Hub : Genes

PCYOX1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.1180 0.0460 1.9e-03 0.040 NA -0.003 NA 0.025 2.8e-03 NA 5.4e-01 NA 1.6e-02
2 GTEx Artery Tibial 0.2189 0.0504 1.0e-09 0.184 NA 0.164 NA 0.174 2.2e-14 NA 7.2e-13 NA 1.3e-13
3 GTEx Colon Sigmoid 0.1930 0.0790 8.3e-03 0.000 NA 0.000 NA -0.005 3.3e-01 NA 3.1e-01 NA 5.1e-01
4 GTEx Colon Transverse 0.1250 0.0530 7.8e-03 0.012 NA -0.001 NA 0.001 8.3e-02 NA 3.6e-01 NA 2.7e-01
5 GTEx Esophagus Muscularis 0.1810 0.0510 3.4e-06 0.156 NA 0.151 NA 0.131 1.0e-09 NA 1.9e-09 NA 2.5e-08
6 GTEx Skin Not Sun Exposed Suprapubic 0.1440 0.0550 1.8e-03 0.030 NA 0.014 NA 0.022 8.9e-03 NA 5.5e-02 NA 2.2e-02
7 METSIM Adipose 0.0268 0.0125 4.9e-03 0.025 0.018 0.009 0.018 0.015 1.1e-04 8.9e-04 1.2e-02 8.1e-04 1.8e-03
8 YFS Blood 0.0205 0.0077 1.2e-04 0.009 0.014 0.008 0.014 0.008 6.0e-04 1.1e-05 8.5e-04 1.7e-05 7.1e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.1 0.2 1.0 0.1 0.0 0.2 -0.4 -0.1 -0.2 -0.4 -1.0
Bipolar Disorder or Schizophrenia 0.2 0.4 1.5 0.4 0.2 -0.9 -0.0 0.3 0.4 -0.4 -1.2
Depressed Affect (Nagel 2018) 0.1 0.3 1.2 0.4 0.6 0.1 0.4 1.1 0.1 0.1 -0.4
Depression (Nagel 2018) 0.5 0.7 2.1 0.7 0.9 -0.1 0.9 1.4 -0.4 0.1 -1.2
Intelligence (Savage-Jansen 2018) 0.4 1.2 2.4 -0.5 -0.5 1.1 -1.5 -0.3 0.9 1.6 -1.5
Neuroticism (Nagel 2018) 0.1 0.2 1.1 0.1 0.2 0.2 0.4 1.0 -0.1 -0.1 -0.6
Schizophrenia (2018) 0.2 0.4 1.6 0.4 0.3 -1.3 0.3 0.5 0.7 -0.2 -0.8
Schizophrenia vs Biploar Disorder 0.5 0.7 1.8 -0.5 -0.5 -0.9 -1.3 -0.7 -0.3 -1.1 0.6
Worry (Nagel 2018) 0.3 0.7 2.2 -0.8 -0.7 0.3 -0.4 0.0 -1.3 -1.5 -0.3
Alzheimer’s Disease (in mother) 1.8 2.1 3.9 1.6 1.5 0.3 1.1 1.4 2.0 1.4 -1.7
Alzheimer’s Disease (in father) 0.3 0.3 1.0 0.4 0.5 -0.4 1.0 0.8 0.1 -0.8 0.2
Alzheimer’s Disease (including proxy) 0.3 0.4 0.7 0.7 0.6 -0.1 0.8 0.9 0.8 0.3 -0.2
Crohns Disease (2017) 0.1 0.3 1.8 0.1 0.1 -0.2 0.2 0.5 0.2 -1.3 -0.6
Irritable Bowel Disease (IBD) 0.4 1.0 2.9 0.8 0.8 0.1 0.4 1.4 0.9 -0.7 -1.7
Ulcerative Colitis (UC) 0.8 1.5 4.6 1.1 1.1 0.2 0.3 1.6 1.6 0.2 -2.1
Major Depression (MDD) 1.8 2.1 4.0 1.7 1.8 1.3 2.0 1.5 1.2 0.5 -1.1
Reaction Time 1.8 3.4 9.4 -1.2 -1.3 -3.1 -0.1 -0.6 -1.9 -2.7 1.9
Verbal and Numeric Reasoning (VNR) 0.8 2.0 6.1 -1.0 -0.9 1.6 -2.5 -1.4 0.7 1.7 -0.6
Breast Cancer 1.9 4.6 11.5 2.0 1.9 1.3 1.7 2.7 1.7 1.8 -3.4
Ovarian Cancer 0.1 0.1 0.3 -0.0 0.0 0.5 -0.1 0.0 -0.2 0.5 0.6
Prostate Cancer 3.1 4.4 6.8 -2.5 -2.6 -1.8 -2.6 -2.6 -1.8 -0.2 1.5
Age at First Birth 1.6 2.4 7.7 0.6 0.6 2.5 0.6 0.8 1.3 2.8 -1.3
Bipolar Disorder (2011) 0.8 0.8 5.4 0.2 0.2 -0.4 -0.0 0.3 0.7 0.3 -2.3
Body Mass Index (BMI) (2010) 0.4 0.5 1.4 0.3 0.3 0.7 -0.6 0.0 0.8 1.1 -1.2
Coronary Artery Disease (CAD) 0.8 0.9 1.9 -0.7 -0.7 -1.2 -0.7 -1.0 -0.7 -1.0 1.4
Crohns Disease (2012) 0.4 0.6 3.2 -0.3 -0.2 -0.7 -0.5 0.3 0.5 -0.6 -1.8
Mean Putamen Volume 0.3 0.3 0.8 -0.7 -0.6 -0.4 0.1 -0.2 -0.7 -0.9 0.2
Fasting Glucose 0.2 0.2 0.9 -0.1 -0.1 -0.1 -0.1 -0.1 -0.9 -0.7 0.4
HbA1C 0.2 0.3 0.5 0.7 0.6 -0.2 0.5 0.4 0.4 0.6 -0.4
HDL Cholesterol 1.0 1.6 3.2 1.6 1.8 0.8 1.7 1.4 0.5 1.1 -0.4
LDL Cholesterol 1.6 2.5 5.6 1.9 1.8 0.2 2.4 2.2 0.1 0.2 -1.6
Lupus 1.9 2.9 9.1 2.1 2.4 0.1 3.0 1.7 0.9 0.2 -0.7
Neuroticism (2016) 2.0 2.9 4.5 1.7 2.1 0.7 2.0 1.7 1.8 1.0 -2.0
Primary Biliary Cirrhosis 1.1 1.6 4.0 1.6 1.6 0.7 2.0 1.1 0.9 0.2 1.1
Rheumatoid Arthritis 4.4 6.0 10.2 2.7 2.7 1.6 3.2 3.0 2.1 1.2 -2.5
Schizophrenia (2014) 0.2 0.5 2.4 -0.1 -0.3 -1.5 -0.6 0.0 0.6 -0.5 -0.9
