TWAS hub - OVOL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.1595	0.0342	0.00000	0.243	0.193	0.225	0.234	0.241	6.3e-31	2.9e-24	1.9e-28	1.1e-29	1.3e-30
2	TCGA	Head and Neck Squamous Cell Carcinoma	0.0746	0.0327	0.00028	0.000	0.042	0.038	NA	0.013	3.0e-01	1.6e-05	3.9e-05	NA	1.1e-02
3	TCGA	Brain Lower Grade Glioma	0.0334	0.0181	0.00090	0.034	0.024	0.024	NA	0.022	9.4e-05	8.3e-04	8.9e-04	NA	1.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Allergy or Eczema	15.9	41.7	69.8	6.7	-3.2	8.4
Hayfever, allergic rhinitis or eczema	14.8	32.1	51.4	5.8	-3.3	7.2
Gout (self-reported)	13.7	18.8	34.1	5.8	-0.7	4.7
Blood Eosinophil Count	12.1	93.1	161.3	10.5	-2.8	12.7
Medication: Allopurinol	11.9	15.8	27.5	5.2	-1.3	4.3
Allergy	11.6	26.7	41.9	-5.2	3.3	-6.5
Heel T-Score	8.4	67.0	118.8	10.9	-1.7	8.9
Number of treatments/medications taken	7.5	13.4	19.2	4.4	-3.3	3.2
Medication: Blood pressure	6.8	12.9	25.9	5.1	0.0	3.6
Asthma (self-reported)	6.6	13.1	17.0	3.1	-3.6	4.1
LDL Cholesterol	6.5	10.2	14.2	-3.7	1.7	-3.8
Medication: Amlodipine	6.4	8.9	16.6	4.1	-1.3	2.9
Heel bone mineral density (BMD) T-score, automated (left)	6.0	13.7	24.4	4.9	-1.4	3.8
Comparative body size at age 10	5.5	15.3	23.7	-4.4	-1.6	-4.9
Heel bone mineral density (BMD) T-score, automated (right)	5.4	12.3	22.6	4.8	-0.6	3.7
Asthma	5.4	10.6	14.2	2.8	-3.1	3.8
Medication: Ventolin 100micrograms inhaler	5.2	6.7	9.1	2.0	-2.6	3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	5.2	6.1	8.5	-2.9	1.7	-2.6
Breast Cancer	5.0	12.0	27.8	2.1	-2.0	5.3
Commuting to job workplace: Cycle	5.0	6.1	7.8	-2.8	1.8	-2.7
Hayfever/allergic rhinitis (self-reported)	4.9	6.5	12.4	2.7	0.4	3.5
Prostate Cancer	4.6	6.4	10.2	-2.9	0.8	-3.2
Medication: Seretide 50 evohaler	4.5	5.2	5.7	2.1	-2.4	2.3
Medication: Paracetamol	4.3	7.2	8.3	2.9	-2.7	2.4
Medication: Lisinopril	4.3	5.5	10.4	3.2	-1.3	2.1
Blood Platelet Count	4.2	49.0	60.4	5.2	-7.7	7.8
Relative age of first facial hair	4.2	8.7	13.7	-3.7	-2.0	-2.9
Exposure to tobacco smoke outside home	3.9	5.2	7.5	2.7	-1.7	2.2
Mouth/teeth dental problems: Loose teeth	3.9	4.7	7.0	-2.3	2.7	-1.4
Eye problems/disorders: Glaucoma	3.8	4.5	8.8	2.1	0.4	3.0
Age started oral contraceptive pill	3.7	4.6	8.2	-2.9	1.7	-1.7
Medication for cholesterol	3.6	5.4	10.2	-3.2	0.3	-2.4
Medication: Atenolol	3.5	4.3	8.2	2.9	0.2	2.2
Number of self-reported non-cancer illnesses	3.5	6.0	10.8	3.3	-0.7	2.6
Glaucoma (self-reported)	3.4	4.0	9.0	1.7	0.5	3.0
Medication: Blood pressure	3.4	6.0	12.6	3.5	-1.3	1.9
Hypertension (Self-reported)	3.4	9.3	22.9	4.8	-0.4	2.2
Average weekly red wine intake	3.4	5.0	10.8	-2.0	3.3	-0.6
Medication: Atorvastatin	3.4	4.2	6.6	2.6	0.6	2.4
Respiratory disease	3.3	7.3	11.5	2.9	-1.5	3.4
Loud music exposure frequency	3.3	3.6	4.8	2.2	-1.5	1.9
