TWAS hub - HIF1AN

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1310	0.0340	4.9e-14	0.092	0.121	0.144	0.149	0.117	2.6e-11	1.4e-14	3.7e-17	8.8e-18	5.0e-14
2	GTEx	Artery Tibial	0.0676	0.0308	8.1e-03	0.006	NA	0.005	NA	0.007	9.7e-02	NA	1.3e-01	NA	8.2e-02
3	GTEx	Esophagus Gastroesophageal Junction	0.1470	0.0580	1.6e-03	0.037	NA	0.090	NA	0.065	1.8e-02	NA	3.7e-04	NA	2.2e-03
4	GTEx	Esophagus Mucosa	0.1430	0.0460	4.0e-06	0.081	NA	0.081	NA	0.086	4.3e-06	NA	4.4e-06	NA	2.2e-06
5	GTEx	Esophagus Muscularis	0.1090	0.0470	1.0e-03	0.101	NA	0.113	NA	0.091	1.0e-06	NA	2.3e-07	NA	3.6e-06
6	GTEx	Muscle Skeletal	0.0456	0.0211	3.6e-03	0.057	NA	0.039	NA	0.048	3.0e-06	NA	1.0e-04	NA	1.6e-05
7	GTEx	Skin Not Sun Exposed Suprapubic	0.1330	0.0580	1.6e-03	0.029	NA	0.007	NA	0.018	1.0e-02	NA	1.3e-01	NA	3.3e-02
8	GTEx	Skin Sun Exposed Lower leg	0.0730	0.0300	6.5e-04	0.046	NA	0.023	NA	0.028	1.0e-04	NA	4.8e-03	NA	2.2e-03
9	GTEx	Spleen	0.1920	0.0770	4.4e-03	0.188	NA	0.103	NA	0.116	1.5e-05	NA	1.4e-03	NA	6.7e-04
10	GTEx	Testis	0.1220	0.0490	1.1e-03	0.080	NA	0.010	NA	0.057	2.0e-04	NA	1.1e-01	NA	1.6e-03
11	GTEx	Whole Blood	0.1490	0.0400	2.5e-11	0.118	NA	0.116	NA	0.112	5.1e-11	NA	8.8e-11	NA	1.9e-10
12	METSIM	Adipose	0.0619	0.0207	4.3e-05	0.030	0.025	0.030	0.032	0.040	1.9e-05	9.2e-05	2.4e-05	1.2e-05	1.1e-06
13	NTR	Blood	0.0234	0.0081	1.2e-06	0.025	0.019	0.019	0.019	0.021	9.8e-09	7.7e-07	7.1e-07	5.5e-07	1.4e-07
14	ROSMAP	Brain Pre-frontal Cortex	0.0790	0.0302	1.7e-04	0.056	0.039	0.044	0.045	0.038	8.7e-08	7.1e-06	1.9e-06	1.8e-06	1.0e-05
15	YFS	Blood	0.0572	0.0141	0.0e+00	0.061	0.060	0.069	0.068	0.071	2.7e-19	4.6e-19	9.8e-22	3.1e-21	2.5e-22
16	TCGA	Colon Adenocarcinoma	0.0680	0.0550	7.7e-04	0.035	0.053	0.041	NA	0.039	4.3e-03	4.9e-04	2.1e-03	NA	2.6e-03
17	TCGA	Brain Lower Grade Glioma	0.1836	0.0838	1.2e-04	0.001	0.037	0.040	NA	0.011	2.3e-01	4.1e-05	2.3e-05	NA	1.6e-02
18	TCGA	Pheochromocytoma and Paraganglioma	0.1860	0.1170	1.6e-03	-0.006	0.056	0.034	NA	0.014	6.3e-01	2.9e-03	1.7e-02	NA	8.7e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Birth weight	6.5	14.2	26.7	-3.8	-3.3	-4.7	4.0	-5.2	-4.1	3.7	4.3	2.0	4.2	4.2	-1.7	4.1	2.3	3.8	3.8	-2.5	-4.1
Pulse rate, automated reading	6.1	19.8	31.5	-4.5	-2.8	-3.7	5.1	-3.9	-5.5	4.3	5.5	2.7	5.1	5.3	-0.3	5.6	1.9	5.0	5.0	-4.0	-5.6
Medication: Metformin	5.4	7.6	12.5	-2.4	-0.8	-2.0	3.5	-2.6	-3.3	3.3	3.3	2.5	3.4	3.4	0.2	3.3	0.9	3.0	3.5	-1.6	-3.0
Diabetes (self-reported)	5.4	8.3	14.3	-2.0	-0.5	-1.1	3.7	-2.8	-3.4	3.8	3.3	3.5	3.3	3.4	1.4	3.4	2.0	3.6	3.8	0.2	-2.6
Leg fat-free mass (left)	5.3	28.2	45.0	-4.6	-2.4	-4.0	6.6	-5.2	-6.6	6.5	6.6	4.4	6.7	6.7	0.1	6.6	0.0	5.9	6.6	-1.5	-5.6
Leg predicted mass (left)	5.3	28.2	45.1	-4.6	-2.4	-3.9	6.6	-5.2	-6.6	6.5	6.6	4.4	6.7	6.7	0.1	6.6	0.0	5.9	6.6	-1.5	-5.6
Leg fat-free mass (right)	5.2	28.0	44.8	-4.5	-2.1	-3.8	6.6	-5.2	-6.6	6.6	6.5	4.5	6.7	6.7	0.4	6.6	0.3	6.0	6.6	-1.3	-5.5
Leg predicted mass (right)	5.1	27.2	43.5	-4.5	-2.0	-3.7	6.5	-5.1	-6.5	6.5	6.5	4.5	6.6	6.6	0.4	6.5	0.1	5.9	6.5	-1.4	-5.4
Diabetes (father)	5.0	6.2	12.6	-2.0	0.1	-0.5	2.9	-1.2	-3.0	3.5	3.0	3.2	3.1	3.0	1.5	3.0	1.8	2.9	3.4	0.3	-2.1
Chronic bronchitis/emphysema (father)	4.7	5.6	7.9	2.8	1.9	2.3	-2.4	2.5	2.7	-2.0	-2.7	-1.6	-2.8	-2.7	0.6	-2.8	-1.3	-2.4	-2.5	2.3	2.8
Whole body fat-free mass	4.2	24.0	40.1	-4.0	-1.6	-2.9	6.1	-4.6	-6.1	6.3	6.1	4.5	6.3	6.2	0.8	6.1	-0.3	5.6	6.2	-1.4	-5.1
Basal metabolic rate	4.2	23.4	38.5	-4.1	-1.7	-3.1	6.0	-4.6	-6.0	6.1	6.0	4.2	6.2	6.1	0.5	6.1	-0.2	5.3	6.1	-1.3	-5.1
Whole body water mass	4.1	23.6	39.1	-4.0	-1.6	-2.9	6.0	-4.5	-6.0	6.2	6.0	4.4	6.2	6.1	0.7	6.1	-0.4	5.5	6.1	-1.4	-5.1
Type 2 Diabetes (T2D) (2018)	4.0	7.4	13.9	-2.0	-0.8	-1.0	3.7	-2.5	-3.3	3.6	3.2	2.8	3.2	3.2	0.6	3.3	1.7	3.3	3.6	0.7	-2.7
Hearing difficulty/problems: Yes	3.8	5.7	9.8	-1.8	-0.3	-1.6	2.7	-2.0	-3.0	2.9	3.1	2.0	3.0	3.1	0.4	3.0	1.5	2.8	3.0	-0.5	-2.8
Arm fat-free mass (right)	3.7	18.9	33.4	-3.5	-0.9	-2.0	5.4	-3.8	-5.4	5.8	5.3	4.3	5.7	5.5	1.3	5.4	-0.2	4.9	5.6	-0.9	-4.4
Sitting height	3.6	25.5	39.8	-4.0	-3.1	-4.2	5.7	-4.8	-6.1	6.2	6.2	5.0	6.1	6.3	0.2	6.2	2.1	6.2	6.3	-1.0	-4.9
Neck or shoulder pain in last month	3.6	5.1	9.0	-2.6	-2.0	-3.0	2.6	-1.7	-2.7	1.7	2.7	0.6	2.4	2.5	-1.6	2.8	1.0	2.2	2.1	-2.1	-3.0
Arm predicted mass (left)	3.6	18.1	31.4	-3.6	-1.1	-2.2	5.4	-4.0	-5.3	5.4	5.3	3.8	5.6	5.4	0.7	5.4	-0.6	4.5	5.3	-1.3	-4.6
Trunk fat-free mass	3.5	20.1	35.9	-3.4	-1.3	-2.3	5.5	-4.1	-5.5	6.0	5.6	4.5	5.8	5.6	1.0	5.6	-0.5	5.2	5.7	-1.1	-4.5
Trunk predicted mass	3.5	20.1	35.4	-3.5	-1.4	-2.4	5.5	-4.2	-5.5	6.0	5.6	4.4	5.8	5.7	0.8	5.6	-0.6	5.2	5.7	-1.2	-4.6
Arm predicted mass (right)	3.5	17.9	30.7	-3.4	-0.9	-2.0	5.3	-3.8	-5.3	5.5	5.2	4.0	5.5	5.4	1.1	5.3	-0.2	4.7	5.4	-1.1	-4.5
Forced expiratory volume in 1-second (FEV1), predicted	3.5	7.3	13.4	-2.0	-1.7	-1.7	3.2	-2.7	-3.1	3.7	3.3	3.0	3.4	3.3	0.5	3.1	1.0	3.3	3.5	0.1	-2.2
Diabetes diagnosed by doctor	3.5	5.7	10.6	-1.7	-0.3	-0.6	3.3	-2.3	-2.8	3.1	2.8	2.9	2.8	2.8	1.0	2.8	1.1	3.0	3.1	0.2	-2.2
Arm fat-free mass (left)	3.5	18.0	30.9	-3.5	-1.1	-2.2	5.3	-3.9	-5.3	5.5	5.3	3.8	5.6	5.4	0.7	5.4	-0.5	4.6	5.4	-1.2	-4.6
Impedance of leg (left)	3.4	16.6	27.1	3.6	2.0	3.4	-4.9	3.9	4.9	-5.0	-5.1	-3.6	-5.2	-5.0	0.0	-4.9	0.2	-4.9	-5.1	1.4	4.1
Weight	3.4	16.5	27.5	-3.7	-1.6	-3.1	5.2	-4.0	-5.2	4.7	5.0	2.8	5.2	5.2	-0.5	5.2	0.3	4.1	5.0	-0.9	-4.6
Taking other prescription medications	3.3	5.1	11.9	2.8	2.3	3.0	-1.9	3.5	2.5	-1.8	-2.5	-0.9	-2.5	-2.4	1.1	-2.5	-0.8	-2.0	-2.2	1.9	2.4
Birth weight of first child	3.3	6.0	10.0	-2.1	-1.3	-1.8	2.9	-2.1	-3.0	3.1	2.9	2.5	2.8	2.9	0.2	3.0	1.4	2.9	3.2	-0.8	-2.3
