TWAS hub - ALOXE3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0407	0.0182	0.0055	0.000	0.008	-0.001	NA	-0.002	0.31000	3.4e-02	0.48000	NA	0.6900
2	TCGA	Pancreatic Adenocarcinoma	0.2020	0.0740	0.0028	0.069	0.114	0.095	NA	0.043	0.00077	1.7e-05	0.00009	NA	0.0065

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Depression (self-reported)	6.4	7.7	10.1	3.2	2.3
Chronotype (morning person)	5.7	13.2	17.5	3.0	4.2
Standing height	5.1	51.0	76.9	-8.8	-5.0
Comparative height size at age 10	4.9	27.2	47.1	-6.9	-2.7
Verbal and Numeric Reasoning (VNR)	4.8	11.5	19.5	-4.4	-1.9
Exposure to tobacco smoke outside home	4.8	6.4	11.6	1.1	3.4
Qualifications: CSEs or equivalent	4.4	5.7	11.3	3.4	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	4.3	5.7	9.8	1.2	3.1
Medication: Lansoprazole	4.3	4.9	8.4	2.9	1.2
Forced expiratory volume in 1-second (FEV1), predicted	4.2	8.7	8.9	-3.0	-2.9
Heart disease (siblings)	4.2	5.2	8.3	1.4	2.9
Ever unenthusiastic/disinterested for a whole week	4.1	5.0	9.7	3.1	0.6
Ever highly irritable/argumentative for 2 days	4.1	4.9	5.5	2.3	2.1
Trunk predicted mass	3.9	22.1	36.4	-6.0	-2.8
Trunk fat-free mass	3.8	21.7	35.5	-6.0	-2.8
Height	3.7	71.8	106.1	-10.3	-6.1
Fluid intelligence score	3.7	7.7	8.9	-3.0	-2.6
Arm predicted mass (left)	3.6	18.3	30.7	-5.5	-2.4
Medication: Aspirin	3.5	4.6	8.3	1.0	2.9
Whole body fat-free mass	3.4	19.5	32.4	-5.7	-2.6
Whole body water mass	3.3	19.1	31.2	-5.6	-2.6
Arm fat-free mass (left)	3.3	16.6	27.6	-5.2	-2.4
Medication: Ibuprofen (e.g. Nurofen)	3.2	4.1	8.1	2.9	-0.1
Basal metabolic rate	3.2	17.4	29.3	-5.4	-2.4
Depression (Nagel 2018)	3.1	4.7	7.4	1.4	2.7
Noisy workplace	3.0	3.7	6.7	2.6	0.9
Pain type(s) experienced in last month: Hip pain	3.0	3.8	7.3	2.7	-0.6
Average weekly fortified wine intake	2.9	3.4	5.7	1.0	-2.4
Tinnitus: Yes, but not now, but have in the past	2.9	3.1	6.2	2.5	0.1
Sitting height	2.9	20.3	37.6	-6.1	-1.8
Chest pain or discomfort	2.9	4.1	7.2	-1.1	2.7
Leg predicted mass (right)	2.9	15.3	24.6	-5.0	-2.4
Leg fat-free mass (right)	2.8	15.0	24.8	-5.0	-2.3
Leg predicted mass (left)	2.7	14.4	24.5	-5.0	-2.0
Arm predicted mass (right)	2.7	14.0	24.4	-4.9	-1.9
Prospective memory result	2.6	3.2	3.6	1.7	1.9
Arm fat-free mass (right)	2.6	13.3	23.3	-4.8	-1.8
Medication: Aspirin	2.6	3.4	6.2	0.7	2.5
Leg fat-free mass (left)	2.5	13.5	22.9	-4.8	-2.0
Medication for pain relief, constipation, heartburn	2.5	4.2	8.2	-2.9	-0.5
Weight	2.3	11.5	19.8	-4.5	-1.8
Financial situation satisfaction	2.3	2.9	5.8	-0.1	2.4
Frequency of depressed mood in last 2 weeks	2.2	3.1	4.9	1.2	2.2
Number of full brothers	2.2	2.8	4.5	1.0	2.1
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.5	5.4	1.2	2.3
Qualifications: O levels/GCSEs or equivalent	2.1	3.3	6.2	-2.5	-0.7
Qualifications: College or University degree	2.1	6.7	9.1	-3.0	-2.0
Ever taken oral contraceptive pill	2.1	2.4	3.5	1.9	1.1
Ever had prostate specific antigen (PSA) test	2.1	2.4	2.5	-1.6	1.5
