TWAS hub - CTU2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0970	0.0260	3.4e-06	0.066	0.042	0.080	0.066	0.081	1.7e-08	6.2e-06	6.2e-10	2.0e-08	4.0e-10
2	GTEx	Adipose Visceral Omentum	0.2330	0.0870	9.2e-03	-0.003	NA	0.005	NA	0.002	5.4e-01	NA	1.7e-01	NA	2.6e-01
3	GTEx	Brain Hypothalamus	0.3450	0.1080	8.1e-03	0.012	NA	0.001	NA	0.017	1.6e-01	NA	3.0e-01	NA	1.3e-01
4	GTEx	Cells EBV-transformed lymphocytes	0.3430	0.0890	2.1e-03	0.107	NA	0.135	NA	0.152	2.3e-04	NA	3.7e-05	NA	1.2e-05
5	GTEx	Cells Transformed fibroblasts	0.1650	0.0480	6.7e-04	0.040	NA	0.044	NA	0.049	5.6e-04	NA	3.2e-04	NA	1.5e-04
6	GTEx	Colon Transverse	0.2090	0.0770	3.9e-03	-0.003	NA	-0.006	NA	-0.005	4.9e-01	NA	9.7e-01	NA	7.7e-01
7	GTEx	Esophagus Muscularis	0.1310	0.0460	2.7e-03	0.001	NA	0.003	NA	-0.002	2.9e-01	NA	2.2e-01	NA	4.6e-01
8	GTEx	Heart Left Ventricle	0.2123	0.0757	2.1e-03	0.037	NA	0.019	NA	0.045	4.4e-03	NA	3.4e-02	NA	2.0e-03
9	GTEx	Skin Sun Exposed Lower leg	0.1770	0.0480	1.7e-04	0.089	NA	0.066	NA	0.072	8.0e-08	NA	3.7e-06	NA	1.3e-06
10	METSIM	Adipose	0.0483	0.0198	4.7e-03	-0.001	0.004	-0.002	0.003	-0.002	5.4e-01	8.3e-02	8.0e-01	8.9e-02	7.1e-01
11	TCGA	Bladder Urothelial Carcinoma	0.0640	0.0320	3.6e-03	0.033	0.030	0.021	NA	0.022	7.7e-04	1.3e-03	6.2e-03	NA	5.6e-03
12	TCGA	Breast Invasive Carcinoma	0.0283	0.0113	1.2e-04	0.005	0.017	0.011	NA	0.009	3.0e-02	1.3e-04	1.6e-03	NA	4.1e-03
13	TCGA	Colon Adenocarcinoma	0.0830	0.0430	7.8e-03	0.064	0.024	0.037	NA	0.043	1.5e-04	1.4e-02	3.4e-03	NA	1.6e-03
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0357	0.0206	9.6e-03	0.002	0.010	0.006	NA	0.004	1.9e-01	2.6e-02	6.0e-02	NA	1.1e-01
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.1942	0.0459	0.0e+00	0.147	0.172	0.175	NA	0.180	3.3e-16	6.7e-19	3.1e-19	NA	8.5e-20
16	TCGA	Brain Lower Grade Glioma	0.0975	0.0308	1.7e-08	0.040	0.082	0.080	NA	0.066	2.0e-05	1.4e-09	2.3e-09	NA	6.1e-08
17	TCGA	Lung Adenocarcinoma	0.0518	0.0253	1.5e-03	0.047	0.023	0.016	NA	0.040	3.2e-06	9.3e-04	4.4e-03	NA	1.7e-05
18	TCGA	Lung Squamous Cell Carcinoma	0.0425	0.0213	3.1e-03	0.005	0.018	0.013	NA	0.012	8.3e-02	3.0e-03	1.1e-02	NA	1.3e-02
19	TCGA	Ovarian Serous Cystadenocarcinoma	0.0780	0.0310	7.7e-04	0.013	0.058	0.038	NA	0.035	4.0e-02	9.2e-05	1.3e-03	NA	1.9e-03
20	TCGA	Prostate Adenocarcinoma	0.0760	0.0335	2.7e-04	0.046	0.023	0.018	NA	0.038	1.3e-05	1.6e-03	4.6e-03	NA	6.5e-05
21	TCGA	Soft Tissue Sarcoma	0.0880	0.0390	2.1e-03	0.022	0.021	0.027	NA	0.027	1.7e-02	2.0e-02	9.7e-03	NA	9.4e-03
22	TCGA	Thyroid Carcinoma	0.0910	0.0370	4.6e-04	0.022	0.023	0.021	NA	0.026	2.7e-03	2.2e-03	3.3e-03	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Hair Pigment	7.4	212.1	635.0	-21.5	0.7	-2.3	-13.0	-12.2	-14.9	-12.0	-23.1	-16.2	-4.6	-25.2	-15.7	5.4	-13.3	-8.3	-19.0	-19.3	2.3	-12.6	-4.8	-24.4	-4.9
Depressed Affect (Nagel 2018)	5.2	10.8	27.7	-1.6	-2.0	-1.8	-3.6	-3.6	-2.2	-3.5	1.6	-3.6	-2.1	-4.2	-3.4	-2.6	-5.3	-3.3	-2.7	-4.7	-3.2	-2.8	-2.9	-5.1	-3.0
Neuroticism (Nagel 2018)	5.1	11.9	25.4	-1.1	-2.6	-1.1	-4.5	-4.4	-2.1	-3.8	2.1	-4.3	-1.3	-3.5	-3.1	-2.5	-5.0	-4.1	-2.6	-5.0	-2.6	-2.9	-3.6	-4.9	-3.9
Loneliness, isolation	5.1	7.0	15.1	-1.8	-1.6	-0.6	-3.4	-3.4	-1.8	-2.2	0.1	-3.7	-2.2	-3.4	-3.1	-1.4	-3.9	-3.3	-2.4	-2.9	-1.5	-1.4	-2.9	-3.7	-2.9
Fed-up feelings	4.5	8.2	22.0	0.0	-1.3	-1.4	-2.8	-3.1	-1.3	-3.0	1.3	-2.5	-2.0	-3.4	-2.5	-3.0	-3.9	-2.6	-1.8	-4.7	-3.9	-3.5	-2.5	-4.5	-2.6
Tanning	4.3	52.7	182.2	9.5	-1.5	-3.3	7.2	6.4	6.3	5.1	10.3	8.4	-2.0	11.6	5.8	-4.8	6.4	3.6	8.8	11.7	-2.2	8.1	1.6	13.5	1.9
Osteoarthritis (self-reported)	4.0	5.2	9.4	-0.6	-1.8	-1.5	-2.4	-2.8	-1.8	-2.4	1.1	-2.4	-2.0	-2.6	-2.1	-2.6	-2.7	-2.7	-1.4	-2.4	-3.1	-2.7	-2.2	-2.5	-2.8
Supplements: Fish oil (including cod liver oil)	3.7	4.8	11.0	-1.6	-1.1	0.8	-2.3	-2.7	-3.0	-0.8	-1.9	-2.4	-0.8	-1.9	-2.5	-2.2	-2.1	-2.9	-2.2	-1.7	-2.1	-3.3	-2.3	-2.3	-2.8
Worry (Nagel 2018)	3.6	7.5	15.9	-0.5	-3.5	0.3	-4.0	-3.7	-1.5	-3.0	2.0	-3.6	-1.0	-1.8	-2.0	-1.6	-3.9	-3.7	-1.8	-3.5	-1.0	-1.5	-3.5	-3.4	-3.5
Hypothyroidism/myxoedema (self-reported)	3.2	6.3	12.2	1.7	1.8	1.0	3.4	2.7	3.1	1.3	-1.1	2.8	1.5	2.9	3.0	2.4	2.2	3.3	2.7	2.0	2.1	2.3	3.5	2.3	3.4
Neuroticism	3.0	7.2	21.6	-0.1	-2.1	-1.3	-2.9	-2.9	-1.2	-3.2	3.2	-2.5	-1.4	-2.8	-2.0	-2.0	-4.4	-2.6	-1.0	-4.6	-2.2	-1.8	-2.4	-4.6	-2.5
Ever had prostate specific antigen (PSA) test	2.7	3.1	6.4	-2.5	-0.6	-1.5	-1.6	-1.1	-2.1	-0.4	-0.4	-1.5	0.5	-2.4	-2.5	-2.1	-1.6	-2.2	-2.4	-1.2	-1.7	-1.3	-1.6	-2.2	-2.4
Depression (Nagel 2018)	2.6	3.9	8.5	-2.2	-0.5	-0.1	-2.5	-2.5	-1.4	-1.3	1.0	-2.6	-0.2	-2.5	-2.3	-1.6	-2.9	-2.5	-1.6	-2.1	-1.4	-1.5	-2.0	-2.6	-2.3
Eye problems/disorders: Diabetes related eye disease	2.6	2.8	9.1	2.0	0.1	1.9	1.4	1.5	0.5	1.7	1.1	2.0	1.4	3.0	2.6	1.0	1.5	1.0	2.5	2.5	0.7	1.5	0.7	1.8	0.9
Tinnitus: Yes, but not now, but have in the past	2.6	2.7	6.6	0.3	-0.9	-0.5	-2.4	-1.6	-2.0	-1.5	1.5	-1.6	0.0	-0.9	-1.7	-1.1	-2.6	-1.8	-0.7	-1.7	-2.4	-2.1	-1.8	-2.1	-1.9
Birth weight of first child	2.6	4.7	8.7	2.0	0.6	1.4	2.8	2.9	2.2	0.7	1.1	2.6	1.2	2.4	2.8	2.0	1.3	2.8	2.8	1.0	2.4	2.6	2.9	1.2	2.8
Angina (self-reported)	2.6	3.4	8.5	-1.4	-0.0	-2.6	-1.9	-1.9	-1.0	-0.7	0.6	-2.1	-0.6	-2.3	-2.9	-1.7	-2.5	-1.9	-1.8	-1.8	-2.2	-1.8	-1.5	-2.1	-1.9
Mood swings	2.5	4.5	13.0	0.4	-0.8	-2.9	-1.4	-1.9	-0.4	-3.6	2.5	-1.3	-1.5	-2.5	-1.7	-1.7	-3.1	-1.1	-0.7	-3.5	-2.8	-1.5	-1.1	-3.6	-1.0
High blood pressure (mother)	2.4	3.4	9.6	-1.5	-3.0	0.1	-2.8	-2.7	-0.9	-1.9	-0.5	-3.1	-1.3	-1.8	-1.8	0.2	-1.4	-2.3	-2.0	-1.6	0.4	-0.8	-2.0	-1.7	-2.0
Hair/balding pattern: Pattern 2	2.4	3.0	8.1	-1.3	-2.2	-0.2	-2.0	-2.4	-1.7	-1.0	-0.4	-2.7	-2.9	-2.3	-1.8	-0.2	-2.0	-1.6	-1.7	-1.3	-0.6	-1.1	-2.0	-1.8	-1.2
Frequency of depressed mood in last 2 weeks	2.3	3.2	8.2	-0.1	-1.1	-1.0	-2.1	-2.5	-0.9	-1.6	1.9	-2.3	-0.4	-1.8	-1.4	-1.6	-2.5	-1.9	-0.5	-2.8	-2.0	-1.2	-1.6	-2.9	-1.9
Neuroticism score	2.3	4.8	17.7	1.1	-1.7	-0.5	-2.5	-2.5	-0.4	-3.1	3.0	-2.1	-1.2	-1.7	-0.9	-1.2	-3.5	-1.8	-0.1	-4.2	-1.6	-1.2	-1.8	-3.9	-1.8
Alzheimer’s Disease (in father)	2.2	2.4	7.3	0.1	-0.8	0.5	-1.8	-1.9	-2.0	-0.5	-0.5	-0.5	0.3	-0.7	-1.4	-2.6	-1.5	-2.3	-0.9	-1.9	-1.7	-2.3	-1.8	-1.0	-2.7
Hypothyroidism (self reported)	2.2	5.1	10.9	1.6	1.9	1.0	3.0	2.2	2.6	1.6	-1.2	2.5	0.9	2.3	2.8	2.2	2.2	3.2	2.6	1.2	2.1	1.8	3.3	2.1	3.2
Worrier / anxious feelings	2.2	4.2	14.2	0.7	-1.3	0.6	-2.9	-2.4	-0.5	-3.8	2.0	-2.7	-0.3	-0.6	-1.1	-1.1	-2.8	-2.4	-1.2	-3.4	-1.1	-1.1	-2.3	-2.8	-2.3
