TWAS hub - TMEM194A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1120	0.0540	2.0e-03	-0.002	0.039	0.041	0.050	0.008	8.8e-01	1.4e-05	7.8e-06	9.6e-07	3.1e-02
2	GTEx	Breast Mammary Tissue	0.1230	0.0560	3.0e-03	0.017	NA	0.054	NA	0.041	4.2e-02	NA	9.6e-04	NA	3.5e-03
3	GTEx	Breast Mammary Tissue (Male)	0.1623	0.0858	2.1e-02	0.052	NA	0.053	NA	0.085	2.5e-02	NA	2.3e-02	NA	5.2e-03
4	GTEx	Esophagus Muscularis	0.2130	0.0780	3.8e-04	0.010	NA	0.065	NA	0.026	7.7e-02	NA	8.8e-05	NA	1.0e-02
5	GTEx	Lung	0.2950	0.1127	1.1e-03	0.009	NA	0.015	NA	0.012	5.8e-02	NA	2.2e-02	NA	4.0e-02
6	GTEx	Muscle Skeletal	0.1281	0.0523	1.8e-03	0.012	NA	0.017	NA	0.013	2.3e-02	NA	7.4e-03	NA	1.6e-02
7	GTEx	Skin Sun Exposed Lower leg	0.2860	0.0830	1.6e-06	0.147	NA	0.134	NA	0.154	3.3e-12	NA	3.3e-11	NA	1.0e-12
8	YFS	Blood	0.3264	0.0512	3.7e-11	0.000	0.053	0.046	0.045	0.016	2.8e-01	9.3e-17	8.2e-15	1.4e-14	4.1e-06
9	TCGA	Breast Invasive Carcinoma	0.0491	0.0211	7.6e-04	0.026	0.018	0.027	NA	0.024	3.2e-06	9.7e-05	2.2e-06	NA	7.8e-06
10	TCGA	Thyroid Carcinoma	0.1540	0.0560	2.3e-07	0.067	0.094	0.092	NA	0.090	4.6e-07	1.8e-09	3.0e-09	NA	4.3e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Headache pain in last month	7.8	13.4	43.3	-4.0	-3.0	-3.0	-3.4	-4.5	-0.4	-2.6	-4.2	-0.9	-6.6
Gout (self-reported)	7.5	10.3	32.5	-2.3	-4.9	-5.7	-2.8	-1.8	-1.4	-2.7	-2.9	-1.2	-3.3
Medication: Ibuprofen (e.g. Nurofen)	5.7	7.2	15.5	-2.5	-2.6	-2.9	-2.9	-3.9	-2.4	-1.9	-1.6	0.9	-3.8
Medication for pain relief, constipation, heartburn	5.6	9.5	38.9	1.7	2.8	3.8	0.3	5.2	1.6	0.7	-0.4	-0.0	6.2
Medication: Ibuprofen	5.0	6.0	14.8	-1.7	-2.6	-2.9	-2.0	-3.9	-2.3	-1.8	-1.2	0.7	-3.6
Asthma (self-reported)	4.8	9.6	33.5	3.4	2.0	2.8	1.8	2.5	-0.4	1.7	4.4	2.7	5.8
Respiratory disease	4.5	10.0	41.9	2.3	2.4	3.4	1.6	2.3	0.4	1.7	4.2	2.7	6.5
Asthma	4.5	8.9	32.3	3.5	1.6	2.5	1.8	2.1	-0.5	1.5	4.5	2.4	5.7
Migraine (self-reported)	4.5	5.6	31.6	-2.6	-0.8	-0.2	-1.5	-1.9	-0.0	-1.7	-2.7	-1.1	-5.6
Vitamin and mineral supplements	4.1	5.5	34.2	2.1	1.4	2.4	0.7	1.5	0.6	0.9	0.9	1.9	5.8
Triglycerides	3.6	5.9	16.6	-3.1	-3.1	-4.1	-2.5	-1.9	-0.5	-1.5	-3.2	-0.7	-0.4
Tinnitus: Yes, but not now, but have in the past	3.6	3.8	10.9	-1.2	-3.3	-2.6	-1.0	-1.2	-1.2	-3.2	-2.1	0.1	-0.8
Mineral and other dietary supplements	3.6	4.9	13.6	2.2	1.1	2.7	1.9	0.3	0.4	0.3	3.7	2.3	3.5
Medication: Allopurinol	3.4	4.5	16.2	-1.7	-3.4	-4.0	-1.9	-0.7	-0.2	-1.5	-2.0	-0.6	-1.9
Allergy	3.3	7.7	37.9	-2.7	-0.8	-1.8	-1.5	-1.1	2.8	0.3	-3.4	-2.2	-6.2
Smoking status: Previous	3.2	4.7	14.5	1.1	3.8	3.3	2.6	2.0	0.9	2.5	0.4	-1.2	-1.1
HbA1C	3.0	3.3	9.2	-1.2	-1.9	-2.0	-3.0	-2.2	-2.2	-1.6	-1.6	-0.2	0.2
Pulse wave peak to peak time	3.0	3.5	9.4	-0.8	-3.1	-2.5	-1.0	-2.1	-2.2	-2.8	0.7	0.7	0.1
Tinnitus: Yes, now most or all of the time	3.0	3.4	9.0	2.5	1.2	-0.1	1.0	1.5	3.0	2.5	1.8	0.9	2.1
Supplements: Fish oil (including cod liver oil)	3.0	3.9	12.0	-0.7	-1.3	-2.2	-1.4	-0.7	-0.5	-0.4	-3.1	-2.7	-3.5
Pulse wave Arterial Stiffness index	2.9	3.3	8.4	1.0	2.9	2.2	0.9	1.9	2.2	2.8	-0.9	-1.1	-0.2
Past tobacco smoking	2.8	5.1	14.0	-1.0	-3.7	-3.7	-3.3	-1.7	-1.5	-2.0	-0.2	1.1	1.3
Myopia	2.8	4.1	9.4	-2.2	-2.3	-3.1	-2.5	-2.6	0.1	-1.4	-1.0	-0.4	-2.3
Intelligence (Savage-Jansen 2018)	2.7	8.2	19.7	-1.9	-4.4	-3.8	-3.1	-1.2	-2.2	-3.1	-2.7	-1.7	-2.9
Allergy or Eczema	2.7	7.1	38.6	3.8	1.0	1.2	1.6	1.3	-2.1	-0.1	2.6	0.6	6.2
Medication: Lansoprazole	2.7	3.1	10.6	0.6	2.2	0.7	1.5	-0.0	2.9	3.3	1.9	0.6	0.5
Medication: Paracetamol	2.7	4.1	13.3	-1.2	-2.3	-2.7	-0.7	-3.7	-0.3	-1.2	-0.2	-0.9	-3.3
Multivitamins +/- minerals	2.6	3.2	18.0	-1.4	-1.0	-1.4	-1.0	-1.7	-0.4	-0.2	-1.4	-1.9	-4.2
Mouth/teeth dental problems: Bleeding gums	2.6	3.4	13.9	-1.6	-0.7	0.9	-0.8	-0.2	-3.2	-3.7	0.7	2.0	0.7
Maternal smoking around birth	2.5	3.6	9.3	0.9	3.1	1.9	1.9	2.1	2.7	2.5	0.1	-0.4	1.0
Wheeze or whistling in the chest in last year	2.5	4.5	16.1	1.6	2.1	2.4	4.0	0.7	0.9	1.3	3.3	1.0	1.3
