7	1.7	1.7	1.1	2.0	1.7	1.3	1.7	1.4	1.5	1.0	1.3	0.9	1.1	1.7	1.5	1.5	1.6	1.5	1.4
Chest pain or discomfort	1.6	2.3	7.2	1.7	0.5	1.4	1.5	1.6	1.6	0.9	1.2	1.6	-0.4	1.3	1.3	1.7	1.6	1.7	1.4	-0.7	1.5	2.7	0.9	1.3	1.8	1.8	1.4	1.9	1.8
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	4.8	-1.6	-1.8	-1.5	-1.4	-1.6	-1.4	-2.2	-1.5	-1.6	1.1	-0.7	-1.3	-1.4	-1.6	-1.7	-0.9	2.0	-2.0	-2.0	-2.1	-1.4	-1.5	-1.6	-1.4	-1.6	-1.5
Ever taken oral contraceptive pill	1.6	1.8	5.9	-1.4	-2.4	-1.6	-1.9	-1.2	-0.8	-1.0	-1.3	-1.2	-0.7	-1.0	-1.6	-1.8	-1.1	-1.6	-0.3	0.3	-1.2	-0.4	-1.0	-1.5	-1.5	-1.5	-1.4	-1.3	-1.3
Myopia	1.6	2.4	5.0	-1.6	-1.5	-1.6	-1.7	-1.6	-1.4	-0.3	-1.8	-1.7	-2.2	-2.0	-1.5	-1.6	-1.7	-1.5	-2.0	-0.9	-1.1	-0.5	-0.7	-1.8	-1.5	-1.6	-1.7	-1.4	-1.5
Hearing difficulty/problems: Yes	1.5	2.3	8.3	1.6	-0.1	1.3	1.0	1.3	1.3	2.6	0.8	1.4	-1.2	0.9	1.8	1.0	1.2	1.2	1.3	-2.9	1.4	2.5	1.3	1.0	1.6	1.4	1.3	1.6	1.5
Pack years adult smoking proportion	1.5	2.3	6.2	1.5	1.3	1.6	0.8	1.6	2.2	1.1	1.6	1.7	1.0	1.3	1.2	1.5	1.5	1.5	2.5	1.2	1.8	0.9	1.5	1.6	1.4	1.6	1.6	1.6	1.6
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	4.2	-1.2	-2.0	-1.3	-1.3	-1.5	-1.4	-0.9	-1.5	-1.5	-1.4	-1.3	-1.2	-1.3	-1.4	-1.5	-1.2	-1.0	-1.3	-0.6	-1.1	-1.4	-1.1	-1.4	-1.4	-1.2	-1.2
Medication: Omeprazole	1.5	1.7	3.8	1.3	1.3	1.3	1.0	1.2	1.3	1.9	0.8	1.2	-0.4	0.1	1.3	1.4	1.1	1.0	1.5	-1.2	1.6	1.7	1.4	1.2	1.4	1.4	1.5	1.6	1.5
Leg fat mass (right)	1.5	6.0	12.3	2.9	3.5	2.7	3.0	2.5	1.8	3.0	2.3	2.6	2.1	2.0	2.4	2.4	2.4	2.3	1.8	0.2	2.9	1.9	0.6	2.6	2.8	2.4	2.6	2.6	2.6
Basal cell carcinoma (self-reported)	1.5	1.8	4.3	1.1	1.8	1.3	1.5	1.5	1.5	-0.3	1.5	1.4	2.1	1.3	1.5	1.6	1.4	1.4	0.7	0.4	1.3	0.9	0.9	1.5	1.3	1.5	1.3	1.4	1.4
Verbal and Numeric Reasoning (VNR)	1.4	3.5	5.5	-2.0	-0.7	-1.8	-1.4	-2.1	-2.3	-1.9	-2.1	-2.1	-0.1	-1.4	-2.0	-1.7	-2.1	-1.7	-2.1	1.2	-1.8	-1.7	-2.2	-2.0	-1.8	-2.0	-2.2	-2.1	-2.0
Lupus	1.4	2.2	4.3	-1.7	-2.1	-1.8	-1.7	-1.5	-1.2	-0.2	-1.6	-1.5	-0.9	-1.2	-1.7	-1.8	-1.5	-1.6	-1.5	-0.8	-1.2	-1.0	-1.2	-1.7	-1.6	-1.5	-1.7	-1.4	-1.6
Chronotype (morning person)	1.4	3.2	16.8	-1.5	-0.1	-1.0	-1.6	-1.2	-0.5	-4.1	-0.4	-1.3	3.1	-0.6	-1.3	-1.1	-1.1	-1.2	-0.0	3.4	-1.7	-2.5	-3.1	-0.7	-1.8	-1.3	-1.1	-1.8	-1.5
Pulse wave Arterial Stiffness index	1.4	1.6	3.4	1.4	0.9	1.2	1.0	1.1	1.0	1.6	0.7	1.2	-1.0	0.3	1.3	1.0	1.1	1.6	1.3	-1.9	1.5	1.6	1.6	0.9	1.5	1.2	1.2	1.5	1.4
Average weekly champagne plus white wine intake	1.4	1.9	4.6	-1.2	-1.7	-1.4	-1.6	-1.4	-0.8	-1.9	-1.5	-1.3	-0.3	-1.1	-1.3	-1.0	-1.4	-1.4	-0.6	-1.1	-2.0	-0.0	-2.1	-1.5	-1.4	-1.3	-1.2	-1.3	-1.4
Leg fat mass (left)	1.4	5.4	10.9	2.7	3.3	2.5	2.8	2.4	1.7	3.0	2.1	2.5	2.1	1.8	2.2	2.2	2.3	2.1	1.6	-0.1	3.0	2.0	0.5	2.5	2.7	2.3	2.5	2.5	2.5
Medication: Amlodipine	1.3	1.9	5.5	-1.2	-2.1	-1.5	-1.8	-1.3	-0.9	1.4	-1.5	-1.3	-2.4	-1.4	-1.6	-1.7	-1.3	-1.2	-0.8	0.4	-0.8	-0.5	-0.7	-1.5	-1.4	-1.4	-1.2	-1.2	-1.2
Angina (self-reported)	1.3	1.8	2.7	-1.4	-1.4	-1.4	-1.4	-1.5	-1.4	0.2	-1.6	-1.5	-1.0	-1.2	-1.6	-1.5	-1.6	-1.4	-1.3	0.0	-1.1	-0.9	-1.6	-1.5	-1.3	-1.4	-1.5	-1.3	-1.4
Migraine (self-reported)	1.3	1.6	4.0	1.6	0.8	1.3	2.0	1.2	0.3	1.0	1.0	1.2	-0.4	1.4	1.6	1.2	1.2	1.5	1.0	-0.1	0.8	0.9	1.5	1.3	1.9	1.3	1.3	1.6	1.6
Osteoporosis (self-reported)	1.3	1.7	3.4	1.4	1.2	1.4	0.9	1.2	1.6	1.2	1.3	1.3	0.0	0.7	1.0	1.4	1.2	1.4	1.4	-0.1	1.3	1.8	1.6	1.3	1.3	1.4	1.4	1.4	1.4
Unable to work because of sickness or disability	1.3	1.7	8.1	0.9	1.0	1.2	0.8	1.1	1.3	-0.8	1.5	1.1	2.5	1.2	1.0	1.0	1.1	1.4	1.7	2.8	0.8	-0.0	1.1	1.4	0.9	0.9	1.1	0.9	1.1
Pack years of smoking	1.3	1.9	5.2	1.4	1.2	1.4	0.6	1.4	2.1	1.1	1.5	1.5	0.8	1.2	1.1	1.3	1.4	1.3	2.3	1.0	1.7	0.8	1.4	1.4	1.2	1.4	1.5	1.4	1.4
Impedance of whole body	1.3	6.8	28.2	-2.5	-2.4	-2.2	-1.4	-2.1	-2.5	-3.2	-1.3	-2.1	2.5	1.0	-1.9	-1.9	-2.1	-2.1	-1.9	5.2	-3.4	-5.3	-2.3	-1.5	-2.4	-2.2	-2.2	-2.7	-2.5
Alzheimer’s Disease (in mother)	1.2	1.4	4.4	-1.3	-2.1	-1.2	-1.5	-1.2	-0.9	-0.6	-1.2	-1.3	-0.4	-1.4	-1.1	-1.3	-1.3	-1.4	-0.3	0.1	-1.4	-1.0	-1.0	-1.3	-1.2	-1.3	-1.3	-1.2	-1.0
Angina	1.2	1.5	2.4	-1.2	-1.4	-1.3	-1.2	-1.4	-1.3	0.3	-1.4	-1.3	-1.1	-1.0	-1.5	-1.4	-1.5	-1.3	-1.2	-0.1	-1.0	-0.8	-1.6	-1.4	-1.2	-1.3	-1.4	-1.2	-1.3
Waist circumference	1.2	4.3	14.3	2.6	1.9	2.3	2.6	2.0	1.2	3.8	1.6	2.2	0.6	1.6	1.7	1.8	2.0	2.0	1.4	-0.4	2.9	2.3	0.7	2.0	2.5	2.0	2.0	2.3	2.3
Qualifications: None of the above	1.2	2.5	10.0	1.4	1.7	1.5	1.4	1.6	1.3	0.6	2.0	1.5	2.1	2.1	1.4	1.2	1.4	1.7	1.5	3.2	1.1	0.0	1.4	1.8	1.2	1.4	1.5	1.2	1.5
Tense / ‘highly strung’	1.2	2.0	7.1	-1.1	-2.7	-1.2	-1.2	-1.3	-1.4	-0.6	-1.6	-1.2	-2.1	-1.2	-1.1	-1.6	-1.3	-1.7	-0.9	-2.3	-0.8	0.1	-1.3	-1.5	-1.1	-1.3	-1.2	-1.1	-1.3
