TWAS hub - C17orf57

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.061	0.0270	1.3e-05	0.079	0.066	0.068	NA	0.044	3.4e-07	2.8e-06	2.1e-06	NA	1.3e-04
2	TCGA	Breast Invasive Carcinoma	0.154	0.0432	0.0e+00	0.130	0.130	0.148	NA	0.140	1.5e-25	1.3e-25	4.2e-29	NA	1.4e-27
3	TCGA	Colon Adenocarcinoma	0.399	0.0890	1.1e-16	0.149	0.267	0.251	NA	0.238	5.7e-09	1.1e-15	1.0e-14	NA	6.1e-14
4	TCGA	Esophageal Carcinoma	0.398	0.1200	7.5e-04	0.040	0.096	0.044	NA	0.021	2.0e-02	5.9e-04	1.6e-02	NA	7.0e-02
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.135	0.0519	7.5e-08	0.037	0.070	0.075	NA	0.064	4.7e-05	2.8e-08	8.3e-09	NA	1.2e-07
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.292	0.0744	0.0e+00	0.174	0.199	0.204	NA	0.203	4.1e-19	6.4e-22	1.7e-22	NA	1.8e-22
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.150	0.0730	2.6e-03	0.051	0.047	0.028	NA	0.024	7.1e-04	1.0e-03	9.7e-03	NA	1.6e-02
8	TCGA	Liver Hepatocellular Carcinoma	0.279	0.0950	1.1e-07	0.159	0.126	0.150	NA	0.151	6.2e-08	1.6e-06	1.6e-07	NA	1.4e-07
9	TCGA	Lung Adenocarcinoma	0.178	0.0566	1.6e-12	0.069	0.117	0.129	NA	0.127	1.6e-08	1.5e-13	7.4e-15	NA	1.1e-14
10	TCGA	Lung Squamous Cell Carcinoma	0.128	0.0433	1.4e-09	0.056	0.090	0.090	NA	0.096	5.0e-07	2.3e-10	2.1e-10	NA	4.6e-11
11	TCGA	Ovarian Serous Cystadenocarcinoma	0.175	0.0700	1.1e-04	0.000	0.057	0.067	NA	0.021	3.2e-01	9.7e-05	2.7e-05	NA	1.3e-02
12	TCGA	Pancreatic Adenocarcinoma	0.167	0.0710	1.5e-04	0.109	0.059	0.036	NA	0.004	2.6e-05	1.8e-03	1.2e-02	NA	2.1e-01
13	TCGA	Pheochromocytoma and Paraganglioma	0.356	0.1060	2.9e-08	0.131	0.189	0.158	NA	0.127	7.1e-06	5.1e-08	7.7e-07	NA	9.5e-06
14	TCGA	Prostate Adenocarcinoma	0.443	0.0928	0.0e+00	0.176	0.248	0.261	NA	0.243	4.4e-18	1.1e-25	3.7e-27	NA	3.8e-25
15	TCGA	Rectum Adenocarcinoma	0.147	0.0870	7.6e-03	0.168	0.113	0.098	NA	0.103	9.3e-05	1.4e-03	2.8e-03	NA	2.1e-03
16	TCGA	Soft Tissue Sarcoma	0.169	0.0620	5.6e-07	0.130	0.118	0.115	NA	0.111	4.1e-08	1.7e-07	2.6e-07	NA	4.0e-07
17	TCGA	Stomach Adenocarcinoma	0.114	0.0630	7.3e-05	0.051	0.045	0.021	NA	0.055	1.5e-04	3.4e-04	1.1e-02	NA	8.2e-05
18	TCGA	Testicular Germ Cell Tumors	0.160	0.0750	4.7e-04	0.126	0.093	0.079	NA	0.091	3.4e-05	3.7e-04	9.7e-04	NA	4.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
LDL Cholesterol	16.4	25.9	40.6	6.0	5.8	4.2	5.0	3.7	6.4	4.1	5.5	4.1	3.4	2.9	4.9	4.7	5.5	6.1	5.2	5.9	6.3
High cholesterol (Self-reported)	11.4	20.1	30.6	5.5	4.7	4.8	2.7	4.3	4.4	2.8	5.3	4.3	4.3	2.5	4.9	3.8	4.5	4.7	5.3	5.4	4.9
Pulse wave Arterial Stiffness index	11.1	12.9	16.4	-3.7	-4.0	-3.2	-3.2	-3.7	-4.0	-3.2	-3.4	-3.8	-3.8	-2.8	-4.0	-3.9	-3.7	-2.8	-4.0	-3.7	-3.3
Pulse wave peak to peak time	9.0	10.6	13.5	3.3	3.5	3.1	2.9	3.5	3.6	2.9	3.1	3.5	3.6	2.5	3.7	3.6	3.3	2.4	3.7	3.3	2.8
Medication: Levothyroxine sodium	8.8	14.9	27.0	-4.3	-4.3	-2.4	-2.4	-2.8	-5.0	-3.8	-5.2	-3.4	-2.8	0.3	-3.8	-4.3	-3.7	-4.6	-4.2	-4.4	-4.8
Chest pain or discomfort	8.1	11.7	22.9	4.8	3.5	2.7	1.7	2.5	3.9	1.8	4.7	2.7	2.5	0.3	3.7	2.7	3.1	4.4	3.9	4.8	4.2
Medication: Atorvastatin	7.6	9.4	14.4	3.8	3.1	3.2	2.0	3.3	2.9	2.1	3.5	3.0	3.2	2.0	3.6	2.7	2.8	2.8	3.7	3.7	3.0
Medication: Cholesterol lowering	6.8	10.6	15.0	3.9	3.5	3.5	2.5	3.1	3.4	2.0	3.6	3.2	3.2	2.0	3.4	2.9	3.5	3.2	3.7	3.8	3.4
Birth weight	6.8	14.8	20.4	-4.0	-4.1	-3.8	-3.1	-4.0	-3.9	-3.2	-4.1	-3.9	-3.8	-3.2	-4.2	-3.8	-4.1	-3.5	-4.5	-4.0	-3.8
Hypothyroidism (self reported)	6.6	15.2	34.5	-4.4	-4.2	-1.6	-0.9	-3.1	-4.8	-3.5	-5.9	-3.8	-3.3	0.8	-4.4	-4.2	-3.3	-4.4	-4.5	-4.5	-4.4
Height	6.3	121.0	158.8	-12.2	-12.6	-10.3	-10.3	-9.1	-12.4	-9.4	-11.6	-10.6	-9.2	-8.1	-11.3	-10.6	-11.7	-11.3	-11.7	-12.2	-12.1
Alzheimer’s Disease (including proxy)	5.8	8.4	12.7	-2.6	-3.3	-2.3	-1.7	-3.2	-3.1	-3.0	-3.1	-3.4	-3.2	-2.8	-3.6	-3.4	-2.6	-2.1	-3.3	-2.4	-2.6
Medication for pain relief, constipation, heartburn	5.8	9.9	15.7	-4.0	-3.5	-2.1	-1.8	-2.8	-3.6	-2.5	-3.7	-2.7	-2.6	-1.8	-3.8	-2.7	-2.8	-3.6	-3.4	-3.9	-3.7
Irritability	5.8	9.8	14.2	3.4	3.3	3.0	2.1	3.2	3.4	2.3	3.8	3.5	3.1	2.0	3.5	3.2	3.2	2.6	3.8	3.3	2.9
Hypothyroidism/myxoedema (self-reported)	5.5	10.8	24.1	-3.9	-3.6	-1.6	-1.1	-2.1	-4.1	-2.7	-4.9	-2.6	-2.1	1.5	-3.3	-3.2	-3.0	-4.3	-3.6	-4.0	-4.2
Pulse wave reflection index	5.4	6.6	10.1	-2.5	-3.0	-1.9	-1.5	-2.8	-2.7	-2.4	-2.7	-3.1	-3.0	-2.2	-3.2	-2.8	-2.3	-1.8	-2.9	-2.5	-2.2
Medication: Paracetamol	5.3	8.7	11.9	3.2	3.1	3.1	2.8	3.0	3.3	2.5	3.1	2.3	2.3	1.4	2.8	3.0	3.3	3.2	3.4	3.1	3.5
Medication for cholesterol, blood pressure or diabetes	5.2	8.6	12.5	-3.3	-3.0	-3.5	-2.5	-2.6	-2.8	-2.2	-3.2	-2.5	-2.3	-1.8	-2.8	-2.4	-3.4	-3.4	-3.5	-3.3	-3.5
Triglycerides	5.0	8.2	10.6	-2.6	-3.3	-2.6	-2.0	-3.1	-2.9	-3.0	-3.0	-3.3	-3.2	-2.1	-3.2	-3.1	-3.0	-2.2	-3.2	-2.6	-2.6
Standing height	5.0	49.7	67.7	-7.8	-8.1	-6.7	-7.3	-5.3	-8.2	-5.8	-7.2	-6.4	-5.4	-5.2	-6.8	-6.7	-8.0	-7.7	-7.3	-7.8	-8.2
Cardiovascular Disease	4.9	16.2	26.2	4.7	3.9	4.1	2.2	3.8	3.4	3.5	5.0	3.3	3.4	2.6	4.3	3.3	3.8	5.0	4.8	4.6	5.1
Father’s age at death	4.7	6.3	11.3	-2.9	-3.1	-2.0	-1.1	-2.7	-2.4	-2.0	-2.9	-2.5	-2.3	-1.5	-3.4	-2.1	-2.2	-2.5	-3.1	-2.7	-2.6
Eye problems/disorders: None of the above	4.6	5.3	10.1	-2.8	-3.2	-2.0	-1.0	-2.1	-2.1	-1.4	-2.5	-2.5	-2.0	-1.5	-3.2	-1.4	-2.0	-2.3	-2.8	-2.8	-2.3
HDL Cholesterol	4.3	7.2	12.2	3.2	2.5	2.5	1.6	2.6	2.8	2.4	3.5	2.6	2.9	0.5	2.7	2.7	2.6	2.7	3.1	3.2	2.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.2	5.1	11.7	1.6	2.4	2.8	3.4	2.3	2.4	2.5	1.4	1.9	1.8	2.2	1.6	2.4	3.1	1.6	2.2	1.6	2.2
Qualifications: NVQ or HND or HNC or equivalent	4.2	5.1	8.6	2.9	2.5	2.4	1.1	2.1	2.1	1.0	2.8	2.7	2.3	0.8	2.8	1.8	2.0	1.8	2.8	2.9	1.9
