TWAS hub - BAG3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.1330	0.0480	1.8e-03	0.033	NA	0.007	NA	0.025	1.6e-03	NA	8.9e-02	NA	5.1e-03
2	GTEx	Esophagus Gastroesophageal Junction	0.4390	0.0910	1.4e-05	0.325	NA	0.175	NA	0.324	1.9e-12	NA	6.5e-07	NA	2.1e-12
3	NTR	Blood	0.0527	0.0145	4.5e-08	0.021	0.026	0.032	0.028	0.027	2.3e-07	6.2e-09	1.0e-10	1.7e-09	2.8e-09
4	ROSMAP	Brain Pre-frontal Cortex	0.1000	0.0322	5.0e-04	0.060	0.012	0.033	0.034	0.044	3.5e-08	8.8e-03	3.7e-05	2.6e-05	1.9e-06
5	YFS	Blood	0.0387	0.0133	4.5e-05	0.031	0.014	0.027	0.024	0.030	2.2e-10	1.1e-05	2.5e-09	1.8e-08	4.8e-10
6	TCGA	Breast Invasive Carcinoma	0.0217	0.0096	4.6e-04	0.005	0.012	0.005	NA	0.003	2.7e-02	1.1e-03	3.1e-02	NA	6.0e-02
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0406	0.0183	4.9e-04	0.045	0.034	0.032	NA	0.032	7.8e-06	9.2e-05	1.3e-04	NA	1.5e-04
8	TCGA	Lung Squamous Cell Carcinoma	0.0435	0.0245	5.6e-03	0.021	0.004	0.002	NA	0.008	1.5e-03	1.1e-01	1.7e-01	NA	3.9e-02
9	TCGA	Prostate Adenocarcinoma	0.0390	0.0206	3.8e-03	0.027	0.028	0.024	NA	0.028	6.8e-04	5.7e-04	1.3e-03	NA	6.0e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Heart attack/myocardial infarction (self-reported)	3.6	4.7	8.8	2.8	-0.1	-0.2	2.8	-3.0	0.3	1.9	2.9	2.4
Supplements: Glucosamine	3.4	4.4	9.9	-2.9	-1.2	1.4	-2.7	3.1	-0.3	-0.7	-2.6	-1.9
Heart attack	3.3	4.2	8.2	2.5	-0.2	-0.3	2.7	-2.9	0.6	1.9	2.7	2.2
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	6.2	1.8	-1.2	0.4	2.4	-2.1	-0.3	2.2	2.5	1.8
Medication: Atorvastatin	3.0	3.7	7.0	2.4	-1.4	-0.1	2.6	-2.6	-0.0	1.6	2.4	1.8
Sensitivity / hurt feelings	2.9	4.9	9.4	-2.6	-1.6	-0.4	-2.2	2.2	2.1	-1.5	-3.1	-2.9
HbA1C	2.8	3.1	10.4	-1.4	-0.8	-2.2	-0.5	0.3	3.2	-0.3	-1.2	-2.8
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.5	9.5	3.1	1.1	1.2	2.6	-2.4	-1.8	2.0	2.9	3.0
Supplements: Calcium	2.7	2.9	5.7	1.7	0.8	0.8	1.9	-1.7	-0.7	2.1	2.4	2.3
Had other major operations	2.5	3.0	7.6	2.8	0.8	0.6	1.8	-2.0	-1.1	1.3	2.3	1.9
Vascular/heart problems diagnosed by doctor	2.5	6.9	16.2	-2.8	0.4	-0.3	-3.1	2.8	2.9	-1.3	-3.1	-4.0
Alzheimer’s Disease (in father)	2.4	2.6	6.4	1.6	-0.1	-0.5	1.5	-1.7	-2.0	0.9	2.5	2.2
Eye problems/disorders: Glaucoma	2.4	2.8	6.6	2.0	-1.0	0.4	2.2	-1.9	-0.8	0.7	2.1	2.6
Medication: Blood pressure	2.3	4.0	8.6	2.6	-0.8	-0.6	2.3	-2.1	-1.6	1.5	2.3	2.9
Diabetes (father)	2.2	2.7	5.1	2.2	1.5	0.8	2.0	-1.8	-0.9	2.0	1.9	0.8
Diabetes (mother)	2.2	2.8	5.4	1.9	-0.7	0.6	2.3	-2.3	-1.2	0.8	2.1	1.8
Age when periods started (menarche)	2.2	5.3	13.3	2.7	-3.6	-0.4	2.8	-2.2	-0.1	1.6	2.3	2.6
Pulse rate	2.2	3.7	6.4	2.1	1.1	1.3	2.2	-1.9	-1.8	1.7	2.2	2.5
Medication: Lansoprazole	2.2	2.5	5.0	-2.0	0.4	-1.5	-1.6	1.6	0.9	-2.2	-2.0	-1.1
Heart disease (mother)	2.2	2.7	4.8	1.7	1.4	-0.4	2.2	-1.9	-0.2	2.1	1.8	1.8
High blood pressure	2.1	5.7	14.0	2.5	-0.6	0.6	2.6	-2.3	-3.2	1.2	2.7	3.7
Medication: Lisinopril	2.1	2.7	6.3	2.1	-1.6	-0.7	2.1	-2.5	0.6	0.6	1.5	1.8
Medication: Ramipril	2.0	2.5	3.8	1.9	1.1	0.9	1.9	-1.5	-1.5	1.9	1.7	1.4
Medication for cholesterol, blood pressure or diabetes	2.0	3.3	5.4	-2.3	0.6	0.4	-2.3	1.7	1.5	-2.0	-2.0	-2.3
Supplements: Fish oil (including cod liver oil)	2.0	2.6	6.5	1.3	-1.3	1.7	0.9	-0.3	-2.3	2.5	1.3	1.8
Breast Cancer	1.9	4.5	14.8	-2.9	-0.8	0.5	-2.0	1.5	3.8	-0.3	-2.1	-2.3
Cardiovascular Disease	1.9	6.4	11.3	2.8	-0.5	-0.0	3.4	-3.1	-1.8	2.2	3.1	3.3
Fluid intelligence score	1.9	4.0	11.5	2.1	-1.5	0.4	1.9	-2.2	0.6	3.4	2.4	1.7
Number of children fathered	1.9	2.1	3.8	-2.0	0.4	0.2	-1.9	1.9	0.5	-1.5	-1.9	-1.2
Medication: Aspirin	1.9	2.5	6.0	1.6	-2.5	-0.8	2.1	-1.5	-0.7	0.9	1.6	1.6
Medication: Cholesterol lowering	1.8	2.9	4.9	2.2	-0.8	0.4	2.0	-1.3	-1.7	2.2	1.8	1.9