Stomach or abdominal pain in last month	3.2	4.0	6.4	2.0	-2.5	1.2
Pulse rate	3.2	5.4	10.8	1.2	-3.3	2.0
Mouth/teeth dental problems: Bleeding gums	3.2	4.2	5.1	-2.2	1.7	-2.2
Medication: Paracetamol	3.2	5.0	6.9	2.3	-2.6	1.7
Lung cancer (father)	3.0	3.6	6.4	-2.0	0.5	-2.5
Medication for pain relief, constipation, heartburn	3.0	5.1	6.9	-2.6	2.2	-1.9
Medication: Aspirin	2.9	3.8	6.3	2.5	-1.0	2.0
Number of incorrect matches in round	2.8	4.7	11.2	1.5	-3.3	0.8
Maternal smoking around birth	2.7	4.0	6.4	2.5	-1.8	1.5
Depression (self-reported)	2.7	3.3	4.5	1.9	-1.2	2.1
Mean time to correctly identify matches	2.7	5.2	7.3	-2.7	1.7	-2.3
Mineral and other dietary supplements	2.6	3.4	5.6	-2.1	0.5	-2.4
Lupus	2.5	3.8	7.6	-0.8	2.8	-1.8
Ever used hormone-replacement therapy (HRT)	2.5	3.2	4.0	1.6	-2.0	1.7
Waist Hip Ratio (WHR)	2.4	10.9	18.8	2.9	4.3	2.3
Taking other prescription medications	2.4	3.8	4.9	2.2	-1.8	1.8
Had menopause	2.4	3.0	4.8	1.4	-1.6	2.2
Headache pain in last month	2.4	4.1	6.0	1.7	-1.9	2.4
Hypothyroidism/myxoedema (self-reported)	2.4	4.6	6.7	2.5	-0.9	2.6
Guilty feelings	2.4	3.6	5.6	2.4	-0.6	2.2
Basal cell carcinoma (self-reported)	2.4	2.8	5.2	-2.3	0.6	-1.7
Hypothyroidism (self reported)	2.3	5.3	8.3	2.7	-0.8	2.9
High blood pressure	2.3	6.4	16.6	4.1	-0.0	1.6
Illnesses of father: None of the above (group 1)	2.3	2.8	4.3	-1.9	0.8	-2.1
Supplements: Fish oil (including cod liver oil)	2.3	3.0	4.4	1.7	-1.2	2.1
Relative age voice broke	2.2	3.3	5.7	-2.4	0.4	-2.0
Impedance of arm (left)	2.2	10.0	21.3	2.7	1.3	4.6
Illnesses of siblings: Diabetes	2.2	2.8	4.6	2.1	-0.2	1.9
Vascular/heart problems diagnosed by doctor	2.2	5.9	15.1	-3.9	-0.7	-1.5
Alzheimer’s Disease (in mother)	2.1	2.4	4.4	1.7	-0.0	2.1
Impedance of leg (right)	2.1	10.2	21.0	1.1	4.6	2.9
Illnesses of siblings	2.1	3.0	4.4	-2.1	1.4	-1.6
Birth weight	2.1	4.6	8.6	-1.0	-2.9	-2.0
Eye problems/disorders: None of the above	2.1	2.4	4.4	-1.7	0.0	-2.1
Diastolic blood pressure, automated reading	2.1	6.6	14.8	3.9	1.6	1.6
Impedance of leg (left)	2.0	9.9	17.0	1.4	4.1	3.2
Number of full sisters	2.0	2.4	3.4	1.8	-1.0	1.7
Chest pain or discomfort	2.0	2.8	5.0	2.2	0.3	1.9
Alzheimer’s Disease (including proxy)	1.9	2.7	5.1	1.5	0.9	2.3
Systolic Blood Pressure	1.9	9.6	19.4	4.4	2.6	1.6
Impedance of arm (right)	1.9	9.0	19.4	2.2	1.6	4.4
Back pain experienced in last month	1.9	2.7	4.6	2.2	-1.2	1.4
Breast cancer (self-reported)	1.9	2.2	5.7	-0.7	0.7	-2.4
Reaction Time	1.8	3.4	4.5	-2.1	1.4	-2.0
Ovarian Cancer	1.8	2.4	2.9	1.7	-1.5	1.4
Mean Putamen Volume	1.8	2.0	4.6	-1.2	-0.1	-2.1
Mother’s age at death	1.8	2.2	4.4	-2.1	0.7	-1.4
Impedance of whole body	1.8	9.0	14.6	1.6	3.1	3.8
Alzheimer’s Disease (in father)	1.7	1.8	2.5	1.6	0.6	1.6
Coronary Artery Disease (CAD)	1.7	2.0	4.4	2.1	0.0	1.3