Medication: Ventolin 100micrograms inhaler	1.2	1.6	2.5	1.3	0.8	1.3	1.2	1.4	1.6	-0.2	1.4	1.4	1.1	1.0	1.4	1.5	1.4	1.2	1.0	0.8	0.8	1.3	1.2	1.5	1.3	1.4	1.4	1.4	1.5
Number of full brothers	1.2	1.5	5.2	-1.1	-2.3	-1.3	-1.5	-1.0	-0.7	-0.7	-1.4	-1.1	-1.4	-1.3	-1.3	-1.3	-1.1	-1.4	-0.5	-1.0	-1.3	0.2	-1.3	-1.4	-1.2	-1.1	-1.2	-1.0	-1.2
Alcohol intake frequency.	1.2	2.9	5.9	1.9	2.4	1.8	2.0	1.7	1.3	2.4	1.8	1.8	1.3	1.2	1.8	1.5	1.8	2.2	0.8	0.9	1.6	0.7	1.1	1.8	1.8	1.7	1.7	1.7	1.7
Medication for cholesterol	1.2	1.8	3.6	-1.4	-1.4	-1.8	-1.5	-1.3	-0.9	-1.2	-1.3	-1.4	0.2	-1.4	-1.3	-1.5	-1.3	-1.4	-0.5	-1.2	-1.9	-1.1	-1.4	-1.5	-1.4	-1.3	-1.5	-1.4	-1.4
Tinnitus: Yes, now most or all of the time	1.2	1.4	2.5	1.3	0.9	1.3	0.8	1.1	1.4	1.6	1.2	1.2	0.8	0.8	1.4	1.3	1.2	1.2	1.4	-0.0	1.5	0.9	1.3	1.2	1.2	1.2	1.2	1.3	1.4
Medication: Bendroflumethiazide	1.2	1.8	4.2	1.5	2.0	1.6	1.5	1.1	0.8	1.8	1.0	1.2	-0.5	1.0	1.3	1.3	1.1	1.5	0.8	0.2	2.1	0.9	1.6	1.3	1.4	1.3	1.5	1.4	1.3
Medication: Lisinopril	1.2	1.6	3.4	-1.2	-1.8	-1.4	-1.7	-1.3	-0.9	0.2	-1.0	-1.2	-1.3	-0.8	-1.3	-1.3	-1.2	-1.8	-1.3	0.5	-0.8	-1.5	-0.8	-1.2	-1.6	-1.3	-1.2	-1.4	-1.4
Type 2 Diabetes (T2D) (2018)	1.1	2.0	7.7	1.7	0.9	1.4	1.9	1.5	0.8	2.8	1.3	1.6	-0.4	1.3	1.3	1.4	1.5	1.5	0.8	0.7	1.5	1.0	0.8	1.4	1.7	1.5	1.4	1.6	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	5.4	1.4	0.1	1.0	1.2	1.1	0.7	1.5	0.6	1.1	-0.9	1.1	1.2	0.7	1.2	0.9	1.0	-2.3	0.8	2.3	0.2	0.8	1.5	1.1	1.1	1.4	1.2
Mean time to correctly identify matches	1.1	2.2	7.7	1.2	0.9	1.2	1.1	1.4	1.6	-0.2	2.0	1.3	1.8	2.0	1.6	1.3	1.4	1.8	1.1	2.8	0.8	-0.8	2.2	1.6	1.0	1.3	1.3	1.0	1.2
Whole body fat mass	1.1	4.6	9.4	2.6	2.8	2.3	3.0	2.1	1.1	3.1	1.9	2.3	2.1	1.9	2.0	2.0	2.0	2.1	1.2	0.3	2.6	1.4	0.2	2.3	2.6	2.1	2.1	2.3	2.3
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	3.3	-1.2	-0.5	-1.1	-1.5	-1.4	-1.0	0.5	-1.3	-1.4	-1.8	-1.4	-1.0	-0.9	-1.3	-1.1	-0.5	-0.2	-0.9	-1.2	-0.2	-1.3	-1.3	-1.2	-1.2	-1.3	-1.2
Triglycerides	1.0	1.6	3.1	1.2	1.7	1.3	1.8	1.4	0.8	1.0	1.6	1.3	1.5	1.6	1.2	1.2	1.3	1.4	0.7	1.4	0.8	0.3	0.6	1.6	1.4	1.1	1.4	1.1	1.2
Trunk fat percentage	1.0	4.1	9.5	2.5	2.4	2.2	3.1	2.0	0.8	2.3	1.9	2.1	2.4	2.3	2.1	2.0	1.9	1.9	0.8	1.1	2.2	0.8	0.0	2.2	2.5	2.0	2.0	2.1	2.2
Age when periods started (menarche)	1.0	2.3	4.9	1.7	1.3	1.7	2.2	1.7	1.0	0.0	1.6	1.7	0.9	1.8	1.7	1.9	1.8	1.5	1.3	-0.1	1.1	1.2	0.8	1.8	1.9	1.7	1.6	1.7	1.6
Medication: Ibuprofen	1.0	1.2	2.7	-1.0	-1.2	-0.8	-0.8	-1.3	-1.6	-0.7	-1.4	-1.3	-0.8	-1.6	-1.1	-1.1	-1.4	-1.3	-1.0	-0.2	-0.8	-0.6	-1.0	-1.1	-0.8	-1.2	-1.1	-1.0	-0.9
Wears glasses or contact lenses	1.0	1.2	2.2	1.3	1.5	1.3	1.4	1.2	0.8	-0.2	0.9	1.1	0.1	0.7	1.5	1.1	1.1	1.2	0.6	-0.1	1.4	1.2	0.6	1.2	1.3	1.2	1.2	1.3	1.1
Risk taking	1.0	1.5	8.6	-0.7	-0.9	-0.7	-0.5	-1.1	-1.4	2.3	-1.3	-0.9	-2.4	-1.0	-1.4	-0.7	-1.0	-1.1	-1.3	-2.9	-0.2	0.3	-0.4	-1.0	-0.5	-0.9	-0.7	-0.7	-0.8
Alcohol drinker status: Previous	1.0	1.1	7.1	-0.4	-1.1	-0.8	-0.4	-0.7	-1.1	1.6	-1.0	-0.6	-2.7	-1.2	-0.4	-1.0	-0.6	-0.6	-1.2	-2.2	-0.6	-0.3	0.3	-0.9	-0.5	-0.7	-0.8	-0.5	-0.7
Worry (Nagel 2018)	0.9	1.9	5.5	-1.1	-2.4	-1.4	-1.3	-1.3	-1.4	-1.9	-1.5	-1.3	-0.9	-0.9	-1.0	-1.7	-1.3	-1.4	-1.1	-1.8	-1.4	-0.2	-1.3	-1.5	-1.2	-1.4	-1.3	-1.3	-1.3
Ovarian Cancer	0.9	1.2	2.7	1.0	-0.0	0.7	0.6	1.1	1.5	1.6	0.9	1.1	-0.6	0.5	0.9	1.1	1.1	1.1	1.2	-0.8	1.3	1.6	1.4	0.8	1.0	1.2	0.9	1.2	1.1
Cardiovascular Disease	0.9	2.8	15.2	1.9	0.1	1.7	2.0	1.3	0.5	3.9	1.1	1.4	-2.2	1.2	1.6	1.4	1.4	1.4	0.3	0.4	2.2	1.3	1.9	1.4	2.1	1.5	1.6	1.8	1.8
Ever used hormone-replacement therapy (HRT)	0.9	1.1	1.8	1.1	0.8	1.3	0.9	1.2	1.3	0.7	1.2	1.2	0.7	0.7	1.1	1.1	1.2	1.1	0.8	0.2	1.3	1.2	1.0	1.2	1.0	1.2	1.2	1.1	1.1
Qualifications: CSEs or equivalent	0.9	1.2	4.4	-1.0	0.1	-0.9	-0.7	-0.9	-1.0	-1.7	-0.5	-0.9	1.6	-0.8	-1.0	-0.9	-0.8	-0.6	-0.6	2.1	-1.4	-1.3	-1.9	-0.6	-1.0	-1.0	-0.7	-1.2	-1.0
Hayfever, allergic rhinitis or eczema	0.9	2.1	9.6	1.3	-1.4	1.3	0.9	1.4	1.6	0.9	1.0	1.4	-1.3	0.4	1.1	1.2	1.4	1.3	1.1	-2.2	2.0	3.1	0.6	1.1	1.4	1.4	1.4	1.6	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.4	-1.1	-1.3	-1.2	-1.2	-1.1	-0.7	-0.6	-1.3	-1.1	-1.0	-1.4	-0.8	-0.9	-1.0	-1.4	-1.0	-1.6	-1.2	0.1	-0.8	-1.1	-0.8	-0.9	-1.0	-0.7	-0.8
Medication: Blood pressure	0.9	1.6	4.9	-1.1	-2.2	-1.4	-1.0	-1.3	-1.5	0.6	-1.4	-1.3	-1.6	-0.7	-1.0	-1.4	-1.3	-1.2	-1.6	0.6	-1.1	-1.7	-0.8	-1.4	-1.0	-1.2	-1.3	-1.1	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	4.5	0.9	0.6	0.9	0.7	0.7	0.7	2.1	0.2	0.8	-1.3	-0.3	0.9	0.9	0.7	0.5	1.0	-1.8	1.4	1.7	1.0	0.6	1.0	0.9	1.0	1.2	1.1
Pain experienced in last month	0.9	1.5	3.7	-1.4	-1.0	-1.3	-1.4	-1.3	-0.6	-0.4	-1.2	-1.3	-1.8	-1.3	-1.3	-0.8	-1.3	-1.0	-1.9	-1.0	-1.0	-1.1	-0.0	-1.4	-1.4	-1.0	-1.4	-1.2	-1.3
