Best TWAS P=5.45e-13 · Best GWAS P=8.78e-14 conditioned to 0.0106
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | FAM208B | 0.10 | 0.03 | lasso | 4 | 0.03 | 0.0014 | -6.2 | -7.2 | 5.5e-13 | -0.70 | 0.02 | 0.90 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | IL15RA | 0.04 | 0.00 | blup | 112 | 0.01 | 0.0350 | -3.8 | 5.5 | 2.9e-08 | 0.11 | 0.08 | 0.06 | TRUE |