Hayfever, allergic rhinitis or eczema	2.4	5.3	28.2	2.9	0.4	1.3	0.9	1.3	-2.0	-0.8	2.2	1.7	5.3
Heart attack	2.4	3.1	10.7	-0.9	-2.1	-3.1	-0.8	-3.3	-2.1	-0.7	0.3	0.1	-0.4
Medication: Paracetamol	2.4	4.0	15.7	-1.3	-1.7	-2.0	-0.6	-3.7	-0.8	-0.9	0.3	0.1	-4.0
Commuting to job workplace: Car/motor vehicle	2.4	2.8	4.8	0.3	2.1	1.3	2.2	1.0	2.2	2.1	1.8	0.8	1.5
Medication: Atorvastatin	2.4	2.9	6.7	2.6	0.3	-2.0	1.5	-0.0	2.3	2.5	1.5	-0.2	1.7
Heart attack/myocardial infarction (self-reported)	2.4	3.1	10.3	-0.9	-2.2	-2.9	-1.0	-3.2	-2.1	-0.9	0.4	0.4	-0.4
LDL Cholesterol	2.3	3.7	8.7	-2.4	-3.0	-2.6	-1.6	-0.6	-1.0	-2.9	-1.7	0.4	0.7
Mouth/teeth dental problems	2.3	3.6	12.3	0.3	-2.4	-2.1	-3.1	-0.5	1.4	0.1	-3.5	-0.4	1.1
Medication: Ventolin 100micrograms inhaler	2.3	3.0	9.7	1.4	0.4	1.3	0.6	1.8	-0.7	0.1	2.1	2.9	3.1
Fluid intelligence score	2.1	4.3	9.7	0.1	-2.6	-2.1	-3.1	-0.7	-0.9	-1.9	-2.9	-2.4	-1.8
Father’s age at death	2.1	2.9	9.4	-1.9	-1.0	0.3	-1.5	0.1	-0.1	-2.1	-3.1	-2.2	-1.6
Number of live births	2.1	3.0	8.5	0.2	2.9	2.2	1.9	2.1	1.3	1.6	0.7	-0.2	-2.0
Comparative body size at age 10	2.1	5.7	14.8	2.0	3.9	3.6	2.6	2.3	2.2	2.6	0.5	-1.0	-0.1
Number of operations (self-reported)	2.1	3.1	10.0	-1.1	-1.2	-2.3	0.5	-1.1	1.5	-0.0	-1.5	-2.6	-3.2
Pain experienced in last month	2.1	3.5	11.2	1.3	1.6	2.0	0.2	3.0	0.9	1.5	1.5	1.4	3.3
Schizophrenia (2018)	2.0	4.1	11.8	1.7	1.2	2.1	0.6	1.3	1.8	1.7	2.3	2.7	3.4
Ulcerative Colitis	2.0	2.9	8.4	1.2	2.6	2.9	-0.3	0.0	2.4	1.9	-0.5	-1.8	0.3
Frequency of depressed mood in last 2 weeks	2.0	2.8	11.1	-0.2	-2.3	-3.3	0.3	-2.3	1.1	-0.6	1.2	0.3	-1.9
Hayfever/allergic rhinitis (self-reported)	2.0	2.7	6.4	2.5	1.3	1.2	1.9	2.4	0.6	0.2	1.7	-0.5	2.1
Mean time to correctly identify matches	2.0	3.8	9.0	-1.4	-2.0	0.2	-3.0	-1.2	-2.7	-2.8	-1.4	-0.3	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.4	6.2	2.1	0.1	-0.9	2.4	-2.5	1.0	0.9	1.8	-1.1	-0.6
Commuting to job workplace: Walk	2.0	2.2	4.4	-0.6	-1.4	-1.0	-1.7	-1.2	-2.1	-1.2	-2.1	-2.0	-0.3
Average weekly champagne plus white wine intake	2.0	2.8	6.7	0.1	-2.4	-1.5	-1.8	-2.6	-1.4	-2.5	-0.2	0.8	1.0
Ever used hormone-replacement therapy (HRT)	1.9	2.5	6.3	0.0	2.1	2.5	1.9	1.6	1.3	0.8	-0.4	-2.1	-0.9
Bipolar Disorder or Schizophrenia	1.8	4.5	12.1	0.9	2.6	3.5	1.0	1.4	1.3	1.5	2.2	2.5	2.7
Reaction Time	1.8	3.4	11.2	-1.0	-1.9	0.4	-3.0	-0.1	-3.3	-2.4	-0.7	0.7	-1.4
Age at First Birth	1.8	2.6	10.1	-0.9	-1.6	0.1	-1.0	-0.0	-2.2	-3.2	-0.7	1.1	2.2
HDL Cholesterol	1.8	3.0	12.1	2.2	2.0	3.5	1.0	1.6	0.7	1.1	1.5	-0.1	1.2
Neuroticism (2016)	1.8	2.5	9.9	-0.1	-0.6	-3.0	1.1	-3.1	1.8	0.5	-1.1	0.7	-0.0
Smoking Status	1.8	4.3	12.5	0.6	3.3	2.1	3.5	0.8	1.7	2.5	0.7	-1.2	-1.8
Chronic bronchitis/emphysema (father)	1.8	2.1	4.9	0.7	1.7	1.7	2.2	-0.5	1.9	0.9	2.1	-0.2	1.1
High blood pressure (mother)	1.8	2.6	7.4	1.6	-2.3	-2.7	0.3	-1.2	1.7	-0.3	-0.5	-1.9	-1.6
Chest pain or discomfort	1.8	2.5	12.3	0.3	1.4	0.3	3.5	-0.9	1.4	1.4	2.3	0.6	-0.6
Eye problems/disorders: Cataract	1.8	2.1	5.5	-0.9	-1.7	-2.3	-2.0	-1.6	0.1	-0.7	-1.6	-0.2	-1.6
Schizophrenia (2014)	1.7	3.8	8.9	0.8	1.6	1.7	1.2	1.2	1.6	2.0	2.6	2.7	3.0
Diabetes (mother)	1.7	2.2	7.7	0.7	-2.5	-2.8	1.0	-1.6	0.8	-0.6	-0.3	-1.7	-0.6
Qualifications: None of the above	1.7	3.6	11.6	2.4	1.9	1.3	3.4	1.2	0.3	2.1	2.0	1.7	0.2
Shortness of breath walking on level ground	1.7	2.0	6.0	-0.7	1.6	1.9	1.7	0.2	-0.5	0.2	2.4	0.5	-2.0
Ever smoked	1.7	3.0	8.1	0.4	2.5	2.7	2.9	0.7	1.7	1.0	-0.4	-1.2	-1.6
Lupus	1.6	2.5	5.5	-0.9	-2.3	-1.8	-1.4	-0.3	-1.2	-2.2	-2.0	0.4	1.7
Pain all over the body in last month	1.6	1.7	4.6	1.1	0.8	0.3	2.1	-0.9	1.5	1.7	1.2	0.0	1.9
Length of working week for main job	1.6	1.7	4.8	1.2	0.9	-0.5	1.5	-0.8	1.5	1.9	0.5	-1.1	2.2
Leg fat percentage (right)	1.6	5.7	14.0	1.9	3.3	2.4	3.7	1.3	0.3	2.5	2.4	1.9	2.2
Medication: Omeprazole	1.6	1.9	7.0	1.1	0.1	-1.2	2.1	-0.4	-0.1	1.9	2.6	0.5	-0.8
