[Hub]/) : Traits : Comparative height size at age 10 :

chr9:97,520,168-101,477,500

Best TWAS P=1.84e-16 · Best GWAS P=3.78e-34 conditioned to 1.1e-30

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC441454 0.05 0.01 lasso 3 0.02 1.5e-03 5.9 5.8 6.8e-09 0.07 0.04 0.55 FALSE
2 GTEx Adipose Subcutaneous HSD17B3 0.21 0.01 enet 31 0.04 1.9e-04 6.4 5.8 5.7e-09 0.05 0.32 0.20 FALSE
3 GTEx Adipose Visceral Omentum C9orf156 0.19 0.15 lasso 4 0.11 1.6e-06 -5.3 -5.5 4.5e-08 0.05 0.45 0.51 FALSE
4 GTEx Artery Tibial RP11-435O5.5 0.09 0.04 lasso 2 0.02 7.3e-03 8.2 -8.0 9.6e-16 -0.03 0.24 0.09 TRUE
5 GTEx Brain Cerebellar Hemisphere C9orf156 0.26 0.22 lasso 2 0.14 1.9e-04 -5.3 -5.3 1.1e-07 0.05 0.13 0.51 FALSE
6 GTEx Brain Cerebellum C9orf156 0.30 0.27 lasso 7 0.24 8.1e-08 -4.9 -5.2 2.1e-07 0.04 0.54 0.40 FALSE
7 GTEx Brain Cortex C9orf156 0.51 0.32 enet 11 0.29 8.1e-09 -5.3 -6.0 2.5e-09 0.05 0.50 0.47 FALSE
8 GTEx Brain Frontal Cortex BA9 C9orf156 0.15 0.28 lasso 1 0.26 1.1e-07 -5.3 -5.3 1.1e-07 0.05 0.33 0.39 FALSE
9 GTEx Breast Mammary Tissue CDC14B 0.16 0.02 enet 21 0.02 3.7e-02 8.0 -7.0 2.0e-12 -0.06 0.06 0.86 FALSE
10 GTEx Breast Mammary Tissue ERCC6L2 0.17 0.02 lasso 4 0.03 1.2e-02 2.5 5.6 2.3e-08 -0.14 0.28 0.04 TRUE
11 GTEx Breast Mammary Tissue (Male) C9orf156 0.13 -0.01 enet 1 -0.01 5.6e-01 -5.3 -5.3 1.1e-07 0.05 0.05 0.07 FALSE
12 GTEx Breast Mammary Tissue (Female) C9orf156 0.42 0.22 lasso 10 0.23 1.5e-07 -5.3 -6.7 1.8e-11 0.02 0.06 0.87 FALSE
13 GTEx Cells EBV-transformed lymphocytes AAED1 0.17 0.02 lasso 3 0.04 2.4e-02 7.8 7.3 3.9e-13 0.06 0.05 0.44 FALSE
14 GTEx Cells Transformed fibroblasts RP11-435O5.5 0.14 0.04 lasso 4 0.02 7.9e-03 5.1 -5.1 2.9e-07 0.07 0.36 0.03 FALSE
15 GTEx Heart Left Ventricle C9orf156 0.23 0.18 enet 13 0.16 9.3e-09 -5.3 -5.4 5.1e-08 0.05 0.55 0.45 FALSE
16 GTEx Liver PTCH1 0.25 0.06 enet 11 0.03 4.9e-02 6.3 5.2 2.0e-07 0.17 0.16 0.09 FALSE
17 GTEx Nerve Tibial HSD17B3 0.14 0.00 enet 20 0.00 2.4e-01 7.7 7.6 2.8e-14 0.11 0.09 0.34 FALSE
18 GTEx Nerve Tibial ZNF367 0.10 0.05 lasso 3 0.02 7.9e-03 8.1 7.7 1.1e-14 0.05 0.04 0.94 FALSE
19 GTEx Ovary C9orf156 0.39 0.23 enet 15 0.18 3.9e-05 -5.3 -6.5 8.5e-11 0.03 0.21 0.29 FALSE
20 GTEx Stomach C9orf156 0.18 0.19 lasso 1 0.18 5.9e-09 -5.3 -5.3 1.1e-07 0.05 0.54 0.44 FALSE
21 GTEx Testis HABP4 0.19 0.22 lasso 9 0.21 1.1e-09 7.9 7.9 3.3e-15 0.05 0.07 0.93 FALSE