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.2	1.0	1.2	0.8	1.0	1.5	0.7	0.4	1.0	1.0	1.0	1.0	0.8	0.8	0.9	0.8	0.8	1.5	1.2	0.5	0.4	1.0	0.8	0.8	1.0	0.8	0.8
Heel T-Score	0.8	6.1	13.7	-2.4	-3.4	-2.3	-0.5	-2.2	-3.7	-2.3	-1.8	-2.4	0.8	0.5	-2.5	-1.9	-2.4	-2.7	-2.8	2.0	-3.4	-3.6	-3.5	-1.7	-1.9	-2.3	-2.4	-2.5	-2.4
Relative age of first facial hair	0.8	1.7	4.6	1.4	2.2	1.3	1.4	1.2	1.1	0.2	1.1	1.2	0.1	0.3	1.6	1.5	1.2	1.8	0.6	-1.5	0.9	1.7	1.5	1.3	1.6	1.3	1.2	1.4	1.4
Ever had hysterectomy (womb removed)	0.8	1.0	3.5	1.0	1.9	0.8	0.4	0.9	1.4	1.6	1.1	0.9	0.7	-0.1	0.9	0.9	1.0	1.2	0.9	-0.6	1.1	0.9	0.9	0.9	0.7	0.9	0.8	0.8	0.9
Sitting height	0.8	6.0	10.5	-2.7	-1.1	-2.7	-2.2	-2.7	-2.9	0.4	-2.5	-2.6	-0.1	-1.9	-3.2	-2.7	-2.7	-2.3	-1.8	1.7	-2.3	-3.2	-2.7	-2.5	-2.7	-2.8	-2.7	-2.9	-2.8
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	5.8	-1.3	-2.4	-1.3	-0.3	-1.3	-2.2	-1.6	-1.2	-1.4	-0.1	-0.4	-1.5	-1.1	-1.4	-1.4	-1.2	0.4	-1.9	-1.3	-2.0	-1.1	-1.0	-1.3	-1.4	-1.4	-1.2
Number of live births	0.8	1.2	3.5	1.0	-0.4	0.8	0.2	1.0	1.4	1.5	0.8	1.1	-0.6	0.1	1.0	0.5	1.0	0.9	1.6	-1.9	1.5	1.7	1.7	0.7	0.7	0.8	0.9	0.9	0.9
Gout (self-reported)	0.8	1.1	9.9	-0.7	-1.1	-0.3	-0.1	-0.5	-1.0	-1.1	-0.3	-0.6	1.5	0.9	-0.8	-0.6	-0.5	-0.8	-0.7	3.1	-0.6	-1.6	-1.9	-0.3	-0.7	-0.7	-0.5	-0.8	-0.7
Age at first live birth	0.8	1.5	2.4	-1.4	-1.4	-1.2	-1.4	-1.3	-0.8	-1.3	-1.3	-1.3	0.5	-1.1	-1.4	-0.9	-1.3	-1.4	-0.7	0.2	-1.6	-1.1	-1.3	-1.3	-1.4	-1.2	-1.2	-1.3	-1.2
Family relationship satisfaction	0.8	1.0	3.6	1.1	0.2	1.1	1.3	1.1	0.6	0.8	1.1	1.0	0.9	1.9	1.2	0.9	1.1	0.9	0.4	1.1	0.8	-0.1	0.8	1.2	1.2	1.0	1.0	1.1	1.1
Supplements: Vitamin C	0.8	0.9	1.5	-1.0	-1.1	-1.1	-1.0	-1.0	-0.8	-0.1	-1.0	-1.0	-0.3	-1.2	-1.0	-0.9	-0.9	-1.0	-1.1	-0.5	-1.2	-0.5	-1.1	-0.9	-1.0	-1.0	-1.0	-1.0	-0.9
Age started oral contraceptive pill	0.8	1.0	3.3	1.0	1.2	1.0	0.7	0.9	0.8	1.4	0.8	0.9	-0.5	0.9	1.0	0.7	1.0	1.0	1.2	-1.2	1.8	0.4	1.5	0.7	0.8	0.8	0.8	0.9	0.8
Fasting Glucose	0.7	0.9	2.8	-1.1	-0.2	-0.4	-1.1	-0.7	-0.9	0.1	-1.5	-1.1	-0.3	-1.1	-1.4	-0.6	-1.7	-1.1	-1.2	0.2	-0.6	-0.6	-0.9	-0.9	-0.9	-0.7	-0.7	-0.7	-0.9
Allergy or Eczema	0.7	1.7	10.2	0.7	-3.0	0.6	0.3	0.5	0.6	1.2	-0.1	0.5	-3.2	-0.1	0.2	0.4	0.5	0.5	0.3	-2.7	1.5	2.9	0.5	0.2	0.8	0.6	0.6	1.0	0.7
Trunk fat mass	0.7	3.2	8.1	2.2	2.3	1.9	2.6	1.7	0.6	2.9	1.5	1.9	2.2	1.7	1.6	1.6	1.6	1.6	0.7	0.7	2.1	0.8	-0.4	1.9	2.2	1.6	1.7	1.8	1.8
Happiness	0.7	0.9	2.3	1.0	0.1	0.7	1.1	0.8	0.5	1.5	0.5	0.9	-0.5	1.0	0.7	0.8	0.8	1.1	0.0	-1.1	1.3	1.5	0.5	0.7	1.2	1.0	0.7	1.2	1.0
Impedance of arm (left)	0.7	3.1	12.3	-1.6	-2.4	-1.4	-0.7	-1.4	-1.8	-2.4	-1.0	-1.5	1.3	0.8	-1.2	-1.1	-1.4	-1.2	-1.7	3.4	-2.4	-3.5	-1.6	-1.1	-1.5	-1.4	-1.6	-1.7	-1.6
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.0	-0.9	-0.5	-0.9	-1.2	-0.8	-0.5	-1.0	-0.8	-0.8	0.3	-0.8	-0.9	-1.0	-0.8	-0.6	-0.8	1.3	-1.4	-0.6	-1.4	-0.9	-1.1	-0.9	-0.8	-0.9	-0.9
Illnesses of father: High blood pressure	0.7	0.8	3.0	-1.0	-1.3	-1.0	-1.2	-0.9	-0.6	-0.5	-1.0	-1.0	-0.0	-1.3	-0.8	-0.8	-1.0	-0.8	-1.7	-0.0	-0.8	-0.5	-0.8	-1.0	-0.8	-0.9	-1.0	-0.7	-0.6
Depressed Affect (Nagel 2018)	0.6	1.3	3.4	1.2	0.8	1.0	1.1	1.1	0.8	0.9	1.2	1.2	1.0	1.9	0.9	0.8	1.1	1.3	1.2	1.3	1.1	1.6	0.7	1.1	1.2	1.0	1.0	1.1	1.2
Reaction Time	0.6	1.2	8.4	0.7	0.3	0.6	0.5	0.9	1.2	-1.1	1.4	0.8	1.4	1.4	0.9	0.9	0.8	1.4	0.4	2.9	0.1	-0.5	1.6	1.0	0.6	0.9	0.7	0.7	0.8
Smoking Status	0.6	1.3	11.2	0.9	0.6	0.7	0.5	0.8	0.7	3.3	0.4	0.9	-2.4	0.1	0.5	0.7	0.7	0.3	0.7	-1.5	1.4	1.4	1.1	0.4	0.9	0.9	0.7	0.9	0.8
Diabetes (father)	0.6	0.7	1.7	-0.7	-1.2	-0.9	-0.5	-0.9	-1.1	0.4	-0.9	-0.8	-1.0	-1.1	-0.9	-0.9	-0.9	-0.5	-1.3	0.2	-0.4	-0.6	-0.7	-0.9	-0.7	-0.8	-0.9	-0.8	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.4	0.9	0.2	0.9	0.7	0.9	0.8	-0.3	1.0	0.9	0.9	1.8	0.9	0.8	0.9	0.7	1.0	1.4	0.6	0.8	0.8	1.0	1.0	0.8	0.9	0.9	1.0
Headache pain in last month	0.6	1.0	2.1	1.4	-0.2	1.1	1.2	0.8	0.4	1.2	0.8	1.0	-0.5	0.6	0.9	1.1	1.0	1.3	1.0	0.5	1.0	1.1	1.0	0.9	1.5	1.0	1.0	1.2	1.4
Mouth/teeth dental problems: Loose teeth	0.6	0.7	5.9	-0.6	-1.0	-0.8	-0.6	-0.7	-0.7	0.4	-0.9	-0.6	-2.4	-0.7	-1.0	-0.7	-0.6	-0.6	-0.9	-1.1	-0.6	0.5	-0.0	-0.9	-0.5	-0.7	-0.7	-0.5	-0.6
Age at last live birth	0.6	0.9	2.3	-0.9	-1.4	-0.8	-1.5	-0.9	-0.2	0.0	-1.0	-0.9	-0.9	-1.5	-0.9	-0.9	-0.9	-1.0	0.3	-1.4	-0.5	-0.3	0.0	-1.1	-1.1	-0.9	-0.8	-0.8	-0.9
Leg pain on walking	0.6	0.7	1.9	0.9	0.7	0.9	0.5	0.6	1.0	0.9	0.6	0.7	-0.1	0.1	0.6	1.3	0.6	1.1	0.9	-0.7	0.6	1.4	1.1	0.8	1.0	0.9	0.9	1.0	1.1
Ever had bowel cancer screening	0.6	0.7	2.3	0.9	0.9	1.0	1.0	0.8	0.5	0.9	0.6	0.8	0.6	0.3	0.9	0.9	0.7	0.7	0.4	-0.7	0.8	1.5	0.3	0.9	1.0	0.8	0.9	0.9	0.9