Medication: Simvastatin	3.9	5.8	13.7	3.7	2.5	2.0	0.9	1.3	2.4	0.7	3.1	1.6	1.6	0.5	2.6	1.1	2.3	3.6	2.6	3.6	3.3
Hip circumference	3.9	16.8	24.6	-3.6	-4.5	-4.2	-4.1	-4.0	-3.8	-4.8	-4.2	-3.8	-3.2	-3.2	-4.1	-4.1	-4.5	-4.1	-5.0	-3.6	-4.5
Breastfed as a baby	3.9	4.9	8.7	-2.8	-2.4	-2.2	-2.3	-1.5	-2.1	-1.5	-2.2	-1.5	-1.1	-1.8	-2.3	-1.4	-2.3	-2.9	-2.6	-2.8	-2.8
Medication: Paracetamol	3.9	6.0	8.2	2.7	2.6	2.7	2.4	2.5	2.7	2.0	2.5	2.0	1.9	1.2	2.4	2.6	2.7	2.4	2.9	2.6	2.7
Angina	3.8	4.9	11.6	3.4	2.3	1.8	0.4	1.5	2.5	0.4	3.2	2.0	1.8	-0.6	2.6	1.5	1.8	2.6	2.6	3.3	2.4
Birth weight of first child	3.8	6.9	11.7	-3.4	-2.7	-3.2	-2.3	-2.0	-2.4	-1.7	-3.0	-2.3	-2.0	-1.8	-2.8	-1.9	-2.5	-3.0	-3.1	-3.4	-3.0
Cholesterol lowering medication	3.8	5.6	9.4	3.1	2.5	2.6	1.6	2.0	2.0	1.4	2.7	1.9	1.9	1.4	2.6	1.6	2.5	2.9	2.8	3.0	2.9
Eye problems/disorders: Glaucoma	3.7	4.4	7.9	2.7	2.7	1.3	0.4	1.6	2.4	1.2	2.8	2.3	1.9	0.1	2.7	1.8	1.7	2.1	2.4	2.7	2.2
Ever had prostate specific antigen (PSA) test	3.7	4.2	9.4	-3.1	-2.1	-1.8	-0.6	-1.7	-2.1	-0.8	-2.9	-1.9	-2.0	-0.1	-2.4	-1.4	-1.7	-2.2	-2.3	-3.1	-2.1
Worry too long after embarrassment	3.6	6.1	9.2	2.6	2.8	2.7	2.6	2.3	2.3	2.6	2.5	2.0	1.7	1.3	2.5	2.1	2.7	2.6	3.0	2.6	2.9
Medication: Ibuprofen	3.5	4.2	6.8	2.2	2.1	2.2	1.3	2.2	2.4	1.4	2.6	2.0	2.1	0.5	1.8	2.2	2.4	1.8	2.1	2.2	2.1
Medication: Lisinopril	3.5	4.6	10.7	1.3	2.1	2.3	1.7	2.3	0.9	3.0	2.1	1.9	1.5	3.3	2.2	1.9	2.0	2.3	2.7	1.2	2.4
Trunk fat mass	3.4	14.8	21.8	-3.7	-4.4	-4.2	-4.6	-3.0	-3.7	-4.0	-3.7	-3.2	-2.3	-3.4	-3.4	-3.3	-4.5	-4.4	-4.2	-3.8	-4.7
Diabetes (self-reported)	3.3	5.1	9.9	2.8	2.5	2.6	1.3	2.1	1.5	1.7	2.5	1.9	1.7	1.3	2.8	1.3	2.1	2.7	3.1	2.8	2.7
Mother’s age at death	3.3	4.2	7.0	-2.5	-2.5	-1.5	-2.2	-1.5	-2.6	-2.0	-2.0	-1.6	-1.4	-1.2	-2.0	-1.9	-2.1	-2.4	-1.8	-2.4	-2.6
Age when periods started (menarche)	3.2	7.7	17.4	-3.8	-3.1	-1.5	-2.4	-0.8	-3.5	-1.8	-3.3	-1.9	-1.2	-1.1	-2.7	-2.2	-2.8	-4.2	-2.5	-3.8	-3.9
Alcohol usually taken with meals	3.2	5.1	8.9	-2.6	-2.5	-2.4	-1.7	-2.2	-2.3	-1.8	-2.5	-2.2	-1.9	-1.0	-2.7	-2.3	-2.2	-2.1	-3.0	-2.5	-2.3
Angina (self-reported)	3.2	4.2	10.4	3.2	2.1	1.4	0.0	1.2	2.3	0.1	3.1	1.8	1.7	-0.9	2.4	1.4	1.6	2.5	2.3	3.1	2.3
Blood Eosinophil Count	3.1	23.6	35.9	4.4	5.2	4.3	2.9	5.0	5.1	4.6	6.0	5.8	5.6	2.8	5.0	6.0	5.1	3.9	5.3	4.4	4.5
Diverticular disease/diverticulitis (self-reported)	3.1	3.7	7.5	-2.5	-2.3	-1.7	-2.1	-0.8	-2.2	-1.3	-2.1	-1.2	-0.8	-0.4	-1.5	-1.3	-2.3	-2.7	-1.6	-2.5	-2.7
Weight	3.0	14.6	20.2	-3.4	-4.3	-3.8	-4.0	-3.3	-3.8	-4.5	-3.8	-3.4	-2.7	-3.1	-3.6	-3.8	-4.2	-4.2	-4.3	-3.5	-4.5
Exposure to tobacco smoke outside home	3.0	4.0	6.7	1.8	2.4	1.6	2.0	2.6	2.1	2.1	1.4	2.2	2.3	1.9	2.6	2.0	1.9	1.0	2.3	1.8	1.4
Trunk fat percentage	2.9	11.5	19.5	-3.4	-3.8	-3.9	-4.4	-2.4	-3.3	-3.2	-3.2	-2.6	-1.8	-3.0	-2.7	-2.6	-4.2	-4.1	-3.6	-3.4	-4.2
Mouth/teeth dental problems	2.8	4.3	10.5	-3.2	-2.0	-1.0	-0.1	-1.9	-2.3	-0.8	-2.8	-2.1	-2.2	0.3	-3.0	-1.6	-1.0	-1.6	-2.6	-3.2	-1.6
Forced vital capacity (FVC), Best measure	2.8	10.3	16.2	-4.0	-3.6	-2.8	-2.4	-2.5	-4.0	-1.7	-3.7	-3.2	-3.0	-1.4	-3.2	-3.0	-3.8	-3.3	-3.3	-3.9	-3.5
Bipolar Disorder (2011)	2.7	2.6	5.0	1.7	2.2	0.8	1.6	1.1	2.2	1.7	1.3	1.8	1.1	1.5	2.1	1.6	1.2	1.2	1.7	1.7	1.4
Primary Biliary Cirrhosis	2.7	3.9	10.5	-0.2	-2.0	-1.4	-1.5	-2.6	-2.0	-2.4	-1.4	-2.9	-2.8	-2.4	-1.6	-3.2	-2.2	0.2	-1.6	-0.2	-0.5
Forced vital capacity (FVC)	2.7	10.6	18.1	-4.0	-3.6	-2.6	-2.7	-2.4	-4.2	-1.9	-3.7	-2.8	-2.6	-1.0	-3.0	-3.1	-4.1	-3.8	-3.2	-3.9	-3.9
Leg fat-free mass (right)	2.7	14.5	21.7	-3.1	-4.4	-3.2	-3.2	-3.7	-4.1	-4.7	-4.0	-4.1	-3.5	-3.1	-4.0	-4.5	-3.9	-3.2	-4.3	-3.1	-3.8
Leg predicted mass (right)	2.7	14.5	21.7	-3.1	-4.4	-3.2	-3.2	-3.7	-4.1	-4.7	-4.0	-4.1	-3.5	-3.1	-4.0	-4.5	-3.9	-3.2	-4.3	-3.1	-3.8
Medication: Metformin	2.6	3.6	6.4	2.5	2.1	2.2	1.1	1.6	1.3	1.2	2.3	1.9	1.5	1.2	2.3	1.0	1.9	2.1	2.5	2.4	2.1
Pack years adult smoking proportion	2.6	4.0	6.8	2.0	2.0	2.6	1.8	2.2	1.7	1.2	1.8	1.8	2.0	2.2	1.9	1.6	2.4	1.8	2.2	2.0	2.0
Glaucoma (self-reported)	2.6	3.1	7.2	2.7	2.1	0.9	-0.1	0.9	1.9	0.3	2.6	1.8	1.5	-0.8	2.2	1.3	1.2	2.0	1.8	2.7	1.8
Number of full brothers	2.5	3.2	6.4	2.0	1.9	1.6	1.2	2.0	2.5	0.7	1.8	2.3	2.4	0.3	2.0	2.3	1.6	0.5	2.0	2.0	0.9
Miserableness	2.5	4.3	7.4	1.6	2.2	2.5	2.3	2.5	2.3	2.0	1.6	2.1	2.3	1.3	1.8	2.5	2.7	1.2	2.2	1.6	1.8
Basal metabolic rate	2.5	13.6	20.0	-3.2	-4.2	-3.3	-3.4	-3.4	-3.9	-4.5	-3.8	-3.7	-3.0	-3.0	-3.8	-4.1	-3.8	-3.5	-4.2	-3.2	-4.0
Leg fat-free mass (left)	2.4	12.8	19.1	-3.0	-4.1	-3.1	-3.1	-3.4	-3.8	-4.4	-3.7	-3.7	-3.0	-2.9	-3.7	-4.0	-3.7	-3.3	-4.1	-3.0	-3.8
Leg predicted mass (left)	2.4	12.7	19.4	-2.9	-4.1	-3.1	-3.1	-3.5	-3.8	-4.4	-3.7	-3.8	-3.1	-2.9	-3.7	-4.1	-3.7	-3.2	-4.1	-2.9	-3.6
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.0	5.7	1.9	1.8	1.6	1.1	1.9	2.4	1.0	2.2	1.9	2.0	0.4	1.5	1.9	2.0	1.3	1.6	1.9	1.6
Smoking status: Previous	2.4	3.5	6.7	-2.4	-2.0	-1.7	-1.9	-1.1	-2.1	-1.6	-2.0	-1.3	-1.2	-1.0	-1.6	-1.4	-1.9	-2.6	-1.8	-2.5	-2.6
Whole body fat-free mass	2.4	13.6	20.7	-3.1	-4.2	-3.2	-3.2	-3.6	-3.9	-4.5	-3.7	-3.8	-3.2	-3.0	-3.9	-4.2	-3.7	-3.3	-4.3	-3.1	-3.8
Gout (self-reported)	2.3	3.2	4.3	1.9	2.0	1.2	1.0	1.7	2.0	1.5	2.1	1.9	1.9	1.6	1.9	1.7	1.9	1.8	1.8	1.9	2.0
Diabetes diagnosed by doctor	2.3	3.8	8.3	2.5	2.1	2.4	1.2	1.8	1.0	1.3	2.1	1.5	1.3	1.0	2.5	0.8	1.7	2.3	2.9	2.5	2.2
Whole body water mass	2.3	13.4	20.3	-3.1	-4.2	-3.2	-3.2	-3.5	-3.8	-4.5	-3.7	-3.8	-3.2	-2.9	-3.9	-4.2	-3.7	-3.3	-4.3	-3.1	-3.8
Reaction Time	2.2	4.2	7.5	1.5	2.7	1.2	2.2	2.0	2.7	2.4	1.5	2.5	2.4	2.5	2.0	2.5	2.1	1.0	1.5	1.5	1.6
Other serious medical condition/disability diagnosed by doctor	2.2	2.8	4.5	-1.8	-1.9	-1.2	-0.8	-1.5	-1.5	-2.0	-2.1	-1.5	-1.3	-1.3	-2.1	-1.6	-1.1	-1.9	-2.1	-1.8	-2.0