Cardiovascular Disease	1.7	5.6	15.6	4.0	0.2	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	2.9	1.5	-1.7	1.2
Myopia	1.7	2.5	3.2	-1.8	1.7	-1.2
Depression (Nagel 2018)	1.6	2.5	3.7	1.9	-1.7	1.0
Schizophrenia vs Biploar Disorder	1.6	2.1	2.9	-1.1	1.7	-1.5
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.6	-0.8	1.1	-1.9
BMI	1.6	9.3	19.8	-0.0	-4.5	-2.9
Falls in the last year	1.6	2.2	2.7	1.6	-1.4	1.3
Tense / ‘highly strung’	1.6	2.7	3.6	1.5	-1.9	1.5
Pulse wave reflection index	1.6	2.0	4.0	-0.8	2.0	-1.2
Major Depression (MDD)	1.5	1.8	2.9	1.7	-0.9	1.3
Supplements: Zinc	1.5	1.6	2.3	-1.5	0.9	-1.3
Average weekly fortified wine intake	1.5	1.7	4.5	-0.8	-2.1	-0.3
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	2.6	-1.2	0.8	-1.6
Alcohol intake versus 10 years previously	1.5	2.2	5.7	2.4	0.1	1.0
Medication: Aspirin	1.5	1.9	3.5	1.9	-0.4	1.4
Illnesses of father: Heart disease	1.5	2.1	3.7	1.5	0.6	1.9
Average weekly champagne plus white wine intake	1.5	2.1	4.7	0.6	-1.1	2.2
Irritability	1.5	2.6	3.2	1.7	-1.3	1.8
Ever had prostate specific antigen (PSA) test	1.5	1.7	3.2	-1.4	-0.1	-1.8
Schizophrenia (2018)	1.4	3.0	3.8	-1.4	2.0	-1.8
Vitamin and mineral supplements	1.4	1.9	3.1	-1.6	-0.3	-1.8
Chronic bronchitis/emphysema (father)	1.4	1.6	4.7	-0.3	-2.2	-0.0
High blood pressure (mother)	1.4	1.9	4.4	2.1	-0.6	1.0
Illnesses of father: High blood pressure	1.4	1.7	2.4	1.1	-1.2	1.6
Ever depressed for a whole week	1.4	1.8	3.4	-1.9	0.2	-1.4
Multivitamins +/- minerals	1.3	1.7	2.4	1.3	1.0	1.5
Body mass index (BMI)	1.3	5.4	9.0	0.1	-3.0	-2.7
Qualifications: College or University degree	1.3	4.1	9.0	-1.8	3.0	-0.1
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	2.7	-1.0	-1.1	-1.6
Osteoarthritis (self-reported)	1.3	1.6	3.8	1.9	0.0	1.1
Medication: Co-codamol	1.2	1.4	3.5	-0.6	-0.5	-1.9
Diabetes (father)	1.2	1.4	3.7	0.3	1.9	-0.7
Supplements: Glucosamine	1.2	1.6	2.1	1.5	0.9	1.3
Heart attack	1.2	1.6	3.9	0.8	2.0	0.4
Pain all over the body in last month	1.2	1.3	2.7	-0.4	1.0	-1.7
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	4.6	2.1	-0.3	1.1
Hair/balding pattern: Pattern 3	1.2	1.8	2.5	-1.6	1.5	-0.7
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	5.3	-2.3	0.4	-0.8
Unable to work because of sickness or disability	1.2	1.5	2.4	-0.8	1.6	-1.2
Average weekly spirits intake	1.1	1.4	2.7	-1.0	-0.6	-1.6
Medication: Metformin	1.1	1.6	1.8	-1.1	1.3	-1.3
Mouth/teeth dental problems	1.1	1.6	3.1	0.9	-1.0	1.8
Number of live births	1.1	1.6	2.7	0.9	-1.1	1.6
Noisy workplace	1.1	1.4	2.9	1.1	-1.7	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	4.6	0.5	-2.1	0.3
Eye problems/disorders: Cataract	1.1	1.2	2.4	1.1	-0.1	1.5
Medication: Bendroflumethiazide	1.1	1.6	3.8	1.9	-0.8	0.7
Alcohol drinker status: Never	1.1	1.4	2.2	-1.1	-1.5	-0.8