Breast cancer (self-reported)	0.6	0.7	2.1	0.7	1.2	0.9	0.8	0.8	0.7	-0.3	1.0	0.8	1.4	1.2	0.7	0.7	0.8	0.7	0.6	1.1	1.1	0.2	0.5	1.0	0.7	0.7	0.8	0.7	0.8
Guilty feelings	0.6	0.9	4.2	-0.8	-2.1	-1.0	-0.8	-1.0	-1.2	-0.0	-0.9	-1.0	-0.7	-0.3	-0.5	-1.0	-1.0	-1.1	-1.2	0.1	-1.2	-1.1	-0.7	-0.9	-0.8	-1.0	-0.9	-0.9	-0.8
Medication: Blood pressure	0.6	1.2	3.8	1.2	0.5	1.3	1.3	0.8	0.2	1.9	0.8	0.9	-1.1	1.4	0.8	1.1	0.8	1.2	-0.3	1.3	1.7	0.4	1.3	1.0	1.1	0.9	1.0	1.0	1.0
Alcohol drinker status: Never	0.6	0.8	2.7	1.0	1.1	0.9	0.9	0.9	0.7	-0.3	1.0	0.8	1.6	0.8	1.2	0.8	0.9	1.1	0.5	0.4	0.1	0.1	0.5	0.9	1.0	0.8	0.9	0.8	1.0
Schizophrenia vs Biploar Disorder	0.5	0.7	7.9	-0.4	0.7	-0.4	-0.3	-0.3	-0.5	-0.7	0.1	-0.3	1.7	0.3	-0.4	-0.4	-0.2	-0.3	0.1	2.8	-0.8	-1.2	-0.8	-0.1	-0.5	-0.5	-0.4	-0.7	-0.4
Crohns Disease (2012)	0.5	0.8	2.1	-0.8	-0.7	-1.0	-0.9	-1.1	-1.3	0.6	-1.1	-1.0	-1.4	-0.8	-0.8	-1.2	-1.0	-0.8	-1.1	-0.8	-0.3	-0.4	-0.2	-1.1	-0.7	-1.1	-1.1	-0.8	-0.8
HbA1C	0.5	0.6	1.6	-0.5	-0.6	-1.3	-0.2	-1.0	-1.2	0.2	-0.4	-0.6	-0.1	-0.4	-0.2	-1.0	-0.2	-0.3	-0.3	0.2	-1.0	-0.9	-0.9	-0.9	-0.8	-1.1	-1.2	-1.0	-0.8
Townsend deprivation index at recruitment	0.5	0.7	1.9	1.0	0.0	0.8	1.0	0.9	0.6	1.4	0.7	1.0	-0.4	0.8	0.5	0.7	0.8	0.9	1.1	-0.2	0.8	1.0	0.8	0.8	1.0	0.9	0.8	1.0	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	4.3	-1.0	-2.1	-0.9	-0.1	-1.0	-1.8	-1.3	-0.9	-1.1	0.1	-0.2	-1.2	-0.7	-1.1	-1.0	-0.9	1.0	-1.4	-1.1	-1.8	-0.7	-0.7	-1.0	-1.0	-1.0	-0.9
Past tobacco smoking	0.5	1.0	10.5	0.0	0.8	0.1	0.2	0.3	0.5	-2.7	0.6	0.2	3.2	0.7	0.2	0.3	0.4	0.7	-0.1	1.9	-0.5	-0.4	-0.8	0.6	-0.0	0.2	0.2	-0.0	0.1
Comparative body size at age 10	0.5	1.3	12.0	0.5	2.4	0.6	0.6	0.7	0.7	-1.5	1.1	0.6	3.5	0.6	1.0	0.6	0.8	0.3	1.2	1.9	0.3	-0.3	-0.3	1.0	0.5	0.5	0.8	0.4	0.6
Neck or shoulder pain in last month	0.5	0.7	3.9	-0.4	-0.0	-0.2	-0.1	-0.2	-0.7	-1.0	-0.3	-0.2	1.8	0.5	-0.3	-0.8	-0.2	-1.1	-0.3	2.0	0.1	-1.1	-1.5	-0.3	-0.6	-0.6	-0.4	-0.7	-0.7
Illnesses of siblings: Diabetes	0.5	0.7	2.3	0.8	0.6	0.8	0.3	0.9	1.4	-0.2	0.9	0.9	0.7	0.4	0.8	0.9	0.9	0.6	0.9	-0.6	0.9	1.5	0.2	0.7	0.5	0.9	0.9	0.8	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	7.1	-0.8	-0.3	-0.8	-0.2	-0.7	-1.0	-0.1	-0.3	-0.6	1.5	0.4	-1.0	-0.7	-0.7	-0.3	-0.0	2.7	-1.2	-2.5	-0.7	-0.4	-0.8	-0.8	-0.8	-0.9	-0.9
Medication: Gliclazide	0.5	0.6	9.4	0.2	0.0	0.0	0.7	-0.1	-0.9	3.1	-0.3	-0.1	-1.3	-0.5	0.1	-0.0	-0.3	0.2	-0.9	-1.3	0.1	-0.4	0.7	-0.1	0.4	-0.0	-0.2	0.1	0.0
Ever depressed for a whole week	0.5	0.6	0.9	1.0	0.3	0.9	0.8	0.7	0.6	-0.4	0.7	0.8	0.5	0.8	0.8	0.9	0.6	0.7	0.9	-0.5	0.8	1.0	0.6	0.8	0.8	0.9	0.9	0.9	0.8
Depression (Nagel 2018)	0.4	0.6	1.5	-0.8	-1.2	-1.0	-0.9	-0.8	-0.9	-0.2	-0.9	-0.8	-0.6	-0.6	-0.9	-1.1	-0.9	-0.9	-0.5	0.1	-0.7	0.2	-0.5	-0.9	-0.7	-1.0	-1.0	-0.8	-0.7
Blood Eosinophil Count	0.4	3.2	44.6	-0.9	-6.7	-0.7	-0.6	-1.2	-2.1	0.5	-1.1	-1.1	-1.9	0.3	-1.2	-1.8	-1.2	-1.9	-0.6	1.0	-1.3	-1.0	-1.7	-1.0	-1.0	-1.4	-0.9	-1.2	-1.3
Waist Hip Ratio (WHR)	0.4	1.6	14.8	1.3	-1.4	0.9	1.1	0.3	-0.3	3.9	0.2	0.7	-3.0	0.9	-0.2	0.5	0.5	0.7	0.7	-1.1	1.5	1.2	1.1	0.5	1.2	0.6	0.7	0.9	0.8
Average weekly spirits intake	0.4	0.5	1.7	-0.7	-0.0	-0.7	-0.6	-0.8	-0.9	0.0	-0.8	-0.8	0.3	-1.3	-0.7	-0.8	-0.8	-1.0	-0.7	-0.2	-0.6	-0.8	-1.0	-0.6	-0.6	-0.9	-0.7	-0.7	-0.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.1	-0.5	-0.7	-0.7	-0.9	-0.6	-0.5	0.5	-0.7	-0.6	-0.9	-0.6	-0.9	-0.9	-0.6	-0.8	0.0	0.1	0.1	-0.1	-1.0	-0.9	-0.8	-0.7	-0.7	-0.7	-0.7
Diabetes (mother)	0.4	0.6	1.1	-0.6	-0.9	-0.7	-0.7	-0.8	-0.9	-0.1	-0.8	-0.7	-0.8	-0.9	-1.1	-0.9	-0.8	-0.5	-0.6	0.5	-0.5	-0.1	-0.8	-0.8	-0.8	-0.8	-0.7	-0.8	-0.8
Severe depression (siblings)	0.4	0.4	2.2	-0.2	-1.3	-0.2	-0.1	-0.5	-0.9	1.5	-0.6	-0.5	-1.2	-0.5	-0.5	-0.2	-0.6	-0.3	-0.8	-1.2	-0.5	-0.1	0.0	-0.4	-0.0	-0.4	-0.2	-0.2	-0.2
Hair/balding pattern: Pattern 2	0.4	0.6	2.3	0.7	1.5	0.9	0.7	0.7	0.6	0.8	0.9	0.7	0.6	0.3	0.6	0.8	0.7	0.8	0.8	-0.3	0.7	0.5	0.7	0.9	0.6	0.7	0.8	0.6	0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	0.9	0.8	0.2	0.6	0.6	0.8	0.7	-0.4	0.8	0.8	0.5	0.9	0.9	0.5	0.9	0.5	0.3	0.3	0.5	0.8	0.1	0.7	0.7	0.7	0.8	0.7	0.7
Weight	0.4	2.1	11.0	1.7	2.1	1.4	2.0	1.3	0.4	3.3	1.0	1.4	1.6	0.8	0.9	1.2	1.2	1.4	0.5	-0.0	1.9	1.1	-0.5	1.3	1.7	1.2	1.2	1.4	1.4
Impedance of arm (right)	0.4	1.8	8.6	-1.2	-2.2	-1.1	-0.6	-1.0	-1.0	-2.0	-0.6	-1.0	1.2	0.7	-0.8	-0.6	-1.0	-0.8	-1.2	2.9	-1.9	-2.8	-0.7	-0.7	-1.1	-0.9	-1.2	-1.2	-1.0
Father’s age at death	0.4	0.5	2.5	-0.6	-0.9	-0.7	-0.4	-0.7	-0.5	-0.3	-0.9	-0.7	-0.9	-1.0	-0.5	-0.2	-0.7	-0.6	-0.9	-1.6	-0.4	-0.1	-0.3	-0.8	-0.5	-0.4	-0.7	-0.5	-0.6
Loud music exposure frequency	0.4	0.5	2.0	0.7	-0.1	0.8	0.7	0.7	0.4	0.4	0.7	0.7	1.4	0.9	0.7	0.5	0.7	0.4	0.1	1.3	0.2	0.2	-0.4	0.8	0.7	0.5	0.9	0.6	0.8
