TWAS hub - TRAPPC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Pancreas	0.173	0.064	0.00160	-0.001	NA	0.004	NA	0.007	0.3700	NA	2.2e-01	NA	1.5e-01
2	TCGA	Thyroid Carcinoma	0.122	0.059	0.00027	0.025	0.02	0.045	NA	0.046	0.0017	0.004	3.4e-05	NA	2.6e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Height	9.4	181.5	334.9	18.3	5.3
Standing height	8.6	85.2	156.2	12.5	3.8
Sitting height	7.8	55.1	106.1	10.3	2.0
Mother’s age at death	7.8	9.8	16.6	4.1	1.7
Deep venous thrombosis (DVT) (self-reported)	6.7	8.6	15.8	-4.0	-1.2
Blood clot in the leg (DVT)	6.3	8.2	14.4	-3.8	-1.4
Alcohol usually taken with meals	6.2	10.0	18.3	4.3	1.3
Lung FVC	5.9	29.9	53.4	-7.3	-2.5
Blood Red Count	5.8	56.1	71.2	-8.4	-6.4
Qualifications: CSEs or equivalent	5.5	7.2	14.0	-3.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted	5.2	10.9	20.5	4.5	1.1
Diabetes (mother)	4.9	6.2	8.8	-1.9	-3.0
Medication: Bendroflumethiazide	4.9	7.5	14.9	-3.9	-0.1
Alcohol drinker status: Never	4.9	5.8	9.5	-3.1	-1.5
Myopia	4.6	6.6	13.2	0.3	-3.6
Prospective memory result	4.5	5.5	8.8	-3.0	-1.5
Wears glasses or contact lenses	4.1	4.7	7.2	2.7	1.5
Frequency of tiredness / lethargy in last 2 weeks	4.0	6.5	12.5	-3.5	-0.7
Average weekly red wine intake	4.0	5.9	8.7	2.9	1.8
Cholesterol lowering medication	3.9	5.7	8.4	-2.9	-1.8
Frequency of depressed mood in last 2 weeks	3.7	5.2	10.3	-3.2	-0.2
Miserableness	3.6	6.3	9.2	-3.0	-1.8
Depression (Nagel 2018)	3.5	5.3	10.4	-3.2	0.3
Commuting to job workplace: Public transport	3.5	4.2	6.2	2.5	1.5
Systolic Blood Pressure	3.4	17.2	32.6	-5.7	-1.3
Trunk fat-free mass	3.4	19.4	38.8	6.2	-0.0
Trunk predicted mass	3.4	19.5	38.9	6.2	0.0
Medication: Paracetamol	3.4	5.7	11.2	-3.4	-0.3
Medication: Amlodipine	3.4	4.7	9.2	-3.0	-0.5
Comparative height size at age 10	3.4	18.7	33.9	5.8	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	3.3	4.3	8.2	-2.9	-0.7
Taking other prescription medications	3.3	5.1	5.5	-2.2	-2.4
Qualifications: A levels/AS levels or equivalent	3.1	6.9	13.8	3.7	0.2
Birth weight of first child	3.1	5.7	10.2	3.2	-1.1
Blood Platelet Count	3.0	34.6	61.6	-2.8	-7.8
Medication: Levothyroxine sodium	3.0	5.1	9.8	-0.7	-3.1
Medication: Blood pressure	3.0	5.8	10.8	-3.3	-0.9
Fractured/broken bones in last 5 years	3.0	3.9	7.9	2.8	-0.0
Commuting to job workplace: Walk	2.9	3.2	4.3	2.1	1.4
High blood pressure (siblings)	2.8	4.0	7.7	-2.8	-0.5
Medication for pain relief, constipation, heartburn	2.8	4.7	9.3	3.0	-0.4
Alcohol intake frequency.	2.8	6.6	11.4	-3.4	-1.4
Age when periods started (menarche)	2.7	6.5	9.9	-1.7	-3.2
Tense / ‘highly strung’	2.7	4.5	6.5	-2.5	-1.6
Number of treatments/medications taken	2.6	4.6	8.9	-3.0	0.6
Qualifications: College or University degree	2.6	8.3	16.5	4.1	-0.3
High cholesterol (Self-reported)	2.6	4.6	8.8	-3.0	0.5
Blood Eosinophil Count	2.5	19.0	30.0	-2.8	-5.5
BMI	2.5	14.5	21.8	-4.7	-2.7
Medication: Blood pressure	2.5	4.5	5.0	-2.0	2.2
Illnesses of siblings: Diabetes	2.5	3.1	4.7	-2.2	-1.2