Bipolar Disorder (2011)	1.0	0.9	1.8	1.4	-0.7	0.7
Ulcerative Colitis	1.0	1.4	3.6	0.9	-1.9	-0.0
Systolic blood pressure, automated reading	1.0	2.9	5.2	2.3	1.8	0.4
Medication: Levothyroxine sodium	1.0	1.7	3.2	1.4	-0.3	1.8
Illnesses of mother	1.0	1.3	2.6	-1.6	0.1	-1.1
Number of full brothers	1.0	1.2	3.6	-0.1	1.9	-0.2
Medication: Ibuprofen	1.0	1.2	3.0	0.8	-1.7	0.0
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.2	-1.5	0.3	-1.2
Ever had bowel cancer screening	1.0	1.2	2.0	-1.2	-0.4	-1.4
Hearing aid user	1.0	1.1	3.0	0.5	-1.7	0.4
Heart attack/myocardial infarction (self-reported)	1.0	1.3	2.8	1.0	1.7	0.5
Crohns Disease (2017)	0.9	2.1	4.8	-0.3	-1.1	-2.2
Rheumatoid Arthritis	0.9	1.2	3.1	1.8	-0.1	0.8
Schizophrenia (2014)	0.9	2.0	3.1	-1.0	1.3	-1.8
Blood White Count	0.9	6.7	9.5	2.9	-1.4	3.1
Townsend deprivation index at recruitment	0.9	1.2	2.8	1.7	0.6	0.7
Hip circumference	0.9	4.0	8.0	1.7	-2.8	-1.0
Forced vital capacity (FVC), Best measure	0.9	3.3	7.4	1.0	2.7	1.2
Wheeze or whistling in the chest in last year	0.9	1.5	1.9	1.4	-0.9	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.2	-1.5	-0.2	-1.0
Migraine (self-reported)	0.9	1.1	2.6	-1.6	0.4	-0.7
Heart disease (mother)	0.9	1.1	1.6	1.2	0.5	1.3
Pulse rate, automated reading	0.9	2.9	5.5	1.1	-2.3	1.4
Medication: Gliclazide	0.9	1.1	2.7	0.7	-1.6	0.1
Ever taken oral contraceptive pill	0.9	1.0	2.8	-0.3	1.7	0.5
Heart disease (siblings)	0.9	1.1	2.2	0.9	-1.5	0.7
Irritable Bowel Disease (IBD)	0.8	1.8	3.5	-0.2	-1.4	-1.9
HDL Cholesterol	0.8	1.4	3.0	-0.4	-1.7	1.0
Medication for hormone replacement therapy	0.8	0.9	1.8	0.4	-1.3	0.9
Age when periods started (menarche)	0.8	2.0	3.8	0.3	-1.4	2.0
Forced vital capacity (FVC)	0.8	3.0	5.1	1.5	2.3	1.4
Medication: Cholesterol lowering	0.8	1.2	3.1	1.7	0.6	0.6
Suffer from ‘nerves’	0.8	1.2	2.5	-0.9	1.6	-0.5
Arm fat percentage (left)	0.8	3.1	6.9	1.0	-2.6	-1.1
Wears glasses or contact lenses	0.8	1.0	1.5	-1.0	-1.2	-0.6
Depressed Affect (Nagel 2018)	0.7	1.6	2.7	1.6	0.1	1.4
Body Mass Index (BMI) (2010)	0.7	0.9	1.3	-0.8	1.0	-1.1
Neuroticism (2016)	0.7	1.1	2.2	1.5	0.5	0.9
Primary Biliary Cirrhosis	0.7	1.1	1.7	1.3	-1.2	0.2
Triglycerides	0.7	1.2	1.5	1.2	1.0	1.0
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	1.2	1.1	-0.3	1.0
Angina	0.7	1.0	1.2	1.1	1.1	0.8
Had other major operations	0.7	0.9	1.3	1.1	0.7	1.0
Arm fat percentage (right)	0.7	2.7	5.8	0.7	-2.4	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.1	0.8	-1.4	0.1
Pulse wave Arterial Stiffness index	0.7	0.8	1.5	1.2	-0.4	0.8
Arm fat mass (right)	0.7	2.7	4.5	0.8	-2.1	-1.7
Standing height	0.7	7.0	8.5	2.8	2.9	2.2
Shortness of breath walking on level ground	0.7	0.8	1.9	-1.4	-0.1	-0.7
Emphysema/chronic bronchitis	0.7	0.8	1.7	-0.8	1.3	-0.5
Leg fat mass (right)	0.7	2.5	6.2	-0.0	-1.2	-2.5
