Best TWAS P=4.15e-12 · Best GWAS P=1.18e-08 conditioned to 2.92e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | KREMEN1 | 0.13 | 0.10 | lasso | 5 | 0.11 | 3.3e-12 | -5.1 | -5.4 | 6.3e-08 | 0.15 | 0.05 | 0.95 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CCDC117 | 0.03 | 0.01 | blup | 41 | 0.01 | 2.3e-02 | 4.2 | -5.2 | 1.8e-07 | 0.21 | 0.00 | 0.57 | FALSE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ZNRF3 | 0.44 | -0.01 | blup | 126 | 0.05 | 2.0e-02 | 1.2 | -6.9 | 4.1e-12 | 0.24 | 0.01 | 0.11 | TRUE |