TWAS hub - NDUFB8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.1110	0.0360	1.5e-05	0.027	NA	0.019	NA	0.017	0.0038	NA	0.014	NA	0.017
2	TCGA	Brain Lower Grade Glioma	0.0208	0.0187	5.6e-03	0.005	0.011	0.004	NA	0.005	0.0750	0.016	0.110	NA	0.074

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pulse rate, automated reading	11.1	36.0	42.0	-6.5	-5.5
Chronic bronchitis/emphysema (father)	10.4	12.1	17.2	4.1	2.7
Birth weight	7.2	15.7	16.6	-3.8	-4.1
Hearing difficulty/problems: Yes	6.3	9.7	9.9	-3.1	-3.1
Number of incorrect matches in round	5.8	9.6	11.8	3.4	2.7
Diabetes (self-reported)	5.7	8.9	13.5	-2.0	-3.7
Diabetes (father)	5.4	6.7	9.8	-1.9	-3.1
Neck or shoulder pain in last month	5.3	7.6	9.2	-3.0	-2.4
Medication: Metformin	4.8	6.8	11.4	-1.5	-3.4
Average weekly beer plus cider intake	4.7	6.8	7.0	2.6	2.6
Leg fat-free mass (left)	4.3	22.8	42.8	-1.7	-6.5
Leg predicted mass (left)	4.3	22.9	42.6	-1.8	-6.5
Leg fat-free mass (right)	4.3	22.8	43.0	-1.6	-6.6
Type 2 Diabetes (T2D) (2018)	4.2	7.9	12.6	-1.8	-3.5
Eye problems/disorders: Diabetes related eye disease	4.1	4.5	5.2	-2.3	-1.9
Leg predicted mass (right)	4.1	22.0	41.8	-1.5	-6.5
Qualifications: A levels/AS levels or equivalent	3.8	8.5	9.8	-3.1	-2.7
Birth weight of first child	3.7	6.6	9.8	-1.9	-3.1
Frequency of depressed mood in last 2 weeks	3.6	5.0	8.9	3.0	1.1
Diabetes diagnosed by doctor	3.6	5.9	9.5	-1.5	-3.1
Taking other prescription medications	3.4	5.3	5.4	2.3	2.3
Whole body fat-free mass	3.4	19.3	37.3	-1.1	-6.1
Basal metabolic rate	3.4	18.7	35.9	-1.3	-6.0
Whole body water mass	3.3	18.9	36.6	-1.1	-6.0
Sitting height	3.2	22.7	40.1	-2.3	-6.3
Comparative height size at age 10	3.2	17.5	30.8	-2.1	-5.5
Fractured/broken bones in last 5 years	3.2	4.1	5.1	-1.7	-2.3
Peak expiratory flow (PEF)	3.1	7.1	9.8	-2.1	-3.1
Chronic bronchitis/emphysema (mother)	3.1	3.6	4.5	2.1	1.7
Arm fat-free mass (right)	3.0	15.2	29.8	-0.9	-5.5
Health satisfaction	3.0	3.9	4.4	-2.1	-1.8
Impedance of leg (left)	2.9	14.2	25.9	1.6	5.1
Hair/balding pattern: Pattern 2	2.9	3.6	7.2	-2.7	-0.3
Commuting to job workplace: Walk	2.9	3.1	3.9	-2.0	-1.5
Intelligence (Savage-Jansen 2018)	2.8	8.8	12.7	-3.6	-2.2
Maternal smoking around birth	2.8	4.1	5.9	2.4	1.5
Trunk fat-free mass	2.8	16.3	32.0	-0.7	-5.7
Number of live births	2.8	4.0	4.9	2.2	1.8
Prospective memory result	2.8	3.5	4.8	2.2	1.5
Trunk predicted mass	2.8	16.2	31.8	-0.7	-5.6
Arm predicted mass (right)	2.8	14.4	28.0	-0.8	-5.3
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.8	11.4	-0.5	-3.4
Back pain experienced in last month	2.8	4.1	4.3	2.1	2.0
Arm fat-free mass (left)	2.8	14.2	27.9	-0.7	-5.3
Arm predicted mass (left)	2.8	14.3	27.6	-1.0	-5.3
Verbal and Numeric Reasoning (VNR)	2.7	6.4	8.2	-2.9	-2.2
Hearing aid user	2.7	3.0	5.0	-1.0	-2.2
Fluid intelligence score	2.6	5.5	8.9	-3.0	-1.4
Weight	2.6	12.9	24.3	-1.2	-4.9
Medication: Atorvastatin	2.6	3.3	3.3	1.8	1.8
Pulse rate	2.5	4.2	6.0	-2.4	-1.6