Osteoarthritis (self-reported)	2.5	3.3	6.0	0.8	2.4
Number of self-reported non-cancer illnesses	2.5	4.3	8.4	-2.9	0.4
Leg fat percentage (left)	2.5	9.0	15.1	-3.9	-1.7
Alzheimer’s Disease (in mother)	2.4	2.8	3.8	1.3	2.0
Schizophrenia (2014)	2.4	5.3	6.6	2.0	2.6
Chronotype (morning person)	2.4	5.6	7.5	-2.7	-1.9
Sensitivity / hurt feelings	2.4	4.1	6.6	-2.6	-1.3
Body mass index (BMI)	2.4	10.3	16.7	-4.1	-2.0
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	7.3	-2.7	0.2
Whole body fat-free mass	2.4	13.6	27.2	5.2	0.0
Medication for cholesterol	2.4	3.7	5.4	2.3	1.4
Hypothyroidism (self reported)	2.3	5.3	10.5	0.3	-3.2
Serious illness, injury or assault of a close relative in last 2 years	2.3	2.6	4.5	-0.9	-2.1
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	4.5	1.7	-2.1
Hypertension (Self-reported)	2.3	6.3	9.7	-3.1	1.7
Whole body water mass	2.3	13.1	26.2	5.1	-0.0
Arm predicted mass (left)	2.3	11.6	22.2	4.7	-1.0
Smoking Status	2.2	5.2	10.0	-0.6	3.2
Current tobacco smoking	2.2	3.6	6.8	-0.7	2.6
Fed-up feelings	2.2	3.9	7.3	-2.7	-0.7
Mouth/teeth dental problems: Bleeding gums	2.2	2.9	4.2	-2.0	-1.3
Leg fat percentage (right)	2.2	8.1	14.1	-3.8	-1.4
Fasting Glucose	2.1	2.5	4.8	0.5	-2.2
Cardiovascular Disease	2.1	6.9	10.2	-3.2	1.9
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	3.6	1.0	1.9
Medication: Co-codamol	2.1	2.4	2.6	-1.6	-1.5
Hand grip strength (right)	2.1	5.7	11.4	3.4	-0.2
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	5.0	-0.3	2.2
Illnesses of siblings	2.1	3.0	4.9	2.2	1.0
Neuroticism score	2.1	4.3	8.2	-2.9	-0.6
Arm fat percentage (left)	2.1	8.4	16.7	-4.1	-0.3
Ever smoked	2.1	3.7	5.8	1.3	2.4
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	4.2	2.0	0.7
High blood pressure	2.0	5.5	8.3	-2.9	1.6
Exposure to tobacco smoke at home	2.0	2.3	3.4	-1.8	1.1
Number of full brothers	2.0	2.5	4.0	-2.0	-1.0
Number of children fathered	2.0	2.2	2.5	1.4	1.6
Handedness (chirality/laterality): Left-handed	2.0	2.5	4.2	-2.1	-0.8
Qualifications: nursing, teaching	2.0	3.2	6.2	2.5	0.5
Illnesses of father: High blood pressure	2.0	2.5	5.0	-2.2	0.1
Arm fat-free mass (left)	2.0	10.2	19.5	4.4	-0.9
Unable to work because of sickness or disability	2.0	2.5	3.5	-1.9	-1.3
Body Mass Index (BMI) (2010)	1.9	2.6	3.1	-1.4	-1.8
Waist Hip Ratio (WHR)	1.9	8.5	12.8	3.6	2.0
Respiratory disease	1.9	4.2	7.4	2.7	1.0
High blood pressure (mother)	1.9	2.6	3.2	-1.8	-1.4
Medication: Simvastatin	1.9	2.9	5.6	-2.4	0.4
Fluid intelligence score	1.9	4.0	7.9	-0.2	-2.8
Impedance of arm (right)	1.9	8.8	15.8	1.4	4.0
Arm predicted mass (right)	1.9	9.5	18.1	4.3	-0.9
Medication: Aspirin	1.9	2.5	2.5	-1.6	1.5
Age started oral contraceptive pill	1.9	2.4	4.2	0.8	-2.0
Vascular/heart problems diagnosed by doctor	1.9	5.3	6.6	2.6	-2.0
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	3.7	0.4	1.9
Impedance of arm (left)	1.8	8.3	15.7	0.9	4.0
Smoking status: Current	1.8	2.8	5.3	-0.6	2.3
Major Depression (MDD)	1.7	2.1	3.9	-2.0	0.6
