TWAS hub - AKR1B15

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0379	0.0176	1.2e-03	0.012	0.011	0.004	NA	0.010	1.3e-03	1.6e-03	4.8e-02	NA	3.1e-03
2	TCGA	Colon Adenocarcinoma	0.1040	0.0440	4.5e-06	0.119	0.098	0.107	NA	0.120	2.2e-07	2.8e-06	9.3e-07	NA	2.0e-07
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.0434	0.0182	3.2e-07	0.071	0.058	0.047	NA	0.058	2.3e-08	4.1e-07	5.3e-06	NA	3.7e-07
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0680	0.0330	8.3e-04	0.079	0.074	0.058	NA	0.081	2.8e-05	4.7e-05	3.2e-04	NA	2.3e-05
5	TCGA	Liver Hepatocellular Carcinoma	0.1840	0.0780	5.8e-06	0.118	0.139	0.131	NA	0.123	3.6e-06	4.5e-07	1.0e-06	NA	2.2e-06
6	TCGA	Lung Adenocarcinoma	0.0320	0.0193	2.3e-03	0.008	0.018	0.009	NA	0.007	3.5e-02	2.8e-03	2.5e-02	NA	5.0e-02
7	TCGA	Lung Squamous Cell Carcinoma	0.0672	0.0303	2.0e-07	0.051	0.057	0.048	NA	0.052	1.9e-06	4.5e-07	3.3e-06	NA	1.5e-06
8	TCGA	Pancreatic Adenocarcinoma	0.3070	0.1210	2.4e-07	0.225	0.174	0.149	NA	0.201	7.9e-10	9.2e-08	8.2e-07	NA	7.7e-09
9	TCGA	Rectum Adenocarcinoma	0.3670	0.1310	1.3e-04	0.212	0.166	0.179	NA	0.210	1.0e-05	1.1e-04	5.4e-05	NA	1.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Hypertension (Self-reported)	8.8	24.3	32.0	2.2	-5.6	-3.3	-5.6	-5.7	-3.8	-5.6	-5.5	-5.6
Medication: Amlodipine	8.0	11.2	14.8	1.5	-3.7	-3.7	-3.7	-3.1	-3.8	-3.0	-3.7	-3.3
High blood pressure	7.5	20.8	28.1	2.3	-5.3	-2.7	-5.3	-5.2	-3.2	-5.1	-5.2	-5.3
Medication: Blood pressure	6.8	12.8	19.4	0.8	-4.4	-2.0	-4.3	-3.8	-2.4	-3.9	-4.3	-4.4
Systolic Blood Pressure	6.6	33.0	46.6	0.9	-6.7	-4.1	-6.7	-6.1	-4.1	-6.8	-6.5	-6.8
Cardiovascular Disease	6.6	21.9	30.1	1.2	-5.3	-3.4	-5.3	-5.5	-3.6	-5.4	-5.2	-5.5
Vascular/heart problems diagnosed by doctor	5.5	14.9	22.5	-1.2	4.7	1.9	4.7	4.3	2.4	4.3	4.6	4.7
Chronic bronchitis/emphysema (mother)	5.4	6.3	10.0	-0.2	2.6	2.5	2.6	2.4	2.5	3.2	2.5	2.9
Medication for cholesterol	5.2	8.0	13.1	-0.3	3.6	0.8	3.6	3.1	1.2	3.0	3.5	3.5
Medication: Bendroflumethiazide	5.0	7.6	11.6	0.3	-3.2	-1.9	-3.2	-3.0	-2.1	-3.2	-3.1	-3.4
Medication: Blood pressure	4.1	7.3	10.3	0.6	-3.2	-1.7	-3.2	-3.0	-2.0	-3.0	-3.2	-3.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.8	8.1	10.9	0.9	-3.0	-3.1	-3.0	-2.6	-2.8	-3.3	-3.0	-3.2
Alcohol drinker status: Never	3.6	4.4	7.1	0.8	2.5	1.4	2.5	2.1	1.2	2.1	2.7	2.5
Average weekly spirits intake	3.1	3.8	5.7	0.3	2.1	2.4	2.1	2.1	2.1	1.7	2.2	2.0
Fractured/broken bones in last 5 years	3.1	4.0	6.7	0.1	2.4	1.4	2.4	2.0	1.0	2.3	2.6	2.4
Medication: Ramipril	2.9	3.7	6.0	-0.1	-2.4	-0.7	-2.4	-1.7	-0.7	-2.3	-2.5	-2.5
Pulse rate, automated reading	2.9	9.3	13.5	1.5	3.4	2.8	3.4	3.7	2.4	2.9	3.5	3.4
Average weekly red wine intake	2.9	4.3	7.0	0.7	-2.4	-1.3	-2.4	-2.6	-1.8	-1.8	-2.3	-2.4
Medication: Aspirin	2.7	3.5	5.3	0.1	-2.1	-1.5	-2.1	-2.3	-1.8	-1.9	-1.9	-2.0
Severe depression (siblings)	2.6	2.9	7.1	-1.2	1.0	2.0	1.0	2.7	2.4	1.9	1.0	1.3
Tinnitus: Yes, now most or all of the time	2.4	2.9	5.0	0.0	2.0	1.2	1.9	1.6	1.5	1.6	2.0	2.2
Pulse rate	2.3	3.9	6.6	1.2	1.8	2.4	1.8	2.6	2.2	1.8	1.8	1.9
Systolic blood pressure, automated reading	2.1	6.2	9.4	1.3	-2.7	-2.0	-2.7	-2.6	-2.2	-3.1	-2.6	-2.7
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	3.1	-0.5	1.8	1.0	1.7	1.7	1.4	1.7	1.6	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	3.6	-1.0	1.6	1.3	1.6	1.9	1.1	1.9	1.7	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	6.2	1.5	-1.3	-1.2	-1.4	-2.5	-1.8	-2.2	-1.2	-1.3
Medication: Aspirin	2.0	2.6	4.0	0.5	-1.8	-1.4	-1.8	-2.0	-1.8	-1.7	-1.6	-1.7
Medication: Omeprazole (e.g. Zanprol)	2.0	2.5	4.3	0.7	1.9	1.0	1.9	2.1	1.1	1.1	1.8	1.9
Diabetes (father)	1.8	2.2	7.0	-1.6	0.5	2.6	0.6	1.0	2.5	1.3	0.6	0.4