Wears glasses or contact lenses	2.5	2.9	3.8	2.0	1.4
Ulcerative Colitis	2.4	3.4	5.6	2.4	1.1
Hand grip strength (right)	2.4	6.6	11.0	-1.5	-3.3
LDL Cholesterol	2.3	3.6	4.9	1.5	2.2
Hand grip strength (left)	2.2	5.7	8.6	-1.6	-2.9
Forced expiratory volume in 1-second (FEV1)	2.2	7.5	12.9	-1.4	-3.6
Risk taking	2.2	3.2	4.1	2.0	1.5
Impedance of leg (right)	2.1	9.9	19.0	1.0	4.4
Mouth/teeth dental problems: Dentures	2.1	3.5	3.6	-1.8	-1.9
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	4.2	2.1	1.1
Loneliness, isolation	2.1	3.0	5.5	2.4	0.6
Ever had prostate specific antigen (PSA) test	2.1	2.5	4.4	0.7	2.1
Hip circumference	2.0	8.7	15.0	-1.6	-3.9
Standing height	2.0	19.6	38.2	-1.0	-6.2
Tense / ‘highly strung’	2.0	3.3	3.8	1.7	2.0
Worry too long after embarrassment	2.0	3.3	3.6	1.9	1.7
Smoking status: Previous	2.0	3.0	3.8	-1.9	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.0	10.6	-1.2	-3.3
Relative age voice broke	1.8	2.7	4.9	0.7	2.2
Medication: Allopurinol	1.8	2.5	3.1	1.7	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	4.1	2.0	0.5
Irritability	1.8	3.0	4.9	-1.1	-2.2
Pack years of smoking	1.8	2.6	2.9	1.7	1.5
Heel T-Score	1.7	13.7	27.0	0.6	5.2
Relative age of first facial hair	1.7	3.5	4.7	1.5	2.2
Average weekly fortified wine intake	1.7	2.0	3.4	-1.8	-0.8
Serious illness, injury or assault to yourself	1.7	2.0	3.2	-0.9	-1.8
Forced vital capacity (FVC)	1.7	6.6	11.2	-1.4	-3.4
Mean Putamen Volume	1.6	1.9	2.9	-0.9	-1.7
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	2.8	1.7	-1.6
Headache pain in last month	1.6	2.8	2.8	-1.7	-1.7
Forced vital capacity (FVC), Best measure	1.6	6.0	10.5	-1.2	-3.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.0	2.9	1.7	1.1
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.8	2.0	1.4	1.3
Mean time to correctly identify matches	1.6	3.0	4.3	2.1	1.3
Arm fat mass (left)	1.6	6.6	11.4	-1.3	-3.4
Mother’s age at death	1.6	2.0	4.1	-2.0	0.1
Hair/balding pattern: Pattern 3	1.5	2.2	4.1	2.0	-0.5
Happiness	1.5	1.8	2.7	-1.0	-1.6
Gout (self-reported)	1.5	2.1	2.2	1.5	1.4
Number of full sisters	1.5	1.8	2.7	-1.6	-0.9
Medication for cholesterol	1.5	2.2	4.4	-2.1	0.2
Medication: Paracetamol	1.5	2.3	2.9	1.3	1.7
Hypothyroidism (self reported)	1.4	3.2	4.6	-1.3	-2.1
Severe depression (siblings)	1.4	1.6	1.7	1.3	1.2
Arm fat mass (right)	1.4	5.7	10.1	-1.1	-3.2
Length of working week for main job	1.4	1.6	1.9	-1.4	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	2.9	1.2	1.7
Had major operations	1.4	1.6	1.7	-1.2	-1.3
Commuting to job workplace: Public transport	1.4	1.7	1.9	-1.2	-1.4
Diastolic blood pressure, automated reading	1.4	4.2	4.8	-1.9	-2.2
Impedance of whole body	1.4	7.2	13.7	0.8	3.7
Height	1.3	25.0	49.3	-0.9	-7.0
Trunk fat mass	1.3	5.5	10.2	-0.9	-3.2
Qualifications: O levels/GCSEs or equivalent	1.3	2.0	2.1	-1.4	-1.4
Qualifications: nursing, teaching	1.3	2.1	3.5	-1.9	-0.8
Cholesterol lowering medication	1.3	1.9	3.9	2.0	0.0
Supplements: Calcium	1.3	1.4	2.4	1.6	0.6