Alzheimer’s Disease (in mother)	2.0	2.3	4.5	2.1	0.3
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.2	6.3	0.1	2.5
Hearing difficulty/problems with background noise	2.0	3.3	3.3	1.8	-1.8
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	4.4	-2.1	-0.5
Intelligence (Savage-Jansen 2018)	1.9	6.0	10.6	-3.3	-1.2
Schizophrenia vs Biploar Disorder	1.9	2.5	5.1	2.3	0.1
Lupus	1.9	2.8	4.9	0.8	2.2
Mood swings	1.9	3.5	5.2	-1.4	2.3
Blood Eosinophil Count	1.8	13.9	27.6	-5.2	0.4
Lung FVC	1.8	9.2	10.4	3.2	2.8
Vitamin and mineral supplements	1.8	2.4	4.6	2.1	-0.6
Leg pain on walking	1.8	2.2	2.3	1.5	1.5
Risk taking	1.8	2.6	3.8	1.2	1.9
Fasting Glucose	1.7	2.0	2.6	-1.2	1.6
Hayfever, allergic rhinitis or eczema	1.7	3.7	6.7	0.8	2.6
Number of live births	1.7	2.4	4.9	2.2	0.1
Exposure to tobacco smoke at home	1.7	1.9	3.5	0.6	1.9
Shortness of breath walking on level ground	1.7	2.0	3.3	0.8	1.8
Medication: Ibuprofen	1.7	2.1	3.5	1.9	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	2.9	1.7	-1.1
Supplements: Calcium	1.7	1.9	3.7	0.2	1.9
Relative age of first facial hair	1.6	3.3	4.4	-1.5	-2.1
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	3.2	-0.7	-1.8
Alzheimer’s Disease (including proxy)	1.5	2.2	4.3	2.1	-0.2
Ulcerative Colitis	1.5	2.2	3.3	1.8	-1.0
Qualifications: None of the above	1.5	3.1	6.2	2.5	-0.3
Father’s age at death	1.5	2.0	3.2	-0.9	-1.8
Mouth/teeth dental problems: Bleeding gums	1.5	2.0	2.5	1.2	1.6
Pulse rate, automated reading	1.5	4.7	9.5	-3.1	0.0
Medication: Gliclazide	1.5	1.6	3.3	1.8	0.1
Unable to work because of sickness or disability	1.5	2.0	3.7	1.9	0.5
Allergy or Eczema	1.4	3.6	3.6	1.9	1.9
Birth weight of first child	1.4	2.6	4.5	-0.8	-2.1
Neck or shoulder pain in last month	1.4	2.0	2.1	1.4	1.4
Body Mass Index (BMI) (2010)	1.3	1.8	3.6	-1.9	0.2
Supplements: Zinc	1.3	1.4	1.8	-1.0	1.3
Medication: Co-codamol	1.3	1.5	3.1	-0.1	1.8
Mouth/teeth dental problems	1.3	2.0	3.5	-0.8	-1.9
Allergy	1.3	3.1	6.0	-0.5	-2.4
Falls in the last year	1.3	1.8	2.1	1.4	-1.2
Loud music exposure frequency	1.3	1.4	1.8	1.3	-1.0
Eye problems/disorders: Cataract	1.3	1.5	1.6	-1.3	-1.1
Commuting to job workplace: Public transport	1.3	1.5	2.4	-1.6	-0.8
Number of treatments/medications taken	1.2	2.1	3.1	1.8	1.1
Multivitamins +/- minerals	1.2	1.5	2.5	-1.6	0.8
Qualifications: A levels/AS levels or equivalent	1.2	2.7	4.2	-2.0	-1.1
Illnesses of mother	1.2	1.5	2.1	-1.4	-0.9
Number of children fathered	1.2	1.3	1.8	1.3	-0.9
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.7	-0.3	1.6
Illnesses of siblings: Diabetes	1.2	1.4	2.7	0.4	-1.6
Handedness (chirality/laterality): Left-handed	1.2	1.4	2.9	1.7	-0.1
Reaction Time	1.1	2.1	4.2	2.0	-0.1
Diabetes (father)	1.1	1.3	2.5	1.6	0.4
Financial difficulties in last 2 years	1.1	1.5	1.6	1.2	1.3
Pulse rate	1.1	1.8	2.8	-1.7	0.9
Blood clot in the leg (DVT)	1.1	1.5	2.4	-1.6	0.7
Glaucoma (self-reported)	1.1	1.3	2.6	-1.6	-0.0
Ever had bowel cancer screening	1.1	1.3	2.3	-1.5	0.5