Triglycerides 0.2 0.3 1.7 0.3 0.4 -0.1 1.3 0.3 0.2 0.2 0.8
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.5 -0.4 -0.4 -1.0 -0.5 -0.3 -0.5 -1.2 -0.1
Ulcerative Colitis 0.5 0.7 3.8 0.4 0.4 0.0 -0.3 0.9 0.5 -0.1 -1.9
Blood Eosinophil Count 1.0 7.8 17.0 -3.6 -3.6 -2.2 -4.1 -2.8 -1.8 -1.8 0.8
Blood Platelet Count 3.9 44.9 83.2 -7.0 -6.9 -5.2 -6.1 -7.9 -6.0 -4.0 9.1
Blood Red Count 2.4 23.2 30.4 -4.6 -4.6 -5.2 -4.3 -5.5 -4.4 -4.1 5.5
Blood White Count 0.4 2.8 5.6 -2.4 -2.3 1.4 -2.2 -0.7 -1.4 0.2 -1.4
Heel T-Score 0.2 1.3 4.0 -0.0 -0.1 -2.0 0.6 -0.7 -1.2 -0.8 1.8
BMI 0.2 1.2 2.9 0.9 1.0 1.1 1.7 1.1 0.5 1.3 -0.5
Height 1.5 28.3 53.1 -6.4 -6.4 -3.3 -7.3 -6.1 -4.2 -4.9 1.4
Waist Hip Ratio (WHR) 0.3 1.3 1.9 -1.3 -1.4 -0.5 -1.2 -1.4 -0.7 -1.4 0.9
Systolic Blood Pressure 0.2 1.2 3.0 1.5 1.5 -0.1 1.7 0.5 -0.2 0.3 1.4
Smoking Status 0.5 1.2 3.1 0.2 0.2 1.2 -0.8 0.1 1.8 1.7 -1.2
Allergy or Eczema 0.5 1.3 3.6 -1.0 -1.0 -1.0 -0.3 -0.7 -1.7 -1.9 0.3
Cardiovascular Disease 1.2 3.9 12.1 2.5 2.6 0.8 3.5 2.2 0.6 0.2 0.4
Hypothyroidism (self reported) 1.3 2.9 6.7 2.0 1.8 1.4 2.6 2.4 0.7 0.6 -0.7
Respiratory disease 0.5 1.2 2.8 1.1 1.2 -0.3 1.7 1.5 0.8 -0.2 -1.0
Type 2 Diabetes (T2D) (2018) 0.3 0.6 0.8 0.8 0.8 -0.5 0.8 0.9 0.8 0.1 -0.9
Lung FEV1/FVC ratio 0.9 4.5 8.2 2.5 2.5 1.5 2.9 2.5 2.0 1.6 -0.3
Lung FVC 1.3 6.5 20.4 -3.0 -3.1 -0.4 -4.5 -2.9 1.0 1.7 0.9
Neuroticism 0.1 0.2 1.3 0.3 0.5 0.1 0.4 1.1 0.1 -0.2 -0.1
Chronotype (morning person) 0.5 1.2 2.9 -0.5 -0.5 -0.5 1.1 -0.6 -1.7 -1.7 1.4
Hair Pigment 1.2 35.5 56.1 6.5 6.4 5.6 6.5 7.5 5.5 3.5 -5.4
Tanning 0.1 0.7 1.4 -0.6 -0.6 -0.9 -0.8 -0.6 -1.0 -0.6 1.2
Hand grip strength (left) 0.7 1.8 12.5 0.1 -0.0 0.4 -1.2 0.0 0.0 0.4 -3.5
Number of treatments/medications taken 0.1 0.3 1.1 -0.1 -0.1 -0.3 1.0 0.6 0.3 0.1 0.7
Average weekly spirits intake 1.2 1.5 3.1 1.2 1.2 0.6 1.1 1.5 1.8 -0.3 -1.4
Sensitivity / hurt feelings 0.9 1.6 4.5 0.6 0.8 0.9 0.3 2.0 1.4 0.8 -2.1
Frequency of depressed mood in last 2 weeks 0.7 1.0 1.9 1.3 1.4 -0.1 1.3 1.4 0.3 0.8 -0.8
Hearing difficulty/problems: Yes 1.4 2.1 4.6 1.9 1.9 0.2 2.1 1.9 0.4 -0.5 0.8
Relative age of first facial hair 0.6 1.2 3.7 -0.8 -0.7 0.2 -0.2 -0.8 -1.9 -0.9 1.8
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 1.9 -1.2 -1.2 -0.5 -1.4 -0.7 -0.1 -0.5 -0.2
Ever used hormone-replacement therapy (HRT) 0.6 0.8 1.5 0.8 0.7 1.2 -0.2 0.8 1.0 0.9 -1.1
Ever had hysterectomy (womb removed) 2.8 3.2 4.7 -1.6 -1.6 -1.6 -1.6 -1.9 -2.0 -2.2 1.8
Systolic blood pressure, automated reading 0.6 1.7 5.3 1.7 1.7 0.8 2.3 1.1 0.6 0.9 0.3
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.3 -0.3 -0.3 -0.2 -0.3 -0.4 0.2 -0.3 -0.5
Angina 1.5 2.0 7.2 -0.9 -0.9 -2.2 0.2 -1.1 -0.4 -0.7 2.7
Medication for hormone replacement therapy 0.3 0.3 0.7 -0.4 -0.3 -0.8 -0.7 -0.6 0.9 -0.2 0.2
Vitamin and mineral supplements 0.6 0.8 1.9 -0.8 -0.7 0.1 -0.2 -1.4 -1.3 -0.9 0.9
Supplements: Zinc 0.5 0.6 1.4 0.1 0.0 0.6 0.6 0.4 -1.0 -1.2 1.2
Medication: Co-codamol 0.8 0.9 2.5 -0.9 -1.0 -0.7 -0.2 -0.9 -0.6 -1.1 1.6
Medication: Metformin 0.3 0.4 2.6 -0.0 -0.1 -0.1 -0.1 0.2 0.3 -0.3 -1.6
Diabetes (father) 0.1 0.1 0.5 0.0 -0.1 0.1 -0.2 -0.7 -0.3 -0.6 0.1
Diabetes (mother) 2.8 3.6 9.8 1.8 1.7 0.8 1.4 2.2 2.1 1.1 -3.1
Severe depression (siblings) 2.4 2.7 6.0 1.6 1.7 1.3 0.7 1.6 2.1 0.7 -2.5
Pack years adult smoking proportion 0.5 0.7 1.4 1.1 1.2 0.2 0.9 1.2 0.2 0.8 -0.3