Comparative height size at age 10	3.3	18.0	35.2	-2.3	-0.9	-1.9	5.0	-2.7	-5.0	5.8	5.2	5.3	5.4	5.3	1.7	5.1	1.6	5.9	5.5	0.2	-3.6
Average weekly beer plus cider intake	3.2	4.6	7.3	1.5	0.9	2.5	-1.8	2.3	2.5	-2.4	-2.7	-1.6	-2.4	-2.5	0.4	-2.6	-1.0	-2.7	-2.4	2.1	2.5
Hearing aid user	3.1	3.5	7.2	-1.0	-0.3	-1.4	2.1	-1.0	-2.0	2.6	2.0	2.4	2.2	2.2	0.7	2.0	2.7	2.1	2.3	-0.3	-1.4
Number of incorrect matches in round	3.0	5.1	8.6	1.9	1.1	2.2	-2.4	1.8	2.5	-2.6	-2.5	-2.4	-2.4	-2.6	-0.2	-2.6	-2.9	-2.7	-2.9	0.9	1.8
Hand grip strength (right)	2.8	7.6	12.0	-2.7	-0.7	-2.0	2.9	-3.5	-3.4	3.0	3.4	2.2	3.4	3.4	0.7	3.4	0.4	3.1	3.2	-1.6	-3.0
Hand grip strength (left)	2.7	7.1	11.3	-2.9	-1.3	-2.4	2.9	-3.2	-3.2	2.6	3.2	1.3	3.3	3.4	-0.3	3.2	1.1	2.3	2.8	-2.1	-3.4
Maternal smoking around birth	2.7	4.0	14.7	2.1	3.1	3.8	-1.4	2.5	1.7	-1.5	-1.7	-0.6	-1.8	-1.7	2.2	-1.7	-1.5	-1.0	-1.4	1.7	2.0
Peak expiratory flow (PEF)	2.7	6.3	10.9	-1.6	-0.6	-2.4	2.7	-2.1	-3.0	3.0	3.0	2.7	3.0	3.1	0.6	3.0	2.5	3.3	3.2	-0.6	-2.2
Fractured/broken bones in last 5 years	2.7	3.5	5.9	-1.5	-1.6	-1.8	2.1	-1.4	-2.0	2.3	2.4	1.1	2.3	2.1	-1.0	2.0	0.4	2.3	2.0	-1.8	-2.0
Ever had prostate specific antigen (PSA) test	2.6	3.0	8.5	1.2	-0.2	0.9	-1.9	0.7	1.9	-2.4	-1.8	-2.9	-2.0	-2.0	-1.2	-1.9	-1.5	-2.3	-2.3	-0.4	0.9
Impedance of leg (right)	2.5	12.0	19.7	3.0	1.1	2.7	-4.3	3.3	4.1	-4.3	-4.4	-3.1	-4.4	-4.2	-0.4	-4.1	0.1	-4.3	-4.3	1.1	3.5
Hip circumference	2.5	10.8	17.2	-3.1	-2.0	-3.3	4.1	-3.0	-4.1	3.6	4.1	1.7	4.1	4.1	-1.4	4.1	1.2	3.0	3.9	-1.0	-3.9
Standing height	2.5	24.4	39.2	-3.9	-2.6	-3.0	6.0	-4.7	-6.1	6.2	6.1	4.7	6.1	6.3	0.5	6.2	1.3	5.8	6.2	-0.9	-5.0
Illnesses of father: None of the above (group 1)	2.5	3.1	6.0	2.3	2.2	2.1	-2.1	1.4	1.9	-1.1	-1.9	0.5	-1.9	-1.9	2.0	-1.9	0.3	-0.6	-1.4	1.9	2.4
Happiness	2.4	2.9	5.9	-2.2	-2.0	-2.4	2.1	-0.5	-1.9	1.3	1.9	0.2	2.0	2.0	-2.0	1.8	0.3	1.0	1.6	-0.5	-2.1
Forced expiratory volume in 1-second (FEV1)	2.3	7.9	13.6	-2.0	-0.6	-2.2	2.8	-2.2	-3.4	3.7	3.5	3.0	3.4	3.5	0.6	3.4	2.0	3.7	3.7	-1.3	-2.6
Back pain experienced in last month	2.3	3.4	8.7	1.6	1.3	2.1	-1.9	3.0	1.9	-1.6	-2.0	-1.6	-1.7	-2.0	0.3	-1.9	-1.9	-2.0	-1.9	1.4	1.8
Medication: Atorvastatin	2.3	2.9	10.7	1.0	1.1	2.2	-1.3	1.0	1.8	-2.0	-1.6	-1.7	-1.7	-1.8	0.0	-1.8	-3.3	-2.1	-1.9	-0.3	1.2
Irritability	2.3	3.9	6.2	-2.0	-1.7	-2.1	2.2	-2.4	-2.4	2.0	2.3	1.3	2.5	2.3	-0.7	2.4	-0.1	1.8	2.2	-1.1	-2.1
Heel T-Score	2.2	17.8	32.9	4.1	3.4	3.1	-5.0	3.1	5.3	-5.7	-5.0	-3.6	-5.2	-5.1	0.7	-5.2	0.6	-4.3	-5.4	1.7	4.3
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	4.1	-1.4	-0.1	-0.6	2.0	-1.5	-1.9	1.8	1.8	1.6	1.9	1.8	0.7	1.9	0.7	1.9	2.0	-1.2	-1.6
Relative age voice broke	2.2	3.3	9.8	0.0	-0.6	0.2	-1.3	-0.0	1.9	-3.0	-1.6	-3.1	-2.0	-1.8	-2.1	-1.9	-1.7	-2.3	-2.5	-1.4	0.5
Qualifications: A levels/AS levels or equivalent	2.2	4.8	14.8	-0.7	-0.1	-1.3	1.7	-1.8	-2.2	2.6	2.3	3.9	2.1	2.1	2.0	2.2	2.9	3.3	2.8	1.0	-0.8
Mean Putamen Volume	2.1	2.4	4.3	-1.2	-0.8	-1.8	1.6	-2.1	-1.7	1.4	1.7	1.0	1.6	1.7	-0.9	1.7	1.3	1.5	1.6	-1.8	-1.7
Headache pain in last month	2.1	3.5	10.4	-1.8	-2.8	-3.2	1.9	-1.0	-1.8	1.5	1.9	0.4	1.9	1.9	-1.8	1.8	1.8	1.3	1.6	-1.8	-2.0
Health satisfaction	2.1	2.7	5.2	-1.9	-0.1	-1.9	2.0	-0.8	-2.1	1.3	2.0	0.6	2.2	2.1	-1.1	2.1	0.1	1.3	1.8	-0.9	-2.3
Commuting to job workplace: Walk	2.1	2.3	5.2	-1.8	-1.2	-1.9	1.6	-1.8	-1.5	0.9	1.8	0.1	1.4	1.6	-1.2	1.5	-0.2	1.6	1.1	-1.8	-2.3
Crohns Disease (2012)	2.0	3.3	9.7	2.5	3.1	2.6	-1.3	2.6	1.4	-1.1	-1.6	0.0	-1.8	-1.5	1.9	-1.4	1.1	-0.9	-1.1	2.0	1.7
LDL Cholesterol	2.0	3.1	6.2	1.3	0.2	0.6	-2.4	1.2	2.0	-2.3	-2.0	-2.4	-2.1	-2.1	-0.7	-2.0	-1.4	-2.5	-2.3	0.3	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.3	13.1	-1.5	-0.1	-1.5	2.4	-1.7	-2.8	3.6	3.0	3.2	3.0	3.0	0.9	2.9	2.1	3.6	3.3	-0.7	-1.9
Friendships satisfaction	2.0	2.5	6.8	-1.7	-2.6	-2.4	1.7	-0.9	-1.8	1.2	1.6	0.3	1.6	1.7	-1.5	1.8	0.5	0.9	1.5	-1.3	-1.7
Arm fat mass (left)	2.0	8.3	14.7	-2.8	-1.2	-2.6	3.8	-2.9	-3.7	3.0	3.5	1.5	3.7	3.6	-0.8	3.7	0.2	2.5	3.5	-0.9	-3.4
Diastolic blood pressure, automated reading	2.0	6.2	14.6	-3.8	-3.3	-2.9	2.4	-2.9	-2.8	1.6	2.5	0.0	2.5	2.7	-1.9	2.9	-1.1	1.1	2.2	-2.3	-3.0
Arm fat mass (right)	1.9	7.7	13.0	-2.7	-1.3	-2.7	3.6	-2.9	-3.5	2.8	3.4	1.2	3.6	3.5	-1.1	3.6	0.2	2.3	3.3	-1.0	-3.3
Chronic bronchitis/emphysema (mother)	1.9	2.3	3.6	1.6	-0.3	1.0	-1.5	1.6	1.8	-1.5	-1.7	-1.2	-1.9	-1.8	-0.8	-1.9	-0.2	-1.4	-1.7	1.8	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	6.7	1.9	2.0	2.6	-0.6	1.6	0.9	0.7	-1.0	1.2	-0.9	-0.8	2.5	-0.9	0.8	-0.4	-0.0	2.5	1.9
Trunk fat mass	1.8	7.5	14.5	-2.6	-1.2	-2.3	3.8	-2.7	-3.5	2.9	3.3	1.4	3.5	3.5	-0.8	3.5	0.7	2.4	3.3	-0.6	-3.2
Forced vital capacity (FVC)	1.8	7.1	12.1	-1.9	-1.2	-2.1	2.8	-2.3	-3.2	3.5	3.3	2.7	3.2	3.3	0.2	3.3	1.2	3.3	3.4	-1.3	-2.6
Mouth/teeth dental problems: Dentures	1.8	3.0	5.2	-2.3	-1.0	-1.8	1.8	-1.1	-1.9	1.6	2.2	0.7	1.7	1.9	-0.9	1.9	1.9	1.8	1.6	-2.2	-2.3
Forced vital capacity (FVC), Best measure	1.8	6.4	13.1	-1.8	-0.9	-1.7	2.6	-1.9	-3.0	3.6	3.1	2.9	3.1	3.2	0.3	3.0	1.4	3.4	3.3	-0.8	-2.2
Height	1.7	32.0	53.3	-4.9	-3.4	-3.2	7.2	-4.6	-7.1	6.9	7.0	5.0	7.3	7.2	-0.2	7.1	1.0	6.4	7.1	-1.4	-6.0
Number of live births	1.7	2.4	3.5	1.6	0.5	1.8	-1.8	1.2	1.9	-1.6	-1.7	-1.3	-1.9	-1.8	0.1	-1.8	-1.5	-1.6	-1.7	0.7	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.6	5.5	2.4	1.8	1.1	-1.6	1.8	1.8	-1.1	-2.0	-0.6	-1.8	-1.8	0.7	-1.8	0.2	-1.8	-1.5	1.7	1.9
Impedance of whole body	1.7	8.8	15.3	2.5	0.6	1.8	-3.6	2.8	3.6	-3.9	-3.7	-2.8	-3.9	-3.7	-0.5	-3.6	1.0	-3.4	-3.7	1.1	3.0
