Hub : Genes

GPSM2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1180	0.0320	5.3e-08	0.086	0.055	0.078	0.073	0.084	1.3e-10	2.4e-07	1.0e-09	3.4e-09	2.3e-10
2	GTEx	Cells Transformed fibroblasts	0.1160	0.0430	8.4e-04	-0.003	NA	0.010	NA	-0.004	5.7e-01	NA	5.6e-02	NA	9.3e-01
3	GTEx	Esophagus Mucosa	0.1690	0.0510	1.7e-04	0.022	NA	0.072	NA	0.038	1.3e-02	NA	1.5e-05	NA	1.5e-03
4	GTEx	Lung	0.1757	0.0508	2.3e-06	0.071	NA	0.109	NA	0.105	3.9e-06	NA	1.1e-08	NA	2.0e-08
5	GTEx	Pituitary	0.2710	0.0950	6.8e-03	0.035	NA	0.051	NA	0.096	4.6e-02	NA	2.1e-02	NA	2.2e-03
6	GTEx	Testis	0.2210	0.0760	2.5e-03	0.004	NA	-0.001	NA	-0.003	2.1e-01	NA	3.6e-01	NA	4.7e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.0627	0.0248	9.3e-04	0.019	0.015	0.019	0.016	0.016	1.3e-03	3.9e-03	1.5e-03	3.0e-03	3.1e-03
8	TCGA	Prostate Adenocarcinoma	0.0488	0.0246	5.7e-05	0.028	0.050	0.044	NA	0.037	5.2e-04	5.6e-06	2.1e-05	NA	9.5e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.3	0.5	2.4	0.1	0.5	1.6	0.3	-0.2	0.6	-0.2	-1.0
Bipolar Disorder or Schizophrenia	0.3	0.8	2.1	0.7	0.1	1.4	-0.5	-0.2	1.5	0.9	-0.7
Depressed Affect (Nagel 2018)	1.1	2.3	10.0	3.2	-0.2	0.1	-1.6	1.3	1.2	0.3	1.5
Depression (Nagel 2018)	0.6	0.9	2.2	1.5	0.5	0.9	-0.9	-1.3	1.0	-0.0	0.7
Intelligence (Savage-Jansen 2018)	1.4	4.3	18.7	-1.9	1.2	2.5	0.7	-4.3	0.7	-1.2	-1.5
Neuroticism (Nagel 2018)	0.3	0.8	3.1	1.8	0.9	0.8	-0.2	0.3	0.4	-1.1	-0.2
Schizophrenia (2018)	0.3	0.7	2.1	0.8	0.1	0.4	-1.1	-0.1	1.4	1.3	-0.1
Schizophrenia vs Biploar Disorder	0.3	0.5	1.5	0.9	0.2	-0.1	0.0	0.4	1.0	1.2	0.3
Worry (Nagel 2018)	0.6	1.2	3.6	0.2	1.8	0.6	0.9	-0.8	0.1	-1.9	-1.1
Alzheimer’s Disease (in mother)	0.9	1.0	2.8	0.8	-0.2	0.2	-1.7	-1.4	0.3	0.8	1.4
Alzheimer’s Disease (in father)	1.6	1.8	7.0	-1.0	-2.6	-0.8	-0.5	-1.0	-1.2	-1.0	1.4
Alzheimer’s Disease (including proxy)	0.9	1.3	3.4	0.1	-1.5	-0.4	-1.8	-1.2	-0.6	-0.4	1.7
Crohns Disease (2017)	0.9	1.9	7.2	2.7	-0.8	-1.6	-0.9	0.5	1.1	1.1	1.1
Irritable Bowel Disease (IBD)	0.5	1.3	5.4	2.3	-0.1	-0.6	-0.8	0.7	1.0	1.2	1.0
Ulcerative Colitis (UC)	0.4	0.8	2.7	1.6	0.1	0.5	-0.8	0.2	1.0	1.1	0.8
Major Depression (MDD)	0.8	1.0	2.0	0.8	-1.4	-0.5	-1.2	-1.4	-0.4	-0.4	1.3
Reaction Time	0.2	0.3	1.1	-0.2	0.5	-0.6	0.3	0.0	-1.0	-0.8	-0.1
Verbal and Numeric Reasoning (VNR)	1.6	3.7	16.2	-0.7	0.0	3.1	-0.7	-4.0	1.4	-0.6	-1.0
Breast Cancer	0.3	0.8	2.5	-0.3	0.4	-0.7	1.0	1.2	-1.6	-0.5	-0.4
Ovarian Cancer	1.4	1.8	4.3	0.6	-1.8	-1.1	-1.7	-1.1	-0.1	1.1	2.1
Prostate Cancer	0.5	0.7	2.0	-0.5	-1.1	0.9	0.2	-1.4	-1.0	-0.3	-0.0
Age at First Birth	0.8	1.2	5.3	-0.1	-2.3	-0.6	0.6	0.2	-1.7	-0.6	0.5
Bipolar Disorder (2011)	0.1	0.1	0.6	-0.4	-0.2	0.2	-0.3	0.1	-0.1	0.8	-0.1
Body Mass Index (BMI) (2010)	0.6	0.9	1.6	-1.2	0.3	1.1	1.2	-0.3	-0.2	-1.1	-1.2
Coronary Artery Disease (CAD)	3.0	3.6	10.8	0.4	2.4	-3.3	-0.8	2.4	0.5	2.1	0.9
Crohns Disease (2012)	0.4	0.6	2.0	1.3	-0.0	-1.4	0.4	1.0	-0.1	0.0	-0.1
Mean Putamen Volume	1.0	1.1	2.2	-1.1	1.1	-0.9	0.4	1.5	-1.1	-1.2	-0.9
Fasting Glucose	2.1	2.5	6.4	1.2	-1.9	-0.4	-2.5	-0.8	-0.8	1.3	2.4
HbA1C	0.4	0.5	1.7	-0.2	0.1	-0.1	-0.5	-0.0	-0.7	-1.3	-1.1
HDL Cholesterol	4.0	6.7	19.3	-1.2	-1.3	4.4	1.9	-3.2	0.5	-3.0	-2.8
LDL Cholesterol	24.1	38.2	146.4	1.0	12.1	-8.5	-1.2	8.6	-1.3	3.0	-0.2
Lupus	0.6	0.9	1.6	1.2	-1.2	-1.0	-1.2	0.1	0.2	0.5	1.2
Neuroticism (2016)	0.5	0.7	2.0	-0.3	1.0	0.6	-0.0	1.4	-0.5	-1.1	-0.9
Primary Biliary Cirrhosis	0.3	0.4	1.4	0.3	0.1	1.2	-0.2	-1.2	0.4	0.1	-0.5
Rheumatoid Arthritis	0.4	0.5	1.6	-0.0	0.9	0.0	0.9	1.2	0.2	0.3	-0.7