Irritability	1.1	1.8	3.0	-1.7	0.8
Schizophrenia (2018)	1.0	2.0	4.1	2.0	0.0
Alzheimer’s Disease (in father)	1.0	1.1	2.1	1.4	-0.3
Blood Red Count	1.0	10.0	17.6	1.6	4.2
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.0	-0.6	1.4
Trunk fat mass	1.0	4.1	7.1	-2.7	-1.1
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	1.4	1.2	1.1
Illnesses of siblings	1.0	1.5	2.5	-0.7	-1.6
Happiness	1.0	1.2	2.2	-1.5	0.5
Length of working week for main job	1.0	1.1	1.5	1.2	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	3.0	0.1	1.7
Migraine (self-reported)	1.0	1.2	2.2	1.5	0.5
Knee pain experienced in last month	1.0	1.6	3.2	1.8	0.0
Smoking status: Previous	1.0	1.4	2.8	1.7	-0.4
Osteoarthritis (self-reported)	1.0	1.3	2.1	-1.4	-0.7
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	1.5	-1.0	1.2
Pack years of smoking	1.0	1.4	2.9	0.1	1.7
Fed-up feelings	0.9	1.6	2.2	-1.5	1.0
Taking other prescription medications	0.9	1.4	2.5	0.5	1.6
Neuroticism score	0.9	1.9	2.6	-1.6	1.1
Hip circumference	0.9	3.7	7.0	-2.6	-0.7
Headache pain in last month	0.9	1.5	2.6	1.6	0.7
Medication: Ventolin 100micrograms inhaler	0.9	1.2	1.4	-0.9	-1.2
Worry too long after embarrassment	0.9	1.5	2.6	-1.6	-0.6
Health satisfaction	0.9	1.1	2.2	1.5	0.2
Overall health rating	0.9	2.0	3.6	0.5	1.9
Commuting to job workplace: Car/motor vehicle	0.9	1.0	1.9	1.4	0.4
Back pain experienced in last month	0.9	1.3	2.7	-1.6	0.2
Average weekly spirits intake	0.8	1.0	1.8	1.3	-0.5
Hearing difficulty/problems: Yes	0.8	1.3	2.5	0.4	-1.6
Pack years adult smoking proportion	0.8	1.2	2.4	-0.0	1.5
Medication for cholesterol, blood pressure or diabetes	0.8	1.2	2.0	1.4	-0.7
Gout (self-reported)	0.8	1.0	1.8	0.5	1.4
Age at last live birth	0.8	1.1	2.2	0.1	-1.5
Friendships satisfaction	0.8	1.0	2.1	0.1	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	3.1	1.8	-0.6
Number of self-reported non-cancer illnesses	0.8	1.4	2.6	0.3	1.6
Miserableness	0.8	1.4	1.7	-1.3	1.0
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.0	-1.4	-0.1
Medication: Paracetamol	0.8	1.3	2.5	1.6	0.1
Mean Putamen Volume	0.7	0.8	1.5	-1.2	-0.4
Heel T-Score	0.7	5.4	9.7	3.1	-1.1
Smoking Status	0.7	1.6	2.0	1.1	1.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.0	1.0	0.9
Hand grip strength (right)	0.7	2.0	3.9	-2.0	-0.4
Relative age voice broke	0.7	1.1	1.4	-0.9	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	2.6	1.6	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	2.6	1.6	-0.8
Alcohol intake versus 10 years previously	0.7	1.0	1.0	1.0	-1.0
Medication: Allopurinol	0.7	1.0	2.0	-0.2	1.4
Mean time to correctly identify matches	0.7	1.3	1.5	1.2	-1.1
Whole body fat mass	0.7	3.0	5.5	-2.3	-0.7
Family relationship satisfaction	0.7	0.8	1.6	-0.3	-1.3
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.7	1.3	0.2
Breast cancer (self-reported)	0.7	0.8	1.5	0.3	-1.2
Smoking status: Current	0.7	1.2	2.3	-0.3	1.5
Arm fat mass (left)	0.7	3.0	5.8	-2.4	-0.3