Impedance of leg (right) 0.1 0.3 1.0 0.5 0.6 -0.8 0.1 0.5 1.0 -0.3 -0.1
Leg fat-free mass (left) 0.6 3.1 4.8 -2.2 -2.2 -0.4 -2.1 -1.8 -2.2 -1.8 -0.2
Trunk fat percentage 1.3 5.3 8.4 2.5 2.5 2.0 2.9 2.9 1.9 1.5 -1.7
Hand grip strength (right) 0.7 1.9 13.6 0.6 0.5 0.7 -0.2 0.5 0.5 0.4 -3.7
Townsend deprivation index at recruitment 0.2 0.3 0.8 0.2 0.2 -0.9 0.6 0.7 0.1 -0.6 0.7
Current tobacco smoking 2.4 3.9 6.1 1.9 2.0 2.2 1.5 1.8 2.5 2.4 -1.3
Average weekly fortified wine intake 2.0 2.3 4.1 -1.6 -1.4 -0.8 -1.8 -2.0 -1.1 -1.8 1.1
Maternal smoking around birth 0.2 0.3 1.1 -0.5 -0.5 -1.0 -0.2 -0.1 0.4 -0.6 -0.2
Fed-up feelings 1.4 2.6 3.8 1.7 1.8 1.4 1.3 1.9 1.6 1.4 -1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.2 0.1 0.3 -0.2 -0.2 0.5 -0.5 -0.4 -0.2
Relative age voice broke 0.3 0.5 1.8 -0.5 -0.4 0.7 0.1 -0.6 -1.3 -0.9 0.6
Taking other prescription medications 0.2 0.2 0.7 -0.1 -0.1 0.1 0.6 0.2 -0.7 -0.6 0.8
Age when periods started (menarche) 0.1 0.2 0.7 -0.1 -0.2 0.2 0.6 0.2 0.5 -0.1 0.8
Bilateral oophorectomy (both ovaries removed) 1.5 1.7 3.0 -1.6 -1.6 -1.0 -0.7 -1.4 -0.9 -1.7 1.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.2 0.4 0.4 -0.1 0.6 0.1 -0.0 0.5 1.1
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.8 0.2 0.3 -0.1 0.9 0.5 -0.7 -0.2 0.7
Qualifications: CSEs or equivalent 2.3 3.1 4.5 2.1 2.1 1.6 1.2 1.5 2.1 1.7 -1.5
Serious illness, injury or assault to yourself 0.3 0.3 0.7 -0.7 -0.7 -0.6 -0.3 -0.8 -0.0 -0.5 0.5
High blood pressure 0.8 2.1 5.2 1.9 1.9 0.8 2.3 2.0 0.3 0.1 -0.4
Hayfever, allergic rhinitis or eczema 1.2 2.7 5.3 -1.9 -1.8 -0.5 -1.2 -1.6 -2.2 -2.3 0.8
Multivitamins +/- minerals 0.0 0.0 0.2 0.2 0.1 -0.2 -0.2 0.4 0.1 -0.1 -0.1
Stomach or abdominal pain in last month 0.9 1.1 3.6 0.7 0.8 -0.8 1.4 0.6 0.2 -0.9 1.9
Supplements: Glucosamine 0.0 0.0 0.1 -0.1 -0.1 0.2 -0.1 0.1 -0.1 0.1 -0.1
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.6 0.2 0.2 0.0 0.5 0.0 -0.2 -0.8 0.0
Medication: Atenolol 2.3 2.8 4.8 1.9 1.9 0.6 1.6 2.2 1.4 1.8 -1.6
Medication: Levothyroxine sodium 1.1 1.9 3.3 1.2 1.1 0.9 1.2 1.8 1.1 1.6 -1.7
Sitting height 1.7 12.0 24.8 -4.3 -4.3 -2.3 -5.0 -4.3 -2.2 -2.0 1.2
Chronic bronchitis/emphysema (father) 0.2 0.2 0.8 0.1 0.1 -0.9 -0.6 -0.2 0.6 -0.0 -0.3
High blood pressure (mother) 0.6 0.9 2.3 0.8 0.8 0.0 1.5 0.8 -0.5 0.4 1.5
Body mass index (BMI) 1.0 4.2 10.2 2.5 2.5 1.5 3.2 2.3 1.2 1.4 -1.0
Impedance of leg (left) 0.1 0.4 1.4 0.8 0.8 -0.6 0.4 0.6 1.2 -0.0 -0.3
Leg predicted mass (left) 0.6 3.4 5.2 -2.3 -2.2 -0.4 -2.2 -1.8 -2.3 -1.8 -0.1
Trunk fat mass 0.5 2.0 3.0 1.4 1.3 1.6 1.6 1.7 0.9 0.7 -1.6
Waist circumference 0.2 0.7 1.9 0.6 0.6 1.4 1.0 0.8 0.1 0.4 -0.8
Number of incorrect matches in round 1.5 2.4 3.3 -1.6 -1.6 -1.6 -1.4 -1.6 -1.8 -1.2 1.7
Past tobacco smoking 0.6 1.0 3.1 -0.4 -0.3 -0.9 0.4 -0.1 -1.4 -1.8 1.4
Alcohol usually taken with meals 2.8 4.5 7.6 -2.7 -2.8 -1.8 -2.1 -2.0 -2.3 -2.0 0.4
Nervous feelings 0.1 0.2 0.8 -0.3 -0.3 -0.6 0.0 0.1 -0.9 -0.6 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 1.0 0.2 0.4 -1.0 -0.0 -0.1 0.2 0.2 0.4
Hearing difficulty/problems with background noise 0.5 0.7 2.8 -0.5 -0.5 -1.7 0.3 -0.3 -0.1 -0.8 1.4
Hair/balding pattern: Pattern 2 3.3 4.2 6.5 -2.6 -2.6 -1.4 -2.1 -2.2 -2.1 -2.0 1.2
Had menopause 2.2 2.7 5.1 1.9 1.9 1.4 2.3 2.2 1.2 0.6 -0.9
Had other major operations 0.2 0.2 0.7 0.1 0.1 -0.2 0.8 0.4 -0.6 0.1 0.7
Forced vital capacity (FVC) 2.4 9.1 31.4 -3.6 -3.6 -1.0 -5.6 -3.7 -0.5 -0.2 0.5
