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chr17:73,059,836-74,629,867

Best TWAS P=3.08e-09 · Best GWAS P=1.19e-10 conditioned to 0.00346

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TRIM47	0.15	0.12	enet	13	0.14	2.8e-17	-4.7	5.2	1.7e-07	-0.61	0.86	0.14	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TRIM65	0.21	0.17	lasso	5	0.21	5.2e-25	-5.2	-5.2	1.9e-07	0.66	0.90	0.10	FALSE
3	GTEx	Adipose Subcutaneous	MRPL38	0.08	0.07	lasso	4	0.06	9.3e-06	-5.9	5.9	3.1e-09	-0.77	0.10	0.90	TRUE
4	GTEx	Brain Caudate basal ganglia	FBF1	0.35	0.20	enet	27	0.19	3.3e-06	-4.4	-5.2	1.7e-07	0.61	0.53	0.30	FALSE
5	GTEx	Brain Cerebellar Hemisphere	TRIM47	0.26	0.08	enet	8	0.11	9.3e-04	-4.7	5.2	1.5e-07	-0.61	0.22	0.16	FALSE
6	GTEx	Brain Cerebellar Hemisphere	RP11-552F3.9	0.28	0.16	lasso	5	0.16	7.0e-05	-4.5	5.4	8.7e-08	-0.62	0.16	0.18	FALSE
7	GTEx	Brain Cerebellum	TRIM47	0.30	0.17	lasso	2	0.17	1.1e-05	-5.1	5.1	2.6e-07	-0.59	0.20	0.57	FALSE
8	GTEx	Brain Hypothalamus	TRIM65	0.26	0.09	lasso	7	0.12	9.7e-04	-4.2	-5.9	3.7e-09	0.79	0.03	0.67	FALSE
9	GTEx	Breast Mammary Tissue (Female)	FBF1	0.14	0.13	lasso	3	0.13	1.2e-04	-4.2	-5.3	1.2e-07	0.62	0.04	0.72	FALSE
10	GTEx	Liver	GALK1	0.35	0.16	lasso	9	0.24	2.6e-07	-4.4	-5.8	7.7e-09	0.86	0.01	0.98	FALSE
11	GTEx	Lung	UNC13D	0.12	0.09	enet	15	0.10	3.4e-08	-5.9	-5.2	1.9e-07	0.70	0.08	0.92	FALSE
12	GTEx	Nerve Tibial	TRIM65	0.25	0.10	lasso	6	0.16	8.7e-12	-4.5	-5.3	1.0e-07	0.64	0.91	0.09	FALSE
13	GTEx	Skin Sun Exposed Lower leg	TRIM47	0.09	0.03	lasso	3	0.03	1.5e-03	-5.6	5.5	3.5e-08	-0.71	0.31	0.64	FALSE
14	GTEx	Stomach	FBF1	0.28	0.17	enet	12	0.17	1.5e-08	-4.4	-5.2	2.6e-07	0.74	0.42	0.57	FALSE
15	GTEx	Thyroid	WBP2	0.07	0.06	lasso	2	0.06	4.1e-05	-5.4	-5.9	3.7e-09	0.89	0.03	0.95	FALSE
16	The Cancer Genome Atlas	Glioblastoma Multiforme	GALK1	0.15	0.04	blup	28	0.06	5.9e-03	-5.3	-5.8	6.6e-09	0.81	0.01	0.45	FALSE
17	The Cancer Genome Atlas	Glioblastoma Multiforme	TRIM65	0.08	0.02	enet	7	0.04	1.9e-02	-4.7	-5.5	5.0e-08	0.69	0.02	0.59	FALSE
18	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	FBF1	0.08	0.05	blup	41	0.04	1.1e-02	-4.7	-5.3	1.3e-07	0.68	0.02	0.79	FALSE