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.4	-0.8	-1.2	-0.9	-0.5	-0.7	-0.8	-0.9	-0.8	-0.8	0.3	-0.6	-0.5	-0.8	-0.7	-0.7	-1.2	0.1	-1.1	-0.6	-1.2	-0.8	-0.7	-0.8	-0.9	-0.7	-0.8
Knee pain experienced in last month	0.4	0.6	2.0	0.8	1.0	0.9	0.9	0.7	0.4	0.0	0.7	0.7	1.4	0.8	0.7	0.7	0.7	0.7	0.6	0.5	0.6	0.7	-0.2	0.8	0.8	0.6	0.9	0.7	0.7
Hypertension (Self-reported)	0.4	1.0	9.7	0.9	-0.7	0.8	1.1	0.2	-0.7	3.1	0.2	0.3	-2.1	0.5	0.6	0.4	0.2	0.5	-0.9	0.5	1.4	-0.5	1.0	0.4	0.9	0.4	0.5	0.6	0.6
Smoking status: Previous	0.4	0.6	7.5	0.1	-0.4	0.0	0.3	-0.2	-0.7	2.2	-0.4	-0.1	-2.7	-0.1	0.1	-0.2	-0.2	-0.4	-0.2	-1.0	0.6	-0.1	0.9	-0.3	0.2	-0.0	-0.1	0.1	-0.0
Handedness (chirality/laterality): Left-handed	0.4	0.5	4.3	-0.6	-1.1	-0.6	-0.8	-0.6	-0.1	-0.9	-0.6	-0.6	-0.3	-0.7	-0.4	-0.2	-0.5	-0.9	-0.5	-2.1	-0.4	-0.1	-0.3	-0.6	-0.6	-0.5	-0.5	-0.5	-0.5
Medication: Aspirin	0.4	0.5	1.8	-0.6	-0.8	-0.7	-0.2	-0.8	-1.1	-0.1	-0.8	-0.9	-0.1	-0.2	-0.6	-0.3	-0.8	-0.6	-1.3	0.4	-0.9	-0.8	-1.2	-0.8	-0.5	-0.6	-0.8	-0.7	-0.7
Commuting to job workplace: Public transport	0.4	0.5	2.8	-0.5	-0.7	-0.6	-0.1	-0.7	-1.0	-0.6	-0.9	-0.7	-1.3	-0.4	-0.5	-0.6	-0.6	-0.8	-0.4	-1.7	-0.3	-0.3	0.0	-0.8	-0.3	-0.5	-0.7	-0.4	-0.5
Ever smoked	0.4	0.8	7.2	-0.0	-1.1	-0.2	-0.6	-0.1	0.2	2.3	-0.4	-0.0	-2.7	-0.6	-0.2	-0.4	-0.1	-0.7	0.5	-1.7	0.5	0.6	0.6	-0.5	-0.1	-0.1	-0.2	0.1	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	4.0	0.0	0.6	0.2	0.6	0.1	-0.5	-0.9	0.3	0.1	0.6	1.0	0.1	0.0	0.2	-0.0	0.0	2.0	-0.3	-1.1	-0.3	0.3	0.1	-0.0	0.2	-0.1	-0.1
Alzheimer’s Disease (including proxy)	0.3	0.4	1.3	-0.5	-0.9	-0.5	-0.5	-0.5	-0.8	-0.8	-0.4	-0.6	-0.1	-0.4	-0.6	-0.6	-0.5	-0.7	0.1	1.1	-0.7	-1.1	-0.4	-0.6	-0.5	-0.6	-0.5	-0.5	-0.5
Crohns Disease (2017)	0.3	0.8	1.6	-0.9	-0.5	-1.0	-0.7	-1.0	-1.3	0.0	-0.7	-0.9	-0.2	-0.4	-0.4	-1.0	-0.8	-1.0	-1.1	1.1	-1.1	-1.3	-0.5	-0.8	-0.8	-1.1	-1.0	-1.0	-0.7
Age at First Birth	0.3	0.4	2.1	0.3	-0.1	0.3	0.4	0.6	0.8	-0.1	0.6	0.5	0.6	0.8	0.4	0.3	0.4	0.5	1.4	1.2	0.7	-0.7	0.9	0.6	0.0	0.4	0.6	0.2	-0.0
Coronary Artery Disease (CAD)	0.3	0.3	1.9	-0.0	-1.0	-0.8	-0.5	-0.2	-0.5	0.5	0.3	-0.3	-0.5	0.1	-0.6	-0.4	0.6	-0.6	-1.4	0.6	-0.4	-0.2	-0.1	-0.6	-0.4	-0.6	-0.6	-0.6	-0.4
HDL Cholesterol	0.3	0.6	2.2	-0.7	-1.3	-0.7	-1.2	-0.8	-0.1	-1.5	-0.4	-0.7	0.6	-0.8	-0.5	-0.5	-0.5	-0.6	0.5	0.0	-1.0	-0.1	-0.8	-0.6	-0.9	-0.7	-0.3	-0.8	-0.6
Rheumatoid Arthritis	0.3	0.4	2.5	-0.6	-0.6	-0.4	-0.7	-0.5	-0.1	0.4	-0.2	-0.5	0.6	-0.1	-0.5	-0.4	-0.5	-0.5	-0.5	1.6	-0.6	-1.2	-0.5	-0.3	-0.7	-0.5	-0.4	-0.6	-0.5
Blood White Count	0.3	2.2	18.4	-0.8	-4.3	-1.1	-1.2	-1.2	-1.2	0.0	-1.6	-1.0	-1.6	-0.5	-1.2	-1.6	-1.2	-1.6	-1.6	-1.9	-0.7	0.4	-2.1	-1.4	-1.0	-1.3	-1.2	-0.9	-1.1
Hypothyroidism (self reported)	0.3	0.7	3.2	0.8	-0.4	0.8	1.0	0.8	0.7	0.6	0.9	0.8	0.7	1.0	0.4	1.0	0.7	0.9	0.2	1.8	0.4	0.8	-0.5	1.0	0.8	0.9	0.9	0.8	0.8
Hair Pigment	0.3	8.2	17.5	-3.2	-3.0	-3.2	-4.2	-2.9	-1.6	-0.8	-3.3	-3.0	-0.1	-4.0	-2.8	-3.2	-2.9	-3.7	-1.7	-2.1	-2.8	-1.0	-3.0	-3.3	-3.2	-3.1	-3.0	-2.8	-2.7
Medication: Metformin	0.3	0.5	3.6	0.8	0.3	0.5	1.1	0.6	-0.2	1.9	0.5	0.7	-0.6	1.0	0.6	0.2	0.6	0.6	0.2	0.5	0.6	-0.1	0.4	0.5	0.7	0.5	0.5	0.6	0.5
Maternal smoking around birth	0.3	0.4	3.4	0.4	0.5	0.2	0.7	0.3	0.0	1.8	0.3	0.4	-0.8	-0.1	0.5	0.5	0.3	0.7	-0.2	-0.6	-0.1	0.8	0.8	0.5	0.8	0.4	0.3	0.6	0.7
High blood pressure	0.3	0.9	7.3	0.9	-0.5	0.8	1.2	0.4	-0.4	2.7	0.3	0.5	-1.7	0.8	0.7	0.5	0.4	0.5	-0.7	0.6	1.4	-0.5	1.2	0.5	0.9	0.6	0.6	0.7	0.7
Stomach or abdominal pain in last month	0.3	0.3	1.6	0.7	0.4	0.4	0.7	0.5	0.0	0.7	0.3	0.5	-0.5	0.1	0.7	0.3	0.5	0.5	0.8	-0.8	0.7	1.3	-0.3	0.4	0.7	0.4	0.5	0.6	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.6	0.7	-0.4	0.4	0.7	0.7	0.3	-1.0	0.4	0.6	0.4	1.3	0.8	0.3	0.6	0.3	0.9	-0.1	0.2	1.1	-0.2	0.5	0.7	0.5	0.6	0.6	0.6
Time employed in main current job	0.3	0.3	2.4	-0.4	-0.6	-0.4	-0.1	-0.4	-0.8	-0.7	-0.4	-0.4	0.5	0.1	-0.3	-0.6	-0.4	-0.5	-0.1	1.6	-0.7	-1.0	-0.7	-0.2	-0.3	-0.6	-0.4	-0.5	-0.4
Medication: Lansoprazole	0.3	0.3	1.6	0.5	0.2	0.6	0.3	0.7	0.6	-0.3	0.5	0.6	0.3	0.5	0.4	0.4	0.6	0.6	0.6	0.1	0.9	1.3	0.5	0.5	0.5	0.5	0.6	0.5	0.6
Breastfed as a baby	0.3	0.4	1.1	-0.6	-1.1	-0.5	-0.8	-0.7	-0.5	-1.0	-0.5	-0.7	0.3	-0.7	-0.3	-0.7	-0.6	-0.5	-0.4	-0.3	-1.1	-0.7	-0.1	-0.6	-0.7	-0.7	-0.6	-0.7	-0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	3.7	0.7	-0.6	0.6	1.0	0.7	0.4	0.1	0.7	0.7	0.7	1.2	0.5	0.7	0.6	0.7	0.4	1.9	0.4	0.8	-0.7	0.7	0.7	0.7	0.7	0.6	0.7
Exposure to tobacco smoke outside home	0.3	0.4	2.8	-0.5	-0.2	-0.2	0.1	-0.4	-0.8	-1.0	-0.4	-0.3	0.4	0.7	-0.4	-0.3	-0.4	-0.6	-0.3	1.6	-0.3	-1.7	-0.8	-0.2	-0.3	-0.4	-0.2	-0.4	-0.5