Schizophrenia (2014)	0.2	0.4	1.2	0.3	1.1	0.6	-0.6	0.1	0.9	0.4	-0.3
Triglycerides	1.6	2.7	9.1	-1.9	0.3	-2.6	0.4	0.9	-3.0	0.3	0.8
Type 2 Diabetes (T2D) (2012)	1.7	2.0	5.2	-2.0	-0.5	1.0	1.1	-0.1	-1.5	-2.3	-1.4
Ulcerative Colitis	0.3	0.4	1.8	-0.1	0.4	0.2	1.3	0.8	-0.4	-0.1	-0.4
Blood Eosinophil Count	0.2	1.2	6.6	-0.9	0.4	-2.6	0.9	-0.4	-0.8	-0.5	-0.2
Blood Platelet Count	0.2	1.9	4.5	0.9	-0.7	-2.1	-1.3	-0.8	-1.9	-0.4	1.7
Blood Red Count	0.4	3.5	7.7	2.8	-1.1	-2.1	-2.5	0.2	0.7	1.2	2.6
Blood White Count	0.9	6.5	14.1	2.5	-3.7	-3.4	-2.4	-0.3	-0.2	0.8	3.8
Heel T-Score	0.1	0.5	1.8	-0.4	-1.0	-0.2	0.4	-0.9	-1.4	-0.3	0.3
BMI	0.2	1.2	3.9	0.5	2.0	-0.2	-1.0	-1.8	1.2	0.1	0.2
Height	0.2	3.3	18.7	1.6	-4.3	1.5	-0.3	-0.9	0.5	0.4	1.3
Waist Hip Ratio (WHR)	0.2	1.1	3.1	1.6	-0.2	1.5	-0.5	0.1	1.8	0.5	-0.2
Systolic Blood Pressure	0.2	1.2	3.1	1.0	-0.4	-0.0	-1.8	0.7	0.7	1.6	1.2
Smoking Status	0.3	0.7	3.0	-0.8	-1.7	0.9	0.3	-0.8	-0.3	-0.7	-0.1
Allergy or Eczema	0.3	0.8	1.9	-1.4	-0.5	1.1	0.3	-0.8	-0.7	-1.1	-0.7
Cardiovascular Disease	2.2	7.2	14.1	1.9	2.9	-2.8	-3.3	2.8	0.6	3.8	2.0
Hypothyroidism (self reported)	0.5	1.2	3.8	-0.7	1.2	-0.9	-0.4	2.0	-0.2	1.5	0.1
Respiratory disease	0.4	0.9	4.0	-0.1	-0.7	2.0	-0.3	-1.4	0.9	-0.2	-0.2
Type 2 Diabetes (T2D) (2018)	0.6	1.1	5.1	0.6	-1.3	-0.8	-0.1	2.2	-0.7	0.7	0.6
Lung FEV1/FVC ratio	0.5	2.5	6.9	1.1	0.3	-2.1	-1.3	1.0	-0.6	2.0	2.6
Lung FVC	0.2	1.3	3.9	0.3	-2.0	-1.5	-0.4	1.0	-1.5	0.7	0.3
Neuroticism	0.4	1.0	3.2	0.8	0.5	1.8	-0.7	-0.1	1.4	-1.1	-0.2
Chronotype (morning person)	0.3	0.8	3.1	-1.3	-0.7	-0.5	0.5	-0.4	-1.8	0.4	-0.5
Hair Pigment	0.0	0.7	1.9	1.1	-0.5	-1.1	-0.4	0.7	-1.4	-0.3	0.8
Tanning	0.1	1.4	3.0	-1.2	-1.7	1.7	1.3	-0.7	-0.1	-0.7	-1.1
Hand grip strength (left)	0.3	0.8	3.2	-0.1	-0.8	1.2	0.9	-1.8	-0.3	-0.1	-0.2
Number of treatments/medications taken	1.4	2.5	8.1	0.3	2.8	-0.5	-1.7	1.8	1.5	1.7	0.6
Average weekly spirits intake	0.2	0.3	0.8	-0.3	-0.9	-0.3	0.1	-0.1	-0.8	-0.7	0.5
Sensitivity / hurt feelings	0.4	0.6	1.9	0.3	0.4	1.1	0.3	-0.4	0.2	-1.1	-1.4
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.5	0.5	1.9	1.3	0.5	-1.2	1.1	-0.5	-0.6
Hearing difficulty/problems: Yes	1.0	1.6	6.4	-0.3	-2.5	1.0	0.6	-0.9	1.8	0.8	0.2
Relative age of first facial hair	0.1	0.2	0.8	0.4	-0.9	0.1	-0.1	0.5	-0.5	0.2	0.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	3.2	0.4	1.8	-0.0	-0.7	-0.2	0.7	0.1	-0.3
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.3	0.5	0.3	-1.0	-0.6	0.6	0.4	0.8	1.1
Ever had hysterectomy (womb removed)	1.0	1.1	3.3	-0.5	1.4	1.2	0.6	0.6	0.7	-1.0	-1.8
Systolic blood pressure, automated reading	0.1	0.2	0.8	-0.3	0.5	0.2	-0.2	-0.9	-0.2	-0.6	-0.3
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	4.1	0.2	-2.0	0.7	-1.0	1.6	0.5	1.1	1.0
Angina	1.2	1.6	4.2	0.1	2.1	-1.3	-0.5	2.0	-0.3	1.6	0.5
Medication for hormone replacement therapy	0.6	0.7	3.1	-1.8	-0.7	0.1	0.8	-0.8	-0.3	-0.7	-0.1
Vitamin and mineral supplements	0.6	0.8	2.0	-0.4	0.6	-1.2	0.9	0.9	-1.4	-0.9	0.2
Supplements: Zinc	0.8	0.9	2.6	-0.9	0.7	0.5	0.8	-0.6	-0.9	-1.6	-1.0
Medication: Co-codamol	1.5	1.7	5.1	-1.2	2.2	-0.2	1.8	0.5	0.0	-1.4	-1.4
Medication: Metformin	0.2	0.3	1.2	0.0	-0.9	-0.1	0.2	1.1	-0.3	0.5	0.3
Diabetes (father)	1.0	1.2	2.8	-1.2	-0.4	1.7	1.2	0.7	-0.4	-1.4	-1.1
Diabetes (mother)	0.5	0.6	2.8	-0.1	-1.4	0.1	-0.0	1.7	-0.3	-0.1	0.2
Severe depression (siblings)	0.3	0.3	1.2	0.4	-0.7	0.1	0.2	0.3	-1.1	0.4	0.4
Pack years adult smoking proportion	0.5	0.8	3.4	-0.5	0.4	-1.5	-0.2	1.8	-0.6	0.3	-0.1
