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chr9:93,630,445-96,338,382

Best TWAS P=1.53e-13 · Best GWAS P=1.56e-16 conditioned to 0.193

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ECM2	0.05	0.00	lasso	4	0.00	1.2e-01	7.3	-7.0	2.8e-12	-0.82	0.05	0.76	FALSE
2	GTEx	Artery Aorta	ECM2	0.11	0.10	lasso	10	0.09	1.1e-05	-4.2	-5.4	7.3e-08	-0.63	0.33	0.65	FALSE
3	GTEx	Brain Cerebellar Hemisphere	IPPK	0.17	0.22	lasso	13	0.16	6.8e-05	-5.1	-5.4	6.4e-08	-0.72	0.18	0.75	FALSE
4	GTEx	Cells Transformed fibroblasts	IPPK	0.11	0.09	lasso	8	0.07	7.8e-06	7.2	7.4	1.5e-13	0.95	0.04	0.96	TRUE
5	GTEx	Uterus	ZNF484	0.23	0.05	lasso	3	0.05	3.0e-02	6.6	-6.5	6.1e-11	-0.82	0.05	0.38	FALSE
6	METSIM	Adipose	ROR2	0.12	0.04	bslmm	639	0.05	3.2e-08	1.9	6.5	9.5e-11	0.14	1.00	0.00	TRUE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	ECM2	0.03	0.02	lasso	5	0.02	3.9e-05	7.7	-7.3	3.8e-13	-0.90	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IPPK	0.06	0.03	blup	49	0.04	5.8e-03	-3.6	6.0	2.3e-09	0.66	0.03	0.29	FALSE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	ROR2	0.17	0.00	blup	261	0.07	4.6e-03	6.8	5.9	3.5e-09	0.00	0.12	0.25	TRUE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BICD2	0.14	0.06	blup	52	0.07	5.2e-08	-4.3	-5.3	1.3e-07	-0.55	0.98	0.02	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	BICD2	0.10	0.03	blup	52	0.03	1.3e-02	-4.3	-5.2	1.8e-07	-0.60	0.03	0.11	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	BICD2	0.06	0.02	blup	52	0.05	2.9e-06	-3.9	-6.6	3.5e-11	-0.77	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IPPK	0.03	0.02	blup	51	0.01	3.2e-02	-3.5	5.9	4.6e-09	0.66	0.03	0.62	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CENPP	0.19	0.09	blup	158	0.08	7.1e-04	-3.6	5.3	1.1e-07	0.53	0.04	0.40	FALSE