Serious illness, injury or assault to yourself	1.6	1.9	4.2	-0.9	0.6	0.0	1.5	0.2	-1.6	2.1	1.7	1.8	1.7	1.6	0.8	1.6	1.0	2.0	1.8	-0.7	-1.2
Whole body fat mass	1.6	6.7	12.7	-2.6	-1.1	-2.2	3.6	-2.8	-3.4	2.6	3.1	1.1	3.3	3.3	-0.8	3.4	0.2	2.1	3.1	-0.6	-3.1
Schizophrenia (2018)	1.5	3.1	12.3	-1.5	-2.3	-1.9	-0.4	0.4	0.3	-1.6	0.0	-3.1	-0.2	-0.3	-3.5	-0.3	-2.6	-1.3	-1.4	-2.7	-1.4
Verbal and Numeric Reasoning (VNR)	1.5	3.5	9.6	-0.8	-1.6	-3.1	1.9	-2.2	-1.9	1.8	1.9	2.2	1.8	1.9	-0.6	1.9	1.9	2.1	2.3	0.6	-1.1
Hypothyroidism (self reported)	1.5	3.5	5.8	-2.0	-1.7	-2.0	2.4	-1.7	-2.2	1.8	2.2	1.0	2.0	2.2	-0.9	2.2	1.3	2.0	1.9	-1.4	-2.1
Vitamin and mineral supplements	1.5	2.1	8.0	-2.2	-2.0	-1.4	-0.0	-0.1	-0.7	-0.5	0.7	-1.9	0.7	0.6	-2.3	0.7	-1.8	-0.5	-0.0	-2.8	-1.8
Medication: Lansoprazole	1.5	1.7	5.1	1.4	1.7	1.3	-1.0	1.3	1.3	-1.0	-1.4	-0.2	-1.4	-1.3	0.6	-1.3	-0.4	-0.9	-1.0	2.3	1.8
Length of working week for main job	1.5	1.7	3.8	-1.3	-1.4	-1.9	1.3	-1.6	-1.4	0.6	1.3	-0.3	1.0	1.2	-1.5	1.4	0.4	0.9	0.9	-1.8	-1.7
Breastfed as a baby	1.5	1.8	8.2	-1.5	-2.7	-2.1	0.4	-0.9	-0.4	-0.0	0.6	-1.5	0.4	0.5	-2.9	0.4	-0.9	-0.2	0.0	-2.0	-1.3
Tense / ‘highly strung’	1.5	2.6	4.2	1.6	0.8	1.5	-1.1	1.3	1.8	-1.7	-2.0	-0.9	-1.7	-2.0	-0.1	-1.8	-1.9	-2.0	-1.7	1.3	2.0
Supplements: Zinc	1.4	1.6	4.6	-1.5	-0.4	-0.5	2.1	-1.2	-1.6	0.9	1.4	0.8	1.5	1.6	0.0	1.5	0.0	1.4	1.3	-0.7	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	3.3	-1.0	-0.7	-1.7	1.2	-1.2	-1.8	1.8	1.4	1.1	1.6	1.6	-0.6	1.7	1.0	1.2	1.7	-0.0	-1.4
Medication: Ramipril	1.4	1.7	4.6	-0.1	1.4	0.7	1.1	-0.6	-1.2	1.9	1.3	2.2	1.2	1.1	2.0	1.3	0.5	1.8	1.7	0.9	-0.6
Time employed in main current job	1.4	1.6	3.3	-1.2	-1.5	-1.8	1.1	-1.7	-1.3	1.3	1.4	0.2	1.2	1.3	-1.2	1.3	0.7	0.6	1.2	-1.5	-1.3
Worry too long after embarrassment	1.4	2.4	5.5	2.1	1.2	0.8	-1.6	0.8	1.8	-1.4	-1.8	-0.3	-1.7	-1.8	0.2	-1.9	-1.0	-1.2	-1.6	2.3	2.1
Illnesses of father: Heart disease	1.4	2.0	7.2	-1.7	-1.6	-1.6	0.8	-1.1	-0.9	-0.4	0.9	-1.7	0.7	0.8	-2.4	1.0	-1.6	-0.3	0.2	-2.7	-2.0
Pack years of smoking	1.4	2.1	6.6	0.6	0.5	1.1	-1.2	1.5	1.3	-2.1	-1.2	-2.4	-1.4	-1.3	-1.1	-1.3	-2.6	-1.5	-1.8	-0.5	0.5
Schizophrenia (2014)	1.3	2.8	10.7	-1.2	-2.5	-1.9	-0.4	0.7	0.3	-1.6	-0.1	-2.9	-0.3	-0.3	-3.3	-0.3	-2.3	-1.4	-1.3	-2.4	-1.2
Type 2 Diabetes (T2D) (2012)	1.3	1.5	4.9	-1.3	-0.6	-0.3	2.2	-0.9	-1.4	1.2	1.5	0.2	1.7	1.5	-0.1	1.3	0.4	1.1	1.3	-1.0	-1.4
Relative age of first facial hair	1.3	2.7	6.3	0.6	-0.4	0.5	-1.5	0.9	1.8	-2.5	-1.9	-2.5	-2.0	-2.0	-1.4	-1.8	0.0	-2.3	-2.2	-1.1	1.0
Multivitamins +/- minerals	1.3	1.6	6.1	2.0	1.7	1.2	-0.5	-0.2	0.7	0.1	-0.7	1.8	-0.8	-0.7	2.5	-0.7	1.3	0.4	-0.1	2.0	1.8
Waist circumference	1.3	4.6	8.5	-1.8	0.5	-0.9	2.9	-1.7	-2.8	2.8	2.6	1.6	2.8	2.8	0.5	2.8	0.9	2.1	2.9	0.2	-2.2
Leg fat mass (right)	1.3	5.2	9.3	-2.3	-0.8	-1.9	3.0	-2.5	-2.9	2.4	2.7	1.1	3.0	2.9	-0.7	3.0	-0.2	1.8	2.8	-0.5	-2.7
Smoking status: Previous	1.3	2.0	6.1	0.3	0.7	-0.1	1.2	-0.9	-1.2	1.8	1.0	2.5	0.8	1.0	1.8	1.1	2.5	1.9	1.7	1.6	-0.0
Pain experienced in last month	1.3	2.1	7.2	1.7	1.8	2.7	-1.6	0.0	1.4	-0.4	-1.2	0.9	-1.2	-1.2	2.1	-1.3	-1.4	-0.2	-0.7	1.5	1.8
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	3.1	-1.8	-1.2	-1.4	1.7	-1.4	-1.5	0.9	1.5	0.1	1.5	1.5	-1.0	1.5	-0.6	1.1	1.2	-0.9	-1.6
Pack years adult smoking proportion	1.2	1.8	6.7	0.4	0.6	0.9	-1.2	1.6	1.1	-1.9	-1.0	-2.2	-1.2	-1.1	-0.9	-1.1	-2.6	-1.3	-1.6	-0.6	0.2
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	3.6	-1.2	-0.9	-1.6	1.9	-1.5	-1.8	1.9	1.4	1.1	1.6	1.6	-0.3	1.7	0.2	1.0	1.8	-0.3	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.8	1.3	-0.2	0.3	-1.4	0.5	1.4	-0.7	-1.5	-0.4	-1.2	-1.4	-0.6	-1.4	0.7	-1.4	-1.0	2.2	1.4
Medication: Allopurinol	1.2	1.6	4.1	0.7	1.8	2.0	-0.6	1.3	1.2	-1.5	-1.1	-1.3	-1.3	-1.2	1.1	-1.2	-1.2	-1.3	-1.5	-0.9	0.5
Number of full sisters	1.2	1.5	4.9	-1.3	-0.3	-1.1	1.5	-1.8	-1.2	0.5	1.2	-0.6	1.0	1.3	-0.8	1.2	0.5	0.4	0.8	-2.2	-1.7
Risk taking	1.2	1.8	3.3	1.0	1.4	1.8	-1.2	1.6	1.5	-1.2	-1.5	-1.1	-1.4	-1.5	0.7	-1.5	-1.3	-1.3	-1.5	0.7	1.2
Intelligence (Savage-Jansen 2018)	1.1	3.3	7.0	-1.1	-1.9	-2.6	2.0	-1.7	-2.0	1.5	2.0	1.8	1.9	2.1	-0.8	2.0	1.8	2.3	2.2	-0.1	-1.4
Bipolar Disorder (2011)	1.1	1.1	2.6	-0.4	-0.4	-0.9	1.0	0.1	-1.1	1.4	1.2	1.2	1.0	1.1	0.5	1.1	1.6	1.6	1.3	-0.2	-0.8
Blood White Count	1.1	8.3	13.1	3.3	2.7	3.1	-3.1	3.6	3.2	-2.6	-3.2	-1.5	-3.2	-3.1	1.4	-3.2	-2.0	-3.0	-2.9	2.5	3.1
BMI	1.1	6.4	11.7	-1.9	0.4	-1.2	3.3	-1.8	-3.4	3.0	3.1	2.4	3.3	3.3	1.1	3.4	0.5	2.7	3.4	0.5	-2.6
Pulse rate	1.1	1.9	3.6	-1.7	-1.5	-1.3	1.4	-0.8	-1.7	1.0	1.7	0.2	1.3	1.5	-1.0	1.8	-0.1	1.5	1.3	-1.6	-1.9
Prospective memory result	1.1	1.4	2.1	1.0	0.8	1.5	-1.3	0.7	1.3	-1.2	-1.3	-1.4	-1.3	-1.3	-0.4	-1.3	-1.3	-1.4	-1.4	0.3	1.2
Exposure to tobacco smoke at home	1.1	1.3	3.2	0.2	0.1	-0.1	-1.2	0.3	1.1	-1.6	-1.4	-1.7	-1.3	-1.2	-1.1	-1.1	-0.5	-1.8	-1.5	0.6	0.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	5.6	1.7	1.2	0.1	-1.1	0.7	1.1	-0.4	-1.4	0.4	-1.4	-1.1	0.5	-1.1	0.6	-0.8	-0.8	2.4	1.9
Gout (self-reported)	1.1	1.5	4.6	0.8	1.6	2.1	-0.8	0.5	1.2	-1.5	-1.2	-1.1	-1.3	-1.2	1.6	-1.3	-0.9	-1.4	-1.5	-0.5	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	4.8	-0.2	0.3	0.7	-0.8	1.1	1.0	-1.8	-1.0	-2.2	-1.1	-0.9	-0.9	-1.0	-1.7	-1.6	-1.5	-0.5	0.0
Wears glasses or contact lenses	1.1	1.2	2.3	1.2	0.3	0.9	-0.9	1.0	1.3	-1.3	-1.3	-0.8	-1.4	-1.3	-0.5	-1.3	-1.0	-1.5	-1.2	0.7	1.4
Medication: Paracetamol	1.1	1.7	6.2	-0.2	-0.5	-0.1	-1.0	0.6	1.2	-1.8	-1.2	-2.5	-1.1	-1.2	-1.6	-1.2	-1.2	-2.2	-1.6	-0.4	0.5
Supplements: Calcium	1.1	1.2	6.0	1.8	1.0	1.3	-0.5	0.7	0.9	0.4	-0.9	1.0	-0.7	-0.7	0.5	-0.9	0.9	-0.3	-0.3	2.5	1.7