Wears glasses or contact lenses	0.7	0.8	1.3	-1.2	0.5
Hearing aid user	0.7	0.8	1.3	0.5	1.1
Eye problems/disorders: Glaucoma	0.7	0.9	1.7	-1.3	-0.2
Medication: Atorvastatin	0.7	0.8	1.1	-0.7	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	1.1	0.8	1.1
Crohns Disease (2017)	0.6	1.2	2.4	-0.2	-1.6
Crohns Disease (2012)	0.6	1.0	2.0	0.3	-1.4
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.3	1.1	0.2
Hand grip strength (left)	0.6	1.5	2.2	-1.5	-0.9
Current tobacco smoking	0.6	0.9	1.6	-0.5	1.3
Hair/balding pattern: Pattern 2	0.6	0.8	0.8	0.9	0.9
Medication: Ramipril	0.6	0.7	1.3	1.1	0.4
Arm fat mass (right)	0.6	2.4	4.4	-2.1	-0.6
Hair/balding pattern: Pattern 4	0.6	1.5	2.6	-0.6	-1.6
Pulse wave reflection index	0.6	0.8	1.4	1.2	0.4
Medication: Paracetamol	0.6	0.9	1.7	1.3	-0.4
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	1.8	-0.6	1.3
Diabetes diagnosed by doctor	0.6	0.9	1.6	-1.3	0.5
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.3	-1.1	0.4
Medication: Bendroflumethiazide	0.6	0.9	1.2	-0.8	-1.1
Ever smoked	0.6	1.0	1.8	1.3	0.5
Diastolic blood pressure, automated reading	0.6	1.9	3.0	-0.8	1.7
Commuting to job workplace: Cycle	0.6	0.7	1.2	-1.1	0.5
HbA1C	0.5	0.6	1.2	-0.0	1.1
Schizophrenia (2014)	0.5	1.1	2.1	1.5	0.1
Cardiovascular Disease	0.5	1.6	3.0	-0.4	1.7
Hypothyroidism (self reported)	0.5	1.2	1.3	-1.1	1.0
Systolic blood pressure, automated reading	0.5	1.5	2.2	-1.5	0.9
Maternal smoking around birth	0.5	0.7	1.3	-0.1	1.2
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.1	-1.0	0.0
High blood pressure (mother)	0.5	0.8	1.5	-1.2	-0.1
Past tobacco smoking	0.5	0.8	1.7	-1.3	0.1
Worrier / anxious feelings	0.5	0.9	1.6	-0.4	1.3
Medication: Amlodipine	0.5	0.7	1.2	-0.4	-1.1
Birth weight	0.5	1.1	1.8	-1.4	-0.7
Wheeze or whistling in the chest in last year	0.5	0.9	0.9	-1.0	1.0
Age at first live birth	0.5	0.8	1.3	-0.6	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.1	0.3	1.0
Average weekly red wine intake	0.5	0.8	1.0	0.8	-1.0
Qualifications: nursing, teaching	0.5	0.7	1.2	-0.5	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	0.9	0.9	0.9
High cholesterol (Self-reported)	0.5	0.9	1.8	-0.2	1.3
Fractured/broken bones in last 5 years	0.5	0.6	1.3	-1.1	0.1
Bipolar Disorder (2018)	0.4	0.7	1.2	-0.4	-1.1
Bipolar Disorder or Schizophrenia	0.4	1.0	1.5	1.2	-0.8
Waist Hip Ratio (WHR)	0.4	1.9	2.2	1.2	-1.5
Neuroticism	0.4	1.1	1.9	-1.4	0.5
Severe depression (siblings)	0.4	0.4	0.9	0.0	0.9
Age when periods started (menarche)	0.4	1.0	1.7	-0.6	1.3
Supplements: Glucosamine	0.4	0.5	0.9	-0.4	-0.9
Had other major operations	0.4	0.5	0.8	-0.9	-0.4
Medication: Simvastatin	0.4	0.6	0.8	0.9	0.6
Chronic bronchitis/emphysema (mother)	0.4	0.4	0.8	0.9	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.0	0.3	1.0
Eye problems/disorders: None of the above	0.4	0.5	0.6	0.6	0.8
Medication: Omeprazole	0.4	0.5	1.0	0.1	1.0
Medication: Seretide 50 evohaler	0.4	0.5	0.9	-0.9	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.7	-0.9	0.5
