Best TWAS P=4.62e-13 · Best GWAS P=1.2e-14 conditioned to 0.00738
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | TMEM194A | 0.16 | 0.05 | lasso | 6 | 0.09 | 0.0052 | -7.2 | -5.7 | 1.2e-08 | 0.71 | 0.02 | 0.69 | FALSE |
| 2 | GTEx | Esophagus Mucosa | ARHGEF25 | 0.06 | 0.01 | lasso | 6 | 0.01 | 0.0612 | -7.6 | -6.0 | 1.7e-09 | 0.84 | 0.02 | 0.82 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | KIF5A | 0.13 | 0.00 | enet | 9 | 0.03 | 0.0067 | -7.7 | -7.1 | 1.7e-12 | 0.88 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | INHBC | 0.03 | 0.03 | lasso | 3 | 0.02 | 0.0016 | -7.5 | 7.2 | 4.6e-13 | -0.94 | 0.00 | 0.98 | TRUE |