Mineral and other dietary supplements	2.2	3.0	6.1	1.6	1.3	-1.0	2.1	2.4	2.5	0.1	1.1	1.9	0.8	1.1	1.9	1.6	1.7	2.5	1.7	0.9	1.4	2.3	2.3	1.2	2.3
Angina	2.1	2.7	6.9	-1.3	-0.2	-2.5	-1.8	-1.8	-0.8	-0.4	0.5	-1.8	-0.5	-2.0	-2.6	-1.4	-2.3	-1.8	-1.6	-1.5	-2.0	-1.6	-1.5	-1.7	-1.8
Serious illness, injury or assault to yourself	2.1	2.5	4.8	1.2	0.9	0.6	1.6	1.7	1.9	0.6	-0.3	1.8	1.4	1.5	2.0	1.9	1.7	1.8	1.9	1.3	1.6	2.2	2.0	1.3	1.9
Time employed in main current job	2.1	2.4	5.5	-0.5	-1.1	-0.2	-1.9	-1.9	-1.3	-0.2	0.8	-1.5	-0.2	-1.5	-1.9	-1.7	-1.7	-2.1	-1.2	-1.7	-1.9	-2.1	-1.6	-1.7	-2.3
Pain experienced in last month	1.9	3.1	13.5	-0.4	1.3	2.8	0.1	0.2	-0.8	3.7	-3.2	0.9	2.2	1.3	0.6	1.6	2.4	0.5	-0.4	2.0	2.3	0.4	0.2	2.8	0.4
Blood Platelet Count	1.8	20.7	104.0	8.1	3.3	1.5	2.3	2.2	3.4	0.7	10.2	2.9	4.0	6.2	6.6	3.4	1.8	4.3	7.5	0.0	2.2	3.7	4.0	2.2	3.8
Hand grip strength (right)	1.8	4.8	12.6	1.7	2.0	1.0	2.5	2.5	2.2	1.1	-1.5	2.2	0.4	3.5	2.5	1.8	2.9	2.2	1.8	2.8	1.8	1.9	2.3	2.9	2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.3	4.8	-0.0	-0.8	-0.5	-1.8	-2.0	-1.4	-0.8	1.7	-1.6	-0.2	-1.0	-1.3	-2.0	-2.2	-2.0	-0.5	-1.6	-2.0	-1.1	-1.8	-1.9	-2.1
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.8	13.7	3.7	1.6	0.6	2.4	2.1	1.0	-0.9	1.5	2.7	1.2	3.3	3.0	-1.6	1.7	1.5	2.8	1.0	-0.6	1.0	1.2	2.0	0.8
Medication: Bendroflumethiazide	1.8	2.7	9.5	-0.4	-2.2	1.2	-2.3	-3.1	-0.4	-0.7	1.1	-2.6	-1.0	-1.4	-1.3	0.3	-2.3	-1.4	-1.3	-2.7	0.1	-0.7	-1.1	-2.3	-1.0
Neuroticism (2016)	1.7	2.4	8.6	0.9	-1.4	-0.1	-2.0	-1.5	-0.9	-1.4	0.9	-1.5	-0.0	-1.6	-0.8	-1.2	-2.3	-1.7	-0.5	-2.8	-1.6	-1.1	-1.7	-2.9	-1.6
Height	1.7	32.6	146.4	12.1	2.4	1.0	6.0	5.6	0.8	1.4	5.2	7.1	6.8	10.7	8.1	-4.6	4.8	3.8	7.7	3.0	-3.6	0.5	3.2	6.5	1.6
Medication: Levothyroxine sodium	1.7	2.8	5.2	0.4	1.4	1.2	2.1	1.5	2.3	1.1	-1.8	1.3	1.0	1.8	1.6	1.9	1.8	2.0	1.0	1.8	1.9	1.5	2.0	2.0	2.2
Medication for hormone replacement therapy	1.6	1.7	7.2	0.8	-0.5	-1.1	-0.8	-0.7	-2.7	-0.4	2.2	-1.3	0.5	-0.8	-0.6	-1.4	-2.0	-0.9	0.1	-2.3	-1.4	-0.0	-0.6	-2.1	-1.0
Illnesses of mother	1.6	2.0	6.6	0.8	2.6	-0.2	2.4	2.0	1.7	1.1	0.1	1.9	-0.0	1.0	1.4	-0.6	0.9	1.7	1.5	1.0	0.1	1.2	1.6	1.2	1.6
Loud music exposure frequency	1.6	1.7	5.0	-0.5	0.4	0.1	-1.9	-2.0	-1.3	-0.2	0.6	-1.8	-0.5	-1.5	-1.2	-0.7	-1.5	-1.6	-1.0	-2.2	-0.6	-1.1	-1.1	-2.0	-1.5
Tinnitus: Yes, now most or all of the time	1.6	1.8	5.9	-2.0	0.4	-0.7	-1.0	-0.2	-0.3	-1.8	-2.4	-0.4	0.1	-2.2	-1.8	-0.0	-0.8	-1.0	-2.3	-0.9	-0.6	-2.0	-0.3	-2.0	-0.6
Medication: Atorvastatin	1.6	2.0	4.2	-0.1	0.2	-0.5	-1.4	-1.4	0.2	-1.3	1.1	-1.3	-1.9	-1.7	-1.6	-1.5	-1.6	-1.2	-1.3	-1.6	-2.0	-2.0	-1.2	-2.0	-1.3
Blood Red Count	1.5	14.5	57.0	0.9	4.2	6.1	1.9	2.7	0.6	4.8	-2.1	2.0	7.5	5.2	4.0	3.1	5.1	1.6	2.1	5.5	3.5	1.5	1.9	5.4	1.5
Severe depression (siblings)	1.5	1.6	7.9	0.5	-0.3	-2.8	-0.0	0.2	-0.1	-2.6	0.9	0.3	-1.8	-1.4	-1.1	-1.6	-1.0	-0.2	0.4	-1.8	-1.6	-0.2	0.1	-1.9	-0.6
Trunk fat-free mass	1.5	8.5	33.3	5.8	1.3	-0.6	3.4	2.9	2.4	0.6	2.2	3.6	3.0	5.5	4.7	-2.6	2.1	2.1	4.2	1.1	-1.5	0.3	2.1	2.5	0.8
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	12.2	0.4	-1.1	-0.7	-0.3	-0.6	0.6	-2.5	1.6	-0.9	-3.5	-1.5	-0.1	-0.7	-2.2	-0.5	0.3	-2.1	-0.9	0.2	-0.1	-2.2	-0.1
Prospective memory result	1.5	1.8	9.6	1.8	1.4	-0.6	0.0	-0.9	-0.4	-1.1	3.1	0.4	-0.1	0.1	-0.2	-2.7	-0.7	-0.4	1.3	-2.2	-2.0	-1.6	-0.1	-0.1	-1.1
Trunk predicted mass	1.5	8.7	32.5	5.7	1.3	-0.6	3.5	2.9	2.4	0.6	2.1	3.6	3.1	5.5	4.7	-2.5	2.3	2.1	4.2	1.2	-1.4	0.4	2.2	2.7	0.8
Standing height	1.5	14.7	68.9	8.3	1.6	0.8	3.8	3.3	1.0	0.6	3.6	4.5	4.7	7.4	5.7	-3.5	2.8	2.2	5.4	1.6	-2.6	-0.1	1.8	4.0	0.7
Blood clot in the leg (DVT)	1.5	1.9	6.6	-0.7	1.2	0.0	1.6	1.9	1.2	0.8	-1.5	1.4	1.5	0.8	0.8	0.6	2.0	1.4	0.4	2.4	1.3	0.5	1.2	2.6	1.2
Chronic bronchitis/emphysema (mother)	1.5	1.7	4.6	1.1	1.4	-0.8	1.7	1.6	1.0	0.5	-0.3	1.8	-0.4	0.6	1.2	1.3	1.4	2.0	1.3	0.2	0.9	1.4	2.1	1.0	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	4.3	-0.0	-0.6	-0.5	-1.6	-2.1	-1.3	-1.6	0.3	-1.0	0.0	-1.0	-1.4	-1.8	-1.4	-1.9	-1.0	-1.2	-2.0	-2.0	-1.8	-1.3	-2.0
Health satisfaction	1.5	1.9	4.2	0.9	-1.2	-1.8	-0.7	-0.7	-1.9	-2.0	2.0	-0.4	-1.6	-1.2	-0.9	-1.6	-1.5	-0.9	0.2	-1.8	-2.0	-0.8	-0.3	-1.6	-1.3
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	8.2	-2.2	-0.6	1.2	-1.3	-0.9	-0.8	-0.5	-2.2	-1.2	-0.9	-0.6	-1.9	-0.6	-0.2	-1.5	-2.9	0.7	-0.2	-1.7	-1.7	0.6	-1.5
Whole body fat-free mass	1.5	8.5	29.3	5.4	1.5	-0.4	3.6	2.9	2.6	0.6	1.9	3.7	2.7	5.4	4.6	-2.3	2.5	2.2	4.1	1.5	-1.4	0.3	2.2	2.9	1.0
Guilty feelings	1.5	2.3	6.3	0.3	1.1	-0.4	-1.6	-1.6	-0.7	-2.0	2.5	-1.8	-0.2	-1.0	-0.4	-1.5	-2.1	-1.6	-0.1	-2.4	-1.1	-0.6	-1.5	-2.4	-1.7
Commuting to job workplace: Public transport	1.5	1.8	5.6	0.0	-1.7	1.6	-2.0	-2.4	-0.8	-0.7	1.0	-2.2	-0.7	-0.1	-0.3	1.5	-1.9	-1.1	-0.9	-1.5	0.8	-0.0	-1.2	-1.8	-0.6
Irritability	1.5	2.5	13.9	0.7	-0.2	-1.3	-1.4	-1.9	-0.2	-2.2	1.6	-1.4	-1.3	-1.1	-0.6	-0.5	-2.7	-0.5	-0.3	-3.7	-1.2	-1.4	-0.2	-3.1	-0.6
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	5.5	0.2	-0.3	-0.3	-1.5	-0.7	-1.2	0.1	1.9	-1.2	1.1	-0.9	-1.2	-2.3	-1.2	-1.4	-0.5	-1.8	-2.1	-1.9	-1.7	-1.2	-1.8
Reaction Time	1.4	2.7	10.5	2.1	0.4	0.5	1.4	1.3	2.0	1.5	2.9	2.1	0.4	1.9	2.0	0.8	0.6	1.7	3.2	0.6	0.5	1.7	1.7	1.0	1.5
Qualifications: None of the above	1.4	3.1	6.6	-1.4	-1.2	-1.6	-1.8	-2.5	-0.3	-0.9	-0.6	-2.1	-1.1	-2.1	-2.1	-2.5	-1.3	-2.4	-1.2	-1.6	-1.6	-1.4	-2.4	-1.4	-2.6
Medication for pain relief, constipation, heartburn	1.4	2.3	6.0	1.0	1.1	1.5	0.9	0.8	0.4	2.5	-1.6	1.4	1.0	2.0	1.3	2.2	2.2	1.1	0.2	2.2	2.1	1.3	0.7	1.9	1.3
Medication: Ibuprofen	1.4	1.7	8.2	0.8	-0.7	-0.8	-0.5	-0.7	0.4	-2.3	1.9	-0.8	-2.9	-1.2	-0.1	-0.8	-2.0	-0.7	0.4	-1.9	-1.2	-0.0	-0.2	-2.1	-0.4
Leg fat-free mass (right)	1.4	7.2	23.9	4.1	2.1	-0.2	3.4	2.8	2.6	0.7	1.0	3.5	2.3	4.9	4.0	-1.7	2.9	2.1	3.6	2.4	-1.0	0.1	2.1	3.5	1.0
Back pain experienced in last month	1.4	2.1	5.7	2.3	0.2	-0.0	1.4	1.5	2.4	-1.2	2.3	1.4	-1.4	1.0	1.8	0.9	0.0	1.6	2.1	-0.5	0.3	1.0	1.7	-0.5	1.7
Whole body water mass	1.4	8.2	29.1	5.4	1.3	-0.5	3.5	2.9	2.5	0.5	1.9	3.7	2.6	5.3	4.5	-2.4	2.4	2.1	4.1	1.4	-1.5	0.3	2.2	2.8	0.8
Leg predicted mass (right)	1.4	7.4	24.2	4.1	2.1	-0.2	3.5	2.8	2.7	0.7	1.0	3.6	2.3	4.9	4.0	-1.6	2.9	2.1	3.6	2.4	-1.0	0.2	2.2	3.5	1.1
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	5.5	-0.4	1.3	-0.3	1.7	2.0	1.2	0.8	-1.3	1.6	1.3	0.6	0.8	0.3	1.9	1.5	0.6	2.0	1.2	0.5	1.3	2.3	1.3