Leg fat mass (left)	1.1	4.5	8.3	-2.1	-0.5	-1.7	2.9	-2.3	-2.8	2.3	2.5	1.0	2.8	2.7	-0.6	2.8	-0.2	1.6	2.6	-0.4	-2.5
Ulcerative Colitis	1.0	1.5	3.0	1.6	1.3	1.4	-0.9	1.4	1.2	-0.4	-1.4	-0.3	-1.6	-1.1	1.2	-1.2	0.3	-1.1	-0.9	1.7	1.6
Blood clot in the leg (DVT)	1.0	1.3	2.3	-1.4	-1.0	-1.3	1.5	-1.3	-1.2	0.8	1.3	0.1	1.2	1.2	-1.0	1.2	-0.7	1.0	0.9	-0.9	-1.4
Number of full brothers	1.0	1.3	2.4	-1.1	-0.3	-1.2	1.4	-0.6	-1.4	1.0	1.2	0.7	1.3	1.4	-0.0	1.4	1.1	1.2	1.2	-1.2	-1.5
Had major operations	1.0	1.2	2.6	-0.6	-0.6	-0.8	1.5	-1.6	-1.3	1.1	1.2	1.2	1.0	1.2	-0.1	1.3	1.3	1.2	1.4	0.2	-0.9
Commuting to job workplace: Public transport	1.0	1.1	2.8	-0.4	-1.3	-1.6	0.7	-1.3	-1.1	1.1	1.3	0.7	0.8	1.1	-0.8	1.1	0.7	1.7	1.2	0.5	-0.7
Medication: Lisinopril	1.0	1.3	2.8	1.1	0.6	1.6	-0.7	0.8	1.0	-0.9	-1.2	-0.6	-1.3	-1.3	0.7	-1.0	-1.7	-1.2	-0.9	1.4	1.3
Myopia	1.0	1.4	4.5	-0.2	-1.5	-0.8	-1.1	0.8	0.7	-1.6	-0.8	-2.1	-0.8	-0.8	-2.0	-0.7	-1.7	-1.3	-1.3	-0.6	-0.1
Primary Biliary Cirrhosis	0.9	1.3	2.6	0.8	1.4	1.6	-0.8	0.5	1.3	-1.3	-1.4	-1.2	-1.3	-1.2	0.3	-1.3	-0.9	-1.5	-1.5	0.6	0.8
Waist Hip Ratio (WHR)	0.9	4.0	14.5	1.9	3.8	3.7	-1.3	1.8	1.6	-0.7	-1.8	0.2	-1.7	-1.7	3.4	-1.5	-0.1	-1.1	-1.1	1.8	2.1
Sensitivity / hurt feelings	0.9	1.5	6.4	1.2	2.5	2.1	-0.8	0.9	0.9	-0.7	-1.1	-0.3	-1.1	-1.1	1.5	-0.9	-0.5	-0.8	-0.9	1.3	1.1
Severe depression (siblings)	0.9	1.0	2.3	0.8	-0.1	0.5	-1.2	0.7	1.1	-1.5	-1.2	-0.9	-1.4	-1.2	-0.2	-1.1	-1.3	-1.0	-1.3	0.1	0.8
Body mass index (BMI)	0.9	3.9	7.1	-2.0	-0.4	-1.7	2.7	-2.0	-2.6	2.0	2.4	0.7	2.6	2.5	-0.7	2.6	-0.4	1.5	2.4	-0.5	-2.4
Financial difficulties in last 2 years	0.9	1.2	5.1	1.2	2.3	2.0	-0.6	0.8	0.7	-0.1	-0.7	-0.2	-0.6	-0.8	1.3	-0.7	-1.5	-0.3	-0.6	1.2	0.8
Arm fat percentage (right)	0.9	3.7	6.7	-2.2	-1.5	-2.6	2.4	-2.1	-2.3	1.2	2.1	-0.3	2.2	2.2	-2.0	2.3	0.1	1.0	1.9	-1.2	-2.5
Depression (self-reported)	0.9	1.1	2.3	1.2	1.1	0.3	-1.4	1.5	1.1	-0.6	-1.2	-0.9	-1.1	-1.1	-0.1	-1.2	-0.8	-1.4	-1.0	0.7	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	2.4	1.5	0.9	0.7	-1.5	1.3	1.3	-0.7	-1.3	-0.2	-1.2	-1.2	0.4	-1.3	-0.3	-1.1	-1.0	0.8	1.3
Commuting to job workplace: Car/motor vehicle	0.9	1.0	3.6	1.0	1.6	1.9	-0.7	1.2	0.9	-0.6	-1.0	-0.2	-0.8	-1.0	0.9	-1.0	0.6	-0.9	-0.8	0.6	0.9
Arm fat percentage (left)	0.9	3.7	6.4	-2.1	-1.4	-2.5	2.5	-2.1	-2.4	1.5	2.2	0.1	2.3	2.3	-1.6	2.4	0.4	1.2	2.1	-0.9	-2.4
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	1.7	1.0	0.7	1.1	-1.2	0.1	0.9	-1.1	-1.2	-0.6	-1.0	-0.9	0.6	-0.9	-0.9	-1.3	-0.9	0.9	1.0
Medication: Gliclazide	0.9	1.1	2.8	-0.3	1.2	0.8	1.7	-1.0	-0.8	1.2	1.0	1.6	1.0	0.9	1.4	0.8	0.1	1.1	1.2	0.5	-0.4
Average weekly champagne plus white wine intake	0.9	1.3	3.1	1.8	1.1	1.6	-0.8	1.1	1.3	-0.6	-1.2	0.2	-1.2	-1.3	1.2	-1.3	0.6	-0.7	-1.0	0.8	1.3
Eye problems/disorders: Glaucoma	0.9	1.0	3.5	0.0	0.5	0.2	-0.6	0.5	0.8	-1.4	-0.8	-1.9	-0.6	-0.8	-0.9	-0.8	-1.7	-1.5	-1.2	-1.4	-0.0
Supplements: Fish oil (including cod liver oil)	0.9	1.1	3.5	1.8	1.3	1.3	-0.1	0.2	0.4	0.6	-0.4	1.5	-0.1	-0.4	1.6	-0.4	1.7	0.4	0.2	1.9	1.2
Schizophrenia vs Biploar Disorder	0.8	1.0	4.6	-1.1	-1.2	-1.2	0.5	-0.8	-0.4	-0.8	0.5	-1.3	0.3	0.5	-2.1	0.4	-1.2	-0.2	-0.3	-1.5	-1.2
Crohns Disease (2017)	0.8	1.7	5.4	2.3	1.8	1.6	-1.3	1.3	1.2	-0.3	-1.4	0.1	-1.3	-1.3	1.2	-1.2	0.8	-0.8	-0.8	1.1	1.5
Age at First Birth	0.8	1.2	3.4	-1.5	-1.6	-1.3	1.3	-1.0	-1.0	0.2	1.1	0.1	0.9	1.0	-0.9	1.1	0.8	0.7	0.8	-1.9	-1.2
Average weekly spirits intake	0.8	1.0	2.2	-0.4	-0.2	-1.3	0.9	0.0	-1.0	1.4	1.1	1.3	1.1	1.0	0.3	1.0	1.2	1.5	1.3	-0.4	-0.6
Qualifications: CSEs or equivalent	0.8	1.0	4.6	1.1	2.1	1.0	-1.0	0.7	0.5	0.5	-0.3	0.8	-0.2	-0.4	1.6	-0.5	-0.2	0.2	0.1	2.1	1.0
Past tobacco smoking	0.8	1.5	3.8	0.3	-0.3	0.5	-1.3	1.2	1.2	-1.6	-1.0	-2.0	-0.9	-1.1	-1.0	-1.2	-1.7	-1.6	-1.5	-1.2	0.5
Pain all over the body in last month	0.8	0.9	3.0	-0.8	-1.2	-1.7	0.9	-1.1	-0.9	1.2	0.8	-0.1	1.1	1.0	-1.2	0.8	0.5	0.0	0.8	-0.5	-0.9
Qualifications: O levels/GCSEs or equivalent	0.8	1.4	3.1	-0.6	-0.6	-1.0	1.0	-1.5	-1.3	1.5	1.2	1.8	1.1	1.3	0.9	1.3	0.9	1.4	1.5	0.2	-0.6
Glaucoma (self-reported)	0.8	0.9	4.0	-0.3	0.5	0.6	-0.6	0.8	0.5	-1.2	-0.6	-2.0	-0.5	-0.6	-0.5	-0.5	-1.7	-1.3	-1.0	-1.5	-0.3
Mean time to correctly identify matches	0.8	1.5	2.7	1.2	0.8	1.3	-1.6	0.9	1.4	-1.1	-1.3	-0.5	-1.4	-1.4	0.4	-1.4	-1.3	-1.0	-1.2	0.9	1.6
Family relationship satisfaction	0.8	1.0	2.4	-0.8	-0.7	-1.6	1.2	0.2	-1.2	0.9	1.2	0.8	1.1	1.2	-0.6	1.2	1.0	0.9	1.2	-0.3	-1.1
Tinnitus: Yes, now most or all of the time	0.8	1.0	3.6	1.0	1.7	1.5	-1.3	0.1	0.5	-0.5	-0.8	0.3	-0.7	-0.8	1.6	-0.5	-0.6	-0.2	-0.3	1.9	0.9
Age started oral contraceptive pill	0.8	1.1	2.8	-1.1	-1.6	-1.3	1.0	-1.7	-1.0	0.5	0.9	0.1	0.8	1.0	-1.6	0.9	0.8	0.4	0.6	-0.4	-1.3
Depression (Nagel 2018)	0.7	1.0	3.8	-0.1	-0.8	-1.9	0.7	-0.5	-1.0	1.4	0.7	0.9	1.0	0.9	-1.0	0.9	1.6	0.5	1.2	1.0	-0.4
Prostate Cancer	0.7	1.0	2.2	0.7	0.3	0.6	-1.0	1.3	1.1	-1.4	-1.0	-1.5	-1.1	-1.1	-0.5	-1.2	-0.3	-1.2	-1.4	-0.8	0.5
Lupus	0.7	1.1	3.3	1.0	1.4	1.7	-0.9	1.8	0.8	-0.4	-1.1	0.0	-0.7	-0.9	0.9	-0.8	-0.6	-0.9	-0.7	1.6	1.3
Neuroticism (2016)	0.7	1.0	3.5	-0.3	-0.5	-1.5	0.8	-1.7	-0.9	1.0	0.6	0.9	0.8	0.9	-0.5	0.9	1.9	0.3	0.9	0.9	-0.5
Number of treatments/medications taken	0.7	1.2	3.9	1.5	1.4	2.0	-0.4	1.4	0.9	-0.1	-0.8	0.2	-1.0	-0.9	1.3	-0.9	-0.2	-0.4	-0.4	1.8	1.2
Trunk fat percentage	0.7	2.8	6.0	-1.8	-1.0	-1.9	2.4	-1.7	-2.1	1.3	1.9	-0.0	2.0	2.1	-1.3	2.1	0.8	0.9	1.8	-0.5	-2.2
Fluid intelligence score	0.7	1.4	3.9	-0.1	-1.0	-2.0	1.0	-1.0	-1.1	1.0	1.2	1.7	1.1	1.1	-0.2	1.1	1.4	1.6	1.5	0.8	-0.3
Noisy workplace	0.7	0.8	2.0	-0.6	-0.0	-0.7	0.8	-0.7	-1.1	1.1	0.9	1.1	1.1	1.1	0.5	1.1	1.4	0.9	1.3	0.4	-0.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.0	-1.3	-1.2	-1.4	1.4	-1.2	-1.3	0.8	1.3	0.2	0.9	1.3	-1.0	1.3	0.9	0.9	1.0	-0.8	-1.4
