[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr10:101,548,177-103,428,898

Best TWAS P=1.09e-29 · Best GWAS P=5.57e-28 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Artery Tibial	RP11-179B2.2	0.11	0.09	lasso	4	0.08	8.8e-07	10.9	11.3	1.1e-29	0.96	0.00	1.00	TRUE
29	YFS	Blood	HIF1AN	0.06	0.06	lasso	30	0.07	2.5e-22	-5.1	5.9	3.0e-09	0.06	1.00	0.00	TRUE
15	GTEx	Heart Left Ventricle	RP11-179B2.2	0.15	0.18	enet	2	0.14	4.8e-08	11.0	11.0	6.0e-28	1.00	0.00	1.00	FALSE
16	GTEx	Lung	RP11-179B2.2	0.18	0.12	lasso	3	0.12	1.7e-09	11.0	11.0	6.5e-28	0.99	0.00	1.00	FALSE
4	GTEx	Artery Aorta	RP11-179B2.2	0.16	0.11	lasso	2	0.09	7.6e-06	10.9	10.9	6.7e-28	0.99	0.00	1.00	FALSE
3	GTEx	Adipose Visceral Omentum	RP11-179B2.2	0.13	0.02	lasso	3	0.03	6.5e-03	11.0	10.9	7.1e-28	0.99	0.00	0.99	FALSE
9	GTEx	Brain Frontal Cortex BA9	RP11-179B2.2	0.22	0.15	lasso	2	0.11	7.2e-04	11.0	10.9	2.0e-27	0.98	0.01	0.97	FALSE
8	GTEx	Brain Cerebellum	RP11-179B2.2	0.37	0.21	lasso	4	0.20	1.4e-06	11.0	10.8	2.2e-27	0.96	0.00	0.99	FALSE
1	GTEx	Adipose Subcutaneous	RP11-179B2.2	0.15	0.08	lasso	6	0.08	3.2e-07	9.9	10.8	3.8e-27	0.90	0.02	0.98	FALSE
10	GTEx	Breast Mammary Tissue	RP11-179B2.2	0.11	0.09	lasso	2	0.07	1.8e-04	11.0	10.8	4.8e-27	0.96	0.01	0.99	FALSE
13	GTEx	Esophagus Muscularis	RP11-179B2.2	0.15	0.16	lasso	3	0.16	8.1e-10	10.7	10.7	1.0e-26	0.98	0.01	0.99	FALSE
24	GTEx	Thyroid	RP11-179B2.2	0.18	0.12	lasso	7	0.11	8.3e-09	9.9	10.5	8.9e-26	0.91	0.05	0.95	FALSE
44	The Cancer Genome Atlas	Brain Lower Grade Glioma	SEMA4G	0.03	0.01	blup	52	0.01	4.2e-02	10.7	10.3	4.5e-25	0.82	0.00	0.91	FALSE
34	The Cancer Genome Atlas	Colon Adenocarcinoma	MRPL43	0.07	0.02	blup	52	0.00	1.7e-01	10.3	-10.3	9.5e-25	-0.80	0.01	0.82	FALSE
11	GTEx	Breast Mammary Tissue (Male)	RP11-179B2.2	0.16	-0.01	enet	4	-0.01	7.1e-01	-10.0	10.2	1.8e-24	0.77	0.04	0.45	FALSE
21	GTEx	Skin Sun Exposed Lower leg	RP11-179B2.2	0.12	0.09	lasso	2	0.08	1.7e-07	10.1	9.9	2.5e-23	0.86	0.06	0.94	FALSE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SEMA4G	0.04	0.01	blup	52	0.02	1.2e-03	10.1	9.8	8.0e-23	0.83	0.01	0.80	FALSE
17	GTEx	Nerve Tibial	RP11-179B2.2	0.15	0.08	lasso	2	0.12	6.4e-09	10.7	9.8	8.8e-23	0.88	0.01	0.99	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	RP11-179B2.2	0.27	0.15	enet	36	0.15	2.0e-08	11.0	9.1	7.7e-20	0.75	0.00	1.00	FALSE
26	METSIM	Adipose	MRPL43	0.05	0.04	bslmm	422	0.04	1.9e-06	-7.1	9.1	9.5e-20	0.46	0.95	0.02	FALSE
54	The Cancer Genome Atlas	Thyroid Carcinoma	SEMA4G	0.07	0.08	blup	52	0.08	5.1e-08	-6.7	8.8	1.2e-18	0.75	0.04	0.96	FALSE
47	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	FAM178A	0.14	0.08	lasso	2	0.08	5.9e-04	-8.4	-8.5	2.1e-17	-0.53	0.07	0.13	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MRPL43	0.03	0.02	blup	52	0.03	3.0e-04	-6.7	-8.3	7.2e-17	-0.68	0.10	0.51	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	MRPL43	0.10	0.08	bslmm	411	0.09	1.2e-11	-7.0	-8.3	8.5e-17	-0.55	1.00	0.00	FALSE
50	The Cancer Genome Atlas	Stomach Adenocarcinoma	MRPL43	0.10	0.07	blup	51	0.09	3.3e-07	-7.0	-8.0	9.7e-16	-0.41	0.99	0.00	FALSE
14	GTEx	Heart Atrial Appendage	MRPL43	0.16	0.07	lasso	4	0.09	5.8e-05	-6.7	-7.9	2.7e-15	-0.62	0.39	0.15	FALSE
46	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MRPL43	0.06	0.04	blup	51	0.04	7.4e-04	-7.1	-7.9	4.0e-15	-0.52	0.55	0.08	FALSE
