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chr19:10,283,932-12,191,233

Best TWAS P=3.29e-13 · Best GWAS P=6.99e-38 conditioned to 5.35e-12

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	ROSMAP	Brain Pre-frontal Cortex	C19orf80	0.08	0.04	enet	17	0.05	3.1e-07	2.6	7.3	3.3e-13	-0.41	0.65	0.33	TRUE
1	GTEx	Adipose Subcutaneous	EPOR	0.11	0.04	lasso	7	0.04	3.8e-04	-7.2	-7.1	1.4e-12	0.48	0.52	0.38	TRUE
5	GTEx	Pancreas	LDLR	0.19	-0.01	enet	5	0.01	9.7e-02	1.3	-6.2	4.2e-10	0.50	0.02	0.71	TRUE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	SPC24	0.06	0.00	enet	15	0.01	1.4e-02	-9.9	7.3	3.7e-13	-0.35	0.00	0.55	FALSE
3	GTEx	Esophagus Mucosa	SMARCA4	0.18	0.03	enet	15	0.09	8.2e-07	-4.5	6.0	2.3e-09	-0.36	0.95	0.00	FALSE
8	YFS	Blood	SMARCA4	0.02	0.01	enet	3	0.00	9.2e-03	-4.3	5.9	3.0e-09	-0.39	0.15	0.07	FALSE
6	NTR	Blood	SMARCA4	0.07	0.06	lasso	11	0.06	9.0e-18	-5.8	5.8	7.6e-09	-0.38	1.00	0.00	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	C19orf52	0.05	0.06	lasso	4	0.06	2.5e-06	-4.9	5.5	4.2e-08	-0.36	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C19orf52	0.04	0.04	blup	27	0.03	1.7e-04	-5.5	5.3	8.8e-08	-0.37	0.00	1.00	FALSE
2	GTEx	Cells Transformed fibroblasts	CARM1	0.11	0.01	lasso	4	0.00	6.9e-01	-5.0	-5.3	1.4e-07	0.35	0.29	0.04	FALSE
4	GTEx	Esophagus Muscularis	SMARCA4	0.16	0.00	lasso	6	0.03	7.2e-03	-7.3	5.2	1.8e-07	-0.39	0.17	0.08	FALSE