Ever had prostate specific antigen (PSA) test	1.8	2.0	4.7	1.1	-0.3	2.0	0.6	-0.3	-2.2	1.5	1.4	1.9
Irritable Bowel Disease (IBD)	1.7	4.0	8.7	2.2	1.4	-1.4	2.3	-3.0	1.7	2.0	2.0	1.6
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	7.3	-1.7	-2.7	2.1	-1.1	1.9	-0.1	1.6	-0.9	-0.4
Hypertension (Self-reported)	1.7	4.8	10.6	2.2	-0.3	0.7	2.3	-2.1	-3.1	1.2	2.3	3.3
Number of self-reported non-cancer illnesses	1.7	2.9	5.2	1.5	-1.1	1.9	2.1	-1.6	-0.2	2.3	1.7	1.9
Age started oral contraceptive pill	1.7	2.2	6.2	0.8	-0.6	-2.5	0.9	-2.0	2.3	-1.2	0.4	-0.8
Lung FEV1/FVC ratio	1.6	8.2	17.3	3.2	-1.1	1.9	2.8	-3.1	-3.2	0.9	4.2	3.6
Medication: Co-codamol	1.6	1.9	3.8	-1.7	-1.9	1.3	-1.1	1.2	1.0	-0.2	-1.3	-1.8
Medication: Atenolol	1.6	2.0	5.9	1.2	-0.1	-1.7	1.6	-2.4	1.3	-0.9	1.0	1.4
Pulse wave reflection index	1.6	2.0	4.2	-1.6	-0.8	0.7	-1.7	2.0	0.4	0.4	-1.6	-2.0
Medication: Amlodipine	1.6	2.2	6.0	1.2	-2.4	-0.8	2.0	-1.6	-0.6	-0.1	1.4	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	3.6	-1.6	1.1	-0.6	-1.6	1.9	0.3	-1.0	-1.9	-1.3
Medication for cholesterol	1.5	2.3	4.8	-1.2	1.6	-0.6	-1.9	1.6	1.5	-0.5	-1.8	-2.2
Illnesses of father: None of the above (group 1)	1.5	1.8	3.6	-1.2	-1.1	-1.0	-1.4	1.7	0.1	-1.9	-1.6	-1.1
Hand grip strength (left)	1.4	3.6	13.1	-1.2	3.6	1.4	-1.6	2.0	-2.9	0.2	-0.7	0.3
Ever used hormone-replacement therapy (HRT)	1.4	1.8	6.4	-0.9	-2.5	-0.1	-0.8	0.5	2.1	-0.2	-1.2	-1.5
Leg fat-free mass (left)	1.4	7.6	21.6	2.0	4.7	2.4	1.4	-1.6	-4.2	-0.0	2.4	3.0
Leg predicted mass (left)	1.4	7.2	21.8	1.9	4.7	2.4	1.3	-1.4	-4.1	-0.2	2.2	2.9
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	3.5	-1.7	0.7	-1.9	-1.2	1.1	0.1	-1.4	-1.4	-1.0
Pulse rate, automated reading	1.4	4.5	7.1	2.6	2.0	0.3	2.7	-2.6	-2.1	0.2	2.1	2.5
Leg fat-free mass (right)	1.4	7.6	20.6	1.9	4.5	2.4	1.4	-1.4	-4.4	-0.1	2.3	3.1
Medication: Aspirin	1.4	1.9	3.7	1.5	-1.7	-0.6	1.9	-1.3	-0.7	0.9	1.4	1.6
Leg predicted mass (right)	1.4	7.5	20.9	1.9	4.6	2.5	1.4	-1.4	-4.3	-0.1	2.2	3.0
Ulcerative Colitis (UC)	1.3	2.4	5.2	1.4	0.6	-0.5	1.6	-2.3	1.4	1.8	1.8	1.7
Type 2 Diabetes (T2D) (2018)	1.3	2.4	6.4	1.1	0.4	1.0	1.7	-0.6	-2.3	1.4	1.4	2.5
Current tobacco smoking	1.3	2.1	8.8	-0.8	-3.0	-1.1	-0.6	1.1	1.5	-0.1	-1.3	-1.6
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	5.3	-1.6	2.3	-0.8	-1.1	1.3	0.7	-0.0	-1.4	-0.7
Lung cancer (father)	1.3	1.5	4.2	-1.1	0.8	0.0	-1.7	2.1	-1.0	-1.1	-1.6	-0.3
Loud music exposure frequency	1.3	1.4	3.5	1.1	0.3	-0.1	1.8	-1.5	-0.2	-0.2	1.5	1.9
Age at last live birth	1.3	1.8	3.9	1.5	0.4	-2.0	1.1	-1.0	-1.3	-1.5	0.8	1.8
Commuting to job workplace: Car/motor vehicle	1.3	1.5	4.5	0.9	0.4	2.1	0.5	-1.1	-1.0	0.4	1.4	1.8
Height	1.2	22.7	48.9	5.8	7.0	3.1	4.5	-6.4	-1.9	0.6	5.3	4.4
Medication: Metformin	1.2	1.7	3.6	1.2	-1.0	1.0	1.9	-0.8	-1.2	1.4	1.3	1.6
Number of incorrect matches in round	1.2	2.1	3.5	-1.9	-1.5	-0.1	-1.6	1.5	1.1	-1.8	-1.7	-0.7
Hair/balding pattern: Pattern 2	1.2	1.5	6.3	0.5	1.1	-2.5	0.8	-1.4	1.5	-1.0	0.3	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	7.9	2.1	1.5	1.3	1.7	-1.7	-2.8	-0.3	2.2	2.8
Glaucoma (self-reported)	1.2	1.4	2.7	1.4	-1.4	0.4	1.2	-1.1	-1.0	0.6	1.2	1.6
Qualifications: College or University degree	1.2	3.9	9.9	1.8	1.4	2.1	1.1	-1.0	-3.1	1.9	2.3	2.0
Angina (self-reported)	1.2	1.6	3.7	1.1	1.3	-1.5	1.7	-1.9	1.3	-0.4	1.0	0.5
Family relationship satisfaction	1.2	1.5	9.1	0.1	-3.0	1.6	-0.1	0.3	-0.0	0.9	0.4	-0.6
Long-standing illness, disability or infirmity	1.2	1.9	5.9	1.5	-1.1	-0.0	2.4	-1.7	0.5	1.0	1.2	1.4
Medication: Blood pressure	1.2	2.4	5.5	1.3	-1.2	-0.4	1.9	-1.8	-1.7	0.0	1.8	2.3
Mean Putamen Volume	1.1	1.2	4.5	-1.1	-0.0	1.0	-1.4	1.3	-2.1	-0.5	-0.7	0.3
Ulcerative Colitis	1.1	1.6	4.1	0.6	1.5	-1.1	0.9	-2.0	1.7	0.4	1.0	1.0