Chronic bronchitis/emphysema (father)	2.2	2.6	3.8	-1.8	-1.8	-1.8	-1.9	-1.3	-1.9	-1.0	-1.5	-1.6	-1.5	-1.0	-1.3	-1.5	-2.0	-1.3	-1.6	-1.8	-1.5
Trunk predicted mass	2.2	12.3	17.6	-3.1	-4.0	-3.1	-3.1	-3.4	-3.6	-4.2	-3.5	-3.6	-3.1	-2.9	-3.8	-3.9	-3.5	-3.2	-4.1	-3.1	-3.6
Whole body fat mass	2.2	9.2	13.5	-2.8	-3.5	-3.1	-3.6	-2.3	-3.0	-3.4	-2.9	-2.5	-1.8	-2.8	-2.7	-2.7	-3.4	-3.5	-3.3	-2.8	-3.7
Overall health rating	2.2	4.7	7.2	2.7	2.2	2.0	1.5	2.0	2.4	1.4	2.4	1.9	2.1	1.1	2.4	2.1	2.2	2.2	2.5	2.6	2.4
Ever depressed for a whole week	2.2	2.7	5.9	1.9	1.9	1.6	1.5	1.6	1.4	1.5	1.4	1.1	0.7	0.9	2.1	1.0	1.4	1.9	2.4	1.9	1.9
Bipolar Disorder (2018)	2.1	3.4	7.9	2.0	2.1	1.1	0.9	2.0	2.2	1.0	1.7	2.8	2.4	1.5	2.7	2.0	1.0	0.0	2.1	2.0	0.4
Trunk fat-free mass	2.1	11.8	17.1	-3.0	-3.9	-3.0	-3.0	-3.3	-3.6	-4.1	-3.4	-3.6	-3.0	-2.8	-3.8	-3.9	-3.4	-3.1	-4.0	-3.0	-3.5
Prospective memory result	2.1	2.6	4.5	-2.1	-1.4	-1.4	-1.2	-1.4	-1.9	-0.9	-2.0	-1.1	-1.3	-0.1	-1.6	-1.5	-1.6	-2.0	-1.9	-2.1	-1.9
Depression (Nagel 2018)	2.0	3.0	7.9	-2.7	-1.7	-0.9	0.3	-0.9	-1.5	-0.5	-2.8	-1.7	-1.3	-0.2	-2.3	-1.0	-0.8	-2.2	-2.1	-2.7	-1.9
Stomach or abdominal pain in last month	2.0	2.5	4.6	1.0	1.4	2.1	1.9	2.1	1.7	1.3	1.1	1.7	1.6	1.3	1.4	2.2	2.1	0.4	2.0	0.9	0.8
Number of incorrect matches in round	2.0	3.4	9.5	-3.1	-1.9	-1.2	-0.6	-1.2	-2.2	0.0	-2.5	-1.7	-1.6	0.2	-2.3	-1.2	-1.3	-1.9	-2.0	-3.1	-1.7
Falls in the last year	2.0	2.7	4.7	-2.2	-2.1	-0.7	-0.6	-1.0	-1.9	-0.7	-2.1	-1.9	-1.7	-1.5	-1.9	-1.3	-1.4	-1.8	-1.2	-2.2	-1.8
Illnesses of father: Heart disease	2.0	2.7	6.1	2.5	1.6	1.3	0.3	1.2	1.2	0.8	2.2	1.3	0.9	0.6	2.3	0.9	0.8	2.2	2.5	2.4	2.0
Eye problems/disorders: Cataract	2.0	2.3	8.1	1.3	2.1	1.3	1.5	1.5	1.4	1.3	0.7	1.8	1.4	2.8	2.0	0.9	1.2	0.6	1.5	1.3	0.9
Arm predicted mass (left)	2.0	10.0	14.3	-2.9	-3.6	-3.0	-2.9	-2.8	-3.3	-3.8	-3.2	-3.0	-2.4	-2.2	-3.3	-3.3	-3.2	-3.3	-3.8	-2.9	-3.5
Ulcerative Colitis	1.9	2.7	6.6	-2.1	-2.0	-0.6	-0.3	-1.3	-2.0	-1.0	-2.0	-2.0	-1.6	-0.8	-2.6	-1.5	-0.9	-1.3	-2.1	-2.2	-1.3
Sitting height	1.9	13.2	21.6	-4.3	-4.2	-3.1	-3.2	-2.3	-4.7	-2.6	-4.1	-3.1	-2.5	-1.5	-3.3	-3.5	-4.2	-4.5	-3.6	-4.3	-4.6
Past tobacco smoking	1.9	3.4	7.3	2.7	1.9	1.9	1.4	1.1	1.7	0.9	2.3	1.4	1.2	0.5	1.8	1.1	1.8	2.5	2.1	2.7	2.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.2	11.1	-2.6	-2.7	-2.0	-1.7	-2.4	-3.3	-1.6	-2.8	-2.9	-2.8	-1.2	-2.5	-2.9	-3.0	-1.8	-2.6	-2.6	-2.2
Alcohol intake frequency.	1.9	4.5	11.2	-2.6	-2.1	-1.4	-0.1	-2.0	-2.2	-1.4	-3.4	-2.2	-2.0	0.0	-2.6	-2.1	-1.6	-2.2	-2.6	-2.6	-2.1
Ever smoked	1.9	3.3	8.3	-2.9	-2.0	-1.2	-0.4	-1.1	-1.7	-0.6	-2.6	-1.6	-1.3	-0.2	-2.4	-0.9	-1.3	-2.3	-2.2	-2.9	-2.1
Alzheimer’s Disease (in mother)	1.8	2.1	4.6	-1.1	-1.8	-1.3	-0.8	-1.7	-1.0	-1.8	-1.2	-1.7	-1.6	-2.2	-1.9	-1.4	-1.1	-0.9	-1.7	-1.1	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.9	6.8	-1.4	-2.0	-2.3	-1.8	-2.5	-2.2	-1.7	-1.8	-2.3	-2.5	-1.7	-1.6	-2.4	-2.6	-0.9	-2.0	-1.4	-1.5
Arm fat-free mass (left)	1.8	9.0	13.4	-2.7	-3.3	-2.8	-2.9	-2.7	-3.1	-3.7	-3.0	-2.8	-2.3	-2.2	-3.1	-3.2	-3.1	-3.0	-3.6	-2.7	-3.3
Pain all over the body in last month	1.7	1.8	2.9	1.1	1.7	1.1	1.6	1.2	1.4	1.6	1.0	1.0	0.9	1.2	1.3	1.4	1.7	1.6	1.3	1.1	1.7
Hayfever/allergic rhinitis (self-reported)	1.7	2.2	5.1	-0.8	-1.6	-0.5	-1.0	-1.6	-1.6	-2.3	-1.4	-1.7	-1.7	-2.1	-1.6	-2.1	-1.2	-0.9	-1.3	-0.8	-1.3
Forced expiratory volume in 1-second (FEV1)	1.7	5.9	12.1	-2.7	-2.5	-1.8	-1.9	-2.1	-3.5	-1.5	-2.8	-2.5	-2.5	-0.7	-2.2	-2.9	-3.1	-2.1	-2.3	-2.6	-2.5
Arm fat-free mass (right)	1.7	8.6	15.9	-2.2	-3.3	-2.7	-2.9	-2.9	-2.9	-4.0	-2.6	-2.9	-2.4	-2.7	-3.0	-3.4	-3.0	-2.5	-3.5	-2.2	-3.0
Medication: Gliclazide	1.7	1.9	3.9	2.0	1.5	1.6	0.8	0.9	1.3	0.7	1.8	1.1	1.0	0.9	1.3	0.9	1.4	1.8	1.4	1.8	1.9
Ulcerative Colitis (UC)	1.6	3.0	6.2	-2.2	-2.0	-0.7	-0.2	-1.3	-2.1	-0.9	-2.3	-2.2	-1.7	-0.6	-2.5	-1.7	-1.1	-1.5	-2.3	-2.3	-1.4
HbA1C	1.6	1.8	3.0	1.7	1.4	1.0	1.0	0.9	1.7	0.8	1.7	1.1	1.0	0.8	1.3	1.1	1.3	1.7	1.4	1.7	1.7
Smoking Status	1.6	3.9	9.5	-3.1	-2.1	-2.1	-0.9	-1.3	-1.8	-0.4	-2.7	-1.4	-1.4	0.3	-1.9	-0.9	-2.0	-2.7	-2.1	-3.1	-2.5
Impedance of arm (right)	1.6	7.6	16.1	-4.0	-3.1	-2.8	-3.3	-1.1	-3.6	-0.2	-2.8	-1.9	-1.4	-1.5	-2.0	-1.5	-3.5	-3.5	-2.1	-3.9	-3.5
Mouth/teeth dental problems: Dentures	1.6	2.7	8.8	3.0	1.4	1.4	0.4	1.0	2.1	-0.8	2.2	1.6	1.7	-0.7	1.8	0.9	1.3	1.2	1.5	2.9	1.1
Arm fat mass (right)	1.6	6.5	10.0	-2.1	-2.8	-2.7	-3.0	-2.2	-2.4	-3.2	-2.4	-2.2	-1.7	-2.3	-2.2	-2.4	-2.9	-2.6	-2.9	-2.2	-2.9
Pack years of smoking	1.6	2.3	5.0	1.6	1.5	2.2	1.4	1.8	1.2	0.6	1.3	1.3	1.5	1.6	1.4	1.1	1.9	1.3	1.7	1.5	1.4
Irritable Bowel Disease (IBD)	1.5	3.6	7.2	-2.2	-2.3	-0.6	-0.2	-1.4	-2.2	-1.4	-2.6	-2.5	-1.9	-0.8	-2.7	-2.0	-1.2	-1.6	-2.4	-2.3	-1.6
Hayfever, allergic rhinitis or eczema	1.5	3.2	5.3	-1.8	-1.9	-1.8	-1.3	-1.8	-1.7	-1.6	-2.0	-1.8	-1.6	-1.0	-2.0	-1.9	-2.0	-1.7	-2.3	-1.8	-1.8
Wheeze or whistling in the chest in last year	1.5	2.7	5.5	1.0	1.7	1.3	1.9	2.0	2.0	2.1	1.3	1.8	2.0	1.2	1.5	2.3	1.9	0.7	1.5	1.0	1.3
Arm predicted mass (right)	1.5	7.5	13.5	-2.0	-3.0	-2.8	-2.7	-2.7	-2.6	-3.7	-2.5	-2.8	-2.2	-2.6	-2.9	-3.1	-2.7	-2.3	-3.4	-2.1	-2.7
Average weekly red wine intake	1.5	2.3	4.2	-1.2	-1.8	-1.2	-1.0	-1.8	-1.4	-1.9	-1.5	-1.6	-1.3	-1.3	-2.0	-1.5	-1.3	-1.2	-2.0	-1.2	-1.3
Arm fat mass (left)	1.5	6.3	9.4	-2.0	-2.8	-2.7	-3.1	-2.1	-2.5	-3.0	-2.4	-2.2	-1.7	-2.3	-2.1	-2.5	-2.9	-2.6	-2.8	-2.1	-2.8
Wears glasses or contact lenses	1.5	1.7	5.8	-0.0	-0.9	-1.1	-1.5	-1.9	-0.7	-2.4	-0.3	-1.3	-1.4	-2.4	-1.2	-1.7	-0.6	0.3	-1.3	-0.0	-0.3
Vascular/heart problems diagnosed by doctor	1.5	4.1	11.0	-2.8	-1.9	-1.9	-0.7	-1.1	-1.7	-1.1	-2.8	-1.2	-1.1	-0.2	-1.9	-1.2	-1.9	-3.3	-2.3	-2.7	-3.1
