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chr17:44,788,310-46,474,610

Best TWAS P=4.99e-10 · Best GWAS P=2.36e-10 conditioned to 0.000455

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	METSIM	Adipose	NPEPPS	0.04	0.02	lasso	6	0.03	1.4e-05	5.2	6.2	5.0e-10	0.70	0.05	0.95	TRUE
4	GTEx	Uterus	EFCAB13	0.41	0.03	lasso	9	0.28	1.7e-06	5.1	-6.2	6.9e-10	-0.23	0.04	0.46	TRUE
2	GTEx	Heart Atrial Appendage	TBKBP1	0.09	0.02	lasso	5	0.01	8.8e-02	4.5	5.6	2.5e-08	0.50	0.09	0.72	FALSE
1	GTEx	Breast Mammary Tissue (Male)	EFCAB13	0.11	0.09	lasso	1	-0.01	5.0e-01	-5.4	-5.4	7.4e-08	-0.71	0.05	0.14	FALSE
8	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TBKBP1	0.12	0.09	blup	46	0.08	8.4e-05	4.2	5.3	9.6e-08	0.84	0.08	0.78	FALSE
12	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TBKBP1	0.11	0.04	blup	45	0.03	5.3e-02	-5.4	5.3	1.2e-07	0.79	0.02	0.69	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	TBKBP1	0.02	0.03	lasso	2	0.03	3.0e-06	-5.4	5.3	1.5e-07	0.71	0.40	0.57	FALSE
9	The Cancer Genome Atlas	Colon Adenocarcinoma	TBKBP1	0.09	0.06	blup	46	0.09	7.8e-06	4.2	5.2	2.0e-07	0.80	0.13	0.83	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TBKBP1	0.07	0.06	lasso	8	0.07	5.1e-08	-5.4	5.2	2.1e-07	0.79	0.50	0.50	FALSE
11	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C17orf57	0.28	0.16	lasso	6	0.15	1.4e-07	-4.0	-5.2	2.1e-07	-0.56	0.47	0.46	FALSE
6	METSIM	Adipose	TBKBP1	0.08	0.10	lasso	4	0.10	2.1e-14	4.2	5.2	2.6e-07	0.85	0.46	0.54	FALSE
3	GTEx	Testis	EFCAB13	0.25	0.26	enet	18	0.25	2.4e-11	4.3	-5.1	2.9e-07	-0.40	0.96	0.04	FALSE