Angina	1.1	1.4	3.7	1.0	0.8	-1.3	1.6	-1.9	1.4	-0.2	1.0	0.4
Hand grip strength (right)	1.1	3.0	15.4	-0.6	3.9	1.2	-0.9	1.4	-2.5	0.3	-0.4	0.6
Sitting height	1.1	8.0	24.0	3.0	4.9	0.8	2.6	-2.7	-2.5	0.1	2.8	3.1
Impedance of arm (right)	1.1	5.2	12.2	3.2	-0.4	0.1	2.9	-3.5	1.2	1.8	3.0	1.6
Time employed in main current job	1.1	1.3	8.7	0.4	2.9	-1.3	0.3	0.1	0.6	0.1	-0.5	-0.1
Father’s age at death	1.1	1.5	4.4	-1.1	-1.4	0.7	-1.6	1.2	0.8	2.1	-0.7	-0.6
Standing height	1.1	11.0	35.9	3.6	6.0	1.3	2.9	-3.8	-1.6	0.2	3.5	3.3
Age at first live birth	1.1	1.9	2.9	1.7	1.3	-1.6	1.5	-1.3	-1.2	-0.5	1.3	1.7
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.7	0.9	1.5	-0.6	1.9	-1.4	-0.4	1.0	1.0	1.0
Supplements: Vitamin C	1.1	1.3	2.7	-1.3	-0.8	1.6	-1.2	1.6	0.7	0.6	-0.9	-1.0
Bipolar Disorder (2011)	1.0	1.0	2.0	1.1	-0.8	0.6	1.3	-1.4	0.8	1.2	0.9	0.6
Primary Biliary Cirrhosis	1.0	1.4	2.9	-1.3	1.1	-0.6	-1.1	1.0	1.1	-0.8	-1.6	-1.7
Qualifications: CSEs or equivalent	1.0	1.3	2.8	-1.6	0.1	-0.6	-1.2	1.4	-0.1	-1.7	-1.4	-0.8
Impedance of leg (left)	1.0	4.8	20.7	-1.3	-2.5	-1.8	-0.8	0.7	4.6	0.6	-1.6	-2.6
Impedance of arm (left)	1.0	4.6	10.8	3.0	-0.6	0.4	2.8	-3.3	1.0	1.8	2.8	1.2
Breastfed as a baby	1.0	1.3	2.7	-1.4	-0.2	0.3	-1.5	1.5	-0.1	-1.5	-1.6	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	4.5	-1.3	-1.2	-1.3	-0.9	0.7	2.1	-1.0	-1.5	-0.6
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	3.7	1.5	0.6	-0.7	1.7	-1.9	0.7	1.5	1.6	1.3
Pulse wave peak to peak time	1.0	1.2	2.3	1.4	0.5	-0.8	1.1	-1.4	-0.5	-0.3	1.5	1.3
Health satisfaction	1.0	1.3	3.9	1.4	-2.0	-0.8	1.4	-1.3	0.1	-0.3	0.9	0.8
Eye problems/disorders: None of the above	1.0	1.1	3.5	-0.7	1.8	0.4	-1.0	0.8	0.7	0.0	-0.7	-1.9
Loneliness, isolation	1.0	1.4	7.2	-0.4	-0.1	-2.7	-0.0	0.2	1.8	-1.2	-0.8	-0.2
Breast cancer (self-reported)	1.0	1.2	2.9	1.7	-1.0	-0.6	1.3	-1.6	1.0	0.9	0.8	-0.2
Medication: Bendroflumethiazide	1.0	1.5	3.4	1.4	-1.2	-0.7	1.0	-1.1	-1.8	0.5	1.5	1.0
Fractured/broken bones in last 5 years	1.0	1.3	4.9	1.2	-2.2	0.7	1.0	-1.3	0.7	1.0	1.2	-0.3
Diastolic blood pressure, automated reading	1.0	3.1	8.6	1.2	2.1	1.8	1.4	-1.0	-2.9	1.4	1.5	1.9
Schizophrenia vs Biploar Disorder	0.9	1.2	2.8	-1.5	0.1	-0.2	-1.3	1.7	-1.1	-1.1	-1.1	-0.3
Crohns Disease (2017)	0.9	1.9	3.6	1.7	1.6	-0.9	1.7	-1.9	1.0	1.4	1.1	0.7
Smoking Status	0.9	2.2	11.2	-0.4	-3.4	-1.4	-0.5	0.6	1.6	-0.9	-1.3	-1.0
Chronotype (morning person)	0.9	2.1	3.8	2.0	-0.5	0.8	1.6	-1.5	-1.6	0.9	1.9	1.5
Average weekly spirits intake	0.9	1.2	1.7	1.3	-1.1	-1.0	1.2	-1.3	1.2	0.7	1.1	0.8
Severe depression (siblings)	0.9	1.0	4.6	0.1	-1.2	-2.2	0.9	-0.7	0.9	-0.7	0.2	0.6
Townsend deprivation index at recruitment	0.9	1.2	3.2	1.3	-0.1	-0.2	1.6	-1.8	0.1	0.7	1.6	0.5
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	5.1	-0.8	-0.9	1.1	-0.4	0.8	0.0	2.3	-0.4	-0.0
Financial difficulties in last 2 years	0.9	1.3	7.8	-0.6	-2.8	0.8	-0.4	1.1	-0.1	0.3	-0.7	-0.8
Weight	0.9	4.6	14.6	1.4	3.8	2.1	1.1	-1.1	-3.1	0.5	1.8	2.4
Noisy workplace	0.9	1.1	7.0	-0.2	-2.6	1.2	-0.5	0.7	-0.5	-0.3	-0.3	-0.2
Qualifications: A levels/AS levels or equivalent	0.9	1.9	4.1	1.2	-0.1	1.5	0.7	-0.9	-1.8	1.8	2.0	1.3
Medication: Ventolin 100micrograms inhaler	0.9	1.2	4.4	0.0	-0.0	-1.7	0.6	-0.8	2.1	-1.3	-0.3	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	3.8	-0.9	-1.3	0.4	-0.9	1.3	-1.9	-0.0	-0.2	0.3
Neck or shoulder pain in last month	0.9	1.3	7.6	0.2	-2.8	1.0	0.5	0.6	-1.3	0.6	0.0	0.8
Illnesses of father: Heart disease	0.9	1.2	2.3	0.9	0.9	1.5	0.7	-1.5	0.2	1.0	1.4	1.2
Whole body fat-free mass	0.9	5.1	23.3	0.9	4.8	1.9	0.4	-0.6	-3.4	-0.7	1.2	2.0
Average weekly red wine intake	0.9	1.3	5.6	-0.8	0.3	1.4	-1.0	1.2	-2.4	0.8	-0.0	0.3