Supplements: Glucosamine	1.3	1.7	4.7	-2.2	0.4	-1.4	-0.5	-0.9	-1.4	0.4	-1.0	-0.5	-1.4	-1.6	-2.0	-2.0	-1.2	-1.4	-1.0	-0.9	-1.5	-1.3	-0.9	-1.2	-1.5
Medication: Atenolol	1.3	1.6	6.7	-2.6	-1.1	-1.0	-0.6	-0.5	-0.4	-1.1	-1.1	-1.1	-1.7	-2.4	-2.4	0.4	-0.8	-0.5	-1.8	-0.4	-0.4	-0.9	-0.1	-1.4	-0.2
Leg predicted mass (left)	1.3	7.0	21.4	4.5	1.7	-0.5	3.5	2.8	2.3	0.4	1.5	3.5	2.0	4.6	4.0	-1.9	2.6	2.1	3.8	1.9	-1.4	0.1	2.3	2.9	1.0
Nervous feelings	1.3	2.4	6.0	1.7	-1.7	1.0	-2.3	-2.2	-0.9	-1.6	2.4	-1.8	0.6	0.5	-0.2	-1.2	-1.7	-1.9	-0.0	-2.0	-0.5	-0.6	-2.1	-1.4	-2.2
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	6.1	-0.7	-1.3	-0.5	-1.2	-1.3	-0.2	-1.8	0.7	-1.6	-1.3	-1.4	-1.2	-0.3	-2.5	-0.9	-0.9	-1.9	-1.3	-0.9	-0.5	-2.2	-0.6
Wheeze or whistling in the chest in last year	1.3	2.4	11.9	2.1	-2.9	-1.4	-0.6	-1.1	-0.1	-2.2	3.5	-0.5	-0.9	-1.1	0.6	-0.2	-1.7	0.2	0.9	-2.8	-0.8	0.3	0.0	-2.1	0.3
Medication: Omeprazole	1.3	1.6	4.0	-0.3	-0.4	-0.6	-1.3	-0.6	-1.4	-0.4	1.1	-1.0	0.4	-1.3	-1.4	-2.0	-1.0	-1.3	-0.8	-2.0	-1.8	-1.9	-1.3	-1.5	-1.7
Basal metabolic rate	1.3	7.4	29.1	5.4	1.3	-0.5	3.2	2.5	2.3	0.4	2.3	3.4	2.3	4.9	4.3	-2.5	2.2	1.9	4.0	1.1	-1.6	0.1	1.9	2.5	0.7
Arm fat-free mass (left)	1.3	6.4	29.9	5.5	0.9	-0.3	2.8	2.2	2.1	0.4	2.2	3.0	2.1	4.6	4.0	-2.5	1.9	1.7	3.6	0.5	-1.3	0.1	1.6	2.2	0.5
Number of treatments/medications taken	1.2	2.2	6.1	-0.3	-1.1	-0.4	-1.7	-2.1	-0.7	-1.3	1.9	-1.9	-0.1	-1.5	-1.2	-1.3	-1.9	-1.4	-0.5	-2.5	-1.5	-1.5	-1.2	-2.1	-1.5
Sensitivity / hurt feelings	1.2	2.0	5.8	0.5	-1.4	-0.5	-1.7	-2.0	0.1	-2.3	0.9	-1.4	-0.5	-1.1	-1.0	-0.8	-1.5	-1.3	-0.7	-2.4	-1.5	-1.8	-1.2	-2.1	-1.4
Leg fat-free mass (left)	1.2	6.6	20.2	4.4	1.6	-0.6	3.4	2.8	2.2	0.3	1.5	3.4	1.9	4.5	3.9	-2.0	2.5	2.0	3.6	1.8	-1.5	0.0	2.2	2.8	0.9
Pulse rate	1.2	2.1	6.2	1.8	-0.0	1.5	0.8	0.6	2.2	0.7	2.5	1.1	1.7	1.7	2.1	1.6	0.7	1.3	1.5	0.2	1.5	1.8	1.2	0.5	1.3
Medication: Ventolin 100micrograms inhaler	1.2	1.5	7.6	-0.1	0.3	-0.1	1.0	0.6	1.6	-0.4	0.3	0.1	-1.0	-0.1	1.2	2.8	0.0	1.7	1.0	0.2	1.5	1.9	2.0	-0.4	2.3
Overall health rating	1.2	2.5	5.3	1.1	-1.0	-0.6	-1.6	-1.9	-0.7	-2.2	1.9	-1.8	-0.7	-1.3	-1.2	-1.5	-2.3	-1.7	-0.5	-2.3	-1.9	-1.5	-1.4	-2.3	-1.6
Medication: Gliclazide	1.2	1.4	6.1	0.7	2.5	-0.4	1.4	1.7	0.6	1.4	0.2	1.5	1.3	0.3	1.1	0.6	1.3	1.5	1.2	0.7	0.3	0.6	1.6	0.8	1.2
Alcohol drinker status: Previous	1.2	1.3	6.8	-2.6	0.7	-2.1	-0.1	-0.4	-0.7	-1.6	-0.2	-0.8	-0.4	-1.9	-1.6	-0.5	-1.0	-0.3	-1.5	-0.7	-0.6	-0.1	0.1	-1.6	-0.2
Arm predicted mass (left)	1.2	6.3	28.9	5.4	0.7	-0.3	2.8	2.1	2.0	0.4	2.5	2.9	2.3	4.7	4.0	-2.7	1.7	1.6	3.6	0.4	-1.5	0.1	1.6	2.1	0.4
Ulcerative Colitis	1.1	1.6	3.8	1.1	-1.1	0.6	-1.9	-1.5	-0.4	-1.6	1.6	-1.1	-0.1	-0.3	-0.3	-0.6	-1.8	-1.4	-0.4	-1.7	-1.1	-1.5	-1.6	-1.4	-1.3
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.9	-1.0	-1.2	1.3	-1.3	-1.0	-1.1	-1.2	-0.6	-0.7	-1.0	-0.3	-1.0	-1.3	-1.3	-1.7	-1.4	-0.7	-0.1	-1.2	-1.6	-0.7	-1.7
Father’s age at death	1.1	1.4	4.0	1.9	-0.1	-0.2	1.9	1.7	0.7	-0.4	0.3	2.0	1.1	1.5	1.7	-0.9	1.0	1.0	1.9	0.4	-0.2	0.5	1.4	1.1	0.5
Lung cancer (father)	1.1	1.3	3.9	0.4	0.9	-0.2	0.7	1.4	2.0	1.8	0.4	0.8	-1.0	0.9	0.7	1.4	1.5	0.9	1.0	1.1	1.4	1.6	0.7	1.5	0.9
Arm fat-free mass (right)	1.1	5.8	27.9	5.3	0.6	-0.1	2.6	2.1	2.0	0.1	2.5	3.0	2.0	4.5	3.9	-2.6	1.3	1.4	3.5	0.1	-1.5	-0.1	1.5	1.7	0.3
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.7	1.9	-0.4	-1.6	1.7	1.3	1.0	0.5	0.1	1.3	0.7	1.3	1.5	-0.5	0.7	1.0	1.6	0.7	-0.5	0.9	1.2	1.2	0.9
Arm predicted mass (right)	1.1	5.7	26.7	5.2	0.6	-0.3	2.6	2.1	2.0	0.1	2.2	3.0	1.9	4.5	3.8	-2.7	1.4	1.4	3.5	0.3	-1.6	-0.1	1.5	1.9	0.3
Number of self-reported non-cancer illnesses	1.1	1.9	6.4	-0.4	0.3	-2.5	-0.7	-1.3	-1.1	-0.1	1.4	-1.3	-1.1	-2.2	-1.4	-1.5	-2.0	-0.8	-0.7	-2.1	-1.7	-0.7	-0.6	-2.1	-0.9
Ulcerative Colitis (UC)	1.0	1.9	4.8	-0.0	-0.9	-0.3	-1.5	-1.5	-0.9	-1.7	1.3	-1.3	-0.1	-0.9	-1.0	-1.0	-2.0	-1.4	-0.8	-2.0	-1.9	-1.9	-1.1	-2.2	-1.2
Mean Putamen Volume	1.0	1.2	3.7	-0.1	1.9	-1.9	1.7	1.6	1.0	-0.1	1.2	1.4	0.2	1.0	0.4	-0.5	0.3	1.0	0.9	1.1	-0.9	0.8	1.1	0.8	0.9
Average weekly spirits intake	1.0	1.3	7.2	2.0	-2.3	0.4	-0.8	-0.9	0.8	-0.1	2.7	-0.6	0.0	1.0	1.1	0.0	-0.9	-0.5	1.2	-1.6	0.1	0.1	-0.4	-0.8	-0.6
Medication: Co-codamol	1.0	1.1	3.5	0.5	-0.2	-1.6	-0.7	-0.7	-1.5	-1.5	0.3	-0.6	-0.5	-1.3	-0.7	-1.3	-0.6	-0.7	-0.0	-1.9	-1.6	-1.4	-0.3	-1.2	-1.0
Impedance of leg (right)	1.0	4.8	20.8	1.9	-2.0	0.7	-2.3	-2.0	-2.8	-1.6	3.5	-1.5	-1.6	-2.1	-1.1	-1.2	-3.2	-1.2	-0.0	-4.6	-1.5	-1.1	-1.6	-3.6	-1.1
Age when periods started (menarche)	1.0	2.3	7.3	-1.9	-0.0	1.1	-1.6	-1.4	-1.1	-0.6	-2.5	-1.3	-1.8	-1.3	-1.9	-1.1	-0.8	-1.7	-2.1	-0.7	-1.1	-2.7	-1.5	-0.3	-1.8
Number of incorrect matches in round	1.0	1.7	3.4	-1.2	-0.7	-1.4	-1.1	-1.1	-1.5	-0.8	0.8	-1.1	-1.3	-0.9	-1.8	-1.8	-1.7	-1.6	-0.6	-0.9	-1.9	-0.9	-1.2	-1.1	-1.8
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	4.7	0.7	-0.9	0.8	-1.6	-2.2	-0.8	-0.9	1.0	-2.1	-1.7	-0.4	-0.3	-0.1	-1.5	-1.1	0.2	-1.5	-0.3	-0.3	-1.2	-1.2	-1.0
Asthma	1.0	1.9	7.1	2.0	0.9	-1.9	0.7	0.5	0.7	0.3	2.7	0.6	0.2	0.3	1.5	1.9	-0.3	1.8	2.2	-0.3	0.4	1.5	1.6	-0.1	2.1
Depression (self-reported)	1.0	1.2	4.5	0.1	0.0	-1.4	-0.9	-0.8	-0.5	-1.9	1.2	-1.0	-2.1	-1.1	-0.9	-1.0	-1.0	-1.1	-0.2	-0.7	-1.3	-0.2	-1.3	-1.3	-1.1
Medication: Lansoprazole	1.0	1.1	3.4	0.7	-0.8	-1.7	-0.6	-0.7	-1.2	-1.5	1.3	-0.8	-1.2	-1.0	-0.9	-0.2	-1.6	-0.1	0.3	-1.2	-1.6	-0.9	0.0	-1.8	-0.0
Neck or shoulder pain in last month	1.0	1.4	9.8	0.5	0.6	-3.1	0.5	0.3	-0.4	-1.4	1.6	0.1	-0.3	-1.2	-0.6	-1.2	-1.2	0.1	0.2	-1.3	-2.4	-0.7	0.6	-1.7	0.0
Comparative height size at age 10	1.0	5.7	32.5	5.7	0.1	0.5	1.8	1.7	1.2	0.7	2.9	2.4	2.6	4.8	3.6	-2.4	1.3	0.9	3.5	0.5	-1.6	0.4	0.3	1.9	0.0
Supplements: Vitamin C	1.0	1.2	3.0	-0.0	-1.6	-0.2	-1.0	-1.5	-1.5	-0.1	-0.2	-1.3	-1.5	-0.6	-1.2	-1.3	-1.0	-1.0	-0.9	-1.1	-1.3	-1.7	-1.1	-0.4	-1.1
Hypertension (Self-reported)	1.0	2.7	6.8	-1.1	-2.5	0.7	-2.3	-2.6	-1.2	-1.3	0.7	-2.3	-1.0	-1.8	-1.9	-0.2	-1.7	-1.9	-1.6	-1.8	-0.7	-1.4	-1.4	-2.0	-1.6
Miserableness	1.0	1.8	6.2	-0.9	-0.8	-0.2	-1.3	-1.4	1.2	-1.8	0.9	-1.5	-2.3	-1.4	-1.0	-0.2	-2.0	-1.2	-0.7	-1.6	-0.5	-0.3	-1.2	-2.5	-0.8
Ever taken oral contraceptive pill	1.0	1.1	5.5	1.1	-2.2	-0.3	-0.0	-0.4	-0.2	0.5	2.3	-0.6	-0.7	0.5	1.1	1.2	0.1	0.4	1.4	0.1	0.9	2.4	0.4	-0.0	0.5
Irritable Bowel Disease (IBD)	0.9	2.0	5.4	0.5	-0.8	-0.4	-1.8	-2.1	-1.4	-2.3	0.9	-1.9	-0.7	-0.7	-0.6	-0.7	-2.0	-1.4	-0.5	-2.0	-1.6	-1.5	-1.6	-1.8	-1.3