Hearing difficulty/problems: Yes	1.4	2.1	5.7	2.4	1.0	1.5	1.5	-0.3	1.6	-1.3	1.2	-0.2	-0.4	-1.2	0.5	0.0	1.8	2.4	1.1	2.3	1.9
Multivitamins +/- minerals	1.4	1.7	3.2	-1.7	-1.6	0.3	-0.2	-0.5	-1.6	-1.0	-1.7	-1.2	-1.1	-1.1	-1.7	-1.1	-0.6	-1.8	-1.0	-1.8	-1.7
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	6.5	-2.1	-1.6	-0.1	0.4	-0.8	-1.3	-0.9	-2.2	-1.7	-1.1	-0.6	-2.5	-0.8	0.0	-1.4	-2.0	-2.2	-1.2
Impedance of arm (left)	1.4	6.6	13.0	-3.6	-2.9	-2.7	-3.3	-1.0	-3.4	-0.2	-2.4	-1.9	-1.3	-2.0	-1.8	-1.5	-3.4	-3.1	-1.9	-3.5	-3.1
Headache pain in last month	1.4	2.4	4.3	1.6	1.9	1.6	1.7	1.7	1.9	1.2	1.4	1.5	1.3	0.7	1.4	1.3	2.1	1.3	1.5	1.6	1.6
Body fat percentage	1.4	5.3	10.3	-2.3	-2.6	-2.6	-3.2	-1.4	-2.1	-2.3	-2.2	-1.5	-0.8	-2.0	-1.6	-1.6	-2.9	-3.1	-2.4	-2.3	-3.1
Qualifications: College or University degree	1.4	4.3	6.6	-1.7	-2.4	-2.0	-2.5	-1.8	-2.4	-2.3	-1.8	-2.1	-1.7	-2.2	-1.8	-2.6	-2.4	-1.7	-1.8	-1.6	-2.1
Guilty feelings	1.4	2.1	3.3	1.5	1.5	1.7	1.1	1.7	1.7	1.0	1.5	1.4	1.6	0.2	1.4	1.6	1.8	1.1	1.7	1.4	1.3
Fractured/broken bones in last 5 years	1.4	1.8	3.6	-1.3	-1.2	-1.9	-1.1	-1.6	-0.8	-1.2	-1.3	-1.5	-1.3	-1.6	-1.6	-1.1	-1.4	-0.9	-1.9	-1.3	-1.1
Body Mass Index (BMI) (2010)	1.3	1.7	4.5	-1.6	-1.4	-1.1	-0.3	-1.4	-0.9	-1.3	-1.7	-1.6	-1.2	-0.1	-2.0	-1.0	-0.7	-0.9	-2.1	-1.6	-0.9
Allergy or Eczema	1.3	3.5	5.9	-2.1	-1.9	-1.6	-1.3	-1.8	-2.0	-1.9	-2.2	-1.6	-1.4	-0.6	-2.1	-1.9	-1.7	-2.0	-2.4	-2.1	-2.1
Hearing difficulty/problems with background noise	1.3	2.1	5.6	1.9	1.2	1.9	2.3	0.5	2.1	-0.1	1.2	0.4	0.3	-0.6	0.4	1.1	2.4	1.9	1.1	1.8	1.8
Medication: Ramipril	1.3	1.6	7.0	0.6	-1.0	-0.7	-1.5	-1.7	-0.4	-2.3	0.1	-1.5	-1.1	-2.6	-1.2	-1.5	-0.6	0.7	-1.2	0.6	0.2
Noisy workplace	1.3	1.6	3.1	1.4	1.2	0.7	0.1	1.5	1.3	1.2	1.8	1.4	1.5	0.1	1.7	1.6	0.8	0.9	1.6	1.3	1.0
Neck or shoulder pain in last month	1.3	1.8	3.2	1.3	1.3	1.8	1.1	1.4	0.8	1.5	1.3	1.3	1.2	1.8	1.3	1.1	1.4	1.3	1.6	1.2	1.5
Hypertension (Self-reported)	1.3	3.7	11.1	2.4	1.8	1.9	1.1	1.0	1.6	1.5	2.5	1.0	0.9	0.7	1.6	1.3	1.9	3.3	2.1	2.3	3.1
Number of self-reported non-cancer illnesses	1.3	2.2	3.9	1.7	1.3	2.0	1.1	1.7	1.1	0.9	1.5	0.9	1.3	0.4	1.5	1.2	1.8	1.8	1.9	1.7	1.8
Risk taking	1.3	2.0	5.6	-2.4	-1.3	-0.9	0.1	-0.3	-1.1	0.4	-2.2	-1.1	-0.6	0.2	-1.7	-0.5	-1.0	-2.1	-1.6	-2.4	-1.6
Myopia	1.3	1.8	6.9	-0.6	-1.3	-1.6	-1.6	-1.6	-0.5	-2.3	-0.6	-1.3	-1.1	-2.6	-1.5	-1.0	-0.6	-0.6	-1.6	-0.6	-0.9
High blood pressure	1.2	3.3	10.9	2.4	1.5	1.9	0.8	0.9	1.4	1.2	2.5	0.8	0.7	0.4	1.5	1.1	1.7	3.3	2.1	2.3	3.0
Waist circumference	1.2	4.5	10.3	-1.1	-2.3	-2.3	-2.7	-2.3	-1.6	-3.2	-1.7	-1.9	-1.6	-2.4	-1.8	-2.2	-2.3	-1.8	-2.4	-1.2	-2.1
Financial difficulties in last 2 years	1.2	1.6	4.8	0.1	1.1	1.7	1.3	2.2	1.0	1.5	0.5	1.6	1.9	0.9	0.8	1.9	1.6	-0.6	1.1	0.1	0.1
Neuroticism score	1.2	2.5	5.1	1.0	1.7	1.8	1.3	2.0	1.7	1.5	1.5	2.1	2.1	1.0	1.3	2.3	2.0	0.5	1.5	1.0	1.0
Worrier / anxious feelings	1.2	2.2	4.7	0.7	1.6	1.5	1.7	1.7	1.4	2.2	1.2	1.5	1.5	1.5	1.2	2.0	1.9	1.0	1.4	0.8	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	5.2	-1.8	-1.7	-0.8	-0.1	-1.2	-0.9	-0.9	-1.9	-1.7	-1.3	-1.3	-2.3	-0.7	-0.4	-1.3	-1.9	-1.9	-1.2
Happiness	1.2	1.4	2.7	1.6	1.0	1.6	1.0	1.2	1.4	0.4	1.2	1.0	1.1	-0.5	1.1	1.0	1.2	0.9	1.5	1.6	1.0
Blood clot in the leg (DVT)	1.2	1.6	5.0	0.8	1.1	1.8	2.2	1.6	0.9	1.6	0.5	0.8	0.9	1.2	1.0	1.1	1.6	0.9	1.5	0.8	1.1
Handedness (chirality/laterality): Left-handed	1.2	1.5	2.8	0.8	1.3	1.2	1.1	1.2	1.2	1.4	1.1	1.5	1.2	1.3	1.3	1.7	1.2	0.6	1.4	0.8	0.9
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	4.2	0.8	1.1	1.7	2.0	1.6	0.9	1.5	0.6	0.9	1.0	1.1	1.1	1.0	1.6	0.8	1.5	0.8	1.0
Bipolar Disorder or Schizophrenia	1.1	2.7	6.5	1.8	2.2	0.3	0.6	1.6	2.2	1.0	1.6	2.5	2.2	1.4	2.5	1.9	0.8	0.3	1.6	1.8	0.6
Breast Cancer	1.1	2.6	6.2	-2.1	-1.8	-0.6	-1.2	-1.0	-1.9	-1.6	-1.8	-0.9	-0.8	-0.9	-1.9	-1.0	-1.1	-2.5	-1.7	-2.2	-2.4
Neuroticism (2016)	1.1	1.6	4.4	0.5	1.1	1.5	1.1	2.1	1.3	1.7	1.1	1.0	1.6	0.2	0.8	1.7	1.8	0.8	1.3	0.5	1.2
Mean time to correctly identify matches	1.1	2.2	4.2	0.9	1.9	0.7	1.5	1.3	2.0	1.4	1.0	2.1	1.9	2.0	1.4	2.0	1.6	0.3	0.8	0.9	0.8
Comparative height size at age 10	1.1	6.3	9.1	-1.9	-2.6	-3.0	-3.0	-2.5	-2.4	-2.8	-2.0	-2.3	-2.3	-2.7	-2.1	-2.8	-3.0	-2.1	-2.6	-1.9	-2.6
Alzheimer’s Disease (in father)	1.0	1.1	3.8	-0.4	-0.5	-0.8	-0.5	-1.7	-1.1	-0.6	-0.8	-1.5	-1.9	-1.4	-1.0	-1.7	-0.8	0.6	-1.1	-0.4	0.1
Maternal smoking around birth	1.0	1.4	4.2	0.3	0.8	0.9	0.1	2.1	0.9	1.0	1.1	1.8	2.0	0.6	1.4	1.9	0.9	-0.6	1.4	0.4	-0.2
Peak expiratory flow (PEF)	1.0	2.3	6.2	-1.7	-1.9	-0.2	-0.8	-1.0	-2.5	-1.0	-1.7	-1.9	-1.8	-0.6	-1.8	-2.0	-1.3	-1.0	-1.2	-1.8	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	3.1	-1.7	-1.8	-1.0	-1.1	-0.7	-1.5	-1.3	-1.5	-1.4	-1.0	-1.5	-1.6	-1.0	-1.1	-1.7	-1.4	-1.8	-1.7
Alcohol drinker status: Never	1.0	1.2	3.5	-1.6	-0.7	-1.2	0.2	-0.9	-0.7	0.3	-1.9	-0.8	-0.6	1.3	-1.1	-0.4	-0.9	-1.2	-1.7	-1.5	-0.9
Vitamin and mineral supplements	0.9	1.2	3.1	1.4	1.4	-0.7	-0.4	0.3	1.2	1.0	1.4	1.0	0.8	1.1	1.8	0.8	0.2	1.5	0.9	1.4	1.4
Townsend deprivation index at recruitment	0.9	1.3	4.4	0.3	0.6	1.9	1.9	1.3	1.0	1.5	0.7	0.3	0.7	-0.2	-0.2	1.5	2.1	1.0	0.9	0.3	1.3
Serious illness, injury or assault to yourself	0.9	1.1	2.0	0.8	0.9	0.9	1.0	1.2	1.2	1.4	1.0	0.9	0.7	0.9	1.0	1.3	1.1	0.9	1.3	0.7	1.1
Arm fat percentage (right)	0.9	3.4	5.8	-1.7	-2.1	-2.0	-2.4	-1.3	-1.8	-2.0	-1.8	-1.4	-0.9	-1.6	-1.5	-1.4	-2.2	-2.3	-2.0	-1.8	-2.4
Medication: Allopurinol	0.9	1.3	2.3	0.7	1.2	0.4	0.3	1.4	1.1	1.2	1.3	1.5	1.4	1.4	1.5	1.3	1.0	0.6	1.3	0.7	0.8
Heart disease (mother)	0.9	1.1	1.9	1.0	1.1	0.9	1.1	1.2	1.2	1.0	1.0	1.1	1.4	1.0	1.0	1.2	1.0	0.6	0.8	1.0	0.8