Alcohol intake frequency.	0.7	1.6	4.2	2.1	-0.7	0.3
Overall health rating	0.7	1.5	2.4	1.2	-1.6	-0.9
Age at last live birth	0.7	1.0	2.1	-0.5	1.5	0.7
Arm fat mass (left)	0.7	3.1	5.8	1.0	-2.4	-1.6
Miserableness	0.7	1.1	2.0	0.5	1.4	1.1
Commuting to job workplace: Public transport	0.7	0.8	2.3	-0.3	1.5	0.2
Neuroticism (Nagel 2018)	0.6	1.5	2.0	1.4	-0.8	1.4
Crohns Disease (2012)	0.6	0.9	2.0	-0.2	-0.8	-1.4
Height	0.6	12.2	16.1	4.0	3.3	3.1
Lung FEV1/FVC ratio	0.6	3.0	4.6	-2.1	-0.0	-2.1
Neuroticism	0.6	1.5	2.0	1.3	-0.8	1.4
Sensitivity / hurt feelings	0.6	0.9	1.0	1.0	-0.9	1.0
Severe depression (siblings)	0.6	0.7	1.6	0.5	-1.2	0.5
Pack years adult smoking proportion	0.6	0.8	1.6	-0.7	1.2	-0.7
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.8	0.4	-1.4	0.1
Medication: Ramipril	0.6	0.8	2.3	1.5	0.1	0.2
Prospective memory result	0.6	0.7	1.9	0.5	-1.4	0.0
Peak expiratory flow (PEF)	0.6	1.4	3.2	0.9	1.8	0.5
High blood pressure (siblings)	0.6	0.9	2.1	1.4	-0.7	0.5
Pulse wave peak to peak time	0.6	0.8	1.3	-1.2	0.7	-0.7
Leg pain on walking	0.6	0.8	1.5	-0.0	1.2	-0.9
Leg fat-free mass (right)	0.6	3.2	6.6	1.2	-2.6	-1.2
Loneliness, isolation	0.6	0.9	2.3	-0.5	1.5	0.1
Long-standing illness, disability or infirmity	0.6	0.9	2.3	1.5	-0.6	-0.0
Leg predicted mass (right)	0.6	3.2	6.8	1.2	-2.6	-1.2
Pack years of smoking	0.6	0.9	1.9	-0.6	1.4	-0.6
Leg fat mass (left)	0.6	2.4	4.7	0.4	-1.6	-2.2
Ulcerative Colitis (UC)	0.5	0.9	2.2	0.4	-1.5	-0.7
Hair Pigment	0.5	15.5	23.5	-4.8	-2.7	-4.0
Leg fat-free mass (left)	0.5	2.7	5.1	1.0	-2.3	-1.5
Trunk fat percentage	0.5	1.8	2.8	1.7	-1.6	-0.5
Leg predicted mass (left)	0.5	2.8	5.4	1.0	-2.3	-1.5
Weight	0.5	2.2	2.6	1.3	-1.6	-1.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	4.6	0.6	2.1	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	4.6	0.0	2.1	0.5
Length of working week for main job	0.5	0.6	1.2	-0.7	0.3	-1.1
Birth weight of first child	0.5	0.9	1.7	-0.7	-1.3	-0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	1.4	0.1	-1.2	0.9
Angina (self-reported)	0.5	0.7	1.1	0.8	1.0	0.5
Medication: Omeprazole	0.5	0.6	0.8	-0.6	0.7	-0.9
Comparative height size at age 10	0.5	2.8	4.3	2.1	1.8	0.9
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.7	-0.1	-1.3	-0.1
Mood swings	0.5	0.8	1.4	1.2	-0.3	1.0
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.3	0.0	1.5	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	0.7	0.8	-0.8	0.9
Risk taking	0.5	0.7	1.9	0.2	1.4	0.4
Bipolar Disorder (2018)	0.4	0.7	2.0	0.2	-1.4	0.1
Bipolar Disorder or Schizophrenia	0.4	1.0	1.8	-0.9	0.6	-1.3
Age at First Birth	0.4	0.6	1.4	-0.7	1.2	0.3
Blood Red Count	0.4	4.0	7.6	-0.5	2.8	-2.1
Smoking Status	0.4	1.1	3.0	1.7	-0.4	0.3
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.0	0.6	1.4	-0.3