Impedance of leg (right)	0.1	0.5	1.4	0.6	-0.4	-1.1	-0.1	1.0	0.3	0.4	1.2
Leg fat-free mass (left)	0.1	0.6	2.4	0.9	0.0	0.9	-0.3	-1.5	0.7	-0.1	-0.4
Trunk fat percentage	0.3	1.3	7.1	-0.2	2.7	-0.2	-0.1	-0.5	1.3	-1.0	-0.7
Hand grip strength (right)	0.4	1.1	4.7	-0.1	-2.2	0.8	0.6	-1.5	-0.2	0.7	0.4
Townsend deprivation index at recruitment	1.5	2.1	5.8	2.4	-1.4	-0.9	-1.5	0.4	0.2	2.0	1.4
Current tobacco smoking	0.4	0.6	2.9	-0.2	-0.2	-0.5	0.5	1.7	-0.7	-1.1	-0.2
Average weekly fortified wine intake	0.7	0.8	1.8	-0.2	1.4	0.5	-0.0	-0.7	1.0	-1.3	-0.9
Maternal smoking around birth	1.4	2.1	6.5	-0.6	2.5	0.1	0.3	2.5	-0.5	0.5	-1.7
Fed-up feelings	1.3	2.4	7.7	2.8	-0.9	-0.1	-2.2	0.6	1.5	0.8	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	3.7	1.9	1.8	0.9	-1.0	-0.4	1.2	-0.5	-0.3
Relative age voice broke	0.4	0.6	2.8	-0.2	0.2	-0.4	0.4	-1.0	-0.6	-1.7	-0.8
Taking other prescription medications	0.4	0.6	3.9	0.1	2.0	0.1	0.0	-0.2	0.8	-0.4	-0.5
Age when periods started (menarche)	0.1	0.2	0.5	-0.5	0.7	0.1	0.5	0.3	0.4	-0.6	-0.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.8	-0.6	1.4	1.1	1.3	-0.4	-0.3	-1.3	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.5	0.5	-0.4	-0.7	-0.7	0.7	0.1	-0.0	-0.0
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.8	0.9	0.5	0.9	-0.8	-0.4	1.3	1.3	0.4
Qualifications: CSEs or equivalent	1.9	2.6	5.8	1.6	-0.4	-2.1	-1.3	2.4	-0.7	1.8	1.4
Serious illness, injury or assault to yourself	0.9	1.1	4.9	-0.7	1.2	-0.8	0.0	2.2	0.8	0.0	-0.7
High blood pressure	0.4	1.1	2.7	0.4	-1.0	0.5	-1.6	1.6	-1.1	0.2	0.8
Hayfever, allergic rhinitis or eczema	0.5	1.0	2.2	-1.4	-0.4	1.1	0.3	-0.7	-1.2	-1.5	-0.9
Multivitamins +/- minerals	1.1	1.3	3.4	0.4	-1.0	1.8	0.2	-1.7	1.2	1.3	-0.5
Stomach or abdominal pain in last month	0.2	0.2	0.8	-0.1	-0.2	0.9	-0.0	-0.4	0.4	-0.5	-0.5
Supplements: Glucosamine	1.4	1.8	4.2	-1.0	-0.2	1.2	1.6	-2.0	0.1	-1.7	-1.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.1	-1.1	0.3	0.3	0.8	-0.7	-0.6	-0.4	-0.8
Medication: Atenolol	2.0	2.5	9.9	-1.1	2.3	-0.8	1.2	3.1	-0.4	0.5	-1.2
Medication: Levothyroxine sodium	0.9	1.6	4.8	-1.5	1.4	-0.7	0.4	2.2	-1.4	-0.4	-0.8
Sitting height	0.4	3.0	6.8	2.6	-1.5	-1.3	-1.9	-0.5	1.1	1.4	2.6
Chronic bronchitis/emphysema (father)	0.5	0.6	1.5	-0.4	1.0	0.6	0.3	1.2	0.1	1.2	0.1
High blood pressure (mother)	0.2	0.3	0.8	0.4	-0.4	0.2	-0.9	0.5	-0.2	0.7	0.8
Body mass index (BMI)	0.3	1.4	7.8	-0.1	2.8	0.6	-0.3	-0.8	1.2	-0.0	-0.8
Impedance of leg (left)	0.2	0.9	2.4	0.7	-0.7	-1.3	-0.4	1.3	-0.0	0.1	1.6
Leg predicted mass (left)	0.1	0.6	2.3	0.9	0.0	0.9	-0.3	-1.5	0.7	0.0	-0.4
Trunk fat mass	0.3	1.1	4.8	-0.1	2.2	0.3	0.1	-0.9	1.2	-1.0	-0.8
Waist circumference	0.3	0.9	3.1	0.6	1.8	1.0	-0.6	-0.3	1.5	-0.1	-0.5
Number of incorrect matches in round	0.4	0.7	2.1	0.4	-1.2	-0.5	-0.1	-0.7	-1.4	-0.1	1.0
Past tobacco smoking	0.4	0.7	2.3	0.1	1.3	-0.7	0.5	1.5	0.4	-0.3	-0.4
Alcohol usually taken with meals	0.1	0.2	0.6	-0.1	-0.2	0.6	-0.4	-0.8	0.3	-0.2	-0.3
Nervous feelings	0.5	0.9	2.8	0.1	1.1	1.7	0.9	-0.9	0.7	-0.7	-0.9
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	9.8	0.7	3.1	1.8	-0.1	-0.4	1.8	-0.8	-1.2
Hearing difficulty/problems with background noise	0.4	0.7	2.7	-0.4	-0.2	1.6	0.4	-0.5	1.4	-0.2	-0.5
Hair/balding pattern: Pattern 2	0.7	1.0	3.8	1.3	-0.4	0.2	-1.0	-1.9	0.5	0.4	0.8
Had menopause	0.1	0.1	0.6	0.0	-0.1	0.8	0.3	-0.2	0.0	0.0	0.1
Had other major operations	0.6	0.7	1.5	0.7	1.0	-0.3	-0.8	0.7	-0.2	1.2	1.2