Medication: Aspirin	0.9	1.2	4.4	1.6	1.2	0.6	0.5	0.4	0.8	0.7	1.3	0.3	0.3	0.4	1.1	0.1	0.8	2.1	1.1	1.5	1.9
Arm fat percentage (left)	0.9	3.4	6.2	-1.5	-2.1	-2.0	-2.5	-1.4	-1.7	-2.1	-1.7	-1.5	-0.9	-1.9	-1.4	-1.5	-2.2	-2.1	-2.0	-1.6	-2.2
Mood swings	0.9	1.5	4.1	0.5	1.0	1.9	1.3	1.9	1.1	1.0	0.6	1.6	2.0	1.1	0.6	1.7	1.6	-0.4	0.9	0.4	0.3
Friendships satisfaction	0.9	1.1	2.6	1.3	1.1	1.6	1.2	0.6	0.7	0.7	0.9	0.6	0.5	0.6	0.8	0.4	1.2	1.5	1.1	1.2	1.5
Leg fat mass (left)	0.9	3.5	6.9	-1.6	-2.1	-1.8	-2.3	-1.2	-1.6	-2.6	-1.8	-1.2	-0.6	-1.5	-1.6	-1.5	-2.0	-2.6	-2.2	-1.7	-2.6
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.7	1.8	1.0	1.8	0.9	0.6	0.3	0.6	1.3	0.2	-0.0	-0.1	1.1	0.0	1.2	2.2	1.7	1.7	1.9
Average weekly fortified wine intake	0.8	1.0	3.3	-0.8	-0.7	-0.1	0.4	-1.1	-0.9	-0.7	-1.2	-1.6	-1.8	-1.1	-1.3	-1.4	-0.1	0.2	-0.7	-0.8	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	4.7	-1.6	-1.9	-0.4	-1.6	-0.4	-2.2	-1.0	-1.0	-0.9	-0.7	-1.0	-1.2	-1.1	-1.4	-1.7	-0.7	-1.6	-1.7
Medication: Atenolol	0.8	1.0	2.2	1.5	1.4	0.7	-0.3	0.5	0.7	0.4	1.4	0.9	0.6	-0.3	1.5	0.2	0.5	1.4	1.3	1.5	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	5.2	-1.8	-1.9	-0.6	-1.3	-0.9	-2.3	-0.9	-1.4	-1.3	-1.3	-0.5	-1.3	-1.3	-1.5	-1.3	-0.9	-1.8	-1.5
Health satisfaction	0.8	1.1	3.9	2.0	0.4	-0.4	-0.2	-0.9	1.5	-1.0	1.1	-0.2	-0.4	-0.8	0.6	-0.2	0.2	1.7	0.2	1.9	1.3
Medication: Blood pressure	0.8	1.5	5.0	1.7	1.0	1.4	1.1	0.2	1.2	0.3	1.5	0.2	0.1	-0.5	0.6	0.5	1.4	2.2	1.1	1.7	2.0
Medication: Seretide 50 evohaler	0.8	1.0	4.2	1.2	-0.1	-0.7	-1.4	-0.8	0.6	-1.5	1.3	-0.3	-0.3	-2.0	0.1	-0.2	0.1	1.3	-0.1	1.3	0.8
Leg fat mass (right)	0.8	2.9	6.5	-1.4	-1.8	-1.7	-2.1	-1.0	-1.4	-2.3	-1.7	-0.9	-0.4	-1.3	-1.3	-1.3	-1.9	-2.6	-1.9	-1.5	-2.5
Alcohol drinker status: Previous	0.8	0.9	2.2	-1.2	-1.0	-0.6	0.1	-0.7	-0.8	-0.8	-1.5	-1.1	-0.9	-1.1	-1.2	-0.9	-0.5	-1.0	-0.9	-1.2	-1.0
Neuroticism (Nagel 2018)	0.7	1.6	3.6	-0.0	1.2	1.5	1.9	1.7	1.3	1.9	0.2	1.4	1.4	1.8	0.6	1.8	1.5	-0.4	0.9	-0.1	0.3
Schizophrenia vs Biploar Disorder	0.7	1.0	1.9	-0.8	-1.0	-0.9	-1.2	-1.3	-1.2	-1.1	-0.6	-1.2	-1.1	-0.6	-1.3	-1.2	-0.6	0.1	-1.4	-0.8	-0.2
Worry (Nagel 2018)	0.7	1.4	4.3	-0.3	1.0	1.1	1.8	1.1	1.1	1.8	0.0	1.2	1.2	2.1	0.2	1.9	1.4	-0.3	0.3	-0.3	0.3
Major Depression (MDD)	0.7	0.9	2.3	-1.1	-0.9	-1.3	0.1	-1.1	-0.5	0.4	-1.3	-1.5	-1.5	-0.3	-1.0	-0.7	-0.9	-0.1	-1.0	-1.1	-0.1
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.5	0.8	-0.6	-0.9	-1.0	-2.1	-0.5	-2.1	0.1	-1.6	-1.9	-1.6	-0.7	-2.0	-0.7	1.5	-0.6	0.9	0.6
Lupus	0.7	1.1	4.5	0.8	-0.2	-0.6	0.2	-1.4	-0.0	-0.0	0.5	-1.3	-2.1	-1.5	-0.2	-1.0	-0.2	2.1	0.2	0.8	1.4
Rheumatoid Arthritis	0.7	1.0	4.3	-0.2	-0.6	-1.1	-1.2	-1.4	-0.5	-1.1	-0.3	-1.1	-1.3	-2.1	-0.7	-1.3	-1.0	0.2	-0.8	-0.2	-0.2
Medication for hormone replacement therapy	0.7	0.8	2.5	-1.6	-0.4	-0.5	-0.0	0.5	-0.4	0.1	-0.8	0.5	0.7	1.5	-0.6	0.5	0.1	-1.6	-0.8	-1.5	-1.2
Relative age voice broke	0.7	1.1	2.3	1.3	1.5	0.3	0.8	0.7	1.4	1.0	0.7	0.8	0.6	1.2	1.4	0.6	0.9	1.3	0.9	1.3	1.4
Qualifications: CSEs or equivalent	0.7	1.0	2.7	0.5	1.3	0.3	0.3	1.6	1.1	1.4	0.7	1.3	1.4	0.7	1.4	1.2	0.7	-0.0	1.0	0.5	0.4
Supplements: Glucosamine	0.7	1.0	3.3	-0.9	-0.9	-0.6	-1.2	-0.4	-1.2	-1.0	-1.0	-0.1	-0.4	-0.4	-0.2	-0.9	-1.4	-1.7	-0.4	-0.8	-1.8
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.5	-0.2	1.0	1.1	1.5	1.4	0.5	1.6	-0.1	0.8	0.6	1.4	0.7	1.0	0.9	-0.2	1.0	-0.2	0.3
Number of live births	0.7	0.9	2.5	1.5	0.6	0.4	0.2	-0.0	1.6	-0.2	1.6	0.6	0.5	-1.0	0.4	1.1	0.9	1.3	0.5	1.4	1.1
Age at first live birth	0.7	1.3	2.8	-1.1	-1.5	-1.0	-1.6	-1.1	-1.7	-0.5	-0.7	-1.2	-1.1	-1.2	-1.0	-1.1	-1.6	-0.6	-0.9	-1.1	-0.8
Illnesses of siblings: Diabetes	0.7	0.9	3.0	0.1	-0.6	-1.2	-1.4	-1.2	-0.7	-1.7	-0.4	-0.9	-0.9	-1.1	-0.4	-1.5	-1.0	-0.1	-0.8	0.1	-0.5
Ever had bowel cancer screening	0.7	0.9	2.7	-1.6	-1.1	-0.5	-0.6	0.0	-1.0	0.1	-1.2	-0.4	0.0	0.3	-0.9	0.1	-0.8	-1.5	-0.8	-1.6	-1.2
Back pain experienced in last month	0.7	1.1	2.5	-1.6	-1.1	-0.4	-0.2	-0.6	-1.6	-0.0	-1.4	-1.4	-1.4	-0.2	-1.2	-1.2	-0.6	-0.6	-0.7	-1.6	-0.6
Breast cancer (self-reported)	0.7	0.9	2.2	1.3	0.8	0.6	-0.5	0.8	0.9	0.3	1.5	1.3	1.5	-0.0	1.1	1.0	0.5	0.4	0.9	1.3	0.6
Prostate Cancer	0.6	0.9	5.2	-0.4	1.0	-0.3	0.7	0.9	0.6	2.3	0.3	0.8	0.7	1.6	0.8	1.3	0.6	0.3	0.4	-0.4	0.6
Blood White Count	0.6	4.1	7.5	-2.7	-2.2	-2.0	-0.7	-2.0	-1.4	-1.1	-2.5	-2.2	-2.0	-1.8	-2.7	-1.1	-1.3	-1.8	-2.6	-2.7	-1.9
Waist Hip Ratio (WHR)	0.6	2.6	4.8	2.2	1.5	1.4	0.5	1.3	1.5	0.9	2.2	1.0	1.0	-0.9	1.8	1.1	1.4	2.1	2.1	2.2	2.0
Ever used hormone-replacement therapy (HRT)	0.6	0.8	3.5	-1.0	-0.4	-0.7	-1.4	0.7	-0.5	-0.4	-0.2	0.8	1.2	0.4	0.1	0.3	-0.8	-1.9	-0.4	-0.9	-1.6
Fed-up feelings	0.6	1.1	3.0	0.8	0.6	1.6	0.6	1.5	1.1	0.2	1.1	1.3	1.7	-0.8	0.5	1.4	1.4	-0.1	1.0	0.8	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.3	-1.5	-0.4	0.3	1.1	0.2	-0.2	0.4	-1.4	-0.3	-0.0	0.1	-1.3	0.4	0.6	-1.4	-1.0	-1.5	-0.9
Qualifications: None of the above	0.6	1.2	3.3	0.2	0.7	1.8	1.4	1.7	0.6	0.8	0.3	1.6	1.5	1.5	0.7	1.4	1.2	-0.8	1.0	0.2	-0.3
Time employed in main current job	0.6	0.7	3.1	-0.8	0.4	-0.1	0.7	0.7	0.5	1.5	-0.2	0.8	0.5	1.8	0.4	1.3	0.2	-0.7	0.3	-0.9	-0.3
Depression (self-reported)	0.6	0.7	2.0	-1.4	-0.9	0.3	0.7	0.2	-0.8	0.2	-1.3	-0.6	-0.1	0.0	-1.2	-0.2	0.1	-1.1	-0.8	-1.4	-0.8
Loud music exposure frequency	0.6	0.7	2.1	-0.1	0.5	0.6	0.1	1.3	0.4	1.0	0.7	1.3	1.2	1.1	0.8	1.5	0.7	-0.4	0.8	-0.2	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.2	0.5	0.4	0.5	-0.7	1.8	0.3	1.2	1.3	1.2	1.5	-0.9	1.4	1.2	-0.1	-0.2	1.6	0.6	-0.0
Mineral and other dietary supplements	0.6	0.8	1.9	0.6	1.1	0.8	1.0	0.3	0.6	0.9	0.7	0.5	0.1	1.3	0.6	0.8	1.1	1.4	0.7	0.5	1.4