Shortness of breath walking on level ground	0.7	0.8	1.8	-1.3	-0.9	-1.0	1.2	-0.5	-1.1	0.7	0.9	-0.3	1.2	1.0	-0.7	1.1	-0.1	0.1	0.8	-0.8	-1.3
High cholesterol (Self-reported)	0.7	1.2	3.3	0.7	-0.4	-0.1	-1.2	0.3	1.2	-1.5	-1.2	-1.5	-1.3	-1.3	-0.7	-1.2	-1.0	-1.8	-1.5	-0.5	0.7
Bipolar Disorder (2018)	0.6	0.9	3.0	1.0	1.1	1.6	-0.4	1.7	0.6	-0.2	-0.8	0.5	-0.6	-0.7	1.7	-0.6	0.5	-0.5	-0.2	1.3	0.9
Alzheimer’s Disease (including proxy)	0.6	0.9	4.8	0.7	1.6	1.7	-0.4	2.2	0.7	-0.2	-0.7	0.1	-0.9	-0.7	0.9	-0.7	1.0	-0.2	-0.5	0.6	0.8
Major Depression (MDD)	0.6	0.7	1.8	0.4	0.5	0.5	-0.7	0.4	0.9	-1.3	-0.8	-1.1	-0.7	-0.8	-0.7	-0.8	-1.1	-1.3	-1.0	0.0	0.4
Allergy or Eczema	0.6	1.7	4.2	-1.6	-1.7	-0.9	1.5	-1.2	-1.4	0.8	1.4	0.3	1.5	1.3	-1.2	1.3	-0.3	1.0	1.1	-2.1	-1.5
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.2	1.2	0.9	0.3	-1.0	0.6	0.9	-0.6	-1.2	-0.2	-1.0	-1.0	0.1	-1.0	-0.1	-1.4	-0.8	1.5	1.2
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.2	-1.1	-1.2	-0.8	1.5	-1.2	-1.3	1.1	1.4	0.8	1.4	1.2	-0.7	1.2	-0.0	1.2	1.2	-1.1	-1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.6	1.2	-0.1	-0.2	-0.7	0.2	1.0	-0.3	-0.9	-0.3	-1.1	-0.9	-0.3	-1.0	1.6	-0.8	-0.6	1.0	1.3
Medication: Simvastatin	0.6	0.9	2.5	0.1	-0.4	-0.3	1.5	-0.5	-0.8	1.6	0.8	1.4	0.8	0.8	0.9	0.8	1.4	0.9	1.1	0.7	-0.4
Illnesses of siblings	0.6	0.9	2.7	-0.7	-1.2	-1.6	0.9	-1.1	-0.9	0.8	1.0	0.7	1.0	1.0	-0.4	1.0	0.4	0.9	1.0	-0.5	-0.7
Father’s age at death	0.6	0.8	4.8	0.8	-0.1	-0.0	0.2	0.8	-0.4	1.0	0.4	1.7	0.3	0.4	0.9	0.3	2.2	1.2	0.8	0.7	0.4
Illnesses of mother	0.6	0.7	2.2	-0.2	0.8	-0.1	0.5	-0.5	-0.7	1.3	0.6	1.4	1.1	0.8	1.5	0.8	0.9	0.5	1.1	0.3	-0.1
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.3	-0.6	0.1	-0.7	0.8	-0.1	-1.0	1.0	1.0	1.0	0.9	1.0	0.2	1.0	1.2	1.1	1.2	0.3	-0.5
Loud music exposure frequency	0.6	0.7	3.5	1.3	0.5	-0.0	-0.7	0.8	0.6	-0.3	-1.0	-0.3	-0.8	-0.7	-0.0	-0.6	-0.1	-1.2	-0.5	1.9	0.8
Medication: Paracetamol	0.6	1.0	4.0	-0.3	-0.1	-0.0	-0.8	0.8	0.8	-1.4	-0.9	-2.0	-0.6	-0.8	-1.2	-0.8	-0.9	-1.8	-1.2	-0.5	0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.0	1.1	1.2	1.4	-0.6	1.2	0.8	-0.3	-0.8	-0.4	-0.8	-0.8	0.8	-0.8	-1.2	-0.7	-0.7	-0.3	0.6
Medication: Ibuprofen	0.6	0.7	1.5	-1.2	-0.8	-1.2	1.0	-1.2	-0.9	0.7	1.0	0.0	0.8	0.9	-0.7	0.9	0.5	0.6	0.8	0.1	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.0	0.5	0.0	1.0	-0.7	1.3	0.9	-0.9	-1.0	-0.5	-0.9	-1.0	0.1	-0.9	-0.4	-0.6	-0.7	1.4	1.1
Age at last live birth	0.6	0.9	4.1	1.3	0.4	0.7	-0.8	0.3	1.0	-0.2	-0.9	0.7	-0.8	-0.8	1.0	-1.0	0.1	-0.5	-0.3	2.0	1.8
Leg pain on walking	0.6	0.7	3.7	-0.5	0.6	-0.9	0.5	-0.1	-1.0	0.8	0.8	0.2	0.8	0.9	-0.8	0.9	1.9	0.6	0.8	0.7	-1.0
Medication: Aspirin	0.6	0.8	2.6	0.3	0.4	0.5	1.0	-0.4	-0.7	1.3	0.8	1.6	0.6	0.7	1.2	0.6	1.0	1.0	1.1	0.9	-0.0
Medication: Aspirin	0.6	0.8	2.2	0.3	0.5	0.4	1.0	-0.3	-0.6	1.3	0.8	1.5	0.6	0.7	1.2	0.6	1.2	1.0	1.1	1.0	0.0
Miserableness	0.6	1.0	2.3	-1.1	-1.4	-1.5	1.2	0.1	-1.1	0.6	0.9	-0.5	1.2	1.2	-1.2	1.1	-0.0	0.1	0.8	-0.4	-1.3
Mother’s age at death	0.6	0.8	2.9	-0.8	-1.4	-1.3	0.0	-1.0	-0.1	-1.1	0.3	-1.3	-0.1	0.0	-1.2	0.1	-0.7	-0.2	-0.6	-1.7	-1.1
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.5	-1.1	-1.0	-0.5	0.6	0.7	-0.1	-0.9	0.1	-1.6	0.2	0.2	-1.5	0.1	-1.0	-0.8	-0.4	-1.6	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	3.2	0.3	-0.5	0.1	-0.1	0.3	0.7	-1.3	-0.9	-1.8	-0.9	-0.7	-1.1	-0.8	-0.4	-1.5	-1.1	-0.6	-0.1
Bipolar Disorder or Schizophrenia	0.5	1.3	4.5	-0.6	-1.1	-0.5	-0.5	1.2	0.6	-1.4	-0.5	-2.1	-0.6	-0.7	-1.7	-0.6	-1.8	-1.3	-1.2	-1.3	-0.5
Alzheimer’s Disease (in mother)	0.5	0.6	4.6	0.1	1.2	1.7	-0.5	2.1	0.6	-0.4	-0.5	-0.1	-0.4	-0.4	0.4	-0.6	-0.6	-0.3	-0.4	0.0	0.5
Body Mass Index (BMI) (2010)	0.5	0.7	1.5	-0.4	1.1	0.1	0.8	-1.1	-0.9	1.2	0.9	0.8	0.7	1.0	0.7	0.9	0.5	0.9	1.0	-0.0	-0.5
Coronary Artery Disease (CAD)	0.5	0.6	2.5	1.0	-0.1	0.3	-0.5	-0.3	0.8	-0.2	-1.1	-1.0	-0.8	-0.8	-0.5	-0.8	0.3	-1.6	-0.7	0.3	0.7
Fasting Glucose	0.5	0.6	2.5	0.8	0.8	1.6	-0.6	0.8	0.6	0.8	-0.4	0.6	-0.8	-0.5	1.3	-0.5	0.1	0.1	-0.2	1.0	0.8
Medication: Co-codamol	0.5	0.5	2.3	0.5	0.3	0.5	-0.5	0.5	0.7	-1.1	-0.8	-0.3	-0.5	-0.7	-0.7	-0.7	-0.9	-0.6	-0.7	1.5	0.7
Average weekly fortified wine intake	0.5	0.6	1.2	-0.8	-1.0	-1.1	0.9	-0.5	-0.7	1.1	0.8	0.4	0.8	0.9	-0.5	0.8	-0.1	0.6	0.8	0.9	-0.5
Medication: Levothyroxine sodium	0.5	0.8	1.3	-0.8	-0.6	-0.7	1.0	-0.5	-1.1	1.1	1.0	1.0	0.8	1.1	0.0	1.1	1.1	1.1	1.2	0.2	-0.7
Hearing difficulty/problems with background noise	0.5	0.7	3.9	0.3	0.1	0.5	0.4	-0.2	-0.5	1.1	0.6	1.2	0.6	0.6	1.2	0.6	1.2	0.5	1.0	2.0	0.0
Impedance of arm (right)	0.5	2.3	5.2	0.7	-1.0	-0.4	-1.7	1.1	1.6	-2.3	-1.7	-2.1	-2.0	-1.7	-1.6	-1.6	1.2	-1.7	-1.9	0.1	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.8	0.8	0.7	0.3	-0.3	1.1	0.3	0.3	-0.2	1.0	-0.1	-0.2	1.3	-0.3	1.3	-0.1	0.0	1.3	0.8
Impedance of arm (left)	0.5	2.1	4.3	0.9	-0.8	-0.2	-1.7	1.1	1.6	-2.1	-1.6	-1.6	-2.0	-1.7	-1.0	-1.6	1.6	-1.4	-1.7	0.4	1.3
Exposure to tobacco smoke outside home	0.5	0.7	3.0	-0.6	-0.7	-1.6	0.7	-0.2	-0.8	1.0	0.7	-0.0	0.7	0.8	-0.8	0.8	1.7	0.4	0.7	-0.7	-0.9
Medication for pain relief, constipation, heartburn	0.5	0.8	1.9	-0.8	-0.7	-1.3	0.7	-1.4	-0.9	0.6	1.0	0.6	0.9	0.9	-0.6	0.9	-0.8	1.2	0.7	-1.1	-1.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.7	0.7	1.3	0.8	-1.1	0.2	0.6	-0.1	-0.8	-0.0	-0.5	-0.6	1.0	-0.6	-0.3	-1.0	-0.5	1.2	0.9
Long-standing illness, disability or infirmity	0.5	0.7	2.2	-0.7	-1.1	-1.0	1.2	0.2	-0.8	0.4	0.8	-0.6	0.9	0.9	-1.5	0.7	-0.4	0.1	0.6	-0.7	-1.1