Triglycerides	1.7	2.8	4.1	1.9	2.0	0.9	2.0	0.9	-0.2	1.9	2.0	2.0
Osteoarthritis (self-reported)	1.7	2.2	4.0	0.6	1.8	0.2	1.8	1.9	0.9	1.3	1.8	2.0
Primary Biliary Cirrhosis	1.6	2.3	4.2	0.3	1.9	2.1	1.9	1.5	1.8	1.2	0.0	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	7.3	-0.4	-2.3	-2.7	-2.3	-2.0	-2.7	-2.1	-2.3	-2.4
Blood clot in the leg (DVT)	1.6	2.0	4.5	-0.2	-1.2	-2.1	-1.2	-1.6	-1.7	-1.6	-1.0	-1.2
Migraine (self-reported)	1.6	2.0	2.7	0.4	-1.6	-1.5	-1.6	-1.1	-1.6	-1.4	-1.5	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	2.0	3.4	0.8	-1.4	-1.3	-1.4	-1.9	-1.4	-1.6	-1.4	-1.3
Knee pain experienced in last month	1.6	2.5	6.7	-0.9	1.3	0.9	1.3	2.6	1.8	1.6	1.4	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	2.5	-0.5	-1.5	-1.4	-1.5	-1.6	-1.0	-1.4	-1.5	-1.5
Lung FVC	1.5	7.8	10.2	-0.2	-3.1	-2.8	-3.1	-2.9	-2.6	-3.0	-3.0	-3.2
Qualifications: CSEs or equivalent	1.5	2.0	3.9	0.5	1.8	0.9	1.8	0.6	0.4	1.6	1.9	2.0
Mouth/teeth dental problems	1.5	2.4	3.1	0.5	-1.8	-1.6	-1.7	-1.4	-1.7	-1.3	-1.7	-1.6
Impedance of arm (left)	1.5	6.9	9.9	-1.2	2.7	2.6	2.8	3.1	2.7	2.7	2.6	2.6
Medication for cholesterol, blood pressure or diabetes	1.5	2.5	3.9	-0.7	1.9	0.8	2.0	1.6	1.0	1.8	2.0	1.9
Schizophrenia vs Biploar Disorder	1.4	1.9	9.8	-3.1	0.5	0.9	0.6	1.2	1.7	1.0	0.5	0.6
Medication: Paracetamol	1.4	2.3	4.3	-0.8	1.6	1.2	1.7	2.1	1.4	1.5	1.7	1.4
High blood pressure (siblings)	1.4	2.0	4.2	-0.1	-1.6	-0.4	-1.6	-1.4	-0.1	-2.0	-1.7	-2.0
Body fat percentage	1.4	5.6	9.1	0.4	2.4	3.0	2.4	2.2	2.3	2.7	2.4	2.5
Number of children fathered	1.4	1.5	3.6	-1.9	1.1	1.0	1.1	0.9	1.2	1.5	1.1	1.1
Number of full sisters	1.4	1.7	3.8	0.4	1.7	-0.4	1.7	0.9	0.1	1.2	1.8	2.0
Ovarian Cancer	1.3	1.8	2.4	-1.4	1.4	0.7	1.4	1.5	1.0	1.6	1.4	1.5
Smoking Status	1.3	3.0	4.7	-0.1	1.9	1.6	1.9	1.6	1.7	2.0	1.8	2.2
Trunk fat percentage	1.3	5.2	7.1	0.5	2.5	2.7	2.5	2.1	1.9	2.6	2.5	2.5
Age when periods started (menarche)	1.3	3.2	6.3	-0.7	1.8	1.9	1.8	1.9	2.5	1.5	1.8	1.7
Hair/balding pattern: Pattern 2	1.3	1.6	3.0	0.9	1.7	0.2	1.7	1.3	-0.1	1.2	1.5	1.7
Alcohol intake frequency.	1.3	3.0	4.7	0.4	1.8	1.6	1.8	2.2	1.3	2.0	1.9	2.0
Friendships satisfaction	1.3	1.6	3.8	-0.4	-1.3	-1.2	-1.3	-1.4	-0.8	-2.0	-1.1	-1.4
Osteoporosis (self-reported)	1.3	1.6	2.6	-1.6	1.1	1.6	1.1	1.0	1.5	1.2	1.3	0.8
Illnesses of father: None of the above (group 1)	1.3	1.6	3.4	-1.2	-1.3	-1.8	-1.3	-0.7	-1.0	-1.2	-1.4	-1.2
Ever had prostate specific antigen (PSA) test	1.3	1.5	2.3	0.9	-1.2	-1.4	-1.3	-1.0	-1.1	-1.5	-1.2	-1.2
Alzheimer’s Disease (in father)	1.2	1.3	5.1	-2.3	0.1	1.5	0.2	0.9	1.8	0.6	-0.1	-0.1
Verbal and Numeric Reasoning (VNR)	1.2	3.0	6.4	2.4	-0.8	-2.2	-0.8	-2.1	-2.5	-1.8	-0.6	-0.9
Impedance of arm (right)	1.2	5.4	7.9	-0.7	2.4	2.6	2.4	2.8	2.5	2.3	2.4	2.3
Forced expiratory volume in 1-second (FEV1)	1.2	4.0	7.9	0.2	-1.8	-2.4	-1.9	-2.2	-2.8	-1.9	-1.8	-2.0
Breastfed as a baby	1.2	1.4	2.8	1.6	-1.0	-1.1	-1.0	-1.7	-1.6	-0.7	-0.9	-0.8
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	2.3	-0.5	1.5	0.7	1.5	1.2	0.9	1.4	1.5	1.3
Supplements: Vitamin C	1.2	1.5	2.9	-0.1	-1.4	-1.7	-1.4	-0.3	-1.1	-1.2	-1.6	-1.1
Medication: Lisinopril	1.2	1.5	2.5	1.6	-1.5	-0.4	-1.4	-1.0	-0.9	-1.2	-1.4	-1.3
Impedance of whole body	1.2	6.2	8.8	-1.1	2.5	2.6	2.5	3.0	2.8	2.5	2.4	2.4
Crohns Disease (2017)	1.1	2.4	4.2	-0.4	1.7	1.3	1.8	2.0	1.4	1.3	1.8	1.7
Rheumatoid Arthritis	1.1	1.5	4.5	2.1	1.4	0.6	1.4	0.4	0.0	0.8	1.4	1.6
Medication for hormone replacement therapy	1.1	1.2	5.5	0.9	-0.3	2.3	-0.2	0.5	1.9	0.5	-0.5	0.1
Waist circumference	1.1	4.2	6.1	1.1	2.4	2.1	2.4	1.7	1.3	2.0	2.5	2.4
Peak expiratory flow (PEF)	1.1	2.7	4.0	0.2	-1.6	-1.8	-1.7	-1.7	-2.0	-1.6	-1.6	-1.7