Pack years adult smoking proportion	1.2	1.8	1.9	1.4	1.3
Medication: Ramipril	1.2	1.5	2.7	-0.6	-1.6
Illnesses of mother	1.2	1.5	2.3	-1.5	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	2.2	1.5	0.9
Whole body fat mass	1.2	5.0	8.8	-1.1	-3.0
High cholesterol (Self-reported)	1.2	2.0	2.1	1.4	1.4
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	1.7	-1.2	-1.3
Bipolar Disorder (2011)	1.1	1.1	2.0	-0.4	-1.4
BMI	1.1	6.3	10.6	-1.4	-3.2
Ever used hormone-replacement therapy (HRT)	1.1	1.4	2.7	1.6	0.2
Medication: Co-codamol	1.1	1.2	1.9	1.4	0.8
Waist circumference	1.1	4.0	7.3	-0.8	-2.7
Past tobacco smoking	1.1	1.9	2.0	1.4	1.4
Depression (self-reported)	1.1	1.3	1.4	1.2	1.1
Exposure to tobacco smoke at home	1.1	1.2	2.4	-0.2	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	1.8	0.9	1.3
Primary Biliary Cirrhosis	1.0	1.4	2.0	0.8	1.4
Blood White Count	1.0	7.5	9.2	2.4	3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.6	0.5	-1.6
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	1.9	1.4	0.6
Illnesses of siblings	1.0	1.4	2.0	-1.4	-0.9
Shortness of breath walking on level ground	1.0	1.2	1.7	-1.3	-0.8
Leg fat mass (right)	1.0	4.0	6.8	-1.1	-2.6
Prostate Cancer	0.9	1.2	1.5	0.9	1.2
Fasting Glucose	0.9	1.1	2.1	1.4	0.3
Average weekly spirits intake	0.9	1.1	1.6	-0.7	-1.3
Supplements: Zinc	0.9	0.9	1.9	0.0	-1.4
Time employed in main current job	0.9	1.1	1.4	-0.9	-1.2
Age at last live birth	0.9	1.3	2.2	1.5	0.7
Friendships satisfaction	0.9	1.1	2.2	-0.3	-1.5
Illnesses of father: None of the above (group 1)	0.9	1.1	2.2	-0.2	1.5
Leg fat mass (left)	0.9	3.4	5.9	-0.9	-2.4
Bipolar Disorder or Schizophrenia	0.8	1.9	2.9	1.7	1.0
Reaction Time	0.8	1.5	1.9	1.4	1.0
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.7	-0.4	-1.3
Family relationship satisfaction	0.8	0.9	1.4	-0.7	-1.2
Arm fat percentage (left)	0.8	3.0	4.0	-1.4	-2.0
Ever had bowel cancer screening	0.8	1.0	1.9	1.4	0.2
Crohns Disease (2012)	0.7	1.2	1.4	1.0	1.2
Current tobacco smoking	0.7	1.2	2.2	1.5	0.4
Body mass index (BMI)	0.7	2.8	5.1	-0.7	-2.3
Noisy workplace	0.7	0.8	1.1	-0.7	-1.1
Medication: Lansoprazole	0.7	0.7	1.4	0.2	1.2
Blood clot in the leg (DVT)	0.7	1.0	1.2	-0.8	-1.1
Comparative body size at age 10	0.7	1.9	3.7	1.9	0.2
Number of full brothers	0.7	0.9	1.8	-0.2	-1.3
Suffer from ‘nerves’	0.7	1.1	2.0	1.4	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.2	0.4	1.1
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	1.1	0.8	1.0
Heart disease (siblings)	0.7	0.8	1.2	1.1	0.7
Schizophrenia (2018)	0.6	1.2	1.6	1.3	0.8
Age at First Birth	0.6	0.9	0.9	-0.9	-0.9
Coronary Artery Disease (CAD)	0.6	0.7	0.8	0.8	0.9
HDL Cholesterol	0.6	0.9	1.4	-1.2	-0.7
Blood Eosinophil Count	0.6	4.9	5.4	2.3	2.1
Number of treatments/medications taken	0.6	1.1	1.9	1.4	0.5
Medication for hormone replacement therapy	0.6	0.7	1.3	1.1	0.1
Hayfever, allergic rhinitis or eczema	0.6	1.4	1.6	-1.1	-1.3
Pain all over the body in last month	0.6	0.6	0.8	0.9	-0.7