Osteoarthritis (self-reported)	0.6	0.8	3.3	1.2	0.5	1.1	0.4	-0.1	0.2	-0.1	1.1	-0.0	-0.5	-0.6	0.5	0.1	1.0	1.8	1.0	1.1	1.4
Medication: Aspirin	0.6	0.8	2.4	1.3	0.9	0.8	0.5	0.5	0.6	0.4	1.0	0.3	0.3	0.4	1.0	0.0	0.7	1.5	1.1	1.3	1.4
Average weekly beer plus cider intake	0.6	0.9	4.0	-0.1	0.4	0.3	0.9	1.5	1.4	1.3	0.3	1.1	1.4	1.0	0.7	2.0	0.7	-0.6	0.8	-0.1	-0.1
Pain experienced in last month	0.6	1.0	2.7	-0.6	-1.1	-1.1	-1.6	-0.8	-0.8	-1.2	-0.4	-0.6	-0.4	-1.6	-0.7	-0.8	-1.5	-1.1	-0.9	-0.5	-1.2
Impedance of whole body	0.6	3.0	7.2	-2.7	-1.7	-2.0	-2.7	-0.0	-2.1	0.8	-1.3	-0.8	-0.3	-1.3	-0.7	-0.3	-2.4	-2.3	-0.8	-2.6	-2.1
Age at First Birth	0.5	0.8	1.7	1.1	0.8	0.2	-0.0	0.9	1.3	0.3	1.3	1.2	1.3	-0.2	1.1	1.3	0.4	0.3	0.8	1.1	0.4
BMI	0.5	2.6	6.7	-1.0	-1.8	-1.6	-0.7	-2.0	-0.8	-2.3	-1.9	-1.7	-1.4	-0.8	-2.0	-1.5	-1.4	-1.4	-2.6	-1.1	-1.5
Systolic Blood Pressure	0.5	2.3	6.7	1.5	0.7	2.6	0.4	2.0	0.3	1.6	1.8	0.9	1.4	0.5	1.5	1.1	1.1	1.7	2.6	1.5	1.7
Neuroticism	0.5	1.2	2.9	0.2	1.1	1.4	1.7	1.2	1.3	1.3	0.4	1.2	1.2	1.4	0.3	1.7	1.5	-0.0	0.5	0.1	0.5
Sensitivity / hurt feelings	0.5	0.8	2.6	-1.4	-0.8	0.3	-0.1	-0.1	-1.2	-0.5	-1.2	-0.4	-0.4	-0.6	-1.1	-0.6	-0.2	-1.6	-0.7	-1.4	-1.3
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.3	1.1	0.4	0.2	-0.9	-0.1	-0.3	-0.6	0.7	-0.3	-0.5	-0.9	0.8	-1.0	-0.3	1.1	0.7	1.0	0.7
Diabetes (mother)	0.5	0.6	1.9	-0.3	-0.9	-0.6	-1.1	-0.8	-1.0	-0.6	-0.7	-0.8	-0.7	-0.5	-0.3	-1.1	-1.4	-0.5	-0.5	-0.3	-0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.8	0.1	0.8	0.4	0.8	1.1	0.9	0.9	0.3	1.0	1.3	0.9	0.6	1.3	0.6	-0.3	0.4	0.2	0.1
High blood pressure (mother)	0.5	0.7	3.8	-0.3	0.0	1.7	2.0	0.6	0.0	0.5	-0.6	0.0	0.3	1.3	-0.5	0.7	1.4	0.0	0.2	-0.3	0.3
Allergy	0.5	1.1	1.9	0.8	1.1	1.2	0.8	1.2	0.8	1.3	0.9	1.2	1.0	1.2	1.2	1.3	1.0	0.6	1.4	0.8	0.8
Fluid intelligence score	0.5	1.0	3.5	0.6	-0.9	-0.1	-0.4	-1.2	-0.7	-1.9	-0.2	-1.3	-1.4	-1.7	-0.6	-1.7	-0.5	0.6	-0.2	0.7	0.0
Alcohol intake versus 10 years previously	0.5	0.8	2.2	-0.7	-0.8	-0.6	-1.3	-0.4	-1.5	-1.0	-0.7	-0.5	-0.3	-0.6	-0.4	-1.2	-1.1	-1.1	-0.7	-0.7	-1.2
Qualifications: A levels/AS levels or equivalent	0.5	1.1	4.5	1.2	-0.1	-0.2	-1.3	-1.0	-0.3	-0.7	1.1	-0.8	-0.9	-2.1	0.1	-1.0	-0.4	1.9	0.2	1.3	1.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	3.1	0.7	-0.1	-1.5	-0.8	-1.8	0.3	-1.3	0.0	-0.8	-1.2	-1.3	-0.2	-1.0	-1.0	0.7	-0.8	0.8	0.2
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.9	1.3	1.0	-0.2	0.1	-0.0	1.2	-0.1	1.0	0.8	0.6	0.1	0.9	0.3	0.2	0.8	0.3	1.4	0.7
Medication: Omeprazole	0.5	0.6	2.3	-0.5	-0.5	-1.5	-1.2	-0.6	-0.7	-0.3	-0.8	-0.4	-0.4	0.2	0.2	-0.7	-1.4	-0.7	-0.5	-0.5	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.2	-0.7	-0.6	-0.9	-0.4	-0.7	-0.6	-0.2	-0.9	-0.7	-1.0	-0.3	-0.6	-0.8	-1.1	-0.8	-0.7	-0.8	-0.8
Financial situation satisfaction	0.5	0.6	1.8	0.0	0.6	0.9	1.0	1.3	0.9	1.2	0.2	0.7	0.8	0.2	0.6	1.4	0.9	-0.1	1.0	0.0	0.3
Depressed Affect (Nagel 2018)	0.4	0.9	2.4	0.0	0.6	1.3	1.4	1.4	1.1	0.9	0.1	1.2	1.4	0.8	0.2	1.6	1.2	-0.8	0.5	-0.0	-0.2
Coronary Artery Disease (CAD)	0.4	0.5	2.5	0.3	0.6	0.5	1.3	0.4	0.7	0.9	0.3	0.5	0.2	1.6	0.6	0.8	0.6	0.5	0.7	0.4	0.6
Fasting Glucose	0.4	0.4	1.5	0.5	0.5	1.2	0.3	0.7	-0.0	0.2	0.7	0.4	0.7	1.1	0.4	0.2	0.7	0.8	0.7	0.5	0.8
Blood Platelet Count	0.4	4.5	10.0	2.5	1.4	2.0	-0.1	2.8	2.3	0.9	2.8	2.6	3.2	-0.6	2.6	2.6	1.3	0.7	2.8	2.5	1.0
Relative age of first facial hair	0.4	0.7	1.5	1.1	1.1	1.0	0.9	0.7	0.6	0.5	0.6	0.3	-0.0	-0.0	1.1	-0.0	0.9	1.1	1.2	1.1	1.0
Systolic blood pressure, automated reading	0.4	1.3	3.7	0.9	0.7	1.4	0.4	1.6	0.4	1.2	1.0	1.2	1.4	1.3	1.6	1.2	0.5	0.6	1.9	0.9	0.7
Medication: Co-codamol	0.4	0.5	2.3	0.8	0.1	0.6	0.3	-0.4	0.3	-0.7	0.6	-0.3	-0.5	-1.5	-0.2	-0.3	0.8	1.2	0.3	0.7	0.9
Severe depression (siblings)	0.4	0.4	1.1	0.3	0.4	0.7	0.6	0.8	0.9	0.7	0.7	0.5	0.9	-0.1	0.0	1.1	0.9	0.3	0.3	0.4	0.5
Heart attack	0.4	0.6	2.2	1.5	0.8	0.6	-0.0	0.0	0.7	-0.5	0.9	0.4	0.3	-0.0	0.8	-0.2	0.3	1.1	0.6	1.4	0.9
Length of working week for main job	0.4	0.5	1.3	1.1	0.6	0.8	0.7	0.2	0.7	0.1	0.8	0.2	0.1	-0.6	0.3	-0.0	0.9	1.1	0.5	1.1	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.1	0.1	0.8	0.6	0.4	1.4	0.5	1.4	0.4	0.9	1.1	0.3	0.9	0.9	0.6	-0.1	0.9	0.2	0.2
Migraine (self-reported)	0.4	0.4	2.9	0.3	0.6	0.7	1.7	0.1	0.5	1.1	-0.1	-0.3	-0.6	0.1	0.1	-0.0	0.7	0.8	0.4	0.3	0.9
Pulse rate, automated reading	0.4	1.2	3.5	1.8	1.4	0.3	0.6	0.4	1.3	-0.1	1.2	1.2	0.8	1.0	1.6	0.3	0.7	1.0	1.1	1.9	0.9
Number of full sisters	0.4	0.4	1.3	0.0	-0.8	-1.0	-1.1	-0.8	-0.5	-0.9	-0.2	-0.6	-0.4	-0.5	-0.3	-0.7	-1.1	-0.2	-0.8	0.1	-0.4
Family relationship satisfaction	0.4	0.5	2.1	0.2	0.6	1.3	1.5	0.8	0.5	0.8	-0.2	0.3	0.5	0.9	0.2	0.5	0.8	0.1	0.4	0.1	0.5
Ever taken oral contraceptive pill	0.4	0.4	1.0	-0.9	-0.4	1.0	1.0	0.5	-0.1	0.4	-0.6	-0.3	-0.2	-0.7	-0.8	0.4	0.7	-0.7	0.1	-1.0	-0.4
Hearing aid user	0.4	0.5	2.6	0.3	-0.5	-0.6	-1.3	-0.5	-0.5	-1.6	-0.1	-0.2	0.0	-0.9	0.0	-0.9	-0.8	-0.6	-0.3	0.3	-0.8
Age started oral contraceptive pill	0.4	0.5	1.7	0.5	0.5	-0.2	-0.9	0.6	0.3	-0.0	0.9	1.2	1.1	0.8	1.3	0.7	-0.2	-0.1	1.0	0.5	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.0	-0.3	-0.4	-1.3	-1.3	-0.4	-0.8	-0.5	-0.7	-0.4	-0.6	0.2	0.5	-0.9	-1.4	-0.5	-0.1	-0.2	-0.8
Basal cell carcinoma (self-reported)	0.4	0.4	1.6	-0.2	0.5	0.9	0.5	0.8	-0.6	1.3	0.1	0.2	0.3	1.2	0.4	0.3	0.5	0.6	0.7	-0.3	0.7
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.8	1.4	0.6	0.5	-0.0	-0.0	0.5	-0.5	0.8	0.2	0.1	-0.0	0.7	-0.3	0.2	1.1	0.6	1.3	0.9
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.6	0.4	-0.5	-0.4	-0.4	-1.4	-0.4	-1.0	-0.1	-1.5	-1.6	-1.0	-0.8	-1.2	-0.2	1.5	-0.4	0.4	1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.9	-0.5	-0.5	0.8	0.9	-0.0	-0.8	0.2	-0.6	-1.0	-0.7	0.4	-0.8	-0.7	0.1	0.3	-0.1	-0.5	0.3