Wheeze or whistling in the chest in last year	1.1	1.9	3.4	1.7	1.7	0.8	1.7	0.4	0.0	1.2	1.9	1.6
Risk taking	1.1	1.6	2.4	0.5	1.2	1.5	1.2	1.3	1.2	1.5	1.2	1.3
Diastolic blood pressure, automated reading	1.1	3.4	5.0	1.1	-1.9	-1.6	-1.9	-1.9	-2.0	-2.2	-1.8	-2.0
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	4.0	0.1	-0.7	-2.0	-0.8	-1.4	-1.6	-1.4	-0.6	-0.8
Irritable Bowel Disease (IBD)	1.0	2.4	5.5	-1.3	1.2	1.6	1.3	2.3	1.7	1.6	1.2	1.2
Neuroticism (2016)	1.0	1.5	2.1	-1.2	1.4	0.1	1.4	1.4	0.7	1.4	1.4	1.3
Current tobacco smoking	1.0	1.7	3.0	1.1	1.1	1.5	1.1	1.3	1.3	1.7	1.0	1.6
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	3.8	1.9	-0.8	-1.2	-0.8	-0.9	-1.2	-0.7	-0.8	-0.4
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.0	-0.1	-1.0	-1.3	-1.0	-1.4	-1.3	-1.2	-1.1	-1.2
Noisy workplace	1.0	1.2	2.3	-0.8	1.0	1.0	1.1	1.4	0.9	1.5	0.9	1.0
Forced vital capacity (FVC), Best measure	1.0	3.6	4.8	-0.3	-2.0	-2.2	-2.0	-1.7	-2.2	-1.9	-2.0	-2.2
Leg fat percentage (right)	1.0	3.7	7.6	0.1	1.7	2.8	1.7	1.8	2.4	2.1	1.7	1.8
Medication: Allopurinol	1.0	1.3	2.1	-0.4	-1.5	-0.8	-1.5	-1.3	-0.8	-0.9	-1.3	-1.3
Medication: Omeprazole	1.0	1.2	1.8	1.1	1.3	0.7	1.2	1.3	0.6	0.5	1.2	1.2
Illnesses of father: Heart disease	1.0	1.4	4.7	2.2	1.2	0.2	1.2	0.4	-0.7	0.9	1.4	1.4
Ever had bowel cancer screening	1.0	1.1	2.8	-0.6	0.9	1.7	0.9	0.9	1.5	1.0	0.9	0.9
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.1	-0.3	1.4	0.3	1.3	0.9	0.5	1.0	1.5	1.2
Hearing aid user	1.0	1.2	4.5	-1.2	-0.5	2.1	-0.4	-0.2	2.0	0.2	-0.4	-0.4
Leg fat percentage (left)	1.0	3.7	7.9	-0.0	1.7	2.8	1.7	1.6	2.4	2.2	1.7	1.8
Heart disease (siblings)	1.0	1.2	3.8	0.8	1.0	1.0	1.0	1.9	0.9	0.8	1.0	0.9
Neuroticism	0.9	2.2	4.5	-1.8	1.2	1.9	1.2	1.3	2.1	0.9	1.3	1.0
Hand grip strength (left)	0.9	2.3	6.5	2.0	-0.4	-2.3	-0.5	-1.7	-2.6	-0.8	-0.5	-0.1
High blood pressure (mother)	0.9	1.3	2.2	-0.2	-1.4	-0.6	-1.4	-1.4	-0.6	-1.3	-1.3	-1.5
Impedance of leg (left)	0.9	4.2	5.6	-0.8	2.2	2.0	2.2	2.2	2.4	2.0	2.1	2.1
Forced vital capacity (FVC)	0.9	3.4	6.4	0.5	-1.7	-2.0	-1.7	-2.2	-2.5	-1.8	-1.6	-1.8
Pain all over the body in last month	0.9	1.0	4.6	-2.1	0.5	0.9	0.6	0.7	1.3	0.7	0.6	0.4
Falls in the last year	0.9	1.2	3.4	1.0	-0.9	-0.2	-0.9	-1.9	-0.7	-1.5	-0.8	-1.1
Birth weight of first child	0.9	1.6	2.3	1.2	1.5	1.2	1.5	0.8	0.6	1.3	1.5	1.5
Loud music exposure frequency	0.9	0.9	2.9	-1.7	0.4	1.3	0.5	0.7	1.4	0.7	0.5	0.5
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.1	0.8	-1.0	-1.1	-1.0	-1.8	-1.3	-1.5	-0.9	-1.1
Had major operations	0.9	1.1	3.3	1.8	1.1	0.9	1.1	0.5	0.2	0.7	1.0	1.2
Arm fat percentage (left)	0.9	3.4	5.6	0.6	1.9	2.4	1.9	1.6	1.7	2.2	1.9	2.0
Smoking status: Current	0.9	1.5	2.6	1.3	1.0	1.3	1.0	1.2	1.0	1.6	0.9	1.5
Age started oral contraceptive pill	0.9	1.1	2.1	-0.5	-1.1	-0.6	-1.1	-1.3	-0.5	-1.4	-1.0	-1.4
HDL Cholesterol	0.8	1.4	2.7	-0.7	-1.1	-1.6	-1.1	-1.0	-0.9	-1.3	-1.2	-1.2
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	4.3	2.1	1.1	0.2	1.0	0.8	-0.1	0.1	1.0	1.0
Hand grip strength (right)	0.8	2.1	5.9	1.5	-0.6	-2.1	-0.7	-1.9	-2.4	-1.1	-0.6	-0.5
Medication: Atenolol	0.8	1.0	3.1	0.5	-0.9	0.1	-0.8	-1.8	-0.6	-1.2	-0.8	-1.2
Trunk fat mass	0.8	3.6	5.0	0.8	2.0	2.2	2.0	1.6	1.4	2.2	2.1	2.1
Fluid intelligence score	0.8	1.6	3.3	0.6	-1.0	-1.4	-1.0	-1.7	-1.4	-1.8	-0.8	-1.1
Happiness	0.8	1.0	4.8	-0.3	-0.8	-0.5	-0.7	-2.2	-0.5	-1.2	-0.5	-0.8
Illnesses of mother	0.8	1.0	1.8	0.2	1.3	0.9	1.3	1.2	0.8	0.5	1.4	1.1
Exposure to tobacco smoke outside home	0.8	1.0	3.4	1.8	-0.6	-1.0	-0.6	-0.6	-1.7	-0.7	-0.6	-0.5
Number of full brothers	0.8	1.0	2.5	-0.4	1.0	1.6	1.0	1.0	1.2	0.6	0.9	0.7
Medication: Ibuprofen	0.8	0.9	1.4	1.1	1.2	0.5	1.2	1.0	0.4	0.6	1.1	1.1
Chest pain or discomfort	0.8	1.1	2.2	0.7	1.2	1.5	1.2	0.5	1.2	0.4	1.3	1.0