Neuroticism	1.7	4.1	8.1	-2.8	0.3
Systolic blood pressure, automated reading	1.7	4.8	9.5	-3.1	0.4
Medication: Lansoprazole	1.7	1.9	3.9	-2.0	0.1
Arm fat-free mass (right)	1.7	8.7	16.7	4.1	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	2.8	-1.1	-1.7
Mineral and other dietary supplements	1.7	2.3	4.5	0.0	-2.1
Basal metabolic rate	1.7	9.3	18.5	4.3	-0.1
Ulcerative Colitis (UC)	1.6	2.9	4.5	-1.2	-2.1
Arm fat percentage (right)	1.6	6.5	12.9	-3.6	-0.3
Hypothyroidism/myxoedema (self-reported)	1.6	3.1	5.7	-0.7	-2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	3.8	-1.7	-2.0
Financial situation satisfaction	1.6	1.9	3.7	-1.9	-0.4
Intelligence (Savage-Jansen 2018)	1.5	4.7	7.4	1.4	-2.7
Ever used hormone-replacement therapy (HRT)	1.5	1.9	1.9	1.4	-1.4
Supplements: Glucosamine	1.5	2.0	3.9	-0.2	2.0
Chronic bronchitis/emphysema (father)	1.5	1.8	2.0	1.3	1.4
Number of live births	1.5	2.2	3.2	-1.8	-1.1
Depression (self-reported)	1.5	1.8	3.2	-1.8	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	3.6	0.1	-1.9
Family relationship satisfaction	1.5	1.8	2.9	1.7	0.8
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.9	1.9	-1.4	-1.3
Ever taken oral contraceptive pill	1.5	1.6	2.8	0.7	1.7
Worry (Nagel 2018)	1.4	3.0	5.9	-2.4	0.3
Irritable Bowel Disease (IBD)	1.4	3.2	4.3	-1.5	-2.1
Verbal and Numeric Reasoning (VNR)	1.4	3.3	6.5	-0.3	-2.5
Heel T-Score	1.4	10.8	16.4	-4.0	2.3
Hand grip strength (left)	1.4	3.8	6.3	2.5	-1.2
Hayfever, allergic rhinitis or eczema	1.4	3.1	5.7	-0.7	-2.4
Noisy workplace	1.4	1.7	3.4	-1.8	-0.3
Lung cancer (father)	1.4	1.7	2.3	1.5	-1.1
Body fat percentage	1.4	5.3	10.5	-3.2	-0.4
Health satisfaction	1.4	1.8	3.6	-0.2	1.9
Shortness of breath walking on level ground	1.4	1.7	2.0	-1.2	1.4
Medication: Allopurinol	1.4	1.9	2.1	-1.5	-1.3
Mean time to correctly identify matches	1.4	2.7	4.8	2.2	0.9
Medication: Aspirin	1.4	1.9	3.2	-1.8	0.8
Supplements: Vitamin C	1.4	1.6	2.1	1.0	1.5
Leg predicted mass (right)	1.4	7.3	14.5	3.8	0.2
Schizophrenia vs Biploar Disorder	1.3	1.7	2.3	1.5	1.1
Blood White Count	1.3	9.9	19.4	-0.6	-4.4
Lung FEV1/FVC ratio	1.3	6.5	11.2	-1.4	-3.4
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	2.8	-0.8	-1.7
Father’s age at death	1.3	1.7	3.3	1.8	-0.3
Medication: Cholesterol lowering	1.3	2.1	3.0	-1.1	1.7
Headache pain in last month	1.3	2.3	4.4	-2.1	-0.4
Commuting to job workplace: Car/motor vehicle	1.3	1.5	1.6	-1.1	-1.3
Leg fat-free mass (right)	1.3	7.2	14.4	3.8	0.1
Medication: Paracetamol	1.3	2.1	4.1	-2.0	0.2
Neuroticism (Nagel 2018)	1.2	2.8	5.7	-2.4	-0.1
Alzheimer’s Disease (in father)	1.2	1.3	1.6	1.3	-1.0
Leg fat-free mass (left)	1.2	6.6	13.1	3.6	0.3
Average weekly fortified wine intake	1.2	1.4	2.5	1.6	0.6
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	2.7	-1.6	-0.4
Leg predicted mass (left)	1.2	6.6	13.0	3.6	0.4
Had menopause	1.2	1.5	3.1	1.8	-0.0
Exposure to tobacco smoke outside home	1.2	1.6	1.7	-1.3	1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	1.4	1.1	1.2
