Best TWAS P=1.63e-12 · Best GWAS P=1.84e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | TTC12 | 0.42 | 0.16 | enet | 33 | 0.38 | 7.7e-18 | 5.0 | 5.6 | 2.5e-08 | -0.41 | 0.75 | 0.23 | FALSE |
| 2 | GTEx | Uterus | NCAM1 | 0.41 | -0.01 | lasso | 11 | -0.01 | 5.9e-01 | 4.4 | 5.4 | 7.5e-08 | -0.22 | 0.08 | 0.08 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ANKK1 | 0.04 | 0.02 | blup | 66 | 0.03 | 5.0e-04 | 5.0 | 5.5 | 3.3e-08 | -0.32 | 0.26 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ANKK1 | 0.04 | 0.03 | blup | 67 | 0.04 | 6.3e-05 | 4.7 | -5.5 | 3.4e-08 | 0.39 | 0.64 | 0.04 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | DRD2 | 0.06 | 0.07 | lasso | 2 | 0.07 | 6.6e-09 | -7.0 | 7.1 | 1.6e-12 | -1.00 | 0.00 | 1.00 | TRUE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TTC12 | 0.07 | 0.06 | blup | 48 | 0.04 | 1.6e-02 | 4.3 | 5.1 | 2.9e-07 | -0.25 | 0.02 | 0.61 | FALSE |