HbA1C	0.9	1.0	4.5	-1.6	-0.3	-1.3	-0.1	-0.1	-1.6	-2.1	0.6	-0.9	-1.6	-0.8	-0.8	-0.4	-1.2	-0.5	-0.9	0.1	-0.7	-0.4	-0.5	-1.3	-0.3
Lung FVC	0.9	4.7	23.2	-4.0	0.1	1.6	1.4	2.5	0.1	1.8	-4.8	2.0	1.4	1.2	-0.7	1.0	2.6	0.7	-1.5	4.0	1.8	0.3	0.7	3.2	0.7
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.1	0.3	-0.2	-0.9	-1.1	-1.2	-1.7	-0.7	2.0	-1.3	0.1	-0.9	-0.9	-1.5	-1.0	-1.1	0.0	-1.3	-1.2	-0.5	-1.3	-0.7	-1.2
Maternal smoking around birth	0.9	1.3	3.6	-0.3	-0.6	-0.8	-1.1	-1.5	-1.4	0.2	-0.6	-1.9	0.1	-0.6	-1.0	-1.4	-1.0	-1.5	-1.0	-0.6	-1.8	-1.2	-1.2	-1.0	-1.5
High blood pressure	0.9	2.5	6.3	-0.8	-2.4	0.8	-2.2	-2.5	-0.8	-1.3	0.7	-2.2	-1.1	-1.8	-1.8	-0.2	-1.5	-1.8	-1.5	-1.8	-0.7	-1.5	-1.4	-2.0	-1.5
Heart attack	0.9	1.1	6.9	-2.4	0.7	-2.6	0.6	0.8	-0.5	-1.0	0.1	0.0	0.0	-2.1	-1.5	0.1	-0.4	0.6	-1.0	0.4	-0.3	0.2	0.7	-0.7	0.8
Medication: Ramipril	0.9	1.1	5.3	0.6	0.9	0.6	1.4	1.5	2.3	1.5	0.2	1.3	1.1	0.5	0.7	0.0	0.8	1.2	1.2	0.2	0.3	0.1	1.5	0.2	1.0
Leg fat percentage (right)	0.9	3.3	13.5	2.3	-1.2	-0.6	-0.7	-1.0	-1.4	-1.0	3.7	-0.3	-1.9	-1.6	-0.2	-2.3	-2.3	-0.8	0.9	-3.4	-2.0	-1.6	-0.7	-3.1	-1.1
Medication: Blood pressure	0.9	1.5	3.3	-1.0	-1.4	-0.3	-1.8	-1.8	0.0	-1.3	-0.1	-1.8	-0.8	-1.1	-1.7	0.5	-1.7	-1.2	-1.5	-0.8	-1.0	-1.3	-0.9	-1.5	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	4.6	-2.2	-1.4	1.1	-1.4	-1.3	-0.0	-0.2	-0.6	-1.8	0.2	-0.4	-0.9	1.5	-0.6	-0.9	-1.5	0.7	1.0	0.1	-0.8	-0.1	-0.5
Alcohol intake frequency.	0.9	2.0	8.2	-2.9	1.2	-2.1	-0.8	-0.7	-0.2	-1.7	-2.0	-0.7	-1.9	-2.4	-2.2	0.3	-0.4	-0.3	-2.3	-0.2	-0.7	-1.2	-0.4	-0.6	-0.2
Chest pain or discomfort	0.9	1.4	11.4	1.0	-0.5	-3.4	-0.4	-0.6	0.7	-1.1	2.0	-0.4	-0.1	-1.2	-0.8	-0.6	-1.3	0.1	-0.1	-1.6	-1.7	-0.5	-0.0	-0.9	0.1
Knee pain experienced in last month	0.9	1.4	6.9	1.1	0.5	-2.6	0.9	0.5	1.2	-1.9	2.6	0.6	-0.6	0.8	0.4	-1.8	-0.6	-0.1	1.4	-0.3	-1.7	0.1	0.4	-0.2	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	6.8	0.2	2.6	0.1	1.1	0.5	-0.2	1.7	0.3	1.2	1.7	0.8	0.5	0.1	0.8	0.9	0.9	1.1	-0.3	-0.3	0.8	0.9	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	4.5	0.4	0.6	1.1	0.0	0.6	0.1	1.4	0.2	-0.2	1.7	0.5	0.9	2.1	0.3	0.5	0.6	1.5	1.7	1.4	0.1	0.3	0.9
Average weekly beer plus cider intake	0.9	1.2	4.8	-0.2	-0.8	0.3	-1.7	-2.2	-0.3	1.2	1.9	-1.7	1.3	0.5	0.2	-0.5	-0.2	-1.3	0.6	0.1	0.3	0.2	-1.7	0.9	-1.5
Primary Biliary Cirrhosis	0.8	1.2	4.0	0.4	-1.3	0.2	-0.8	-0.7	-0.4	-2.0	0.1	-0.7	-2.0	-0.3	-0.9	-1.6	-0.6	-1.0	-1.0	-1.1	-1.4	-1.7	-1.1	-0.2	-1.2
Heel T-Score	0.8	6.7	31.1	5.6	3.2	0.8	2.0	0.8	1.5	1.3	2.4	2.1	3.1	4.3	4.1	0.3	2.5	2.2	4.1	-0.3	-0.9	0.7	2.6	2.0	1.6
Hand grip strength (left)	0.8	2.2	7.8	2.7	1.3	0.5	1.4	1.1	0.9	0.4	-2.0	1.5	0.0	2.8	1.8	1.1	2.2	1.4	0.9	1.4	0.6	0.5	1.3	1.9	1.2
Vitamin and mineral supplements	0.8	1.0	4.5	-0.9	2.1	0.1	0.5	0.9	1.2	0.4	-0.0	0.1	0.9	1.0	0.9	0.9	0.9	0.2	0.3	1.7	1.5	2.1	0.6	0.7	0.3
Relative age voice broke	0.8	1.2	2.6	-0.9	1.3	1.2	1.3	1.4	-0.0	1.1	-1.6	1.6	0.6	-0.2	0.6	1.4	0.9	1.4	0.2	0.9	1.6	1.0	1.0	0.4	1.6
Sitting height	0.8	5.7	19.9	4.5	1.4	-0.4	2.8	3.0	-1.0	-1.8	1.2	3.2	2.9	3.5	2.6	-3.7	1.9	1.2	3.1	1.1	-2.8	-1.0	1.1	2.0	0.0
Impedance of leg (left)	0.8	3.8	16.2	1.7	-1.3	1.3	-2.5	-2.3	-2.4	-1.0	3.0	-1.6	-1.1	-1.7	-1.1	-0.8	-2.8	-1.4	-0.1	-4.0	-1.0	-1.0	-1.9	-2.9	-1.1
Forced vital capacity (FVC)	0.8	2.9	14.7	1.3	-0.3	1.3	1.6	2.1	-0.2	0.3	-1.5	2.2	2.2	3.8	1.9	-0.4	2.1	1.0	0.8	2.3	0.1	-0.1	0.7	3.2	0.5
Weight	0.8	4.0	20.2	4.5	0.7	-0.5	2.1	1.3	1.1	0.1	3.0	2.2	1.0	3.0	2.9	-2.7	1.0	1.0	3.1	0.3	-2.0	-0.6	0.9	1.3	-0.0
Falls in the last year	0.8	1.1	4.2	1.5	0.2	-1.4	-0.4	-0.8	-0.4	0.3	1.7	-0.4	0.9	-0.2	-0.1	-1.9	-0.6	-0.8	0.7	-1.3	-2.1	-1.2	-0.7	-0.6	-1.2
Hair/balding pattern: Pattern 3	0.8	1.3	4.6	0.2	1.8	1.0	0.4	0.7	1.7	1.0	-0.7	0.1	-0.1	0.9	1.0	2.1	1.3	0.9	0.4	1.2	1.9	1.1	0.6	1.2	1.1
Pulse wave reflection index	0.8	1.0	8.5	-1.1	-0.4	0.4	-0.8	-0.1	-0.9	-1.3	-2.9	-0.9	-1.2	-1.1	-0.9	-0.0	-0.2	-0.6	-1.2	-0.2	0.1	-0.7	-1.0	-0.1	-0.4
Medication: Paracetamol	0.8	1.3	6.7	0.5	-1.1	-0.8	-0.9	-0.6	-0.0	-2.4	2.6	-0.4	-0.6	-0.5	-0.1	-1.4	-1.4	-0.5	1.2	-1.6	-1.2	-0.6	-0.9	-0.5	-0.8
Number of children fathered	0.8	0.9	3.4	-0.6	1.8	0.1	1.0	1.1	1.0	0.0	-1.4	1.1	1.8	0.7	0.1	-0.1	1.3	0.8	-0.1	1.3	-0.1	-0.4	1.1	1.1	0.6
Emphysema/chronic bronchitis	0.8	0.9	3.3	0.2	0.6	-1.6	1.4	1.0	0.4	0.4	-1.8	1.1	0.1	0.1	0.2	0.5	0.7	1.1	0.4	1.5	0.1	1.1	1.3	0.7	1.1
Mean time to correctly identify matches	0.8	1.5	3.1	0.8	0.1	0.9	0.9	1.2	1.5	1.6	1.2	1.6	1.1	1.5	1.1	1.2	0.9	1.2	1.8	1.4	0.8	1.4	1.0	1.3	1.1
Pulse rate, automated reading	0.8	2.7	13.2	3.4	-0.9	2.9	-0.7	-0.9	1.9	-0.1	3.6	0.0	2.4	1.5	2.2	0.3	-0.2	-0.1	1.6	-1.8	0.9	0.5	-0.4	-0.7	-0.3
Leg pain on walking	0.8	1.0	4.3	-0.2	-0.7	-1.1	-0.3	-0.8	-0.3	-1.1	1.4	-0.4	-0.0	-0.7	-0.8	-2.1	-1.0	-1.1	-0.3	-0.5	-2.0	-1.2	-0.9	-0.6	-1.4
Average weekly red wine intake	0.8	1.2	4.3	0.7	0.3	0.5	1.2	1.1	1.4	-1.3	-0.3	0.8	-0.5	1.0	1.1	1.7	0.6	1.0	0.2	1.5	1.5	2.1	1.2	0.6	1.4
Asthma (self-reported)	0.8	1.6	6.4	1.9	0.7	-1.8	0.6	0.4	0.5	-0.2	2.5	0.5	-0.2	0.1	1.3	1.7	-0.5	1.7	2.0	-0.5	0.2	1.2	1.6	-0.3	2.0
Medication: Paracetamol	0.8	1.2	5.8	0.4	-0.6	-1.4	-0.8	-0.7	-0.3	-2.4	2.4	-0.6	-0.3	-0.5	-0.2	-1.5	-0.9	-0.6	0.8	-1.4	-1.4	-0.6	-0.9	-0.4	-0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.1	6.7	-2.2	0.5	-2.6	0.7	0.8	-0.5	-1.1	0.2	0.1	-0.1	-2.0	-1.3	0.2	-0.4	0.6	-0.8	0.4	-0.3	0.3	0.8	-0.6	0.8
Alzheimer’s Disease (including proxy)	0.7	1.1	3.2	-0.0	-0.2	0.9	-1.5	-1.6	-0.9	-0.4	-0.5	-0.3	0.4	0.3	-1.0	-1.5	-0.6	-1.4	-0.8	-1.0	-1.2	-1.8	-1.3	-0.1	-1.8
Allergy or Eczema	0.7	1.8	4.6	-1.0	-1.3	0.1	-2.0	-2.1	-1.7	-1.9	-0.0	-1.9	-1.2	-1.5	-1.3	0.6	-1.3	-1.4	-1.3	-0.8	0.3	0.0	-1.6	-1.4	-1.1
Cardiovascular Disease	0.7	2.4	8.0	0.6	-2.8	0.2	-1.9	-1.9	-0.6	-1.3	2.3	-1.8	-1.7	-1.2	-0.9	-0.3	-2.3	-1.2	-0.2	-2.6	-1.0	-0.6	-1.0	-2.3	-1.1
Respiratory disease	0.7	1.5	6.0	2.0	-0.3	-0.9	0.1	-0.7	0.2	0.0	1.8	-0.2	0.3	-0.1	1.3	2.5	-0.9	1.5	1.3	-1.2	0.8	1.5	1.5	-1.0	2.0
Relative age of first facial hair	0.7	1.4	4.4	-1.3	0.9	0.2	1.3	1.7	-0.5	2.1	-1.7	1.5	1.0	0.2	0.1	1.4	0.7	1.4	0.5	1.1	1.0	0.6	1.4	0.5	1.5
Diabetes (father)	0.7	0.9	4.8	-0.2	0.8	-0.8	0.5	1.0	0.4	-2.2	0.4	0.7	-1.3	-0.8	-0.6	-1.4	-0.7	-0.0	-0.3	-0.5	-1.4	-0.9	-0.1	-1.8	-0.1
Pack years adult smoking proportion	0.7	1.1	5.5	0.4	0.6	-2.3	0.4	-0.0	-0.3	0.0	1.0	0.4	0.1	-1.2	-0.6	-2.2	-0.7	-0.1	0.6	-1.5	-2.1	-1.1	0.4	-1.1	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.2	0.9	-0.5	-1.0	-0.8	-1.1	1.8	-1.2	1.8	-0.4	-1.7	-1.4	-0.2	-0.2	-1.3	-0.4	0.3	-1.4	-0.6	-0.1	-0.6	-1.8	-0.3