Leg fat mass (right)	0.4	1.7	3.3	-1.8	-0.4
Number of full sisters	0.4	0.5	0.9	0.3	0.9
Had major operations	0.4	0.4	0.7	-0.4	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.6	0.8	0.6
Medication for cholesterol	0.4	0.6	1.2	-0.3	-1.1
Mineral and other dietary supplements	0.4	0.6	0.8	0.9	0.6
Guilty feelings	0.4	0.6	0.7	-0.8	0.7
Illnesses of father: High blood pressure	0.4	0.5	1.0	0.0	1.0
Alcohol drinker status: Never	0.4	0.5	1.0	-1.0	-0.2
Average weekly beer plus cider intake	0.4	0.5	0.7	0.9	0.5
Age started oral contraceptive pill	0.4	0.5	0.6	-0.7	0.8
Pain experienced in last month	0.4	0.7	1.1	-1.0	-0.5
Leg fat mass (left)	0.4	1.6	3.0	-1.7	-0.4
Depressed Affect (Nagel 2018)	0.3	0.6	0.6	-0.8	0.7
Irritable Bowel Disease (IBD)	0.3	0.7	1.3	0.4	-1.1
Age at First Birth	0.3	0.4	0.7	-0.8	-0.3
Primary Biliary Cirrhosis	0.3	0.4	0.7	-0.4	-0.9
Type 2 Diabetes (T2D) (2018)	0.3	0.6	0.9	-0.9	-0.6
Angina	0.3	0.4	0.7	0.9	-0.4
Diabetes (mother)	0.3	0.4	0.8	-0.1	-0.9
Serious illness, injury or assault to yourself	0.3	0.3	0.4	-0.5	-0.6
High blood pressure	0.3	0.9	1.1	-1.1	0.8
Medication: Atenolol	0.3	0.3	0.4	0.5	-0.6
Chronic bronchitis/emphysema (father)	0.3	0.3	0.6	0.1	-0.8
Waist circumference	0.3	1.0	1.3	-1.1	-0.9
Number of incorrect matches in round	0.3	0.5	0.9	1.0	-0.3
Forced vital capacity (FVC)	0.3	1.1	1.8	-1.3	-0.6
Pain all over the body in last month	0.3	0.4	0.4	0.6	0.6
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	1.3	-1.1	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.1	-0.9	-1.1
Pulse wave peak to peak time	0.3	0.4	0.4	-0.6	-0.6
Emphysema/chronic bronchitis	0.3	0.3	0.6	-0.8	0.1
Hypertension (Self-reported)	0.3	0.9	1.1	-1.0	0.9
Loneliness, isolation	0.3	0.4	0.6	-0.8	0.5
Long-standing illness, disability or infirmity	0.3	0.5	0.9	0.3	1.0
Osteoporosis (self-reported)	0.3	0.4	0.4	0.6	0.6
Illnesses of father: None of the above (group 1)	0.3	0.4	0.8	-0.9	0.3
Worry (Nagel 2018)	0.2	0.4	0.6	0.5	0.8
Ulcerative Colitis (UC)	0.2	0.3	0.6	0.8	-0.2
Breast Cancer	0.2	0.4	0.9	0.9	-0.0
Ovarian Cancer	0.2	0.3	0.4	0.4	0.6
Neuroticism (2016)	0.2	0.3	0.4	0.5	-0.6
Rheumatoid Arthritis	0.2	0.2	0.5	0.7	-0.1
Triglycerides	0.2	0.3	0.3	-0.6	-0.5
Blood White Count	0.2	1.1	1.8	-0.7	1.3
Systolic Blood Pressure	0.2	0.9	1.7	0.4	1.3
Lung FEV1/FVC ratio	0.2	1.0	1.8	-1.4	0.3
Medication for hormone replacement therapy	0.2	0.2	0.4	0.6	0.2
Medication: Metformin	0.2	0.3	0.4	-0.4	-0.6
Trunk fat percentage	0.2	1.0	1.9	-1.4	-0.2
Townsend deprivation index at recruitment	0.2	0.3	0.5	0.2	0.7
Stomach or abdominal pain in last month	0.2	0.3	0.3	0.6	0.4
Medication: Levothyroxine sodium	0.2	0.3	0.4	-0.5	0.7
Nervous feelings	0.2	0.3	0.4	0.5	0.6
Asthma	0.2	0.3	0.6	0.1	0.8
Medication: Cholesterol lowering	0.2	0.3	0.4	-0.4	0.6
Tense / ‘highly strung’	0.2	0.3	0.6	0.2	0.8
Peak expiratory flow (PEF)	0.2	0.4	0.7	-0.9	0.2
Forced vital capacity (FVC), Best measure	0.2	0.6	0.6	-0.8	-0.7