Smoking status: Current	0.9	1.5	6.6	-0.5	-2.6	-0.9	-0.4	0.7	1.4	0.0	-0.9	-1.3
Whole body water mass	0.9	5.2	23.2	0.9	4.8	1.9	0.5	-0.6	-3.5	-0.8	1.2	2.2
Tinnitus: Yes, now most or all of the time	0.9	1.1	3.8	0.7	-0.5	1.9	0.5	0.1	-2.0	0.4	0.8	0.7
Basal metabolic rate	0.9	5.1	21.3	1.1	4.6	2.0	0.6	-0.8	-3.4	-0.4	1.4	2.2
Average weekly beer plus cider intake	0.9	1.3	3.8	0.4	-2.0	-1.6	0.8	-0.3	1.8	-0.2	-0.8	-0.9
Depressed Affect (Nagel 2018)	0.8	1.7	6.4	-1.6	-2.5	0.3	-0.7	1.2	1.2	-0.0	-1.1	-1.2
Schizophrenia (2018)	0.8	1.7	3.8	1.4	0.3	-0.8	1.9	-0.8	-1.8	-0.1	1.4	1.9
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.4	0.3	1.3	1.5	0.2	-0.2	-1.3	1.3	0.8	-0.3
Hypothyroidism (self reported)	0.8	1.9	4.1	1.5	1.1	-0.2	1.7	-1.6	-0.7	1.2	1.7	2.0
Relative age of first facial hair	0.8	1.6	2.7	1.3	-1.6	-1.0	1.5	-1.3	0.6	1.4	1.1	1.1
Impedance of leg (right)	0.8	3.6	19.2	-0.9	-1.8	-1.8	-0.5	0.2	4.4	0.7	-1.1	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	3.5	0.6	-1.5	0.6	1.1	-0.6	-0.5	0.4	1.1	1.9
Hayfever, allergic rhinitis or eczema	0.8	1.7	6.0	1.1	-0.3	2.5	1.2	-1.2	0.1	1.7	1.4	0.3
Past tobacco smoking	0.8	1.6	5.8	-0.8	1.7	2.4	-0.9	1.1	-1.1	1.1	-0.3	-0.2
Alcohol usually taken with meals	0.8	1.3	6.6	-0.3	0.0	2.6	-0.9	0.7	-1.5	1.0	0.2	0.7
Qualifications: None of the above	0.8	1.8	6.2	-0.3	-1.0	-2.2	0.1	-0.6	2.5	-1.4	-0.7	-1.1
Illnesses of siblings	0.8	1.1	2.9	-1.0	0.6	0.3	-1.3	1.6	0.4	0.2	-1.1	-1.7
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	9.1	1.3	1.6	1.6	0.8	-0.6	-3.0	-0.5	1.3	2.3
Trunk predicted mass	0.8	4.3	23.8	0.4	4.9	1.7	-0.1	-0.2	-2.9	-0.9	0.6	1.5
Blood clot in the leg (DVT)	0.8	1.0	2.0	1.3	-1.3	-1.1	1.1	-1.4	-0.1	0.1	1.1	0.4
Gout (self-reported)	0.8	1.1	3.3	-0.8	1.0	0.0	-0.7	0.4	1.8	0.2	-1.1	-1.8
Birth weight	0.8	1.8	5.7	-1.5	2.4	0.7	-1.7	0.9	1.4	-0.6	-1.0	-0.8
Medication: Omeprazole	0.8	1.0	2.1	1.1	1.4	-0.3	1.2	-1.4	-0.0	0.1	1.1	0.7
Smoking status: Previous	0.8	1.3	3.4	1.0	-1.4	-1.8	1.1	-1.3	0.7	-0.8	0.6	0.7
Diabetes diagnosed by doctor	0.8	1.3	3.0	0.8	-0.1	0.8	1.7	-0.3	-1.7	0.8	0.9	1.7
Eye problems/disorders: Cataract	0.8	1.0	2.7	-0.5	-1.6	-1.0	-0.8	1.0	-0.7	-1.2	-0.8	0.6
Back pain experienced in last month	0.8	1.1	4.6	0.9	-2.1	-0.4	1.7	-0.8	-0.4	0.6	0.6	0.4
Wears glasses or contact lenses	0.8	0.9	2.5	1.0	-0.4	-1.6	0.6	-1.3	1.3	-0.4	0.5	-0.4
Illnesses of father: High blood pressure	0.8	1.0	4.6	0.8	2.1	-0.4	0.5	-0.2	-0.6	1.5	0.3	0.3
Bipolar Disorder or Schizophrenia	0.7	1.7	4.6	1.6	0.3	-0.4	2.2	-1.3	-1.3	0.5	1.5	1.5
Major Depression (MDD)	0.7	0.8	5.0	-0.0	0.1	-2.2	0.4	-0.2	1.3	-0.3	-0.4	0.3
Verbal and Numeric Reasoning (VNR)	0.7	1.8	6.3	1.3	-0.8	0.6	0.9	-1.5	0.5	2.5	1.8	0.7
HDL Cholesterol	0.7	1.2	2.1	1.3	-1.3	-0.9	1.2	-1.4	0.5	0.9	1.1	0.9
Lupus	0.7	1.0	4.7	0.6	-0.2	-2.2	0.7	-0.9	-0.5	-0.5	0.6	1.3
Respiratory disease	0.7	1.5	4.7	-1.1	0.2	0.3	-1.2	1.3	1.2	-0.9	-1.4	-2.2
Ever had hysterectomy (womb removed)	0.7	0.8	1.7	0.8	1.3	-0.5	0.9	-1.0	-0.8	0.1	0.9	1.3
Vitamin and mineral supplements	0.7	1.0	5.2	0.4	0.6	-2.3	0.7	-1.0	-0.0	-1.3	0.1	-0.0
Relative age voice broke	0.7	1.1	2.7	1.3	-1.7	-0.1	1.2	-1.0	0.5	1.0	0.9	1.0
Neuroticism score	0.7	1.5	3.1	-1.7	-1.3	-1.1	-0.5	0.8	1.8	-1.1	-1.2	-0.9
Trunk fat-free mass	0.7	4.2	23.6	0.5	4.9	1.7	-0.0	-0.3	-2.8	-1.0	0.6	1.5
Hip circumference	0.7	2.9	7.9	1.0	2.5	2.0	0.6	-0.4	-2.8	0.6	1.3	2.1
Hair/balding pattern: Pattern 3	0.7	1.1	3.4	0.7	0.7	1.6	0.1	-0.0	-1.9	1.5	0.7	0.4
Pulse wave Arterial Stiffness index	0.7	0.8	1.8	-1.2	-0.1	0.7	-0.8	1.1	0.6	0.3	-1.3	-1.1
Arm fat mass (right)	0.7	2.7	7.2	1.0	1.9	2.2	0.8	-0.6	-2.7	0.9	1.4	1.8
Medication: Paracetamol	0.7	1.2	6.2	-0.2	0.0	-1.5	0.7	-0.5	2.5	-1.1	-0.3	-0.6