Guilty feelings	0.8	1.2	3.3	-0.1	1.2	1.8	1.2	0.6	1.0	0.9	1.3	1.0
Ever taken oral contraceptive pill	0.8	0.8	1.9	0.6	1.4	0.6	1.3	0.6	0.2	0.5	1.4	0.9
Financial situation satisfaction	0.8	1.0	1.9	-0.5	0.8	1.2	0.9	0.7	1.1	1.4	1.0	1.1
Medication: Paracetamol	0.8	1.2	2.8	0.1	1.2	0.8	1.2	1.7	0.7	1.1	1.2	1.1
Medication: Atorvastatin	0.8	1.0	1.4	-1.0	-1.1	-1.1	-1.1	-0.4	-0.9	-0.8	-1.1	-1.2
Cholesterol lowering medication	0.8	1.2	2.7	-0.6	-1.1	-0.1	-1.1	-1.5	-0.3	-1.6	-1.0	-1.5
Schizophrenia (2018)	0.7	1.4	3.9	-0.6	1.1	2.0	1.1	0.9	1.7	0.7	1.0	0.8
Coronary Artery Disease (CAD)	0.7	0.8	2.1	-0.5	-1.2	-0.2	-1.1	-1.5	-0.2	-0.8	0.0	-1.1
HbA1C	0.7	0.8	1.8	0.3	1.3	0.5	1.3	0.3	0.0	0.9	1.3	0.9
Impedance of leg (right)	0.7	3.6	5.0	-0.7	2.0	1.8	2.0	2.2	2.1	1.7	2.0	1.9
Average weekly fortified wine intake	0.7	0.8	1.5	-0.5	0.9	0.7	1.0	0.7	0.4	1.2	1.0	1.1
Chronic bronchitis/emphysema (father)	0.7	0.9	1.4	0.0	-1.1	-0.4	-1.0	-1.1	-0.5	-1.2	-1.1	-1.1
Alcohol intake versus 10 years previously	0.7	1.0	2.3	0.4	0.6	1.5	0.6	1.1	1.3	1.2	0.7	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.6	-1.6	-1.1	-0.5	-1.0	0.1	0.4	0.1	-1.2	-0.8
Whole body fat mass	0.7	2.8	4.3	0.8	1.7	2.1	1.7	1.4	1.3	1.9	1.8	1.9
Illnesses of siblings: Diabetes	0.7	0.8	1.8	0.0	0.7	0.8	0.8	1.3	1.1	1.2	0.7	0.9
Number of self-reported non-cancer illnesses	0.7	1.2	2.3	1.5	-1.0	-0.9	-1.0	-1.2	-1.1	-1.2	-0.9	-0.9
Ever smoked	0.7	1.3	2.0	-1.4	1.3	0.0	1.3	0.7	0.6	1.3	1.4	1.4
Pain experienced in last month	0.7	1.1	3.1	-0.1	-0.8	-1.1	-0.8	-1.8	-1.2	-1.0	-1.0	-0.9
Bipolar Disorder or Schizophrenia	0.6	1.4	4.4	0.3	1.0	2.1	1.0	1.0	1.7	1.0	0.9	1.0
Crohns Disease (2012)	0.6	0.9	1.5	0.1	1.2	1.2	1.2	1.0	1.1	0.6	0.0	1.2
LDL Cholesterol	0.6	1.0	3.6	1.9	-0.3	-0.7	-0.4	-1.2	-1.5	-0.9	-0.3	-0.6
Type 2 Diabetes (T2D) (2018)	0.6	1.1	7.1	-2.7	-0.4	0.7	-0.4	-0.5	1.2	-0.2	-0.3	-0.6
Alcohol usually taken with meals	0.6	1.0	2.2	0.2	-1.3	0.2	-1.3	-1.5	-0.1	-0.8	-1.3	-1.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.8	0.4	0.7	1.3	0.8	0.7	1.1	0.5	0.7	0.8
Arm fat percentage (right)	0.6	2.5	4.8	1.0	1.6	2.2	1.6	1.2	1.4	1.7	1.7	1.6
Hip circumference	0.6	2.4	3.5	1.1	1.8	1.7	1.8	1.1	0.8	1.6	1.9	1.8
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	2.6	0.8	1.0	1.6	1.1	0.7	1.1	0.6	1.0	1.0
Pulse wave Arterial Stiffness index	0.6	0.7	5.9	-2.4	-0.0	-0.0	0.0	0.1	0.6	0.2	-0.0	-0.3
Length of working week for main job	0.6	0.6	1.5	-0.6	-0.9	-0.4	-0.9	-1.2	-0.8	-0.4	-0.8	-0.8
Shortness of breath walking on level ground	0.6	0.7	3.7	-1.9	0.2	0.6	0.2	0.6	1.2	0.2	0.2	0.2
Leg fat mass (right)	0.6	2.2	4.0	0.6	1.5	2.0	1.5	1.1	1.4	1.8	1.6	1.6
Family relationship satisfaction	0.6	0.7	2.7	1.6	-0.3	-0.1	-0.3	-1.6	-0.5	-0.8	-0.2	-0.2
Wears glasses or contact lenses	0.6	0.7	1.4	0.7	-1.1	-0.2	-1.1	-0.7	-0.3	-0.7	-1.2	-0.9
Mother’s age at death	0.6	0.8	2.2	1.5	0.2	-1.4	0.2	-0.6	-1.4	-0.2	0.3	0.3
Leg fat mass (left)	0.6	2.2	3.8	0.6	1.5	1.9	1.5	1.0	1.4	1.8	1.6	1.6
Major Depression (MDD)	0.5	0.6	0.9	0.8	-0.8	-0.4	-0.8	-0.9	-1.0	-0.8	-0.7	-1.0
Prostate Cancer	0.5	0.6	1.6	1.3	-0.1	-1.2	-0.2	-0.6	-1.0	-1.1	0.1	-0.1
Bipolar Disorder (2011)	0.5	0.5	1.1	-0.4	-1.1	0.2	-1.0	-0.3	0.3	-0.9	0.0	-1.1
Fasting Glucose	0.5	0.7	1.5	0.5	-1.0	0.1	-1.0	-0.5	-0.3	-0.6	-1.1	-1.2
Lupus	0.5	0.7	2.5	-1.6	1.0	0.2	1.0	0.3	0.3	0.4	1.1	0.6
Supplements: Zinc	0.5	0.6	1.2	1.1	0.6	0.9	0.6	0.8	0.4	0.8	0.5	0.9
Maternal smoking around birth	0.5	0.7	1.9	-0.9	0.6	1.2	0.6	0.8	1.4	0.4	0.7	0.4
Allergy	0.5	1.2	2.7	-0.6	0.7	1.5	0.8	1.2	1.6	1.3	0.7	0.8
Father’s age at death	0.5	0.6	2.2	-1.5	-0.6	1.1	-0.5	-0.1	1.2	0.0	-0.5	-0.3