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.2	-0.8	-0.3	0.8	1.1	0.6	0.3	0.1	-0.9	-0.2	0.3	-0.5	-0.9	0.6	1.0	-0.9	-0.4	-0.9	-0.4
Ever had hysterectomy (womb removed)	0.3	0.3	1.1	0.9	0.4	-1.0	-0.5	-0.5	0.8	-0.3	0.6	0.0	-0.1	-0.2	0.7	0.1	-0.4	0.8	0.2	0.9	0.6
Diabetes (father)	0.3	0.4	1.7	0.4	-0.2	1.3	1.1	0.0	-0.2	0.1	0.0	-0.7	-0.6	-0.7	-0.4	-0.3	0.7	0.9	0.5	0.4	0.8
Impedance of leg (right)	0.3	1.2	4.6	-0.8	0.4	-0.3	-0.9	1.7	0.3	2.2	0.6	1.5	1.7	0.4	1.1	1.8	-0.4	-1.1	0.9	-0.7	-0.6
Current tobacco smoking	0.3	0.6	1.7	0.1	0.7	0.3	1.3	0.6	1.2	1.3	0.1	0.5	0.8	1.0	0.2	1.2	0.8	0.2	0.1	0.1	0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.0	-0.8	-0.6	-0.3	-0.5	0.0	-0.9	-0.2	-0.7	-0.2	-0.3	0.1	-0.2	-0.6	-0.7	-1.0	-0.1	-0.8	-1.0
Nervous feelings	0.3	0.5	2.1	0.0	0.7	0.6	1.2	0.3	0.7	1.4	0.2	0.4	0.3	1.0	0.1	0.8	1.0	0.7	0.1	0.1	0.9
Had other major operations	0.3	0.4	2.1	0.1	-0.4	-0.4	-1.5	-0.1	-0.5	-0.9	0.1	0.1	0.4	-1.2	0.1	-0.4	-0.8	-0.6	-0.2	0.1	-0.7
Illnesses of mother	0.3	0.4	1.6	0.6	0.4	-0.5	-0.6	-0.5	0.0	0.1	0.6	-0.4	-0.9	-0.7	0.4	-0.8	-0.3	1.3	0.3	0.6	0.9
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.2	1.1	0.5	0.4	0.5	0.3	0.6	0.2	0.4	0.3	0.2	0.1	1.0	0.2	0.3	0.6	1.0	1.1	0.6
Medication: Amlodipine	0.3	0.5	2.4	0.7	-0.4	-0.2	-0.9	-0.9	0.1	-1.5	0.5	-0.6	-0.3	-1.0	-0.5	-0.6	-0.1	0.7	-0.6	0.6	0.4
Emphysema/chronic bronchitis	0.3	0.3	1.4	0.4	0.2	-0.2	-0.4	0.7	0.7	-0.2	0.5	0.8	1.2	-0.5	0.5	0.7	0.2	-0.6	0.2	0.4	-0.4
Suffer from ‘nerves’	0.3	0.5	1.9	-0.2	0.6	0.7	1.2	0.4	0.4	1.2	-0.1	0.5	0.6	1.4	-0.1	1.0	0.8	0.1	-0.1	-0.2	0.4
Leg pain on walking	0.3	0.4	1.0	0.9	-0.0	-0.2	-1.0	0.1	0.4	-0.6	0.9	0.5	0.3	-0.9	0.8	0.1	-0.4	0.1	0.6	0.9	-0.1
Loneliness, isolation	0.3	0.4	1.5	0.7	0.8	1.2	0.8	0.4	0.2	0.4	0.4	0.1	-0.1	-0.3	0.4	0.0	0.8	1.1	0.7	0.7	1.0
Smoking status: Current	0.3	0.5	2.0	-0.2	0.6	-0.2	1.0	0.5	1.0	1.4	-0.1	0.5	0.7	1.2	0.2	1.1	0.5	0.0	-0.1	-0.2	0.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.5	0.7	0.7	-0.1	0.6	0.2	1.2	0.3	0.4	0.4	0.6	0.3	0.6	0.7	0.5	0.6	0.3	0.8	0.7
Number of operations (self-reported)	0.3	0.5	2.5	-0.8	-0.7	0.1	-0.1	0.3	-0.3	-0.9	-0.9	-0.1	0.5	-0.8	-0.7	0.0	-0.0	-1.6	-0.6	-0.8	-1.3
Diastolic blood pressure, automated reading	0.3	1.1	2.5	1.1	1.1	1.1	1.6	0.6	0.8	1.3	0.5	0.4	0.1	1.2	1.1	0.5	0.7	1.4	1.3	1.1	1.4
Unable to work because of sickness or disability	0.3	0.3	1.1	0.0	0.4	0.8	0.9	0.6	0.6	0.6	0.3	0.4	0.5	0.7	-0.0	0.9	1.1	0.3	0.3	-0.0	0.5
Heart disease (siblings)	0.3	0.3	1.1	0.9	0.5	0.4	0.1	0.1	0.5	0.2	1.1	0.5	0.2	-0.3	0.5	0.3	0.4	0.8	0.7	0.8	0.8
Schizophrenia (2018)	0.2	0.5	1.3	0.7	1.1	-0.5	0.1	0.4	1.1	0.5	0.6	0.9	0.9	0.5	1.1	0.8	0.2	0.3	0.3	0.7	0.4
Crohns Disease (2017)	0.2	0.5	1.3	-0.4	-0.7	0.3	0.5	-0.5	-0.7	-0.6	-1.0	-1.2	-0.9	-0.0	-1.0	-1.0	-0.0	0.0	-0.7	-0.5	-0.1
Crohns Disease (2012)	0.2	0.4	2.5	-0.1	-0.2	1.0	1.6	-0.2	0.3	-0.4	-0.6	-0.5	-0.3	-0.0	-1.0	-0.1	1.0	0.2	-0.4	-0.1	0.3
Schizophrenia (2014)	0.2	0.4	1.3	0.2	0.6	-0.5	-0.5	0.7	0.3	-0.1	0.1	1.1	1.1	0.6	1.0	0.3	-0.4	-1.0	0.2	0.3	-0.8
Respiratory disease	0.2	0.5	2.5	0.3	-0.5	-1.0	-1.6	-0.6	0.0	-0.7	0.8	-0.1	0.1	-1.4	-0.0	-0.1	-0.7	0.2	-0.4	0.4	-0.1
Chronotype (morning person)	0.2	0.5	1.8	-0.4	-0.2	-0.7	0.5	-1.0	0.4	-0.9	-0.8	-0.4	-0.5	-0.8	-1.0	-0.4	-0.1	-0.7	-1.3	-0.4	-0.6
Number of treatments/medications taken	0.2	0.4	1.6	1.1	0.5	0.4	-0.1	0.2	0.4	0.1	0.9	0.0	0.2	-0.0	0.6	-0.1	0.4	1.3	0.5	1.0	1.1
Supplements: Zinc	0.2	0.2	0.4	0.3	0.5	0.6	0.7	0.5	0.7	0.0	0.1	0.5	0.3	-0.5	0.4	0.4	0.5	-0.2	0.5	0.3	-0.1
Impedance of leg (left)	0.2	0.9	2.7	-1.4	-0.2	-0.5	-1.2	1.2	-0.4	1.6	-0.1	0.7	1.0	0.0	0.5	1.0	-0.7	-1.4	0.4	-1.3	-1.0
Hair/balding pattern: Pattern 2	0.2	0.2	0.8	0.8	0.6	-0.1	0.1	0.1	0.4	0.0	0.6	0.1	0.1	-0.4	0.5	-0.1	0.2	0.9	0.3	0.8	0.7
Had menopause	0.2	0.2	1.0	-0.3	-0.1	-1.0	-0.5	-1.0	-0.1	-0.5	-0.2	-0.1	-0.4	0.2	-0.3	-0.4	-0.5	-0.2	-0.7	-0.2	-0.3
Illnesses of siblings	0.2	0.2	1.1	-0.7	0.0	0.1	0.8	0.0	-0.1	0.9	-0.5	-0.2	-0.2	1.1	-0.4	0.3	0.3	0.2	-0.2	-0.7	0.3
Hair/balding pattern: Pattern 3	0.2	0.3	1.1	0.1	0.6	0.2	0.4	0.4	0.5	1.0	0.7	0.7	0.7	0.3	0.2	0.9	0.6	0.4	0.2	0.2	0.5
Medication: Lansoprazole	0.2	0.2	0.7	0.8	0.4	-0.4	-0.0	-0.5	0.3	-0.2	0.3	-0.0	-0.4	-0.2	0.7	-0.3	-0.1	0.7	0.4	0.8	0.4
Lung cancer (father)	0.2	0.3	0.7	0.7	0.4	0.1	0.2	0.0	0.5	0.0	0.5	0.0	-0.2	-0.8	0.6	0.4	0.4	0.8	0.8	0.7	0.6
Hair/balding pattern: Pattern 4	0.2	0.4	1.3	-0.5	-0.5	-0.2	-0.9	0.2	-0.2	-0.1	0.1	0.7	1.0	0.6	-0.1	0.8	-0.5	-1.1	-0.2	-0.5	-0.9
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.7	0.4	-0.4	1.3	1.0	0.1	-0.3	-0.4	-0.2	-0.4	-0.5	-0.2	-0.2	-0.4	0.3	0.2	0.5	0.4	0.1
High blood pressure (siblings)	0.2	0.3	1.1	1.1	0.1	0.2	-0.5	-0.0	0.2	-0.6	0.9	0.1	0.2	-0.8	0.4	-0.2	-0.0	0.6	0.4	1.1	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.7	-0.4	-0.1	0.8	0.8	0.8	-0.2	0.8	-0.2	-0.1	0.4	0.4	-0.4	0.3	0.7	0.0	0.0	-0.4	0.3
Had major operations	0.2	0.2	0.7	-0.2	-0.1	0.6	0.6	-0.1	-0.1	-0.8	-0.8	0.0	-0.2	-0.2	-0.3	-0.3	0.3	-0.9	-0.1	-0.2	-0.8
Age at last live birth	0.2	0.3	0.8	-0.6	-0.7	-0.4	-0.9	-0.4	-0.8	-0.0	-0.2	-0.4	-0.4	-0.6	-0.3	-0.2	-0.7	-0.4	-0.3	-0.6	-0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.4	0.4	-0.2	-0.3	0.1	-1.2	0.1	-0.9	0.2	-0.5	-0.7	-0.4	-0.6	-0.5	0.1	0.8	-0.6	0.4	0.5
Supplements: Vitamin C	0.2	0.2	0.9	-0.7	-0.4	0.1	0.3	-0.3	-0.2	-0.3	-0.4	-0.5	-0.3	-0.4	-0.9	-0.1	0.2	-0.2	-0.7	-0.7	-0.1
Long-standing illness, disability or infirmity	0.2	0.3	1.0	1.0	0.1	0.2	-1.0	0.3	-0.1	-0.4	0.9	0.5	0.4	-0.3	0.8	-0.3	-0.3	0.3	0.6	0.9	0.1