Commuting to job workplace: Public transport	1.6	1.9	6.0	-0.4	-2.0	-1.2	-1.4	-1.3	-1.7	-2.4	-0.5	0.6	-0.1
Leg fat percentage (left)	1.6	6.0	12.5	2.1	3.5	3.0	3.5	1.3	0.3	2.5	2.4	1.7	2.1
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	9.5	-1.1	-1.4	-0.3	-0.2	-2.0	-3.1	-2.0	-0.4	0.1	0.1
Bipolar Disorder (2018)	1.5	2.3	10.1	-0.2	3.2	2.9	1.2	0.8	0.4	1.2	0.9	0.6	-0.0
Alzheimer’s Disease (in father)	1.5	1.6	3.1	0.3	1.8	1.6	1.5	0.2	0.5	1.4	1.5	1.7	0.7
Number of treatments/medications taken	1.5	2.7	12.8	-0.9	-0.9	-1.9	0.9	-2.5	0.3	0.1	-0.4	-1.1	-3.6
Qualifications: CSEs or equivalent	1.5	2.0	10.1	-3.2	-0.6	-0.6	-1.6	-1.1	-1.2	-1.4	-1.0	0.9	-0.2
Waist circumference	1.5	5.5	19.5	2.3	3.4	3.3	4.4	0.6	-0.1	1.6	2.3	-0.1	-0.0
Mouth/teeth dental problems: Dentures	1.5	2.5	8.8	0.5	2.0	0.4	2.8	-0.2	-0.1	1.8	3.0	-0.1	-0.5
Medication: Seretide 50 evohaler	1.5	1.8	7.0	1.1	0.2	0.1	0.4	0.6	-0.0	0.6	2.5	1.6	2.6
Leg fat mass (right)	1.5	5.9	13.4	3.0	3.4	3.0	3.7	0.9	0.3	2.6	2.3	1.2	1.4
Suffer from ‘nerves’	1.5	2.4	6.3	0.2	2.5	2.3	2.1	0.8	0.8	0.7	1.7	1.8	0.3
Medication: Aspirin	1.5	2.0	7.4	-0.5	-0.9	-2.7	0.7	-1.9	0.7	1.5	0.7	-0.3	-2.0
Hearing aid user	1.5	1.7	3.7	-1.9	-1.8	-1.2	-1.6	-1.1	-0.9	-1.7	-0.2	1.0	-0.4
Leg fat mass (left)	1.5	6.0	11.8	3.1	3.4	3.4	3.4	0.9	0.2	2.6	2.2	1.0	1.3
Primary Biliary Cirrhosis	1.4	2.1	4.9	-0.4	-1.7	-1.9	-1.3	-1.9	-1.6	-0.9	0.6	0.0	-2.2
BMI	1.4	8.1	21.0	3.6	4.0	4.6	3.4	1.0	-1.1	2.3	2.3	1.3	2.3
Lung FEV1/FVC ratio	1.4	7.2	25.8	-0.2	3.2	5.1	3.2	4.9	-0.1	-0.4	0.1	-0.1	1.0
Ever had hysterectomy (womb removed)	1.4	1.6	4.8	0.3	1.5	1.9	1.2	2.2	0.6	0.7	-0.5	-0.6	-1.4
Supplements: Zinc	1.4	1.5	5.9	-0.4	-0.7	-1.7	-0.2	0.6	1.8	0.8	-0.9	0.0	-2.4
Blood clot in the leg (DVT)	1.4	1.8	7.6	-0.9	-1.2	-0.1	0.1	-2.1	-2.8	-1.8	-0.7	-0.4	0.3
Number of children fathered	1.4	1.6	7.6	0.6	1.4	0.4	0.8	0.1	2.8	1.4	-0.7	-1.6	0.3
Medication: Aspirin	1.4	1.8	5.6	-0.5	-0.6	-2.4	0.9	-1.9	0.7	1.5	0.5	-0.3	-2.0
Average weekly red wine intake	1.4	2.1	9.5	3.1	1.0	0.7	1.0	0.8	1.4	1.1	1.7	-0.2	1.4
Fractured/broken bones in last 5 years	1.4	1.8	4.3	1.4	1.2	1.1	2.1	1.4	1.7	1.6	1.3	0.0	0.6
Alcohol drinker status: Previous	1.4	1.5	4.5	-0.4	-1.0	-1.1	1.5	-1.3	0.6	-0.3	2.1	1.1	-1.8
Blood Eosinophil Count	1.3	9.7	48.3	3.0	0.2	1.5	-0.1	1.4	-4.4	-1.4	2.6	2.6	7.0
Body mass index (BMI)	1.3	5.7	13.5	3.1	3.4	3.7	3.2	1.0	-0.4	2.3	2.1	0.9	0.7
Hip circumference	1.3	5.7	18.7	4.3	3.0	3.6	2.3	0.8	-0.2	2.1	2.2	0.3	0.4
Alcohol intake versus 10 years previously	1.3	1.9	5.5	-0.7	-1.3	-0.8	0.5	-2.3	0.1	-0.8	-1.4	-2.3	-1.7
Qualifications: A levels/AS levels or equivalent	1.3	2.9	7.5	-0.4	-2.7	-2.1	-2.1	-0.5	-1.2	-2.1	-1.7	-1.7	-0.3
Exposure to tobacco smoke at home	1.3	1.4	4.8	0.6	1.5	2.0	0.8	1.2	0.4	0.7	2.2	0.6	-0.1
Tense / ‘highly strung’	1.3	2.2	10.9	0.5	0.4	0.1	2.3	-0.1	0.6	0.2	1.3	1.8	3.3
Ever highly irritable/argumentative for 2 days	1.3	1.5	6.1	1.6	1.0	-0.2	1.6	0.1	-0.6	1.4	2.5	0.3	-0.6
Body fat percentage	1.3	5.2	15.2	2.3	3.0	2.0	3.9	0.2	-0.1	2.4	2.9	1.1	1.9
Miserableness	1.3	2.3	6.1	-2.3	-1.0	-2.5	-1.3	-0.9	1.3	-0.9	-1.6	1.0	-1.5
Average weekly beer plus cider intake	1.3	1.8	4.3	0.8	1.9	0.8	2.0	0.2	0.3	2.1	2.0	-0.4	0.9
Verbal and Numeric Reasoning (VNR)	1.2	2.9	7.5	-0.1	-2.1	-2.7	-2.2	-0.5	-1.1	-1.1	-1.3	-1.7	-2.2
Bipolar Disorder (2011)	1.2	1.1	5.7	-0.7	0.0	0.0	0.7	0.0	0.1	0.0	2.4	2.2	0.0
Fed-up feelings	1.2	2.2	9.3	-1.0	-1.6	-3.1	0.5	-2.1	0.6	-0.5	0.9	1.1	-1.4
Stomach or abdominal pain in last month	1.2	1.5	4.5	0.3	-1.4	-1.6	0.7	-2.1	-0.9	-0.9	-0.3	-1.3	-1.6
Sitting height	1.2	8.6	24.9	1.2	-4.2	-5.0	-3.8	-3.2	-1.7	-0.8	-0.6	-0.8	-3.6
Arm fat percentage (right)	1.2	4.7	13.0	2.7	2.7	2.5	3.6	0.3	-0.6	1.7	2.5	0.6	1.6
Prospective memory result	1.2	1.5	4.1	-0.5	0.6	1.0	1.1	1.5	1.7	0.6	1.7	2.0	0.5
Arm fat mass (right)	1.2	5.1	12.4	3.4	2.8	2.8	3.5	0.3	-0.3	2.0	2.5	0.5	0.8