Noisy workplace	0.7	0.8	5.6	-0.0	1.5	2.4	0.4	0.4	0.3	1.1	-0.8	0.8	-0.2	-0.1	0.4	0.8	1.2	0.5	0.7	0.8	1.3	0.5	0.4	1.0	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	10.4	0.8	0.0	0.7	1.6	2.0	-0.6	0.2	-1.8	2.2	1.6	3.2	1.2	-1.1	1.6	0.7	0.5	2.2	-0.8	-0.3	0.7	2.8	0.2
Hair/balding pattern: Pattern 4	0.7	1.8	11.0	-0.8	-0.7	-3.3	0.4	0.6	-1.2	-0.7	0.4	0.3	-0.1	-1.0	-1.6	-2.7	-0.9	-0.8	-0.7	-0.7	-2.5	-0.9	0.0	-1.2	-1.2
Peak expiratory flow (PEF)	0.7	1.6	4.3	0.0	0.3	0.2	1.7	2.1	1.1	0.5	-1.3	1.8	-0.2	1.9	0.9	0.6	1.3	1.4	0.9	1.8	0.7	1.2	1.6	1.9	1.2
Number of full brothers	0.7	0.8	7.1	0.4	2.7	-0.1	1.0	1.1	-0.1	1.1	-0.1	1.4	1.0	0.5	0.5	-0.4	1.4	0.9	0.4	0.6	0.2	0.1	0.8	0.7	0.4
Eye problems/disorders: None of the above	0.7	0.8	4.0	-0.8	0.8	-1.5	0.4	0.1	0.6	-2.0	-1.3	0.2	-1.6	-0.9	-0.7	-0.3	-0.4	0.7	-0.3	-0.8	-0.4	-0.6	0.5	-0.5	0.7
Long-standing illness, disability or infirmity	0.7	1.1	5.3	2.3	-0.3	-0.8	-0.4	-1.0	0.8	-1.3	2.2	0.0	0.8	0.3	0.6	-0.8	-1.1	-0.2	0.8	-1.4	-1.4	-0.8	0.0	-0.5	-0.4
Pain type(s) experienced in last month: Hip pain	0.7	0.9	4.2	0.8	1.1	-2.0	0.8	0.7	-0.9	-0.2	1.5	0.9	0.8	-0.2	-0.1	-1.9	0.1	-0.1	0.6	0.0	-2.0	-0.6	-0.1	-0.2	-0.3
Medication: Lisinopril	0.7	0.9	6.3	0.4	-1.6	0.6	-0.3	-0.4	0.6	-0.9	0.1	-0.6	0.4	1.4	1.1	2.5	0.3	0.5	0.1	0.9	1.6	1.0	0.4	0.5	0.8
Alcohol drinker status: Never	0.7	0.9	3.8	-1.1	-0.6	-0.4	-0.6	-0.5	0.6	-2.0	-1.2	-0.1	-1.8	-1.5	-1.2	0.1	-0.4	-0.2	-1.6	-0.7	-0.4	-1.1	-0.3	-0.5	-0.1
Leg fat percentage (left)	0.7	2.6	11.7	2.0	-0.7	-0.4	-0.8	-1.1	-0.9	-0.6	3.4	-0.3	-1.7	-1.3	-0.2	-2.1	-2.1	-0.8	0.9	-3.1	-1.7	-1.5	-0.8	-2.6	-1.1
Age started oral contraceptive pill	0.7	0.9	3.8	-0.7	0.7	1.2	0.5	0.4	-0.1	1.4	-1.6	0.8	1.9	0.4	-0.3	-0.8	1.2	-0.1	-0.8	1.0	0.2	-0.9	-0.2	1.5	-0.2
Vascular/heart problems diagnosed by doctor	0.7	2.0	4.7	1.0	1.6	-0.2	1.7	2.1	0.8	1.1	-1.1	1.8	0.8	2.0	1.8	0.3	1.6	1.4	1.4	1.7	0.8	1.2	1.0	2.2	1.2
Pack years of smoking	0.7	1.0	4.7	0.4	0.6	-2.1	0.1	-0.2	-0.4	0.3	1.1	0.2	0.5	-1.1	-0.7	-2.2	-0.7	-0.4	0.4	-1.2	-2.1	-1.4	-0.0	-0.8	-1.0
Breast Cancer	0.6	1.5	5.8	-1.5	-0.5	1.2	-0.1	0.1	0.6	2.2	-1.9	-0.1	1.0	0.4	0.2	1.0	0.9	-0.4	-0.7	2.4	2.0	1.9	-0.9	1.5	-0.2
Age at First Birth	0.6	0.9	6.2	0.4	1.0	0.7	0.2	0.3	1.2	2.0	-0.5	0.5	2.5	0.5	0.8	1.3	0.9	0.6	0.1	0.6	1.1	0.3	0.4	1.0	0.7
Lupus	0.6	0.9	2.7	-0.3	-1.6	-1.2	-0.7	-1.1	-1.0	-0.6	1.4	-0.6	-1.2	-1.1	-0.3	-1.1	-1.0	-0.9	-0.0	-0.8	-0.8	-0.3	-1.1	-0.5	-0.9
Systolic Blood Pressure	0.6	3.3	8.4	-1.0	-2.7	-0.8	-2.0	-1.6	-0.7	-2.9	-0.4	-1.8	-2.9	-2.3	-1.9	-0.4	-1.7	-1.6	-1.9	-1.9	-0.9	-1.3	-1.6	-2.4	-1.4
Taking other prescription medications	0.6	0.9	3.5	0.1	0.3	-0.9	-0.7	-1.1	0.6	-0.5	1.9	-1.0	0.5	-0.9	-0.8	-1.6	-1.0	-0.7	-0.1	-1.3	-1.4	-0.9	-0.7	-0.4	-1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.0	-1.2	0.5	-0.7	-0.5	-0.8	-0.8	-0.8	0.1	-0.9	-0.5	-1.3	-1.0	-0.6	-0.9	-0.6	-0.8	-0.8	-0.9	-0.5	-0.3	-1.4	-0.6
Qualifications: CSEs or equivalent	0.6	0.8	4.7	-0.9	0.2	-1.6	-0.5	-0.4	-0.5	-0.5	-0.3	-0.7	-2.2	-1.2	-1.1	-0.4	-0.6	-0.6	-1.0	-0.1	-0.9	-0.6	-0.6	-1.2	-0.5
Multivitamins +/- minerals	0.6	0.8	5.7	2.4	-0.7	0.4	0.7	0.3	-0.1	0.2	0.8	1.4	0.7	0.1	0.6	-0.3	0.1	1.1	0.9	-1.4	-0.7	-1.1	0.8	0.0	0.9
Trunk fat mass	0.6	2.4	14.0	3.7	0.5	-0.2	1.0	0.4	0.2	0.0	3.3	1.4	-0.0	1.6	1.8	-2.6	0.2	0.2	2.5	-0.6	-2.1	-1.0	0.1	0.3	-0.6
Alcohol usually taken with meals	0.6	1.0	2.6	0.3	1.2	0.8	0.9	1.5	1.5	-0.4	-1.1	1.4	-0.8	1.4	0.8	1.1	1.0	0.8	0.0	1.6	0.9	0.9	0.5	1.0	0.9
Had menopause	0.6	0.7	6.2	0.5	0.3	1.2	0.6	0.7	-0.5	0.7	1.4	0.6	2.5	0.8	0.5	-0.2	0.6	0.6	0.7	0.4	-0.1	-0.3	0.4	1.1	0.4
Had other major operations	0.6	0.7	2.7	-0.8	-0.6	1.3	-1.3	-1.3	-0.3	-0.6	0.8	-1.6	0.2	0.2	-0.5	0.0	-0.9	-1.1	-0.9	-0.1	0.0	-0.3	-1.3	-0.4	-1.0
Mouth/teeth dental problems	0.6	0.9	4.8	-0.3	0.3	2.2	-1.3	-0.6	-1.2	1.4	-0.6	-0.6	0.7	-0.2	-0.5	-0.4	-0.0	-1.1	-1.0	-0.4	0.3	-0.9	-1.5	-0.5	-1.1
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	12.6	1.5	-0.8	0.6	1.1	1.6	-0.6	0.0	-0.9	1.8	1.8	3.5	1.1	-1.8	1.3	0.1	0.7	1.8	-1.5	-0.8	0.1	2.4	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.0	1.0	-0.6	-0.8	0.8	0.3	0.5	-0.3	0.6	1.0	0.4	0.6	1.1	1.0	1.1	1.1	1.4	-0.3	0.4	0.8	1.4	-0.1	1.0
Exposure to tobacco smoke at home	0.6	0.6	5.6	1.2	0.7	-0.4	-0.2	-0.1	-0.5	-0.5	2.4	0.7	0.1	0.4	0.6	0.4	0.2	0.6	1.6	-0.2	0.3	0.8	0.4	0.6	0.3
Tense / ‘highly strung’	0.6	1.0	3.1	0.5	-1.8	0.5	-1.6	-1.7	0.6	-1.1	0.7	-1.3	0.2	0.1	-0.1	-0.1	-0.8	-1.5	-0.2	-0.7	0.4	0.2	-1.5	-0.4	-1.5
High blood pressure (siblings)	0.6	0.8	3.4	-0.2	0.3	0.5	-0.1	-0.4	1.7	0.7	-0.4	-0.3	1.3	0.7	0.4	1.9	0.9	0.6	-0.4	1.1	1.5	1.1	0.4	1.0	0.7
Forced vital capacity (FVC), Best measure	0.6	2.2	9.5	0.8	0.2	1.2	1.6	1.9	-0.9	0.1	-2.0	2.1	1.6	3.1	1.5	-0.7	1.7	0.9	0.5	2.1	-0.4	-0.3	0.8	2.7	0.4
Number of full sisters	0.6	0.7	2.1	-0.3	1.4	-1.1	1.4	1.1	0.7	-0.4	-1.0	0.8	-1.2	-0.6	-0.4	0.0	0.4	1.0	-0.0	0.3	0.4	0.5	1.4	0.1	1.0
Suffer from ‘nerves’	0.6	1.0	2.9	1.4	-0.3	0.8	-1.4	-1.5	0.0	-1.1	1.7	-1.0	0.0	0.4	0.1	-0.5	-1.2	-1.1	0.6	-1.4	0.2	0.0	-1.5	-0.6	-1.2
Handedness (chirality/laterality): Left-handed	0.6	0.7	3.2	-0.9	1.8	0.2	0.0	1.0	-0.5	-0.0	-1.6	0.0	0.5	-0.3	-0.1	0.7	1.1	0.3	-1.3	1.2	1.0	-0.3	-0.1	1.0	0.3
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.3	0.2	0.2	-1.2	1.5	0.9	0.2	0.8	1.1	1.3	1.1	0.9	0.7	-0.0	0.6	1.2	1.2	0.9	0.2	1.2	1.5	1.4	0.8
Osteoporosis (self-reported)	0.6	0.7	4.4	-0.3	1.6	1.0	0.5	0.6	0.4	0.3	-1.2	0.7	0.9	0.4	-0.2	-0.6	1.1	0.1	-0.7	1.4	0.2	-0.3	-0.3	2.1	-0.1
Hearing aid user	0.6	0.7	4.1	-0.5	-1.4	-0.5	-0.4	-0.6	-0.9	0.8	0.8	-0.3	2.0	-0.9	-0.7	-0.0	-0.8	-0.3	-0.2	-1.0	-0.0	-0.2	0.3	-1.4	-0.1
Illnesses of father: High blood pressure	0.6	0.8	4.8	0.2	-1.3	0.4	-1.2	-1.5	1.2	-0.9	-0.2	-0.8	-2.2	-0.7	-0.0	0.4	-0.9	-0.3	-0.2	-0.8	0.1	-0.4	-1.0	-0.6	-0.1
Heart disease (siblings)	0.6	0.7	4.2	-0.8	1.1	-2.0	0.9	1.2	1.3	-0.3	-0.2	-0.0	-0.4	-0.6	-0.2	0.3	0.7	0.7	-0.3	0.8	0.2	1.1	0.6	0.1	0.8
Ovarian Cancer	0.5	0.7	4.6	-0.8	0.1	0.7	-0.3	-1.0	-0.4	2.1	-0.6	-1.1	1.9	0.2	-0.1	0.7	0.6	-0.2	-0.7	0.6	0.7	0.2	-0.6	0.3	-0.0
Fasting Glucose	0.5	0.6	2.1	0.5	0.5	-1.5	-0.2	-0.4	0.0	-0.3	0.0	0.0	-1.2	-1.4	-0.7	-1.2	-0.9	-0.1	0.2	-1.2	-1.1	-0.5	-0.4	-1.0	-0.2
Rheumatoid Arthritis	0.5	0.6	2.6	0.6	-0.4	-0.6	-0.3	-0.2	-0.8	1.2	1.6	-0.1	1.4	-0.4	-0.2	-1.6	-0.4	-0.5	0.6	-0.7	-0.9	-0.3	-0.7	-0.2	-0.8