Mineral and other dietary supplements	0.5	0.6	2.1	-1.4	-0.6	-1.2	0.0	-0.4	-0.8	-0.0	0.8	-0.3	0.6	0.7	-0.9	0.8	-0.6	0.6	0.4	-1.2	-1.0
Ever taken oral contraceptive pill	0.5	0.5	1.7	-0.1	-0.1	-0.6	0.9	-0.5	-0.7	1.2	0.4	1.3	0.7	0.6	0.8	0.7	1.1	0.5	0.9	0.5	-0.2
Medication: Bendroflumethiazide	0.5	0.7	2.0	-1.0	0.0	0.2	1.1	-1.4	-1.1	0.9	0.9	0.3	0.9	0.8	0.2	1.0	-0.6	0.5	1.0	-0.5	-1.1
Ever smoked	0.5	0.8	1.6	-1.0	-0.9	-1.3	0.8	-1.1	-1.1	0.8	1.0	0.4	0.9	1.0	-0.5	1.0	0.5	0.9	0.9	-0.3	-1.2
Commuting to job workplace: Cycle	0.5	0.6	1.8	-0.3	-0.3	-0.7	0.8	-0.6	-0.8	1.3	0.9	0.9	0.7	0.9	0.3	0.8	1.2	0.8	1.0	-0.6	-0.3
Alzheimer’s Disease (in father)	0.4	0.4	1.7	-0.6	-0.7	-0.8	0.9	-0.3	-0.8	0.6	0.4	0.0	0.4	0.6	-0.7	0.8	1.3	0.4	0.6	0.1	-0.6
Irritable Bowel Disease (IBD)	0.4	1.0	3.1	1.7	1.0	1.1	-0.4	1.2	0.5	0.8	-0.6	0.9	-0.7	-0.4	1.6	-0.5	1.1	-0.1	0.1	1.5	1.2
Reaction Time	0.4	0.8	2.7	0.7	0.3	0.4	-1.3	0.4	0.9	-0.9	-0.9	-0.6	-0.9	-1.0	0.1	-0.9	-1.6	-0.8	-1.0	0.4	1.1
HbA1C	0.4	0.4	1.1	-0.4	-0.7	-0.0	1.1	-0.5	-0.8	0.6	0.5	0.7	-0.4	0.7	0.4	0.7	0.9	0.9	0.9	-0.4	-0.5
Rheumatoid Arthritis	0.4	0.6	2.3	-1.0	-0.7	-0.8	0.2	-0.3	-0.2	-0.6	0.4	-1.2	-0.1	0.3	-1.5	0.2	-0.9	-0.3	-0.3	-1.4	-0.9
Blood Eosinophil Count	0.4	3.0	7.5	1.6	0.4	1.7	-1.5	1.9	2.0	-1.1	-2.0	-1.5	-1.7	-1.8	-0.7	-2.0	-1.7	-2.7	-1.7	1.8	1.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.4	0.3	0.6	-0.2	0.4	1.4	-0.6	0.7	0.5	0.7	0.5	0.5	-0.0	0.5	1.6	0.7	0.8	0.6	-0.3
Medication for hormone replacement therapy	0.4	0.4	2.2	-0.7	-0.5	0.2	0.4	0.1	-0.1	-0.5	0.2	-1.2	0.2	0.2	-0.6	0.1	-1.1	-0.6	-0.2	-1.5	-0.6
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.4	0.9	0.1	0.6	-0.3	1.5	0.6	-0.5	-0.6	-0.5	-0.5	-0.5	0.4	-0.6	-0.0	-0.9	-0.5	0.7	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	4.9	0.6	2.0	1.5	-0.1	0.1	0.2	0.2	-0.4	0.7	-0.2	-0.2	2.2	-0.1	1.7	0.1	-0.1	0.2	0.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	-0.1	0.8	0.8	-1.0	0.6	0.3	-0.6	-0.6	-0.8	-0.3	-0.4	-0.1	-0.3	-1.1	-0.9	-0.6	0.5	0.2
Hair/balding pattern: Pattern 2	0.4	0.5	2.7	0.4	-0.9	-1.0	0.4	-1.3	-0.2	0.5	0.1	1.0	0.0	0.2	-0.1	0.2	1.7	0.4	0.6	0.3	0.2
Qualifications: None of the above	0.4	0.8	3.0	1.2	1.7	1.1	-1.1	1.4	0.8	-0.3	-0.8	-0.3	-0.9	-0.9	0.6	-0.9	0.7	-0.4	-0.7	0.4	0.8
Allergy	0.4	0.8	2.0	0.6	1.4	0.9	-1.2	0.7	1.0	-0.9	-1.0	-0.6	-1.1	-1.0	0.7	-1.0	0.4	-0.9	-0.9	0.8	0.8
Falls in the last year	0.4	0.5	1.5	-1.1	-0.5	-0.8	1.1	-0.2	-0.7	0.5	0.6	-0.2	0.8	0.7	-1.2	0.7	-0.3	0.2	0.5	-0.1	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.0	-1.0	-0.3	-0.8	1.0	-0.4	-0.9	0.7	0.9	0.1	0.8	0.8	-0.3	0.9	0.9	0.6	0.9	0.1	-0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.8	-0.9	-1.0	-1.3	0.6	-0.5	-0.6	0.3	0.8	-0.3	0.9	0.8	-0.6	0.6	0.6	0.6	0.3	-1.3	-0.9
High blood pressure (siblings)	0.4	0.6	3.0	0.6	1.3	1.7	-0.6	1.0	0.6	-0.4	-0.6	0.3	-0.6	-0.6	0.8	-0.6	0.6	-0.4	-0.4	1.2	0.6
Body fat percentage	0.4	1.5	3.3	-1.4	-0.7	-1.4	1.8	-1.4	-1.6	0.7	1.3	-0.5	1.4	1.4	-1.3	1.6	0.2	0.3	1.2	-0.3	-1.7
Number of children fathered	0.4	0.4	1.9	1.0	0.3	0.0	-0.8	-0.4	0.5	0.3	-0.6	0.6	-0.4	-0.5	0.8	-0.5	0.9	-0.1	-0.1	1.4	1.0
Pulse wave peak to peak time	0.4	0.5	1.6	0.2	0.4	0.2	0.6	-0.6	-0.5	1.2	0.5	1.2	0.9	0.5	0.9	0.4	0.2	0.9	0.8	1.1	0.0
Medication: Blood pressure	0.4	0.6	2.5	0.5	1.2	1.6	-0.2	1.2	0.3	0.2	-0.6	0.6	-0.6	-0.4	1.1	-0.2	-0.6	-0.5	0.0	1.4	0.7
Suffer from ‘nerves’	0.4	0.6	2.1	1.1	1.4	0.6	-0.4	0.8	0.6	-0.0	-0.7	0.6	-0.5	-0.6	0.9	-0.7	0.7	-0.3	-0.2	1.3	1.2
Knee pain experienced in last month	0.4	0.6	4.0	-1.0	-0.8	-1.2	0.5	0.1	0.0	-0.8	0.1	-1.4	-0.0	0.0	-2.0	-0.0	0.0	-0.6	-0.4	-0.6	-0.7
Illnesses of siblings: Diabetes	0.4	0.4	0.7	-0.6	0.7	-0.2	0.9	-0.4	-0.8	0.5	0.9	-0.0	0.7	0.8	-0.3	0.8	-0.7	0.6	0.7	-0.6	-0.8
Average weekly red wine intake	0.4	0.5	3.3	-0.4	-1.1	-1.8	0.6	-1.0	-0.5	0.7	0.5	0.4	0.6	0.5	-0.9	0.5	-0.0	0.3	0.6	0.0	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.6	1.1	1.3	1.4	-0.5	0.1	0.4	-0.3	-0.6	0.0	-0.8	-0.5	0.7	-0.4	0.0	-0.3	-0.3	1.6	0.9
Medication for cholesterol	0.4	0.6	2.0	1.1	1.4	0.0	-0.8	0.2	0.5	-0.2	-0.6	1.0	-0.6	-0.5	1.1	-0.5	1.3	0.5	-0.2	0.8	1.0
Breast cancer (self-reported)	0.4	0.5	2.3	0.5	-0.3	-0.2	-0.7	1.5	0.8	-0.8	-0.5	-0.7	-0.7	-0.6	-0.8	-0.8	0.9	-0.6	-0.8	-0.4	0.5
Osteoarthritis (self-reported)	0.4	0.5	1.7	-0.6	0.5	0.1	1.3	-0.7	-0.6	0.9	0.8	0.5	1.0	0.8	0.3	0.5	-0.9	0.5	0.6	-0.3	-0.7
Ever depressed for a whole week	0.4	0.5	1.4	0.9	-0.2	0.5	-0.7	1.2	0.8	-0.3	-0.6	-0.5	-0.5	-0.7	-0.4	-0.8	-0.6	-0.4	-0.6	0.8	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.3	-0.7	-0.5	-0.4	1.1	-1.5	-0.6	0.5	0.8	0.0	0.8	0.7	-0.6	0.6	-0.5	0.2	0.6	0.0	-0.7
Heart disease (siblings)	0.4	0.5	2.5	-0.3	-0.2	-0.2	-0.1	-0.3	0.4	-0.7	-0.5	-1.6	-0.5	-0.4	-1.0	-0.4	-0.4	-1.0	-0.8	-1.4	-0.3
Alcohol drinker status: Previous	0.4	0.5	1.7	1.3	1.2	0.4	-0.6	0.4	0.5	-0.0	-0.6	-0.2	-0.6	-0.7	0.1	-0.5	1.1	-0.1	-0.5	1.1	0.3
Ulcerative Colitis (UC)	0.3	0.6	2.4	0.8	-0.3	-0.0	0.3	0.6	-0.2	1.4	0.1	1.0	-0.0	0.3	1.0	0.2	1.2	0.3	0.7	1.6	0.7
Ovarian Cancer	0.3	0.4	2.8	0.1	-0.8	-1.0	0.4	-0.6	0.3	-0.5	-0.3	-0.5	0.0	-0.1	-1.7	-0.3	-0.2	-0.6	-0.4	0.3	-0.1
Smoking Status	0.3	0.6	1.7	-0.0	0.5	-0.4	0.8	-0.1	-0.7	1.2	0.8	1.3	0.6	0.8	1.1	0.7	0.4	1.3	0.9	0.8	-0.3
Neuroticism	0.3	0.8	2.2	0.1	0.2	-0.7	0.6	-0.2	-1.0	1.4	0.7	1.5	0.8	0.9	0.7	0.9	1.2	0.9	1.3	1.2	-0.2
Ever had hysterectomy (womb removed)	0.3	0.4	2.3	-0.3	-1.5	-1.4	0.4	0.0	-0.3	-0.1	0.3	-0.1	0.3	0.3	-0.9	0.3	-0.4	0.1	0.1	-0.7	-0.5