Heart disease (mother)	1.2	1.4	2.0	1.4	0.9
Knee pain experienced in last month	1.2	1.8	3.5	-1.9	0.4
Mood swings	1.2	2.2	4.4	-2.1	-0.1
Breast cancer (self-reported)	1.2	1.5	2.0	-0.9	-1.4
Type 2 Diabetes (T2D) (2018)	1.1	2.0	3.6	0.7	-1.9
Hearing difficulty/problems with background noise	1.1	1.7	2.9	0.8	1.7
Worrier / anxious feelings	1.1	2.0	2.9	-1.1	1.7
Ever depressed for a whole week	1.1	1.4	2.6	-0.4	1.6
Depressed Affect (Nagel 2018)	1.0	2.1	4.2	-2.0	0.3
Alzheimer’s Disease (including proxy)	1.0	1.5	2.8	1.7	0.3
Medication for hormone replacement therapy	1.0	1.1	2.1	1.4	0.3
Severe depression (siblings)	1.0	1.1	1.6	-0.7	-1.3
Allergy	1.0	2.3	4.2	0.6	2.0
Alcohol intake versus 10 years previously	1.0	1.4	1.6	1.1	1.3
Gout (self-reported)	1.0	1.4	2.7	-1.6	0.4
Comparative body size at age 10	1.0	2.6	5.2	-2.3	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.2	1.4	-1.0	1.2
Age at first live birth	1.0	1.7	2.4	1.0	1.6
Guilty feelings	1.0	1.5	2.8	-1.7	-0.5
Pain type(s) experienced in last month: Hip pain	1.0	1.2	1.5	0.9	1.2
Irritability	1.0	1.6	3.1	-1.8	-0.4
Basal cell carcinoma (self-reported)	1.0	1.2	2.1	-1.4	0.6
Alcohol drinker status: Previous	1.0	1.1	1.9	-1.4	-0.6
Medication: Metformin	0.9	1.3	2.4	0.5	-1.6
Medication: Atenolol	0.9	1.2	1.6	-1.3	0.9
Mouth/teeth dental problems	0.9	1.4	1.9	1.4	1.0
Heart attack	0.9	1.1	1.8	0.7	1.3
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	1.6	0.8	-1.3
Happiness	0.9	1.1	2.0	-1.4	-0.5
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	2.9	1.7	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.3	-1.1	0.8
Hearing aid user	0.9	1.0	1.9	0.1	1.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.4	0.1	1.6
Number of operations (self-reported)	0.9	1.3	2.5	-0.3	1.6
Diastolic blood pressure, automated reading	0.9	2.7	3.5	-1.4	1.9
Schizophrenia (2018)	0.8	1.6	3.0	0.4	1.7
Prostate Cancer	0.8	1.1	1.5	-1.2	-0.8
Trunk fat percentage	0.8	3.3	6.5	-2.5	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	3.5	-1.9	0.1
Qualifications: None of the above	0.8	1.7	3.2	-1.8	0.3
Pulse rate	0.8	1.4	2.5	0.5	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	3.9	2.0	-1.1
Length of working week for main job	0.8	0.9	1.8	1.4	0.1
Hair/balding pattern: Pattern 4	0.8	2.1	2.9	1.1	-1.7
Peak expiratory flow (PEF)	0.8	1.8	3.5	1.9	-0.1
Ever highly irritable/argumentative for 2 days	0.8	1.0	1.5	-0.6	-1.2
Forced vital capacity (FVC), Best measure	0.8	3.0	6.0	2.4	-0.0
Migraine (self-reported)	0.8	1.0	1.3	-1.1	0.9
Age at last live birth	0.8	1.2	2.3	1.5	0.3
Loneliness, isolation	0.8	1.2	2.3	-1.5	-0.1
Ever had bowel cancer screening	0.8	1.0	1.5	0.6	-1.2
Asthma (self-reported)	0.8	1.6	1.7	1.2	-1.3
Medication: Lisinopril	0.8	1.0	1.6	-1.2	0.7
Medication: Atorvastatin	0.8	1.0	1.8	-1.4	-0.4
Impedance of whole body	0.8	4.0	7.1	0.9	2.7
Crohns Disease (2012)	0.7	1.1	1.9	-1.4	-0.6
Primary Biliary Cirrhosis	0.7	1.0	1.7	1.3	-0.5
Average weekly spirits intake	0.7	0.9	1.7	0.0	1.3