Waist Hip Ratio (WHR)	0.5	2.4	10.6	3.3	0.3	1.8	0.8	0.3	3.0	-0.2	2.2	0.9	0.8	2.7	2.5	0.5	0.8	0.7	2.3	0.9	0.1	0.8	0.3	0.8	0.7
Lung FEV1/FVC ratio	0.5	2.5	12.8	2.0	-1.9	-2.0	0.0	-0.0	-0.1	0.6	2.4	0.5	-0.4	1.1	-0.2	-3.6	-1.3	-1.2	1.1	-0.7	-3.5	-0.9	-0.8	-0.7	-1.8
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.4	1.6	-1.3	1.0	-0.7	-0.8	0.1	-0.6	1.0	-0.7	0.5	0.7	0.6	-0.2	-1.1	-0.7	0.3	-0.5	-0.5	0.0	-0.8	-0.7	-0.6
Ever had hysterectomy (womb removed)	0.5	0.6	2.1	0.7	-1.5	0.8	-0.3	-1.0	-1.2	-0.5	1.4	-0.4	0.8	-0.2	0.2	-0.8	-0.3	-0.4	0.1	-1.0	-0.3	0.0	-0.6	-1.0	-0.5
Stomach or abdominal pain in last month	0.5	0.7	5.8	1.1	-1.0	-0.6	0.0	-0.3	-0.4	0.3	2.4	-0.3	1.3	0.9	0.9	-0.0	-0.7	-0.0	1.3	-0.3	-0.2	0.7	-0.0	-0.5	-0.0
Waist circumference	0.5	1.9	9.8	3.1	0.4	-0.6	1.2	0.4	1.7	-0.3	3.0	1.2	-0.2	1.4	1.8	-1.9	0.0	0.3	2.3	-0.2	-1.6	-0.1	0.3	-0.1	-0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	5.3	0.5	-1.0	-0.1	-0.0	-0.5	0.4	-1.8	1.5	-0.3	-2.3	-0.4	0.3	0.1	-0.0	0.1	0.2	-0.8	-0.0	0.5	0.1	-0.8	0.0
Pain all over the body in last month	0.5	0.6	4.3	-0.8	-0.6	-0.6	0.3	0.2	0.9	-2.1	-0.0	-0.0	-1.6	-1.2	-0.4	0.5	-0.0	0.4	-0.0	0.2	0.3	0.9	0.4	-0.3	0.4
Fluid intelligence score	0.5	1.1	4.8	-1.1	1.3	0.1	1.3	2.2	0.2	0.7	-1.8	1.0	0.4	-0.5	0.2	0.9	0.4	1.3	-0.4	0.9	1.0	1.0	1.2	0.1	1.6
Happiness	0.5	0.7	4.9	1.6	1.1	-0.2	0.1	0.9	-0.6	0.3	2.2	0.3	0.3	0.4	1.0	0.7	-0.5	0.6	1.0	-0.3	-0.1	0.8	0.4	-0.5	0.7
Length of working week for main job	0.5	0.6	3.9	0.5	0.0	2.0	0.2	0.1	0.6	0.8	1.1	0.3	1.1	1.5	0.6	-0.6	-0.2	-0.2	0.8	0.6	-0.6	-0.6	-0.2	0.8	-0.3
Breastfed as a baby	0.5	0.6	5.6	0.7	0.1	2.4	-0.1	-0.2	-0.2	0.4	0.1	0.4	-0.2	1.5	0.8	-0.3	0.9	-0.4	0.4	0.7	0.6	-0.6	-0.6	1.3	-0.6
Headache pain in last month	0.5	0.8	6.7	1.0	0.0	-2.6	0.4	0.4	1.3	-0.5	1.6	0.5	-0.0	-0.8	-0.1	-1.0	-0.7	0.5	0.6	-1.0	-1.0	0.0	0.1	-0.8	0.4
Exposure to tobacco smoke outside home	0.5	0.7	6.3	0.5	2.5	-1.2	0.7	0.1	1.1	0.4	0.2	0.6	-0.6	-0.6	-0.2	-1.0	-0.0	0.4	1.0	-0.9	-0.3	0.1	0.7	-0.4	0.1
Worry too long after embarrassment	0.5	0.8	3.4	0.3	0.2	-0.0	-1.5	-1.2	0.4	-0.3	1.1	-1.3	0.0	-0.5	-0.4	-0.0	-1.3	-0.9	-0.4	-1.8	-0.1	-0.2	-0.8	-1.6	-0.9
Shortness of breath walking on level ground	0.5	0.5	4.8	0.9	-0.9	-0.7	0.8	0.2	0.6	-2.2	0.7	0.9	-0.2	-0.6	0.3	-0.7	-0.0	0.5	0.4	-0.4	-0.4	0.1	0.8	-0.4	0.3
Medication: Allopurinol	0.5	0.7	3.8	0.1	-0.5	0.2	-1.4	-2.0	0.5	-0.2	-0.2	-1.0	-0.5	-1.1	-0.6	0.4	-0.8	-0.7	-0.7	-1.1	0.3	-0.7	-0.6	-0.9	-0.7
Medication: Seretide 50 evohaler	0.5	0.6	2.7	0.7	-0.8	-0.4	0.9	1.1	1.6	0.5	0.3	0.7	0.4	-0.3	0.7	0.5	0.3	1.3	0.3	0.4	-0.4	0.0	1.1	0.2	1.3
Heart disease (mother)	0.5	0.6	2.7	-0.6	-1.6	-1.6	-0.2	-0.3	-0.4	-0.2	0.9	-0.8	1.6	-0.7	-0.6	-0.0	0.0	-0.5	-0.5	0.7	-0.3	0.6	-0.4	-0.1	-0.5
Leg fat mass (right)	0.5	2.1	11.4	3.4	-0.0	-0.5	0.7	0.2	-0.1	-0.4	3.2	1.1	-0.6	0.5	1.3	-2.2	-0.7	0.2	2.1	-1.8	-1.9	-1.1	0.3	-1.2	-0.4
Had major operations	0.5	0.6	1.9	-1.3	1.1	0.2	0.2	0.4	0.3	0.6	-1.1	-0.5	0.5	-0.1	-0.3	0.9	0.7	0.1	-0.6	1.2	1.4	1.1	0.4	0.8	0.3
Commuting to job workplace: Car/motor vehicle	0.5	0.6	3.2	0.2	0.3	-0.4	0.4	1.1	0.7	0.5	-1.4	0.7	0.5	0.5	0.2	0.3	1.4	0.2	0.3	1.8	0.1	0.1	-0.1	1.5	0.1
Eye problems/disorders: Cataract	0.5	0.6	2.3	-0.2	-1.5	1.4	-1.1	-0.7	-0.6	1.0	0.8	-1.0	-0.5	0.1	-0.4	0.5	-0.8	-0.8	-0.3	0.0	0.1	-0.1	-0.9	-0.3	-0.6
Medication for cholesterol	0.5	0.7	4.4	-0.3	2.1	-0.9	0.8	1.1	-0.3	-0.9	-1.3	1.0	-0.6	0.2	0.0	0.4	0.6	0.8	0.0	0.9	-0.5	-0.4	0.9	1.1	0.8
Wears glasses or contact lenses	0.5	0.6	2.0	-0.6	0.5	0.6	-1.0	-1.1	-0.5	-0.6	0.7	-1.4	-0.2	-0.8	-0.7	0.3	-1.2	-0.7	-0.5	-0.5	0.3	0.2	-0.9	-1.4	-0.5
Financial situation satisfaction	0.5	0.6	2.3	0.5	-1.4	0.6	-1.1	-1.5	-0.6	-0.8	0.3	-1.1	-0.8	-0.4	0.1	0.3	-0.3	-0.7	-0.4	-0.4	-0.1	0.1	-1.1	-0.8	-0.5
Medication: Blood pressure	0.5	1.0	3.9	-1.2	-2.0	1.6	-0.7	-1.1	2.0	-0.2	-0.4	-1.1	0.2	-0.5	-0.2	1.2	0.3	-0.3	-1.2	0.2	1.8	0.6	-0.4	-0.1	0.1
Risk taking	0.5	0.7	2.1	0.6	-0.4	0.7	1.2	0.6	0.4	-0.2	1.0	0.6	-0.6	1.1	1.2	0.7	0.3	1.0	1.4	0.2	1.2	1.1	1.2	0.0	1.1
Myopia	0.5	0.7	3.9	0.5	-0.4	-1.4	-0.5	-0.6	-1.0	-1.4	0.4	0.4	0.1	-0.2	-0.6	-2.0	-0.3	-0.6	-0.4	-1.1	-0.8	-0.5	-1.2	-0.2	-1.1
Basal cell carcinoma (self-reported)	0.5	0.6	1.8	1.1	0.8	1.2	-1.1	-0.7	-0.2	0.5	-0.6	-0.7	-0.3	-0.1	0.0	-0.6	-0.1	-0.9	-0.6	-1.0	-0.6	-1.3	-1.1	-0.5	-1.0
Leg fat mass (left)	0.5	2.0	11.7	3.4	0.1	-0.4	0.6	0.1	0.1	-0.2	3.3	1.0	-0.4	0.7	1.3	-2.2	-0.6	0.2	2.2	-1.6	-1.8	-1.1	0.2	-0.9	-0.5
Bipolar Disorder (2018)	0.4	0.6	4.3	1.4	0.8	-1.1	0.3	0.4	0.3	0.9	2.1	0.6	0.3	0.7	0.7	-0.2	-0.6	0.4	1.2	-0.4	-0.4	0.7	0.2	-0.3	0.2
Bipolar Disorder or Schizophrenia	0.4	0.9	5.6	1.9	1.1	-0.9	-0.6	-0.7	0.2	-0.0	2.4	-0.1	-0.5	0.3	0.7	-0.4	-0.7	-0.5	1.1	-1.2	-0.3	0.7	-0.8	-0.7	-0.7
Intelligence (Savage-Jansen 2018)	0.4	1.2	3.3	0.4	1.1	0.9	1.3	1.7	-0.3	1.3	-1.8	1.2	1.3	-0.3	0.9	0.8	1.4	1.5	0.3	0.6	1.0	0.3	1.2	0.5	1.5
Verbal and Numeric Reasoning (VNR)	0.4	1.1	5.2	-1.5	1.0	0.2	1.0	1.9	-0.2	0.7	-2.3	0.8	0.6	-1.0	-0.2	0.7	0.8	1.0	-1.2	1.1	0.9	0.2	0.8	0.1	1.2
Prostate Cancer	0.4	0.6	1.6	-0.6	0.5	-0.1	0.7	1.2	0.3	-0.5	-0.4	1.1	-0.6	-0.4	-0.1	1.1	0.7	1.0	-0.3	0.6	1.2	1.0	1.1	0.3	1.2
HDL Cholesterol	0.4	0.7	5.4	-0.8	0.9	1.3	-1.0	-0.7	-0.4	1.4	-1.7	-0.8	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.4	0.9	5.5	0.8	0.1	-0.7	-0.7	-0.7	-0.9	-1.5	0.9	-0.2	-2.4	-0.6	-0.2	-0.8	-0.7	-1.0	0.0	-0.8	-0.7	0.0	-1.4	-1.0	-1.0
Blood Eosinophil Count	0.4	3.0	10.3	1.4	0.3	0.1	-1.9	-2.4	-3.2	0.6	2.5	-2.2	1.5	-0.3	-0.4	-1.8	-1.7	-1.6	-0.4	-2.5	-1.4	-1.9	-1.6	-1.9	-1.9
Type 2 Diabetes (T2D) (2018)	0.4	0.7	4.0	0.5	-0.1	-0.7	-0.7	-1.0	0.8	-1.3	2.0	-0.6	-0.9	0.3	0.3	-0.4	-1.2	-0.7	0.5	-0.6	-0.7	0.3	-0.5	-0.9	-0.8
Systolic blood pressure, automated reading	0.4	1.1	3.7	-1.0	-1.1	-0.6	-0.6	-0.3	-1.2	-1.9	-0.7	-0.4	-1.1	-1.3	-1.5	-1.4	-0.3	-1.1	-1.3	-0.3	-0.9	-1.3	-1.2	-1.0	-1.3
Trunk fat percentage	0.4	1.4	8.9	2.4	0.1	-0.1	0.1	-0.3	-0.4	-0.2	3.0	0.5	-0.9	0.4	0.7	-2.3	-0.3	-0.4	1.5	-0.7	-1.9	-1.1	-0.6	-0.2	-0.9
Average weekly fortified wine intake	0.4	0.4	3.0	-0.7	-1.0	-0.2	-0.2	-0.6	1.3	-1.7	-0.2	-0.3	-0.7	-0.2	-0.6	-0.0	-0.1	-0.3	-0.6	-0.3	0.7	0.5	-0.0	-0.4	-0.3
Hayfever, allergic rhinitis or eczema	0.4	1.0	2.7	-1.1	-0.5	0.3	-1.3	-1.5	-0.9	-1.4	-0.2	-1.6	-0.9	-1.0	-1.1	0.1	-0.9	-1.1	-1.2	-0.1	-0.0	0.4	-1.2	-0.9	-0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	2.7	-0.3	1.2	-0.5	0.1	0.1	0.4	0.3	-1.1	0.1	1.7	-0.8	-0.6	-0.4	0.2	-0.1	-0.7	0.3	-0.7	-0.9	-0.2	0.0	-0.1