Worrier / anxious feelings	0.5	1.0	6.1	-2.5	-0.2	0.8	-0.1	0.1	1.3	-0.1	-0.1	-0.3
Number of live births	0.5	0.6	1.2	-0.8	1.0	0.3	1.1	1.1	0.5	0.4	1.0	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	3.3	1.8	0.7	0.3	0.7	0.3	-0.3	0.1	0.8	0.6
Medication: Lansoprazole	0.5	0.6	0.7	-0.7	0.8	0.6	0.8	0.7	0.7	0.8	0.8	0.7
Lung cancer (father)	0.5	0.5	1.3	0.7	0.8	-0.4	0.8	0.5	-0.5	0.8	0.8	1.2
Pulse wave reflection index	0.5	0.7	2.9	-1.7	-0.7	-0.0	-0.6	-0.9	0.2	-0.2	-0.9	-0.8
Ever highly irritable/argumentative for 2 days	0.5	0.5	0.9	-0.5	0.6	1.0	0.7	0.4	0.9	0.9	0.8	0.8
Pulse wave peak to peak time	0.5	0.6	5.1	2.2	-0.0	-0.1	-0.1	-0.2	-0.7	-0.2	-0.0	0.2
Eye problems/disorders: None of the above	0.5	0.5	1.4	-0.7	-0.2	-1.2	-0.2	-0.8	-0.7	-1.1	-0.3	-0.7
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.9	-0.7	0.0	1.4	0.1	0.4	1.2	1.0	-0.0	0.3
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.2	-0.5	0.6	0.5	0.6	0.7	0.7	1.1	0.7	0.8
Commuting to job workplace: Walk	0.5	0.5	1.7	-0.8	0.2	0.6	0.2	1.3	1.2	0.3	0.2	0.2
Eye problems/disorders: Cataract	0.5	0.6	1.8	0.4	0.4	0.9	0.4	0.9	0.6	1.3	0.4	0.8
Average weekly champagne plus white wine intake	0.5	0.6	1.2	-0.8	-0.8	-0.3	-0.8	-1.1	-0.1	-1.0	-0.8	-0.9
Myopia	0.5	0.7	2.8	1.7	0.8	0.2	0.7	0.5	0.2	0.6	0.8	1.1
Alzheimer’s Disease (including proxy)	0.4	0.5	0.8	-0.4	0.9	0.9	0.9	0.5	0.9	0.8	0.7	0.6
Ulcerative Colitis (UC)	0.4	0.7	2.1	-1.3	-0.1	0.9	-0.0	1.4	1.1	0.7	-0.1	-0.1
Ulcerative Colitis	0.4	0.6	2.0	-0.9	-0.4	1.4	-0.3	0.6	1.2	0.6	-0.2	-0.3
Chronotype (morning person)	0.4	0.9	2.2	-1.5	-0.9	1.1	-0.8	-0.6	1.2	-0.2	-0.9	-1.0
Relative age of first facial hair	0.4	0.7	3.1	0.6	0.5	-1.8	0.4	0.1	-1.5	-0.1	0.5	0.4
Ever had hysterectomy (womb removed)	0.4	0.4	3.2	1.8	-0.1	0.4	-0.2	0.5	0.4	0.3	-0.2	0.1
Angina	0.4	0.6	2.6	-0.0	0.5	1.6	0.5	0.5	1.2	0.5	0.4	0.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.5	-0.5	0.3	1.2	0.3	0.3	1.0	0.9	0.5	0.3
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.2	0.8	-0.6	1.1	-0.6	0.5	0.9	-0.1	-0.6	-0.4
Hearing difficulty/problems with background noise	0.4	0.7	1.4	-0.7	-0.9	0.3	-0.9	-1.0	0.2	-1.0	-0.8	-1.2
Financial difficulties in last 2 years	0.4	0.5	1.5	-0.1	0.7	1.2	0.7	0.0	1.0	0.5	0.7	0.7
Heart attack	0.4	0.6	2.2	-0.0	0.3	1.5	0.4	0.4	0.6	1.3	0.3	0.6
Neuroticism score	0.4	0.8	1.6	-1.2	0.8	1.2	0.8	0.6	1.3	0.2	0.9	0.6
Trunk fat-free mass	0.4	2.2	5.0	1.5	-1.1	-1.6	-1.2	-1.9	-2.2	-1.3	-1.0	-1.1
Time employed in main current job	0.4	0.4	1.0	-0.9	-0.7	0.3	-0.7	-1.0	0.5	-0.4	-0.6	-0.7
Arm fat mass (right)	0.4	1.6	2.8	1.1	1.3	1.7	1.3	0.7	0.8	1.4	1.4	1.3
Trunk predicted mass	0.4	2.1	4.5	1.4	-1.1	-1.5	-1.2	-1.8	-2.1	-1.2	-1.0	-1.0
Angina (self-reported)	0.4	0.5	2.5	0.1	0.4	1.6	0.4	0.4	1.0	0.4	0.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	1.4	0.7	1.2	-0.3	1.1	0.7	-0.3	0.5	1.1	1.2
Asthma (self-reported)	0.4	0.9	1.9	0.3	-0.7	-1.1	-0.7	-1.4	-1.1	-0.9	-0.7	-0.9
Number of operations (self-reported)	0.4	0.6	4.1	2.0	0.4	0.6	0.4	-0.0	0.1	-0.3	0.4	0.4
Average weekly beer plus cider intake	0.4	0.5	1.6	1.3	-0.4	-0.7	-0.4	-0.8	-0.8	-0.8	-0.6	-0.4
Unable to work because of sickness or disability	0.4	0.5	2.2	-1.5	-0.5	0.6	-0.5	0.1	1.1	-0.3	-0.4	-0.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.0	-0.2	0.3	1.4	0.4	0.3	0.6	1.3	0.3	0.5
Alcohol drinker status: Previous	0.4	0.5	1.0	0.3	1.0	0.2	1.0	0.3	0.1	0.7	0.9	0.9
Waist Hip Ratio (WHR)	0.3	1.3	2.1	-0.7	1.4	1.2	1.4	0.9	1.1	0.7	1.5	1.1
Sensitivity / hurt feelings	0.3	0.5	1.8	-0.8	0.3	1.1	0.3	0.3	1.4	0.3	0.4	0.3
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.0	1.4	-0.4	-0.3	-0.4	-0.6	-0.5	-0.6	-0.4	-0.1
Medication: Co-codamol	0.3	0.3	0.6	-0.6	0.5	-0.6	0.5	0.6	-0.5	0.8	0.5	0.6