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.3 0.7 0.7 0.6 -0.1 0.6 0.5 -0.0 0.3 0.8
Ever unenthusiastic/disinterested for a whole week 1.2 1.5 3.6 1.4 1.4 0.4 0.6 1.6 1.0 0.4 -1.9
Qualifications: None of the above 2.2 4.7 8.1 2.7 2.8 -0.2 2.9 2.8 2.1 0.9 -1.1
Financial difficulties in last 2 years 0.8 1.1 2.7 1.3 1.4 -0.7 1.6 1.2 0.5 -0.0 -0.6
Mouth/teeth dental problems 0.3 0.4 1.0 -0.2 -0.1 0.5 -0.6 -0.2 1.0 0.7 -1.0
Heart attack 0.5 0.7 2.7 0.1 0.0 -0.4 0.4 0.0 1.7 0.8 1.3
Allergy 0.9 2.2 4.2 1.7 1.6 1.1 0.8 1.4 1.5 2.0 -1.2
Pain all over the body in last month 0.9 1.0 2.4 0.7 0.6 -1.1 0.1 0.3 1.4 1.1 -1.6
Diabetes (self-reported) 1.0 1.5 3.9 1.3 1.2 0.0 1.2 1.4 1.2 0.8 -2.0
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 1.4 0.6 0.6 1.2 0.6 0.5 1.0 -0.2 -0.8
Medication: Ramipril 0.3 0.4 1.1 -0.6 -0.7 -0.1 -0.6 -0.7 -0.6 0.2 1.0
Medication: Simvastatin 0.7 1.0 2.9 1.1 1.1 -0.1 1.3 0.6 1.7 0.8 -0.3
Fluid intelligence score 0.6 1.2 4.9 -0.8 -0.8 1.0 -2.2 -0.9 0.3 1.1 -0.3
Illnesses of siblings 0.1 0.2 0.5 0.3 0.2 0.5 0.2 0.5 -0.7 0.3 0.5
Neuroticism score 0.5 1.1 2.8 1.2 1.4 0.4 1.0 1.7 0.8 0.1 -0.8
Weight 0.1 0.2 0.7 -0.3 -0.3 0.5 -0.3 -0.2 -0.6 -0.5 -0.9
Impedance of arm (right) 0.0 0.2 0.6 -0.1 -0.1 -0.0 -0.8 0.2 0.8 -0.3 -0.0
Arm fat percentage (right) 1.6 6.2 9.2 2.8 2.8 2.0 3.0 3.0 2.2 1.9 -1.7
Trunk fat-free mass 1.6 8.9 15.2 -3.6 -3.6 -1.4 -3.9 -3.4 -3.1 -2.7 0.4
Hip circumference 0.3 1.4 2.9 1.2 1.2 1.7 1.2 1.3 0.3 0.9 -1.0
Time employed in main current job 0.2 0.3 1.0 0.4 0.4 0.1 0.7 0.5 -0.1 0.3 -1.0
Alcohol intake versus 10 years previously 1.5 2.3 6.2 1.9 1.9 -0.1 1.9 2.5 0.7 -0.0 -0.9
Father’s age at death 0.2 0.3 1.5 -0.2 -0.1 0.4 -0.2 -0.4 -1.2 -0.4 -0.3
Worrier / anxious feelings 0.1 0.2 0.5 0.1 0.2 0.6 -0.0 0.6 -0.5 -0.6 -0.7
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 2.2 -0.0 0.2 -1.5 -0.5 0.4 0.1 -0.2 0.1
Falls in the last year 0.1 0.2 0.9 -0.3 -0.3 -0.0 0.0 0.2 -1.0 -0.6 -0.0
Hair/balding pattern: Pattern 3 4.3 6.3 9.1 3.0 3.0 1.6 2.1 2.6 2.9 2.9 -1.6
Number of live births 0.2 0.3 1.1 0.1 0.0 -1.1 -0.2 0.3 0.6 0.3 -0.9
Forced expiratory volume in 1-second (FEV1) 1.4 4.7 16.4 -2.5 -2.5 -1.2 -4.0 -2.6 -0.2 -0.1 0.5
Pulse rate 0.4 0.7 2.6 0.4 0.5 0.1 1.0 0.9 0.8 1.6 -0.5
Happiness 0.4 0.5 1.3 0.6 0.6 -0.4 -0.3 0.9 0.9 -0.2 -1.1
Noisy workplace 1.5 1.9 4.8 -1.4 -1.4 -2.2 -1.1 -1.5 -0.6 -1.6 0.6
Qualifications: A levels/AS levels or equivalent 0.9 2.1 6.5 -1.7 -1.6 0.8 -2.6 -1.5 -0.5 1.3 0.1
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.4 -0.6 -0.5 -0.4 -0.6 -0.6 -0.3 -0.0 -0.5
Mouth/teeth dental problems: Dentures 0.1 0.2 0.9 0.0 -0.0 -0.1 0.3 0.2 -0.9 -0.6 0.7
Asthma 0.3 0.7 2.5 0.7 0.9 -0.2 1.6 0.9 -0.5 -0.7 -0.2
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 0.8 -0.7 -0.7 0.9 -0.5 -0.3 0.1 0.6 0.9
Medication: Cholesterol lowering 0.9 1.5 3.5 0.9 0.9 0.1 1.6 1.2 1.9 1.5 -0.4
Depression (self-reported) 2.6 3.2 7.1 2.1 2.3 1.1 2.7 1.9 1.2 1.4 0.6
Medication: Lansoprazole 1.4 1.6 4.1 1.5 1.6 -1.0 2.0 1.5 0.9 0.2 0.0
Prospective memory result 0.3 0.4 1.3 0.6 0.5 0.4 1.2 0.8 -0.1 -0.2 -0.5
Lung cancer (father) 0.3 0.4 1.7 0.5 0.5 0.5 0.3 0.6 0.5 1.3 0.0
Illnesses of mother 0.7 0.9 2.0 -1.0 -1.0 -0.6 -1.4 -1.2 -0.2 -0.3 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.5 4.8 14.4 -2.7 -2.7 -1.6 -3.8 -2.5 -0.4 -0.3 0.6
Pulse wave Arterial Stiffness index 0.1 0.2 0.5 -0.2 -0.2 0.6 0.1 -0.1 0.6 0.7 -0.1