Maternal smoking around birth	0.7	1.1	2.0	0.3	1.4
Pain all over the body in last month	0.7	0.7	1.3	0.3	-1.1
Diabetes (self-reported)	0.7	1.1	2.0	-0.4	-1.4
Eye problems/disorders: None of the above	0.7	0.8	1.1	0.6	-1.1
Illnesses of father: Heart disease	0.7	1.0	1.5	-0.7	1.2
Illnesses of father: None of the above (group 1)	0.7	0.9	1.6	0.4	-1.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.6	0.2	1.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.5	0.5	1.2
Breast Cancer	0.6	1.5	2.2	1.5	0.9
Coronary Artery Disease (CAD)	0.6	0.7	1.3	0.4	1.1
Mean Putamen Volume	0.6	0.6	1.2	1.1	-0.3
LDL Cholesterol	0.6	1.0	1.5	-0.6	-1.2
Ulcerative Colitis	0.6	0.9	1.2	-0.7	-1.1
Allergy or Eczema	0.6	1.5	3.1	-0.1	-1.8
Stomach or abdominal pain in last month	0.6	0.7	1.4	-1.2	0.2
Hair/balding pattern: Pattern 2	0.6	0.8	1.2	-0.6	1.1
Forced vital capacity (FVC)	0.6	2.4	4.7	2.2	-0.1
Asthma	0.6	1.1	1.3	0.9	-1.2
Chest pain or discomfort	0.6	0.8	1.6	0.1	-1.3
Diabetes diagnosed by doctor	0.6	1.0	2.1	-0.2	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.2	-0.8	-1.1
Medication: Gliclazide	0.6	0.6	1.1	-1.1	0.4
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.3	-0.2	1.2
Commuting to job workplace: Cycle	0.6	0.8	1.5	-0.0	-1.2
Bipolar Disorder or Schizophrenia	0.5	1.1	2.0	0.5	1.4
Crohns Disease (2017)	0.5	1.0	1.4	-1.2	-0.8
Ovarian Cancer	0.5	0.7	1.3	0.3	1.1
Falls in the last year	0.5	0.7	0.8	0.8	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.2	-1.1	-0.3
Pulse wave reflection index	0.5	0.6	0.8	-0.9	0.7
Birth weight	0.5	1.1	2.2	1.5	0.1
Worry too long after embarrassment	0.5	0.8	1.3	-0.5	-1.1
Medication: Seretide 50 evohaler	0.5	0.6	0.8	0.6	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.0	0.5	1.0
Back pain experienced in last month	0.5	0.7	1.3	0.5	1.1
Leg fat mass (left)	0.5	1.9	2.7	-1.7	-1.0
Reaction Time	0.4	0.8	1.1	1.1	0.6
Neuroticism (2016)	0.4	0.6	0.7	-0.8	0.7
Supplements: Zinc	0.4	0.4	0.8	-0.2	0.9
Diabetes (father)	0.4	0.5	0.6	0.6	-0.8
Pack years adult smoking proportion	0.4	0.6	0.8	-0.6	0.9
Past tobacco smoking	0.4	0.7	1.1	-1.0	-0.5
Financial difficulties in last 2 years	0.4	0.6	0.7	-0.8	0.7
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	1.5	1.2	-1.1
Illnesses of mother	0.4	0.4	0.9	0.2	-0.9
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.9	0.1	-1.0
Medication: Omeprazole	0.4	0.5	0.7	0.5	-0.9
Leg fat mass (right)	0.4	1.7	2.5	-1.6	-0.9
Long-standing illness, disability or infirmity	0.4	0.6	0.9	-0.6	-0.9
Arm fat mass (left)	0.4	1.5	2.8	-1.7	-0.4
Average weekly champagne plus white wine intake	0.4	0.6	0.6	0.8	-0.7
Average weekly beer plus cider intake	0.4	0.6	1.3	-0.2	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.9	-0.1	-1.0
Pack years of smoking	0.4	0.6	0.9	-0.5	1.0
HbA1C	0.3	0.4	0.4	-0.7	-0.5
Hearing difficulty/problems: Yes	0.3	0.4	0.8	0.3	0.9
Medication: Ramipril	0.3	0.4	0.6	-0.3	0.8
Weight	0.3	1.6	3.1	1.8	-0.3