Emphysema/chronic bronchitis	0.3	0.3	1.8	0.4	0.4	0.5	-0.2	0.5	1.1	0.3	0.4	0.6	-0.1	0.0	0.3	0.4	0.5	0.3	1.3	0.1	0.8	0.6	0.7	0.4	0.3	0.5	0.5	0.6	0.6
Medication: Aspirin	0.3	0.4	1.5	-0.5	-0.7	-0.6	-0.1	-0.7	-0.9	0.2	-0.7	-0.7	-0.4	-0.2	-0.5	-0.2	-0.7	-0.5	-1.2	0.6	-0.8	-0.6	-1.1	-0.7	-0.4	-0.5	-0.7	-0.6	-0.6
Loneliness, isolation	0.3	0.4	2.7	0.6	-0.3	0.5	0.9	0.4	-0.2	1.6	0.4	0.5	-0.3	1.0	0.3	0.4	0.4	0.5	0.3	0.3	0.5	0.1	1.0	0.4	0.8	0.4	0.3	0.6	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	3.5	0.4	-0.3	0.3	0.0	0.6	0.7	-0.4	0.3	0.5	-0.3	0.1	0.1	-0.1	0.6	0.4	0.6	-1.5	0.8	1.9	0.1	0.2	0.3	0.3	0.3	0.5	0.4
Back pain experienced in last month	0.3	0.4	1.1	0.7	0.6	0.6	1.0	0.5	-0.1	0.7	0.4	0.6	0.8	0.7	0.4	0.5	0.5	0.4	0.4	0.8	0.4	0.7	-0.6	0.7	0.8	0.5	0.6	0.6	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	0.5	0.7	0.7	0.8	0.4	-0.0	-0.6	0.5	0.4	0.2	0.2	0.8	0.4	0.5	0.7	0.3	-0.4	0.9	0.7	0.5	0.6	0.6	0.4	0.5	0.5	0.6
Vascular/heart problems diagnosed by doctor	0.3	0.9	8.6	-0.8	0.8	-0.7	-0.8	-0.2	0.4	-2.9	-0.1	-0.3	2.4	-0.4	-0.5	-0.3	-0.2	-0.4	0.6	-0.1	-1.4	0.1	-1.2	-0.2	-0.8	-0.4	-0.4	-0.6	-0.5
Neuroticism (Nagel 2018)	0.2	0.4	1.9	0.8	-0.7	0.3	0.9	0.4	-0.3	-0.2	0.5	0.6	0.1	1.4	0.8	0.2	0.8	0.7	0.5	-0.1	0.5	1.2	0.1	0.3	0.7	0.2	0.2	0.4	0.6
Irritable Bowel Disease (IBD)	0.2	0.5	1.3	0.7	0.7	0.5	0.6	0.7	0.6	0.8	0.8	0.7	0.6	0.6	1.1	0.8	0.7	0.7	0.2	0.6	0.3	0.8	0.9	0.8	0.9	0.6	0.6	0.8	1.1
Body Mass Index (BMI) (2010)	0.2	0.2	2.0	0.3	1.4	0.4	0.5	0.3	0.1	-0.0	0.3	0.3	0.5	0.0	0.1	0.4	0.3	0.6	-0.6	0.8	0.7	0.0	0.1	0.4	0.4	0.3	0.3	0.3	0.3
Neuroticism (2016)	0.2	0.3	1.1	-0.2	-0.7	-0.4	0.3	-0.5	-1.1	0.2	-0.4	-0.4	-0.3	0.6	-0.1	-0.9	-0.3	-0.3	-0.7	0.8	-0.4	-0.7	-0.8	-0.5	-0.3	-0.8	-0.6	-0.7	-0.6
Blood Platelet Count	0.2	1.9	12.6	-1.1	-3.5	-1.1	-1.4	-1.2	-1.0	-0.2	-1.6	-1.3	-0.7	-2.0	-1.1	-1.4	-1.4	-1.3	-0.9	-1.3	-1.1	0.8	-1.6	-1.4	-1.0	-1.3	-1.2	-0.9	-0.9
Neuroticism	0.2	0.4	1.7	0.9	-0.0	0.7	0.9	0.7	0.2	-0.0	0.5	0.7	0.1	1.3	0.8	0.3	0.7	0.8	0.5	0.1	0.7	0.9	0.4	0.5	0.9	0.6	0.7	0.7	0.7
Medication for hormone replacement therapy	0.2	0.2	1.1	-0.4	0.0	-0.2	-0.4	-0.2	-0.0	-0.7	-0.4	-0.3	-0.4	-1.0	-0.3	-0.3	-0.3	-0.3	0.0	-1.1	0.1	0.6	-0.1	-0.3	-0.3	-0.3	-0.2	-0.2	-0.2
Medication: Levothyroxine sodium	0.2	0.3	3.3	0.3	-0.5	0.2	0.4	0.3	0.0	-0.7	0.3	0.3	1.0	0.8	0.1	0.2	0.2	0.4	0.4	1.8	-0.4	0.4	-1.0	0.3	0.2	0.2	0.3	0.2	0.2
Chronic bronchitis/emphysema (father)	0.2	0.3	1.8	-0.1	-0.2	-0.2	0.3	-0.5	-1.1	-0.5	-0.5	-0.4	-0.2	-0.2	-0.3	-0.2	-0.5	-0.1	-1.4	-0.8	-0.5	-0.1	-0.6	-0.3	-0.0	-0.4	-0.3	-0.3	-0.3
Mouth/teeth dental problems	0.2	0.3	1.5	0.2	0.6	0.4	0.0	0.5	1.0	0.2	0.6	0.4	0.5	-0.4	0.3	0.5	0.5	0.3	0.5	-1.2	0.4	0.8	0.1	0.5	0.2	0.5	0.5	0.3	0.4
Medication: Ramipril	0.2	0.2	1.1	0.4	0.2	0.4	0.6	0.1	0.0	0.4	0.0	0.1	-0.7	-0.2	0.1	0.6	0.1	0.7	-0.4	0.1	0.4	1.0	-0.0	0.2	0.7	0.4	0.3	0.5	0.6
Trunk fat-free mass	0.2	1.2	6.5	-0.7	-0.1	-1.0	-0.9	-1.0	-1.1	2.5	-1.2	-0.8	-0.0	-1.6	-1.7	-1.2	-1.0	-0.7	-0.5	-1.3	-0.4	-0.1	-1.7	-1.1	-0.9	-1.1	-1.1	-0.9	-0.9
Alcohol intake versus 10 years previously	0.2	0.3	2.2	0.3	0.0	0.3	0.9	0.4	-0.2	-0.3	0.3	0.4	1.2	0.7	0.1	0.0	0.3	0.4	-0.2	1.5	0.4	-0.1	-0.7	0.4	0.4	0.3	0.2	0.2	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	1.8	0.5	-0.5	0.2	0.3	0.3	0.5	-0.1	-0.0	0.3	-0.4	0.0	0.4	0.5	0.3	-0.1	0.5	-1.3	0.6	0.9	0.5	0.1	0.6	0.5	0.3	0.7	0.6
Medication: Cholesterol lowering	0.2	0.3	3.4	0.3	-0.7	0.1	0.1	0.3	0.5	-0.3	0.5	0.3	0.6	1.1	0.5	0.3	0.4	0.3	0.0	1.8	-0.2	-0.1	0.3	0.3	0.2	0.3	0.2	0.3	0.4
Prospective memory result	0.2	0.2	1.2	-0.3	0.9	-0.3	-0.9	-0.2	0.6	-0.0	-0.1	-0.2	1.1	-0.8	-0.3	-0.1	-0.3	0.0	-0.2	-0.7	-0.2	0.5	-0.3	-0.2	-0.5	-0.2	-0.2	-0.2	-0.1
Trunk predicted mass	0.2	1.2	6.5	-0.7	-0.1	-1.0	-0.8	-1.0	-1.1	2.5	-1.2	-0.8	-0.0	-1.6	-1.7	-1.2	-1.0	-0.7	-0.5	-1.3	-0.3	-0.1	-1.7	-1.1	-0.9	-1.1	-1.1	-0.9	-0.9
Length of working week for main job	0.2	0.2	1.4	0.3	0.9	0.2	0.6	-0.1	-0.6	-0.2	-0.1	0.0	1.2	0.1	0.1	0.3	-0.1	0.2	0.3	0.7	-0.5	-0.2	-0.6	0.2	0.3	-0.0	0.2	0.0	0.2
Medication: Paracetamol	0.2	0.4	1.6	-0.4	-1.3	-0.5	0.1	-0.5	-1.2	0.1	-0.9	-0.5	-0.2	-0.6	-0.1	-0.8	-0.6	-0.4	-0.4	0.5	-0.9	-0.0	-1.0	-0.6	-0.2	-0.6	-0.6	-0.3	-0.4
Glaucoma (self-reported)	0.2	0.2	1.4	-0.4	-1.2	-0.2	0.0	-0.6	-0.9	0.4	-0.5	-0.5	-0.6	-0.6	-0.5	-0.4	-0.6	-0.1	-0.4	-0.3	-0.2	-0.3	0.2	-0.4	-0.3	-0.4	-0.4	-0.4	-0.4
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.8	0.2	0.4	0.2	0.1	0.5	0.9	0.2	0.5	0.5	0.8	0.5	0.5	0.1	0.6	0.2	0.5	-0.8	0.3	0.3	0.1	0.4	0.2	0.3	0.4	0.4	0.3
High blood pressure (siblings)	0.2	0.3	1.0	0.6	0.4	0.6	0.8	0.4	0.1	-0.7	0.2	0.4	-0.0	0.9	0.3	0.7	0.4	0.5	0.5	-0.1	1.0	1.0	-0.3	0.4	0.8	0.6	0.5	0.7	0.7