Forced vital capacity (FVC)	0.5	1.8	7.3	1.5	-2.7	-0.8	-0.7	-1.1	-0.8	0.7	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.7	0.3	0.1	-0.1	-0.1	-0.6	0.4	-0.8	-0.6
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.1	0.8	1.7	-0.9	0.2	-2.0	-0.1	-0.7	-0.6
Qualifications: None of the above	0.6	1.3	5.7	-0.2	0.3	-1.6	0.2	2.4	0.2	-1.1	-0.6
Financial difficulties in last 2 years	0.5	0.6	2.3	0.1	-0.8	0.2	-1.1	-1.5	0.8	0.1	0.2
Mouth/teeth dental problems	0.1	0.1	0.2	0.3	0.1	-0.4	-0.4	-0.3	-0.3	0.3	0.4
Heart attack	1.5	1.9	7.7	0.4	1.9	-2.8	0.4	1.5	-0.2	0.6	0.6
Allergy	0.2	0.4	0.7	0.5	-0.2	-0.9	-0.5	0.8	-0.0	0.8	0.8
Pain all over the body in last month	0.8	0.8	2.6	0.7	0.9	1.0	-1.6	-0.1	0.9	0.8	0.6
Diabetes (self-reported)	0.5	0.8	3.6	0.7	-0.5	-0.7	-0.5	1.9	0.0	1.0	0.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	3.1	-0.5	-0.5	1.8	0.5	-0.1	0.0	0.6	-0.5
Medication: Ramipril	1.3	1.7	4.3	0.8	0.5	-2.1	-0.8	1.8	0.5	1.8	1.2
Medication: Simvastatin	8.0	11.8	29.5	2.3	4.4	-5.4	-3.0	4.8	-1.2	2.0	1.7
Fluid intelligence score	0.9	1.9	6.0	-1.0	-0.4	2.5	0.5	-2.1	-0.1	-1.3	-1.4
Illnesses of siblings	1.1	1.6	7.4	0.3	-2.2	-0.0	0.1	-2.7	-0.4	-0.7	0.1
Neuroticism score	0.4	0.8	2.4	0.8	0.5	1.3	-0.4	0.0	0.8	-1.5	-0.6
Weight	0.2	0.8	1.9	0.8	1.2	0.7	-0.5	-1.4	1.2	-0.2	-0.1
Impedance of arm (right)	0.1	0.6	3.0	0.1	-0.4	-1.7	-0.4	0.7	-0.1	-0.9	0.6
Arm fat percentage (right)	0.4	1.6	8.8	-0.5	3.0	0.2	-0.1	-0.7	1.3	-0.7	-1.1
Trunk fat-free mass	0.3	1.6	4.3	1.7	-1.5	1.3	-0.9	-2.1	0.7	0.4	0.7
Hip circumference	0.2	0.8	3.5	0.3	1.9	-0.3	-1.0	-0.8	1.1	-0.3	0.2
Time employed in main current job	0.2	0.2	0.8	0.9	0.4	-0.1	-0.7	0.1	0.2	0.3	-0.0
Alcohol intake versus 10 years previously	0.9	1.4	4.8	1.2	-2.2	-0.9	-0.7	-1.1	0.6	1.0	0.7
Father’s age at death	2.1	2.8	6.4	-1.9	-2.5	2.0	1.1	-1.8	-1.3	-1.2	-0.8
Worrier / anxious feelings	1.5	2.8	5.5	-0.7	1.0	2.2	1.4	-1.9	1.2	-2.3	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.5	4.0	0.9	1.8	1.3	-1.6	-0.1	2.0	-0.1	-0.4
Falls in the last year	0.5	0.7	2.0	-1.4	-0.6	-0.8	0.8	1.2	-0.5	-0.6	-0.2
Hair/balding pattern: Pattern 3	0.9	1.4	4.2	-0.3	-1.9	-1.4	0.1	-0.2	-2.0	-0.9	0.5
Number of live births	1.3	1.8	5.6	-0.5	2.4	-0.5	0.2	2.2	0.6	-1.0	-1.4
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	4.0	1.3	-2.0	-1.1	-0.7	-1.0	-1.0	0.7	1.0
Pulse rate	1.0	1.7	5.5	2.3	0.6	-0.4	-1.4	1.1	0.7	1.6	1.2
Happiness	1.4	1.7	4.8	0.1	0.9	2.2	0.1	-1.5	1.2	-1.6	-1.2
Noisy workplace	2.9	3.6	12.6	-2.2	0.6	-0.5	1.9	-1.2	-0.7	-3.5	-2.3
Qualifications: A levels/AS levels or equivalent	0.7	1.5	5.1	-1.1	0.3	2.2	0.7	-1.9	0.2	-0.3	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.4	1.1	-0.4	-0.2	-1.2	-0.3	0.9	0.8	0.9
Mouth/teeth dental problems: Dentures	0.2	0.3	1.1	0.5	-0.5	0.6	-0.1	0.3	1.0	0.1	-0.4
Asthma	0.6	1.2	5.4	1.2	0.5	0.7	0.4	-2.3	1.2	0.2	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.3	0.0	-0.1	0.7	0.4	-1.2	1.0	0.2	-0.1
Medication: Cholesterol lowering	8.0	12.4	32.4	1.2	5.0	-4.9	-2.3	5.7	-0.7	2.7	1.5
Depression (self-reported)	0.4	0.5	2.6	-0.6	1.6	0.7	0.5	-0.1	-0.2	-0.2	-0.3
Medication: Lansoprazole	1.3	1.5	7.3	-0.2	2.7	-0.1	0.0	0.6	0.8	-1.1	-1.5
Prospective memory result	2.2	2.7	4.5	-2.1	0.7	1.0	1.8	1.2	-1.8	-2.1	-1.8
Lung cancer (father)	0.5	0.5	1.3	-0.2	-1.0	0.3	0.8	-0.7	-0.7	-1.1	-0.5
Illnesses of mother	0.8	1.0	3.1	-0.0	1.4	0.6	0.7	-1.8	1.0	-0.8	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	3.6	1.3	-1.9	-1.2	-0.9	-0.8	-1.2	1.0	1.0
