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chr11:63,305,184-66,262,606

Best TWAS P=5.58e-18 · Best GWAS P=2.38e-15 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC22A12	0.02	0.02	blup	38	0.02	4.3e-03	7.8	8.6	5.6e-18	0.93	0.01	0.88	TRUE
13	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC22A11	0.06	0.03	blup	42	0.04	1.2e-03	7.2	-8.2	2.5e-16	-0.72	0.06	0.52	TRUE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC22A11	0.05	0.03	lasso	5	0.02	2.8e-03	7.3	-7.5	6.3e-14	-0.37	0.06	0.14	TRUE
3	GTEx	Cells Transformed fibroblasts	NRXN2	0.15	0.05	lasso	4	0.06	2.0e-05	6.1	6.5	7.0e-11	0.84	0.09	0.90	TRUE
1	GTEx	Adipose Subcutaneous	NRXN2	0.11	0.05	enet	21	0.05	3.4e-05	6.1	6.0	1.6e-09	0.75	0.52	0.47	TRUE
4	GTEx	Muscle Skeletal	VEGFB	0.19	0.00	enet	31	0.04	1.7e-04	7.3	-5.4	5.2e-08	-0.56	0.07	0.32	TRUE
9	ROSMAP	Brain Pre-frontal Cortex	OVOL1	0.16	0.24	lasso	2	0.24	1.3e-30	5.2	5.2	1.5e-07	0.08	0.00	1.00	TRUE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC22A12	0.05	0.02	blup	38	0.03	6.3e-03	5.6	8.0	1.2e-15	0.92	0.01	0.64	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	NRXN2	0.10	0.07	enet	6	0.05	7.8e-04	6.1	6.1	8.2e-10	0.74	0.44	0.44	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	NRXN2	0.01	0.02	lasso	3	0.01	5.1e-04	6.0	6.0	1.6e-09	0.75	0.09	0.31	FALSE
7	GTEx	Skin Sun Exposed Lower leg	NRXN2	0.11	0.05	enet	27	0.08	7.0e-07	6.1	5.9	2.9e-09	0.73	0.44	0.56	FALSE
8	GTEx	Spleen	NRXN2	0.46	0.12	lasso	5	0.10	1.3e-03	6.1	5.9	3.0e-09	0.74	0.32	0.08	FALSE
2	GTEx	Artery Tibial	NRXN2	0.17	0.12	lasso	5	0.12	6.9e-10	6.1	5.9	3.3e-09	0.80	0.82	0.18	FALSE
5	GTEx	Nerve Tibial	NRXN2	0.08	0.05	lasso	4	0.07	2.0e-05	5.9	5.7	1.4e-08	0.76	0.60	0.30	FALSE