Medication: Blood pressure	0.2	0.3	0.5	-0.7	0.4
Angina (self-reported)	0.2	0.3	0.6	0.8	-0.1
Heart disease (mother)	0.2	0.3	0.3	0.6	-0.4
Suffer from ‘nerves’	0.2	0.4	0.7	0.0	-0.8
Illnesses of father: Heart disease	0.2	0.2	0.5	-0.1	-0.7
Commuting to job workplace: Walk	0.2	0.2	0.2	0.4	0.4
Mother’s age at death	0.2	0.3	0.4	-0.6	-0.4
Medication: Lisinopril	0.2	0.2	0.5	0.7	0.1
Vascular/heart problems diagnosed by doctor	0.2	0.4	0.5	0.6	-0.7
Alcohol drinker status: Previous	0.2	0.2	0.3	0.5	0.4
Neuroticism (Nagel 2018)	0.1	0.2	0.3	-0.2	0.5
HDL Cholesterol	0.1	0.1	0.2	0.3	-0.4
LDL Cholesterol	0.1	0.1	0.2	-0.4	-0.2
Blood Platelet Count	0.1	1.1	1.8	1.3	0.6
BMI	0.1	0.7	1.2	0.3	1.1
Respiratory disease	0.1	0.2	0.4	0.6	0.1
Tanning	0.1	1.7	3.2	-0.4	-1.8
Sensitivity / hurt feelings	0.1	0.2	0.3	0.6	0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.2	0.5	0.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.2	-0.5	-0.3
Impedance of leg (right)	0.1	0.4	0.7	0.3	0.9
Body mass index (BMI)	0.1	0.3	0.4	-0.4	0.6
Had menopause	0.1	0.2	0.2	0.3	-0.5
Heart attack	0.1	0.1	0.2	0.3	0.4
Diabetes (self-reported)	0.1	0.1	0.3	-0.5	-0.0
Impedance of arm (right)	0.1	0.4	0.4	-0.5	-0.7
Arm fat percentage (right)	0.1	0.4	0.8	-0.9	-0.3
Time employed in main current job	0.1	0.2	0.3	-0.0	0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	0.6	-0.2
Lung cancer (father)	0.1	0.1	0.2	-0.4	-0.0
Breastfed as a baby	0.1	0.1	0.2	-0.1	0.5
High blood pressure (siblings)	0.1	0.2	0.3	0.1	0.5
Body fat percentage	0.1	0.4	0.9	-0.9	0.1
Leg fat percentage (right)	0.1	0.3	0.4	-0.5	0.6
Comparative body size at age 10	0.1	0.4	0.5	-0.7	-0.5
Alcohol intake frequency.	0.1	0.3	0.6	-0.1	0.7
Supplements: Vitamin C	0.1	0.1	0.2	-0.5	-0.3
Arm fat percentage (left)	0.1	0.3	0.4	-0.7	0.2
Asthma (self-reported)	0.1	0.1	0.1	0.3	0.4
Average weekly champagne plus white wine intake	0.1	0.2	0.3	-0.6	0.2
Medication: Blood pressure	0.1	0.1	0.1	-0.3	0.4
Leg fat percentage (left)	0.1	0.2	0.2	-0.5	0.4
Number of operations (self-reported)	0.1	0.1	0.3	-0.5	0.0
Ever depressed for a whole week	0.1	0.2	0.3	0.6	-0.1
Myopia	0.1	0.2	0.3	-0.2	0.6
Cholesterol lowering medication	0.1	0.1	0.3	0.5	0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	-0.1	-0.5
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.2	0.5	0.3
Major Depression (MDD)	0.0	0.0	0.0	0.2	-0.0
Prostate Cancer	0.0	0.0	0.0	-0.1	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.1	0.1	0.3	0.2
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	0.2	-0.0
Impedance of leg (left)	0.0	0.2	0.2	0.4	0.5
Alcohol usually taken with meals	0.0	0.1	0.1	0.3	-0.2
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	0.1	0.0
Pulse wave Arterial Stiffness index	0.0	0.0	0.0	0.1	0.2
Impedance of arm (left)	0.0	0.1	0.1	-0.4	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.1	-0.0
Impedance of whole body	0.0	0.1	0.1	0.2	0.2

Hub : Genes

ALOXE3

Models

Trait associations