Forced vital capacity (FVC), Best measure	0.7	2.7	5.3	1.8	2.0	0.7	1.4	-1.5	-1.9	-0.2	1.7	2.3
Mean time to correctly identify matches	0.7	1.3	3.5	-1.6	-0.6	0.0	-0.8	1.0	1.9	-0.4	-1.4	-1.1
Number of full sisters	0.7	0.9	4.1	-1.0	0.0	-0.3	-0.5	0.5	2.0	0.1	-1.0	-1.0
Chest pain or discomfort	0.7	0.9	3.3	-0.1	-1.0	-0.5	0.6	-0.6	1.8	0.7	-0.3	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	4.6	0.3	-2.1	1.2	-0.4	0.2	-0.0	0.3	0.1	-0.4
Friendships satisfaction	0.7	0.9	6.4	0.2	-2.5	-0.1	-0.1	-0.2	0.7	0.0	-0.1	-1.1
Miserableness	0.7	1.2	5.2	-1.1	-2.3	-0.3	-0.7	0.6	1.0	-0.1	-0.9	-1.4
Hearing aid user	0.7	0.8	3.4	-0.5	-0.4	1.8	0.2	0.1	-1.7	-0.2	0.5	0.3
Financial situation satisfaction	0.7	0.8	3.8	-0.1	0.1	1.4	-0.4	1.2	-2.0	-0.0	-0.3	0.2
Risk taking	0.7	1.0	3.2	0.5	1.2	1.1	0.8	0.1	-1.4	0.1	0.8	1.8
Ever depressed for a whole week	0.7	0.8	2.0	-1.0	-1.4	0.5	-1.0	1.0	-0.3	-1.1	-0.8	-0.6
Unable to work because of sickness or disability	0.7	1.0	4.0	1.0	0.2	0.5	1.2	-0.4	-2.0	0.1	0.8	1.0
Neuroticism (Nagel 2018)	0.6	1.3	7.1	-0.9	-2.7	-0.2	-0.0	0.6	1.7	0.4	-0.7	-0.6
Alzheimer’s Disease (including proxy)	0.6	0.9	2.8	0.2	-0.8	-1.7	0.6	-1.2	1.4	-0.2	0.7	0.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.1	-1.3	-1.5	0.9	-0.6	1.1	0.2	-0.0	-0.7	-0.0
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.2	0.7	1.0	0.0	1.4	-1.1	1.5	0.4	0.5	-0.4
Stomach or abdominal pain in last month	0.6	0.8	3.7	-0.3	-1.9	-0.7	0.3	0.1	0.2	-1.3	-0.2	0.9
Trunk fat mass	0.6	2.5	5.2	1.2	2.3	2.0	1.0	-1.1	-1.9	0.9	1.6	1.6
Hearing difficulty/problems with background noise	0.6	1.0	3.1	-1.5	-0.3	0.0	-0.9	1.0	0.3	-1.8	-1.1	-0.7
Mouth/teeth dental problems	0.6	1.0	4.8	-0.1	-0.1	-1.4	-0.8	-0.3	2.2	-0.7	-0.1	-0.8
Allergy	0.6	1.3	2.2	-1.2	0.5	-1.3	-1.5	1.5	-0.3	-1.1	-1.5	-0.5
Prospective memory result	0.6	0.8	3.1	-0.7	-1.7	1.1	-0.7	0.8	0.2	0.5	-0.5	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.5	-1.1	-0.4	0.1	-0.6	0.3	1.6	-1.1	-1.0	-0.8
Medication: Allopurinol	0.6	0.8	2.8	-0.7	0.5	0.9	-0.8	0.5	0.8	0.2	-0.9	-1.7
Whole body fat mass	0.6	2.5	5.4	1.1	1.9	2.3	0.8	-0.9	-2.1	1.3	1.5	1.7
Comparative height size at age 10	0.6	3.4	26.4	0.9	5.1	0.6	0.5	-1.0	-0.4	-0.2	1.0	0.2
Overall health rating	0.6	1.4	3.7	1.2	-1.9	-0.7	1.9	-1.2	1.3	-0.2	0.2	-0.2
Illnesses of siblings: Diabetes	0.6	0.7	2.2	0.1	-0.6	-1.5	0.7	-0.7	0.5	-1.5	-0.1	0.8
Qualifications: nursing, teaching	0.6	0.9	2.2	1.5	0.4	1.0	0.4	-1.0	-0.6	1.3	1.4	0.5
Mineral and other dietary supplements	0.6	0.8	2.5	0.3	0.8	-1.4	0.3	-0.8	1.1	-1.6	0.1	-0.2
Arm fat mass (left)	0.6	2.5	7.0	0.8	1.9	2.4	0.7	-0.5	-2.6	0.8	1.3	1.7
Guilty feelings	0.6	0.9	2.0	-1.3	-1.4	-0.1	-0.9	1.2	0.7	-0.3	-0.8	-1.0
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.1	0.7	0.2	0.5	1.0	-0.3	-1.4	0.9	1.0	1.1
Ever smoked	0.6	1.1	5.7	0.2	-2.4	-1.4	0.2	-0.1	1.0	-0.9	-0.4	-0.3
Arm fat-free mass (left)	0.6	3.2	17.6	0.4	4.2	1.2	0.1	-0.2	-2.5	-0.7	0.6	1.6
Pain experienced in last month	0.6	1.0	2.1	1.2	1.4	-1.4	0.5	-1.4	0.7	0.0	0.9	0.2
Alcohol drinker status: Previous	0.6	0.7	2.4	0.4	1.5	-0.1	1.3	-0.8	0.8	0.8	0.4	0.5
Impedance of whole body	0.6	2.9	7.2	1.7	-1.3	-0.7	1.8	-2.2	2.7	1.8	1.5	0.1
Arm predicted mass (left)	0.6	2.9	16.0	0.2	4.0	1.2	-0.1	-0.0	-2.4	-0.7	0.4	1.5
Alzheimer’s Disease (in mother)	0.5	0.6	3.2	-0.1	-0.5	-1.1	0.2	-0.9	1.8	-0.1	0.3	-0.3
Age at First Birth	0.5	0.7	1.2	1.1	-0.9	-0.7	1.1	-1.0	0.4	0.7	0.6	0.8
Rheumatoid Arthritis	0.5	0.7	1.4	-0.8	-1.2	1.0	-1.1	0.9	-0.6	0.2	-0.3	-0.9
Waist Hip Ratio (WHR)	0.5	2.1	7.2	1.1	0.6	-1.8	1.2	-2.0	2.7	0.3	0.7	0.6
Maternal smoking around birth	0.5	0.8	3.6	0.3	-0.1	-1.9	-0.1	-0.3	-0.3	-1.7	-0.3	-0.1
