[Hub]/) : Traits : Medication: Atorvastatin :

chr2:26,854,065-28,414,302

Best TWAS P=2.12e-14 · Best GWAS P=3.15e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GTF3C2 0.06 0.09 lasso 8 0.08 7.2e-10 -3.9 5.2 2.2e-07 0.72 0.28 0.72 FALSE
2 CommonMind Brain Pre-frontal Cortex IFT172 0.06 0.09 enet 16 0.09 3.9e-11 -4.1 -5.4 8.5e-08 -0.75 0.48 0.52 FALSE
3 GTEx Esophagus Mucosa AC074117.10 0.12 0.14 lasso 8 0.14 2.1e-09 -5.2 5.9 3.9e-09 0.74 0.94 0.06 FALSE
4 GTEx Esophagus Muscularis NRBP1 0.07 0.04 lasso 6 0.04 1.3e-03 -5.2 6.0 2.2e-09 0.82 0.01 0.97 FALSE
5 GTEx Ovary AC074117.10 0.16 0.04 enet 9 0.05 2.0e-02 -4.1 5.5 3.0e-08 0.77 0.04 0.80 FALSE
6 GTEx Testis NRBP1 0.16 0.09 lasso 3 0.06 1.8e-03 -5.2 6.0 1.5e-09 0.80 0.03 0.96 FALSE
7 GTEx Testis AC074117.10 0.14 0.08 lasso 6 0.12 4.5e-06 -4.4 6.2 6.0e-10 0.85 0.05 0.94 FALSE
8 GTEx Thyroid FNDC4 0.24 0.10 enet 23 0.16 2.2e-12 -2.2 -5.3 1.2e-07 -0.69 0.67 0.33 FALSE
9 GTEx Vagina AC074117.10 0.14 0.04 enet 13 0.06 1.4e-02 -3.6 5.4 7.7e-08 0.72 0.08 0.57 FALSE
10 METSIM Adipose NRBP1 0.06 0.09 lasso 3 0.08 1.6e-12 -5.2 5.2 1.9e-07 0.67 1.00 0.00 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme NRBP1 0.15 0.10 lasso 2 0.10 5.8e-04 -5.2 5.2 2.6e-07 0.67 0.02 0.10 FALSE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FNDC4 0.13 0.06 lasso 2 0.05 1.1e-03 7.6 -7.6 2.1e-14 -0.99 0.00 0.96 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma FNDC4 0.24 0.09 enet 9 0.17 1.9e-16 -2.6 -5.3 1.2e-07 -0.70 0.41 0.59 FALSE