Time employed in main current job	0.3	0.3	0.5	-0.7	0.4
Mouth/teeth dental problems: Dentures	0.3	0.5	0.7	-0.9	0.5
Arm fat mass (right)	0.3	1.3	2.4	-1.6	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.7	-0.8	0.5
Loud music exposure frequency	0.3	0.3	0.4	0.4	0.7
Wheeze or whistling in the chest in last year	0.3	0.6	0.8	0.9	0.6
Neck or shoulder pain in last month	0.3	0.4	0.6	-0.8	0.5
Pulse rate, automated reading	0.3	0.9	1.8	1.3	-0.0
Suffer from ‘nerves’	0.3	0.5	0.8	-0.9	-0.5
Overall health rating	0.3	0.7	0.9	-1.0	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.4	-0.6	0.6
Smoking status: Previous	0.3	0.4	0.6	0.8	-0.5
Osteoporosis (self-reported)	0.3	0.3	0.6	-0.3	-0.8
Supplements: Calcium	0.3	0.4	0.4	0.5	-0.7
Triglycerides	0.2	0.4	0.5	-0.7	0.5
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.5	0.2	-0.7
Relative age of first facial hair	0.2	0.4	0.7	-0.8	0.3
Impedance of leg (right)	0.2	1.0	1.4	0.8	1.2
Townsend deprivation index at recruitment	0.2	0.2	0.4	-0.7	-0.2
Relative age voice broke	0.2	0.2	0.4	0.6	0.3
Number of incorrect matches in round	0.2	0.4	0.6	-0.5	0.8
Nervous feelings	0.2	0.4	0.5	-0.7	-0.5
Hair/balding pattern: Pattern 3	0.2	0.4	0.6	-0.8	0.3
Breastfed as a baby	0.2	0.3	0.4	-0.4	0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.4	-0.6	-0.2
Whole body fat mass	0.2	0.6	1.3	-1.1	-0.1
Had major operations	0.2	0.2	0.2	-0.5	0.4
Risk taking	0.2	0.2	0.3	-0.5	-0.4
Pain experienced in last month	0.2	0.3	0.3	-0.5	-0.6
Age at First Birth	0.1	0.1	0.2	-0.1	0.5
Lupus	0.1	0.2	0.4	0.0	-0.7
Rheumatoid Arthritis	0.1	0.1	0.2	-0.2	0.5
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.3	0.3
Vitamin and mineral supplements	0.1	0.1	0.2	-0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.6	-0.8	-0.2
Multivitamins +/- minerals	0.1	0.2	0.2	0.4	0.4
Impedance of leg (left)	0.1	0.4	0.5	0.6	0.7
Trunk fat mass	0.1	0.3	0.3	-0.6	0.5
Waist circumference	0.1	0.3	0.3	-0.5	-0.6
Had other major operations	0.1	0.1	0.2	0.4	-0.1
Hip circumference	0.1	0.3	0.5	-0.7	-0.3
Pulse wave Arterial Stiffness index	0.1	0.1	0.2	0.2	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	-0.3	-0.3
Pulse wave peak to peak time	0.1	0.1	0.3	0.5	-0.0
Emphysema/chronic bronchitis	0.1	0.1	0.1	-0.4	0.2
Angina (self-reported)	0.1	0.1	0.1	-0.4	0.2
Eye problems/disorders: Cataract	0.1	0.1	0.1	-0.1	0.3
Bipolar Disorder (2018)	0.0	0.1	0.1	0.3	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.1	0.1	-0.1	-0.4
Hair Pigment	0.0	0.4	0.5	-0.5	-0.7
Tanning	0.0	0.0	0.1	-0.0	-0.2
Angina	0.0	0.1	0.1	-0.3	0.1
Serious illness, injury or assault to yourself	0.0	0.0	0.0	-0.2	-0.1
Glaucoma (self-reported)	0.0	0.0	0.0	0.2	0.1
Medication: Ibuprofen	0.0	0.0	0.1	-0.3	0.0
Number of full sisters	0.0	0.0	0.1	-0.3	-0.0
Leg pain on walking	0.0	0.0	0.0	0.2	0.1
Friendships satisfaction	0.0	0.0	0.1	0.1	-0.2
Eye problems/disorders: Glaucoma	0.0	0.0	0.0	0.1	-0.2
Heart disease (siblings)	0.0	0.0	0.0	0.2	-0.1

Hub : Genes

TRAPPC1

Models

Trait associations