Best TWAS P=2.31e-07 · Best GWAS P=5.24e-08 conditioned to 1.74e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | PDXK | 0.14 | 0.11 | lasso | 3 | 0.12 | 6.2e-07 | -5.0 | -5.2 | 2.3e-07 | -0.04 | 0.04 | 0.96 | TRUE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | HSF2BP | 0.16 | -0.01 | blup | 62 | 0.02 | 4.7e-02 | 2.5 | 5.1 | 2.7e-07 | 0.06 | 0.01 | 0.21 | FALSE |