Pulse wave Arterial Stiffness index	1.0	1.2	3.7	-0.2	0.4	1.3	-0.9	1.7	1.9	0.3	-0.5
Impedance of arm (left)	0.1	0.6	2.4	0.0	-0.7	-1.6	-0.6	0.5	-0.1	-0.5	0.9
Arm fat mass (right)	0.3	1.4	6.3	-0.1	2.5	0.7	0.1	-1.4	1.2	-0.5	-0.9
Trunk predicted mass	0.3	1.6	4.5	1.7	-1.4	1.3	-0.8	-2.1	0.7	0.5	0.7
Standing height	0.3	2.8	11.9	2.1	-3.5	0.5	-0.6	-1.5	0.5	-0.3	1.6
Length of working week for main job	1.6	1.7	5.1	1.1	-0.7	1.6	-1.3	-2.2	1.5	-0.4	0.2
Exposure to tobacco smoke at home	0.7	0.8	2.7	-1.0	1.0	-0.1	0.2	1.6	-0.4	-0.7	-0.8
Breastfed as a baby	0.2	0.3	0.8	-0.5	-0.9	0.4	0.7	-0.6	-0.2	-0.5	-0.1
Tense / ‘highly strung’	0.3	0.5	2.4	0.7	1.5	0.4	0.5	0.6	-0.1	-0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.0	-0.2	0.7	1.0	0.1	-0.9	0.4	0.2	-0.3
Hair/balding pattern: Pattern 4	1.4	3.4	7.0	-1.8	1.5	2.1	1.9	2.4	0.5	-0.4	-2.6
Birth weight of first child	1.5	2.7	5.7	-2.0	1.2	1.4	2.4	0.1	-1.5	-1.4	-2.1
Peak expiratory flow (PEF)	0.6	1.3	5.4	0.4	-2.3	-0.5	-0.7	-1.1	-0.8	1.0	1.2
Pulse wave reflection index	0.7	0.8	2.5	-1.6	0.9	1.1	0.7	0.2	0.3	-0.9	-1.0
Ever highly irritable/argumentative for 2 days	1.8	2.1	4.8	-0.8	0.4	2.1	1.6	-1.1	-0.5	-1.7	-2.2
Loud music exposure frequency	1.7	1.8	3.7	1.9	-0.8	-1.3	-1.5	1.3	0.7	1.5	1.3
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	7.1	-2.0	-0.5	2.7	0.1	-2.3	0.1	0.5	-0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	-1.0	-0.3	-0.1	0.6	-0.5	-0.6	0.1	-0.1
Blood clot in the leg (DVT)	0.1	0.2	0.5	0.2	0.7	0.4	0.2	0.7	-0.3	0.2	-0.3
Medication: Paracetamol	0.5	0.8	1.7	1.3	-1.0	-0.8	-1.0	-0.3	0.7	0.4	1.2
Headache pain in last month	0.6	1.0	2.2	1.3	-0.9	-0.5	-1.3	0.3	0.4	1.0	1.5
Medication for cholesterol, blood pressure or diabetes	3.4	5.7	20.6	0.1	-2.0	3.5	1.3	-4.5	2.0	-1.5	-0.7
Glaucoma (self-reported)	0.5	0.6	1.5	0.5	-1.0	-1.0	0.6	0.1	-1.2	0.6	0.3
Gout (self-reported)	0.4	0.6	1.8	0.6	-1.1	0.4	0.0	0.9	0.4	1.3	0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.8	-0.6	1.4	-0.6	-0.2	0.5	-0.1	0.6	-0.1
Medication: Amlodipine	1.6	2.3	5.6	-1.8	-1.0	-2.4	0.7	1.8	-2.1	-0.5	-0.5
Medication: Ventolin 100micrograms inhaler	1.0	1.3	5.4	0.6	-0.6	1.5	0.5	-2.3	1.1	-0.2	-0.5
Birth weight	0.4	0.9	2.0	-1.3	1.4	0.2	0.2	1.3	-0.8	0.3	-1.0
Chronic bronchitis/emphysema (mother)	2.6	3.1	14.7	-0.9	2.2	0.2	1.3	3.8	-0.4	-0.2	-1.5
High blood pressure (siblings)	1.2	1.7	7.4	-0.1	1.9	-0.4	-0.9	2.7	-0.3	1.0	0.5
Forced vital capacity (FVC), Best measure	0.5	1.7	6.9	1.2	-2.6	-1.0	-0.5	-0.9	-1.4	0.7	0.8
Body fat percentage	0.4	1.7	9.7	-0.5	3.1	0.1	0.2	-0.3	1.1	-1.1	-1.1
Leg fat percentage (right)	0.3	1.2	7.5	-0.6	2.7	-0.1	0.3	0.1	0.7	-0.6	-0.9
Arm fat-free mass (right)	0.2	1.3	4.1	1.5	-0.1	1.6	-0.6	-2.0	0.9	0.2	0.2
Exposure to tobacco smoke outside home	0.2	0.3	0.7	0.4	-0.9	0.1	-0.7	0.8	-0.1	0.3	0.5
Comparative body size at age 10	0.7	1.9	5.4	-1.6	1.1	-0.3	1.1	0.5	-2.3	-1.4	-1.5
Number of full brothers	0.2	0.2	1.1	-1.1	0.1	0.0	0.7	0.5	-0.0	0.2	0.2
Worry too long after embarrassment	1.0	1.7	7.1	-0.9	0.6	0.6	0.9	0.6	-1.0	-2.7	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.8	-1.0	0.6	1.7	0.4	-0.3	0.3	-0.6	-1.1
Wheeze or whistling in the chest in last year	0.5	0.9	4.2	0.9	-0.5	1.1	0.4	-2.1	0.9	-0.0	0.3
Number of children fathered	0.6	0.7	1.3	-0.7	0.9	0.4	1.1	0.5	1.0	0.7	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.4	0.8	-0.4	1.3	-0.5	0.6	0.5	1.6	0.0
Age at first live birth	0.4	0.8	4.2	0.5	-0.8	-0.2	-0.2	-2.0	0.2	0.3	1.0