Arm fat percentage (right)	0.6	2.5	3.4	-1.3	-1.8
Medication: Paracetamol	0.6	1.0	1.7	0.7	1.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	0.9	0.9	0.7
Medication: Gliclazide	0.6	0.7	1.2	0.5	-1.1
Smoking status: Current	0.6	1.0	1.9	1.4	0.3
Eye problems/disorders: Glaucoma	0.6	0.7	1.2	-0.4	1.1
Commuting to job workplace: Cycle	0.6	0.7	0.8	-0.7	-0.9
Bipolar Disorder (2018)	0.5	0.8	1.3	1.2	0.5
Depressed Affect (Nagel 2018)	0.5	1.1	2.1	1.5	-0.1
Depression (Nagel 2018)	0.5	0.8	0.9	0.8	-0.9
Major Depression (MDD)	0.5	0.6	1.0	0.4	1.0
Lupus	0.5	0.7	0.8	0.8	0.9
Neuroticism (2016)	0.5	0.7	0.9	-0.9	-0.7
Schizophrenia (2014)	0.5	1.0	1.2	1.1	0.9
Systolic Blood Pressure	0.5	2.4	4.6	-2.1	-0.4
Allergy or Eczema	0.5	1.2	1.4	-1.0	-1.2
Chronotype (morning person)	0.5	1.2	1.6	-1.3	-0.9
Worrier / anxious feelings	0.5	1.0	1.7	-1.3	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	0.6	-0.8	-0.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	1.3	-0.9	-1.1
Medication for pain relief, constipation, heartburn	0.5	0.9	1.0	-1.0	-0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.8	0.9	0.7
Handedness (chirality/laterality): Left-handed	0.5	0.5	0.7	0.8	0.6
Mood swings	0.5	0.9	1.8	1.3	-0.1
Medication: Lisinopril	0.5	0.6	1.1	0.3	1.1
Alcohol drinker status: Never	0.5	0.6	0.8	-0.9	-0.6
Ever smoked	0.5	0.9	1.0	-1.0	-0.9
Myopia	0.5	0.7	1.3	0.3	1.1
Breast Cancer	0.4	0.9	1.6	-1.3	-0.4
HbA1C	0.4	0.4	0.8	0.3	-0.9
Neuroticism	0.4	1.0	1.0	1.0	-1.0
Sensitivity / hurt feelings	0.4	0.7	0.8	0.8	0.9
Trunk fat percentage	0.4	1.7	2.9	-0.7	-1.7
Medication: Levothyroxine sodium	0.4	0.6	1.3	0.0	-1.1
Had menopause	0.4	0.5	0.9	0.9	-0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.0	1.0	0.1
Neuroticism score	0.4	0.7	1.5	1.2	-0.1
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.0	0.2	-1.0
Loud music exposure frequency	0.4	0.4	0.7	0.3	0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.0	-1.0	-0.5
Glaucoma (self-reported)	0.4	0.5	0.7	-0.5	0.9
Medication: Amlodipine	0.4	0.5	1.0	1.0	-0.1
Qualifications: College or University degree	0.4	1.2	2.0	-1.4	-0.5
Eye problems/disorders: None of the above	0.4	0.5	1.0	1.0	-0.0
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.9	-0.9	-0.4
Chest pain or discomfort	0.4	0.6	1.1	1.1	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.9	0.9	-0.2
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.8	0.2	0.9
Medication: Aspirin	0.4	0.5	0.9	0.2	-1.0
Medication: Aspirin	0.4	0.5	0.9	0.3	-0.9
Average weekly champagne plus white wine intake	0.4	0.6	1.0	0.5	1.0
Medication: Bendroflumethiazide	0.4	0.6	0.9	0.5	-0.9
Pain experienced in last month	0.4	0.6	0.7	0.7	0.8
Alzheimer’s Disease (in father)	0.3	0.3	0.3	0.5	-0.5
Alzheimer’s Disease (including proxy)	0.3	0.4	0.7	0.8	0.5
Crohns Disease (2017)	0.3	0.7	0.8	0.8	0.9
Irritable Bowel Disease (IBD)	0.3	0.6	1.2	1.1	0.1
Ulcerative Colitis (UC)	0.3	0.6	1.0	1.0	-0.4
Body Mass Index (BMI) (2010)	0.3	0.5	0.9	0.1	-1.0