Qualifications: nursing, teaching	0.2	0.3	1.0	-0.8	-0.4	0.3	0.0	-0.3	-1.0	0.2	-0.7	-0.8	-0.9	0.2	-0.6	-0.7	-0.1	-0.0	-0.2	-0.9	-0.1
Commuting to job workplace: Walk	0.2	0.2	1.1	0.2	0.6	-0.5	-0.6	-0.2	0.2	-0.2	0.4	0.9	0.5	1.1	0.7	0.1	-0.2	-0.2	0.0	0.3	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	-0.6	-0.4	-0.4	-0.3	-0.4	-0.7	-0.6	-0.7	-0.5	-0.4	0.3	-0.5	-0.7	-0.1	-0.3	-0.6	-0.6	-0.4
Osteoporosis (self-reported)	0.2	0.3	0.6	0.4	0.8	-0.5	-0.3	0.2	0.7	0.8	0.7	0.6	0.6	-0.1	0.4	0.4	0.1	0.5	-0.2	0.4	0.6
Illnesses of father: None of the above (group 1)	0.2	0.3	0.9	-0.7	-0.4	0.2	0.1	0.1	-0.3	-0.6	-0.7	-0.2	-0.1	-0.7	-0.6	-0.3	0.1	-1.0	-0.3	-0.6	-0.9
Average weekly champagne plus white wine intake	0.2	0.3	1.1	0.2	-0.3	0.8	-0.7	0.7	-0.1	-0.4	0.8	0.6	0.9	-1.1	0.1	0.3	0.2	-0.5	0.5	0.2	-0.4
Medication: Blood pressure	0.2	0.4	2.0	0.7	-0.3	-0.1	-1.4	-0.5	-0.7	-0.8	0.7	-0.4	-0.2	-0.8	0.2	-0.9	-0.5	1.0	0.1	0.7	0.5
Illnesses of father: High blood pressure	0.2	0.2	1.1	0.6	-0.3	-0.1	-0.2	-0.6	0.4	-1.0	0.5	-0.1	0.2	-0.6	-0.5	0.1	0.1	0.3	-0.6	0.6	0.2
Leg fat percentage (left)	0.2	0.6	2.5	-0.7	-0.5	-0.8	-1.2	0.1	-0.2	-0.8	-0.6	0.3	0.6	-0.1	-0.1	0.1	-0.7	-1.6	-0.8	-0.8	-1.3
Commuting to job workplace: Cycle	0.2	0.3	1.0	-0.5	-0.8	0.5	-0.0	-0.1	-1.0	-0.6	-0.6	-0.4	-0.2	0.0	-0.5	-0.6	-0.3	-0.7	-0.0	-0.4	-0.7
Supplements: Calcium	0.2	0.2	0.9	-0.2	-0.5	0.1	-0.5	0.1	-0.5	-0.6	-0.2	0.1	0.3	-0.2	-0.2	-0.4	-0.5	-0.9	-0.2	-0.1	-0.9
Ovarian Cancer	0.1	0.1	0.7	-0.2	0.1	0.4	0.4	0.3	-0.3	-0.1	-0.5	0.1	0.5	0.8	-0.2	-0.1	0.3	-0.4	-0.5	-0.2	-0.3
Mean Putamen Volume	0.1	0.1	0.4	-0.2	-0.1	0.3	0.1	0.2	0.2	-0.2	-0.1	0.2	0.3	-0.6	-0.2	0.3	0.3	-0.4	-0.1	-0.3	-0.3
Blood Red Count	0.1	1.3	7.1	-1.0	0.6	0.4	2.7	0.3	1.1	1.6	-1.6	-0.2	0.3	1.4	-1.0	1.2	1.1	-0.6	-1.2	-1.0	0.2
Lung FEV1/FVC ratio	0.1	0.7	3.6	1.3	0.6	0.5	0.0	-0.5	-0.4	-0.4	0.4	-0.7	-0.9	0.0	0.6	-1.1	-0.1	1.9	0.6	1.2	1.4
Lung FVC	0.1	0.7	2.4	-1.5	-0.3	0.1	0.3	0.2	-1.0	0.6	-0.9	0.4	0.2	1.4	-0.4	0.3	-0.5	-1.5	-0.3	-1.4	-1.3
Hair Pigment	0.1	1.9	5.3	1.0	1.1	1.7	1.9	-0.9	-1.2	-0.4	-0.6	-0.5	-2.0	2.3	0.8	-2.2	0.7	1.9	1.2	0.8	1.3
Hand grip strength (left)	0.1	0.4	1.2	0.0	0.3	-0.5	-1.0	0.1	0.0	-0.6	0.1	0.9	0.9	0.5	0.4	-0.1	-0.6	-1.1	-0.4	0.1	-1.0
Average weekly spirits intake	0.1	0.1	0.6	0.1	0.2	-0.7	-0.2	-0.6	0.1	0.5	0.3	-0.2	-0.3	-0.3	0.0	0.2	-0.3	0.7	-0.3	0.1	0.5
Hand grip strength (right)	0.1	0.4	1.8	0.3	-0.2	-0.3	-1.1	-0.5	-0.4	-1.3	0.1	0.1	0.1	-0.6	-0.1	-0.9	-0.7	-0.5	-0.6	0.3	-0.7
Taking other prescription medications	0.1	0.2	0.6	0.8	0.5	0.3	-0.1	0.5	0.3	0.3	0.6	0.4	0.6	0.3	0.6	-0.1	0.3	0.5	0.3	0.7	0.6
Body mass index (BMI)	0.1	0.6	3.8	0.2	-0.6	-0.9	-0.9	-0.9	-0.0	-2.0	-0.5	-0.5	-0.3	-0.9	-0.4	-0.8	-0.7	-0.7	-1.0	0.1	-0.8
Pulse rate	0.1	0.2	1.5	-0.3	0.2	-0.9	0.4	-0.2	0.3	0.1	-0.6	0.3	0.0	1.2	0.2	-0.1	-0.4	-0.7	-0.4	-0.2	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.4	-0.0	0.3	-0.3	-0.2	0.1	-0.0	0.5	0.3	-0.2	-0.4	-0.3	0.3	-0.3	0.0	0.6	0.3	-0.0	0.5
Asthma	0.1	0.3	1.2	0.5	0.1	-0.5	-1.0	0.3	0.4	0.1	1.1	0.3	0.5	-0.9	0.5	0.4	-0.0	0.4	0.3	0.5	0.3
Exposure to tobacco smoke at home	0.1	0.1	0.7	-0.3	0.0	-0.9	-0.7	0.0	-0.3	0.2	-0.0	-0.2	-0.1	-0.2	0.0	-0.3	-0.4	0.0	-0.4	-0.2	-0.0
Tense / ‘highly strung’	0.1	0.2	0.8	-0.8	-0.3	0.1	0.6	-0.3	0.0	0.4	-0.6	-0.3	-0.2	0.6	-0.9	0.3	0.0	-0.5	-0.8	-0.8	-0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.2	-0.3	-0.1	-0.5	-1.1	-0.0	-0.0	-0.2	0.5	0.4	0.4	-0.2	-0.1	0.6	-0.2	-0.3	-0.4	-0.4	-0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.7	0.2	0.3	-0.4	0.3	0.0	0.8	0.6	0.1	-0.0	-0.0	0.1	0.2	0.5	0.1	0.4	0.1	0.2	0.5
Leg fat percentage (right)	0.1	0.5	2.5	-0.5	-0.2	-0.8	-1.0	0.4	0.2	-0.5	-0.3	0.6	1.0	0.1	0.2	0.5	-0.6	-1.6	-0.5	-0.5	-1.2
Comparative body size at age 10	0.1	0.2	1.0	-0.3	-0.3	-0.5	0.4	-0.7	0.1	-0.1	-0.5	-0.7	-0.5	0.2	-0.9	-0.2	0.0	0.2	-1.0	-0.4	0.2
Number of children fathered	0.1	0.1	0.5	0.3	-0.0	-0.2	0.0	-0.5	0.1	-0.6	-0.0	-0.4	-0.7	-0.5	-0.2	-0.5	-0.0	0.4	-0.2	0.2	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.4	0.1	0.1	0.0	-0.1	0.0	0.4	0.1	0.5	0.3	0.6	-0.1	-0.2	0.6	0.3	0.1	-0.3	0.2	0.2
Shortness of breath walking on level ground	0.1	0.2	0.9	-0.2	0.1	0.0	0.4	0.5	0.5	0.2	-0.2	0.5	0.5	0.9	0.2	0.7	0.2	-0.6	0.0	-0.3	-0.3
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.8	0.4	-0.2	-0.1	-0.5	0.0	0.1	-0.2	0.2	-0.0	0.0	-0.9	0.2	0.1	-0.4	-0.2	0.1	0.3	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.4	0.2	0.3	-0.4	-0.4	-0.1	0.1	0.4	0.3	0.0	0.0	0.5	0.4	0.0	-0.1	0.6	0.1	0.3	0.5
Medication for cholesterol	0.1	0.1	0.7	0.1	0.1	0.0	0.5	0.3	0.7	0.4	0.1	0.2	0.1	-0.9	0.1	0.6	0.1	-0.3	0.3	0.1	-0.2
Asthma (self-reported)	0.1	0.2	1.1	0.2	-0.1	-0.6	-1.1	0.1	0.2	-0.1	0.8	0.2	0.4	-1.0	0.2	0.2	-0.2	0.1	0.0	0.2	0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	0.2	-0.1	0.4	0.6	0.1	0.0	-0.2	-0.5	-0.0	-0.0	0.3	0.3	-0.1	-0.1	-0.3	0.3	0.2	-0.3
Commuting to job workplace: Public transport	0.1	0.1	0.6	0.5	0.2	-0.2	-0.2	-0.4	0.5	-0.8	0.4	0.3	0.3	0.0	-0.1	0.1	0.3	0.4	-0.5	0.5	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.8	0.4	-0.4	-0.2	-0.6	-0.1	0.2	-0.9	0.3	0.1	0.4	-0.9	-0.1	-0.3	-0.3	-0.4	-0.1	0.5	-0.4
Medication: Bendroflumethiazide	0.1	0.1	0.5	-0.1	-0.6	0.7	0.0	0.2	-0.5	-0.1	0.1	-0.5	-0.2	-0.5	-0.4	0.1	0.2	0.4	0.4	-0.2	0.3
Heel T-Score	0.0	0.4	1.2	-0.7	-0.2	0.2	-0.9	0.6	-0.7	-0.0	0.1	0.8	0.9	0.3	0.2	0.3	-0.2	-1.1	0.3	-0.6	-1.0
Tanning	0.0	0.2	0.9	0.0	0.1	0.2	-0.2	0.5	0.3	-0.3	0.5	0.9	0.9	0.5	0.1	0.8	0.4	-0.6	0.0	-0.0	-0.4
Knee pain experienced in last month	0.0	0.1	0.3	-0.1	0.1	0.3	0.5	0.1	0.1	-0.3	-0.2	-0.1	-0.2	0.3	-0.1	-0.0	0.5	0.1	0.1	-0.1	0.1

Hub : Genes

C17orf57

Models

Trait associations