45	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MRPL43	0.05	0.05	enet	9	0.05	3.0e-03	-7.0	-7.7	1.4e-14	-0.44	0.12	0.07	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	MRPL43	0.02	0.02	enet	4	0.03	1.5e-06	-7.1	-7.5	4.5e-14	-0.51	0.98	0.00	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	LZTS2	0.02	0.03	lasso	2	0.02	3.6e-05	-6.7	7.0	1.8e-12	0.43	0.71	0.03	FALSE
52	The Cancer Genome Atlas	Thyroid Carcinoma	MRPL43	0.20	0.23	blup	52	0.26	8.0e-25	-7.1	-7.0	3.2e-12	-0.28	1.00	0.00	FALSE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	MRPL43	0.08	0.12	lasso	1	0.12	3.9e-13	-7.0	-7.0	3.4e-12	-0.41	1.00	0.00	FALSE
12	GTEx	Breast Mammary Tissue (Female)	RP11-179B2.2	0.19	0.00	lasso	3	-0.01	5.1e-01	9.9	6.7	2.3e-11	0.65	0.03	0.46	FALSE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MRPL43	0.02	0.02	blup	52	0.02	3.5e-03	-7.0	-6.7	2.4e-11	-0.36	0.09	0.04	FALSE
49	The Cancer Genome Atlas	Prostate Adenocarcinoma	MRPL43	0.13	0.16	lasso	10	0.15	2.4e-15	-7.0	-6.7	2.7e-11	-0.41	1.00	0.00	FALSE
48	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	MRPL43	0.27	0.24	enet	10	0.21	6.4e-09	-7.0	-6.4	1.4e-10	-0.35	1.00	0.00	FALSE
30	YFS	Blood	MRPL43	0.21	0.28	bslmm	415	0.28	1.1e-93	-7.0	-6.2	5.2e-10	-0.30	1.00	0.00	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	SEMA4G	0.04	0.02	enet	25	0.03	2.4e-04	-7.0	6.1	9.8e-10	0.58	0.21	0.70	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	HIF1AN	0.13	0.03	lasso	5	0.02	3.4e-02	-5.0	5.8	4.9e-09	0.03	0.26	0.03	FALSE
5	GTEx	Artery Tibial	MRPL43	0.13	0.05	lasso	3	0.06	1.8e-05	-7.7	-5.6	1.7e-08	-0.38	0.56	0.05	FALSE
43	The Cancer Genome Atlas	Brain Lower Grade Glioma	SEC31B	0.06	0.06	blup	51	0.06	1.1e-07	-5.0	5.6	2.0e-08	0.04	0.04	0.96	FALSE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	NDUFB8	0.02	0.01	blup	38	0.01	1.6e-02	-4.8	-5.5	2.8e-08	-0.05	0.02	0.61	FALSE
33	The Cancer Genome Atlas	Colon Adenocarcinoma	HIF1AN	0.07	0.03	blup	40	0.05	4.9e-04	-5.0	5.5	3.6e-08	0.05	0.03	0.83	FALSE
53	The Cancer Genome Atlas	Thyroid Carcinoma	SEC31B	0.12	0.19	blup	51	0.20	1.1e-18	-5.0	5.5	5.2e-08	0.06	0.05	0.95	FALSE
23	GTEx	Testis	HIF1AN	0.12	0.08	lasso	3	0.06	1.6e-03	-5.3	5.4	7.2e-08	0.07	0.34	0.04	FALSE
22	GTEx	Spleen	HIF1AN	0.19	0.19	lasso	3	0.12	6.8e-04	4.3	5.3	1.4e-07	0.01	0.13	0.05	FALSE
25	GTEx	Whole Blood	HIF1AN	0.15	0.12	enet	7	0.12	8.7e-11	-5.2	5.3	1.4e-07	0.06	1.00	0.00	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SEC31B	0.05	0.05	blup	51	0.05	8.9e-07	-4.9	5.2	2.0e-07	0.06	0.04	0.96	FALSE
2	GTEx	Adipose Visceral Omentum	SEC31B	0.18	0.28	lasso	10	0.27	1.5e-14	-5.0	5.2	2.1e-07	0.06	1.00	0.00	FALSE
20	GTEx	Skin Sun Exposed Lower leg	HIF1AN	0.07	0.05	lasso	8	0.03	2.2e-03	-5.1	5.2	2.1e-07	0.06	0.93	0.00	FALSE
35	The Cancer Genome Atlas	Colon Adenocarcinoma	SEC31B	0.06	0.07	blup	51	0.08	2.9e-05	-4.8	5.2	2.5e-07	0.06	0.04	0.95	FALSE
51	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SEC31B	0.24	0.20	blup	51	0.28	1.7e-10	-5.0	5.2	2.5e-07	0.06	0.04	0.96	FALSE
40	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SEC31B	0.14	0.10	lasso	7	0.10	1.6e-06	-5.2	5.2	2.6e-07	0.05	0.04	0.95	FALSE
6	GTEx	Artery Tibial	SEC31B	0.25	0.32	lasso	6	0.33	1.3e-26	-5.1	5.1	2.8e-07	0.07	1.00	0.00	FALSE