Pulse wave peak to peak time	1.1	1.3	3.2	0.5	-0.7	-1.4	0.8	-1.8	-1.8	-0.1	0.9
Health satisfaction	3.0	3.9	16.2	-1.3	4.0	2.0	1.5	0.4	1.2	-1.0	-2.1
Shortness of breath walking on level ground	1.2	1.4	3.5	-0.5	1.4	1.5	1.1	-0.7	1.0	-1.1	-1.9
Qualifications: College or University degree	0.6	1.8	5.9	0.3	1.0	2.4	-0.4	-2.1	1.6	0.6	-0.1
Eye problems/disorders: None of the above	0.2	0.2	0.9	-0.4	0.6	-0.1	0.1	1.0	0.1	0.2	-0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.0	-0.5	-1.0	-0.6	-0.1	0.0	-0.5	0.6	0.5
Emphysema/chronic bronchitis	0.5	0.6	2.0	0.6	-0.1	0.9	0.2	1.4	1.0	0.2	-0.6
Medication for pain relief, constipation, heartburn	0.6	1.1	2.5	-1.6	-1.2	1.1	1.2	-1.2	-0.4	-0.2	-0.8
Neck or shoulder pain in last month	0.6	0.8	1.7	-0.8	0.8	-0.8	1.0	1.3	-0.8	-0.8	-0.9
Medication: Blood pressure	1.2	2.1	4.9	-0.9	-1.3	-1.8	-0.9	2.2	-2.0	0.9	0.6
Angina (self-reported)	1.4	1.9	5.9	-0.1	2.4	-1.4	-0.1	2.2	-0.2	1.5	0.1
Migraine (self-reported)	0.4	0.4	1.2	-0.8	-0.4	-0.9	-1.1	-0.3	-0.5	0.4	0.4
Medication: Ibuprofen	0.6	0.7	2.6	-0.1	0.7	1.2	0.2	-0.7	1.6	0.2	-0.5
Medication: Allopurinol	1.0	1.4	4.8	1.0	-0.3	0.3	-0.2	1.8	1.4	2.2	0.3
Medication: Omeprazole	1.1	1.3	3.1	-1.3	1.5	0.2	1.0	-0.6	-0.7	-1.8	-1.4
Medication: Seretide 50 evohaler	0.1	0.1	0.6	-0.2	-0.2	0.0	0.3	0.5	0.3	-0.8	-0.2
Mean time to correctly identify matches	0.3	0.6	1.6	-0.4	-0.1	-0.1	0.4	0.9	-1.2	-1.3	-0.4
Heart disease (mother)	0.6	0.8	2.0	1.2	0.7	-1.4	-0.4	1.2	0.2	0.5	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.1	-0.7	-0.5	-0.1	0.6	-1.1	-1.0	-0.9	-0.4
Whole body fat mass	0.3	1.4	6.1	-0.4	2.5	0.7	0.4	-0.8	1.2	-1.0	-1.2
Leg fat mass (right)	0.3	1.1	5.7	-0.2	2.4	0.4	0.5	-0.4	0.9	-0.5	-1.0
Arm predicted mass (right)	0.4	1.8	5.9	1.9	-0.5	1.5	-0.7	-2.4	1.2	0.4	0.4
Pulse rate, automated reading	1.3	4.3	10.3	3.2	0.2	-1.5	-2.6	0.0	1.1	2.7	2.6
Alcohol intake frequency.	0.8	1.9	5.0	2.2	-0.2	-0.2	-2.1	0.5	1.9	0.7	1.1
Comparative height size at age 10	0.2	1.3	5.0	0.8	-1.8	-0.3	0.4	-0.4	-1.0	-2.2	0.2
Number of full sisters	1.1	1.3	4.2	0.3	1.3	-1.3	-0.1	2.0	-0.8	-1.5	0.2
Suffer from ‘nerves’	0.4	0.6	1.3	-1.2	0.9	-0.2	0.6	0.4	-0.8	-0.9	-0.7
Overall health rating	0.7	1.5	8.1	0.2	2.8	-0.1	-0.2	1.0	0.6	-1.3	-0.8
Chest pain or discomfort	0.3	0.4	2.7	0.0	1.6	-0.4	0.4	0.4	0.1	-0.4	0.3
Had major operations	0.7	0.8	3.2	0.9	0.8	-0.4	-0.7	1.8	0.8	0.6	0.1
Age at last live birth	1.2	1.7	3.9	1.2	-0.7	-1.1	-2.0	-1.5	1.0	0.7	1.8
Family relationship satisfaction	0.7	0.9	3.3	-0.3	1.8	1.0	0.7	-0.9	0.8	-0.4	-0.8
Leg pain on walking	1.2	1.5	3.9	1.8	0.6	0.1	-2.0	-0.5	1.8	-0.2	1.0
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.3	1.8	-0.6	-0.9	-1.4	-1.0	0.8	1.2	1.3
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.8	-0.6	0.1	-0.9	0.3	-0.0	-0.8	-0.4	0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.9	-0.1	0.4	0.3	0.9	-0.3	-0.5	-0.9	-0.8
Medication: Aspirin	2.4	3.1	13.4	0.3	1.9	-1.9	-1.4	3.7	-1.3	0.0	0.5
Supplements: Vitamin C	0.6	0.8	4.3	0.5	-0.2	0.3	-2.1	0.2	1.0	-0.1	0.5
Knee pain experienced in last month	0.6	0.9	4.4	0.5	2.1	0.0	-0.2	-0.4	1.0	-1.0	-0.4
Hypertension (Self-reported)	0.4	1.1	3.2	0.1	-0.8	-0.0	-1.6	1.8	-1.1	0.7	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.7	7.1	-0.7	2.7	-0.4	1.2	-0.6	-0.3	-1.6	-1.1
Illnesses of father: Heart disease	2.1	3.0	10.0	1.0	3.2	-1.6	-1.5	1.7	0.9	1.8	0.8
Illnesses of siblings: Diabetes	0.2	0.3	0.5	0.7	0.7	0.4	-0.6	0.5	0.3	-0.3	0.7