Alcohol usually taken with meals	0.3	0.5	1.6	1.2	0.3	-0.2	-0.6	-0.1	0.7	0.3	-0.6	1.0	-0.6	-0.6	0.6	-0.7	0.5	0.0	-0.2	1.2	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.1	0.7	1.6	1.2	-0.3	0.3	0.5	-0.2	-0.6	0.1	-0.6	-0.4	1.5	-0.5	1.8	-0.4	-0.4	0.1	0.4
Heart attack	0.3	0.4	1.7	-0.7	-0.4	-0.2	1.0	-1.3	-0.5	0.3	0.7	-0.2	0.7	0.6	-0.7	0.5	-0.9	0.1	0.4	-0.2	-0.7
Alcohol intake versus 10 years previously	0.3	0.4	1.7	0.6	0.9	1.1	-0.2	1.3	0.3	0.5	-0.0	0.3	0.1	-0.1	0.9	-0.3	-0.5	0.4	0.1	1.1	0.6
Asthma	0.3	0.6	1.5	1.2	-0.0	0.8	-0.5	1.2	0.9	-0.6	-0.7	-0.3	-0.6	-0.7	-0.0	-0.9	-0.6	-0.9	-0.6	0.9	1.0
Lung cancer (father)	0.3	0.4	2.1	0.4	1.4	1.3	-0.0	-0.1	0.2	-0.2	-0.3	0.3	-0.4	-0.3	1.5	-0.2	0.0	0.1	-0.1	0.5	0.4
Pulse wave Arterial Stiffness index	0.3	0.4	1.7	-0.7	-0.9	-0.7	-0.0	0.1	-0.2	-0.7	0.1	-0.9	-0.2	0.1	-1.1	0.2	-0.1	-0.4	-0.2	-1.3	-0.6
Hair/balding pattern: Pattern 4	0.3	0.6	1.6	0.9	0.8	0.5	-1.0	1.2	0.7	-0.6	-1.0	-0.3	-0.7	-0.8	0.3	-0.7	0.1	-0.7	-0.7	1.3	0.8
Wheeze or whistling in the chest in last year	0.3	0.5	3.0	-0.2	-0.5	-0.5	-0.3	0.2	-0.0	-0.7	-0.2	-1.2	-0.2	-0.0	-1.1	-0.0	-1.7	-0.7	-0.5	-0.6	-0.4
Heart disease (mother)	0.3	0.4	1.3	-0.2	-0.9	-1.0	0.4	-1.1	-0.4	-0.0	0.3	-0.5	0.1	0.3	-1.1	0.4	-0.1	0.2	0.1	-0.8	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.0	-0.9	-0.4	-0.6	1.0	-0.2	-0.6	-0.0	0.4	-0.5	0.5	0.7	-0.6	0.6	0.9	-0.5	0.4	-0.1	-0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.1	-0.2	-0.3	-0.1	-0.7	-1.0	0.4	-1.0	-0.6	-1.0	-0.4	-0.4	-1.0	-0.4	-0.8	-0.9	-0.6	0.0	0.2
Qualifications: nursing, teaching	0.3	0.4	1.5	-0.3	-0.7	-1.2	0.5	-0.4	-0.7	0.4	0.7	0.8	0.8	0.7	-0.2	0.7	0.2	0.8	0.7	-0.2	-0.7
Eye problems/disorders: Cataract	0.3	0.4	2.2	-0.3	-0.9	-1.4	-0.2	0.3	0.1	-0.7	0.1	-0.9	-0.1	0.0	-1.5	-0.1	-0.3	-0.4	-0.2	-0.6	-0.4
Osteoporosis (self-reported)	0.3	0.4	2.9	-0.1	-1.4	-0.4	0.7	0.5	-0.1	0.1	0.2	-0.6	0.2	0.2	-1.7	0.1	0.1	-0.3	-0.0	0.9	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	3.2	-0.1	0.8	-0.3	-0.0	-0.1	-0.4	1.3	0.9	1.4	0.6	0.7	0.7	0.4	1.8	1.4	1.0	-0.5	0.1
Alcohol drinker status: Never	0.3	0.3	2.0	0.0	-0.2	-1.4	0.1	-0.6	-0.5	0.4	0.6	0.0	0.4	0.4	-1.0	0.4	0.3	0.6	0.5	-0.1	-0.5
Basal cell carcinoma (self-reported)	0.3	0.4	1.8	-1.0	-0.6	0.3	0.5	0.5	-0.4	-0.5	0.4	-0.9	0.5	0.5	-0.7	0.4	-1.3	0.0	-0.2	-0.5	-0.9
HDL Cholesterol	0.2	0.3	1.8	0.0	0.6	0.0	0.1	0.5	-0.5	0.5	0.4	1.1	0.2	0.4	1.3	0.5	0.2	0.6	0.7	-0.1	0.1
Respiratory disease	0.2	0.4	1.4	1.2	0.1	0.6	-0.6	0.8	0.7	-0.5	-0.5	-0.3	-0.5	-0.6	0.0	-0.7	-0.1	-0.5	-0.6	0.6	0.6
Lung FEV1/FVC ratio	0.2	1.0	5.0	-0.3	0.6	-0.8	0.3	-0.6	-0.9	1.1	0.8	1.4	0.9	0.9	0.7	0.9	2.2	1.1	1.3	1.1	-0.1
Lung FVC	0.2	0.8	8.6	-0.5	-0.8	-1.1	0.1	0.3	-0.2	-0.1	0.5	-0.3	0.4	0.4	-1.3	0.3	-0.2	0.3	0.0	-2.9	-0.8
Chronotype (morning person)	0.2	0.4	1.1	-0.2	-0.2	-0.5	0.4	0.0	-0.7	0.9	0.7	0.9	0.5	0.7	0.5	0.7	1.1	1.0	0.9	-0.6	-0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.5	0.2	0.2	1.2	0.1	1.1	0.3	-0.2	-0.3	-0.0	-0.4	-0.4	0.2	-0.3	-0.5	0.0	-0.4	0.9	0.4
Systolic blood pressure, automated reading	0.2	0.6	3.3	-1.4	-1.2	-0.4	-0.2	-0.4	-0.1	-0.4	0.0	-1.0	0.2	0.1	-1.2	0.2	-1.8	-0.8	-0.2	-0.7	-0.5
Angina	0.2	0.3	1.4	0.4	0.1	-0.4	0.5	-0.9	-0.2	1.0	0.2	0.6	0.3	0.2	-0.2	0.2	1.2	0.1	0.4	0.5	-0.1
Diabetes (mother)	0.2	0.2	1.0	0.3	0.6	1.0	-0.2	0.8	-0.2	-0.2	0.2	0.0	0.0	0.0	0.4	0.1	-0.0	0.5	-0.1	-0.8	-0.4
Townsend deprivation index at recruitment	0.2	0.3	1.4	0.5	0.9	0.6	-0.4	1.2	0.5	-0.8	-0.5	-0.7	-0.6	-0.4	0.0	-0.5	-0.3	-0.6	-0.6	-0.0	0.3
Current tobacco smoking	0.2	0.3	3.3	-0.2	0.5	-0.1	-0.2	0.5	0.3	-0.6	-0.1	-0.8	-0.2	-0.1	-0.2	-0.3	-1.8	-0.3	-0.6	-0.5	-0.3
Fed-up feelings	0.2	0.3	0.9	-0.2	0.1	-0.2	0.5	0.2	-0.9	0.7	0.6	-0.0	0.8	0.8	0.2	0.9	0.5	0.2	0.7	-0.4	-0.8
High blood pressure	0.2	0.5	4.3	-0.1	0.8	1.3	-0.3	0.5	0.3	-0.3	-0.4	-0.9	-0.5	-0.5	-0.0	-0.2	-2.1	-0.8	-0.4	-0.2	-0.0
Supplements: Glucosamine	0.2	0.2	1.5	-0.1	-1.2	-0.2	0.8	0.0	-0.1	0.2	-0.1	-0.7	0.0	0.0	-0.5	0.2	-0.3	-0.6	0.1	-0.4	-0.2
Medication: Atenolol	0.2	0.3	1.4	0.2	0.3	0.7	0.3	0.2	-0.3	0.6	0.2	0.8	0.2	0.3	1.0	0.3	-1.2	0.2	0.5	0.3	-0.1
Nervous feelings	0.2	0.3	1.5	0.5	0.4	0.5	0.1	-0.8	-0.0	0.3	-0.0	0.7	-0.1	-0.0	0.7	-0.0	0.8	0.2	0.3	1.2	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.3	0.0	-0.1	-1.1	0.4	-0.8	-0.6	0.5	0.2	0.1	0.4	0.4	-0.7	0.5	0.2	-0.1	0.4	0.7	-0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.1	-0.1	-0.8	-1.1	-0.2	0.2	-0.1	0.4	0.2	-0.2	0.4	0.2	-0.8	0.1	-0.2	-0.1	0.2	0.6	-0.1
Mouth/teeth dental problems	0.2	0.4	2.8	-0.1	-0.5	0.5	-0.4	0.3	0.3	-0.6	-0.4	-0.8	0.1	-0.4	0.1	-0.3	-1.7	-0.8	-0.4	-0.6	-0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.7	0.6	0.7	0.7	-0.2	0.0	0.1	-0.0	-0.3	0.5	-0.2	-0.4	0.6	-0.2	-0.7	0.1	-0.1	0.9	0.6
Neuroticism score	0.2	0.4	3.9	0.9	0.8	0.1	-0.1	0.2	-0.1	0.4	-0.3	1.0	-0.0	-0.0	0.9	0.1	0.1	-0.1	0.4	2.0	0.7
Worrier / anxious feelings	0.2	0.4	2.1	-0.3	-0.1	-1.4	0.4	-1.2	-0.7	-0.1	0.4	0.0	0.3	0.4	-0.6	0.6	1.0	0.2	0.4	-0.6	-0.9
Medication: Cholesterol lowering	0.2	0.4	1.0	0.1	-0.1	-0.4	0.7	-0.6	-0.6	1.0	0.6	1.0	0.5	0.5	0.0	0.6	0.7	0.6	0.9	0.3	-0.3
Comparative body size at age 10	0.2	0.6	5.5	0.6	2.4	0.9	-0.6	0.6	0.3	-0.2	-0.3	-0.2	0.0	-0.3	1.5	-0.4	-0.9	0.0	-0.2	0.3	0.5
Age at first live birth	0.2	0.4	1.0	0.5	-0.3	0.1	-0.6	0.5	0.8	-0.6	-0.7	-0.3	-0.6	-0.7	-0.3	-0.8	-1.0	-0.7	-0.7	0.5	0.8
Qualifications: College or University degree	0.2	0.7	3.5	-0.6	-1.7	-1.9	0.7	-0.7	-0.7	0.1	0.6	0.5	0.7	0.7	-1.0	0.7	0.4	0.5	0.6	-0.5	-0.7
Eye problems/disorders: None of the above	0.2	0.2	1.2	0.2	-0.1	0.8	-0.0	0.0	0.0	0.3	-0.2	0.6	-0.0	-0.2	0.5	-0.1	0.6	0.1	0.1	1.1	0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.3	0.2	-0.3	-0.9	0.1	-1.1	-0.3	0.5	0.4	0.6	0.4	0.5	-0.4	0.4	0.4	0.6	0.4	0.2	-0.3