Serious illness, injury or assault to yourself	0.5	0.6	1.9	0.8	-1.4	-0.5	1.1	-1.0	0.2	0.3	0.8	0.5
Multivitamins +/- minerals	0.5	0.7	3.9	0.2	-0.4	2.0	-0.0	0.3	-0.5	1.1	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	5.7	0.8	2.4	-0.0	0.7	-0.5	-1.2	-0.2	0.5	0.6
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.2	0.7	1.1	0.1	1.1	-1.1	0.4	0.7	1.0	0.6
Arm fat percentage (right)	0.5	1.9	4.8	0.9	0.9	2.1	0.7	-0.5	-2.2	1.1	1.3	1.5
Alcohol intake versus 10 years previously	0.5	0.8	1.9	0.7	0.5	-1.4	0.9	-1.4	1.0	-0.5	0.7	0.2
Falls in the last year	0.5	0.7	3.6	-0.4	-1.9	-0.2	-0.1	-0.1	1.1	-1.1	-0.2	-0.4
Happiness	0.5	0.6	4.9	0.3	-2.2	-0.4	0.4	-0.2	-0.2	0.2	0.2	-0.1
Length of working week for main job	0.5	0.5	3.1	-0.2	1.8	-0.8	0.3	-0.5	0.5	-0.5	-0.0	-0.1
Exposure to tobacco smoke at home	0.5	0.5	2.0	0.1	-0.2	-1.4	0.6	-0.7	1.3	-0.3	0.0	-0.0
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.6	0.3	0.5	0.8	1.1	-0.3	-1.3	0.5	0.2	1.2
High blood pressure (siblings)	0.5	0.7	1.7	0.9	-0.4	-0.7	0.8	-1.3	-0.5	-0.6	0.6	1.3
Arm fat-free mass (right)	0.5	2.6	13.5	0.1	3.7	1.1	-0.2	0.1	-2.4	-1.1	0.2	1.1
Comparative body size at age 10	0.5	1.5	4.6	0.2	-0.8	2.1	-0.3	0.0	-1.6	2.1	1.1	0.4
Number of full brothers	0.5	0.6	2.0	-0.4	1.4	-1.4	0.5	-0.2	0.6	-0.4	-0.5	-0.3
Wheeze or whistling in the chest in last year	0.5	0.9	3.1	-0.6	-1.8	-0.9	0.2	0.5	1.4	-0.3	-0.8	-0.7
Medication for pain relief, constipation, heartburn	0.5	0.9	2.7	-0.7	0.3	1.0	-1.6	1.1	-0.7	-0.1	-0.8	-1.0
Arm predicted mass (right)	0.5	2.3	13.7	-0.1	3.7	0.9	-0.4	0.3	-2.1	-1.1	-0.0	0.8
Leg pain on walking	0.5	0.6	0.9	0.9	-0.7	-0.5	0.9	-0.7	-0.9	0.5	0.9	0.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	4.7	0.2	2.2	0.8	-0.4	0.0	-0.1	0.3	0.1	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	4.0	0.5	2.0	-0.7	0.5	-0.7	0.1	-0.3	0.2	0.1
Osteoporosis (self-reported)	0.5	0.6	1.4	0.5	-0.4	-1.2	0.4	-1.1	1.2	0.4	0.8	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	1.9	1.0	-1.0	0.6	1.0	-1.1	-1.4	-0.2	1.3	1.1
Medication: Paracetamol	0.5	0.8	3.6	-0.0	0.2	-1.2	0.9	-0.7	1.9	-1.1	-0.0	-0.3
Alcohol drinker status: Never	0.5	0.6	2.8	-0.3	-0.7	-0.1	-0.7	0.7	-1.7	-0.4	-0.2	1.0
Commuting to job workplace: Cycle	0.5	0.6	1.5	-1.2	-0.5	-0.1	-1.0	1.0	-1.0	-0.4	-0.3	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.3	1.0	-1.2	-1.1	0.8	-1.0	-0.1	-0.4	0.7	-0.1
Reaction Time	0.4	0.7	1.8	-1.1	-0.3	0.4	-0.4	0.9	1.3	0.9	-0.8	-0.7
Body Mass Index (BMI) (2010)	0.4	0.6	2.0	-0.9	0.8	-0.0	-1.4	0.7	0.2	-0.1	-0.6	-0.9
Fasting Glucose	0.4	0.4	1.6	-0.5	0.3	1.3	0.0	0.3	-0.6	1.0	0.3	-0.5
LDL Cholesterol	0.4	0.6	2.6	0.1	-0.5	0.6	0.4	-0.3	1.0	1.6	0.8	0.1
BMI	0.4	2.0	7.8	-0.5	1.9	1.7	-0.8	1.5	-2.8	0.2	-0.3	1.0
Allergy or Eczema	0.4	1.2	5.5	0.4	0.4	2.3	0.6	-0.9	0.6	1.3	0.9	-0.8
Medication for hormone replacement therapy	0.4	0.5	1.3	-0.1	-0.8	0.8	0.6	-0.4	1.2	0.7	0.1	-0.9
Trunk fat percentage	0.4	1.5	3.1	1.1	1.0	1.8	0.9	-1.1	-1.2	1.1	1.5	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	5.9	0.4	2.4	-0.1	0.4	-0.2	-0.7	-0.8	0.2	0.2
Medication: Levothyroxine sodium	0.4	0.7	1.7	0.7	1.3	-0.9	0.9	-1.0	0.3	-0.2	0.5	0.9
Waist circumference	0.4	1.6	7.7	0.8	2.8	0.8	0.7	-0.8	-1.0	0.4	0.9	1.4
Nervous feelings	0.4	0.8	2.4	0.6	0.1	-0.5	1.3	-0.8	1.5	0.9	0.6	0.9
Forced vital capacity (FVC)	0.4	1.5	4.8	1.0	1.6	0.6	0.4	-0.5	-2.2	-0.9	0.7	1.7
Medication: Simvastatin	0.4	0.6	3.3	0.6	-0.4	-0.1	0.4	-0.4	-0.6	0.4	0.7	1.8
Mouth/teeth dental problems: Dentures	0.4	0.6	1.7	-1.0	-1.3	-0.1	-0.5	0.5	-0.1	-1.1	-0.9	-0.5
Birth weight of first child	0.4	0.7	2.5	-0.2	1.5	0.9	0.1	0.7	-1.6	-0.0	-0.1	0.6
Headache pain in last month	0.4	0.8	2.2	0.5	-0.3	0.6	1.1	-0.1	-1.3	0.7	0.7	1.5