Diabetes (mother)	0.3	0.4	1.1	-0.5	-0.6	0.8	-0.6	0.3	1.0	-0.1	-0.7	-0.4
Townsend deprivation index at recruitment	0.3	0.4	0.7	0.6	0.7	0.7	0.7	0.2	0.3	0.2	0.8	0.8
Relative age voice broke	0.3	0.4	1.2	0.1	-0.6	-1.1	-0.6	-0.2	-1.0	-0.6	-0.6	-0.6
Serious illness, injury or assault to yourself	0.3	0.4	1.9	0.7	0.4	1.4	0.4	0.0	0.5	-0.2	0.4	0.1
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.3	0.3	-0.7	-0.9	-0.7	-0.9	-1.1	-1.0	-0.7	-0.8
Multivitamins +/- minerals	0.3	0.3	0.7	0.4	0.7	0.2	0.7	0.9	0.0	0.4	0.7	0.6
Stomach or abdominal pain in last month	0.3	0.4	2.7	1.6	0.3	0.1	0.2	-0.2	-0.6	0.2	0.1	0.2
Number of incorrect matches in round	0.3	0.6	1.8	0.5	0.1	1.3	0.2	0.5	1.4	0.9	-0.0	0.5
Past tobacco smoking	0.3	0.6	1.2	0.7	-0.9	0.6	-0.9	-0.3	0.1	-0.7	-1.0	-1.1
Nervous feelings	0.3	0.6	1.5	-1.2	0.2	0.6	0.2	1.2	1.1	0.4	0.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.8	-0.3	0.1	1.7	0.2	-0.1	1.1	0.6	0.2	0.3
Had menopause	0.3	0.4	1.1	1.0	-0.5	-0.2	-0.5	-0.5	-0.6	-0.7	-0.5	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	3.2	-1.8	-0.3	-0.1	-0.3	0.8	0.8	0.6	-0.4	-0.0
Diabetes (self-reported)	0.3	0.4	0.7	-0.7	0.6	0.5	0.6	0.7	0.8	0.6	0.7	0.6
Illnesses of siblings	0.3	0.4	1.3	0.1	0.3	-1.0	0.3	-0.4	-1.1	0.3	0.4	0.6
Mouth/teeth dental problems: Dentures	0.3	0.5	0.9	0.3	0.6	1.0	0.6	0.3	0.9	0.6	0.6	0.9
Asthma	0.3	0.7	1.5	0.4	-0.7	-1.0	-0.7	-1.2	-0.9	-0.8	-0.7	-0.7
Depression (self-reported)	0.3	0.3	1.4	1.2	0.2	-0.8	0.1	0.1	-0.6	-0.3	0.2	0.4
Prospective memory result	0.3	0.4	0.9	-0.1	0.9	-0.2	0.8	1.0	0.3	0.5	0.6	0.7
Hair/balding pattern: Pattern 4	0.3	0.7	1.6	-0.6	-0.8	0.3	-0.8	-0.7	0.5	-1.3	-0.9	-0.9
Comparative body size at age 10	0.3	0.8	1.6	-0.7	0.9	1.1	0.9	0.5	1.2	0.5	1.0	0.7
Medication for pain relief, constipation, heartburn	0.3	0.5	1.1	0.8	-0.5	-0.8	-0.6	-1.1	-1.0	-0.3	-0.6	-0.3
Heart disease (mother)	0.3	0.4	1.5	1.2	-0.3	-0.9	-0.3	0.2	-1.0	-0.2	-0.3	-0.1
Age at last live birth	0.3	0.4	1.0	-0.3	1.0	-0.0	1.0	-0.3	-0.1	0.2	0.9	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.8	1.4	0.5	0.4	0.5	0.0	0.1	-0.2	0.6	0.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.4	-0.7	-0.3	-1.2	-0.4	0.6	-0.3	0.2	-0.5	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	3.6	-1.9	0.4	-0.3	0.4	0.5	0.2	-0.2	0.5	0.1
Back pain experienced in last month	0.3	0.5	0.9	0.2	0.7	0.5	0.7	1.0	0.6	0.2	0.9	0.8
Arm fat mass (left)	0.3	1.2	2.4	1.0	1.1	1.5	1.1	0.5	0.7	1.3	1.2	1.2
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.9	-0.1	0.4	0.8	0.4	0.8	1.0	0.0	0.6	0.3
Illnesses of father: High blood pressure	0.3	0.3	2.0	1.4	-0.1	0.9	-0.1	-0.2	0.4	-0.0	-0.2	-0.1
Ever depressed for a whole week	0.3	0.4	0.9	0.9	0.6	0.7	0.6	0.7	0.6	0.3	0.7	0.6
Commuting to job workplace: Cycle	0.3	0.3	1.1	-1.1	0.3	0.6	0.3	0.1	1.0	0.4	0.3	0.2
Supplements: Calcium	0.3	0.3	1.0	1.0	-0.0	-0.6	-0.0	-0.2	-1.0	-0.4	0.2	-0.0
Bipolar Disorder (2018)	0.2	0.4	1.3	1.1	0.2	0.9	0.2	0.4	0.6	0.6	0.2	0.5
Depressed Affect (Nagel 2018)	0.2	0.5	2.0	-0.8	-0.2	1.4	-0.1	-0.0	1.1	-0.1	-0.1	-0.2
Age at First Birth	0.2	0.3	0.7	0.1	0.1	0.8	0.1	0.8	0.7	0.7	-0.1	0.2
Blood Eosinophil Count	0.2	1.7	5.2	-2.3	-1.0	-1.0	-0.9	-2.0	-0.7	-0.9	-0.8	-1.2
Blood Platelet Count	0.2	2.0	4.6	-2.1	0.6	1.8	0.6	1.3	2.1	1.4	0.8	0.4
Allergy or Eczema	0.2	0.4	1.7	-1.3	-0.5	0.4	-0.5	-0.2	0.6	-0.5	-0.5	-0.7
Medication: Metformin	0.2	0.2	0.8	-0.6	0.2	0.9	0.2	-0.1	0.7	0.5	0.3	0.2
Fed-up feelings	0.2	0.4	1.5	-0.8	-0.2	1.2	-0.2	0.0	0.9	-0.0	-0.2	-0.2
Taking other prescription medications	0.2	0.3	2.0	1.4	0.2	0.6	0.2	0.1	0.1	0.1	0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	2.6	-1.6	-0.2	-0.6	-0.2	0.4	0.2	0.3	-0.3	-0.1