Peak expiratory flow (PEF)	1.2	2.7	8.5	2.9	2.0	2.1	1.6	1.8	-0.1	1.6	0.8	-1.0	-0.2
High blood pressure (siblings)	1.2	1.7	7.2	-0.5	-2.0	-2.7	-0.2	-0.4	1.0	-0.6	-0.6	-0.4	-1.8
Number of full brothers	1.2	1.6	5.1	1.2	1.3	1.5	2.3	1.0	0.7	0.9	0.6	-1.1	-1.1
Whole body fat mass	1.2	5.0	13.4	3.2	2.8	2.3	3.7	0.1	0.1	2.2	2.4	0.5	1.3
Ever had bowel cancer screening	1.2	1.4	4.0	-0.6	-0.2	-2.0	1.3	-1.1	0.5	0.4	-1.3	-1.8	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	4.5	-2.0	-0.8	-1.3	-0.0	-2.1	0.4	-0.2	-1.2	0.2	-0.3
Back pain experienced in last month	1.2	1.8	7.1	1.0	0.3	-0.2	1.5	-1.9	0.3	0.3	1.5	-1.1	-2.7
Arm fat mass (left)	1.2	4.9	12.0	3.3	2.8	2.7	3.5	0.3	-0.3	2.1	2.4	0.5	0.7
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.4	1.1	0.9	-0.5	1.5	1.0	1.5	1.8	1.7	-1.0	0.6
Irritability	1.2	2.1	3.7	-1.6	-1.6	-1.7	-0.6	-1.9	-1.8	-1.9	-0.5	1.1	0.2
Unable to work because of sickness or disability	1.2	1.5	6.3	0.5	0.8	0.4	1.4	0.3	0.9	2.0	2.5	0.0	0.8
Commuting to job workplace: Cycle	1.2	1.4	6.2	-0.8	-1.9	-0.7	-0.6	-0.6	-1.4	-2.5	-0.9	0.1	0.2
Depressed Affect (Nagel 2018)	1.1	2.4	9.3	-1.5	-1.3	-3.0	-0.3	-1.9	1.2	-0.5	-0.1	1.2	-1.9
Depression (Nagel 2018)	1.1	1.7	5.0	-0.3	-2.0	-2.2	0.1	-1.7	0.8	-0.7	0.9	1.2	-1.4
Current tobacco smoking	1.1	1.7	6.3	-0.4	0.8	-0.5	2.5	-0.9	1.7	1.4	1.2	-0.3	-1.7
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.8	-0.5	-1.5	-1.4	-0.1	-1.0	-2.0	-1.2	0.3	-0.6	-1.4
Medication: Levothyroxine sodium	1.1	1.9	4.8	1.5	-1.4	-1.6	1.6	0.2	1.7	-0.0	0.7	-2.2	-1.2
Hair/balding pattern: Pattern 2	1.1	1.4	2.7	-1.2	-1.6	-0.8	-0.8	-1.7	-0.7	-1.6	-1.6	0.1	-0.3
Falls in the last year	1.1	1.5	9.3	0.4	0.2	0.1	3.0	-0.7	0.5	0.3	1.7	-0.6	-1.3
Heart disease (mother)	1.1	1.4	3.5	-0.7	-1.9	-1.8	-0.4	-0.1	-0.7	-1.1	-1.0	-0.6	-1.7
Supplements: Vitamin C	1.1	1.3	2.9	-1.0	-1.0	-1.4	-1.6	0.6	-1.5	-1.1	-0.5	0.1	-1.7
Arm fat percentage (left)	1.1	4.5	13.1	2.5	2.9	2.6	3.6	0.4	-0.4	1.7	2.3	0.3	1.5
Long-standing illness, disability or infirmity	1.1	1.7	5.9	1.5	0.2	0.1	2.0	-0.1	2.4	0.8	1.4	-1.4	0.2
Medication: Gliclazide	1.1	1.3	3.8	-0.3	1.3	1.9	1.2	-0.4	-0.8	-0.5	-1.2	-1.8	-0.3
Ever had prostate specific antigen (PSA) test	1.1	1.3	6.0	0.6	-0.4	-1.3	-0.7	-0.7	2.5	0.8	-1.3	-0.7	-0.9
Heart disease (siblings)	1.1	1.4	5.7	0.2	0.7	-0.4	2.4	-0.8	1.2	1.4	1.0	1.5	0.5
Body Mass Index (BMI) (2010)	1.0	1.4	5.2	0.0	2.3	2.2	0.8	1.1	-0.0	0.8	0.8	0.5	0.6
Fasting Glucose	1.0	1.2	2.8	-1.5	-0.2	0.1	-1.7	1.4	1.0	0.3	-1.5	-0.9	0.2
Type 2 Diabetes (T2D) (2012)	1.0	1.1	2.6	0.0	1.1	1.2	-0.6	1.4	-0.5	1.5	1.1	1.6	0.4
Blood Platelet Count	1.0	11.2	62.7	0.3	1.1	-2.5	3.9	0.3	7.9	3.4	-1.5	-0.7	-3.4
Relative age of first facial hair	1.0	2.1	14.3	-1.1	0.2	0.1	0.9	0.2	0.5	-0.9	-1.8	-0.2	3.8
Trunk fat percentage	1.0	4.1	13.3	2.2	2.4	1.5	3.6	-0.4	-0.1	1.9	2.6	0.5	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.7	-0.6	-1.9	-1.9	-0.1	-1.7	0.2	-0.8	-0.0	0.6	-1.3
Supplements: Glucosamine	1.0	1.3	4.0	-1.3	0.2	-1.4	-0.7	-0.1	-0.0	0.1	-2.0	-1.8	-1.1
Trunk fat mass	1.0	4.2	11.9	3.0	2.4	1.9	3.4	-0.4	-0.1	2.0	2.4	0.3	1.4
Hearing difficulty/problems with background noise	1.0	1.6	10.8	0.6	0.4	0.7	0.4	1.9	0.2	-0.3	0.5	0.2	-3.3
Neuroticism score	1.0	2.0	8.6	-1.2	-0.9	-2.9	0.8	-2.5	1.1	-0.4	-0.1	0.9	-0.4
Weight	1.0	4.7	16.8	4.1	2.5	2.7	3.1	-0.0	-0.1	2.0	1.9	-0.0	0.2
Time employed in main current job	1.0	1.1	6.6	1.1	0.3	0.8	1.2	0.9	-0.2	0.6	2.6	0.4	0.0
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	5.3	-0.7	-0.4	-1.4	1.9	0.4	1.6	0.3	-0.1	-1.2	-2.3
Depression (self-reported)	1.0	1.2	4.7	0.9	-0.6	-0.8	1.0	-2.2	0.3	-0.4	1.1	1.7	-0.6
Health satisfaction	1.0	1.2	5.2	-0.3	1.2	1.5	0.8	-0.8	-0.1	1.1	0.7	2.3	0.5
Alcohol intake frequency.	1.0	2.3	13.7	-1.0	-1.2	-1.2	0.5	-1.7	1.2	-0.5	0.5	-0.5	-3.7
Breast cancer (self-reported)	1.0	1.2	4.2	-1.7	-0.2	0.5	-0.8	-0.6	-0.6	-1.5	0.8	2.0	0.8
Ever taken oral contraceptive pill	1.0	1.1	3.6	-0.2	1.5	1.9	-0.3	1.8	0.0	0.1	0.7	0.7	-1.1
