[Hub]/) : Traits : Medication: Allopurinol : ← →

chr11:63,305,184-66,262,606

Best TWAS P=5.58e-18 · Best GWAS P=2.38e-15 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NRXN2 0.11 0.05 enet 21 0.05 3.4e-05 6.1 6.0 1.6e-09 0.75 0.52 0.47 TRUE
2 GTEx Artery Tibial NRXN2 0.17 0.12 lasso 5 0.12 6.9e-10 6.1 5.9 3.3e-09 0.80 0.82 0.18 FALSE
3 GTEx Cells Transformed fibroblasts NRXN2 0.15 0.05 lasso 4 0.06 2.0e-05 6.1 6.5 7.0e-11 0.84 0.09 0.90 TRUE
4 GTEx Muscle Skeletal VEGFB 0.19 0.00 enet 31 0.04 1.7e-04 7.3 -5.4 5.2e-08 -0.56 0.07 0.32 TRUE
5 GTEx Nerve Tibial NRXN2 0.08 0.05 lasso 4 0.07 2.0e-05 5.9 5.7 1.4e-08 0.76 0.60 0.30 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic NRXN2 0.10 0.07 enet 6 0.05 7.8e-04 6.1 6.1 8.2e-10 0.74 0.44 0.44 FALSE
7 GTEx Skin Sun Exposed Lower leg NRXN2 0.11 0.05 enet 27 0.08 7.0e-07 6.1 5.9 2.9e-09 0.73 0.44 0.56 FALSE
8 GTEx Spleen NRXN2 0.46 0.12 lasso 5 0.10 1.3e-03 6.1 5.9 3.0e-09 0.74 0.32 0.08 FALSE
9 ROSMAP Brain Pre-frontal Cortex OVOL1 0.16 0.24 lasso 2 0.24 1.3e-30 5.2 5.2 1.5e-07 0.08 0.00 1.00 TRUE
10 The Cancer Genome Atlas Breast Invasive Carcinoma NRXN2 0.01 0.02 lasso 3 0.01 5.1e-04 6.0 6.0 1.6e-09 0.75 0.09 0.31 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC22A12 0.02 0.02 blup 38 0.02 4.3e-03 7.8 8.6 5.6e-18 0.93 0.01 0.88 TRUE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SLC22A12 0.05 0.02 blup 38 0.03 6.3e-03 5.6 8.0 1.2e-15 0.92 0.01 0.64 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SLC22A11 0.06 0.03 blup 42 0.04 1.2e-03 7.2 -8.2 2.5e-16 -0.72 0.06 0.52 TRUE
14 The Cancer Genome Atlas Prostate Adenocarcinoma SLC22A11 0.05 0.03 lasso 5 0.02 2.8e-03 7.3 -7.5 6.3e-14 -0.37 0.06 0.14 TRUE