[Hub]/) : Traits : Comparative height size at age 10 :

chr2:68,850,921-72,622,480

Best TWAS P=1.96e-24 · Best GWAS P=1.59e-25 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ZNF638 0.06 0.01 bslmm 559 0.02 1.8e-03 10.2 7.2 8.9e-13 0.68 0.02 0.95 FALSE
2 GTEx Artery Aorta ZNF638 0.25 0.07 enet 20 0.10 5.2e-06 10.1 10.2 2.0e-24 0.97 0.01 0.99 TRUE
3 GTEx Artery Tibial ZNF638 0.10 0.06 enet 13 0.07 2.4e-06 10.3 9.1 7.8e-20 0.86 0.02 0.98 FALSE
4 GTEx Cells EBV-transformed lymphocytes FAM136A 0.31 0.12 lasso 7 0.16 5.6e-06 4.1 5.5 4.9e-08 0.03 0.06 0.92 TRUE
5 GTEx Cells Transformed fibroblasts NFU1 0.10 0.07 lasso 2 0.03 2.0e-03 7.5 -7.5 4.5e-14 0.06 0.00 0.99 TRUE
6 GTEx Colon Transverse PCYOX1 0.13 0.01 lasso 3 0.00 2.7e-01 -5.3 -5.2 1.9e-07 0.00 0.02 0.90 FALSE
7 GTEx Nerve Tibial GFPT1 0.13 0.01 lasso 4 0.02 1.8e-02 -3.4 5.3 8.8e-08 -0.12 0.18 0.33 FALSE
8 GTEx Skin Sun Exposed Lower leg PAIP2B 0.14 0.07 enet 39 0.07 3.0e-06 7.6 6.0 2.0e-09 0.65 0.24 0.73 FALSE
9 GTEx Small Intestine Terminal Ileum GFPT1 0.24 0.01 enet 19 0.03 8.5e-02 -4.1 5.4 5.2e-08 -0.08 0.08 0.09 FALSE
10 GTEx Thyroid ZNF638 0.11 0.04 enet 13 0.06 1.3e-05 4.2 6.2 5.4e-10 0.64 0.06 0.92 FALSE
11 METSIM Adipose PAIP2B 0.05 0.03 lasso 9 0.03 5.0e-05 7.6 7.2 4.8e-13 0.73 0.71 0.21 FALSE
12 ROSMAP Brain Pre-frontal Cortex GFPT1 0.09 0.01 bslmm 439 0.02 3.2e-04 5.9 5.1 2.9e-07 -0.06 0.10 0.70 FALSE
13 The Cancer Genome Atlas Esophageal Carcinoma ZNF638 0.12 0.08 lasso 1 0.07 2.2e-03 6.9 6.9 4.3e-12 0.74 0.05 0.66 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme CYP26B1 0.19 0.01 lasso 4 0.00 3.6e-01 4.5 6.0 2.5e-09 0.02 0.03 0.11 TRUE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GFPT1 0.05 0.00 blup 67 0.02 5.9e-03 -3.4 5.6 2.4e-08 -0.12 0.03 0.39 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma ZNF638 0.08 0.05 enet 10 0.05 5.6e-06 10.2 9.0 2.7e-19 0.86 0.01 0.99 FALSE