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.2	-0.1	-0.9	1.1	-0.7	0.7	-0.6	0.0	-0.5	-0.4
Exposure to tobacco smoke outside home	0.4	0.5	0.9	0.5	-0.3	0.3	1.0	-0.5	-0.9	0.2	1.0	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.0	-0.2	-1.0	1.0	-0.6	0.5	-0.7	0.9	-0.2	-0.5
Arm fat percentage (left)	0.4	1.7	4.9	0.8	0.6	2.1	0.6	-0.5	-2.2	0.9	1.2	1.2
Mood swings	0.4	0.7	3.6	-0.8	-1.9	-0.0	-0.1	0.6	0.7	-0.3	-0.9	-0.2
Commuting to job workplace: Walk	0.4	0.5	1.7	0.8	0.7	-1.3	1.0	-0.2	-0.1	0.1	0.0	0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	3.4	0.2	0.1	0.8	0.0	0.5	-1.8	0.7	0.5	0.3
Ever taken oral contraceptive pill	0.4	0.5	1.8	0.1	-1.2	1.3	0.2	0.0	-0.5	0.5	0.3	0.8
Mother’s age at death	0.4	0.6	3.8	-0.2	-1.9	0.3	-0.4	0.5	-0.7	-0.1	0.1	0.3
Commuting to job workplace: Public transport	0.4	0.4	1.2	-0.6	-1.1	-0.2	-0.3	0.9	-1.0	0.6	-0.5	0.0
Bipolar Disorder (2018)	0.3	0.5	1.2	0.9	0.2	0.3	1.0	-1.1	0.3	0.9	0.7	0.1
Worry (Nagel 2018)	0.3	0.6	3.1	-0.6	-1.2	-0.5	0.5	-0.0	1.8	-0.1	-0.3	-0.1
Neuroticism (2016)	0.3	0.5	2.4	0.7	-1.5	0.3	0.4	-0.1	0.5	1.0	0.3	0.3
Heel T-Score	0.3	2.6	5.0	2.0	0.3	-1.4	2.2	-1.9	-1.3	1.2	1.8	1.6
Systolic Blood Pressure	0.3	1.6	6.2	0.8	-0.1	0.4	1.4	-1.2	-2.5	-0.4	1.3	1.4
Systolic blood pressure, automated reading	0.3	0.8	4.2	0.2	0.9	0.1	1.0	-0.3	-2.0	0.1	0.6	1.0
Average weekly fortified wine intake	0.3	0.3	1.0	-0.2	-0.4	0.0	-0.8	0.7	-0.5	-1.0	-0.6	0.4
Fed-up feelings	0.3	0.6	2.5	-1.1	-1.6	0.3	-0.4	1.1	-0.5	-0.2	-0.5	0.0
Chronic bronchitis/emphysema (father)	0.3	0.3	2.4	-0.1	-1.5	-0.0	-0.0	-0.2	0.3	-0.4	-0.1	-0.3
Body mass index (BMI)	0.3	1.4	6.3	-0.3	1.2	1.8	-0.4	0.8	-2.5	0.5	0.2	0.9
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	0.7	-0.3	-0.9	-0.2	-0.4	0.5	0.6	-0.4	-0.7	-0.8
Pain all over the body in last month	0.3	0.3	1.1	0.1	-0.0	1.0	-0.0	0.5	-0.9	0.4	-0.2	0.4
Diabetes (self-reported)	0.3	0.5	1.9	0.6	-0.7	0.1	1.4	-0.2	-0.9	0.4	0.4	0.8
Depression (self-reported)	0.3	0.4	1.5	-0.5	-0.8	-0.3	-0.7	0.4	-0.2	-1.2	-0.5	0.3
Illnesses of mother	0.3	0.3	1.4	0.2	0.1	-0.9	-0.3	0.3	-0.5	-1.2	-0.6	-0.0
Tense / ‘highly strung’	0.3	0.5	1.9	-0.8	-0.3	-0.4	-0.5	0.7	1.4	0.2	-0.8	0.3
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.8	0.5	-0.0	0.2	0.6	-0.1	-0.2	1.3	0.6	0.4
Worry too long after embarrassment	0.3	0.6	1.9	0.5	-0.5	0.7	0.9	-0.3	-1.0	0.3	0.6	1.4
Medication: Ibuprofen	0.3	0.3	0.9	-0.8	-0.9	0.8	-0.2	0.5	-0.7	-0.0	-0.2	0.3
Alcohol intake frequency.	0.3	0.6	1.3	0.5	1.0	0.4	0.9	-1.2	-0.3	-0.1	1.0	1.0
Had major operations	0.3	0.3	1.2	0.3	0.2	-1.1	0.6	-0.7	0.6	-0.0	0.4	0.2
Knee pain experienced in last month	0.3	0.5	1.5	-1.0	-0.5	0.5	-0.5	1.2	-0.6	-0.4	-0.6	-0.0
Osteoarthritis (self-reported)	0.3	0.4	0.8	0.2	-0.9	0.4	-0.2	0.6	-0.9	0.7	-0.1	0.5
High cholesterol (Self-reported)	0.3	0.6	1.4	0.4	0.6	0.6	0.8	-0.4	-0.5	1.1	0.8	1.2
Number of operations (self-reported)	0.3	0.4	0.8	0.9	-0.9	0.6	0.4	-0.8	0.1	0.6	0.7	0.6
Myopia	0.3	0.4	1.3	0.3	-0.8	-0.7	0.6	-0.5	-0.1	-0.6	0.6	1.1
Heart disease (siblings)	0.3	0.4	1.1	0.5	-0.4	0.4	0.8	-1.0	0.9	-0.1	0.4	-0.0
Depression (Nagel 2018)	0.2	0.3	1.5	-0.4	-1.2	0.1	0.6	0.2	0.0	-0.5	-0.0	0.8
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.9	-1.2	-0.4	0.7	-1.4	1.1	-0.1	0.4	-0.7	-0.3
Ovarian Cancer	0.2	0.3	1.3	-0.3	0.3	0.2	-0.4	0.2	0.5	-1.2	-0.5	-0.7
Schizophrenia (2014)	0.2	0.5	1.0	0.5	0.4	-0.9	1.0	-0.4	-1.0	-0.4	0.6	0.9
Triglycerides	0.2	0.3	0.8	-0.3	0.9	0.9	-0.3	0.4	-0.6	-0.1	0.1	0.3
Blood Eosinophil Count	0.2	1.3	6.2	0.3	1.1	-0.8	0.3	-0.7	1.5	-2.5	-0.0	-0.9
Blood White Count	0.2	1.3	3.3	-0.8	-0.6	-0.1	-1.2	1.6	-0.0	-0.3	-1.8	-1.8
Lung FVC	0.2	0.9	2.9	0.7	-1.7	-0.3	0.6	-0.3	-1.5	-0.5	0.7	1.1
Neuroticism	0.2	0.5	1.8	-0.6	-1.3	-0.6	0.5	0.1	1.1	-0.4	-0.2	-0.5
