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chr9:99,581,811-102,081,250

Best TWAS P=1.35e-38 · Best GWAS P=2.84e-51 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
26	NTR	Blood	C9orf156	0.01	0.01	lasso	5	0.01	1.5e-03	-12.92	-13.0	1.4e-38	0.58	0.42	0.25	TRUE
27	YFS	Blood	ANP32B	0.03	0.02	lasso	9	0.02	1.9e-08	3.00	-8.9	6.5e-19	0.32	0.99	0.00	TRUE
23	GTEx	Testis	C9orf156	0.39	0.40	enet	14	0.41	1.1e-19	8.09	8.5	1.9e-17	-0.32	1.00	0.00	TRUE
6	GTEx	Brain Cortex	C9orf156	0.51	0.32	enet	11	0.29	8.1e-09	8.09	8.2	2.2e-16	-0.29	0.92	0.02	TRUE
16	GTEx	Esophagus Gastroesophageal Junction	TSTD2	0.21	0.04	enet	29	0.07	2.0e-03	-2.85	-7.6	4.0e-14	0.45	0.12	0.22	TRUE
19	GTEx	Ovary	C9orf156	0.39	0.23	enet	15	0.18	3.9e-05	8.09	7.2	5.7e-13	-0.23	0.27	0.06	TRUE
10	GTEx	Breast Mammary Tissue	C9orf156	0.30	0.20	enet	16	0.21	3.3e-11	7.94	7.1	1.2e-12	-0.25	1.00	0.00	TRUE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FOXE1	0.13	0.08	lasso	3	0.08	7.0e-06	-2.72	-5.5	3.8e-08	0.22	0.13	0.77	TRUE
18	GTEx	Nerve Tibial	C9orf156	0.20	0.17	lasso	4	0.15	7.9e-11	8.09	5.5	5.1e-08	-0.15	1.00	0.00	TRUE
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NCBP1	0.16	0.02	blup	40	0.06	1.5e-03	4.36	5.4	8.4e-08	-0.28	0.02	0.30	TRUE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	COL15A1	0.04	0.03	lasso	6	0.04	5.5e-05	4.21	5.2	2.5e-07	0.06	0.18	0.32	TRUE
2	GTEx	Artery Coronary	TMOD1	0.18	0.01	enet	11	0.11	1.8e-04	-1.50	-5.1	3.1e-07	0.29	0.07	0.14	TRUE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	C9orf156	0.18	0.23	lasso	4	0.23	1.9e-25	8.09	8.7	4.2e-18	-0.32	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C9orf156	0.07	0.03	lasso	2	0.03	2.1e-04	8.09	8.2	2.9e-16	-0.30	0.36	0.11	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	C9orf156	0.29	0.15	lasso	5	0.13	1.0e-12	8.09	8.1	4.9e-16	-0.29	1.00	0.00	FALSE
4	GTEx	Brain Cerebellar Hemisphere	C9orf156	0.26	0.22	lasso	2	0.14	1.9e-04	8.09	8.1	6.0e-16	-0.28	0.26	0.06	FALSE
7	GTEx	Brain Frontal Cortex BA9	C9orf156	0.15	0.28	lasso	1	0.26	1.1e-07	8.09	8.1	6.0e-16	-0.28	0.50	0.06	FALSE
11	GTEx	Breast Mammary Tissue (Male)	C9orf156	0.13	-0.01	enet	1	-0.01	5.6e-01	8.09	8.1	6.0e-16	-0.28	0.05	0.06	FALSE
22	GTEx	Stomach	C9orf156	0.18	0.19	lasso	1	0.18	5.9e-09	8.09	8.1	6.0e-16	-0.28	0.98	0.00	FALSE
24	GTEx	Thyroid	C9orf156	0.21	0.26	lasso	1	0.26	7.9e-20	8.09	8.1	6.0e-16	-0.28	1.00	0.00	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	C9orf156	0.29	0.23	lasso	3	0.19	1.1e-06	7.95	8.0	8.7e-16	-0.31	0.74	0.03	FALSE
25	METSIM	Adipose	C9orf156	0.15	0.17	lasso	5	0.17	4.3e-25	8.09	8.0	1.9e-15	-0.27	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C9orf156	0.03	0.03	enet	2	0.03	1.1e-04	7.94	8.0	1.9e-15	-0.31	0.08	0.36	FALSE
9	GTEx	Brain Putamen basal ganglia	C9orf156	0.27	0.24	lasso	1	0.24	2.6e-06	7.94	7.9	2.1e-15	-0.31	0.24	0.04	FALSE
5	GTEx	Brain Cerebellum	C9orf156	0.30	0.27	lasso	7	0.24	8.1e-08	7.95	7.8	4.1e-15	-0.26	0.89	0.01	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	C9orf156	0.26	0.32	lasso	3	0.30	7.9e-09	7.94	7.8	4.7e-15	-0.29	0.79	0.01	FALSE
1	GTEx	Adipose Visceral Omentum	C9orf156	0.19	0.15	lasso	4	0.11	1.6e-06	8.09	7.8	6.1e-15	-0.27	0.91	0.00	FALSE
3	GTEx	Brain Caudate basal ganglia	C9orf156	0.40	0.40	lasso	4	0.39	3.1e-12	7.94	7.7	2.0e-14	-0.27	0.99	0.00	FALSE
15	GTEx	Colon Transverse	C9orf156	0.21	0.22	lasso	4	0.20	4.5e-10	7.95	7.5	9.1e-14	-0.28	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C9orf156	0.12	0.03	blup	46	0.09	9.0e-05	8.09	7.3	1.9e-13	-0.26	0.24	0.47	FALSE
12	GTEx	Breast Mammary Tissue (Female)	C9orf156	0.42	0.22	lasso	10	0.23	1.5e-07	8.09	7.3	2.9e-13	-0.22	0.49	0.03	FALSE
17	GTEx	Heart Left Ventricle	C9orf156	0.23	0.18	enet	13	0.16	9.3e-09	8.09	7.2	4.3e-13	-0.23	1.00	0.00	FALSE
35	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C9orf156	0.31	0.12	enet	7	0.11	3.4e-05	8.11	6.8	8.0e-12	-0.25	0.22	0.09	FALSE
28	YFS	Blood	CORO2A	0.03	0.01	bslmm	606	0.01	1.4e-04	-0.55	-6.7	2.3e-11	0.21	0.13	0.04	FALSE
21	GTEx	Skin Sun Exposed Lower leg	C9orf156	0.22	0.12	enet	16	0.18	1.3e-14	8.09	6.5	7.9e-11	-0.19	1.00	0.00	FALSE
14	GTEx	Colon Sigmoid	C9orf156	0.19	0.17	lasso	5	0.15	7.4e-06	7.95	6.3	2.8e-10	-0.22	0.51	0.03	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	C9orf156	0.16	0.11	lasso	2	0.10	5.1e-06	8.09	6.2	7.7e-10	-0.19	0.74	0.01	FALSE