Emphysema/chronic bronchitis	0.2	0.2	1.6	0.3	-1.2	-0.8	-0.4	-0.4	0.1	-0.2	0.0	-0.4	-0.1	-0.0	-1.3	-0.1	-0.2	-0.2	-0.2	-0.2	-0.2
Angina (self-reported)	0.2	0.3	1.3	0.4	-0.1	-0.6	0.4	-0.8	-0.1	1.0	0.1	0.5	0.2	0.2	-0.4	0.1	1.1	-0.0	0.4	0.7	0.0
Medication: Omeprazole	0.2	0.3	1.0	0.2	-0.7	-0.4	0.4	-0.2	0.0	-0.5	-0.3	-1.0	-0.3	-0.1	-0.8	-0.1	0.6	-0.8	-0.4	-0.5	-0.5
Medication: Seretide 50 evohaler	0.2	0.2	0.8	0.4	0.0	0.6	-0.0	0.3	0.5	-0.3	-0.5	-0.7	-0.2	-0.3	-0.3	-0.5	-0.1	-0.9	-0.6	0.3	0.1
Overall health rating	0.2	0.4	2.2	-0.1	0.4	0.0	-0.3	1.5	0.2	-0.5	-0.4	-1.2	-0.3	-0.2	-0.7	-0.2	-0.7	-1.2	-0.5	-0.2	-0.3
Chest pain or discomfort	0.2	0.3	1.4	-0.2	-0.9	-0.8	0.4	-1.2	-0.0	-0.1	-0.1	-0.5	-0.1	0.1	-1.1	0.0	-0.7	-0.5	-0.2	0.3	-0.3
Supplements: Vitamin C	0.2	0.2	0.7	0.0	0.0	0.2	0.8	0.1	-0.3	0.9	0.3	0.5	0.4	0.4	0.4	0.3	0.3	0.3	0.5	0.8	0.2
Mood swings	0.2	0.4	3.0	0.7	0.7	0.4	-0.1	0.9	-0.2	0.5	-0.3	0.5	0.2	0.1	0.6	0.2	-0.4	-0.3	0.5	1.7	0.4
Loneliness, isolation	0.2	0.3	1.4	0.2	0.3	0.1	-0.2	1.1	0.2	-0.4	-0.7	-0.4	-0.3	-0.3	-0.3	-0.3	-0.1	-1.2	-0.3	0.7	0.4
Ever had bowel cancer screening	0.2	0.2	1.7	-0.2	-1.3	-0.3	-0.1	-0.3	0.2	-0.0	-0.2	-0.3	-0.2	-0.1	-1.1	-0.2	0.1	-0.3	-0.2	0.4	0.1
Smoking status: Current	0.2	0.3	2.7	-0.1	0.7	0.1	-0.1	0.6	0.3	-0.5	-0.2	-0.5	-0.2	-0.1	0.1	-0.3	-1.7	-0.3	-0.5	-0.3	-0.1
Guilty feelings	0.2	0.3	2.1	0.3	-0.2	-1.2	-0.5	0.1	0.2	0.0	-0.4	0.3	-0.2	-0.2	-0.8	-0.1	-0.4	-0.3	-0.1	1.4	0.5
Financial situation satisfaction	0.2	0.2	0.7	-0.0	0.6	-0.2	0.2	0.6	-0.5	0.8	0.5	0.2	0.5	0.5	-0.2	0.5	0.4	0.4	0.6	0.7	-0.3
Medication: Blood pressure	0.2	0.4	1.3	-1.0	-0.5	0.0	0.6	-0.8	-0.7	0.5	0.7	-0.4	0.7	0.6	-0.9	0.7	-0.7	0.2	0.4	-0.5	-1.1
Illnesses of father: High blood pressure	0.2	0.3	2.3	-0.6	-0.3	0.8	0.3	0.3	-0.0	0.2	0.2	-0.4	0.1	0.1	-0.2	0.1	-1.5	-0.3	-0.1	-0.8	-0.5
Unable to work because of sickness or disability	0.2	0.3	1.7	0.2	1.3	0.1	-0.0	-0.0	-0.4	0.8	0.3	0.7	0.4	0.4	0.5	0.4	0.5	0.6	0.6	0.3	-0.0
Vascular/heart problems diagnosed by doctor	0.2	0.4	3.4	0.0	-0.9	-1.5	0.0	-0.5	-0.2	-0.1	0.1	0.5	0.3	0.3	-0.2	0.1	1.8	0.5	0.1	0.1	0.0
Cholesterol lowering medication	0.2	0.3	1.3	-0.6	-1.0	-0.2	0.6	-0.5	-0.3	0.1	0.2	-0.7	0.1	0.3	-0.3	0.3	-0.6	-0.7	0.0	-1.1	-0.7
Depressed Affect (Nagel 2018)	0.1	0.3	1.2	-0.1	-0.8	-0.7	0.2	0.8	-0.5	0.4	0.0	-0.6	0.5	0.4	-1.1	0.4	-0.1	-0.7	0.3	0.5	-0.4
Neuroticism (Nagel 2018)	0.1	0.2	1.5	0.0	-0.6	-1.0	0.0	0.1	-0.5	0.2	-0.0	-0.4	0.4	0.2	-1.2	0.4	-0.4	-0.6	0.1	0.2	-0.2
Worry (Nagel 2018)	0.1	0.1	0.4	0.5	0.6	-0.3	-0.2	-0.1	-0.2	0.4	-0.1	0.6	0.2	0.0	0.3	0.2	0.2	0.1	0.3	0.6	0.3
Breast Cancer	0.1	0.2	1.1	-0.3	0.0	-0.4	0.5	-1.1	-0.5	0.1	0.4	-0.3	0.5	0.4	-0.3	0.6	-0.3	0.1	0.2	-0.9	-0.7
Triglycerides	0.1	0.1	0.5	0.1	-0.6	-0.6	-0.6	0.4	-0.0	-0.0	-0.1	-0.4	-0.0	-0.1	-0.7	0.0	0.5	-0.5	-0.0	0.1	0.0
Blood Platelet Count	0.1	0.8	2.3	-0.9	-1.0	0.1	1.5	-1.2	-1.0	1.0	0.8	0.8	0.9	1.0	0.4	1.0	0.8	0.2	1.1	0.2	-0.7
Blood Red Count	0.1	1.3	6.1	1.1	0.9	1.3	-1.3	0.8	0.8	0.2	-0.9	0.5	-0.8	-0.8	1.9	-0.8	-1.1	-0.8	-0.2	2.5	1.6
Systolic Blood Pressure	0.1	0.7	3.2	-1.6	-1.4	-0.2	0.2	-0.7	-0.6	0.3	0.5	-0.1	0.6	0.5	-0.6	0.7	-1.8	-0.2	0.4	-1.1	-0.9
Cardiovascular Disease	0.1	0.3	2.5	-0.3	0.4	1.1	0.6	-0.3	-0.4	0.4	0.4	0.1	0.0	0.2	0.4	0.5	-1.6	0.1	0.4	0.3	-0.5
Tanning	0.1	1.3	4.5	-0.8	-2.0	-0.7	1.3	-2.1	-1.0	0.5	1.1	0.4	0.9	0.9	-0.5	1.0	-0.9	0.9	0.8	-1.4	-1.2
Age when periods started (menarche)	0.1	0.2	0.8	0.0	-0.9	-0.1	-0.5	-0.5	0.2	0.1	-0.2	0.3	-0.1	-0.3	-0.1	-0.3	0.9	-0.1	-0.2	0.7	0.4
Stomach or abdominal pain in last month	0.1	0.1	0.7	-0.2	-0.1	-0.8	-0.2	0.0	-0.1	-0.2	-0.2	-0.0	-0.0	0.1	-0.7	0.1	0.1	-0.6	0.1	0.7	0.0
High blood pressure (mother)	0.1	0.1	0.5	0.0	0.7	0.5	-0.1	0.5	0.2	-0.1	0.0	-0.1	-0.2	-0.1	0.1	-0.2	-0.7	0.1	-0.2	0.2	-0.0
Had menopause	0.1	0.1	0.3	-0.1	-0.6	0.3	0.6	-0.6	-0.1	0.4	0.2	0.4	0.1	0.1	-0.0	0.1	0.5	0.3	0.2	0.5	-0.1
Had other major operations	0.1	0.1	0.5	0.2	0.6	0.4	0.3	0.4	0.0	0.4	0.3	0.6	0.2	0.1	-0.0	-0.0	0.4	0.7	0.3	0.7	0.1
Hair/balding pattern: Pattern 3	0.1	0.2	0.5	-0.2	0.1	-0.3	-0.0	0.6	-0.3	0.7	0.5	0.6	0.4	0.4	0.3	0.3	-0.2	0.7	0.5	-0.5	-0.2
Pulse wave reflection index	0.1	0.2	2.5	-0.0	0.4	-0.4	0.2	0.1	-0.1	0.0	0.1	-0.3	-0.1	0.2	-0.1	0.0	1.6	-0.1	0.0	-0.3	-0.2
Medication: Amlodipine	0.1	0.1	0.9	-0.1	-0.5	0.8	0.2	0.0	-0.1	0.2	-0.0	0.4	-0.2	0.1	0.1	0.1	0.0	-0.1	0.4	0.9	0.2
Leg fat percentage (right)	0.1	0.4	1.1	-0.7	-0.2	-0.5	0.7	-0.8	-0.6	0.0	0.3	-0.8	0.5	0.5	-1.1	0.6	-0.4	-0.6	0.4	-0.0	-0.7
Migraine (self-reported)	0.1	0.2	1.2	0.1	0.2	0.1	-0.1	0.2	-0.3	0.2	0.1	-0.2	-0.1	0.1	0.5	0.3	1.1	0.0	0.2	-1.0	-0.4
Alcohol intake frequency.	0.1	0.2	0.9	0.7	1.0	-0.5	-0.0	-0.3	-0.1	0.4	0.3	-0.5	0.3	0.1	-0.0	0.1	-0.1	0.3	0.1	-0.5	-0.3
Hypertension (Self-reported)	0.1	0.4	3.3	-0.1	0.8	1.3	-0.3	0.4	0.1	-0.2	-0.3	-0.6	-0.5	-0.4	0.1	-0.1	-1.8	-0.5	-0.2	-0.0	-0.1
Asthma (self-reported)	0.1	0.2	0.7	0.9	-0.3	0.3	-0.1	0.8	0.4	-0.2	-0.3	-0.1	-0.3	-0.3	-0.1	-0.5	-0.3	-0.5	-0.3	0.6	0.5
Number of self-reported non-cancer illnesses	0.1	0.2	1.0	0.7	0.9	1.0	-0.2	0.3	0.2	0.1	-0.2	0.2	-0.4	-0.2	0.6	-0.2	-0.6	-0.3	-0.0	0.6	0.3
Leg fat percentage (left)	0.1	0.2	0.8	-0.4	0.4	-0.1	0.4	-0.5	-0.3	-0.3	-0.0	-0.9	0.2	0.1	-0.8	0.3	-0.4	-0.9	0.1	0.1	-0.4
Number of operations (self-reported)	0.1	0.1	0.5	0.1	0.6	-0.1	0.3	-0.6	0.0	-0.5	-0.1	-0.2	-0.2	-0.1	-0.4	0.0	-0.7	0.0	-0.2	0.1	-0.3
Hair Pigment	0.0	0.6	2.1	-1.4	0.8	-0.3	1.0	-0.1	-0.9	0.6	0.6	0.4	0.8	0.7	0.8	0.9	0.8	0.8	0.7	-0.5	-0.8

Hub : Genes

HIF1AN

Models

Trait associations