Impedance of arm (left) 0.1 0.3 1.1 0.3 0.3 0.4 -0.6 0.6 1.1 0.4 -0.4
Arm fat mass (right) 0.4 1.6 2.9 1.5 1.5 1.2 1.7 1.6 0.6 0.5 -1.0
Trunk predicted mass 1.6 9.3 15.7 -3.6 -3.6 -1.4 -4.0 -3.5 -3.2 -2.8 0.5
Standing height 2.3 22.9 52.3 -5.8 -5.8 -1.9 -7.2 -5.2 -3.9 -4.1 0.3
Length of working week for main job 0.4 0.4 0.9 0.6 0.6 1.0 0.2 0.5 0.4 0.5 -0.9
Exposure to tobacco smoke at home 0.4 0.4 2.1 -0.2 -0.3 -1.5 -0.3 -0.8 0.3 -0.0 0.6
Breastfed as a baby 1.4 1.8 4.2 -2.0 -2.0 -0.4 -1.1 -1.9 -0.7 -0.7 0.1
Tense / ‘highly strung’ 0.4 0.7 1.2 0.5 0.6 -0.8 1.0 1.1 0.8 -0.7 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 0.8 0.5 0.6 -0.9 0.8 0.7 0.8 0.3 -0.3
Hair/balding pattern: Pattern 4 3.9 9.3 15.7 3.3 3.3 3.5 3.8 4.0 2.1 1.5 -2.0
Birth weight of first child 0.4 0.7 2.1 -0.8 -0.9 -0.3 -1.5 -1.0 0.1 -0.9 0.1
Peak expiratory flow (PEF) 0.2 0.6 1.5 -0.1 -0.1 0.3 -1.1 -0.6 1.1 1.2 0.2
Pulse wave reflection index 0.4 0.5 1.6 0.4 0.3 0.4 0.0 0.1 1.1 1.2 -0.9
Ever highly irritable/argumentative for 2 days 0.7 0.9 3.6 0.1 0.2 -1.4 1.0 0.1 -0.1 -1.9 0.6
Loud music exposure frequency 2.4 2.7 11.2 -1.0 -1.0 -2.4 -0.6 -0.7 -1.0 -3.3 0.6
Qualifications: O levels/GCSEs or equivalent 0.3 0.6 3.3 0.2 0.2 1.8 -0.2 0.1 -0.2 0.8 0.6
Mouth/teeth dental problems: Bleeding gums 2.3 3.0 5.7 2.4 2.3 0.4 1.9 2.0 1.7 1.2 -0.9
Blood clot in the leg (DVT) 1.7 2.2 3.2 -1.6 -1.6 -1.6 -1.8 -1.8 -1.1 -1.1 1.1
Medication: Paracetamol 0.3 0.5 1.6 -0.7 -0.6 -1.3 -0.3 -0.3 -0.0 -0.3 0.9
Headache pain in last month 0.4 0.6 1.7 0.7 0.7 0.3 1.3 1.1 0.9 -0.4 -0.6
Medication for cholesterol, blood pressure or diabetes 1.4 2.4 4.4 -1.3 -1.3 -0.5 -2.1 -2.0 -2.0 -1.2 1.2
Glaucoma (self-reported) 0.2 0.3 0.9 -0.3 -0.4 0.2 -0.5 -0.7 -0.4 -0.1 1.0
Gout (self-reported) 2.1 2.8 5.2 -1.7 -1.7 -0.9 -2.0 -2.0 -2.3 -1.4 1.0
Hypothyroidism/myxoedema (self-reported) 1.4 2.7 5.7 1.8 1.7 0.8 2.3 2.4 0.9 1.2 -1.3
Medication: Amlodipine 0.8 1.1 1.9 1.0 1.1 -1.0 1.4 1.4 1.1 0.7 -0.5
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.5 -0.7 -0.7 -0.4 -0.1 -0.4 -0.5 -0.5 0.4
Birth weight 0.8 1.8 4.0 -1.4 -1.4 -1.3 -2.0 -1.8 -0.8 -0.6 1.0
Chronic bronchitis/emphysema (mother) 0.3 0.4 1.0 0.5 0.6 1.0 0.3 0.2 0.9 0.4 0.7
High blood pressure (siblings) 0.1 0.1 0.5 -0.3 -0.2 -0.1 -0.3 -0.7 0.2 -0.3 -0.0
Forced vital capacity (FVC), Best measure 2.3 8.4 26.5 -3.6 -3.6 -1.4 -5.2 -3.4 -0.7 -0.5 0.6
Body fat percentage 1.7 6.5 10.4 2.9 2.9 1.9 3.2 3.1 2.3 1.7 -2.0
Leg fat percentage (right) 1.7 6.2 11.8 2.9 3.0 1.3 3.4 2.9 2.3 1.5 -1.8
Arm fat-free mass (right) 0.9 4.8 7.2 -2.6 -2.6 -1.2 -2.4 -2.3 -2.7 -2.2 0.2
Exposure to tobacco smoke outside home 0.2 0.3 1.1 0.1 0.1 -1.1 -0.2 -0.1 0.3 -0.9 -0.4
Comparative body size at age 10 0.3 0.9 3.6 0.8 0.8 0.8 -0.1 0.4 -0.1 1.1 -1.9
Number of full brothers 0.2 0.3 1.0 0.6 0.5 0.3 0.5 0.3 -1.0 -0.5 -0.1
Worry too long after embarrassment 1.1 1.8 4.7 1.5 1.6 0.8 1.7 2.2 0.9 0.2 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 0.8 -0.8 -0.7 -0.8 -0.9 -0.5 -0.0 -0.7 -0.0
Wheeze or whistling in the chest in last year 1.2 2.2 4.4 -0.9 -0.9 -1.6 -0.3 -1.4 -2.1 -2.1 1.6
Number of children fathered 0.3 0.3 0.8 0.9 0.8 0.2 0.2 0.2 0.5 0.5 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.0 -0.7 -0.7 -0.6 -0.9 -0.9 -1.1 0.6 1.4
Age at first live birth 0.3 0.5 1.4 -0.6 -0.5 -0.0 -0.9 -0.6 -0.3 0.6 -1.2
Pulse wave peak to peak time 0.3 0.3 0.9 -0.2 -0.2 -0.8 -0.7 -0.3 -1.0 -0.8 0.1
