[Hub]/) : Traits : Comparative height size at age 10 :

chr19:36,282,543-38,725,416

Best TWAS P=1.72e-13 · Best GWAS P=4e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ZNF585A 0.08 0.10 lasso 3 0.11 2.6e-13 -5.8 5.5 4.7e-08 -0.80 0.96 0.04 FALSE
2 CommonMind Brain Pre-frontal Cortex ZNF585B 0.09 0.06 enet 20 0.09 2.6e-11 -7.4 -5.4 5.9e-08 0.83 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous ZNF585A 0.09 0.02 lasso 3 0.02 3.8e-03 -5.1 -5.9 3.7e-09 0.82 0.05 0.87 FALSE
4 GTEx Adipose Subcutaneous ZNF585B 0.10 0.10 lasso 8 0.12 1.2e-09 6.3 -6.5 1.0e-10 0.90 0.02 0.98 FALSE
5 GTEx Adipose Visceral Omentum ZNF585B 0.06 0.02 enet 8 0.00 2.5e-01 -7.4 -6.9 3.7e-12 0.96 0.02 0.81 FALSE
6 GTEx Artery Aorta ZNF829 0.11 0.04 lasso 2 0.00 2.5e-01 -7.5 7.2 4.3e-13 -0.99 0.02 0.88 FALSE
7 GTEx Artery Tibial AC092295.7 0.11 0.01 enet 25 0.07 3.6e-06 2.2 -5.3 1.0e-07 0.55 0.51 0.35 FALSE
8 GTEx Artery Tibial ZNF585B 0.17 0.14 lasso 15 0.22 5.6e-17 -5.9 -6.2 4.2e-10 0.88 0.03 0.97 FALSE
9 GTEx Brain Cerebellum ZNF793 0.23 0.02 enet 40 0.07 4.8e-03 -7.4 5.8 5.4e-09 -0.77 0.03 0.73 FALSE
10 GTEx Cells EBV-transformed lymphocytes ZNF585B 0.13 0.10 enet 20 0.13 4.3e-05 -7.4 -5.8 7.0e-09 0.76 0.03 0.94 FALSE
11 GTEx Cells Transformed fibroblasts ZNF585B 0.17 0.20 enet 19 0.22 1.2e-16 -7.5 -6.8 8.1e-12 0.93 0.01 0.99 FALSE
12 GTEx Esophagus Mucosa ZNF585B 0.10 0.04 lasso 4 0.05 2.2e-04 -7.5 -6.0 1.6e-09 0.85 0.02 0.98 FALSE
13 GTEx Esophagus Muscularis ZNF585B 0.14 0.06 enet 23 0.12 1.4e-07 -2.7 -5.7 1.0e-08 0.82 0.06 0.94 FALSE
14 GTEx Heart Atrial Appendage ZNF850 0.08 0.03 enet 15 0.06 1.6e-03 -5.4 5.2 2.5e-07 -0.74 0.22 0.32 FALSE
15 GTEx Lung ZNF585B 0.06 0.08 lasso 5 0.07 7.0e-06 6.3 -6.5 6.5e-11 0.91 0.03 0.97 FALSE
16 GTEx Nerve Tibial ZNF585A 0.06 0.07 lasso 9 0.06 6.9e-05 -7.5 -7.3 2.5e-13 0.99 0.04 0.96 FALSE
17 GTEx Pituitary CTD-2630F21.1 0.14 0.02 lasso 7 -0.01 4.6e-01 6.2 -5.9 3.4e-09 0.90 0.03 0.68 FALSE
18 GTEx Spleen ZNF585A 0.23 0.10 lasso 8 0.07 5.9e-03 -7.6 -6.8 7.9e-12 0.95 0.02 0.85 FALSE
19 GTEx Stomach ZNF585B 0.07 0.07 lasso 5 0.05 1.4e-03 -7.4 -7.4 1.7e-13 0.99 0.02 0.95 TRUE
20 GTEx Thyroid ZNF585B 0.04 0.03 lasso 6 0.01 4.0e-02 6.5 -6.2 4.9e-10 0.93 0.05 0.81 FALSE
21 The Cancer Genome Atlas Breast Invasive Carcinoma ZNF568 0.01 0.01 blup 64 0.01 1.3e-03 -4.7 6.2 5.2e-10 -0.87 0.09 0.68 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma ZNF585B 0.03 0.02 enet 4 0.02 5.4e-06 -7.6 -5.6 1.9e-08 0.85 0.00 0.99 FALSE
23 The Cancer Genome Atlas Colon Adenocarcinoma ZNF585A 0.08 0.06 blup 29 0.05 5.0e-04 -5.8 5.5 3.6e-08 -0.53 0.09 0.28 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF585B 0.11 0.04 blup 33 0.06 1.3e-07 -5.8 -6.3 4.0e-10 0.72 0.01 0.96 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF585B 0.13 0.03 enet 9 0.08 1.5e-09 -7.6 -5.5 2.9e-08 0.80 0.00 1.00 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF585B 0.12 0.04 enet 9 0.07 5.6e-08 -7.6 -5.9 3.3e-09 0.84 0.00 1.00 FALSE
27 The Cancer Genome Atlas Testicular Germ Cell Tumors ZNF568 0.11 0.09 blup 63 0.09 4.1e-04 6.2 5.8 5.2e-09 -0.91 0.04 0.87 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma ZNF568 0.20 0.14 lasso 2 0.14 9.3e-14 -5.4 5.4 5.9e-08 -0.72 1.00 0.00 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma ZNF585B 0.07 0.06 enet 11 0.07 3.4e-07 -5.8 -6.1 1.1e-09 0.84 0.00 1.00 FALSE