Waist Hip Ratio (WHR)	0.3	1.2	1.8	0.7	1.3
Smoking Status	0.3	0.6	0.9	-0.5	-1.0
Ever had hysterectomy (womb removed)	0.3	0.3	0.5	0.7	-0.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.3	0.6	0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.6	0.4	0.8
Allergy	0.3	0.6	0.9	0.5	1.0
Medication: Simvastatin	0.3	0.5	0.9	0.1	-1.0
Impedance of arm (right)	0.3	1.6	3.3	0.0	1.8
Father’s age at death	0.3	0.4	0.5	-0.5	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.6	-0.8	0.2
Impedance of arm (left)	0.3	1.4	2.8	-0.2	1.7
Breastfed as a baby	0.3	0.4	0.8	0.9	-0.2
Pulse wave reflection index	0.3	0.4	0.8	0.9	-0.0
Number of children fathered	0.3	0.3	0.6	-0.8	0.3
Pulse wave peak to peak time	0.3	0.4	0.5	-0.5	-0.7
Medication: Blood pressure	0.3	0.5	0.9	1.0	0.2
Migraine (self-reported)	0.3	0.3	0.6	-0.8	-0.2
Medication: Ibuprofen	0.3	0.3	0.6	-0.1	-0.8
Alcohol intake frequency.	0.3	0.7	1.4	-1.2	-0.3
Leg pain on walking	0.3	0.3	0.6	-0.2	-0.8
Illnesses of siblings: Diabetes	0.3	0.3	0.7	-0.0	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	0.9	0.4	-1.0
Respiratory disease	0.2	0.5	0.8	-0.9	0.6
Lung FEV1/FVC ratio	0.2	1.2	1.3	1.1	-1.0
Tanning	0.2	2.1	3.2	-1.8	-1.0
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.5	-0.2	-0.7
Townsend deprivation index at recruitment	0.2	0.3	0.3	0.5	0.6
Fed-up feelings	0.2	0.3	0.4	0.4	-0.6
Stomach or abdominal pain in last month	0.2	0.3	0.6	-0.8	0.1
Nervous feelings	0.2	0.3	0.6	0.8	-0.1
Hearing difficulty/problems with background noise	0.2	0.3	0.6	-0.2	-0.8
Qualifications: None of the above	0.2	0.5	0.5	0.7	0.7
Falls in the last year	0.2	0.3	0.3	0.6	-0.5
Asthma	0.2	0.3	0.6	-0.1	0.8
Medication: Cholesterol lowering	0.2	0.3	0.6	-0.2	-0.8
Hair/balding pattern: Pattern 4	0.2	0.4	0.6	-0.5	0.8
High blood pressure (siblings)	0.2	0.2	0.2	0.4	0.5
Body fat percentage	0.2	0.8	1.2	-0.7	-1.1
Exposure to tobacco smoke outside home	0.2	0.2	0.4	0.2	-0.6
Medication: Omeprazole	0.2	0.2	0.3	0.5	0.3
Medication: Seretide 50 evohaler	0.2	0.2	0.4	0.2	0.6
Overall health rating	0.2	0.5	0.7	0.9	0.5
Long-standing illness, disability or infirmity	0.2	0.2	0.4	-0.3	-0.6
Eye problems/disorders: Cataract	0.2	0.2	0.4	-0.7	0.2
Mineral and other dietary supplements	0.2	0.3	0.4	-0.5	-0.6
Breast cancer (self-reported)	0.2	0.3	0.5	0.1	0.7
Osteoarthritis (self-reported)	0.2	0.2	0.4	-0.1	-0.6
Miserableness	0.2	0.3	0.5	0.0	-0.7
Ever taken oral contraceptive pill	0.2	0.3	0.5	0.2	-0.7
Illnesses of father: High blood pressure	0.2	0.2	0.4	0.7	0.0
Age started oral contraceptive pill	0.2	0.2	0.5	-0.1	-0.7
Ever depressed for a whole week	0.2	0.2	0.3	0.4	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.4	-0.5	-0.6
Neuroticism (Nagel 2018)	0.1	0.3	0.6	0.8	0.0
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	-0.5	0.0
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	0.0	0.4
Ovarian Cancer	0.1	0.1	0.2	-0.2	0.4
Blood Red Count	0.1	1.2	1.9	1.4	0.7
Lung FVC	0.1	0.7	1.4	-1.2	-0.2