Health satisfaction 0.7 0.9 2.0 -0.2 -0.3 -0.3 -1.4 0.1 1.4 1.0 -1.4
Shortness of breath walking on level ground 1.1 1.3 2.5 0.8 0.8 0.9 0.7 1.1 1.6 1.6 -1.2
Qualifications: College or University degree 1.1 3.4 8.0 -2.5 -2.3 0.8 -2.8 -2.1 -1.2 -0.9 0.3
Eye problems/disorders: None of the above 0.6 0.7 1.4 0.8 0.9 -0.1 0.8 0.8 1.2 0.7 -1.0
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.4 0.4 0.5 0.6 0.7 0.6 -1.2 -0.2 -0.1
Emphysema/chronic bronchitis 0.9 1.0 3.6 0.7 0.7 -0.3 0.7 0.9 1.9 1.5 -0.6
Medication for pain relief, constipation, heartburn 0.5 0.8 4.5 0.7 0.8 0.7 -0.2 0.4 -0.1 -0.1 -2.1
Neck or shoulder pain in last month 1.3 1.9 7.2 -0.2 -0.2 -0.8 0.4 -0.6 -0.9 -2.4 2.7
Medication: Blood pressure 0.3 0.5 1.5 0.4 0.4 -0.0 1.2 1.0 0.9 -0.1 -0.7
Angina (self-reported) 1.4 1.8 5.3 -1.1 -1.1 -2.1 -0.1 -1.3 -0.3 -0.7 2.3
Migraine (self-reported) 2.0 2.5 3.8 1.6 1.6 0.6 2.0 1.9 1.5 1.0 -1.8
Medication: Ibuprofen 0.5 0.7 2.2 -0.6 -0.7 1.5 -0.6 -0.1 0.6 1.2 -0.0
Medication: Allopurinol 3.6 4.8 7.1 -2.6 -2.7 -1.4 -2.5 -2.6 -2.4 -1.6 1.1
Medication: Omeprazole 0.3 0.3 2.4 0.0 0.1 -0.2 0.3 0.0 0.2 0.1 1.6
Medication: Seretide 50 evohaler 0.4 0.4 1.6 -0.3 -0.3 0.4 -0.5 -0.7 -1.3 -0.1 0.8
Mean time to correctly identify matches 0.7 1.4 3.8 -0.5 -0.5 -1.6 0.3 -0.1 -0.9 -1.9 1.8
Heart disease (mother) 0.4 0.5 2.9 -0.2 -0.1 -0.5 0.1 -0.4 -0.5 -0.3 1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.8 3.4 6.5 -1.9 -1.8 -1.7 -0.8 -2.0 -1.6 -1.8 2.5
Whole body fat mass 0.6 2.7 4.1 1.7 1.7 1.7 2.0 2.0 1.1 0.8 -1.6
Leg fat mass (right) 0.7 2.6 5.2 1.8 1.8 1.2 2.3 1.9 1.1 0.6 -1.6
Arm predicted mass (right) 1.0 5.0 7.2 -2.6 -2.7 -1.1 -2.5 -2.4 -2.7 -2.4 0.2
Pulse rate, automated reading 1.2 3.8 5.9 1.5 1.6 2.1 1.9 2.4 2.2 2.0 -1.6
Alcohol intake frequency. 0.9 2.0 6.2 1.5 1.5 0.4 2.5 2.2 0.3 -0.6 -0.5
Comparative height size at age 10 2.4 13.4 27.1 -4.0 -3.9 -3.0 -5.2 -4.2 -3.0 -3.6 0.9
Number of full sisters 2.4 3.0 4.4 1.8 1.9 -0.2 2.1 2.0 1.9 0.9 -2.1
Suffer from ‘nerves’ 0.3 0.5 1.4 -0.1 -0.0 -0.6 0.8 0.4 -1.2 -1.1 0.6
Overall health rating 0.7 1.5 3.1 1.6 1.6 -1.0 1.3 1.8 1.0 -0.1 -0.6
Chest pain or discomfort 0.5 0.7 1.8 -0.0 0.0 -1.3 0.3 -0.7 -1.0 -0.8 1.1
Had major operations 0.9 1.1 2.2 0.5 0.6 1.3 0.6 1.0 1.5 0.9 -1.3
Age at last live birth 0.7 1.0 3.2 0.8 0.9 -0.4 0.3 0.7 0.9 1.4 -1.8
Family relationship satisfaction 0.3 0.4 1.0 -0.7 -0.7 -0.4 -1.0 -0.6 -0.1 -0.6 -0.5
Leg pain on walking 0.1 0.2 0.5 0.5 0.5 -0.4 0.4 0.1 0.7 0.1 -0.3
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 3.3 -0.5 -0.6 -1.8 -0.2 -1.4 -0.7 -1.1 1.7
Commuting to job workplace: Car/motor vehicle 0.6 0.6 2.3 -0.5 -0.4 -1.2 -0.5 -0.6 -0.5 -1.5 -0.0
Illness, injury, bereavement, stress in last 2 years 0.8 0.9 1.7 -1.2 -1.2 0.6 -1.3 -0.9 -0.8 -0.7 0.8
Medication: Aspirin 0.2 0.3 1.0 0.2 0.1 -0.8 0.3 -0.2 0.6 0.1 1.0
Supplements: Vitamin C 0.3 0.4 0.6 0.6 0.6 -0.3 0.7 0.7 0.8 0.7 -0.3
Knee pain experienced in last month 0.9 1.4 5.6 -0.8 -0.7 -2.4 0.2 -0.8 -0.9 -1.3 1.0
Hypertension (Self-reported) 0.7 1.8 4.8 1.7 1.7 0.8 2.2 1.8 0.3 -0.0 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.4 -0.1 -0.1 -1.0 1.2 0.8 -0.2 0.0 0.9
Illnesses of father: Heart disease 1.1 1.5 3.6 -1.0 -1.0 -0.6 -0.4 -1.5 -1.3 -1.4 1.9
Illnesses of siblings: Diabetes 0.7 0.8 2.3 0.9 0.8 -0.6 0.8 0.8 1.5 0.1 -1.1
Smoking status: Previous 0.4 0.6 2.0 -0.5 -0.7 -0.3 -0.9 -0.6 0.5 0.6 -1.4