Medication: Bendroflumethiazide	1.0	1.6	3.4	1.4	0.8	1.5	1.7	-1.1	1.4	0.5	1.1	-0.0	1.8
Schizophrenia vs Biploar Disorder	0.9	1.2	2.5	0.4	-1.2	-1.6	0.1	0.0	1.3	0.8	1.1	1.4	1.5
Mean Putamen Volume	0.9	1.1	3.5	0.5	-1.9	-0.8	-0.2	-1.0	-0.9	-1.4	0.3	-0.0	-1.5
Neuroticism	0.9	2.1	11.1	-0.3	-0.6	-3.3	1.2	-1.8	1.8	0.2	0.3	0.8	-0.5
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.8	0.0	1.9	1.6	0.5	0.6	-0.3	1.4	0.5	1.0	-0.4
Medication for hormone replacement therapy	0.9	1.0	3.0	0.6	0.8	1.4	0.2	0.6	-0.3	0.2	0.1	-1.7	-1.7
Impedance of leg (right)	0.9	4.3	19.4	-3.2	-2.1	-4.4	-0.6	0.1	1.2	-0.5	-0.1	1.6	2.2
Taking other prescription medications	0.9	1.3	4.4	-0.2	1.5	1.6	2.1	-0.8	0.8	1.0	1.0	0.6	0.5
Had menopause	0.9	1.1	6.8	-2.6	0.9	-0.4	1.1	0.7	0.7	0.7	-0.2	-0.6	0.1
Hair/balding pattern: Pattern 3	0.9	1.4	3.7	-1.9	-1.0	-1.0	-1.9	-1.0	-0.5	-0.9	-1.5	-0.1	-0.3
Pulse rate	0.9	1.5	7.4	-0.9	0.3	2.7	-0.4	0.8	-0.9	-1.7	-1.1	-0.9	-0.8
Illnesses of mother	0.9	1.1	3.5	-1.0	0.9	1.6	-0.3	0.1	-1.9	-0.5	1.0	1.4	0.5
Impedance of arm (left)	0.9	4.1	14.4	-2.4	-2.9	-3.8	-0.5	-1.5	-0.1	-2.3	-0.2	-1.3	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	4.9	1.3	0.7	0.2	1.0	0.3	2.2	1.2	-0.4	-1.1	-1.6
Qualifications: College or University degree	0.9	2.9	13.0	-1.0	-2.1	-2.0	-3.6	-0.2	-0.0	-1.3	-1.6	-0.7	-1.1
Emphysema/chronic bronchitis	0.9	1.0	2.7	-0.5	0.7	0.7	1.6	0.2	1.2	1.3	0.6	0.8	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	3.5	-0.4	-0.7	0.4	-0.4	-0.1	-0.9	-1.6	-1.9	0.9	1.5
Risk taking	0.9	1.4	4.9	2.0	0.2	0.5	2.2	0.1	-0.5	-0.4	1.7	-0.1	1.1
Medication: Omeprazole (e.g. Zanprol)	0.9	1.2	4.3	0.8	-0.0	-0.7	1.9	-0.2	-0.1	1.1	2.1	-0.1	-1.1
Coronary Artery Disease (CAD)	0.8	0.9	3.3	-0.6	1.8	1.2	1.1	0.0	1.1	0.0	1.2	0.3	0.0
Lung FVC	0.8	4.1	11.2	-3.3	-0.2	-0.3	-2.6	1.7	-0.9	-0.9	-3.0	-1.7	-2.6
Average weekly spirits intake	0.8	0.9	1.9	-0.2	-1.3	-1.2	0.6	-1.3	-0.2	-0.9	-1.4	-1.1	-0.1
Relative age voice broke	0.8	1.2	7.1	-0.0	-0.6	-0.4	-0.5	-1.2	-0.7	-0.6	-0.9	0.8	2.7
Financial difficulties in last 2 years	0.8	1.0	2.9	-0.2	-0.9	0.1	0.8	-1.2	-1.0	-0.5	1.7	1.2	-1.3
Illnesses of siblings	0.8	1.1	3.8	0.9	0.8	1.9	-0.8	0.6	-1.7	-0.5	0.1	-0.2	1.4
Impedance of arm (right)	0.8	3.7	14.0	-1.8	-3.2	-3.7	-0.5	-1.5	-0.1	-2.0	0.5	-0.6	1.7
Medication: Cholesterol lowering	0.8	1.3	4.7	-0.2	-1.7	-2.2	-0.6	-1.6	-0.8	-0.3	-0.3	1.0	-0.8
Pulse wave reflection index	0.8	1.0	3.0	0.2	0.8	-0.3	-0.8	0.2	1.3	1.6	-1.7	-0.3	-0.9
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	4.0	-0.1	-1.7	-2.0	-1.1	-1.8	-0.5	-0.6	-0.7	-0.2	0.4
Age at first live birth	0.8	1.4	4.6	-0.8	-1.9	-2.1	-1.5	-0.4	-0.1	-0.8	-1.2	-0.5	-0.3
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.5	0.2	1.1	1.9	1.0	0.7	0.1	0.5	-0.5	-1.6	-0.5
Had major operations	0.8	0.9	2.9	-0.6	-1.1	-1.4	-0.8	-0.8	-0.4	-0.3	-0.5	-1.0	-1.7
Leg pain on walking	0.8	1.1	2.7	-0.8	-1.5	-1.6	-0.6	-0.9	-1.0	-0.8	0.3	0.8	1.1
Mood swings	0.8	1.5	3.8	-2.0	-1.2	-1.8	-0.6	-1.4	0.3	-1.1	-0.6	0.6	-1.6
Loneliness, isolation	0.8	1.2	3.6	-0.1	-1.0	-1.7	0.6	-1.4	-0.1	-0.3	1.9	1.3	-0.6
Osteoporosis (self-reported)	0.8	0.9	3.0	-1.6	-0.4	-0.2	0.5	0.2	0.7	-0.6	-1.2	-1.7	-1.1
Supplements: Calcium	0.8	0.8	2.1	-0.8	0.1	-0.8	1.0	0.7	1.0	0.2	-1.1	-1.1	-1.5
Impedance of whole body	0.8	3.9	16.6	-2.9	-2.5	-4.1	-0.9	-0.9	0.6	-1.4	-0.0	-0.0	1.8
Crohns Disease (2012)	0.7	1.1	4.6	0.4	-0.2	-0.0	-1.3	0.0	0.4	-0.3	-0.7	-2.1	-1.9
Hypothyroidism (self reported)	0.7	1.5	4.3	1.6	-1.0	-1.7	0.9	-0.1	2.1	1.4	1.0	-0.3	-0.8
Sensitivity / hurt feelings	0.7	1.2	2.9	-1.4	0.0	-1.6	-0.5	-1.7	0.4	-1.0	-1.0	1.1	-0.7
Angina	0.7	0.9	3.6	0.4	0.9	-0.2	0.5	-1.9	0.0	1.0	1.4	0.6	0.7
Pack years adult smoking proportion	0.7	1.1	4.0	0.9	1.0	1.6	0.7	2.0	0.3	0.5	1.0	-0.1	-0.5
Leg fat-free mass (left)	0.7	3.6	21.4	4.6	1.3	2.2	1.5	-0.6	-0.4	1.4	0.9	-1.1	-1.1