Medication for pain relief, constipation, heartburn	0.2	0.3	1.5	-0.4	0.9	-0.3	-0.6	-0.3	0.2	-0.8	0.3	-0.2	0.8	0.4	-0.5	0.0	-0.1	-0.3	0.0	0.9	-0.5	-1.2	-0.0	-0.1	-0.7	-0.2	-0.2	-0.6	-0.5
Heart disease (mother)	0.2	0.2	2.0	-0.0	-1.4	-0.1	-0.2	-0.1	-0.0	-1.1	-0.1	-0.1	0.1	0.4	-0.2	0.0	-0.1	-0.3	-0.4	0.7	-0.2	0.4	-1.1	-0.1	-0.0	-0.1	-0.1	-0.0	0.0
Arm predicted mass (right)	0.2	0.9	4.7	-0.5	0.6	-0.7	-0.4	-0.8	-1.3	2.2	-0.9	-0.6	0.9	-1.1	-1.4	-1.1	-0.8	-0.6	-0.5	-0.5	-0.3	-0.4	-2.0	-0.8	-0.6	-1.0	-0.8	-0.8	-0.8
Illnesses of father: Heart disease	0.2	0.3	2.1	0.6	-0.4	0.1	0.2	0.6	0.9	0.3	0.4	0.5	-0.7	0.2	0.3	0.5	0.6	0.4	0.8	0.0	0.1	1.5	0.3	0.3	0.5	0.5	0.3	0.6	0.6
Whole body fat-free mass	0.2	0.9	6.8	-0.3	0.3	-0.7	-0.4	-0.7	-1.0	2.6	-1.0	-0.5	0.0	-1.5	-1.3	-0.9	-0.7	-0.4	-0.5	-1.5	0.0	0.3	-1.6	-0.8	-0.4	-0.8	-0.7	-0.5	-0.6
Friendships satisfaction	0.2	0.3	1.8	0.0	-0.9	-0.3	0.1	-0.2	-0.5	1.3	-0.4	-0.2	-1.2	0.3	0.1	-0.2	-0.2	-0.4	-0.8	-1.3	-0.2	0.1	-0.1	-0.3	0.1	-0.2	-0.2	-0.0	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.3	1.5	0.1	1.1	0.5	0.2	0.4	0.3	0.2	0.7	0.4	0.3	0.7	0.5	-0.1	0.5	0.3	1.2	-0.2	0.9	-0.9	0.9	0.5	-0.0	0.2	0.4	0.0	-0.1
Eye problems/disorders: Glaucoma	0.2	0.2	0.9	-0.3	-1.0	-0.1	-0.0	-0.5	-0.8	0.4	-0.3	-0.4	-0.6	-0.5	-0.4	-0.4	-0.5	-0.1	-0.2	-0.5	-0.3	-0.1	0.5	-0.2	-0.2	-0.4	-0.3	-0.3	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.7	-0.4	-0.6	-0.5	-0.1	-0.5	-0.8	0.7	-0.6	-0.5	0.3	-0.4	-0.6	-0.5	-0.6	-0.6	-0.7	0.1	-0.5	-0.6	-0.7	-0.4	-0.4	-0.5	-0.5	-0.5	-0.5
Irritability	0.2	0.3	1.1	-0.3	-0.6	-0.4	-0.4	-0.4	-0.7	-0.1	-0.9	-0.3	-1.1	-0.0	-0.4	-0.8	-0.5	-0.7	-0.1	-0.9	-0.1	0.2	-0.8	-0.7	-0.3	-0.5	-0.4	-0.3	-0.5
Fractured/broken bones in last 5 years	0.2	0.3	2.1	-0.0	-0.5	-0.2	-0.6	-0.3	-0.0	1.2	-0.4	-0.2	-0.6	-1.1	-0.1	-0.4	-0.2	-0.2	0.0	-1.4	0.1	0.0	0.0	-0.4	-0.2	-0.2	-0.4	-0.1	-0.1
Major Depression (MDD)	0.1	0.2	1.7	0.2	-1.3	0.0	0.7	0.1	-0.6	-0.2	0.2	0.1	0.7	0.6	0.0	0.0	0.1	-0.1	-0.8	0.1	-0.3	0.3	-0.1	0.2	0.3	-0.1	0.1	0.0	0.2
Prostate Cancer	0.1	0.2	1.1	-0.4	-1.0	-0.4	-0.9	-0.2	0.2	-0.5	-0.3	-0.3	-0.4	-0.3	0.1	-0.3	-0.3	-0.9	-0.2	-0.5	-0.5	0.1	-0.1	-0.4	-0.4	-0.2	-0.2	-0.2	-0.2
Mean Putamen Volume	0.1	0.1	0.5	-0.2	0.4	-0.2	-0.3	-0.2	-0.1	-0.4	0.1	-0.1	0.6	0.1	-0.2	-0.2	-0.1	-0.3	0.5	0.7	-0.3	-0.6	-0.2	-0.1	-0.3	-0.3	-0.1	-0.4	-0.3
Systolic Blood Pressure	0.1	0.7	5.3	0.1	0.6	0.2	0.2	-0.4	-0.5	1.4	-0.1	-0.3	-1.7	-0.1	-0.5	0.3	-0.3	0.5	-1.5	2.3	1.1	-1.2	0.5	-0.1	-0.1	-0.1	-0.1	-0.2	-0.2
Lung FEV1/FVC ratio	0.1	0.3	3.0	-0.2	1.7	0.0	0.1	0.2	0.1	-1.0	0.3	0.1	1.4	0.0	0.2	0.1	0.2	-0.0	0.2	0.5	0.1	-1.2	-0.7	0.2	-0.3	-0.1	0.1	-0.4	-0.4
Tanning	0.1	1.7	3.6	1.2	1.9	1.2	1.5	1.3	1.2	-1.1	1.4	1.2	1.5	1.1	1.1	1.7	1.2	1.7	0.4	-0.5	0.8	1.7	0.7	1.5	1.3	1.4	1.4	1.3	1.3
Sensitivity / hurt feelings	0.1	0.1	0.5	0.3	-0.2	0.2	0.0	0.2	0.0	-0.4	0.1	0.2	-0.4	0.7	0.3	-0.2	0.2	-0.0	0.7	-0.5	0.6	0.3	-0.0	0.1	0.1	-0.0	0.2	0.1	0.1
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.5	0.4	0.3	0.3	0.3	0.5	0.5	0.3	0.6	0.5	0.3	0.7	0.6	0.2	0.5	0.4	0.6	0.4	0.3	0.2	0.5	0.4	0.4	0.3	0.3	0.4	0.5
Supplements: Zinc	0.1	0.1	0.9	0.1	-0.2	0.0	-0.1	-0.1	0.0	0.8	-0.1	0.0	-0.9	-0.4	-0.0	0.2	-0.0	-0.1	0.2	-0.4	0.5	0.2	0.2	-0.2	-0.1	0.0	-0.1	-0.0	-0.1
Leg fat-free mass (left)	0.1	0.8	7.5	0.8	1.1	0.5	0.9	0.4	-0.2	2.7	-0.1	0.5	0.2	-0.7	-0.0	0.2	0.3	0.7	0.1	-1.6	1.1	1.2	-0.8	0.3	0.9	0.4	0.4	0.7	0.6
Average weekly fortified wine intake	0.1	0.1	0.7	-0.1	-0.2	-0.1	-0.0	-0.3	-0.4	-0.8	-0.3	-0.3	0.5	-0.6	-0.1	-0.3	-0.2	-0.3	0.1	-0.6	0.1	-0.1	0.1	-0.2	-0.0	-0.3	-0.3	-0.2	-0.1
Relative age voice broke	0.1	0.1	0.9	0.1	1.0	-0.1	0.1	-0.0	-0.1	-0.8	0.0	-0.0	-0.2	-0.2	0.2	0.1	0.0	0.3	-0.1	-0.8	-0.3	0.2	0.3	0.1	0.1	0.0	0.1	0.1	0.1
Leg predicted mass (left)	0.1	0.7	7.1	0.8	1.1	0.4	0.9	0.4	-0.3	2.7	-0.1	0.5	0.2	-0.7	-0.1	0.2	0.3	0.7	0.1	-1.5	1.0	1.2	-0.9	0.3	0.8	0.4	0.3	0.7	0.6
Had other major operations	0.1	0.1	1.4	0.1	0.1	0.2	0.0	0.0	-0.2	1.2	0.1	0.1	-0.2	-0.3	0.2	-0.2	0.2	0.2	0.1	0.6	0.5	-0.4	0.6	0.1	0.1	-0.0	0.0	0.1	0.1
Hip circumference	0.1	0.6	4.2	0.5	1.4	0.2	0.7	0.3	-0.2	1.8	0.1	0.4	2.0	-0.1	0.2	0.0	0.3	0.2	-0.3	0.5	0.5	0.2	-1.6	0.3	0.5	0.2	0.1	0.3	0.4
Worrier / anxious feelings	0.1	0.3	3.1	0.1	-1.0	-0.1	0.0	-0.0	-0.3	-1.8	-0.0	-0.1	0.9	0.8	0.2	-0.3	-0.1	-0.4	0.0	0.0	-0.3	0.0	-0.8	0.0	-0.0	-0.2	-0.0	-0.2	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.8	-0.3	-0.4	-0.4	0.0	-0.2	-0.3	-0.7	-0.4	-0.2	0.4	0.5	-0.2	-0.3	-0.2	-0.4	-0.9	-0.7	-0.6	0.1	-0.6	-0.2	-0.2	-0.2	-0.4	-0.1	-0.2
