[Hub]/) : Traits : Hypertension (Self-reported) : ← →

chr7:132,241,297-134,834,499

Best TWAS P=1.08e-08 · Best GWAS P=2.78e-09 conditioned to 0.446

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous EXOC4 0.13 0.05 enet 15 0.04 5.8e-04 -3.8 5.1 3.0e-07 -0.13 0.53 0.04 FALSE
2 GTEx Esophagus Mucosa EXOC4 0.22 0.13 enet 25 0.18 2.0e-12 -3.9 5.2 1.8e-07 -0.20 0.98 0.01 TRUE
3 GTEx Heart Atrial Appendage AKR1B1 0.22 0.21 lasso 4 0.19 6.9e-09 -5.6 5.6 2.4e-08 -0.83 0.03 0.97 FALSE
4 GTEx Heart Left Ventricle AKR1B1 0.25 0.08 lasso 7 0.05 8.5e-04 -5.6 5.7 1.1e-08 -0.90 0.02 0.97 TRUE
5 The Cancer Genome Atlas Colon Adenocarcinoma AKR1B15 0.10 0.12 lasso 2 0.12 2.0e-07 -5.6 -5.6 2.0e-08 0.93 0.01 0.99 FALSE
6 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma AKR1B15 0.07 0.08 lasso 2 0.08 2.3e-05 -5.6 -5.6 2.0e-08 0.93 0.02 0.97 FALSE
7 The Cancer Genome Atlas Liver Hepatocellular Carcinoma AKR1B15 0.18 0.12 blup 64 0.14 4.5e-07 -5.6 -5.7 1.6e-08 0.88 0.01 0.99 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma AKR1B15 0.07 0.05 blup 66 0.06 4.5e-07 -5.2 -5.6 1.8e-08 0.91 0.02 0.98 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma AKR1B15 0.31 0.22 lasso 2 0.20 7.7e-09 -5.6 -5.5 3.4e-08 0.93 0.01 0.99 FALSE
10 The Cancer Genome Atlas Rectum Adenocarcinoma AKR1B15 0.37 0.21 lasso 3 0.21 1.2e-05 -5.6 -5.6 1.7e-08 0.94 0.01 0.95 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors AKR1B10 0.11 0.14 lasso 1 0.13 2.4e-05 -5.6 -5.6 2.7e-08 0.91 0.02 0.95 FALSE