Smoking status: Previous	0.5	0.7	3.7	-0.0	-1.0	0.7	-0.6	-1.9	-0.4	0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.5	5.8	2.4	-2.4	0.3	-2.1	-1.7	1.7	1.6	1.8
Whole body fat-free mass	0.2	1.1	3.6	1.4	-0.7	1.3	-0.6	-1.9	0.7	0.1	0.1
Leg fat-free mass (right)	0.1	0.5	2.0	1.0	-0.3	0.7	-0.4	-1.4	0.4	-0.3	-0.2
Arm fat percentage (left)	0.4	1.6	8.4	-0.5	2.9	0.5	-0.1	-0.9	1.3	-0.7	-1.1
Average weekly red wine intake	0.7	1.0	3.3	-1.8	0.3	0.9	0.8	-0.5	-1.0	-0.8	-0.9
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.9	0.0	0.8	1.4	0.4	-1.2	0.4	0.2	-0.5
Mood swings	1.2	2.2	8.4	2.9	-1.0	-0.3	-1.8	0.9	0.7	0.2	1.8
Loneliness, isolation	2.1	2.9	10.3	3.2	-0.2	-1.6	-2.0	1.9	0.9	0.3	1.3
Long-standing illness, disability or infirmity	0.5	0.8	1.6	-1.3	1.3	0.8	0.2	0.7	-0.1	-0.8	-1.2
Ever had bowel cancer screening	0.5	0.6	1.6	0.4	0.8	-1.0	-0.7	1.3	0.6	0.7	0.3
Diabetes diagnosed by doctor	0.5	0.8	2.5	0.7	-1.1	-0.4	-0.5	1.6	-0.3	1.1	0.8
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.1	6.9	0.9	-2.6	-1.4	-1.3	-0.1	-1.7	-0.7	1.5
Friendships satisfaction	1.3	1.6	3.4	-0.6	1.8	1.1	1.0	-1.2	1.0	-1.5	-1.5
Qualifications: nursing, teaching	0.8	1.3	2.8	-1.7	-0.7	-0.0	0.9	-1.2	-1.3	-1.5	-1.0
Commuting to job workplace: Walk	0.2	0.2	0.9	-0.3	-0.4	0.1	0.1	-0.9	-0.4	0.5	-0.4
Eye problems/disorders: Cataract	0.5	0.5	2.0	0.5	0.4	0.8	-0.5	-1.4	0.5	-0.9	0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.3	0.4	-0.2	-0.2	0.3	0.6	0.3	0.4	0.5
Medication for cholesterol	2.3	3.5	15.7	0.0	-4.0	0.9	1.4	-3.0	-0.4	-0.7	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.4	1.1	-1.3	-0.4	-1.5	-0.7	0.7	0.9	1.6
Back pain experienced in last month	0.4	0.6	1.5	1.2	0.0	-0.7	-0.7	0.9	1.0	0.0	0.6
Mineral and other dietary supplements	0.5	0.7	1.8	0.7	-0.5	-1.3	-0.3	0.9	-0.0	0.8	1.1
Breast cancer (self-reported)	2.2	2.6	10.9	-1.1	1.2	3.3	0.4	-1.0	1.7	-0.3	-1.8
Asthma (self-reported)	0.6	1.2	5.5	0.8	0.5	1.1	0.5	-2.3	1.2	0.2	-0.2
Osteoporosis (self-reported)	0.4	0.4	1.0	-0.0	1.0	0.8	-0.7	0.2	0.9	0.5	-0.5
Osteoarthritis (self-reported)	2.2	2.9	9.2	-0.3	3.0	2.7	0.9	0.2	1.4	-0.6	-1.8
Medication: Aspirin	2.4	3.2	13.3	0.5	2.1	-2.0	-1.3	3.6	-1.1	0.1	0.5
Medication: Gliclazide	2.0	2.3	6.0	1.3	0.7	0.5	-1.7	0.1	2.1	2.4	1.7
Illnesses of father: None of the above (group 1)	0.6	0.7	3.0	0.7	-1.7	-0.0	0.7	-1.3	0.1	-0.2	-0.2
Smoking status: Current	0.6	0.9	2.9	-0.8	-0.4	-0.3	0.9	1.7	-0.9	-1.2	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	4.0	0.6	-0.8	-2.0	-0.9	0.3	-0.8	1.9	0.9
Whole body water mass	0.2	1.2	4.0	1.4	-0.6	1.5	-0.6	-2.0	0.9	0.2	0.1
Leg predicted mass (right)	0.1	0.5	2.4	0.9	-0.5	0.7	-0.4	-1.5	0.3	-0.3	-0.2
Arm fat mass (left)	0.3	1.4	5.8	-0.0	2.4	0.7	-0.2	-1.3	1.4	-0.4	-0.7
Number of self-reported non-cancer illnesses	0.6	1.0	2.6	0.4	1.5	-1.2	-1.6	0.8	0.1	0.4	0.8
Average weekly champagne plus white wine intake	0.6	0.9	2.7	-0.6	-0.3	1.6	-0.4	-1.4	1.3	0.1	-0.2
Miserableness	1.1	1.9	6.5	2.0	1.5	1.2	-0.4	0.6	2.5	-0.4	-0.5
Guilty feelings	0.3	0.5	1.5	1.0	0.5	1.2	-0.5	0.5	0.6	-0.4	-0.4
Wears glasses or contact lenses	0.7	0.8	3.0	-0.3	-0.4	1.7	-0.7	-0.9	1.4	0.6	0.1
Ever taken oral contraceptive pill	1.6	1.8	3.2	-1.8	-0.5	0.6	1.6	-0.9	-1.0	-1.8	-1.6
Hearing aid user	0.9	1.0	3.6	0.3	-0.2	1.9	-0.8	0.3	1.8	0.6	-0.2
Mother’s age at death	0.3	0.4	1.7	-0.6	0.4	1.3	0.3	0.3	-0.3	-0.9	-0.4
Financial situation satisfaction	1.2	1.5	4.5	1.3	2.1	0.3	-1.0	-1.2	1.6	0.6	0.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.0	-1.7	-0.6	0.0	-0.7	-0.9	0.6	-0.3	-0.2