Hand grip strength (right)	0.7	2.0	4.7	0.5	-1.5	-1.5	-1.7	-1.4	-1.6	-0.7	-2.2	-1.1	-1.0
Serious illness, injury or assault to yourself	0.7	0.9	4.4	-0.4	-0.9	-0.4	-0.3	-0.3	-0.9	-0.0	1.4	0.3	-2.1
Impedance of leg (left)	0.7	3.4	11.1	-3.1	-1.7	-3.3	-1.0	0.1	1.1	-0.7	-0.2	1.4	2.2
Alcohol usually taken with meals	0.7	1.1	3.2	-0.6	-0.9	-0.9	-1.2	-0.4	0.6	-1.1	-1.8	-1.4	-0.8
Happiness	0.7	0.8	2.0	1.0	-1.4	-1.3	-0.3	-0.4	0.7	-0.4	0.9	1.4	-0.2
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	3.4	1.6	-0.7	-1.0	1.6	-0.2	1.9	1.0	0.8	-1.3	-0.6
Neck or shoulder pain in last month	0.7	1.0	3.6	-1.9	-0.0	0.6	0.7	-0.7	-0.7	-1.7	-0.3	0.1	-1.1
Angina (self-reported)	0.7	0.9	3.3	0.4	1.0	-0.1	0.5	-1.8	-0.1	1.0	1.5	0.6	0.6
Age at last live birth	0.7	1.0	4.4	1.2	-1.3	-0.7	-0.4	-0.2	0.1	-0.3	-1.1	-2.1	-0.2
Leg fat-free mass (right)	0.7	3.6	21.0	4.6	1.3	2.7	1.0	-0.7	-0.5	1.0	0.6	-1.4	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.6	-0.4	-0.1	0.1	-0.1	-0.1	-0.8	0.3	1.9	1.4	-1.5
Smoking status: Current	0.7	1.1	3.3	-0.4	0.3	-0.6	1.8	-0.9	1.6	0.9	0.6	-0.1	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	6.3	-1.8	-0.2	0.5	-1.0	1.2	-0.9	-1.4	-2.5	-0.4	0.1
Leg predicted mass (right)	0.7	3.6	21.2	4.6	1.2	2.6	1.0	-0.7	-0.5	1.0	0.6	-1.4	-1.2
Financial situation satisfaction	0.7	0.8	2.8	1.0	-0.6	0.3	-0.7	-0.4	-1.4	-0.2	1.7	1.2	0.1
Medication: Lisinopril	0.7	0.9	2.7	0.3	0.6	-0.0	1.3	1.1	1.6	0.5	-1.2	-0.3	1.2
Arm fat-free mass (left)	0.7	3.6	16.0	4.0	2.0	2.2	1.5	0.3	0.2	2.2	1.3	0.8	-1.2
Worry (Nagel 2018)	0.6	1.2	6.1	0.2	1.3	0.1	2.5	-0.0	0.5	0.5	1.4	1.1	0.4
Crohns Disease (2017)	0.6	1.3	4.2	0.1	0.2	0.4	-1.2	1.3	1.0	0.4	-0.5	-1.9	-2.1
Irritable Bowel Disease (IBD)	0.6	1.5	5.6	0.2	0.7	1.1	-1.3	0.9	1.5	0.5	-0.9	-2.4	-1.1
Ulcerative Colitis (UC)	0.6	1.1	3.9	0.6	0.6	1.2	-0.8	-0.1	1.5	0.3	-0.9	-2.0	0.7
Rheumatoid Arthritis	0.6	0.8	2.3	0.9	0.8	-0.4	1.2	0.0	0.1	1.5	1.5	0.7	-0.2
Heel T-Score	0.6	4.9	16.0	0.8	2.3	2.5	1.7	0.7	1.4	0.9	-0.5	-4.0	-3.7
Waist Hip Ratio (WHR)	0.6	2.6	15.1	-2.1	0.9	-0.1	3.9	0.5	0.4	-0.2	1.4	-1.1	-1.4
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.5	-0.9	-0.0	0.5	1.1	-0.0	0.7	-0.3	-0.6	-1.6	-1.3
Systolic blood pressure, automated reading	0.6	1.6	4.7	1.4	0.2	-1.5	1.0	1.1	1.6	2.2	0.9	1.1	0.5
Medication: Metformin	0.6	0.9	2.8	-0.1	1.6	1.7	0.4	0.4	0.7	0.7	-0.3	-1.4	-0.4
Leg predicted mass (left)	0.6	3.4	20.9	4.6	1.2	2.0	1.4	-0.7	-0.4	1.3	0.9	-1.1	-1.1
Number of incorrect matches in round	0.6	1.1	5.7	0.5	1.1	1.0	0.4	0.9	0.1	0.6	2.4	0.9	-0.4
Had other major operations	0.6	0.8	4.6	-1.2	-0.0	-1.0	0.3	-2.1	-0.2	-0.3	-0.2	-0.0	-0.6
Forced vital capacity (FVC)	0.6	2.2	5.7	-1.2	-1.2	-0.9	-2.1	-0.4	-1.2	-1.4	-2.4	-1.8	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	4.0	1.4	1.3	2.0	1.3	1.4	0.1	-0.1	-0.6	-1.6	-0.1
Lung cancer (father)	0.6	0.7	2.2	0.7	0.8	0.9	1.3	0.5	0.0	0.9	1.5	-0.2	-0.1
Forced vital capacity (FVC), Best measure	0.6	2.1	5.1	-0.7	-2.0	-1.9	-1.9	-0.8	-0.6	-1.3	-2.3	-1.1	-0.8
Exposure to tobacco smoke outside home	0.6	0.8	1.9	-0.9	-0.2	0.5	-0.8	1.4	-0.7	-0.8	-1.1	0.7	-1.1
Worry too long after embarrassment	0.6	0.9	2.6	-1.3	-0.6	-1.2	-0.9	-1.1	-0.0	-0.6	-0.4	1.6	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.2	0.0	0.3	0.8	-0.4	-0.3	-1.5	-0.4	0.9	1.4	0.9
Qualifications: nursing, teaching	0.6	1.0	4.0	-0.6	-0.7	0.1	-0.7	0.5	0.9	-1.1	-1.4	0.1	2.0
Number of self-reported non-cancer illnesses	0.6	1.1	6.0	0.1	0.0	-0.4	2.4	-0.5	1.6	0.4	1.0	-0.7	-0.8
Guilty feelings	0.6	0.8	2.9	-0.2	-0.1	-1.2	1.7	-1.0	1.4	-0.2	-0.0	0.6	0.8
Wears glasses or contact lenses	0.6	0.7	1.5	-1.0	1.2	1.1	1.0	-0.0	-0.7	0.2	1.1	0.6	0.7
Eye problems/disorders: Glaucoma	0.6	0.8	1.9	1.2	-0.5	-0.1	-0.9	0.6	-0.4	-0.8	-1.4	-1.3	-0.5
High cholesterol (Self-reported)	0.6	1.0	2.4	-0.8	-1.5	-1.6	-0.0	-1.3	-0.4	-1.3	-0.7	0.3	-0.0
Alcohol drinker status: Never	0.6	0.7	2.2	-0.1	1.0	0.2	0.3	-0.2	0.8	1.3	1.5	1.3	0.2