Supplements: Glucosamine	0.2	0.3	2.0	1.4	-0.3	0.3	-0.3	-0.6	-0.1	0.1	-0.2	-0.0
Medication: Levothyroxine sodium	0.2	0.3	1.2	-0.4	-0.0	1.1	0.0	0.1	0.7	0.8	-0.1	0.2
Had other major operations	0.2	0.3	0.7	-0.0	-0.4	-0.5	-0.4	-0.8	-0.4	-0.8	-0.4	-0.7
Qualifications: None of the above	0.2	0.5	1.0	-1.0	-0.8	-0.4	-0.8	0.1	0.4	-0.5	-0.8	-0.7
Medication: Simvastatin	0.2	0.3	0.9	-0.4	-0.5	0.5	-0.5	-0.9	0.8	-0.5	-0.4	-0.5
Weight	0.2	0.9	2.1	1.4	1.0	0.7	1.0	0.3	-0.2	1.0	1.1	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.7	0.8	0.5	-0.5	0.5	0.3	-0.5	-0.0	0.5	0.4
Medication: Cholesterol lowering	0.2	0.2	0.6	0.2	-0.8	-0.1	-0.8	-0.1	0.1	-0.2	-0.8	-0.5
Headache pain in last month	0.2	0.3	0.8	0.1	-0.3	-0.8	-0.4	-0.2	-0.9	-0.7	-0.3	-0.7
Glaucoma (self-reported)	0.2	0.2	0.8	0.0	0.2	0.3	0.1	0.9	0.5	0.5	0.3	0.5
Arm fat-free mass (right)	0.2	0.8	2.4	1.2	-0.4	-1.0	-0.4	-1.2	-1.5	-0.4	-0.3	-0.3
Worry too long after embarrassment	0.2	0.3	1.3	-0.1	-0.5	-0.1	-0.5	-0.7	0.0	-1.1	-0.5	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.7	0.8	0.3	0.4	0.4	0.8	0.7	0.5	0.3	0.7
Health satisfaction	0.2	0.3	2.3	-1.5	0.2	0.1	0.2	-0.2	0.4	-0.3	0.4	0.1
Emphysema/chronic bronchitis	0.2	0.2	0.9	0.4	0.0	-1.0	-0.0	-0.2	-0.7	0.3	-0.1	0.3
Smoking status: Previous	0.2	0.3	0.9	-1.0	0.4	-0.9	0.4	-0.3	-0.3	-0.1	0.4	0.4
Whole body fat-free mass	0.2	1.2	3.3	1.4	-0.7	-1.1	-0.8	-1.4	-1.8	-0.8	-0.6	-0.6
Loneliness, isolation	0.2	0.3	0.9	-0.1	-0.6	0.0	-0.6	-0.9	-0.2	-0.7	-0.5	-0.7
Qualifications: nursing, teaching	0.2	0.3	0.4	-0.2	0.7	0.4	0.7	0.4	0.2	0.6	0.6	0.6
Mineral and other dietary supplements	0.2	0.3	0.6	-0.2	0.8	0.1	0.8	0.4	0.2	0.2	0.7	0.5
Whole body water mass	0.2	1.1	3.1	1.3	-0.6	-1.1	-0.7	-1.4	-1.8	-0.7	-0.5	-0.5
Miserableness	0.2	0.4	0.7	-0.3	-0.8	0.1	-0.8	-0.4	-0.0	-0.7	-0.7	-0.8
Irritability	0.2	0.3	0.7	-0.3	0.8	0.3	0.8	0.2	-0.0	0.4	0.8	0.8
Basal cell carcinoma (self-reported)	0.2	0.2	0.6	0.1	0.4	-0.6	0.4	0.6	-0.7	0.3	0.4	0.3
Neuroticism (Nagel 2018)	0.1	0.3	0.6	-0.1	0.6	0.8	0.6	0.5	0.7	0.1	0.7	0.5
Alzheimer’s Disease (in mother)	0.1	0.1	0.5	0.0	-0.2	0.7	-0.1	-0.3	0.4	0.3	-0.2	-0.2
Breast Cancer	0.1	0.1	0.5	-0.3	0.4	0.2	0.4	0.7	0.3	0.1	0.3	0.4
Mean Putamen Volume	0.1	0.1	0.3	0.3	-0.2	0.1	-0.2	0.6	0.5	-0.3	-0.2	-0.1
Schizophrenia (2014)	0.1	0.3	1.5	-0.4	0.2	1.2	0.3	0.1	0.9	0.3	0.3	0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.2	0.4	0.3	0.5	-0.6	0.5	-0.5	-0.6	-0.2	0.0	0.3
Blood Red Count	0.1	1.0	2.3	-0.2	1.2	0.2	1.2	1.5	0.1	1.0	1.0	1.1
Blood White Count	0.1	0.5	2.0	-1.4	-0.4	0.5	-0.4	-0.1	1.2	-0.0	-0.5	-0.5
Heel T-Score	0.1	0.7	2.2	1.2	-0.2	-1.5	-0.2	0.4	-1.3	-0.6	-0.3	-0.0
BMI	0.1	0.4	2.9	1.7	0.3	0.2	0.3	-0.4	-0.5	-0.0	0.4	0.1
Hypothyroidism (self reported)	0.1	0.3	0.8	0.0	0.6	0.4	0.6	0.2	0.2	0.9	0.7	0.7
Respiratory disease	0.1	0.3	0.9	0.3	-0.4	-0.5	-0.4	-1.0	-0.5	-0.7	-0.4	-0.5
Lung FEV1/FVC ratio	0.1	0.6	1.7	1.3	0.4	-1.3	0.4	0.5	-1.2	-0.0	0.4	0.3
Tanning	0.1	1.6	2.6	1.5	1.4	0.8	1.4	0.9	0.1	1.5	1.5	1.6
Number of treatments/medications taken	0.1	0.2	0.5	0.7	-0.5	0.1	-0.5	-0.4	-0.0	-0.4	-0.4	-0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.4	-0.6	-0.4	0.4	-0.4	-0.4	0.2	-0.6	-0.4	-0.4
Hearing difficulty/problems: Yes	0.1	0.2	1.0	1.0	-0.2	0.4	-0.2	-0.5	0.1	-0.3	-0.3	-0.2
Vitamin and mineral supplements	0.1	0.1	0.5	-0.0	-0.3	0.1	-0.3	-0.7	0.1	-0.1	-0.2	-0.2
Leg fat-free mass (left)	0.1	0.5	1.7	1.2	-0.2	-0.6	-0.2	-0.8	-1.3	-0.1	-0.1	-0.1
Sitting height	0.1	0.6	2.7	0.9	-0.3	-1.0	-0.3	-0.8	-1.6	-0.4	-0.1	-0.3
Body mass index (BMI)	0.1	0.5	1.6	1.2	0.6	0.7	0.6	0.0	0.1	0.6	0.7	0.7
Leg predicted mass (left)	0.1	0.5	1.7	1.2	-0.2	-0.6	-0.3	-0.8	-1.3	-0.1	-0.1	-0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.4	-1.2	0.1	0.4	0.1	0.3	0.3	-0.3	0.0	-0.3