Forced expiratory volume in 1-second (FEV1), predicted 1.5 3.1 5.3 -2.3 -2.3 -1.3 -2.1 -2.1 -1.6 -1.1 -0.2
Whole body fat-free mass 1.1 6.5 10.6 -3.1 -3.1 -1.0 -3.2 -2.8 -2.8 -2.3 0.1
Leg fat-free mass (right) 0.6 3.3 5.2 -2.2 -2.2 -0.1 -2.2 -1.9 -2.3 -1.6 -0.2
Arm fat percentage (left) 1.8 7.2 10.8 3.0 3.0 2.1 3.3 3.2 2.4 2.1 -1.8
Average weekly red wine intake 0.3 0.4 1.3 -0.1 -0.1 -0.2 1.1 0.3 -0.5 -1.1 0.5
Handedness (chirality/laterality): Left-handed 0.7 0.9 4.3 -0.8 -0.9 0.3 -2.1 -0.8 -0.8 0.2 0.1
Mood swings 1.4 2.5 4.1 1.8 1.9 0.1 1.2 2.0 2.0 1.1 -1.5
Loneliness, isolation 1.0 1.3 2.9 1.5 1.6 -0.0 1.2 1.7 0.7 0.1 -0.9
Long-standing illness, disability or infirmity 0.4 0.6 2.5 0.0 0.0 -0.9 0.7 -0.1 -0.4 -0.7 1.6
Ever had bowel cancer screening 0.4 0.4 2.1 -0.4 -0.4 0.5 -0.2 -0.1 -0.8 -1.5 0.5
Diabetes diagnosed by doctor 0.6 0.9 3.0 1.0 0.9 -0.2 0.7 1.1 0.9 0.0 -1.7
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 2.2 1.4 1.5 0.2 1.2 1.2 1.3 0.4 -0.6
Friendships satisfaction 0.2 0.3 1.4 0.1 0.1 -0.4 -0.5 -0.1 1.2 0.0 -0.7
Qualifications: nursing, teaching 1.9 3.0 5.7 -2.0 -2.0 -1.0 -2.4 -2.3 -1.2 -1.1 0.9
Commuting to job workplace: Walk 0.3 0.3 0.8 -0.5 -0.6 -0.2 -0.9 -0.6 -0.8 0.5 -0.0
Eye problems/disorders: Cataract 0.2 0.2 0.9 0.1 0.1 0.6 0.0 -0.0 0.3 0.6 0.9
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 1.2 -0.8 -0.9 -0.2 -0.6 -0.5 -1.1 -0.7 0.9
Medication for cholesterol 1.6 2.4 4.9 -2.2 -2.2 -0.1 -2.0 -1.7 -1.5 -0.3 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.3 2.7 4.4 -2.1 -2.0 -1.2 -1.4 -1.6 -1.5 -1.9 1.4
Back pain experienced in last month 0.3 0.5 1.3 0.8 0.9 -0.5 0.9 0.3 -0.2 -0.4 1.1
Mineral and other dietary supplements 0.3 0.4 1.1 -0.7 -0.6 -0.8 -0.8 -1.1 -0.1 -0.3 0.4
Breast cancer (self-reported) 0.7 0.8 3.2 -0.9 -0.9 -0.2 -0.8 -0.7 0.1 -0.7 1.8
Asthma (self-reported) 0.4 0.7 2.4 0.8 0.9 0.1 1.6 1.0 -0.5 -0.7 -0.4
Osteoporosis (self-reported) 0.5 0.7 1.4 -1.2 -1.2 -0.1 -0.5 -0.4 -0.7 -1.1 0.6
Osteoarthritis (self-reported) 0.3 0.4 2.3 -0.4 -0.3 -0.3 0.2 -0.6 -0.6 -0.2 1.5
Medication: Aspirin 0.2 0.3 1.0 0.3 0.2 -1.0 0.5 -0.1 0.4 -0.1 1.0
Medication: Gliclazide 0.7 0.8 1.3 1.1 1.1 0.7 1.0 1.1 0.4 -0.8 -0.8
Illnesses of father: None of the above (group 1) 1.7 2.1 4.0 1.4 1.5 1.2 1.9 2.0 1.1 1.2 -0.8
Smoking status: Current 2.7 4.3 7.4 2.1 2.2 2.3 1.4 1.8 2.7 2.4 -1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 1.3 -0.8 -0.9 -1.0 -1.1 -0.9 0.4 0.2 1.1
Whole body water mass 1.2 6.8 10.6 -3.2 -3.2 -1.1 -3.2 -2.9 -2.9 -2.5 0.2
Leg predicted mass (right) 0.6 3.4 5.3 -2.2 -2.3 -0.2 -2.2 -1.9 -2.3 -1.7 -0.2
Arm fat mass (left) 0.5 2.2 3.8 1.7 1.7 1.3 2.0 1.8 0.9 0.8 -1.2
Number of self-reported non-cancer illnesses 0.9 1.5 5.9 1.2 1.2 0.6 2.4 1.7 0.2 -0.0 0.1
Average weekly champagne plus white wine intake 0.7 0.9 1.8 -1.3 -1.4 -0.7 -1.3 -1.1 -0.3 0.1 0.5
Miserableness 0.1 0.2 0.7 0.3 0.4 0.4 0.1 0.8 0.6 0.3 -0.6
Guilty feelings 0.1 0.1 0.7 0.1 0.1 -0.4 -0.2 0.0 -0.3 0.2 -0.8
Wears glasses or contact lenses 0.3 0.4 0.9 -0.4 -0.4 0.9 -0.1 -0.2 1.0 0.8 -0.4
Ever taken oral contraceptive pill 0.3 0.3 1.3 -0.2 -0.2 0.2 -0.4 0.3 0.1 0.8 -1.1
Hearing aid user 0.8 0.9 4.2 -0.1 -0.1 -0.3 0.7 0.2 -0.8 -2.0 1.1
Mother’s age at death 0.5 0.6 2.1 -0.6 -0.6 -1.2 -0.4 -0.5 -1.4 -0.5 0.2
Financial situation satisfaction 1.0 1.2 3.7 -1.1 -1.1 -1.9 -1.6 -0.7 -0.6 -0.4 -0.5
