Best TWAS P=2.39e-17 · Best GWAS P=7.34e-166 conditioned to 1.06e-82
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BLZF1 | 0.06 | 0.00 | bslmm | 609 | 0.02 | 2.7e-03 | -6.200 | 5.4 | 7.1e-08 | 0.08 | 0.35 | 0.02 | FALSE |
| 2 | GTEx | Artery Aorta | ATP1B1 | 0.12 | 0.03 | enet | 12 | 0.04 | 2.0e-03 | 7.222 | -6.0 | 1.8e-09 | -0.12 | 0.46 | 0.03 | TRUE |
| 3 | GTEx | Artery Tibial | AL021068.1 | 0.07 | 0.00 | enet | 31 | 0.00 | 1.8e-01 | -0.026 | -5.4 | 5.6e-08 | -0.17 | 0.09 | 0.07 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | C1orf112 | 0.15 | -0.01 | enet | 36 | 0.08 | 3.7e-05 | 1.013 | 6.2 | 5.4e-10 | 0.15 | 0.13 | 0.04 | TRUE |
| 5 | GTEx | Stomach | ATP1B1 | 0.13 | 0.01 | lasso | 5 | 0.04 | 4.3e-03 | 0.198 | -6.8 | 9.7e-12 | -0.23 | 0.22 | 0.06 | TRUE |
| 6 | GTEx | Vagina | NME7 | 0.47 | 0.16 | lasso | 9 | 0.17 | 9.9e-05 | 4.165 | -7.9 | 1.9e-15 | -0.26 | 0.30 | 0.05 | TRUE |
| 7 | The Cancer Genome Atlas | Glioblastoma Multiforme | C1orf114 | 0.26 | 0.04 | lasso | 8 | 0.07 | 4.8e-03 | 15.945 | -7.6 | 2.5e-14 | -0.28 | 0.01 | 0.06 | FALSE |
| 8 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | NME7 | 0.16 | 0.08 | blup | 150 | 0.07 | 1.0e-08 | -0.624 | -5.2 | 1.7e-07 | -0.17 | 1.00 | 0.00 | TRUE |
| 9 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SLC19A2 | 0.06 | 0.00 | enet | 9 | 0.00 | 1.4e-01 | -1.581 | -8.5 | 2.4e-17 | -0.24 | 0.02 | 0.04 | TRUE |