Exposure to tobacco smoke at home	0.1	0.1	0.3	-0.5	-0.3	-0.1	-0.3	0.0	0.3	-0.3	-0.5	-0.3
Tense / ‘highly strung’	0.1	0.1	0.4	0.2	-0.1	-0.4	-0.1	-0.2	-0.4	-0.6	-0.1	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.9	-0.2	-0.1	0.1	-0.1	-1.0	-0.4	-0.5	-0.1	-0.2
Gout (self-reported)	0.1	0.1	0.5	-0.7	-0.2	-0.2	-0.2	-0.1	0.0	0.1	-0.2	-0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.6	0.3	0.6	0.4	0.6	0.1	0.1	0.8	0.5	0.7
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.4	-0.1	0.3	0.2	0.3	0.3	-0.0	0.6	0.3	0.3
Birth weight	0.1	0.1	0.7	0.9	-0.2	0.1	-0.2	-0.2	-0.3	-0.1	-0.2	-0.2
Age at first live birth	0.1	0.2	0.7	-0.3	0.4	-0.6	0.4	-0.6	-0.8	0.2	0.2	0.1
Qualifications: College or University degree	0.1	0.5	1.2	0.7	-0.6	-0.4	-0.6	-0.5	-1.1	-0.6	-0.6	-0.7
Neck or shoulder pain in last month	0.1	0.1	0.5	0.7	0.2	0.4	0.1	0.4	0.4	-0.0	0.1	0.2
Medication: Seretide 50 evohaler	0.1	0.1	0.3	-0.5	-0.2	-0.0	-0.1	-0.0	0.4	-0.2	-0.1	-0.1
Mean time to correctly identify matches	0.1	0.3	0.6	-0.1	-0.6	-0.1	-0.6	-0.1	0.3	-0.6	-0.8	-0.7
Arm predicted mass (right)	0.1	0.6	1.8	0.9	-0.5	-0.8	-0.5	-1.2	-1.3	-0.4	-0.3	-0.3
Comparative height size at age 10	0.1	0.3	1.4	1.2	0.3	-0.3	0.2	-0.1	-0.9	0.1	0.5	0.3
Suffer from ‘nerves’	0.1	0.2	0.6	0.1	-0.2	-0.6	-0.3	-0.3	-0.7	-0.8	-0.3	-0.4
Overall health rating	0.1	0.1	0.8	0.1	0.2	0.9	0.2	0.1	0.4	-0.0	0.2	0.2
Leg pain on walking	0.1	0.1	0.4	-0.6	-0.1	-0.4	-0.1	-0.3	-0.6	0.3	-0.0	0.1
Leg fat-free mass (right)	0.1	0.5	1.9	1.1	-0.4	-0.7	-0.4	-1.0	-1.4	-0.2	-0.2	-0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.5	0.3	0.3	0.4	0.0	0.2	0.2	0.4	0.3
Long-standing illness, disability or infirmity	0.1	0.2	0.5	0.7	0.2	0.6	0.2	-0.2	0.2	0.1	0.4	0.4
Diabetes diagnosed by doctor	0.1	0.2	0.6	-0.7	0.2	0.5	0.2	0.1	0.8	0.2	0.3	0.2
Breast cancer (self-reported)	0.1	0.1	0.3	-0.6	-0.0	-0.1	-0.0	-0.4	-0.2	-0.4	0.0	-0.4
Medication: Gliclazide	0.1	0.1	0.8	-0.9	-0.0	0.1	-0.0	0.2	0.3	0.6	-0.0	0.1
Leg predicted mass (right)	0.1	0.5	1.8	1.0	-0.4	-0.6	-0.4	-1.0	-1.3	-0.1	-0.2	-0.2
Commuting to job workplace: Public transport	0.1	0.2	1.0	1.0	0.1	0.4	0.1	-0.2	-0.4	-0.2	0.2	-0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	0.3	0.1	0.6	0.1	0.3	0.3	0.4	0.3	0.3
High cholesterol (Self-reported)	0.1	0.2	0.9	0.4	-0.1	1.0	-0.0	0.0	0.8	0.2	0.0	0.1
Basal metabolic rate	0.1	0.6	2.0	1.4	-0.3	-0.6	-0.3	-1.0	-1.4	-0.3	-0.1	-0.2
Arm fat-free mass (left)	0.1	0.6	1.5	1.2	-0.5	-0.6	-0.5	-1.2	-1.2	-0.5	-0.3	-0.4
Pack years of smoking	0.1	0.2	0.3	0.1	-0.4	0.2	-0.4	-0.4	-0.1	-0.6	-0.5	-0.5
Arm predicted mass (left)	0.1	0.7	1.6	1.1	-0.6	-0.6	-0.6	-1.3	-1.2	-0.6	-0.4	-0.5
Depression (Nagel 2018)	0.0	0.1	0.3	-0.6	0.1	0.4	0.1	-0.1	0.1	-0.2	0.2	0.1
Intelligence (Savage-Jansen 2018)	0.0	0.2	1.1	1.1	0.2	-0.1	0.2	0.1	-0.2	0.1	0.3	0.2
Worry (Nagel 2018)	0.0	0.1	0.3	-0.2	0.3	0.1	0.3	0.5	0.5	-0.3	0.2	0.2
Reaction Time	0.0	0.1	0.1	0.3	-0.2	0.0	-0.2	0.3	0.3	-0.3	-0.4	-0.2
Body Mass Index (BMI) (2010)	0.0	0.0	0.1	-0.2	0.1	0.3	0.1	-0.2	0.2	0.3	0.0	-0.0
Height	0.0	0.4	0.8	-0.6	0.6	0.6	0.6	0.9	0.6	0.4	0.6	0.5
Hair Pigment	0.0	1.2	5.3	2.3	0.5	0.3	0.5	1.7	0.3	1.1	0.4	0.9
Pack years adult smoking proportion	0.0	0.1	0.1	0.1	-0.2	0.3	-0.2	-0.3	0.0	-0.3	-0.3	-0.3
Hair/balding pattern: Pattern 3	0.0	0.0	0.1	-0.1	0.0	-0.3	0.0	0.1	-0.2	0.1	-0.1	0.1
Standing height	0.0	0.4	1.1	0.9	0.6	-0.3	0.6	0.3	-1.0	0.6	0.6	0.7
Mood swings	0.0	0.0	0.1	-0.4	0.0	0.2	0.1	-0.1	0.2	-0.2	-0.0	0.2
Supplements: Fish oil (including cod liver oil)	0.0	0.1	0.2	-0.0	-0.2	-0.5	-0.2	-0.3	-0.4	0.1	-0.1	-0.0

Hub : Genes

AKR1B15

Models

Trait associations