22 GTEx Testis C9orf156 0.39 0.40 enet 14 0.41 1.1e-19 -5.3 -5.3 1.2e-07 0.06 0.52 0.48 FALSE
23 GTEx Thyroid CDC14B 0.15 0.10 lasso 5 0.08 5.3e-07 7.5 -7.4 1.7e-13 -0.09 0.20 0.80 FALSE
24 GTEx Thyroid C9orf156 0.21 0.26 lasso 1 0.26 7.9e-20 -5.3 -5.3 1.1e-07 0.05 0.46 0.54 FALSE
25 METSIM Adipose ANP32B 0.05 0.03 lasso 6 0.02 1.1e-03 -6.2 6.3 4.0e-10 0.04 0.00 0.99 FALSE
26 METSIM Adipose C9orf156 0.15 0.17 lasso 5 0.17 4.3e-25 -5.3 -5.3 1.0e-07 0.06 0.44 0.56 FALSE
27 METSIM Adipose ERCC6L2 0.06 0.01 bslmm 569 0.03 4.6e-05 6.9 -5.2 2.2e-07 0.20 0.16 0.11 TRUE
28 YFS Blood ANP32B 0.03 0.02 lasso 9 0.02 1.9e-08 -6.2 7.0 2.2e-12 0.05 0.00 1.00 TRUE
29 YFS Blood HABP4 0.08 0.09 enet 24 0.11 5.9e-34 8.2 -7.8 7.3e-15 -0.01 0.02 0.98 FALSE
30 The Cancer Genome Atlas Breast Invasive Carcinoma CDC14B 0.02 0.01 lasso 1 0.01 3.0e-03 8.0 -8.0 1.2e-15 -0.05 0.03 0.59 FALSE
31 The Cancer Genome Atlas Glioblastoma Multiforme CDC14B 0.16 0.17 blup 41 0.19 2.6e-06 7.8 -7.3 3.9e-13 -0.06 0.05 0.92 FALSE
32 The Cancer Genome Atlas Glioblastoma Multiforme HABP4 0.08 0.06 blup 44 0.05 1.6e-02 7.5 -8.2 1.8e-16 -0.04 0.03 0.49 TRUE
33 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HABP4 0.02 0.02 blup 44 0.02 7.1e-03 7.8 8.1 6.2e-16 0.05 0.03 0.67 FALSE
34 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CDC14B 0.03 0.02 blup 42 0.02 2.1e-03 7.8 -8.0 9.0e-16 -0.04 0.04 0.58 FALSE
35 The Cancer Genome Atlas Brain Lower Grade Glioma C9orf156 0.18 0.23 lasso 4 0.23 1.9e-25 -5.3 -5.4 5.5e-08 0.04 0.00 1.00 FALSE
36 The Cancer Genome Atlas Brain Lower Grade Glioma CDC14B 0.05 0.06 lasso 5 0.06 6.5e-07 7.7 -7.2 7.9e-13 -0.06 0.12 0.88 FALSE
37 The Cancer Genome Atlas Brain Lower Grade Glioma HABP4 0.05 0.08 lasso 5 0.08 6.9e-09 7.6 -7.7 1.4e-14 -0.06 0.11 0.89 FALSE
38 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C9orf156 0.07 0.03 lasso 2 0.03 2.1e-04 -5.3 -5.2 1.6e-07 0.04 0.00 0.99 FALSE
39 The Cancer Genome Atlas Prostate Adenocarcinoma PTCH1 0.02 0.01 blup 54 0.02 1.1e-03 7.4 -7.1 1.0e-12 0.07 0.06 0.04 FALSE
40 The Cancer Genome Atlas Stomach Adenocarcinoma CDC14B 0.08 0.02 blup 41 0.04 1.0e-03 5.9 -8.1 6.6e-16 0.00 0.02 0.60 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma CDC14B 0.05 0.07 blup 42 0.08 4.8e-08 8.1 -7.9 3.2e-15 -0.04 0.05 0.95 FALSE