Basal metabolic rate	0.6	3.2	18.8	4.3	1.3	2.2	1.4	-0.3	-0.1	1.4	1.0	-0.3	-1.1
Diastolic blood pressure, automated reading	0.6	1.9	6.3	1.6	0.8	-0.6	1.0	-0.1	2.5	2.4	0.7	1.1	1.1
Cholesterol lowering medication	0.6	1.0	3.8	0.2	-0.8	-2.0	1.1	-0.6	0.8	0.4	0.6	-1.4	-0.5
Pack years of smoking	0.6	0.9	3.7	0.6	1.1	1.6	0.6	1.9	0.4	0.3	0.8	-0.3	-0.6
Arm predicted mass (left)	0.6	2.9	13.7	3.7	1.6	2.1	1.2	0.0	-0.1	1.9	1.1	0.7	-1.3
Ovarian Cancer	0.5	0.7	1.3	-0.4	-1.1	-0.0	-1.1	-0.6	-1.0	-1.1	-0.8	1.0	-0.7
Hair Pigment	0.5	13.5	25.9	5.1	4.7	4.7	4.0	3.8	1.4	3.1	4.7	0.1	0.9
Hearing difficulty/problems: Yes	0.5	0.7	1.8	1.3	-0.5	0.3	0.8	1.4	0.0	-0.6	1.2	-0.4	-0.7
Diabetes (father)	0.5	0.6	1.5	0.4	1.0	0.4	0.5	0.6	-0.3	1.0	0.7	1.2	-0.8
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	2.4	0.0	0.6	0.5	0.4	0.3	1.3	0.2	-0.5	-1.5	-0.0
Medication: Atenolol	0.5	0.6	1.5	0.5	-1.1	-0.7	0.9	-1.2	0.5	-0.9	-0.4	-0.8	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.6	-0.6	0.1	0.0	1.9	-1.2	0.5	-0.6	0.5	-1.0	-1.1
Medication: Ramipril	0.5	0.7	3.0	0.2	0.1	0.2	0.5	-1.2	0.6	0.5	1.7	-0.3	-1.1
Worrier / anxious feelings	0.5	1.0	3.4	-0.1	0.8	-0.7	1.9	-0.7	1.6	0.3	0.4	-1.2	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.9	0.5	0.7	1.1	0.2	1.4	0.7	0.2	-0.4	-0.6	-1.0
Medication: Blood pressure	0.5	0.9	2.6	1.6	-0.6	0.0	0.5	-1.5	1.3	-0.1	0.4	1.1	0.5
Arm predicted mass (right)	0.5	2.5	11.8	3.4	1.7	1.9	1.1	0.1	0.4	1.8	0.3	-0.1	-1.5
Pulse rate, automated reading	0.5	1.7	11.1	-0.3	1.0	3.3	0.4	0.9	-0.7	-1.3	-0.5	1.1	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.1	-0.6	0.6	0.4	-0.3	-0.3	-0.3	0.2	-1.3	-1.4	-1.2
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	2.4	0.4	0.9	-0.3	0.3	-0.2	0.4	0.4	-1.4	-0.8	1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	3.5	1.1	-1.8	-1.9	-0.9	-0.5	0.2	-0.5	-0.3	-0.6	-0.1
Whole body fat-free mass	0.5	2.8	17.4	4.2	1.1	1.9	0.9	-0.4	0.1	1.3	0.6	-0.6	-1.5
Friendships satisfaction	0.5	0.6	2.8	0.7	-0.0	-0.3	0.0	-0.5	-0.1	0.4	1.7	1.1	0.7
Whole body water mass	0.5	2.8	17.4	4.2	1.1	2.0	1.0	-0.4	0.0	1.3	0.6	-0.6	-1.4
Mother’s age at death	0.5	0.7	1.8	0.1	-0.7	-0.4	0.8	-1.3	0.1	-0.8	0.4	-1.2	-1.0
Illnesses of father: High blood pressure	0.5	0.6	1.3	-0.0	-1.2	-1.1	-0.6	0.4	0.1	-1.1	-0.6	0.9	-0.5
Age started oral contraceptive pill	0.5	0.6	1.5	-1.2	0.8	0.0	1.2	-0.2	0.1	0.1	1.0	1.2	-0.6
Ever depressed for a whole week	0.5	0.6	2.7	1.6	-0.3	-0.4	0.9	-0.4	0.1	-0.1	0.1	-0.0	1.3
Neuroticism (Nagel 2018)	0.4	1.0	3.8	-0.7	-0.1	-2.0	0.8	-1.0	1.1	-0.4	0.1	1.4	-0.8
Alzheimer’s Disease (including proxy)	0.4	0.6	2.6	0.4	0.0	0.7	-0.3	-0.2	0.2	0.9	1.3	1.6	-0.5
Blood White Count	0.4	2.7	10.0	-1.8	-1.4	-3.2	-1.0	-1.8	-0.9	-1.0	-0.6	1.0	2.1
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.3	0.6	1.4	0.4	-0.4	0.2	-0.8	1.5	1.3	-0.2	0.4
Severe depression (siblings)	0.4	0.4	1.2	0.2	-0.4	-0.7	1.0	-0.5	1.1	-0.1	0.7	-0.0	0.7
Townsend deprivation index at recruitment	0.4	0.6	1.6	0.5	0.1	1.0	0.2	0.7	0.6	-0.7	-1.1	-1.2	-0.8
Average weekly fortified wine intake	0.4	0.5	1.1	-1.0	-0.6	-0.9	0.6	-1.1	-0.0	-0.5	0.2	0.6	0.6
Age when periods started (menarche)	0.4	1.0	5.6	0.1	-0.7	-0.6	-0.1	-1.0	0.3	-0.6	-1.2	0.3	2.4
Diabetes (self-reported)	0.4	0.7	2.4	0.7	1.1	0.8	0.4	-0.1	0.4	1.0	0.8	-1.6	0.2
Trunk fat-free mass	0.4	2.1	13.2	3.6	0.6	1.4	0.4	-0.2	0.2	1.1	0.4	-0.3	-1.8
Noisy workplace	0.4	0.5	4.2	0.0	0.1	0.2	0.7	-0.1	-0.4	0.0	0.1	2.1	-0.3
Birth weight of first child	0.4	0.7	3.6	0.8	-0.0	-0.4	-1.9	-0.5	-1.2	-0.1	-0.2	0.2	-1.0
Arm fat-free mass (right)	0.4	2.2	10.5	3.2	1.6	2.0	0.9	0.1	0.3	1.6	0.2	0.2	-1.2
Comparative height size at age 10	0.4	2.4	9.5	3.1	-1.1	-1.8	0.9	-0.3	1.6	1.3	1.7	-0.9	-1.0
Overall health rating	0.4	0.8	4.4	-0.1	0.4	1.4	2.1	-0.0	0.2	-0.1	1.0	0.8	-0.0
Family relationship satisfaction	0.4	0.6	2.2	-0.1	-0.6	0.2	-1.2	-0.0	-0.1	-0.8	0.5	1.5	0.8