Hearing difficulty/problems with background noise	0.4	0.7	3.3	-1.0	0.3	1.1	-0.4	0.3	0.7	-0.2	-1.6	-0.3	0.6	-0.6	-0.2	1.8	-0.1	0.3	-0.9	0.5	1.6	0.1	0.8	-0.1	0.6
Illnesses of siblings	0.4	0.5	2.9	0.3	-0.2	-0.2	0.0	-0.2	-1.1	-0.5	0.5	0.2	-0.6	-0.5	-0.3	-1.7	-0.7	-0.6	0.2	-1.1	-1.2	-1.0	-0.4	-0.7	-0.7
Mouth/teeth dental problems: Dentures	0.4	0.7	2.5	-0.6	1.2	-1.6	1.1	0.5	0.9	-0.7	-0.8	0.5	-0.7	0.1	0.2	1.0	0.9	0.8	0.1	1.2	0.4	0.7	1.1	0.9	0.9
Arm fat mass (right)	0.4	1.5	6.2	2.5	0.5	-0.6	1.5	0.8	1.2	0.1	2.1	1.3	-0.2	1.5	2.0	-1.1	0.9	0.8	2.2	0.5	-0.7	0.1	0.8	0.7	0.3
Gout (self-reported)	0.4	0.6	3.2	0.9	-0.8	0.2	-1.2	-1.8	0.5	-0.9	0.4	-0.9	0.1	-0.2	-0.0	0.5	-0.8	-0.6	0.1	-1.1	-0.0	-0.7	-0.5	-0.9	-0.7
Body fat percentage	0.4	1.5	9.2	2.1	-0.2	-0.3	-0.1	-0.5	-0.8	-0.3	3.0	0.3	-1.1	-0.3	0.3	-2.1	-0.8	-0.5	1.2	-1.4	-1.8	-1.2	-0.6	-1.0	-0.9
Whole body fat mass	0.4	1.9	11.0	3.3	0.4	-0.2	0.9	0.3	0.2	-0.1	3.0	1.2	-0.2	1.3	1.6	-2.2	0.1	0.3	2.2	-0.6	-1.7	-0.9	0.2	-0.0	-0.4
Age at last live birth	0.4	0.6	1.8	-0.4	0.6	0.3	0.9	1.2	0.7	0.1	-1.0	1.1	-1.3	-0.9	-0.2	-1.3	-0.2	0.2	-0.2	-0.4	-0.8	-1.1	0.6	-0.1	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	2.2	-0.6	0.4	0.8	-0.2	-0.4	-0.4	-1.0	-1.5	-0.2	-1.3	-0.8	-0.9	0.1	-0.0	-0.1	-0.7	-0.2	0.5	-0.7	0.2	-0.1	-0.1
Smoking status: Previous	0.4	0.6	2.6	0.3	0.4	-0.8	1.1	1.1	-0.2	1.4	-0.4	0.4	-0.6	0.3	0.0	-0.4	0.9	0.4	0.3	1.6	-0.2	0.4	0.1	1.3	0.4
Diabetes diagnosed by doctor	0.4	0.7	5.6	1.2	0.2	-0.4	-0.0	-0.2	1.1	-0.2	2.4	0.3	0.9	1.2	0.9	-0.3	-0.1	-0.1	1.5	0.2	-0.5	0.5	-0.0	0.0	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.4	-0.9	-0.2	-1.0	-0.2	-0.2	-0.9	-0.5	0.7	-0.9	0.2	-1.2	-0.9	-0.9	-0.7	-0.4	-0.8	-0.5	-0.9	-0.2	0.2	-0.7	-0.4
Breast cancer (self-reported)	0.4	0.5	5.2	0.3	-0.1	2.3	0.5	0.5	1.4	0.5	-0.3	0.7	-0.1	0.7	0.6	-0.4	0.7	0.4	0.1	0.2	0.1	-0.4	0.0	0.6	0.2
Arm fat mass (left)	0.4	1.6	6.7	2.6	0.6	-0.6	1.6	1.0	1.2	0.0	2.2	1.5	-0.2	1.6	1.9	-1.5	0.9	0.8	2.2	0.4	-0.9	-0.0	0.8	0.8	0.2
High cholesterol (Self-reported)	0.4	0.7	1.8	-0.5	-0.8	-0.5	-0.5	0.1	-0.6	0.9	1.3	-0.8	0.3	-0.8	-1.3	-1.1	-1.1	-0.8	-0.7	-0.5	-1.3	-1.1	-0.5	-0.9	-0.9
Ever smoked	0.4	0.7	2.7	1.2	1.7	-0.4	0.9	0.7	0.9	-0.1	0.8	0.3	-0.5	1.2	0.9	-0.1	0.9	0.3	1.3	0.7	0.3	0.9	0.1	0.9	0.2
Number of operations (self-reported)	0.4	0.6	2.9	-1.7	0.4	-0.3	-0.4	-0.7	-1.3	-0.4	0.4	-1.0	0.9	-0.4	-0.7	-0.9	-0.3	-0.8	-1.0	0.2	-0.1	0.2	-0.6	-0.3	-0.9
Unable to work because of sickness or disability	0.4	0.5	2.3	0.1	0.7	-1.5	0.7	0.1	0.5	-0.3	0.8	0.0	-0.0	0.3	0.4	0.4	0.2	0.6	1.4	0.6	0.2	1.4	0.8	0.4	0.6
Commuting to job workplace: Cycle	0.4	0.5	1.7	-1.3	-0.2	-0.4	-0.6	-0.9	-0.2	0.2	-1.0	-0.7	-0.4	-1.3	-1.3	-0.1	-0.1	-0.8	-1.3	-0.2	-0.0	-0.4	-0.5	-0.7	-0.6
Cholesterol lowering medication	0.4	0.7	3.3	0.8	-0.5	-0.8	0.1	0.2	0.7	1.4	1.8	0.5	0.7	-0.1	-0.2	-1.5	-0.6	-0.3	0.5	-0.8	-1.1	-1.0	0.0	-0.5	-0.7
Schizophrenia (2018)	0.3	0.7	2.3	1.4	1.0	-0.3	-1.0	-1.1	-0.7	-0.8	1.5	-0.5	-0.8	-0.3	0.3	-0.4	-0.3	-0.9	0.4	-1.2	-0.2	0.2	-1.2	-0.8	-1.0
Crohns Disease (2017)	0.3	0.6	3.3	0.4	-0.4	-0.3	-1.0	-1.3	-1.0	-1.8	0.0	-1.3	-0.7	-0.1	0.0	0.0	-0.9	-0.7	-0.0	-0.9	-0.4	-0.3	-1.0	-0.4	-0.6
Body Mass Index (BMI) (2010)	0.3	0.4	3.2	-1.8	0.7	-0.5	0.3	0.2	1.1	0.4	-1.5	0.1	-0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.3	2.4	5.7	2.4	2.1	0.7	1.4	1.9	1.0	-0.6	0.8	1.7	0.2	2.2	2.0	0.8	1.9	1.6	2.2	1.9	-0.1	0.0	1.4	2.1	1.3
Smoking Status	0.3	0.7	2.1	1.3	0.2	-0.3	1.0	1.0	0.7	0.3	1.2	0.5	0.4	1.3	1.0	0.1	0.5	0.5	1.5	0.9	0.4	1.2	0.3	0.5	0.5
Chronotype (morning person)	0.3	0.6	2.5	-1.2	0.3	-1.4	0.5	0.0	-0.6	0.5	-0.6	0.5	0.1	-1.4	-0.9	-1.6	0.5	-0.1	-1.1	0.2	-1.3	-0.6	-0.4	-0.2	-0.4
Hearing difficulty/problems: Yes	0.3	0.5	2.6	0.2	0.2	0.6	0.1	-0.0	1.0	-0.0	-0.6	-0.1	0.6	0.0	0.2	1.6	-0.4	0.6	0.5	-0.3	1.4	0.6	1.1	-0.4	0.9
Supplements: Zinc	0.3	0.3	2.2	0.1	-1.5	-0.5	-0.4	-0.5	0.2	0.1	0.7	0.0	-0.6	0.0	-0.3	-0.7	-0.4	-0.4	-0.1	-1.2	-0.4	-0.6	-0.1	-0.2	-0.7
Medication: Metformin	0.3	0.5	2.2	0.7	1.5	0.7	0.3	0.4	0.4	-0.1	0.5	0.5	0.4	0.9	0.9	1.1	-0.0	0.6	1.0	-0.1	0.1	0.1	1.3	-0.3	0.6
Diabetes (mother)	0.3	0.3	2.2	-0.7	-0.4	-1.5	-0.5	-0.1	-0.2	0.3	0.0	-0.0	-0.7	-0.9	-1.0	0.9	-0.3	-0.1	-0.4	-0.3	-0.2	-0.2	-0.0	-0.6	0.1
Past tobacco smoking	0.3	0.5	2.8	-0.7	-0.9	0.6	-0.8	-0.8	-0.4	-0.8	-0.3	-0.1	0.4	-0.9	-0.4	0.0	-0.9	-0.1	-0.7	-1.7	-0.2	-0.9	0.2	-1.3	-0.2
Financial difficulties in last 2 years	0.3	0.4	1.8	-0.0	0.2	-1.3	-0.2	-0.6	0.5	0.0	1.1	-0.8	0.2	-1.0	-0.0	0.0	-0.8	-0.1	0.3	-0.9	-0.6	0.4	0.1	-1.3	0.1
Diabetes (self-reported)	0.3	0.4	2.4	0.6	1.5	-0.5	0.2	0.1	1.6	0.0	0.8	0.5	0.7	0.9	0.6	-0.1	0.2	0.0	1.1	0.5	-0.4	0.3	0.3	0.4	-0.2
Hip circumference	0.3	1.5	7.0	2.6	0.3	-1.1	1.1	0.4	-0.1	-0.2	2.2	1.0	-0.5	0.8	1.2	-2.6	-0.2	0.2	1.6	-0.9	-1.9	-0.9	0.3	-0.4	-0.5
Alcohol intake versus 10 years previously	0.3	0.4	1.9	0.4	0.7	-1.4	-0.5	-0.6	0.1	-1.0	0.2	-0.7	-1.0	-0.6	-0.4	0.3	-0.7	-0.3	0.2	-0.3	-0.6	-0.1	-0.4	-0.8	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	-0.4	0.2	-0.3	-0.6	-0.9	-0.4	-0.8	0.2	-0.9	-0.6	-1.1	-0.8	-0.0	-0.8	-0.5	-0.5	-1.0	-0.7	-0.5	-0.4	-1.2	-0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	3.5	1.9	-0.0	0.5	-0.0	-0.4	0.6	0.9	0.4	-0.6	0.8	1.3	1.1	0.8	0.6	0.2	0.5	0.6	-0.2	0.4	-0.1	0.3	0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	1.4	0.4	-0.0	0.0	0.6	0.6	0.2	0.6	-0.5	0.9	-0.4	0.6	0.9	0.2	1.1	0.5	0.9	0.5	1.0	0.9	0.2	1.2	0.4
Glaucoma (self-reported)	0.3	0.3	0.8	-0.4	0.5	0.8	-0.8	-0.9	-0.1	0.7	-0.1	-0.6	0.4	-0.2	-0.3	-0.3	-0.2	-0.9	-0.5	-0.9	0.0	-0.5	-0.8	-0.4	-0.8
Medication: Amlodipine	0.3	0.4	1.9	-0.6	-1.4	0.0	-0.7	-1.0	0.2	0.6	0.9	-1.1	-0.2	-0.2	-0.8	-0.1	-0.7	-0.9	-0.6	0.0	-0.0	0.0	-0.5	-0.6	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.9	-0.4	1.1	-1.4	-0.0	-0.3	-0.0	0.7	-0.6	-0.0	-0.0	-0.4	-0.7	-0.2	0.2	0.1	-0.5	-0.1	-0.7	-0.9	0.3	-0.0	-0.1
Migraine (self-reported)	0.3	0.3	1.1	-0.8	-0.4	-0.8	-0.3	-0.4	-0.2	-1.0	0.5	-0.6	-0.9	-0.8	-0.4	0.1	-0.2	-0.2	-0.7	-0.0	0.5	0.9	-0.6	-0.4	-0.1
Medication: Aspirin	0.3	0.3	2.3	-1.2	-0.1	-0.6	0.4	-0.0	1.5	0.1	-0.6	-0.2	0.9	-0.8	-0.4	0.3	-0.0	0.1	-0.5	0.2	0.1	0.2	0.8	-0.2	0.2
Illnesses of father: Heart disease	0.3	0.5	2.5	-1.6	1.5	-0.3	0.6	0.8	-0.4	0.5	-0.6	0.2	0.7	-0.7	-0.6	-0.3	0.6	0.2	-0.8	1.0	-0.3	-0.2	0.0	0.4	0.2