Number of treatments/medications taken	0.2	0.3	1.0	-0.2	-0.8	-0.1	0.9	-0.7	1.0	0.4	0.1	0.0
Hearing difficulty/problems: Yes	0.2	0.3	1.2	-0.3	-1.1	0.3	0.6	-0.3	0.3	-0.7	0.1	0.1
Supplements: Zinc	0.2	0.3	1.2	-0.2	1.1	0.4	-0.0	0.3	-0.3	0.8	0.2	0.2
Pack years adult smoking proportion	0.2	0.3	0.8	0.2	-0.3	-0.6	0.7	-0.5	0.9	0.4	0.3	0.2
Taking other prescription medications	0.2	0.3	2.0	-0.1	0.1	-0.3	0.5	-0.3	1.4	0.4	-0.4	-0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.3	-0.0	-0.4	-0.5	0.3	-0.4	-0.3	-0.3	-0.0	1.1
High blood pressure (mother)	0.2	0.2	0.9	-0.3	-0.9	0.1	-0.3	0.7	-0.1	0.3	-0.5	0.3
Had menopause	0.2	0.2	0.9	0.6	-0.9	-0.2	0.3	-0.2	0.8	-0.4	0.0	-0.1
Asthma	0.2	0.4	2.0	-0.5	0.2	0.6	-0.5	0.6	0.6	-0.1	-0.6	-1.4
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.5	-0.3	-0.7	0.6	0.1	0.3	-0.7	0.5	0.0	0.2
Hair/balding pattern: Pattern 4	0.2	0.5	2.5	0.1	-0.6	0.9	0.5	0.7	-0.3	1.6	0.0	-0.1
Peak expiratory flow (PEF)	0.2	0.5	1.7	0.3	1.3	0.9	0.0	-0.0	-1.1	-0.3	0.4	0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.0	-0.4	0.8	0.4	-0.7	1.0	-0.6	0.3	-0.3	0.2
Body fat percentage	0.2	1.0	3.4	0.5	0.5	1.8	0.4	-0.4	-1.2	1.1	1.0	0.9
Shortness of breath walking on level ground	0.2	0.2	1.6	0.6	0.0	-0.0	-0.0	-0.0	-0.0	-0.5	-0.2	-1.2
Medication: Seretide 50 evohaler	0.2	0.2	0.8	-0.3	-0.3	-0.4	0.0	0.3	0.9	-0.2	-0.4	-0.8
Leg fat mass (right)	0.2	0.9	2.3	0.1	1.4	1.5	0.1	0.0	-1.5	0.6	0.5	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.7	-0.8	-0.5	0.6	-0.2	0.6	-0.6	-0.5	0.1	0.5
Asthma (self-reported)	0.2	0.4	1.7	-0.2	0.0	0.7	-0.4	0.4	0.6	0.2	-0.5	-1.3
Medication: Gliclazide	0.2	0.2	0.7	-0.1	0.5	-0.0	0.3	0.1	-0.8	-0.3	0.2	0.6
Irritability	0.2	0.4	2.5	-0.2	-1.6	-0.5	-0.4	0.6	-0.0	-0.2	-0.2	0.6
Cholesterol lowering medication	0.2	0.4	1.5	-0.1	-0.3	-0.2	0.5	-0.7	0.2	-0.5	0.7	1.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.3	0.3	1.1	-0.5	0.4	-0.6	0.1	-0.1	0.5	0.3
Basal cell carcinoma (self-reported)	0.2	0.2	0.7	-0.6	0.2	-0.0	-0.8	0.6	0.2	-0.3	-0.4	-0.4
Leg fat mass (left)	0.2	0.8	2.5	-0.0	1.2	1.6	-0.1	0.2	-1.5	0.6	0.4	0.6
Prostate Cancer	0.1	0.1	0.1	0.1	-0.2	0.4	0.4	-0.4	-0.1	0.3	0.3	0.2
Crohns Disease (2012)	0.1	0.2	1.1	0.0	-0.1	-0.5	-0.2	-0.3	1.0	0.5	-0.2	-0.5
Blood Red Count	0.1	1.3	2.9	1.2	0.7	0.5	1.7	-1.6	-0.4	0.6	1.6	1.1
Worrier / anxious feelings	0.1	0.1	0.3	-0.5	0.1	-0.4	0.0	0.2	0.2	-0.6	-0.4	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.8	-0.3	-0.5	-0.9	0.4	0.3	0.1	-0.4	-0.2	0.2
Number of live births	0.1	0.1	0.6	0.5	-0.4	0.2	-0.1	0.2	-0.1	0.0	-0.4	-0.8
Leg fat percentage (right)	0.1	0.2	0.5	-0.7	-0.2	0.5	-0.6	0.6	0.0	0.4	-0.3	-0.1
Emphysema/chronic bronchitis	0.1	0.1	0.4	-0.4	0.6	0.3	0.1	-0.2	0.4	0.2	0.1	-0.4
Migraine (self-reported)	0.1	0.2	0.7	0.0	-0.1	-0.8	0.7	-0.4	-0.1	-0.3	0.1	0.4
Suffer from ‘nerves’	0.1	0.1	0.4	-0.2	-0.6	-0.1	0.7	-0.1	0.4	0.2	0.0	0.6
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	-0.2	0.5	-0.1	-0.2	-0.3	0.3	-0.2	-0.2	-0.3
Ever had bowel cancer screening	0.1	0.1	0.7	-0.1	-0.4	0.0	-0.1	-0.2	0.9	-0.2	-0.3	-0.3
Average weekly champagne plus white wine intake	0.1	0.2	0.9	0.0	0.9	-0.0	-0.2	0.1	0.0	-0.5	-0.2	-0.5
Leg fat percentage (left)	0.1	0.4	0.9	-0.9	-0.6	0.6	-0.7	0.8	0.1	0.4	-0.5	-0.4
Pack years of smoking	0.1	0.2	1.1	-0.2	-0.5	-0.6	0.3	-0.3	1.1	-0.0	-0.1	-0.1
Coronary Artery Disease (CAD)	0.0	0.0	0.1	-0.2	0.2	-0.3	0.3	-0.2	-0.0	0.0	0.1	0.0
Blood Platelet Count	0.0	0.6	2.1	-0.5	1.4	1.1	-0.2	0.5	-0.8	0.6	-0.3	-0.0
Hair Pigment	0.0	1.0	1.6	1.1	-0.9	-0.7	1.2	-1.2	0.2	1.3	1.1	0.5
Tanning	0.0	0.4	2.0	-0.4	-1.4	-0.6	-0.0	0.7	-0.4	-0.3	-0.7	0.4

Hub : Genes

BAG3

Models

Trait associations