Tinnitus: Yes, now most or all of the time 0.5 0.6 3.6 0.2 0.2 0.3 0.4 0.2 0.4 -0.5 1.9
Commuting to job workplace: Public transport 0.6 0.7 2.1 -0.2 -0.3 1.0 -0.4 0.1 1.3 1.5 -0.8
Eye problems/disorders: Glaucoma 0.1 0.1 0.5 0.1 0.1 -0.2 -0.1 -0.5 -0.6 -0.2 0.7
Medication: Blood pressure 0.7 1.4 2.9 1.7 1.6 0.1 1.7 1.0 -0.4 -0.6 1.1
Pain type(s) experienced in last month: Hip pain 0.6 0.7 2.2 -0.9 -0.9 -1.2 -0.1 -0.7 -0.4 -1.5 0.5
Supplements: Fish oil (including cod liver oil) 0.3 0.4 0.7 0.8 0.7 0.0 0.9 0.8 0.4 0.5 -0.2
High cholesterol (Self-reported) 3.8 6.8 16.2 3.1 3.2 1.4 4.0 2.7 2.5 1.8 -0.1
Medication: Bendroflumethiazide 1.0 1.5 2.9 1.5 1.5 0.2 1.7 1.6 -0.4 -1.0 -0.9
Medication: Paracetamol 0.3 0.4 2.2 -0.7 -0.7 -1.5 -0.3 0.1 0.1 -0.3 0.2
Medication: Lisinopril 0.3 0.4 0.9 -0.8 -0.9 0.1 -0.1 -0.8 0.5 0.6 -0.6
Medication: Atorvastatin 0.5 0.6 1.4 0.6 0.6 -1.0 1.1 1.2 0.3 0.8 0.2
Illnesses of father: High blood pressure 0.1 0.1 0.3 0.4 0.4 -0.0 0.4 0.5 0.1 0.4 0.5
Alcohol drinker status: Never 0.1 0.1 0.4 0.2 0.1 0.5 0.2 0.1 -0.1 0.6 0.4
Ever smoked 0.9 1.6 3.7 0.9 0.9 1.6 0.1 0.8 1.4 1.9 -1.5
Basal metabolic rate 0.8 4.3 6.6 -2.5 -2.5 -0.8 -2.6 -2.3 -2.4 -2.0 -0.0
Leg fat percentage (left) 2.1 7.4 13.5 3.2 3.2 1.5 3.7 3.0 2.6 1.8 -2.0
Arm fat-free mass (left) 0.9 4.7 6.7 -2.5 -2.5 -0.9 -2.5 -2.4 -2.6 -2.2 0.3
Number of operations (self-reported) 0.2 0.3 0.7 -0.8 -0.7 -0.1 -0.4 -0.6 0.3 0.3 0.9
Average weekly beer plus cider intake 0.6 0.9 4.2 -0.0 -0.0 0.8 -1.1 -0.6 0.5 -0.5 -2.0
Irritability 0.2 0.4 0.7 0.8 0.8 0.2 0.6 0.7 0.8 0.2 0.3
Risk taking 0.1 0.1 0.5 0.3 0.3 0.7 -0.2 -0.2 0.4 -0.0 -0.0
Ever had prostate specific antigen (PSA) test 1.6 1.8 3.0 -1.5 -1.5 -0.2 -1.3 -1.4 -1.3 -1.7 1.4
Fractured/broken bones in last 5 years 0.4 0.5 1.3 -1.1 -1.1 -0.7 -0.5 -0.6 -0.3 -0.8 0.2
Age started oral contraceptive pill 3.1 3.9 6.3 -2.5 -2.5 -1.0 -2.2 -2.0 -2.2 -1.7 1.2
Diastolic blood pressure, automated reading 0.4 1.3 4.3 1.3 1.4 0.9 2.1 0.5 0.3 1.0 -0.0
Ever depressed for a whole week 2.0 2.5 4.6 1.8 1.8 1.4 1.6 2.1 1.6 1.1 -0.7
Unable to work because of sickness or disability 1.7 2.1 7.5 -0.8 -0.8 -2.7 -0.2 -0.7 -1.0 -1.6 2.0
Commuting to job workplace: Cycle 2.3 2.8 5.5 -2.1 -2.0 0.1 -2.1 -2.3 -1.8 -0.6 0.5
Myopia 0.5 0.7 1.8 -0.7 -0.7 1.2 -1.3 -0.8 0.3 -0.4 -0.4
Vascular/heart problems diagnosed by doctor 0.4 1.0 3.1 -1.1 -1.1 -0.3 -1.8 -1.3 0.0 0.5 -0.2
Cholesterol lowering medication 1.3 1.9 3.5 1.9 1.9 0.2 1.9 1.4 1.5 0.7 -0.0
Medication: Omeprazole (e.g. Zanprol) 0.3 0.3 2.2 -0.1 -0.2 -0.2 0.2 -0.2 0.2 0.6 1.5
Pain experienced in last month 0.8 1.3 2.0 -1.2 -1.3 1.3 -1.4 -1.2 -1.4 0.4 0.1
Supplements: Calcium 0.6 0.6 1.8 -1.3 -1.3 -0.1 -0.8 -0.4 0.4 -0.7 0.4
Basal cell carcinoma (self-reported) 0.6 0.8 3.2 -0.4 -0.4 -1.4 -0.3 -0.3 -0.8 -1.8 0.1
Heart attack/myocardial infarction (self-reported) 0.6 0.7 3.1 0.2 0.1 -0.3 0.4 0.2 1.8 1.0 1.2
Deep venous thrombosis (DVT) (self-reported) 1.4 1.8 2.9 -1.5 -1.4 -1.4 -1.6 -1.7 -1.1 -1.1 0.9
Heart disease (siblings) 0.6 0.7 3.0 -0.1 -0.0 -1.7 0.2 -0.8 -0.3 -0.7 1.1
Alcohol drinker status: Previous 0.3 0.3 1.3 -0.4 -0.4 0.0 0.8 0.5 -0.1 -1.2 0.4
Pack years of smoking 0.5 0.7 1.6 1.2 1.2 0.2 0.8 1.2 0.4 0.8 -0.4
Impedance of whole body 0.0 0.2 0.9 0.3 0.3 -0.3 -0.3 0.4 0.9 -0.1 -0.1
Leg fat mass (left) 0.7 2.6 5.5 1.8 1.8 1.1 2.3 1.8 1.1 0.7 -1.6
Arm predicted mass (left) 1.0 4.9 7.6 -2.5 -2.5 -1.2 -2.4 -2.5 -2.8 -2.3 0.7