Lung FVC	0.4	2.2	4.4	1.3	2.1	0.8
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.0	0.8	-1.0	0.2
Hearing difficulty/problems: Yes	0.4	0.6	1.1	0.6	-1.1	0.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.4	1.2	0.0	0.4
Ever had hysterectomy (womb removed)	0.4	0.5	1.2	-0.4	-0.4	-1.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	0.7	-0.4	0.9	-0.8
Trunk fat mass	0.4	1.7	2.0	1.4	-1.4	-1.1
Waist circumference	0.4	1.6	4.1	2.0	-0.5	-0.7
Alcohol usually taken with meals	0.4	0.7	1.1	-0.2	0.9	1.1
Financial difficulties in last 2 years	0.4	0.5	0.9	0.8	0.1	1.0
Father’s age at death	0.4	0.5	1.1	-1.1	-0.6	-0.4
Worrier / anxious feelings	0.4	0.7	2.0	-0.1	-1.4	0.2
Happiness	0.4	0.5	1.1	1.1	0.1	0.7
Medication: Lansoprazole	0.4	0.4	0.6	-0.8	0.1	-0.8
Hair/balding pattern: Pattern 4	0.4	1.0	1.6	0.1	1.3	1.1
Body fat percentage	0.4	1.5	2.2	1.1	-1.5	-1.1
Leg fat percentage (right)	0.4	1.4	4.0	-0.0	-0.5	-2.0
Whole body fat mass	0.4	1.9	2.5	1.1	-1.4	-1.6
Arm predicted mass (right)	0.4	1.8	4.3	0.5	-0.9	-2.1
Smoking status: Previous	0.4	0.6	1.9	1.4	-0.2	0.0
Qualifications: nursing, teaching	0.4	0.6	1.7	0.1	0.3	1.3
High cholesterol (Self-reported)	0.4	0.7	1.6	-0.4	0.5	-1.2
Fasting Glucose	0.3	0.4	0.6	0.4	0.7	0.8
Fed-up feelings	0.3	0.6	1.4	0.2	1.2	-0.4
Serious illness, injury or assault to yourself	0.3	0.4	0.8	0.4	0.9	-0.4
Sitting height	0.3	2.2	6.2	0.3	2.5	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.3	0.1	-1.2	0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	0.7	-0.5	-0.3	-0.8
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.1	-0.2	-1.0	-0.3
Arm fat-free mass (right)	0.3	1.7	4.6	0.4	-0.5	-2.1
Family relationship satisfaction	0.3	0.4	0.6	-0.8	0.4	-0.6
Knee pain experienced in last month	0.3	0.4	1.3	-0.0	-0.1	-1.1
Whole body fat-free mass	0.3	1.7	2.2	0.9	-1.4	-1.5
Commuting to job workplace: Walk	0.3	0.4	1.0	0.3	0.2	1.0
Osteoporosis (self-reported)	0.3	0.4	0.5	-0.7	0.5	-0.6
Whole body water mass	0.3	1.6	2.6	0.7	-1.3	-1.6
Ever smoked	0.3	0.4	1.0	1.0	0.1	0.6
Basal metabolic rate	0.3	1.9	2.4	1.0	-1.5	-1.6
Leg fat percentage (left)	0.3	1.3	2.4	0.4	-1.1	-1.5
Arm fat-free mass (left)	0.3	1.7	3.6	0.5	-1.1	-1.9
Alcohol drinker status: Previous	0.3	0.4	0.6	-0.1	0.8	-0.7
Arm predicted mass (left)	0.3	1.6	4.1	0.4	-0.8	-2.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.2	-1.1	0.7	0.3
Chronotype (morning person)	0.2	0.5	1.3	0.2	-0.5	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.7	0.8	-0.2	-0.3
Past tobacco smoking	0.2	0.4	1.3	-1.1	-0.0	0.1
Hair/balding pattern: Pattern 2	0.2	0.2	0.3	-0.6	-0.5	-0.3
Qualifications: None of the above	0.2	0.5	0.9	0.9	0.8	-0.3
Diabetes (self-reported)	0.2	0.3	0.7	-0.1	0.8	-0.2
Medication: Simvastatin	0.2	0.3	0.8	0.9	-0.2	-0.3
Fluid intelligence score	0.2	0.4	1.0	0.3	0.0	1.0