Angina	0.1	0.1	0.1	0.3	-0.3
Vitamin and mineral supplements	0.1	0.1	0.2	-0.4	-0.2
Age when periods started (menarche)	0.1	0.2	0.3	0.5	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.4	-0.6	0.0
Qualifications: CSEs or equivalent	0.1	0.1	0.1	-0.4	0.1
High blood pressure	0.1	0.1	0.2	0.4	0.4
Multivitamins +/- minerals	0.1	0.1	0.1	0.3	0.3
Medication: Atenolol	0.1	0.1	0.2	0.1	-0.4
High blood pressure (mother)	0.1	0.1	0.3	0.5	0.1
Had other major operations	0.1	0.1	0.1	0.0	-0.4
Financial difficulties in last 2 years	0.1	0.1	0.3	-0.0	0.5
Mouth/teeth dental problems	0.1	0.1	0.2	-0.2	0.5
Heart attack	0.1	0.2	0.2	-0.4	-0.5
Lung cancer (father)	0.1	0.1	0.2	-0.5	0.1
Wheeze or whistling in the chest in last year	0.1	0.1	0.1	-0.3	0.4
Age at first live birth	0.1	0.2	0.4	0.1	0.6
Emphysema/chronic bronchitis	0.1	0.1	0.1	0.3	0.1
Angina (self-reported)	0.1	0.2	0.3	0.6	-0.2
Heart disease (mother)	0.1	0.1	0.1	-0.3	-0.3
Supplements: Vitamin C	0.1	0.1	0.2	0.4	-0.3
Knee pain experienced in last month	0.1	0.1	0.1	0.2	0.4
Illnesses of father: Heart disease	0.1	0.1	0.2	-0.2	-0.5
Average weekly red wine intake	0.1	0.1	0.2	-0.2	-0.5
Asthma (self-reported)	0.1	0.3	0.4	-0.6	0.4
Financial situation satisfaction	0.1	0.2	0.3	-0.2	-0.5
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	-0.1	0.4
Medication: Blood pressure	0.1	0.2	0.3	0.1	-0.6
Number of operations (self-reported)	0.1	0.1	0.2	-0.4	0.1
Unable to work because of sickness or disability	0.1	0.2	0.3	-0.2	-0.6
Worry (Nagel 2018)	0.0	0.1	0.1	0.4	-0.2
Rheumatoid Arthritis	0.0	0.0	0.0	0.1	0.1
Triglycerides	0.0	0.0	0.0	-0.0	0.1
Blood Platelet Count	0.0	0.4	0.7	-0.2	-0.8
Cardiovascular Disease	0.0	0.1	0.2	-0.2	-0.4
Hair Pigment	0.0	0.3	0.6	-0.0	-0.7
Systolic blood pressure, automated reading	0.0	0.0	0.0	0.0	0.2
Diabetes (mother)	0.0	0.0	0.0	0.1	-0.2
Supplements: Glucosamine	0.0	0.0	0.0	-0.0	0.1
Alcohol usually taken with meals	0.0	0.1	0.1	0.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.1	0.1	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	-0.1	0.4
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.0	-0.1	-0.2
Alcohol intake versus 10 years previously	0.0	0.0	0.0	-0.1	-0.1
Pulse wave Arterial Stiffness index	0.0	0.0	0.0	0.2	0.1
Leg fat percentage (right)	0.0	0.0	0.1	-0.3	-0.2
Hypertension (Self-reported)	0.0	0.0	0.1	0.2	0.2
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.1	-0.2	0.4
Osteoporosis (self-reported)	0.0	0.0	0.1	0.3	0.0
Number of self-reported non-cancer illnesses	0.0	0.0	0.0	0.1	0.1
Guilty feelings	0.0	0.0	0.1	0.0	0.3
Pain type(s) experienced in last month: Hip pain	0.0	0.1	0.1	0.2	0.3
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	-0.2	-0.0
Leg fat percentage (left)	0.0	0.0	0.0	-0.0	0.2
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.2	-0.4	-0.2
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	-0.0	-0.1
Alcohol drinker status: Previous	0.0	0.0	0.1	0.0	0.3

Hub : Genes

NDUFB8

Models

Trait associations