Ever had bowel cancer screening	0.3	0.4	2.7	0.5	-0.8	1.3	0.3	0.1	-0.3	0.3	-0.6	0.5	1.6	0.5	0.3	0.6	0.6	0.4	0.1	0.4	0.2	-0.3	0.2	0.3	0.5
Friendships satisfaction	0.3	0.3	2.1	0.4	-0.3	-0.1	-0.6	-0.5	-0.8	0.1	-0.3	-0.6	-1.5	-0.7	-0.1	1.2	-0.6	0.2	-0.3	-0.1	0.1	-0.1	-0.0	-0.2	0.6
Qualifications: nursing, teaching	0.3	0.4	1.0	0.6	0.7	-0.2	0.3	0.3	-0.9	-0.6	-1.0	0.5	0.5	-0.2	0.3	1.0	-0.1	0.6	-0.2	-0.6	-0.4	-0.9	1.0	-0.6	0.8
Commuting to job workplace: Walk	0.3	0.4	2.0	1.1	-0.0	0.4	0.2	-0.3	1.0	-0.9	1.4	-0.1	0.0	0.6	1.0	0.2	-0.5	0.3	0.8	-0.3	-0.1	0.6	0.2	-0.1	0.3
Illnesses of father: None of the above (group 1)	0.3	0.3	1.2	0.4	-0.4	-1.1	-0.4	-0.7	-1.1	-0.3	0.6	-1.1	-1.0	0.1	0.0	-0.1	-0.4	-0.5	-0.0	-0.7	-0.1	0.2	0.2	-0.2	-0.6
Smoking status: Current	0.3	0.5	1.6	1.0	-0.1	0.3	-0.0	-0.3	0.8	-0.7	1.2	0.0	0.8	1.2	1.1	0.6	0.1	0.1	1.0	-0.2	0.9	1.1	0.2	-0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	4.0	-0.7	-2.0	1.0	0.1	0.9	-1.3	0.2	-2.0	0.5	-0.4	0.5	-0.7	-0.2	-0.0	-0.1	-0.8	0.3	-0.3	-0.9	0.2	0.3	-0.2
Average weekly champagne plus white wine intake	0.3	0.5	1.6	-1.2	0.6	-1.1	0.5	0.3	1.3	-0.6	-0.9	0.3	-0.9	-0.8	-0.8	-0.7	-0.1	0.0	-0.6	-0.6	-0.4	-0.3	0.4	-0.6	-0.0
Mother’s age at death	0.3	0.3	1.2	-0.9	-0.1	-1.1	-0.0	0.2	-1.1	-0.7	-0.2	-0.4	-0.5	-0.5	-0.6	-0.7	-0.6	-0.7	-0.4	-0.2	-0.6	-0.3	-0.2	-0.5	-0.7
Eye problems/disorders: Glaucoma	0.3	0.4	1.2	0.3	0.8	0.4	-0.7	-0.8	0.0	1.0	0.8	-0.5	0.9	0.5	0.1	-0.6	-0.2	-1.0	0.1	-0.3	-0.3	-0.5	-0.8	-0.0	-1.1
Diastolic blood pressure, automated reading	0.3	0.8	3.4	0.7	-1.5	1.2	-0.9	-0.9	-1.8	-1.7	-0.3	-0.8	-0.5	-0.4	0.2	-0.4	-0.2	-0.8	-0.2	-1.3	0.0	-0.6	-0.8	-1.0	-0.9
Ever depressed for a whole week	0.3	0.4	2.7	-0.2	-1.2	-0.2	0.2	-0.1	0.3	-1.0	0.0	0.0	-1.7	-0.9	-0.1	-0.0	0.2	0.2	-0.2	-0.6	0.3	0.6	0.3	-0.9	0.2
Supplements: Calcium	0.3	0.3	3.1	-0.2	-0.7	1.8	-0.1	-0.6	0.7	-0.5	-0.9	-0.1	0.4	-0.2	0.0	0.4	-0.1	-0.2	-0.0	0.0	1.1	0.3	-0.2	-0.0	-0.0
Alzheimer’s Disease (in mother)	0.2	0.3	0.7	-0.3	0.0	0.6	-0.7	-0.8	-0.6	0.1	-0.1	-0.0	0.5	0.5	-0.6	-0.6	-0.0	-0.6	-0.4	0.2	-0.4	-0.7	-0.6	0.6	-0.8
BMI	0.2	0.9	3.1	0.7	-0.3	-0.9	-0.5	-1.1	0.3	-1.3	1.3	-0.5	-1.8	-0.8	-0.3	-1.5	-1.0	-0.8	-0.0	-1.1	-1.1	-0.9	-0.8	-1.1	-1.1
Townsend deprivation index at recruitment	0.2	0.3	1.7	-0.6	0.6	-1.3	-0.2	-0.7	-0.1	0.5	0.2	-0.0	-1.1	-1.0	-0.5	0.1	-0.2	-0.0	-0.1	-0.1	0.2	0.3	-0.6	0.2	0.0
Current tobacco smoking	0.2	0.3	0.8	0.8	-0.4	0.2	0.1	-0.2	0.6	-0.5	0.8	0.1	0.7	0.9	0.9	0.6	0.1	0.2	0.9	-0.3	0.8	0.8	0.4	-0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.1	1.5	0.9	-1.3	0.7	0.6	0.2	-0.0	-0.1	0.2	-0.0	1.0	0.8	-0.0	0.4	0.5	0.6	0.7	-1.0	0.1	0.6	0.1	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	2.5	-0.2	0.8	-0.4	-0.5	-0.7	1.6	-0.5	0.4	-0.3	0.3	0.1	0.1	0.6	-0.0	-0.1	0.1	0.1	0.7	0.9	-0.2	0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.2	1.5	0.1	-1.0	0.9	0.8	0.6	0.1	0.1	0.1	0.4	1.2	1.4	0.3	0.3	0.6	0.7	0.7	-0.7	0.4	1.0	-0.0	0.7
Allergy	0.2	0.5	2.2	-0.2	-1.1	0.3	-0.0	0.4	-0.6	1.1	-0.4	0.2	-0.1	0.3	-0.3	-1.5	0.1	-0.7	-0.4	-0.3	-0.9	-1.3	-0.5	0.1	-0.9
Medication: Simvastatin	0.2	0.3	1.8	-0.6	-0.4	-0.2	0.1	0.5	0.3	1.3	0.3	-0.0	0.7	-0.7	-0.5	-0.3	-0.8	0.0	-0.3	-0.4	-0.3	-0.7	0.4	-0.7	0.0
Number of live births	0.2	0.2	1.3	0.2	-0.5	1.1	-0.6	-0.4	0.1	-1.0	0.8	-0.4	0.7	0.1	-0.1	0.4	-0.6	-0.2	-0.3	0.3	0.0	-0.3	-0.5	0.0	0.0
Medication: Cholesterol lowering	0.2	0.4	1.4	-0.8	0.6	-0.2	-0.3	0.0	-0.4	0.0	-0.1	-0.6	0.4	-1.1	-1.0	-0.0	-0.8	-0.2	-0.8	-0.4	-0.7	-0.9	0.2	-1.2	-0.1
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.9	0.1	0.1	-0.7	0.8	0.2	-0.5	-0.9	-1.0	0.1	-0.5	0.1	0.1	0.3	0.8	0.5	-0.0	0.4	-0.0	0.4	0.6	-0.1	0.5
Birth weight	0.2	0.4	2.5	0.9	0.1	0.1	-0.2	-0.0	0.0	1.6	0.1	0.3	1.5	0.8	0.7	0.7	-0.1	0.6	0.3	-0.4	0.4	-0.5	0.3	0.1	0.5
Comparative body size at age 10	0.2	0.7	2.3	-0.1	0.5	-0.7	-1.1	-1.4	-1.5	0.9	-0.4	-1.1	0.4	-0.1	-0.0	-0.9	-0.5	-0.9	-0.8	-0.4	-0.4	-0.2	-1.4	-0.1	-1.2
Age at first live birth	0.2	0.4	1.2	-0.1	1.0	0.8	0.4	1.0	0.3	1.0	-0.7	0.8	0.1	-0.1	-0.2	-0.4	-0.7	0.3	-0.0	-0.3	-0.6	-1.1	0.6	-0.0	0.4
Qualifications: College or University degree	0.2	0.7	2.3	0.3	-0.2	1.5	0.9	0.7	-0.1	0.0	-0.7	0.7	0.8	1.3	1.2	1.0	0.6	1.0	0.3	0.5	1.1	0.7	1.3	0.7	1.1
Family relationship satisfaction	0.2	0.3	1.8	-0.4	0.2	0.6	-0.4	-0.3	0.3	1.4	0.8	-0.2	0.9	-0.3	-0.1	0.7	-0.6	-0.1	-0.1	-0.2	0.5	0.1	-0.0	-0.2	0.2
Illnesses of siblings: Diabetes	0.2	0.3	3.3	0.5	0.2	-1.8	-0.1	-0.1	-0.2	0.3	0.7	0.4	-0.3	-0.1	-0.0	-0.2	-0.6	0.0	0.5	-0.5	-0.6	0.4	0.2	-0.5	-0.1
Medication: Aspirin	0.2	0.3	2.4	-1.0	-0.3	-0.4	0.4	-0.1	1.6	0.2	-0.4	-0.2	0.8	-0.7	-0.2	0.3	-0.0	0.1	-0.4	-0.0	0.2	0.1	0.8	-0.2	0.2
Fractured/broken bones in last 5 years	0.2	0.3	1.1	-0.3	-1.0	0.8	-0.4	0.1	0.6	0.3	-0.5	-0.1	0.5	-0.1	-0.1	0.5	0.4	-0.2	-0.0	0.6	1.0	0.6	-0.7	0.5	-0.1
Impedance of whole body	0.2	1.2	3.5	0.3	-0.7	0.9	-1.6	-1.4	-1.9	-0.7	1.6	-1.1	-1.0	-1.3	-1.1	-0.3	-1.2	-0.9	-0.4	-1.4	-0.7	-0.6	-1.5	-0.8	-0.6
LDL Cholesterol	0.1	0.2	1.1	-0.6	1.1	0.8	-0.2	0.4	0.0	0.0	1.0	-0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.1	0.2	1.6	-0.2	0.4	-0.5	0.2	0.4	-0.0	-0.6	1.3	-0.1	-1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body mass index (BMI)	0.1	0.4	1.6	0.8	0.2	-0.9	0.5	-0.1	0.8	-0.1	1.3	0.3	-1.0	-0.2	0.4	-1.1	-0.2	0.1	0.8	-0.4	-0.7	-0.5	0.2	-0.5	-0.3
Impedance of arm (right)	0.1	0.3	1.5	-0.2	0.3	0.4	0.0	0.0	-1.2	0.2	0.6	0.1	-0.1	-0.3	-0.2	0.8	0.7	0.3	0.4	0.8	-0.1	0.2	-0.0	0.9	0.5
Arm fat percentage (right)	0.1	0.5	3.4	1.1	0.5	-0.8	0.7	0.3	0.3	0.3	1.9	0.6	-0.8	0.0	0.8	-0.8	0.5	0.4	1.3	0.4	-0.5	-0.2	0.3	0.1	0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.8	0.9	-0.2	0.0	-0.1	-0.3	-0.5	0.3	-0.9	0.1	0.4	-0.2	0.1	0.0	-0.0	0.2	-0.3	-0.6	-0.4	-0.5	0.4	-0.6	0.2
Pulse wave Arterial Stiffness index	0.1	0.2	0.8	0.9	0.1	-0.6	0.1	0.4	-0.7	-0.4	-0.3	0.3	0.2	0.0	0.2	-0.8	-0.0	-0.0	0.5	-0.3	-0.6	-0.0	-0.3	0.3	-0.2
Pulse wave peak to peak time	0.1	0.1	0.5	-0.2	0.2	0.5	0.3	-0.1	0.7	0.4	0.7	0.1	0.2	0.6	0.3	0.3	0.3	0.2	-0.0	0.4	0.3	0.1	0.4	0.1	0.2
Arm fat percentage (left)	0.1	0.5	3.5	1.0	0.4	-0.6	0.7	0.3	0.2	-0.0	1.9	0.7	-1.0	-0.1	0.7	-1.0	0.3	0.3	1.2	0.1	-0.7	-0.4	0.3	-0.0	-0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Impedance of arm (left)	0.0	0.2	1.3	-0.5	0.1	0.5	-0.3	-0.2	-1.1	-0.1	0.5	-0.1	-0.3	-0.4	-0.5	0.4	0.4	-0.1	-0.1	0.8	-0.3	0.0	-0.4	0.8	0.1

Hub : Genes

CTU2

Models

Trait associations