Neuroticism score	0.2	0.4	0.7	0.7	-0.3	0.8
Trunk fat-free mass	0.2	0.9	2.0	0.7	-0.6	-1.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.5	-0.5	0.7	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	0.4	-0.4	0.6
Mouth/teeth dental problems: Dentures	0.2	0.4	0.8	0.5	-0.3	-0.9
Trunk predicted mass	0.2	0.9	1.7	0.8	-0.7	-1.3
Exposure to tobacco smoke at home	0.2	0.2	0.3	-0.5	0.3	-0.6
Breastfed as a baby	0.2	0.3	0.5	-0.6	0.7	0.2
Blood clot in the leg (DVT)	0.2	0.2	0.6	-0.3	0.2	-0.8
Worry too long after embarrassment	0.2	0.3	0.8	-0.9	0.0	-0.4
Health satisfaction	0.2	0.3	0.7	0.1	-0.5	-0.8
Neck or shoulder pain in last month	0.2	0.3	0.6	0.4	-0.4	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	0.3	0.7	0.1
Had major operations	0.2	0.3	0.8	0.9	-0.2	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	0.7	0.6	0.8	0.7
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.5	-0.7	0.1	-0.6
Diabetes diagnosed by doctor	0.2	0.3	0.6	0.4	0.8	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.1	0.2	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.8	-0.4	-0.0	-0.9
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.5	0.1	-0.7	0.0
Average weekly beer plus cider intake	0.2	0.3	0.5	0.4	0.7	-0.3
Pain experienced in last month	0.2	0.3	0.5	-0.3	0.7	0.4
Worry (Nagel 2018)	0.1	0.1	0.3	-0.2	-0.5	-0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.5	-0.7	0.4	-0.3
HbA1C	0.1	0.2	0.3	0.2	-0.4	0.5
Tanning	0.1	1.8	3.8	-0.6	-1.9	1.1
Hand grip strength (left)	0.1	0.3	0.7	-0.3	0.8	-0.2
Diabetes (mother)	0.1	0.2	0.5	0.7	-0.2	0.1
Hand grip strength (right)	0.1	0.2	0.3	0.5	0.4	0.5
Current tobacco smoking	0.1	0.1	0.2	0.1	-0.4	-0.4
Qualifications: CSEs or equivalent	0.1	0.1	0.2	0.4	-0.4	-0.1
Nervous feelings	0.1	0.3	0.5	0.1	-0.6	0.7
Hearing difficulty/problems with background noise	0.1	0.2	0.2	0.4	0.5	0.4
Time employed in main current job	0.1	0.1	0.3	-0.4	0.6	0.0
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.1	-0.4	-0.4
Number of children fathered	0.1	0.1	0.3	0.1	-0.2	-0.6
Age at first live birth	0.1	0.2	0.3	-0.6	0.5	0.2
Friendships satisfaction	0.1	0.1	0.1	-0.4	-0.2	0.2
Smoking status: Current	0.1	0.1	0.2	-0.1	-0.2	-0.5
Financial situation satisfaction	0.1	0.2	0.4	0.0	0.7	-0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.4	0.6	0.2	0.2
Fractured/broken bones in last 5 years	0.1	0.1	0.3	0.2	0.5	0.2
Supplements: Calcium	0.1	0.1	0.2	-0.1	0.4	0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.4	-0.3	0.2	-0.6
Supplements: Vitamin C	0.0	0.1	0.1	0.1	-0.3	0.3
Number of operations (self-reported)	0.0	0.0	0.1	0.3	0.0	-0.2
Cholesterol lowering medication	0.0	0.0	0.1	0.3	0.0	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	0.0	0.2	-0.3

Hub : Genes

OVOL1

Models

Trait associations