Illnesses of siblings: Diabetes	0.4	0.5	2.7	0.1	1.0	0.2	0.3	0.4	1.6	0.9	-0.3	0.0	-0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.4	0.0	-0.4	0.8	-0.1	1.6	-0.4	-0.7	-0.3	-0.6	-0.8
Medication for cholesterol	0.4	0.6	2.7	0.2	0.6	0.4	-1.0	0.9	-0.4	0.3	-0.1	1.6	1.0
Medication: Blood pressure	0.4	0.8	4.3	-0.5	-0.5	-0.0	2.1	-1.3	0.9	-0.8	0.3	-0.4	0.3
Basal cell carcinoma (self-reported)	0.4	0.5	1.2	-0.3	0.5	-1.0	-0.1	-0.5	0.5	1.1	-1.0	-0.7	-0.5
Systolic Blood Pressure	0.3	1.5	3.2	1.1	-0.3	-1.8	0.7	-0.2	1.1	1.7	1.2	1.2	1.6
Cardiovascular Disease	0.3	0.9	2.2	0.5	-0.7	-0.5	0.7	-1.4	1.0	-0.1	-0.1	1.4	1.5
Tanning	0.3	3.2	12.5	-0.8	2.8	3.5	-0.3	2.5	0.9	0.6	-1.1	-0.9	-1.1
Medication: Co-codamol	0.3	0.4	2.1	1.4	-0.0	-0.1	0.5	-0.5	-0.3	-0.0	0.5	-0.7	-0.6
High blood pressure	0.3	0.9	2.7	0.3	-0.7	-0.0	1.1	-1.6	1.6	-0.6	-1.1	-0.1	0.5
Medication: Simvastatin	0.3	0.5	1.4	-0.6	-1.0	-1.2	0.5	-0.6	-0.3	-0.4	-0.2	-0.1	-1.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.9	-0.6	-0.2	0.7	-0.8	0.6	-1.4	-1.2	-1.7	-1.3	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	3.8	-0.5	-0.9	-0.4	-0.7	0.2	-0.6	-1.2	-2.0	-1.3	-0.5
Trunk predicted mass	0.3	2.0	13.1	3.6	0.5	1.2	0.3	-0.3	0.2	1.1	0.4	-0.3	-1.8
Standing height	0.3	2.5	5.9	2.4	-2.1	-2.4	-0.2	-2.0	0.7	-0.4	-0.1	-1.8	-1.2
Breastfed as a baby	0.3	0.4	1.3	-0.1	0.1	-0.3	-0.8	0.9	1.2	0.7	-0.9	-0.2	0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.4	-0.6	0.9	0.7	-0.3	1.2	-0.8	0.2	0.2	-1.2	-0.2
Glaucoma (self-reported)	0.3	0.4	1.0	1.0	-0.3	-0.2	-1.0	-0.7	-0.8	-0.5	-0.7	-0.2	-0.1
Medication: Amlodipine	0.3	0.4	1.9	0.5	0.1	0.5	0.5	-0.6	1.4	-0.1	0.3	0.1	1.1
Birth weight	0.3	0.6	2.1	1.5	-0.5	-0.9	-0.9	-1.2	-0.0	0.5	-0.1	0.7	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.1	-0.5	0.0	0.3	0.5	0.2	0.9	-0.3	0.6	0.3	-1.5
Number of full sisters	0.3	0.4	1.6	1.2	0.3	-0.5	-0.2	-0.1	0.2	1.3	0.6	-0.3	0.5
Knee pain experienced in last month	0.3	0.4	1.6	-0.3	0.7	-0.3	1.3	0.6	0.0	0.7	0.2	-0.7	0.9
Hypertension (Self-reported)	0.3	0.9	3.4	0.5	-0.9	-0.0	0.8	-1.9	1.5	-0.8	-1.0	-0.1	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.4	-0.5	0.7	0.8	1.2	0.1	-0.1	-0.1	0.5	0.1	-1.1
Vascular/heart problems diagnosed by doctor	0.3	0.9	4.4	-0.3	1.0	0.6	-0.6	2.1	-1.0	0.6	1.0	-0.0	-0.3
Alzheimer’s Disease (in mother)	0.2	0.3	1.6	0.1	-0.3	0.1	-1.3	-0.2	-0.1	0.4	0.2	0.8	-0.3
Major Depression (MDD)	0.2	0.2	0.6	-0.0	0.6	0.2	0.3	0.0	0.3	0.8	0.4	0.4	-0.8
Blood Red Count	0.2	2.2	8.4	2.1	1.9	2.9	0.1	-1.3	-0.9	0.5	0.9	1.1	0.7
Height	0.2	4.8	10.6	3.3	-2.6	-3.2	-0.1	-2.6	1.2	-0.6	-0.6	-3.1	-1.5
Chronotype (morning person)	0.2	0.6	2.4	-0.6	0.1	-0.8	-0.1	0.3	0.9	-0.4	-1.2	-1.6	0.0
Hand grip strength (left)	0.2	0.7	2.2	1.5	0.3	-0.0	-0.8	-0.2	-0.9	0.7	-1.4	-0.3	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.8	0.6	0.2	0.8	0.3	0.7	-0.1	-0.4	-0.6	-0.6	-1.4
Nervous feelings	0.2	0.4	3.1	0.1	0.3	-0.2	1.8	-0.1	-0.3	0.0	0.0	0.4	-0.6
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.4	0.7	-0.1	0.1	0.6	0.5	-0.1	-0.3	0.1	1.2	0.4
Hair/balding pattern: Pattern 4	0.2	0.4	1.7	0.9	-0.0	-1.0	0.2	-0.2	1.3	0.4	0.3	-0.1	-0.5
Loud music exposure frequency	0.2	0.2	0.7	-0.2	-0.2	0.5	0.2	0.1	0.0	-0.7	0.7	-0.8	0.2
Eye problems/disorders: None of the above	0.2	0.3	1.2	-1.1	0.0	0.4	-0.1	0.3	-0.5	-0.8	0.1	0.1	0.5
Illnesses of father: Heart disease	0.2	0.3	1.7	-0.3	-0.5	-1.3	0.0	-0.0	-0.4	-0.4	0.2	0.1	-0.7
Diabetes diagnosed by doctor	0.2	0.4	1.9	0.3	0.8	0.9	0.1	0.2	-0.0	0.4	0.1	-1.4	0.2
Osteoarthritis (self-reported)	0.2	0.3	1.2	-1.0	0.6	0.3	1.1	-0.0	-0.2	0.5	0.5	0.1	-0.2
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.7	-0.0	0.4	0.2	-0.6	0.3	-0.3	0.2	-0.1	-0.0	0.8
Illnesses of father: None of the above (group 1)	0.1	0.1	0.7	-0.3	-0.5	0.1	-0.6	-0.0	-0.8	-0.0	-0.3	0.1	-0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

TMEM194A

Models

Trait associations