[Hub]/) : Traits : Medication: Atorvastatin : →

chr1:108,854,166-110,733,794

Best TWAS P=3.78e-29 · Best GWAS P=6.62e-29 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CELSR2	0.03	0.00	lasso	10	0.01	1.5e-02	-8.27	7.2	5.1e-13	-0.58	0.10	0.33	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PSRC1	0.20	0.04	lasso	8	0.13	4.8e-16	2.66	-6.9	5.1e-12	0.63	0.01	0.99	FALSE
3	GTEx	Cells Transformed fibroblasts	GPSM2	0.12	0.00	enet	24	0.01	5.6e-02	-0.38	5.3	1.4e-07	-0.39	0.05	0.43	FALSE
4	GTEx	Esophagus Mucosa	PSRC1	0.18	0.14	lasso	3	0.14	2.4e-09	-10.94	-11.0	5.5e-28	0.97	0.01	0.99	FALSE
5	GTEx	Liver	CELSR2	0.39	0.36	lasso	1	0.35	1.0e-10	-10.94	-10.9	7.1e-28	1.00	0.01	0.99	FALSE
6	GTEx	Liver	ATXN7L2	0.39	0.04	lasso	12	0.21	1.3e-06	-2.23	-7.6	3.7e-14	0.69	0.09	0.74	FALSE
7	GTEx	Muscle Skeletal	CELSR2	0.41	0.31	lasso	4	0.30	2.4e-30	-10.94	-10.8	2.7e-27	1.00	0.02	0.98	FALSE
8	GTEx	Skin Sun Exposed Lower leg	CELSR2	0.18	0.05	lasso	6	0.06	8.1e-06	-9.36	-8.1	4.4e-16	0.75	0.01	0.97	FALSE
9	GTEx	Whole Blood	PSRC1	0.14	0.04	lasso	3	0.03	6.9e-04	-11.14	-11.2	3.8e-29	0.99	0.00	1.00	TRUE
10	ROSMAP	Brain Pre-frontal Cortex	PSRC1	0.33	0.21	bslmm	430	0.26	1.2e-32	-10.94	-9.3	1.2e-20	0.82	0.00	1.00	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	CELSR2	0.25	0.21	lasso	6	0.23	4.9e-29	-10.94	-10.9	9.1e-28	0.96	0.00	1.00	FALSE
12	YFS	Blood	PSRC1	0.25	0.18	enet	32	0.24	1.6e-76	-10.94	-9.5	2.4e-21	0.87	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	PSRC1	0.03	0.00	blup	49	0.02	5.7e-05	-9.36	-8.7	4.3e-18	0.80	0.02	0.92	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PSRC1	0.14	0.04	enet	13	0.07	2.7e-04	-11.04	-8.6	1.3e-17	0.73	0.01	0.82	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	CELSR2	0.12	0.00	enet	21	0.04	3.0e-03	-11.14	-6.2	4.5e-10	0.58	0.00	0.76	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	PSRC1	0.07	0.06	lasso	1	0.04	1.8e-03	-9.36	-9.4	7.7e-21	0.75	0.01	0.83	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSRC1	0.14	0.05	enet	6	0.08	7.5e-09	1.28	-5.6	1.9e-08	0.50	0.20	0.51	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSRC1	0.12	0.11	lasso	4	0.09	4.5e-06	-10.98	-10.9	1.2e-27	0.92	0.00	0.99	FALSE
19	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MYBPHL	0.09	0.07	blup	46	0.06	5.7e-04	-0.92	-7.0	2.3e-12	0.55	0.03	0.48	FALSE
20	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PSRC1	0.16	0.20	lasso	3	0.19	3.7e-09	-11.00	-11.1	2.2e-28	0.95	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SORT1	0.23	0.16	lasso	4	0.16	4.6e-08	-11.14	-11.2	4.3e-29	0.94	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PSRC1	0.07	0.03	enet	8	0.05	3.4e-04	-11.04	-8.4	3.2e-17	0.77	0.00	0.93	FALSE
23	The Cancer Genome Atlas	Soft Tissue Sarcoma	PSRC1	0.09	0.00	blup	49	0.02	3.1e-02	-4.79	-7.1	1.4e-12	0.67	0.01	0.36	FALSE
24	The Cancer Genome Atlas	Stomach Adenocarcinoma	PSRC1	0.12	0.03	enet	6	0.08	1.5e-06	-10.94	-7.8	4.6e-15	0.77	0.00	0.98	FALSE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	SORT1	0.04	0.01	blup	60	0.03	4.4e-03	-10.94	-7.8	7.3e-15	0.63	0.01	0.75	FALSE