Commuting to job workplace: Public transport	1.1	1.4	3.1	1.7	-1.3	0.6	-0.9	-1.5	1.5	0.4	0.8
Eye problems/disorders: Glaucoma	0.3	0.4	1.1	0.3	-0.5	-1.0	0.2	-0.6	-1.1	0.3	0.3
Medication: Blood pressure	0.8	1.5	8.3	0.4	1.1	-0.5	-0.8	2.9	-1.0	0.3	0.4
Pain type(s) experienced in last month: Hip pain	0.5	0.7	3.1	-0.3	0.1	0.2	0.4	-1.1	-0.4	-1.8	-0.8
Supplements: Fish oil (including cod liver oil)	0.7	0.9	3.1	0.1	-0.7	1.6	-0.2	-1.8	0.8	0.1	-0.1
High cholesterol (Self-reported)	11.0	19.6	49.7	2.9	7.0	-6.8	-3.6	4.9	-0.0	3.3	2.2
Medication: Bendroflumethiazide	0.2	0.3	0.7	-0.1	0.1	0.8	-0.7	0.8	-0.1	-0.5	-0.5
Medication: Paracetamol	1.1	1.7	4.6	2.1	-0.0	-0.3	-1.5	-0.0	1.5	1.3	1.7
Medication: Lisinopril	0.3	0.4	1.6	-0.2	0.4	-0.1	-0.5	0.8	-0.8	1.3	0.5
Medication: Atorvastatin	5.0	6.2	27.7	0.1	5.3	-3.2	-0.7	3.0	-0.5	1.5	0.2
Illnesses of father: High blood pressure	2.7	3.3	8.3	1.1	-1.7	-1.8	-2.1	1.1	0.2	2.3	2.9
Alcohol drinker status: Never	0.3	0.4	1.5	-0.4	-0.1	0.6	-0.7	0.6	-0.2	-1.2	-0.2
Ever smoked	0.6	1.1	4.3	0.3	-2.1	-0.1	-0.8	-1.0	-0.7	0.7	1.3
Basal metabolic rate	0.2	1.0	3.4	1.3	-0.2	1.2	-0.6	-1.8	1.0	0.1	0.1
Leg fat percentage (left)	0.3	1.0	6.6	-0.4	2.6	-0.1	0.1	0.2	0.6	-0.8	-0.6
Arm fat-free mass (left)	0.2	1.3	3.6	1.6	-0.1	1.5	-0.7	-1.9	1.1	0.2	0.2
Number of operations (self-reported)	0.1	0.2	0.4	0.6	0.6	-0.3	-0.6	0.1	-0.2	0.3	0.4
Average weekly beer plus cider intake	1.2	1.7	4.8	-1.1	0.3	-1.0	2.2	1.7	-1.3	-0.4	-1.2
Irritability	0.2	0.4	1.3	0.2	0.6	1.1	-0.2	-0.7	-0.1	-0.5	-0.6
Risk taking	0.9	1.3	2.3	-0.9	-1.3	0.8	1.5	-1.1	-1.0	-1.4	-0.8
Ever had prostate specific antigen (PSA) test	0.7	0.9	2.3	-0.8	-1.5	-1.1	0.4	-0.4	-1.3	-0.6	0.7
Fractured/broken bones in last 5 years	0.5	0.6	1.2	-1.1	-1.0	-1.0	0.4	0.2	-0.7	0.9	0.3
Age started oral contraceptive pill	0.8	1.0	2.0	-1.4	1.1	-0.5	1.2	0.6	-0.1	-1.4	-1.0
Diastolic blood pressure, automated reading	0.4	1.2	3.5	1.1	0.1	1.4	-1.0	-1.9	1.3	0.4	0.2
Ever depressed for a whole week	1.2	1.5	6.7	-0.2	1.2	0.5	1.1	-2.6	-0.4	-1.1	-1.0
Unable to work because of sickness or disability	0.7	0.9	3.1	-0.3	1.8	0.4	-0.3	-0.9	1.3	-1.0	-0.7
Commuting to job workplace: Cycle	1.4	1.7	3.1	1.8	-1.2	-0.3	-1.8	-0.8	0.5	1.3	1.7
Myopia	0.4	0.5	2.1	-0.4	-1.1	-0.0	-0.5	1.4	-0.2	0.6	-0.2
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.7	-0.5	0.5	0.1	1.9	-1.9	1.1	-0.4	-1.0
Cholesterol lowering medication	7.2	10.7	32.9	2.1	5.7	-4.7	-2.3	4.2	-1.1	1.0	0.7
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.7	-0.9	1.6	-0.1	1.2	-0.5	-0.5	-2.2	-1.3
Pain experienced in last month	0.4	0.6	2.5	-0.4	-0.3	-0.9	-0.3	-0.2	-0.5	1.6	1.0
Supplements: Calcium	0.2	0.2	0.7	-0.1	-0.0	-0.3	-0.9	0.5	-0.4	0.6	0.4
Basal cell carcinoma (self-reported)	1.3	1.6	4.1	1.4	-0.1	-1.0	-1.7	0.8	-0.6	1.3	2.0
Heart attack/myocardial infarction (self-reported)	1.5	1.9	7.7	0.3	2.1	-2.8	0.6	1.6	-0.2	0.3	0.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.8	0.1	0.9	0.2	0.4	0.9	-0.5	0.2	-0.4
Heart disease (siblings)	1.4	1.7	5.6	0.7	2.4	-1.3	0.3	2.3	0.4	0.3	-0.4
Alcohol drinker status: Previous	0.5	0.6	1.0	0.3	1.0	-0.9	-0.8	0.7	0.9	0.7	0.2
Pack years of smoking	0.7	1.1	4.1	-0.6	0.2	-1.9	-0.2	2.0	-0.8	0.1	0.0
Impedance of whole body	0.1	0.6	2.1	0.2	-0.8	-1.4	-0.2	0.8	-0.1	-0.5	1.0
Leg fat mass (left)	0.3	1.0	5.4	-0.2	2.3	0.5	0.4	-0.4	0.9	-0.6	-0.9
Arm predicted mass (left)	0.3	1.3	3.1	1.6	-0.3	1.4	-0.7	-1.8	1.2	0.6	0.4