Mouth/teeth dental problems: Dentures	0.1	0.1	1.2	0.2	0.6	0.1	0.3	-0.0	-0.5	1.1	-0.1	0.1	-0.3	0.4	-0.3	-0.1	-0.1	0.3	-0.2	0.8	0.3	-0.6	0.3	-0.1	0.1	0.0	-0.1	0.0	-0.0
Illnesses of mother	0.1	0.2	1.7	-0.0	0.8	0.0	-0.1	0.1	0.2	0.8	0.3	0.1	-0.2	0.0	-0.0	-0.0	0.1	0.3	0.7	-0.3	-0.3	-0.2	1.3	0.2	-0.0	0.0	0.2	0.0	0.0
Hair/balding pattern: Pattern 4	0.1	0.2	1.1	-0.4	-0.8	-0.3	-0.7	-0.2	0.1	0.5	-0.2	-0.2	-1.1	-0.4	0.1	-0.5	-0.2	-0.2	0.3	-0.1	-0.0	-0.7	0.6	-0.4	-0.6	-0.3	-0.2	-0.3	-0.4
Pulse wave reflection index	0.1	0.1	0.7	-0.1	0.1	-0.1	-0.4	-0.0	0.3	0.1	-0.1	-0.0	-0.0	-0.0	0.1	-0.2	-0.0	0.3	0.1	-0.7	-0.1	-0.3	0.8	-0.2	-0.0	-0.1	-0.0	0.0	0.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.9	0.3	0.2	0.3	0.3	0.1	-0.0	-1.0	-0.0	0.0	0.7	0.3	0.5	0.3	-0.0	0.1	-0.4	-0.4	-0.1	0.7	-0.8	0.2	0.2	0.2	0.3	0.1	0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	1.5	0.2	-0.0	0.2	0.4	0.1	-0.3	-0.8	-0.0	0.0	-0.5	0.7	0.3	0.0	-0.0	0.0	0.4	1.2	0.1	-0.1	-0.1	0.1	0.2	0.1	0.1	0.1	-0.0
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	1.4	0.0	1.0	0.3	0.0	0.2	0.3	-0.8	0.1	0.2	0.9	-0.4	-0.0	0.3	0.1	0.1	0.7	-1.2	0.1	0.7	-0.4	0.2	0.1	0.1	0.2	0.1	0.1
Arm fat-free mass (right)	0.1	0.7	5.6	-0.3	0.8	-0.5	-0.2	-0.6	-1.0	2.4	-0.7	-0.4	1.0	-1.0	-1.2	-0.9	-0.6	-0.4	-0.3	-0.4	0.1	-0.3	-1.8	-0.5	-0.5	-0.7	-0.6	-0.6	-0.6
Number of children fathered	0.1	0.1	1.0	0.1	0.3	0.0	-0.2	0.2	0.2	-0.5	0.1	0.2	-0.2	-0.1	0.1	-0.4	0.2	-0.3	0.4	-1.0	0.3	0.3	-0.6	0.0	-0.1	-0.0	0.2	0.0	-0.1
Eye problems/disorders: None of the above	0.1	0.1	0.5	0.3	0.5	0.1	0.1	0.3	0.3	0.2	0.6	0.3	0.7	0.2	0.3	0.1	0.4	0.2	-0.1	0.2	-0.2	-0.5	0.5	0.4	0.2	0.1	0.3	0.1	0.2
Had major operations	0.1	0.1	1.7	-0.1	-0.2	-0.3	-0.3	-0.1	-0.1	-0.5	-0.3	-0.1	-0.1	-0.1	-0.1	-0.5	-0.0	-0.4	-0.0	-1.3	0.1	0.3	-0.4	-0.3	-0.1	-0.2	-0.3	-0.1	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.3	-0.3	-0.3	-0.2	-0.2	-0.4	-0.4	0.1	-0.4	-0.3	-0.6	-0.1	-0.3	-0.2	-0.2	-0.3	-0.1	0.4	-0.0	-0.4	0.1	-0.4	-0.2	-0.3	-0.3	-0.3	-0.2
Leg fat-free mass (right)	0.1	0.8	7.6	0.5	0.8	0.2	0.6	0.1	-0.4	2.8	-0.4	0.2	-0.3	-1.2	-0.3	-0.1	0.0	0.4	-0.1	-2.1	1.0	1.3	-1.0	-0.1	0.6	0.1	0.1	0.5	0.3
Commuting to job workplace: Walk	0.1	0.1	0.6	0.2	-0.2	0.4	0.2	0.2	0.1	-0.5	0.1	0.1	-0.3	0.6	0.6	0.2	0.2	0.0	0.4	0.2	0.7	-0.2	0.6	0.1	0.3	0.2	0.2	0.3	0.2
Eye problems/disorders: Cataract	0.1	0.1	0.5	-0.4	-0.2	-0.5	-0.2	-0.3	-0.3	-0.4	-0.5	-0.4	-0.0	-0.2	-0.3	-0.3	-0.3	-0.2	-0.4	0.4	-0.4	0.3	-0.7	-0.5	-0.2	-0.2	-0.4	-0.1	-0.2
Osteoarthritis (self-reported)	0.1	0.2	1.6	0.1	-0.6	0.2	-0.1	0.0	0.2	0.5	0.2	0.1	1.0	0.5	-0.1	0.1	-0.0	0.1	0.3	1.3	-0.2	-0.4	-0.3	0.2	-0.1	-0.0	0.2	-0.0	0.1
Whole body water mass	0.1	0.8	7.3	-0.2	0.4	-0.5	-0.3	-0.6	-0.9	2.7	-0.9	-0.4	0.0	-1.5	-1.2	-0.8	-0.6	-0.3	-0.4	-1.6	0.2	0.5	-1.5	-0.7	-0.3	-0.6	-0.6	-0.4	-0.4
Leg predicted mass (right)	0.1	0.8	7.4	0.5	0.8	0.2	0.6	0.1	-0.4	2.7	-0.4	0.2	-0.2	-1.2	-0.3	-0.1	0.1	0.5	-0.0	-2.1	1.0	1.3	-1.0	-0.1	0.6	0.1	0.1	0.5	0.3
Miserableness	0.1	0.2	0.8	0.3	-0.3	0.1	-0.2	0.4	0.7	0.3	0.3	0.4	-0.5	0.3	0.1	-0.1	0.4	0.3	0.8	-0.0	0.5	0.9	0.4	0.2	0.1	0.3	0.2	0.3	0.3
Mother’s age at death	0.1	0.2	1.7	0.1	0.1	0.2	0.2	0.1	0.3	-0.4	-0.1	0.1	-0.3	-0.1	0.0	0.5	0.1	0.1	0.3	-1.3	0.7	0.8	0.2	0.0	0.2	0.3	0.2	0.3	0.2
Medication: Paracetamol	0.1	0.1	0.4	0.2	-0.4	0.3	0.6	0.1	-0.5	0.2	-0.2	0.0	0.3	-0.2	0.5	0.0	-0.1	0.2	0.3	0.5	-0.0	0.5	-0.3	0.1	0.4	0.1	0.2	0.2	0.2
Medication: Atorvastatin	0.1	0.2	2.7	0.1	-0.1	0.0	0.1	0.2	0.2	-0.0	0.3	0.2	0.1	0.9	0.2	0.3	0.2	0.2	0.3	1.6	-0.0	-0.2	-0.1	0.1	0.0	0.2	0.1	0.1	0.0
Basal metabolic rate	0.1	0.6	8.1	0.2	0.8	-0.1	0.2	-0.2	-0.6	2.8	-0.5	0.0	0.4	-0.9	-0.7	-0.4	-0.2	0.1	-0.1	-1.2	0.6	0.6	-1.3	-0.2	0.2	-0.2	-0.2	0.0	-0.0
Arm fat-free mass (left)	0.1	0.6	5.7	-0.2	0.8	-0.4	-0.2	-0.4	-0.8	2.4	-0.6	-0.3	1.0	-1.0	-1.0	-0.7	-0.5	-0.2	-0.2	-0.7	0.2	-0.0	-1.6	-0.4	-0.3	-0.6	-0.4	-0.4	-0.4
Arm predicted mass (left)	0.1	0.5	6.4	0.1	1.1	-0.1	0.1	-0.2	-0.5	2.5	-0.3	-0.0	1.2	-0.8	-0.7	-0.4	-0.2	-0.0	0.0	-0.5	0.3	0.2	-1.4	-0.2	-0.0	-0.3	-0.2	-0.1	-0.1
Systolic blood pressure, automated reading	0.0	0.1	1.0	0.1	0.3	0.2	0.2	-0.2	-0.2	0.2	-0.1	-0.2	-0.6	-0.1	-0.2	0.5	-0.2	0.4	-1.0	1.0	0.6	-0.2	0.2	-0.1	0.0	0.0	-0.0	-0.0	0.1
Had menopause	0.0	0.0	0.3	-0.1	-0.3	0.0	-0.1	-0.1	-0.1	0.1	-0.0	-0.1	0.0	-0.5	0.0	-0.1	-0.1	-0.0	0.1	-0.2	-0.0	-0.3	-0.1	-0.0	-0.1	-0.2	-0.1	-0.1	-0.1
Neuroticism score	0.0	0.1	0.7	0.2	-0.7	-0.0	0.1	0.1	-0.1	-0.8	0.0	0.1	0.1	0.8	0.1	-0.2	0.1	0.1	0.2	0.7	-0.0	0.1	-0.2	-0.0	0.1	-0.1	0.0	0.0	0.1
Diastolic blood pressure, automated reading	0.0	0.1	0.5	-0.2	0.0	-0.0	-0.1	-0.3	-0.1	0.2	-0.2	-0.3	-0.4	-0.6	-0.6	0.2	-0.2	0.2	-0.7	0.5	0.4	-0.1	-0.1	-0.3	-0.0	-0.1	-0.2	-0.1	0.1